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Nanotechnology Applications For Cancer Chemotherapy

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Nanotechnology Applications for Cancer Chemotherapy

Nanotechnology Applications for Cancer Chemotherapy Book
Author : Sanyog Jain,Kaisar Raza,Ashish Kumar Agrawal,Ankur Vaidya
Publisher : Elsevier
Release : 2020-09-30
ISBN : 0128178477
Language : En, Es, Fr & De

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Book Description :

Applications of Nanotechnology in Cancer Chemotherapy offers a complete and concise summary of nanotechnological interventions for cancer management. It highlights the basics of oncology, the cancer microenvironment, targets for active drug delivery, the underlying mechanisms and molecular pathways to enhance the drug delivery to the cancer site. The book discusses the principles of basic and innovative nanocarrier-based therapeutic approaches to modulate the progression of the disease. In addition, this book also explores the evolving targeting approaches specific to the cancer site and type. The scope of the book is not limited to targeted drug delivery for various cancers, but also explores the advancements in cancer imaging and diagnostics employing the nanotechnological tools. Emphasis has been given on the important evaluation techniques like in-vitro cell culture and in-vivo animal models to assess the performance of cancer nanomedicines. The book includes clinical study reports of various drug moieties explored using variety of nanoconstructs in myriad cancer conditions with the input of global market and pharmacoeconomics. Discusses how organic and inorganic nanoplatforms are being used in cancer treatment Shows how nanotechnology is being used to create new and more accurate diagnostic tools Surveys the current generation of cancer nanomedicines, assessing their advantages and challenges

Nanotheranostics for Cancer Applications

Nanotheranostics for Cancer Applications Book
Author : Prakash Rai,Stephanie A. Morris
Publisher : Springer
Release : 2018-11-12
ISBN : 3030017753
Language : En, Es, Fr & De

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Book Description :

This book is the first to focus specifically on cancer nanotheranostics. Each of the chapters that make up this comprehensive volume is authored by a researcher, clinician, or regulatory agency member known for their expertise in this field. Theranostics, the technology to simultaneously diagnose and treat a disease, is a nascent field that is growing rapidly in this era of personalized medicine. As the need for cost-effective disease diagnosis grows, drug delivery systems that can act as multifunctional carriers for imaging contrast and therapy agents could provide unique breakthroughs in oncology. Nanotechnology has enabled the development of smart theranostic platforms that can concurrently diagnose disease, start primary treatment, monitor response and initiate secondary treatments if required. In oncology, chemotherapeutics have been routinely used. Some drugs have proven effective but all carry risks of adverse side effects. There is growing interest in using remotely triggered drug delivery systems to limit cytotoxicity in the diseased area. This book reviews the use of theranostic nanoparticles for cancer applications over the past decade. First, it briefly discusses the challenges and limitations of conventional cancer treatments, and presents an overview of the use of nanotechnology in treating cancer. These introductory chapters are followed by those exploring cancer diagnosis and a myriad of delivery methods for nanotherapeutics. The book also addresses multifunctional platforms, treatment monitoring, and regulatory considerations. As a whole, the book aims to briefly summarize the development and clinical potential of various nanotheranostics for cancer applications, and to delineate the challenges that must be overcome for successful clinical development and implementation of such cancer theranostics.

Nanotechnology in Cancer Treatment

Nanotechnology in Cancer Treatment Book
Author : Steve N. Fiering ,Robert Ivkov
Publisher : MDPI
Release : 2020-12-16
ISBN : 3039363743
Language : En, Es, Fr & De

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Book Description :

The collection is diverse in the topics covered as well as the contributors, who come from across the globe. The overall topic is inherently a complex one since it integrates the exceptional complexity of cancer biology and treatment with the large and rapidly growing number of potential nanostructures and modifications that could be applied to treatment. In both cancer and nanotechnology, a very small change of a relevant variable can generate exceptional variability in biological outcome, creating inherent challenges to clinical adoption. As with many high-potential fields in medicine, the recognition of exceptional potential for nanotechnology in cancer therapy, with associated expectations of rapid clinical impact, has been followed by disappointingly slow progress that highlights not failure but rather unrealistic expectations for rapid progress. We have passed that period of expected rapid clinical impact for nanoparticle treatment of cancer and are now well-entrenched in the more realistic phase of exploiting the easiest applications, in this case packaging of established chemotherapy drugs, while carefully studying the exceptional numbers of relevant variables that must be evaluated for efficacy and safety of innovative strategies. Although never as rapid as hoped, the progress is clear and clinical impact is growing.

Cancer Nanotechnology

Cancer Nanotechnology Book
Author : Sang Hyun Cho,Sunil Krishnan
Publisher : Taylor & Francis
Release : 2016-04-19
ISBN : 1439878765
Language : En, Es, Fr & De

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Book Description :

Rapid advances in nanotechnology have enabled the fabrication of nanoparticles from various materials with different shapes, sizes, and properties, and efforts are ongoing to exploit these materials for practical clinical applications. Nanotechnology is particularly relevant in the field of oncology, as the leaky and chaotic vasculature of tumors—a hallmark of unrestrained growth—results in the passive accumulation of nanoparticles within tumors. Cancer Nanotechnology: Principles and Applications in Radiation Oncology is a compilation of research in the arena of nanoparticles and radiation oncology, which lies at the intersection of disciplines as diverse as clinical radiation oncology, radiation physics and biology, nanotechnology, materials science, and biomedical engineering. The book provides a comprehensive, cross-disciplinary survey of basic principles, research techniques, and outcomes with the goals of eventual clinical translation. Coverage includes A general introduction to fabrication, preferential tumor targeting, and imaging of nanoparticles The specific applications of nanomaterials in the realms of radiation therapy, hyperthermia, thermal therapy, and normal tissue protection from radiation exposure Outlooks for future research and clinical translation including regulatory issues for ultimate use of nanomaterials in humans Reflecting profound advances in the application of nanotechnology to radiation oncology, this comprehensive volume demonstrates how the unique physicochemical properties of nanoparticles lead to novel strategies for cancer treatment and detection. Along with various computational and experimental techniques, each chapter highlights the most promising approaches to the use of nanoparticles for radiation response modulation.

Nanotechnology and Nanomaterials in the Treatment of Life threatening Diseases

Nanotechnology and Nanomaterials in the Treatment of Life threatening Diseases Book
Author : Narenda Kumar,Rajiv Kumar
Publisher : William Andrew
Release : 2013-12-05
ISBN : 0323264506
Language : En, Es, Fr & De

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Book Description :

Nanotechnology and Nanomaterials in the Treatment of Life-threatening Diseases takes a scientific approach to nanotechnology and nanomaterials applications in medicine, while also explaining the core biological principles for an audience of biomedical engineers, materials scientists, pharmacologists, and medical diagnostic technicians. The book is structured by major disease groups, offering a practical, application-based focus for scientists, engineers, and clinicians alike. The spectrum of medical applications is explored, from diagnostics and imaging to drug delivery, monitoring, therapies, and disease prevention. It also focuses specifically on the synthesis of nanomaterials and their potential health risks (particularly toxicity). Nanomedicine — the application of nanomaterials and devices for addressing medical problems — has demonstrated great potential for enabling improved diagnosis, treatment, and monitoring of many serious illnesses, including cancer, cardiovascular and neurological disorders, HIV/AIDS, and diabetes, as well as many types of inflammatory and infectious diseases. Gain an understanding of how nanotechnologies and nanomaterials can be deployed in the fight against the major life-threatening diseases: cancer, neurological disorders (including Alzheimer's and Parkinson's), cardiovascular diseases, and HIV/AIDS Discover the latest developments in nanomedicine, from therapies and drug delivery to diagnostics and disease prevention The authors cover the health risks of nanomaterials as well as their benefits, considering toxicity and potential carcinogens

Multifunctional Theranostic Nanomedicines in Cancer

Multifunctional Theranostic Nanomedicines in Cancer Book
Author : Malay K. Das
Publisher : Academic Press
Release : 2021-03-26
ISBN : 0128217006
Language : En, Es, Fr & De

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Book Description :

Multifunctional Theranostic Nanomedicines in Cancer focuses on new trends, applications, and the significance of novel multifunctional nanotheranostics in cancer imaging for diagnosis and treatment. Cancer nanotechnology offers new opportunities for cancer diagnosis and treatment. Multifunctional nanoparticles harboring various functions—including targeting, imaging, and therapy—have been intensively studied with the goal of overcoming the limitations of conventional cancer diagnosis and therapy. Thus theranostic nanomedicines have emerged in recent years to provide an efficient and safer alternative in cancer management. This book covers polymer-based therapies, lipid-based therapies, inorganic particle-based therapies, photo-related therapies, radiotherapies, chemotherapies, and surgeries. Multifunctional Theranostic Nanomedicines in Cancer offers an indispensable guide for researchers in academia, industry, and clinical settings; it is also ideal for postgraduate students; and formulation scientists working on cancer. Provides a comprehensive resource of recent scientific progress and novel applications of theranostic nanomedicines Discusses treatment options from a pharmaceutical sciences perspective Includes translational science and targeted CNS cancer treatment

Nanotechnology in Cancer

Nanotechnology in Cancer Book
Author : Anshu Mathur
Publisher : William Andrew
Release : 2016-10-20
ISBN : 0323390811
Language : En, Es, Fr & De

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Book Description :

Nanotechnology in Cancer covers current nanotechnology-based nanotherapeutics involving gold nanoparticles, colloids, gels, magnetic nanoparticles, radiofrequency, gene therapy, biological particles, and the intermolecular interactions associated with nanoparticle based cancer therapy in vivo. Different cancer types and locations are considered alongside the corresponding treatment types, and the use of imaging technologies and animal models are also explored. Both scientific and clinical aspects are considered by authors coming from both fields, with the authors using their backgrounds from different disciplines to make the connection between cancer and effective drug delivery and therapeutic strategies. Authored by leaders from the scientific research and clinical communities who use their background from different disciplines to explore the connections between cancer and effective drug delivery and therapeutic strategies Brings together tumor biology, imaging technologies, nanomaterial platforms for drug delivery, therapeutic strategies, and reconstructive surgery Explores the clinical and regulatory challenges facing nanomedicine

Nanotechnology Based Precision Tools for the Detection and Treatment of Cancer

Nanotechnology Based Precision Tools for the Detection and Treatment of Cancer Book
Author : Chad A. Mirkin,Thomas J. Meade,Sarah Hurst Petrosko,Alexander H. Stegh
Publisher : Springer
Release : 2015-04-20
ISBN : 3319165550
Language : En, Es, Fr & De

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Book Description :

This book discusses emerging nanotechnology-based tools that have the potential to dramatically impact cancer research, diagnostics, and treatment. Cancer is a complex, devastating, and debilitating disease and, although much progress has been made, novel, more effective diagnostic and treatment options are still needed, especially for advanced cancers. The ultimate goal is to detect cancer early and non-invasively and to provide efficacious and targeted precision treatments that cause fewer harmful side effects. This book explains how nanotechnology can exploit the size-, shape-, and composition-dependent properties of nanomaterials to provide novel tools for precision cancer medicine. It will be of interest to researchers and professionals working in the fields of chemistry, biology, materials science and engineering, and medicine who want to learn more about this fascinating and fast-paced area of research.

Nanotheranostics

Nanotheranostics Book
Author : Mahendra Rai,Bushra Jamil
Publisher : Springer Nature
Release : 2019-11-22
ISBN : 3030297683
Language : En, Es, Fr & De

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Book Description :

This book is specifically designed to provide information about various nanocarriers currently developed under the emerging field of nanotheranostics for a sustained, controlled, and targeted co-delivery of diagnostic and therapeutic agents. Diverse theranostic applications of nanotechnology and their limitations are also addressed. It integrates nanobiotechnology with theranostic applications. The combined term nanotheranostics has diverse application particularly in chemotherapy and other infectious diseases.Among other topics addressed are antimicrobial resistance, targeting intra-cellular pathogens, viruses and bacteria, chemotherapy, cancer therapeutics, and inflammatory disorders. This interdisciplinary volume is essential for a diverse group of readers including nanotechnologists, microbiologists, biotechnologists, bioengineering and bioprocess industry.

Behaviors and Persistence of Nanomaterials in Biomedical Applications

Behaviors and Persistence of Nanomaterials in Biomedical Applications Book
Author : Domenico Cassano,Valerio Voliani
Publisher : John Wiley & Sons
Release : 2018-06-01
ISBN : 111941895X
Language : En, Es, Fr & De

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Book Description :

In the last two decades, several promising engineered nanomaterials that combine therapeutic features and imaging functionalities have been presented, but very few have arrived on the market. The purpose of this book is to collect and comprehensively discuss the advances in this current and exciting topic in order to promote and enhance its growth. In the first part, a general introduction about the main features of both organic and inorganic nanomaterials is provided. Then, the most promising and innovative applications for cancer treatment and diagnostic are introduced. In the second part, an analysis of the nanomaterials in the market for healthcare applications is presented. The issue of unwanted accumulation of metals in organisms after the designed action is then discussed. Finally, the most recent progresses in the design of nanomaterials that are able to escape from organisms after the selected action are comprehensively described, and the perspectives of this exciting field provided.

Nanostructures for Cancer Therapy

Nanostructures for Cancer Therapy Book
Author : Alexandru Mihai Grumezescu,Anton Ficai
Publisher : Elsevier
Release : 2017-04-11
ISBN : 0323461506
Language : En, Es, Fr & De

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Book Description :

Nanostructures for Cancer Therapy discusses the available preclinical and clinical nanoparticle technology platforms and their impact on cancer therapy, including current trends and developments in the use of nanostructured materials in chemotherapy and chemotherapeutics. In particular, coverage is given to the applications of gold nanoparticles and quantum dots in cancer therapies. In addition to the multifunctional nanomaterials involved in the treatment of cancer, other topics covered include nanocomposites that can target tumoral cells and the release of antitumoral therapeutic agents. The book is an up-to-date overview that covers the inorganic and organic nanostructures involved in the diagnostics and treatment of cancer. Provides an examination of nanoparticle delivery systems for cancer treatment, illustrating how the use of nanotechnology can help provide more effective chemotherapeutic treatments Examines, in detail, the different types of nanomaterials used in cancer therapy, also explaining the effect of each Provides a cogent overview of recent developments in the use of nanostructured materials in chemotherapeutics, allowing readers to quickly familiarize themselves with this area

Nanomedicine for Cancer Diagnosis and Therapy

Nanomedicine for Cancer Diagnosis and Therapy Book
Author : Arshi Malik,Sarah Afaq,Mohammed Tarique
Publisher : Springer Nature
Release : 2021-08-01
ISBN : 9811575649
Language : En, Es, Fr & De

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Book Description :

This book reviews the current applications and future prospects of nanomaterials in cancer diagnostics and therapy. Nanomaterials have recently emerged as a remarkable and promising tool for cancer therapy and diagnosis, due to their broad range of intrinsic molecular properties. To overcome the current limitations of nanoparticles in drug delivery systems, attempts have been made to synthesize nanoparticles from biological materials for targeted cancer therapy. This book provides concise evaluations of various potential bio-inspired platforms that mimic natural components of the body and offer effective and versatile drug delivery systems for cancer therapy. It also assesses the potential of nanoparticles to enhance the outcomes of cancer immunotherapy via immune cell activation and tumor microenvironment modulation. The book also summarizes in the applications of nanomaterials for the detection, prevention, and treatment of solid tumors and in the treatment of leukemia and lymphomas. In closing, it discusses ethical issues in nanomedicine, including risk assessment, risk management, and risk communication during clinical trials. The book offers offers a valuable source of information for students, academics, researchers, scientists, clinicians, and healthcare professionals working in nanotechnology and cancer research.

Drug Delivery Approaches and Nanosystems Volume 2

Drug Delivery Approaches and Nanosystems  Volume 2 Book
Author : Raj K. Keservani,Anil K. Sharma,Rajesh K. Kesharwani
Publisher : CRC Press
Release : 2017-11-15
ISBN : 1351846663
Language : En, Es, Fr & De

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Book Description :

This volume is a thorough presentation of the state-of-the-art research and developments in drug delivery systems using nanotechnology and its applications. The second of this two-volume set, it addresses the applications of nanotechnology or nano-sized materials in the medical field and the real-world challenges and complexities of current drug delivery methodologies and techniques. This volume includes 11 chapters that focus on the targeting facet of drug delivery systems. Targeting is a focused maneuver to achieve the specified goals, including achieving the desired result and reaching the specific location. Targeting has now been successfully achieved for several diseases/disorders; however, its role is noteworthy in cancer treatment where chemotherapy is a main course of approach. Nanotechnology-based products have great potential by virtue of their inherent features. This edited book provides a detailed application of nanotechnology in drug delivery systems in health care. The book discusses general principles of drug targeting, material of construction and technological concerns of nanoparticles, and different drug delivery systems and their preparation. Taken together, the informative chapters will provide researchers and scientists as well as faculty and students with valuable research on the effective use of new approaches in advanced drug delivery nanosystems. Volume 1 of the two-volume series is subtitled Novel Drug Carriers. The volumes are available separately or as a set.

Molecular Medicines for Cancer

Molecular Medicines for Cancer Book
Author : Deepak Chitkara,Anupama Mittal,Ram I. Mahato
Publisher : CRC Press
Release : 2018-09-03
ISBN : 1351978365
Language : En, Es, Fr & De

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Book Description :

The field of molecular medicine covers the medical interventions targeting molecular structures and mechanisms that are involved in disease progression. In cancer, several molecular mechanisms have been shown to impact its progression, aggressiveness and chemoresistance. Increasing evidence demonstrates the role of nanotechnology and outcome of molecular therapy. Several books have discussed molecular biology and mechanisms involved in cancer, but this text gives an account of molecular therapeutics in cancer relating to advancements of nanotechnology. It provides a description of the multidisciplinary field of molecular medicines and its targeted delivery to cancer using nanotechnology. Key Features: Provides current information in the multidisciplinary field of molecular medicines and its targeted delivery to cancer using nanotechnology Presents important aspects of nanotechnology in the site-specific delivery of anticancer agents Includes up to date information on oligonucleotide and gene based therapies in cancer Describes small targeted molecules, antibodies and oligonucleotides which have shown to selectively target the molecular structures thereby influencing signal transduction Facilitates discussion between researchers involved in cancer therapy and nanoscientists

Nanobiotechnology in Diagnosis Drug Delivery and Treatment

Nanobiotechnology in Diagnosis  Drug Delivery and Treatment Book
Author : Mahendra Rai,Mehdi Razzaghi-Abyaneh,Avinash P. Ingle
Publisher : John Wiley & Sons
Release : 2020-11-17
ISBN : 1119671868
Language : En, Es, Fr & De

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Book Description :

Presents nanobiotechnology in drug delivery and disease management Featuring contributions from noted experts in the field, this book highlights recent advances in the nano-based drug delivery systems. It also covers the diagnosis and role of various nanomaterials in the management of infectious diseases and non-infectious disorders, such as cancers and other malignancies and their role in future medicine. Nanobiotechnology in Diagnosis, Drug Delivery and Treatment starts by introducing how nanotechnology has revolutionized drug delivery, diagnosis, and treatments of diseases. It then focuses on the role of various nanocomposites in diagnosis, drug delivery, and treatment of diseases like cancer, Alzheimer's disease, diabetes, and many others. Next, it discusses the application of a variety of nanomaterials in the diagnosis and management of gastrointestinal tract disorders. The book explains the concept of nanotheranostics in detail and its role in effective monitoring of drug response, targeted drug delivery, enhanced drug accumulation in the target tissues, sustained as well as triggered release of drugs, and reduction in adverse effects. Other chapters cover aptamer-incorporated nanoparticle systems; magnetic nanoparticles; theranostics and vaccines; toxicological concerns of nanomaterials used in nanomedicine; and more. Provides a concise overview of state-of-the-art nanomaterials and their application like drug delivery in infectious diseases and non-infectious disorders Highlights recent advances in the nano-based drug delivery systems and role of various nanomaterials Introduces nano-based sensors which detect various pathogens Covers the use of nanodevices in diagnostics and theranostics Nanobiotechnology in Diagnosis, Drug Delivery and Treatment is an ideal book for researchers and scientists working in various disciplines such as microbiology, biotechnology, nanotechnology, pharmaceutical biotechnology, pharmacology, pharmaceutics, and nanomedicine.

Nanotechnology and Cancer Treatment

Nanotechnology and Cancer Treatment Book
Author : Mohammadreza Saboktakin
Publisher : LAP Lambert Academic Publishing
Release : 2015-09-11
ISBN : 9783659780950
Language : En, Es, Fr & De

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Book Description :

The NanoBMat company, GmbH is a nanotechnology research center. The main activity fields of this company are the study of novel nanoparticles, nanomaterials and nanocomposites for industrial different applications such as pharmacy, medical, aerotechnology, textile, food, ...., the study of novel drug delivery systems for intelligent cancer therapy. such as photodynamic therapy method and the study of novel conductive and superparamagnetic nanocomposites for aero- and pharmaceutical applications

Pharmaceutical Nanotechnology

Pharmaceutical Nanotechnology Book
Author : Jean Cornier
Publisher : John Wiley & Sons
Release : 2017-02-06
ISBN : 3527340548
Language : En, Es, Fr & De

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Book Description :

With its focus on concrete methods and recent advances in applying nanotechnology to develop new drug therapies and medical diagnostics, this book provides an overall picture of the field, from the fundamentals of nanopharmacy with the characterisation and manufacturing methods to the role of nanoparticles and substances. Actual examples of utilization include drug development issues, translation to the clinic, market prospects, and industrial commercialization aspects. The applications described are taken from cancer treatment as well as other major therapeutic areas, such as infectious diseases and dermatology. An in-depth discussion on safety, regulatory, and societal aspects rounds off the book. Written by a top team of editors and authors composed of the leading experts in Europe and the USA who have pioneered the field of nanopharmacy!

Nanotechnology in Regenerative Medicine and Drug Delivery Therapy

Nanotechnology in Regenerative Medicine and Drug Delivery Therapy Book
Author : Haiyan Xu,Ning Gu
Publisher : Springer Nature
Release : 2020-07-21
ISBN : 9811553866
Language : En, Es, Fr & De

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Book Description :

The book focuses on the application of nanotechnologies in scaffold-guided tissue regeneration and in drug delivery systems for use in immunotherapy and overcoming drug resistance in cancer treatment. It covers a variety of topics, including nanomaterials for immunomodulation and immnunotherapy; molecular studies on self-assembly for peptides and DNA and related applications in tumor diagnosis and therapeutics and against human pathogenic bacteria; magnetic and conductive scaffolds for guiding tissue regeneration; multiple functions of magnetic nanoparticles in drug delivery and regenerative medicine; and re-purposing of traditional medicine in nano-formulations. In addition, it discusses common effects of nanomaterials, including reactive oxygen species and protein corona. Providing valuable insights and the presenting the latest research advances, the book allows readers to gain a systematic understanding of the topic.

Handbook of Nanotechnology Applications

Handbook of Nanotechnology Applications Book
Author : Kajornsak Faungnawakij,Woei Jye Lau,Uracha Rungsardthong Ruktanonchai,Kuakoon Piyachomkwan
Publisher : Elsevier
Release : 2020-10-22
ISBN : 0128215097
Language : En, Es, Fr & De

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Book Description :

Handbook of Nanotechnology Applications: Environment, Energy, Agriculture and Medicine presents a comprehensive overview on recent developments and prospects surrounding nanotechnology use in water/wastewater separation and purification, energy storage and conversion, agricultural and food process, and effective diagnoses and treatments in medical fields. The book includes detailed overviews of nanotechnology, including nanofiltration membrane for water/wastewater treatment, nanomedicine and nanosensor development for medical implementation, advanced nanomaterials of different structural dimensions (0D, 1D, 2D and 3D) for energy applications, as well as food and agricultural utilization. Other sections discuss the challenges of lab-based research transitioning towards practical industrial use. Helps scientists and researchers quickly learn and understand the key role of nanotechnology in important industrial applications Takes an interdisciplinary approach, demonstrating how nanotechnology is being used in a wide range of industry sectors Outlines the role nanotechnology plays in creating safer, cheaper and more energy-efficient projects and devices