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Nanostructures For Drug Delivery

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Core Shell Nanostructures for Drug Delivery and Theranostics

Core Shell Nanostructures for Drug Delivery and Theranostics Book
Author : Maria Focarete,Anna Tampieri
Publisher : Woodhead Publishing
Release : 2018-06-29
ISBN : 0081021992
Language : En, Es, Fr & De

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Book Description :

Core-Shell Nanostructures for Drug Delivery and Theranostics: Challenges, Strategies and Prospects for Novel Carrier Systems contains valuable chapters that deal with the fundamentals of nanotechnology for drug delivery, recent developments and research in core-shell nanoparticles for drug-delivery and theranostic applications, and the potential and applications of core-shell nanofiber. This book is a highly valuable resource for scientists interested in the design and development of innovative drug delivery systems, researchers and graduate/postdoctoral students engaged in biomaterials for drug delivery, and R&D managers in the biomaterials and pharmaceutical industry. Focuses on core-shell nanoparticles and nanofiber for innovative applications, including cancer therapy, controlled release and multi-drug release Considers future prospects and potential new applications of core-shell nanostructures for drug delivery and theranostics Explains the principles and essential concepts of nanotechnology for drug delivery systems

Nanostructures for Drug Delivery

Nanostructures for Drug Delivery Book
Author : Ecaterina Andronescu,Alexandru Mihai Grumezescu
Publisher : Elsevier
Release : 2017-03-24
ISBN : 0323461492
Language : En, Es, Fr & De

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Book Description :

Nanostructures for Drug Delivery extensively covers the various nanostructured products that have been tested as carriers in target drug delivery systems. In addition, the book analyses the advantages of, and issues related to, using nanostructured materials in drug delivery systems, also detailing various nanocarrier preparation techniques. As delivering the drug to the target site is a major problem in providing effective treatment for many diseases, this book covers the latest advancements in numerous nanotechnological products that are being used in disease detection, controlled drug delivery, as biosensors, and in tissue engineering that have been developed for more efficient patient healthcare. Due to the versatility of nanostructured materials, it is now possible to deliver a drug at its target site in a more accurate and efficient way. This volume is an up-to-date, state-of-the-art work that highlights the principal mechanistic aspects related to the delivery of active nanoscale therapeutic agents (natural or synthetic) and their release profile in different environmental media. It highlights nanoscale encapsulation strategies and discusses both organic and inorganic nanomaterials as carriers and delivery platforms. Demonstrates how nanostructures are successfully employed in drug delivery stems and as drug delivery agents, allowing biomaterials scientists and biochemists to create more effective drug delivery systems Offers an overview of recent research into the use of nanostructures in drug delivery techniques in a cogent, synthesized way, allowing readers to quickly familiarize themselves with this area Includes examples of how the application of nanostructures have improved the efficiency of drug delivery systems, showing medical scientists how they are beneficial

ZnO Nanostructures for Tissue Regeneration Drug Delivery and Theranostics Applications

ZnO Nanostructures for Tissue Regeneration  Drug Delivery and Theranostics Applications Book
Author : Valentina Cauda,Marco Laurenti
Publisher : MDPI
Release : 2021-03-25
ISBN : 303650656X
Language : En, Es, Fr & De

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Book Description :

Nanostructured zinc oxide materials are capturing a great deal of interest thanks to their outstanding and multifunctional properties, enabling broad series of intervention in the field of nanomedicine. ZnO can be easily prepared in a broad variety of shapes and shows anticancer and antimicrobial properties that are of interest for tissue engineering, controlled delivery of therapeutics, and even theranostics. This book is thus dedicated to the most recent advances in the field, presented as a collection of research papers and reviews. It spans from the synthesis and characterization of ZnO nanomaterials to their applications in the nanomedicine field, ranging from anticancer nanotherapeutics to dental implants and antibacterial agents.

Nanoconjugate Nanocarriers for Drug Delivery

Nanoconjugate Nanocarriers for Drug Delivery Book
Author : Raj K. Keservani,Anil K. Sharma
Publisher : CRC Press
Release : 2018-09-03
ISBN : 135117102X
Language : En, Es, Fr & De

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Book Description :

This new volume presents a plethora of new research on the use of nanoconjugate nanocarriers in drug delivery. Nanotechnology as drug carriers has been observed to increase the level of sophistication through a variety of ways. It helps to alleviate some of the pitfalls of conventional dosage forms, such as few pitfalls such as non-specific drug delivery, dose dumping, poor patient compliance, toxicities linked with higher doses, etc. With chapters from highly skilled, experienced, and renowned scientists and researchers, Nanoconjugate Nanocarriers for Drug Delivery is divided into four sections, providing an introduction to nanocarriers for drug delivery, physicochemical features of nanocarriers, and specific applications dealing with drug delivery in particular. The materials used as well as formulation and characterization have been discussed in detail. The nanocarriers covered in the book include nanoparticles, vesicular carriers, carriers having carbon as the core constituent, dispersed systems, etc. The book also delves into the interaction and associations between drug delivery research and its therapeutic applications in practice. The book integrates a wide variety of case studies, research, and theories in an attempt to reveal the diversity and capture the novel approaches of nanoconjugate nanocarriers for drug delivery employed by developers and content experts in the field. This timely publication will be an essential reference and current awareness source, building on the available literature in the field of pharmacy and biomedical science, while also providing ideas for further research opportunities in this dynamic field.

Surface Modification of Nanoparticles for Targeted Drug Delivery

Surface Modification of Nanoparticles for Targeted Drug Delivery Book
Author : Yashwant V Pathak
Publisher : Springer
Release : 2019-03-21
ISBN : 9783030061142
Language : En, Es, Fr & De

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Book Description :

This unique book is the only one to discuss various new techniques developed to enhance the application of nanoparticulate drug delivery systems using surface modification of nanoparticles. The understanding of the surface characteristics nano-particles is growing significantly with the advent of new analytical techniques. Polymer chemistry is contributing to the development of many new versatile polymers which have abilities to accommodate many different, very reactive chemical groups, and can be used as a diagnostic tool, for better targeting, for more effective therapeutic results as well as for reducing the toxic and side effects of the drugs. Surface modification of such polymeric nanoparticles has been found by many scientists to enhance the application of nanoparticles and also allows the nano particles to carry specific drug molecule and disease /tumor specific antibodies which refine and improve drug delivery. Surface Modification of Nanoparticles for Targeted Drug Delivery is a collection essential information with various applications of surface modification of nanoparticles and their disease specific applications for therapeutic purposes.

Nanomaterials in Drug Delivery Imaging and Tissue Engineering

Nanomaterials in Drug Delivery  Imaging  and Tissue Engineering Book
Author : Ashutosh Tiwari,Atul Tiwari
Publisher : John Wiley & Sons
Release : 2013-02-19
ISBN : 1118644743
Language : En, Es, Fr & De

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Book Description :

This groundbreaking, multidisciplinary work is one of the first books to cover Nanotheragnostics, the new developmental edge of nanomedicine. Through a collection of authoritative chapters, the book reports on nanoscopic therapeutic systems that incorporate therapeutic agents, molecular targeting, and diagnostic imaging capabilities. An invaluable reference for researchers in materials science, bioengineering, pharmacy, biotechnology, and nanotechnology, this volume features four main parts on biomedical nanomaterials, advanced nanomedicine, nanotheragnostics, and nanoscaffolds technology.

Functional Nanostructures for Sensors Optoelectronic Devices and Drug Delivery

Functional Nanostructures for Sensors  Optoelectronic Devices and Drug Delivery Book
Author : Maria Angela Castriciano
Publisher : MDPI
Release : 2020-12-04
ISBN : 3039432168
Language : En, Es, Fr & De

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Book Description :

Nanoparticles and nanostructured materials represent an active area of research and impact in many application fields. The recent progress obtained in the synthesis of nanomaterials, and the fundamental understanding of their properties, has driven significant advances for their technological applications. The Special Issue “Functional Nanostructures for Sensors, Optoelectronic Devices and Drug Delivery” aims to provide an overview of the current research activities in the field of nanostructured materials with a particular emphasis on their potential applications for sensors, optoelectronic devices and biomedical systems. The Special Issue includes submission of original research articles and comprehensive reviews that demonstrated or summarized significant advances in the above-mentioned research fields. The Special Issue is made up of fifteen original research articles and three comprehensive reviews covering various topics of nanostructured materials and relative characterization from fundamental research to technological applications. More than 100 scientists from universities and research institutions lent their expertize and shared their research activities to ensure the success of this Special Issue.

Nanostructures for Oral Medicine

Nanostructures for Oral Medicine Book
Author : Ecaterina Andronescu,Alexandru Mihai Grumezescu
Publisher : Elsevier
Release : 2017-04-11
ISBN : 0323477216
Language : En, Es, Fr & De

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Book Description :

Nanostructures for Oral Medicine presents an up-to-date examination of the applications and effects of nanostructured materials in oral medicine, with each chapter addressing recent developments, specific applications, and uses of nanostructures in the oral administration of therapeutic agents in dentistry. The book also includes coverage of the biocompatibility of nanobiomaterials and their remarkable potential in improving human health and in reducing environmental pollution. Emerging advances, such as Dr. Franklin Tay's concept of a new nanotechnology process of growing extremely small, mineral-rich crystals and guiding them into the demineralized gaps between collagen fibers to prevent the aging and degradation of resin-dentin bonding is also discussed. This work will be of great value to those who work in oral medicine, providing them with a resource to gain a greater understanding of how nanotechnology can help them create more efficient, cost-effective products. In addition, it will be of great interest to those who work in materials science who wish to gain a greater appreciation of how nanostructured materials are applied in this field. Outlines the major uses of nanostructured materials for oral medicine, including the properties of each material discussed and how it should best be applied Explores how nanostructured materials enable the creation of more effective drug delivery systems in oral medicine Discusses how novel uses of nanostructured materials may be applied in oral medicine to create more effective devices

Protein and Peptide Nanoparticles for Drug Delivery

Protein and Peptide Nanoparticles for Drug Delivery Book
Author : Rossen Donev
Publisher : Advances in Protein Chemistry
Release : 2015
ISBN : 9780128028285
Language : En, Es, Fr & De

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Book Description :

Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology series has been the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts in a broad range of protein-related topics. Describes advances in application of powerful techniques in a wide bioscience area Chapters are written by authorities in their field Targeted to a wide audience of researchers, specialists, and students The information provided in the volume is well supported by a number of high quality illustrations, figures, and tables

Development of Dual Functional DNA RNA Nanostructures for Drug Delivery

Development of Dual Functional DNA RNA Nanostructures for Drug Delivery Book
Author : Vibhav A. Valsangkar
Publisher : Unknown
Release : 2020
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Development of Dual Functional DNA RNA Nanostructures for Drug Delivery book written by Vibhav A. Valsangkar, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Nanoparticulate Drug Delivery Systems

Nanoparticulate Drug Delivery Systems Book
Author : Deepak Thassu,Michel Deleers,Yashwant Vishnupant Pathak,Yashwant Pathak
Publisher : CRC Press
Release : 2007-03-30
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

With the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. Nanoparticulate Drug Delivery Systems addresses the scientific methodologies, formulation, processing, applications, recent trends, and emerging technologies in the research of nanoparticulate drug delivery systems (NPDDS). It extensively covers applications of NPDDS— including lipid nanoparticles for dermal applications; nanocarriers for the treatment of restenosis; and for ocular, central nervous system, and gastrointestinal applications. It also explores its use as an adjuvant for vaccine development. Supplying insight from international experts, this guide Discusses formulation for poorly soluble drugs Presents biological requirements for nanotherapeutic applications Demonstrates the role of nanobiotechnology in the development of nanomedicine Documents recent advances in nanoparticulate technology—including electrospining, formation of microcrystals, and production of liquid crystalline phases Examines the technology of metallic nanoparticles

Engineering of Biomaterials for Drug Delivery Systems

Engineering of Biomaterials for Drug Delivery Systems Book
Author : Anilkumar Parambath
Publisher : Woodhead Publishing Limited
Release : 2018-01-27
ISBN : 9780081017500
Language : En, Es, Fr & De

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Book Description :

Engineering of Biomaterials for Drug Delivery Systems: Beyond Polyethylene Glycol examines the combined issues of PEGylation and viable biomaterials as alternatives. With a strong focus on polymeric biomaterials, the book first reviews the major issues associated with PEGylation and its use in vivo. Chapters then focus on alternative polymer systems for drug delivery systems. Finally, nanoparticles and future perspectives are examined. This book is a valuable resource for scientists and researchers in biomaterials, pharmaceuticals and nanotechnology, and all those who wish to broaden their knowledge in this field. Provides a self-contained work for the field of biomaterials for drug delivery Summarizes the current knowledge on PEGylation and strategies for bypassing it Presents research on an important, though under-represented issue in biomaterials Written by a world-class team of research scientists, engineers and clinicians

Advanced Theranostic Materials

Advanced Theranostic Materials Book
Author : Ashutosh Tiwari,Hirak K. Patra,Jeong-Woo Choi
Publisher : John Wiley & Sons
Release : 2015-06-30
ISBN : 111899891X
Language : En, Es, Fr & De

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Book Description :

The present book is covers the recent advances in the development on the regulation of such theragnosis system and their biomedical perspectives to act as a future nanomedicine. Advanced Theranostics Materialsis written by a distinguished group of contributors and provides comprehensive coverage of the current literature, up-to-date overview of all aspects of advanced theranostics materials ranging from system biology, diagnostics, imaging, image-guided therapy, therapeutics, biosensors, and translational medicine and personalized medicine, as well as the much broader task of covering most topics of biomedical research. The books focusses on the following topics: Part 1: System biology and translational medicine Aberrant Signaling Pathways: Hallmark of Cancer Cells and Target for Nanotherapeutics Application of Nanoparticles in Cancer Treatment Biomacromolecule-Gated Mesoporous Silica Drug Delivery Systems Construction of Functional DNA Nanostructures for Theranostic Applications Smart Polypeptide Nanocarriers for Malignancy Therapeutics Part 2: Imaging and therapeutics Dimercaptosuccinic acid-coated magnetic nanoparticles as a localized delivery system in cancer immunotherapy Cardiovascular nanomedicine Chitosan-based systems for sustained drug release Nanocapsules in biomedicine: promises and challenges Chitosan-based polyelectrolyte complexes: characteristics and application in formulation of particulate drug carriers Part 3: Diagnostics and featured prognostics Non-invasive Glucose Biosensors based on Nanomaterials Self/directed Assembly of Nanoparticles: A review on various approaches Ion exchangers – an open window for the development of advanced materials with pharmaceutical and medical applications New Titanium Alloys for Biomedical Applications

Materials for Biomedical Engineering Nanomaterials based Drug Delivery

Materials for Biomedical Engineering  Nanomaterials based Drug Delivery Book
Author : Alina-Maria Holban,Alexandru Grumezescu
Publisher : Elsevier
Release : 2019-03-20
ISBN : 0128169141
Language : En, Es, Fr & De

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Book Description :

Materials for Biomedical Engineering: Nanomaterials-Based Drug Delivery highlights the progress made in the field of nanostructures bioactive materials and their impact on efficient drug delivery towards personalized medicine. Drug delivery is a well investigated and challenging bio-medical field, with promising perspectives in medicine and engineering. This book brings together the latest research findings regarding nanostructured materials and their potential in designing highly efficient and personalized drug delivery systems. Provides a valuable resource of recent scientific progress, highlighting the most well-known applications of nanostructures in drug delivery systems Includes novel opportunities and ideas for developing or improving technologies in composites by companies, biomedical industries, and in related sectors Features at least 50% of references from the last 2-3 years

Nanocarriers for Drug Delivery

Nanocarriers for Drug Delivery Book
Author : Shyam Mohapatra, MD,Shivendu Ranjan,Nandita Dasgupta,Raghvendra Kumar Mishra,Sabu Thomas
Publisher : Elsevier
Release : 2018-09-15
ISBN : 9780128140338
Language : En, Es, Fr & De

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Book Description :

Nano-carriers for Drug Delivery: Nanoscience and Nanotechnology in Drug Delivery presents recent discoveries in research on the pharmaceutical applications of the various types of nanosystem-based drug delivery systems. As many nanosystems have reached the market over the past decade, this book proves their benefits to patients. It explores these new carriers and the advances in drug delivery they have facilitated. Reflecting the interdisciplinary nature of the subject matter, the book includes experts from different fields, and with various backgrounds and expertise. It will appeal to researchers and students from different disciplines, such as materials science, technology and various biomedical fields. Coverage includes industrial applications that bridge the gap between lab-based research and practical industrial use. The resulting work is a reference and practical source of guidance for researchers, students and scientists working in the fields of nanotechnology, materials science and technology and biomedical science. Enables readers from different fields to access recent research and protocols across traditional boundaries Focuses on protocols and techniques, as well as the knowledge base of the field, thus enabling those in R&D to learn about, and successfully deploy, cutting-edge techniques Includes sections on nanocarrier systems

Smart Internal Stimulus Responsive Nanocarriers for Drug and Gene Delivery

Smart Internal Stimulus Responsive Nanocarriers for Drug and Gene Delivery Book
Author : Mahdi Karimi,Parham Sahandi Zangabad,Amir Ghasemi,Michael R Hamblin
Publisher : Morgan & Claypool Publishers
Release : 2015-12-01
ISBN : 1681742578
Language : En, Es, Fr & De

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Book Description :

The concept of smart drug delivery vehicles involves designing and preparing a nanostructure (or microstructure) that can be loaded with a cargo. This can be a therapeutic drug, a contrast agent for imaging, or a nucleic acid for gene therapy. The nanocarrier serves to protect the cargo from degradation by enzymes in the body, to enhance the solubility of insoluble drugs, to extend the circulation half-life, and to enhance its penetration and accumulation at the target site. Importantly, smart nanocarriers can be designed to be responsive to a specific stimulus, so that the cargo is only released or activated when desired. In this volume we cover smart nanocarriers that respond to internal stimuli that are intrinsic to the target site. These stimuli are specific to the cell type, tissue or organ type, or to the disease state (cancer, infection, inflammation etc). pH-responsive nanostructures can be used for cargo release in acidic endosomal compartments, in the lower pH of tumors, and for specific oral delivery either to the stomach or intestine. Nanocarriers can be designed to be substrates of a wide-range of enzymes that are over-expressed at disease sites. Oxidation and reduction reactions can be taken advantage of in smart nanocarriers by judicious molecular design. Likewise, nanocarriers can be designed to respond to a range of specific biomolecules that may occur at the target site. In this volume we also cover dual and multi-responsive systems that combine stimuli that could be either internal or external.

Drug Delivery Approaches and Nanosystems Volume 2

Drug Delivery Approaches and Nanosystems  Volume 2 Book
Author : Raj K. Keservani,Anil K. Sharma
Publisher : Unknown
Release : 2017
ISBN : 9781771885843
Language : En, Es, Fr & De

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Book Description :

Cover -- Half Title -- Title Page -- Copyright Page -- Dedication -- Table of Contents -- List of Contributors -- List of Abbreviations -- Preface -- About the Editors -- 1: Drug Targeting: General Aspects and Relevance to Nanotechnology -- 2: Nano-Oncotargets and Innovative Therapies -- 3: Dendrimer Conjugates as Novel DNA and siRNA Carriers -- 4: Precise Preparation of Functional Polysaccharides Nanoparticles by an Enzymatic Approach -- 5: Polysaccharide-Drug Nanoconjugates as Targeted Delivery Vehicles -- 6: Glycan-Based Nanocarriers in Drug Delivery -- 7: Physiological and Clinical Considerations of Drug Delivery Systems Containing Carbon Nanotubes and Graphene -- 8: Nanofibers: General Aspects and Applications -- 9: Nanocomposite Microparticles (nCmP) for Pulmonary Drug Delivery Applications -- 10: Solid Lipid Nanoparticles for Topical Drug Delivery -- 11: Hydrophobized Polymers for Encapsulation of Amphotericin B in Nanoparticles

Drug Delivery Nanosystems for Biomedical Applications

Drug Delivery Nanosystems for Biomedical Applications Book
Author : Chandra P Sharma
Publisher : Elsevier
Release : 2018-08-22
ISBN : 0323509231
Language : En, Es, Fr & De

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Book Description :

Drug Delivery Nanosystems for Biomedical Application reviews some of the most challenging nanosystems with different routes of delivery that are useful for specific drugs, from both efficacy and bioavailability points-of-view. The chapters explore how this area is developing, the present state of the field, and future developments, in particular, inorganic, metallic, polymeric, composite and lipid nanosystems and their possible evolution to clinical applications. The book is a valuable research reference for both researchers and industrial partners who are not only interested in learning about this area, but also want to gain insights on how to move towards translational research. Focuses on applications, including tissue engineering and regenerative technologies, showing how nanosystems are used in practice Explores how nanosystems are used to deliver a variety of drugs, including peptides, hormone growth factors and genes Assesses the safety and nanotoxicity aspects of drug delivery nanosystems

Smart External Stimulus Responsive Nanocarriers for Drug and Gene Delivery

Smart External Stimulus Responsive Nanocarriers for Drug and Gene Delivery Book
Author : Mahdi Karimi,Parham Sahandi Zangabad,Amir Ghasemi,Michael R Hamblin
Publisher : Morgan & Claypool Publishers
Release : 2015-12-01
ISBN : 1681742020
Language : En, Es, Fr & De

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Book Description :

The concept of smart drug delivery vehicles involves designing and preparing a nanostructure (or microstructure) that can be loaded with a cargo, this can be a therapeutic drug, a contrast agent for imaging, or a nucleic acid for gene therapy. The nanocarrier serves to protect the cargo from degradation by enzymes in the body, to enhance the solubility of insoluble drugs, to extend the circulation half-life, and to enhance its penetration and accumulation at the target site. Importantly, smart nanocarriers can be designed to be responsive to a specific stimulus, so that the cargo is only released or activated when desired. In this volume we cover smart nanocarriers that respond to externally applied stimuli that usually involve application of physical energy. This physical energy can be applied from outside the body and can either cause cargo release, or can activate the nanostructure to be cytotoxic, or both. The stimuli covered include light of various wavelengths (ultraviolet, visible or infrared), temperature (increased or decreased), magnetic fields (used to externally manipulate nanostructures and to activate them), ultrasound, and electrical and mechanical forces. Finally we discuss the issue of nanotoxicology and the future scope of the field.