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Nanostructures For Antimicrobial Therapy

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Nanostructures for Antimicrobial Therapy

Nanostructures for Antimicrobial Therapy Book
Author : Anton Ficai,Alexandru Mihai Grumezescu
Publisher : Elsevier
Release : 2017-05-29
ISBN : 0323461514
Language : En, Es, Fr & De

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Book Description :

Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. Shows how nanoantibiotics can be used to more effectively treat disease Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area

Antimicrobial Nanoarchitectonics

Antimicrobial Nanoarchitectonics Book
Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Release : 2017-06-22
ISBN : 0323527345
Language : En, Es, Fr & De

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Book Description :

Antimicrobial Nanoarchitectonics: From Synthesis to Applications brings together recent research in antimicrobial nanoparticles, specifically in the sustained and controlled delivery of antimicrobials. Particular attention is given to i) reducing the side effects of antibiotics, ii) increasing the pharmacological effect, and iii) improving aqueous solubility and chemical stability of different antimicrobials. In addition, antimicrobial nanoparticles in drug delivery are discussed extensively. The book also evaluates the pros and cons of using nanostructured biomaterials in the prevention and eradication of infections. It is an important reference resource for materials scientists and bioengineers who want to learn how nanomaterials are used in antimicrobial therapy. Provides readers with the information necessary to select the appropriate bionanomaterial to solve particular infection problems Includes case studies, showing how particular bionanomaterials have been used to cure infections Explains the central role that nanotechnology plays in modern antimicrobial therapy Evaluates the pros and cons of using nanostructured biomaterials in the prevention and eradication of infections

Nanostructures for Antimicrobial and Antibiofilm Applications

Nanostructures for Antimicrobial and Antibiofilm Applications Book
Author : Ram Prasad,Busi Siddhardha,Madhu Dyavaiah
Publisher : Springer Nature
Release : 2020-05-12
ISBN : 3030403378
Language : En, Es, Fr & De

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Book Description :

In the pursuit of technological advancement in the field of biotechnology and pharmaceutical industries to counteract health issues, bacterial infections remain a major cause of morbidity and mortality. The ability of bacterial pathogens to form biofilms further agglomerates the situation by showing resistance to conventional antibiotics. To overcome this serious issue, bioactive metabolites and other natural products were exploited to combat bacterial infections and biofilm-related health consequences. Natural products exhibited promising results in vitro, however; their efficacy in in vivo conditions remain obscured due to their low-solubility, bioavailability, and biocompatibility issues. In this scenario, nanotechnological interventions provide a multifaceted platform for targeted delivery of bioactive compounds by slow and sustained release of drug-like compounds. The unique physico-chemical properties, biocompatibility and eco-friendly nature of bioinspired nanostructures has revolutionized the field of biology to eradicate microbial infections and biofilm-related complications. The green-nanotechnology based metal and metal oxide nanoparticles and polymeric nanoparticles have been regularly employed for antimicrobial and antibiofilm applications without causing damage to host tissues. The implications of these nanoparticles toward achieving sustainability in agriculture by providing systemic resistance against a variety of phytopathogens therefore plays crucial role in growth and crop productivity. Also the advent of smart and hybrid nanomaterials such as metal-based polymer nanocomposites, lipid-based nanomaterials and liposomes have the inherent potential to eradicate bacterial biofilm-related infections in an efficient manner. The recent development of carbon-based nanomaterials such as carbon nanotubes (CNTs) and silica based nanomaterials such as mesoporous silica nanoparticles (MSNs) also exploit a target of dreadful healthcare conditions such as cancer, immunomodulatory diseases, and microbial infections, as well as biofilm-related issues owing to their stability profile, biocompatibility, and unique physio-chemical properties. Recently novel physical approaches such as photothermal therapy (PTT) and antimicrobial photodynamic therapy (aPDT) also revolutionized conventional strategies and are engaged in eradicating microbial biofilm-related infections and related health consequences. These promising advancements in the development of novel strategies to treat microbial infections and biofilm-related multidrug resistance (MDR) phenomenon may provide new avenues and aid to conventional antimicrobial therapeutics.

Nanotechnology in Diagnosis Treatment and Prophylaxis of Infectious Diseases

Nanotechnology in Diagnosis  Treatment and Prophylaxis of Infectious Diseases Book
Author : Mahendra Rai,Kateryna Kon
Publisher : Academic Press
Release : 2015-05-23
ISBN : 0128014717
Language : En, Es, Fr & De

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Book Description :

Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases delivers comprehensive coverage of the application of nanotechnology to pressing problems in infectious disease. This text equips readers with cutting-edge knowledge of promising developments and future prospects in nanotechnology, paying special attention to microbes that are now resistant to conventional antibiotics, a concerning problem in modern medicine. Readers will find a thorough discussion of this new approach to infectious disease treatment, including the reasons nanotechnology presents a promising avenue for the diagnosis, treatment, and prophylaxis of infectious diseases. Provides a comprehensive overview of the use of nanotechnology in the treatment and diagnosis of infectious diseases Covers all common types of infective agents, including bacteria, viruses, fungi, and protozoa, along with their vectors, ticks, mosquitoes, flies, etc. Delivers commentary from an international researcher base, providing insights across differing economic statuses Includes a foundation of basic nanotechnological concepts to aid in designing new strategies to combat several pathogenic diseases and cancer Illustrates the high antimicrobial potential of nanoparticles, ultimately demonstrating how they are a promising alternative class that can be successfully used in fighting a myriad of infections

Design of Nanostructures for Versatile Therapeutic Applications

Design of Nanostructures for Versatile Therapeutic Applications Book
Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Release : 2018-02-03
ISBN : 0128136685
Language : En, Es, Fr & De

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Book Description :

Design of Nanostructures for Versatile Therapeutic Applications focuses on antimicrobial, antioxidant and nutraceutical applications of nanostructured materials. Many books discuss these subjects, but not from a pharmaceutical point-of-view. This book covers novel approaches related to the modulation of microbial biofilms, antimicrobial therapy and encapsulate polyphenols as antioxidants. Written by an internationally diverse group of academics, this book is an important reference resource for researchers, both in biomaterials science and the pharmaceutical industry. Assesses the most recently developed nanostructures that have potential antimicrobial properties, explaining their novel mechanical aspects Shows how nanoantibiotics can be used to more effectively treat disease Provides a cogent summary of recent developments in nanoantimicrobial discovery, allowing readers to quickly familiarize themselves with the topic

Antibacterial Agents

Antibacterial Agents Book
Author : Ranjith Kumavath
Publisher : BoD – Books on Demand
Release : 2017-05-31
ISBN : 9535131990
Language : En, Es, Fr & De

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Book Description :

New drugs are frequently entering into the market along with the existing drugs. The antibacterial agents can be discussed in five major classes, i.e. classification based on the type of action, source, spectrum of activity, chemical structure and function. Resistance of bacteria to antibiotics is an urgent problem of the humanity, which leads us to the lack of therapy for serious bacterial infections. Development of new antibiotics has almost ceased in the last decades - even when a new antibiotic is launched, very soon the resistance of bacteria appears. Industrial textiles exposed as awnings, screens, tents; upholstery used in large public areas such as hospitals, hotels and stations; fabrics for transports; protective clothing and personal protective equipment; bed sheets and blankets; textiles left wet between processing steps; intimate apparel, underwear, socks and sportswear, disinfection of air and water for white rooms, hospitals and operating theatres, food and pharma industries, water depuration, drinkable water supplying and air conditioning systems. Many clinicians recommend alternative approaches to using antimicrobial substances. Moreover, the majority of bioagents demonstrate on antibiotics for treatment of a wide range of diseases in human sectors. However, the misuse and mishandling of drugs lead to microbial, particularly bacterial, resistance as well as result in the difficulty of treating microbial diseases. Hence, the proposed book will give more precise information on novel antibacterial compound(s).

Nanoscale Processing

Nanoscale Processing Book
Author : Sabu Thomas,Preetha Balakrishnan
Publisher : Elsevier
Release : 2020-10-22
ISBN : 0128205709
Language : En, Es, Fr & De

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Book Description :

Nanoscale Processing outlines recent advances in processing techniques for a range of nanomaterial types. New developments in the processing of nanostructured materials are being applied in diverse fields. This book offers in-depth information and analysis of a range of processing techniques for nanostructures, and also covers nanocharacterization aspects thoroughly. Topics covered include zero dimensional nanostructures, nanostructured biomaterials, carbon-based nanostructures, polymeric and liposomal nanostructures, and quantum dots. This book is an important resource for materials scientists and engineers looking to learn more about a variety of processing techniques for various nanomaterial classes, for use in both the industrial and biomedical sectors. Explains major nanoscale processing techniques, outlining in which situations each should be used Discuses a range of nanomaterial classes, including nanobiomaterials, polymeric nanomaterials, optical nanomaterials and magnetic nanomaterials Explores the challenges of using certain processing techniques for certain classes of nanomaterial

Nanostructures for Cancer Therapy

Nanostructures for Cancer Therapy Book
Author : Alexandru Mihai Grumezescu,Anton Ficai
Publisher : Elsevier
Release : 2017-04-11
ISBN : 0323461506
Language : En, Es, Fr & De

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Book Description :

Nanostructures for Cancer Therapy discusses the available preclinical and clinical nanoparticle technology platforms and their impact on cancer therapy, including current trends and developments in the use of nanostructured materials in chemotherapy and chemotherapeutics. In particular, coverage is given to the applications of gold nanoparticles and quantum dots in cancer therapies. In addition to the multifunctional nanomaterials involved in the treatment of cancer, other topics covered include nanocomposites that can target tumoral cells and the release of antitumoral therapeutic agents. The book is an up-to-date overview that covers the inorganic and organic nanostructures involved in the diagnostics and treatment of cancer. Provides an examination of nanoparticle delivery systems for cancer treatment, illustrating how the use of nanotechnology can help provide more effective chemotherapeutic treatments Examines, in detail, the different types of nanomaterials used in cancer therapy, also explaining the effect of each Provides a cogent overview of recent developments in the use of nanostructured materials in chemotherapeutics, allowing readers to quickly familiarize themselves with this area

Photomedicine

Photomedicine Book
Author : Yohei Tanaka
Publisher : BoD – Books on Demand
Release : 2017-05-17
ISBN : 9535131559
Language : En, Es, Fr & De

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Book Description :

Photomedicine is one of the most inspiring and interdisciplinary fields in medicine that involves the research and application of photobiology with respect to health and disease. Photomedicine has contributed to the clinical practice of a variety of medical fields, including dermatology, surgery, radiology, diagnostics, cardiology, and anticancer therapy. Furthermore, expansion of its scope and contribution can be expected. This book covers a wide range of aspects and issues related to photomedicine, which brings together researchers from many countries. These include the basic science of photodynamic therapy, clinical applications in various kinds of medical fields, photochemotherapy, laser therapy for musculoskeletal pain, intense pulsed light therapy for photorejuvenation, biological function of low-level laser therapy, and photobiology for skin rejuvenation. Not only will this be beneficial for readers, but it will also contribute to scientists making further breakthroughs in photomedicine.

Nanoparticles in Pharmacotherapy

Nanoparticles in Pharmacotherapy Book
Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Release : 2019-04-15
ISBN : 0128165049
Language : En, Es, Fr & De

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Book Description :

Nanoparticles in Pharmacotherapy explores the most recent findings in how nanoparticles used in pharmacotherapy, starting with their synthesis, characterization and current or potential uses. Offering he book will be a valuable resource of recent scientific progress, along with most known applications of nanoparticles on the pharmacotherapy to be used by researchers, medical doctors and academia individuals.

Advanced Nanostructured Materials for Environmental Remediation

Advanced Nanostructured Materials for Environmental Remediation Book
Author : Mu. Naushad,Saravanan Rajendran,Francisco Gracia
Publisher : Springer
Release : 2019-03-14
ISBN : 3030044777
Language : En, Es, Fr & De

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Book Description :

This book provides a wide-range exploration on the ongoing research and developmental events in environmental nanotechnology. Emerging nanomaterials and its technology have been known to offer unique advantages and are continually showing promising potential attracting continuous global attention. This work thus discusses experimental studies of various nanomaterials along with their design and applications and with specific attention to chemical reactions and their challenges for catalytic systems. It will make a noteworthy appeal to scientists and researchers working in the field of nanotechnology for environmental sciences.

Copper Nanostructures Next Generation of Agrochemicals for Sustainable Agroecosystems

Copper Nanostructures  Next Generation of Agrochemicals for Sustainable Agroecosystems Book
Author : Kamel A. Abd-Elsalam
Publisher : Elsevier
Release : 2022-01-13
ISBN : 0128241942
Language : En, Es, Fr & De

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Book Description :

Copper Nanostructures: Next-Generation of Agrochemicals for Sustainable Agroecosystems considers the impact of copper-based nanostructures on agri-food sectors. Sections highlight the green synthesis of copper nanoparticles, production mechanisms, eco-safety, and future perspectives, discuss the increasing importance of copper nanomaterials in plant protection applications, describe the use of copper nanostructures in plant science applications, cover antimicrobial applications, explore copper nanostructure applications, and summarize current applications in agroecosystems, such as copper nanoparticles as nanosensors, their negative ecological effects, estimation risks, and more. Assesses the impact of a large variety of copper-based nanostructures on the agri-food sector Discusses how the properties of a variety of copper-based nanomaterials make them effective for agricultural applications Explains the challenges surrounding the mass production of copper-based nanomaterials

Advances in Biomaterials for Biomedical Applications

Advances in Biomaterials for Biomedical Applications Book
Author : Anuj Tripathi,Jose Savio Melo
Publisher : Springer
Release : 2017-01-24
ISBN : 9811033285
Language : En, Es, Fr & De

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Book Description :

This book highlights recent advances in the field of biomaterials design and the state of the art in biomaterials applications for biomedicine. Addressing key aspects of biomaterials, the book explores technological advances at multi-scale levels (macro, micro, and nano), which are used in applications related to cell and tissue regeneration. The book also discusses the future scope of bio-integrated systems. The contents are supplemented by illustrated examples, and schematics of molecular and cellular interactions with biomaterials/scaffolds are included to promote a better understanding of the complex biological mechanisms involved in material-to-biomolecule interactions. The book also covers factors that govern cell growth, differentiation, and regeneration in connection with the treatment and recovery of native biological systems. Tissue engineering, drug screening and delivery, and electrolyte complexes for biomedical applications are also covered in detail. This book offers a comprehensive reference guide for multi-disciplinary communities working in the area of biomaterials, and will benefit researchers and graduate students alike.

Nanobiomaterials in Antimicrobial Therapy

Nanobiomaterials in Antimicrobial Therapy Book
Author : Alexandru Grumezescu
Publisher : William Andrew
Release : 2016-03-08
ISBN : 0323428878
Language : En, Es, Fr & De

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Book Description :

Nanobiomaterials in Antimicrobial Therapy presents novel antimicrobial approaches that enable nanotechnology to be used effectively in the treatment of infections. This field has gained a large amount of interest over the last decade, in response to the high resistance of pathogens to antibiotics. Leading researchers from around the world discuss the synthesis routes of nanobiomaterials, characterization, and their applications as antimicrobial agents. The books covers various aspects: mechanisms of toxicity for inorganic nanoparticles against bacteria; the development of excellent carriers for the transport of a high variety of antimicrobials; the use of nanomaterials to facilitate both diagnosis and therapeutic approaches against infectious agents; strategies to control biofilms based on enzymes, biosurfactants, or magnetotactic bacteria; bacterial adhesion onto polymeric surfaces and novel materials; and antimicrobial photodynamic inactivation. This book will be of interest to postdoctoral researchers, professors and students engaged in the fields of materials science, biotechnology and applied chemistry. It will also be highly valuable to those working in industry, including pharmaceutics and biotechnology companies, medical researchers, biomedical engineers and advanced clinicians. A methodical approach to this highly relevant subject for researchers, practitioners and students working in biomedical, biotechnological and engineering fields A valuable guide to recent scientific progress and the latest application methods Proposes novel opportunities and ideas for developing or improving technologies in nanomedicine and nanobiology

Emerging Nanomaterials and Nano based Drug Delivery Approaches to Combat Antimicrobial Resistance

Emerging Nanomaterials and Nano based Drug Delivery Approaches to Combat Antimicrobial Resistance Book
Author : Muthupandian Saravanan,Hamed Barabadi,Ebrahim Mostafavi,Thomas J. Webster
Publisher : Elsevier
Release : 2022-06-24
ISBN : 0323998100
Language : En, Es, Fr & De

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Book Description :

Emerging Nanomaterials and Nano-based Drug Delivery Approaches to Combat Antimicrobial Resistance focuses on recent and emerging trends surrounding nanomaterials and nano-drug delivery approaches to combat antimicrobial resistance. The relationship between nanomaterials and antimicrobial activity needs to be deeply explored to meet the challenges of combating antimicrobial resistance. The content of this book is divided into three main topic areas, including (i) how to overcome the existing traditional approaches to combat antimicrobial resistance, (ii) applying multiple drug delivery mechanisms to target multi-drug resistant microbes, and (iii) how nanomaterials can be used as drug carriers. This is an important reference source for those looking to understand how nanotechnology plays an important role in combatting disease and infection. As antimicrobial resistance threatens the effective prevention and treatment of an ever-increasing range of infections caused by bacteria, parasites, viruses, and fungi, this is a timely resource. Outlines how to overcome existing traditional approaches to combatting antimicrobial resistance Explains how to apply multiple drug delivery mechanisms (MDR) to the target area in order to better combat antimicrobial resistance Shows how nanomaterials are used as drug carriers in this context

Materials for Biomedical Engineering Bioactive Materials for Antimicrobial Anticancer and Gene Therapy

Materials for Biomedical Engineering  Bioactive Materials for Antimicrobial  Anticancer  and Gene Therapy Book
Author : Alexandru Grumezescu,Alina-Maria Holban
Publisher : Elsevier
Release : 2019-06-28
ISBN : 0128184361
Language : En, Es, Fr & De

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Book Description :

Materials for Biomedical Engineering: Bioactive Materials for Antimicrobial, Anticancer, and Gene Therapy offers an up-to-date perspective on recent research findings regarding the application and use of these materials for disease treatment and prevention. Various types of currently investigated bioactive materials, including therapeutic nanostructures and antimicrobial hydrogels are discussed, as are their properties, impact and future role in therapeutic applications. The book will be extremely useful for new researchers who want to explore more information on the use of bioactive materials or for more experienced researchers who are interested in new trends and specific applications. Provides knowledge on the range of bioactive materials available, enabling the reader to make optimal materials selection decisions Contains detailed information on current and proposed applications of the latest bioactive materials to empower readers to design innovative products and processes Presents a strong emphasis on chemistry and the physico-chemical characterization of these materials and their application in antimicrobial, anticancer and gene therapy

Nanoemulsions

Nanoemulsions Book
Author : Kai Seng Koh,Voon Loong Wong
Publisher : BoD – Books on Demand
Release : 2019-09-11
ISBN : 1789841755
Language : En, Es, Fr & De

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Book Description :

Fluidics, an increasingly examined topic in nanoscience and nanotechnology is often discussed with regard to the handling of fluid flow, material processing, and material synthesis in innovative devices ranging from the macroscale to the nanoscale. Nanoemulsions - Properties, Fabrications and Applications reviews key concepts in nanoscale fluid mechanics, its corresponding properties, as well as the latest trends in nanofluidics applications. With attention to the fundamentals as well as advanced applications of fluidics, this book imparts a solid knowledge base and develops skill for future problem-solving and system analysis. This is a vital resource for upper-level engineering students who want to expand their potential career opportunities and familiarize themselves with an increasingly important field.

Silver Micro Nanoparticles

Silver Micro Nanoparticles Book
Author : Samir Kumar,Prabhat Kumar,Chandra Shakher Pathak
Publisher : BoD – Books on Demand
Release : 2021-09-15
ISBN : 1839686596
Language : En, Es, Fr & De

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Book Description :

This book describes the different methodologies for producing and synthesizing silver nanoparticles (AgNPs) of various shapes and sizes. It also provides an in-depth understanding of the new methods for characterizing and modifying the properties of AgNPs as well as their properties and applications in various fields. This book is a useful resource for a wide range of readers, including scientists, engineers, doctoral and postdoctoral fellows, and scientific professionals working in specialized fields such as medicine, nanotechnology, spectroscopy, analytical chemistry diagnostics, and plasmonics.

Nano biomaterials in Antimicrobial Therapy

Nano biomaterials in Antimicrobial Therapy Book
Author : Pratima Parashar Pandey
Publisher : Unknown
Release : 2016
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Silver nanoparticles (AgNps) have attracted much interest in biomedical engineering, since they have excellent antimicrobial properties. Silver nanopolymer composites have applications in biochemical sensors, antimicrobial activity and drug delivery system. Silver nanoparticles are more effective than ionic homologues (Ag+) for their antimicrobial activity. Antimicrobial properties of silver nanoparticles are used by their incorporation into medical devices, tissues and other health-related products for skin pathologies to reduce the risk of contamination and to promote higher preventive infection control. Novel hybrid material thin films based on various polymeric systems with embedded silver nanoparticles were synthesized using various methods. The electrical, optical and plasmonic responses of AgNps onto thin layers of polymer composites show encapsulation of nanoparticles. The antibacterial activity of AgNps/polymer composites against various common bacteria is discussed in this chapter. The antibacterial activity of the synthesized hybrid materials was tested against various bacteria, commonly found in hospital environment. Silver nanostructures have especially been of interest because of contrast agents for biomedical image. Shunts used for hydrocephalous silicon elastomer grafted with hydrogel, polyvinylpyrrolidone (PVP) soaked in various antibiotics proved to be active for longer time.

Bioenergy and Biofuels

Bioenergy and Biofuels Book
Author : Ozcan Konur
Publisher : CRC Press
Release : 2018-01-02
ISBN : 1138032824
Language : En, Es, Fr & De

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Book Description :

This book aims to inform readers about the recent developments in bioenergy and biofuels covering current issues from an interdisciplinary approach. It will also feature coverage of anticipated future trends related to each particular biofuel. Chapters will consist of original research presented by world class experts in their respective fields. A number of interdisciplinary areas will be incorporated such as Energy & Fuels, Biotechology, Genomics, Economics, Optimization, Chemical Engineering, Mechanical Engineering and Algae Science. Examples will relate to a matrix of biofuel and energy types such as bioethanol, biobutanol, and biomethane.