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Nanostructures For Drug Delivery

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Nanostructures for Drug Delivery

Nanostructures for Drug Delivery Book
Author : Ecaterina Andronescu,Alexandru Mihai Grumezescu
Publisher : Elsevier
Release : 2017-03-24
ISBN : 0323461492
Language : En, Es, Fr & De

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Book Description :

Nanostructures for Drug Delivery extensively covers the various nanostructured products that have been tested as carriers in target drug delivery systems. In addition, the book analyses the advantages of, and issues related to, using nanostructured materials in drug delivery systems, also detailing various nanocarrier preparation techniques. As delivering the drug to the target site is a major problem in providing effective treatment for many diseases, this book covers the latest advancements in numerous nanotechnological products that are being used in disease detection, controlled drug delivery, as biosensors, and in tissue engineering that have been developed for more efficient patient healthcare. Due to the versatility of nanostructured materials, it is now possible to deliver a drug at its target site in a more accurate and efficient way. This volume is an up-to-date, state-of-the-art work that highlights the principal mechanistic aspects related to the delivery of active nanoscale therapeutic agents (natural or synthetic) and their release profile in different environmental media. It highlights nanoscale encapsulation strategies and discusses both organic and inorganic nanomaterials as carriers and delivery platforms. Demonstrates how nanostructures are successfully employed in drug delivery stems and as drug delivery agents, allowing biomaterials scientists and biochemists to create more effective drug delivery systems Offers an overview of recent research into the use of nanostructures in drug delivery techniques in a cogent, synthesized way, allowing readers to quickly familiarize themselves with this area Includes examples of how the application of nanostructures have improved the efficiency of drug delivery systems, showing medical scientists how they are beneficial

Core Shell Nanostructures for Drug Delivery and Theranostics

Core Shell Nanostructures for Drug Delivery and Theranostics Book
Author : Maria Focarete,Anna Tampieri
Publisher : Woodhead Publishing
Release : 2018-06-29
ISBN : 0081021992
Language : En, Es, Fr & De

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Book Description :

Core-Shell Nanostructures for Drug Delivery and Theranostics: Challenges, Strategies and Prospects for Novel Carrier Systems contains valuable chapters that deal with the fundamentals of nanotechnology for drug delivery, recent developments and research in core-shell nanoparticles for drug-delivery and theranostic applications, and the potential and applications of core-shell nanofiber. This book is a highly valuable resource for scientists interested in the design and development of innovative drug delivery systems, researchers and graduate/postdoctoral students engaged in biomaterials for drug delivery, and R&D managers in the biomaterials and pharmaceutical industry. Focuses on core-shell nanoparticles and nanofiber for innovative applications, including cancer therapy, controlled release and multi-drug release Considers future prospects and potential new applications of core-shell nanostructures for drug delivery and theranostics Explains the principles and essential concepts of nanotechnology for drug delivery systems

Functional Nanostructures for Sensors Optoelectronic Devices and Drug Delivery

Functional Nanostructures for Sensors  Optoelectronic Devices and Drug Delivery Book
Author : Maria Angela Castriciano
Publisher : MDPI
Release : 2020-12-04
ISBN : 3039432168
Language : En, Es, Fr & De

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Book Description :

Nanoparticles and nanostructured materials represent an active area of research and impact in many application fields. The recent progress obtained in the synthesis of nanomaterials, and the fundamental understanding of their properties, has driven significant advances for their technological applications. The Special Issue “Functional Nanostructures for Sensors, Optoelectronic Devices and Drug Delivery” aims to provide an overview of the current research activities in the field of nanostructured materials with a particular emphasis on their potential applications for sensors, optoelectronic devices and biomedical systems. The Special Issue includes submission of original research articles and comprehensive reviews that demonstrated or summarized significant advances in the above-mentioned research fields. The Special Issue is made up of fifteen original research articles and three comprehensive reviews covering various topics of nanostructured materials and relative characterization from fundamental research to technological applications. More than 100 scientists from universities and research institutions lent their expertize and shared their research activities to ensure the success of this Special Issue.

ZnO Nanostructures for Tissue Regeneration Drug Delivery and Theranostics Applications

ZnO Nanostructures for Tissue Regeneration  Drug Delivery and Theranostics Applications Book
Author : Valentina Cauda,Marco Laurenti
Publisher : MDPI
Release : 2021-03-25
ISBN : 303650656X
Language : En, Es, Fr & De

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Book Description :

Nanostructured zinc oxide materials are capturing a great deal of interest thanks to their outstanding and multifunctional properties, enabling broad series of intervention in the field of nanomedicine. ZnO can be easily prepared in a broad variety of shapes and shows anticancer and antimicrobial properties that are of interest for tissue engineering, controlled delivery of therapeutics, and even theranostics. This book is thus dedicated to the most recent advances in the field, presented as a collection of research papers and reviews. It spans from the synthesis and characterization of ZnO nanomaterials to their applications in the nanomedicine field, ranging from anticancer nanotherapeutics to dental implants and antibacterial agents.

Nanostructures for Oral Medicine

Nanostructures for Oral Medicine Book
Author : Ecaterina Andronescu,Alexandru Mihai Grumezescu
Publisher : Elsevier
Release : 2017-04-11
ISBN : 0323477216
Language : En, Es, Fr & De

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Book Description :

Nanostructures for Oral Medicine presents an up-to-date examination of the applications and effects of nanostructured materials in oral medicine, with each chapter addressing recent developments, specific applications, and uses of nanostructures in the oral administration of therapeutic agents in dentistry. The book also includes coverage of the biocompatibility of nanobiomaterials and their remarkable potential in improving human health and in reducing environmental pollution. Emerging advances, such as Dr. Franklin Tay's concept of a new nanotechnology process of growing extremely small, mineral-rich crystals and guiding them into the demineralized gaps between collagen fibers to prevent the aging and degradation of resin-dentin bonding is also discussed. This work will be of great value to those who work in oral medicine, providing them with a resource to gain a greater understanding of how nanotechnology can help them create more efficient, cost-effective products. In addition, it will be of great interest to those who work in materials science who wish to gain a greater appreciation of how nanostructured materials are applied in this field. Outlines the major uses of nanostructured materials for oral medicine, including the properties of each material discussed and how it should best be applied Explores how nanostructured materials enable the creation of more effective drug delivery systems in oral medicine Discusses how novel uses of nanostructured materials may be applied in oral medicine to create more effective devices

Materials for Biomedical Engineering Nanomaterials based Drug Delivery

Materials for Biomedical Engineering  Nanomaterials based Drug Delivery Book
Author : Alina-Maria Holban,Alexandru Grumezescu
Publisher : Elsevier
Release : 2019-03-20
ISBN : 0128169141
Language : En, Es, Fr & De

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Book Description :

Materials for Biomedical Engineering: Nanomaterials-Based Drug Delivery highlights the progress made in the field of nanostructures bioactive materials and their impact on efficient drug delivery towards personalized medicine. Drug delivery is a well investigated and challenging bio-medical field, with promising perspectives in medicine and engineering. This book brings together the latest research findings regarding nanostructured materials and their potential in designing highly efficient and personalized drug delivery systems. Provides a valuable resource of recent scientific progress, highlighting the most well-known applications of nanostructures in drug delivery systems Includes novel opportunities and ideas for developing or improving technologies in composites by companies, biomedical industries, and in related sectors Features at least 50% of references from the last 2-3 years

Biomedical Nanostructures

Biomedical Nanostructures Book
Author : Kenneth Gonsalves,Craig Halberstadt,Cato T. Laurencin,Lakshmi Nair
Publisher : John Wiley & Sons
Release : 2007-11-09
ISBN : 0470185821
Language : En, Es, Fr & De

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Book Description :

Learn to Use Nanoscale Materials to Design Novel Biomedical Devices and Applications Discover how to take full advantage of nanoscale materials in the design and fabrication of leading-edge biomedical devices. The authors introduce you to a variety of possible clinical applications such as drug delivery, diagnostics, and cancer therapy. In addition, the authors explore the interface between micron and nanoscale materials for the development of applications such as tissue engineering. Finally, they examine the mechanisms of cell interactions with material surfaces through the use of nanotechnology-based material processing and characterization methods. The text's three sections highlight its interdisciplinary approach: * Part One: Nanostructure Fabrication * Part Two: Bio-Nano Interfaces * Part Three: Clinical Applications of Nanostructures Among the key topics covered are nanotechnology in tissue regeneration; biomolecular engineering; receptor-ligand interactions; cell-biomaterial interactions; nanomaterials in diagnostics, drug delivery, and cancer therapy; and nano- and micron-level engineering and fabrication. Throughout the text, clear examples guide you through the chemistry and the processing involved in designing and developing nanoscale materials for biomedical devices. Each chapter begins with an introduction and ends with a conclusion highlighting the key points. In addition, references at the end of the chapter help you expand your research on any individual topic. In summary, this book helps biomedical researchers and engineers understand the physical phenomena that occur at the nanoscale in order to design novel cell-based constructs for a wide range of applications.

Nanomaterials in Drug Delivery Imaging and Tissue Engineering

Nanomaterials in Drug Delivery  Imaging  and Tissue Engineering Book
Author : Ashutosh Tiwari,Atul Tiwari
Publisher : John Wiley & Sons
Release : 2013-02-19
ISBN : 1118644743
Language : En, Es, Fr & De

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Book Description :

This groundbreaking, multidisciplinary work is one of the first books to cover Nanotheragnostics, the new developmental edge of nanomedicine. Through a collection of authoritative chapters, the book reports on nanoscopic therapeutic systems that incorporate therapeutic agents, molecular targeting, and diagnostic imaging capabilities. An invaluable reference for researchers in materials science, bioengineering, pharmacy, biotechnology, and nanotechnology, this volume features four main parts on biomedical nanomaterials, advanced nanomedicine, nanotheragnostics, and nanoscaffolds technology.

Design of Nanostructures for Versatile Therapeutic Applications

Design of Nanostructures for Versatile Therapeutic Applications Book
Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Release : 2018-02-03
ISBN : 0128136685
Language : En, Es, Fr & De

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Book Description :

Design of Nanostructures for Versatile Therapeutic Applications focuses on antimicrobial, antioxidant and nutraceutical applications of nanostructured materials. Many books discuss these subjects, but not from a pharmaceutical point-of-view. This book covers novel approaches related to the modulation of microbial biofilms, antimicrobial therapy and encapsulate polyphenols as antioxidants. Written by an internationally diverse group of academics, this book is an important reference resource for researchers, both in biomaterials science and the pharmaceutical industry. Assesses the most recently developed nanostructures that have potential antimicrobial properties, explaining their novel mechanical aspects Shows how nanoantibiotics can be used to more effectively treat disease Provides a cogent summary of recent developments in nanoantimicrobial discovery, allowing readers to quickly familiarize themselves with the topic

Drug Delivery Approaches and Nanosystems Volume 1

Drug Delivery Approaches and Nanosystems  Volume 1 Book
Author : Raj K. Keservani,Anil K. Sharma,Rajesh K. Kesharwani
Publisher : CRC Press
Release : 2017-11-15
ISBN : 1351846698
Language : En, Es, Fr & De

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Book Description :

This volume, the first of the two-volume Drug Delivery Approaches and Nanosystems series, presents a full picture of the state-of-the-art research and development in drug delivery systems using nanotechnology and its applications. It addresses the ever-expanding application of nanotechnology or nano-sized materials in the medical field and the real-world challenges and complexities of current drug delivery methodologies and techniques. Many methods of drug delivery systems have been used, but very few of them have been validated for medical use. A major reason for the above situation, the editors believe, is the gap between academia and research, and the gap between academic research and real-time clinical applications and needs. This volume addresses that gap. This volume presents 12 chapters that provide information about the preparation and characterization of nanocomposite materials used in drug delivery systems; advanced research of carbon nanotubes, nanocomposite materials, and polymer-clay, ceramics, and silicate glass-based nanocomposites; and the functionality of graphene nanocomposites. The book also provides detailed information on the application of nanotechnology in drug delivery systems in health care systems and medicine. The book describes how nanostructures are synthesized and draws attention to wide variety of nanostructures available for biological research and treatment applications. This valuable volume provides a wealth of information that will be valuable to scientists and researchers, faculty, and students. Volume 2 of the two-volume series is subtitled Drug Targeting Aspects of Nanotechnology. The volumes are available separately or as a set.

Chitosan Based Nanostructures

Chitosan Based Nanostructures Book
Author : Faisal A. Bughdadi,Abdel-Aziz S. El-Ahl,Adel Emara
Publisher : LAP Lambert Academic Publishing
Release : 2013
ISBN : 9783659342127
Language : En, Es, Fr & De

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Book Description :

This book highlighted the use of chitosan nanostructures in drug delivery, which facilitate the ability of the drug to cross the biological barriers. Chitosan has the desired properties for safe use as a pharmaceutical excipient. This has prompted accelerated research activities worldwide on chitosan nanoparticles as drug delivery vehicles. These systems have great utility in controlled release and targeting studies of almost all class of bioactive molecules as discussed in this book. Recently, chitosan is also extensively explored in gene delivery. However, studies toward optimization of process parameters and scale up from the laboratory to pilot plant and then, to production level are yet to be undertaken. Majority of studies carried out so far are only in vitro conditions. More in vivo studies need to be carried out. Chemical modifications of chitosan are important to get the desired physicochemical properties such as solubility, hydrophilicity, etc. The published literature indicates that in the near future, chitosan-based particulate systems will have more commercial status in the market than in the past.

Photoresponsive Self assembled Nanomaterials for On demand Drug Delivery

Photoresponsive Self assembled Nanomaterials for On demand Drug Delivery Book
Author : Wye Khay Fong
Publisher : Unknown
Release : 2013
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

On-demand drug delivery systems have the potential to optimise drug delivery by allowing drug administration as required. Lipid-based liquid crystalline matrices (LC) are increasingly explored as a means of controlled release drug delivery due to their biocompatibility and ability to incorporate and control the release drugs of a wide ranging size and polarity. The rate at which drug is released is ultimately determined by the mesophase nanostructure. This inbuilt 'on-off' switch for drug release affords the opportunity to manipulate drug delivery by influencing lipid packing by e.g. changing temperature. The utilisation of advanced synchrotron SAXS has allowed for the understanding of mechanisms by which transformations between lipid self-assembled structures take place. Understanding these interactions is essential in the development of self-assembled matrices for many bioapplications.Light-activated drug delivery systems have potential to provide a selective and non-invasive approach to accessing tissues that are not amenable to direct treatment. This thesis presents LC matrices which have been rendered light responsive by incorporation of additives that alter lipid packing upon irradiation and the effect of manipulating nanostructure on the release of drug from these matrices. Two approaches have been taken:1. PhotothermalGold nanorods were incorporated into LC matrices and irradiation with near infrared laser light induced reversible thermotropic phase transitions via a photothermal effect.2. PhotochromicPhotochromic compounds that undergo isomerisation in response to irradiation were incorporated into liquid crystalline systems where UV light induced a steric disturbance in the liquid crystalline nanostructure.The potential of these optically addressable nanostructures as reversible 'on-demand' drug delivery systems will translate into novel treatments for diseases such as macular degeneration.

Nanostructured Polymer Composites for Biomedical Applications

Nanostructured Polymer Composites for Biomedical Applications Book
Author : Sarat Kumar Swain,Mohammad Jawaid
Publisher : Elsevier
Release : 2019-06-15
ISBN : 0128168927
Language : En, Es, Fr & De

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Book Description :

Nanostructured Polymer Composites for Biomedical Applications addresses the challenges researchers face regarding the creation of nanostructured polymer composites that not only have superior performance and mechanical properties, but also have acceptable biological function. This book discusses current efforts to meet this challenge by discussing the multidisciplinary nature of nanostructured polymer composite biomaterials from various fields, including materials science, polymer science, biomedical engineering and biomedicine. This compilation of existing knowledge will lead to the generation of new terminology and definitions across individual disciplines. As such, this book will help researchers and engineers develop new products and devices for use in effective medical treatment. Summarizes the most recent strategies to develop nanostructured polymer composite biomaterials for biomedicine Outlines the major preparation and characterization techniques for a range of polymer nanocomposites used in biomedicine Explores the design of new types of nanostructured polymer composites for applications in drug delivery, tissue engineering, gene therapy and bone replacement

Smart Materials for Drug Delivery

Smart Materials for Drug Delivery Book
Author : Carmen Alvarez-Lorenzo,Angel Concheiro,Hans-Jorg Schneider,Mohsen Shahinpoor
Publisher : Royal Society of Chemistry
Release : 2013
ISBN : 1849738785
Language : En, Es, Fr & De

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Book Description :

Smart materials, which can change properties when an external stimulus is applied, can be used for the targeted drug delivery of an active molecule to a specific site in the correct dosage. Different materials such as liposomes, polymeric systems, nanomaterials and hydrogels can respond to different stimuli such as pH, temperature and light and these are all attractive for controlled release applications. With so many papers available on smart and stimuli-responsive materials for drug delivery applications it's hard to know where to start reading about this exciting topic. Smart Materials for Drug Delivery brings together the recent findings in the area and provides a critical analysis of the different materials available and how they can be applied to advanced drug delivery systems. With contributions from leading experts in the field, including a foreword from distinguished scientist Nicholas Peppas, The University of Texas at Austin, USA, the book will provide both an introduction to the key areas for graduate students and new researchers in the stimuli-responsive field as well as serving as a reference for those already working on fundamental materials research or drug delivery applications.

Self Organizing Nanovectors for Drug Delivery

Self Organizing Nanovectors for Drug Delivery Book
Author : Giuseppe De Rosa,Pietro Matricardi
Publisher : MDPI
Release : 2020-04-17
ISBN : 3039284282
Language : En, Es, Fr & De

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Book Description :

Nanomedicine represents one of the most investigated areas in the last two decades in the field of pharmaceutics. Several nanovectors have been developed and a growing number of products have been approved. It is well known that many biomaterials are able to self-organize under controlled conditions giving rise nanostructures. Polymers, lipids, inorganic materials, peptides and proteins, and surfactants are examples of such biomaterials and the self-assembling property can be exploited to design nanovectors that are useful for drug delivery. The self-organization of nanostructures is an attractive approach to preparing nanovectors, avoiding complex and high-energy-consuming preparation methods, and, in some cases, facilitating drug loading procedures. Moreover, preparations based on these biocompatible and pharmaceutical grade biomaterials allow an easy transfer from the lab to the industrial scale. This book reports ten different works, and a review, aiming to cover multiple strategies and pharmaceutical applications in the field of self-organizing nanovectors for drug delivery.

Pharmaceutical Nanotechnology

Pharmaceutical Nanotechnology Book
Author : Jean Cornier,Andrew Owen,Arno Kwade,Marcel Van de Voorde
Publisher : John Wiley & Sons
Release : 2016-11-28
ISBN : 3527800670
Language : En, Es, Fr & De

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Book Description :

With its focus on concrete methods and recent advances in applying nanotechnology to develop new drug therapies and medical diagnostics, this book provides an overall picture of the field, from the fundamentals of nanopharmacy with the characterisation and manufacturing methods to the role of nanoparticles and substances. Actual examples of utilization include drug development issues, translation to the clinic, market prospects, and industrial commercialization aspects. The applications described are taken from cancer treatment as well as other major therapeutic areas, such as infectious diseases and dermatology. An in-depth discussion on safety, regulatory, and societal aspects rounds off the book. Written by a top team of editors and authors composed of the leading experts in Europe and the USA who have pioneered the field of nanopharmacy!

Advanced Theranostic Materials

Advanced Theranostic Materials Book
Author : Ashutosh Tiwari,Hirak K. Patra,Jeong-Woo Choi
Publisher : John Wiley & Sons
Release : 2015-06-30
ISBN : 111899891X
Language : En, Es, Fr & De

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Book Description :

The present book is covers the recent advances in the development on the regulation of such theragnosis system and their biomedical perspectives to act as a future nanomedicine. Advanced Theranostics Materialsis written by a distinguished group of contributors and provides comprehensive coverage of the current literature, up-to-date overview of all aspects of advanced theranostics materials ranging from system biology, diagnostics, imaging, image-guided therapy, therapeutics, biosensors, and translational medicine and personalized medicine, as well as the much broader task of covering most topics of biomedical research. The books focusses on the following topics: Part 1: System biology and translational medicine Aberrant Signaling Pathways: Hallmark of Cancer Cells and Target for Nanotherapeutics Application of Nanoparticles in Cancer Treatment Biomacromolecule-Gated Mesoporous Silica Drug Delivery Systems Construction of Functional DNA Nanostructures for Theranostic Applications Smart Polypeptide Nanocarriers for Malignancy Therapeutics Part 2: Imaging and therapeutics Dimercaptosuccinic acid-coated magnetic nanoparticles as a localized delivery system in cancer immunotherapy Cardiovascular nanomedicine Chitosan-based systems for sustained drug release Nanocapsules in biomedicine: promises and challenges Chitosan-based polyelectrolyte complexes: characteristics and application in formulation of particulate drug carriers Part 3: Diagnostics and featured prognostics Non-invasive Glucose Biosensors based on Nanomaterials Self/directed Assembly of Nanoparticles: A review on various approaches Ion exchangers – an open window for the development of advanced materials with pharmaceutical and medical applications New Titanium Alloys for Biomedical Applications

Nanoconjugate Nanocarriers for Drug Delivery

Nanoconjugate Nanocarriers for Drug Delivery Book
Author : Raj K. Keservani,Anil K. Sharma
Publisher : CRC Press
Release : 2018-09-03
ISBN : 135117102X
Language : En, Es, Fr & De

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Book Description :

This new volume presents a plethora of new research on the use of nanoconjugate nanocarriers in drug delivery. Nanotechnology as drug carriers has been observed to increase the level of sophistication through a variety of ways. It helps to alleviate some of the pitfalls of conventional dosage forms, such as few pitfalls such as non-specific drug delivery, dose dumping, poor patient compliance, toxicities linked with higher doses, etc. With chapters from highly skilled, experienced, and renowned scientists and researchers, Nanoconjugate Nanocarriers for Drug Delivery is divided into four sections, providing an introduction to nanocarriers for drug delivery, physicochemical features of nanocarriers, and specific applications dealing with drug delivery in particular. The materials used as well as formulation and characterization have been discussed in detail. The nanocarriers covered in the book include nanoparticles, vesicular carriers, carriers having carbon as the core constituent, dispersed systems, etc. The book also delves into the interaction and associations between drug delivery research and its therapeutic applications in practice. The book integrates a wide variety of case studies, research, and theories in an attempt to reveal the diversity and capture the novel approaches of nanoconjugate nanocarriers for drug delivery employed by developers and content experts in the field. This timely publication will be an essential reference and current awareness source, building on the available literature in the field of pharmacy and biomedical science, while also providing ideas for further research opportunities in this dynamic field.

Pharmaceutical Nanotechnology

Pharmaceutical Nanotechnology Book
Author : Jean Cornier,Andrew Owen,Arno Kwade,Marcel Van de Voorde
Publisher : John Wiley & Sons
Release : 2016-11-28
ISBN : 3527800697
Language : En, Es, Fr & De

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Book Description :

With its focus on concrete methods and recent advances in applying nanotechnology to develop new drug therapies and medical diagnostics, this book provides an overall picture of the field, from the fundamentals of nanopharmacy with the characterisation and manufacturing methods to the role of nanoparticles and substances. Actual examples of utilization include drug development issues, translation to the clinic, market prospects, and industrial commercialization aspects. The applications described are taken from cancer treatment as well as other major therapeutic areas, such as infectious diseases and dermatology. An in-depth discussion on safety, regulatory, and societal aspects rounds off the book. Written by a top team of editors and authors composed of the leading experts in Europe and the USA who have pioneered the field of nanopharmacy!