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Nanoparticle Therapeutics

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Nanoparticle Therapeutics

Nanoparticle Therapeutics Book
Author : Prashant Kesharwani,Kamalinder K. Singh
Publisher : Academic Press
Release : 2021-11-06
ISBN : 0128209186
Language : En, Es, Fr & De

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Book Description :

Nanoparticle therapeutics: Production Technologies, Types of Nanoparticles, and Regulatory Aspects employs unique principles for applications in cell-based therapeutics, diagnostics and mechanistics for the study of organ physiology, disease etiology and drug screening of advanced nanoparticles and nanomaterials. The book focuses on the extrapolation of bioengineering tools in the domain of nanotechnology and nanoparticles therapeutics, fabrication, characterization and drug delivery aspects. It acquaints scientists and researchers on the experiential and experimental aspects of nanoparticles and nanotechnology to equip their rational application in various fields, especially in differential diagnoses and in the treatment of diverse diseased states. This complete resource provides a holistic understanding of the principle behind formation, characterization, applications, regulations and toxicity of nanoparticles employing myriad principles of nanotechnology. Investigators, pharmaceutical researchers, and advanced students working on technology advancement in the areas of designing targeted therapies, nanoscale imaging systems and diagnostic modalities in human diseases where nanoparticles can be used as a critical tool for technology advancement in drug delivery systems will find this book useful. Brings together the novel applications of nanotechnology in biological fields Explores perspectives on technologies through highly organized tables, illustrative figures and flow charts Addresses key multidisciplinary challenges faced by nanotechnologists to foster collaboration among biologists, chemists, physicists, engineers and clinicians

Polymeric Nanoparticles as a Promising Tool for Anti cancer Therapeutics

Polymeric Nanoparticles as a Promising Tool for Anti cancer Therapeutics Book
Author : Prashant Kesharwani,Kishore M. Paknikar,Virendra Gajbhiye
Publisher : Academic Press
Release : 2019-07-08
ISBN : 0128173319
Language : En, Es, Fr & De

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Book Description :

Polymeric Nanoparticles as Promising Tool for Anti-cancer Therapeutics provides an understanding of polymeric compounds and their use in cancer therapies. The book begins by giving an overview of the current status, future challenges and potential utilization of polymeric nanoparticles. It then covers specific polymeric nanoparticles through contributions from world-renowned experts and researchers. Chapters examine specific polymeric nanoparticles, their development as potential targeted delivery systems, and cancer characteristics that can be targeted for therapy development. The book synthesizes current research trends in the field, thus enhancing existing knowledge of nanomedicine, drug delivery and therapeutic intervention strategies in human cancers. Users will find this to be an ideal reference for research scientists and those in the pharmaceutical and medical fields who are working to develop novel cancer therapies using nanoparticle-based delivery systems. Explores the development of polymeric nanoparticle systems for the purpose of cancer therapy Presents thoroughly analyzed data and results regarding the usage of polymeric nanoparticles-based platforms for the diagnosis and treatment of cancer Highlights various cancer characteristics that can be targeted for therapeutic development using polymeric nanoparticles

RNA Nanotechnology and Therapeutics

RNA Nanotechnology and Therapeutics Book
Author : Peixuan Guo,Farzin Haque
Publisher : CRC Press
Release : 2013-07-09
ISBN : 1466505664
Language : En, Es, Fr & De

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Book Description :

Interest in RNA nanotechnology has increased in recent years as recognition of its potential for applications in nanomedicine has grown. Edited by the world's foremost experts in nanomedicine, this comprehensive, state-of-the-art reference details the latest research developments and challenges in the biophysical and single molecule approaches in RNA nanotechnology. In addition, the text also provides in-depth discussions of RNA structure for nanoparticle construction, RNA computation and modeling, single molecule imaging of RNA, RNA nanoparticle assembly, RNA nanoparticles in therapeutics, RNA chemistry for nanoparticle synthesis, and conjugation and labeling.

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids Book
Author : Surendra Nimesh,Ramesh Chandra,Nidhi Gupta
Publisher : Woodhead Publishing
Release : 2017-04-04
ISBN : 0081005636
Language : En, Es, Fr & De

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Book Description :

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles mediated NA would be discussed, with focus on their clinical relevance. The design and development of nucleic acid-based therapeutics for the treatment of diseases arising from genetic abnormalities has made significant progress over the past few years. NAs have been widely explored for the treatment of cancer and infectious diseases or to block cell proliferation and thereby caused diseases. Advances in synthetic oligonucleotide chemistry resulted in synthesis of NAs that are relatively stable in in vivo environments. However, cellular targeting and intracellular delivery of NAs still remains a challenge. Further development of NA-based therapeutics depends on the progress of safe and effective carriers for systemic administration. Nanomedicine has facilitated availability of vectors with diminished cytotoxicity and enhanced efficacy which are rapidly emerging as systems of choice. These vectors protect NAs from enzymatic degradation by forming condensed complexes along with targeted tissue and cellular delivery. During the past few years, a myriad reports have appeared reporting delivery of NAs mediated by nanoparticles. This book will provide an overview of nanoparticles being employed in the in vitro and in vivo delivery of therapeutically relevant NAs like DNA, siRNA, LNA, PNA, etc. Provides a complete overview of the applicatiosn of nanomedicine in the delivery of nucleic acids, from characterization of nanoparticles, to in vitro and in vivo studies Discusses delivery issues of less well explored nucleic acids, like PNAs, Ribozymes, DNAzymes, etc. Summarizes the current state of research in nucleic acid delivery and underscores the future of nanomedicine in this field

Nanobiotechnology in Diagnosis Drug Delivery and Treatment

Nanobiotechnology in Diagnosis  Drug Delivery and Treatment Book
Author : Mahendra Rai,Mehdi Razzaghi-Abyaneh,Avinash P. Ingle
Publisher : John Wiley & Sons
Release : 2020-12-02
ISBN : 1119671779
Language : En, Es, Fr & De

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Book Description :

Presents nanobiotechnology in drug delivery and disease management Featuring contributions from noted experts in the field, this book highlights recent advances in the nano-based drug delivery systems. It also covers the diagnosis and role of various nanomaterials in the management of infectious diseases and non-infectious disorders, such as cancers and other malignancies and their role in future medicine. Nanobiotechnology in Diagnosis, Drug Delivery and Treatment starts by introducing how nanotechnology has revolutionized drug delivery, diagnosis, and treatments of diseases. It then focuses on the role of various nanocomposites in diagnosis, drug delivery, and treatment of diseases like cancer, Alzheimer's disease, diabetes, and many others. Next, it discusses the application of a variety of nanomaterials in the diagnosis and management of gastrointestinal tract disorders. The book explains the concept of nanotheranostics in detail and its role in effective monitoring of drug response, targeted drug delivery, enhanced drug accumulation in the target tissues, sustained as well as triggered release of drugs, and reduction in adverse effects. Other chapters cover aptamer-incorporated nanoparticle systems; magnetic nanoparticles; theranostics and vaccines; toxicological concerns of nanomaterials used in nanomedicine; and more. Provides a concise overview of state-of-the-art nanomaterials and their application like drug delivery in infectious diseases and non-infectious disorders Highlights recent advances in the nano-based drug delivery systems and role of various nanomaterials Introduces nano-based sensors which detect various pathogens Covers the use of nanodevices in diagnostics and theranostics Nanobiotechnology in Diagnosis, Drug Delivery and Treatment is an ideal book for researchers and scientists working in various disciplines such as microbiology, biotechnology, nanotechnology, pharmaceutical biotechnology, pharmacology, pharmaceutics, and nanomedicine.

Nano Drug Delivery Strategies for the Treatment of Cancers

Nano Drug Delivery Strategies for the Treatment of Cancers Book
Author : Awesh K. Yadav,Umesh Gupta,Rajeev Sharma
Publisher : Academic Press
Release : 2020-09-03
ISBN : 0128197943
Language : En, Es, Fr & De

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Book Description :

Nano Drug Delivery Strategies for the Treatment of Cancers discusses several current and promising approaches for the diagnosis and treatment of cancer by using the most recent developments in nanomedical technologies. The book presents introductory information about the biology of different types of cancer in order to provide the reader with knowledge on their specificities. In addition, it discusses various novel drug delivery systems, detailing their functionalities, expected outcomes and future developments in the field, focusing on brain, mouth and throat, breast, lung, liver, pancreas, stomach, colon, bool, skin and prostate cancers. The book is a valuable source for cancer researchers, oncologists, pharmacologists and nanotechnologists who are interested in novel drug delivery systems and devices for treatment of various types of cancer that take advantage of recent advances in this exciting field. Discusses a wide range of promising approaches for the diagnosis and treatment of cancer using the latest advancement in cutting-edge nanomedical technologies Provides foundational information on different types of cancer and their biology to help the reader choose the best nano drug delivery system for patients Presents novel drug delivery systems based on nanoparticles, microparticles, liposomes, self-assembling Micelles and block copolymer micelles

Handbook on Nanobiomaterials for Therapeutics and Diagnostic Applications

Handbook on Nanobiomaterials for Therapeutics and Diagnostic Applications Book
Author : Krishnan Anand,Muthupandian Saravanan,Balakumar Chandrasekaran,Suvardhan Kanchi,Sarojini Jeeva Panchu,Quan-Sheng Chen
Publisher : Elsevier
Release : 2021-03-18
ISBN : 0128219149
Language : En, Es, Fr & De

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Book Description :

Handbook of Nano-biomaterials for Therapeutics and Diagnostic Applications covers in-depth topics on nano-biomaterials and nano drug delivery systems (biosensors and bioimaging) involving polymer nanocomposites, metal nanocomposites, and other carbon family fibers and proteins. The book covers the current application of tiny machines or nanodevices and their use as early detection systems for life threatening diseases, giving detailed literature on the development of nanodevices, their use as diagnostic tools, and their present trend in the industry and market. In addition, their synthesis, potential applications and future of smart nanodevices in diagnosis of diseases and their use as smart clinical devices is covered. Users will find sections on recent advances in interdisciplinary research on the processing, morphology, structure and properties of nanostructured materials and their applications in drug delivery for various diseases such as cancer, tuberculosis, Alzheimer disease, ophthalmic diseases, and more. Offers a comprehensive coverage of the therapeutics and smart nanodevices as diagnostic tools and their potential clinical applications in biosensing and bioimaging Includes a glimpse into the nano-biomaterials that are essential components in nanomedicines Describes nanodevices in the early diagnosis of the diseases Explains the nano-drug delivery system for the treatment of various diseases, including cancer, tuberculosis, Alzheimer disease, and ophthalmic diseases Encompasses all information, starting from the design of nano-biomaterials to their applications in theranostics

Nanomedicine for Drug Delivery and Therapeutics

Nanomedicine for Drug Delivery and Therapeutics Book
Author : Ajay Kumar Mishra
Publisher : John Wiley & Sons
Release : 2013-02-01
ISBN : 1118635841
Language : En, Es, Fr & De

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Book Description :

This book describes a broad area of nanomedicine which involves mainly applications, diseases, and diagnostics. The comprehensive coverage provides researchers, academics, and health specialists with a great tool, that includes techniques applicable to various uses.

Nanoscience and Technology

Nanoscience and Technology Book
Author : Anonim
Publisher : Unknown
Release : 2023-02-01
ISBN : 9814466867
Language : En, Es, Fr & De

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Book Description :

Download Nanoscience and Technology book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Nanoparticles in Medicine

Nanoparticles in Medicine Book
Author : Ashutosh Kumar Shukla
Publisher : Springer Nature
Release : 2019-08-31
ISBN : 9811389543
Language : En, Es, Fr & De

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Book Description :

This book describes the medical applications of inorganic nanoparticles. Nanomedicine is a relatively advanced field, which enhances the treatment of various diseases, offering new options for overcoming the problems associated with the use of conventional medicines. Discussing the toxicological and safety aspects associated with medical applications of nanoparticles, the book presents the latest research on topics such as emerging nanomaterials for cancer therapy, applications of nanoparticles in dentistry, and fluoride nanoparticles for biomedical applications, and also includes chapters on the use of nanoparticles such as silver and gold. /div

Nanoparticles in Pharmacotherapy

Nanoparticles in Pharmacotherapy Book
Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Release : 2019-04-24
ISBN : 0128165049
Language : En, Es, Fr & De

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Book Description :

Nanoparticles in Pharmacotherapy explores the most recent findings on how nanoparticles are used in pharmacotherapy, starting with their synthesis, characterization and current or potential uses. This book is a valuable resource of recent scientific progress that includes the most cutting-edge applications of nanoparticles in pharmacotherapy. It is ideal for researchers, medical doctors and those in academia.

DNA Engineered Noble Metal Nanoparticles

DNA Engineered Noble Metal Nanoparticles Book
Author : Ignác Capek
Publisher : John Wiley & Sons
Release : 2015-03-23
ISBN : 1119120934
Language : En, Es, Fr & De

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Book Description :

There is a growing interest in the use of nanoparticles modifiedwith DNAs, viruses, peptides and proteins for the rational designof nanostructured functional materials and their use in biosensorapplications. The challenge is to control the organization ofbiomolecules on nanoparticles while retaining their biologicalactivity as potential chemical and gene therapeutics. Thesenoble metal nanoparticles/biomolecules conjugates have specificproperties and therefore they are attractive materials fornanotechnology in biochemistry and medicine. In this book, the author review work performed dealing with theDNA structure and functionalities, interactions between DNA, noblemetal nanoparticles, surface active agents, solvents and otheradditives. Particular attention is given to how the DNA’schain length and the DNA conformation affect the interaction andstructure of the nanoconjugates and nanostructures that are formed.Also discussed are the recent advances in the preparation,characterization, and applications of noble metal nanoparticlesthat are conjugated with DNA aptamers and oligomers. The advantagesand disadvantages of functionalized nanoparticles through variousdetection modes are highlighted, including colorimetry,fluorescence, electrochemistry, SPR, and, mass spectrometry for thedetection of small molecules and biomolecules. The functionalizednoble metal nanoparticles are selective and sensitive for theanalytes, showing their great potential in biosensing. Furthermore,this book reviews recent progress in the area of DNA-noble metalnanoparticles based artificial nanostructures, that is, thepreparation, collective properties, and applications of variousDNA-based nanostructures are also described.

Multifunctional Nanoparticles for Drug Delivery Applications

Multifunctional Nanoparticles for Drug Delivery Applications Book
Author : Sonke Svenson,Robert K. Prud'homme
Publisher : Springer Science & Business Media
Release : 2012-02-22
ISBN : 146142304X
Language : En, Es, Fr & De

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Book Description :

This book presents the medical challenges that can be reduced or even overcome by recent advances in nanoscale drug delivery. Each chapter highlights recent progress in the design and engineering of select multifunctional nanoparticles.

Nanomaterials for Drug Delivery and Therapy

Nanomaterials for Drug Delivery and Therapy Book
Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Release : 2019-03-14
ISBN : 0128166290
Language : En, Es, Fr & De

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Book Description :

Nanomaterials for Drug Delivery and Therapy presents recent advances in the field of nanobiomaterials and their important applications in drug delivery, therapy and engineering. The book offers pharmaceutical perspectives, exploring the development of nanobiomaterials and their interaction with the human body. Chapters show how nanomaterials are used in treatments, including neurology, dentistry and cancer therapy. Authored by a range of contributors from global institutions, this book offers a broad, international perspective on how nanotechnology-based advances are leading to novel drug delivery and treatment solutions. It is a valuable research resource that will help both practicing medics and researchers in pharmaceutical science and nanomedicine learn more on how nanotechnology is improving treatments. Assesses the opportunities and challenges of nanotechnology-based drug delivery systems Explores how nanotechnology is being used to create more efficient drug delivery systems Discusses which nanomaterials make the best drug carriers

Design of Nanostructures for Theranostics Applications

Design of Nanostructures for Theranostics Applications Book
Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Release : 2018-01-15
ISBN : 0128136707
Language : En, Es, Fr & De

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Book Description :

Design of Nanostructures for Theranostics Applications focuses on the theranostics applications of nanostructures. In particular, multifunctional nanoparticles for diagnostics and treatment of different diseases, including those relating to the blood-brain barrier, are discussed in detail. Chapters explore different type of nanostructures, covering design, fabrication, functionalization and optimization, helping readers obtain the desired properties. Written by a diverse range of international academics, this book is a valuable reference resource for those working in both nanoscience and the pharmaceutical industry. Explores how the design of a range of nanomaterials make them effective theranostic agents, including multifunctional core-shell nanostructures, mesoporous silica nanoparticles, and quantum dots Shows how nanomaterials are used effectively for a range of diseases, including breast cancer, prostate cancer and neurological disorders Assesses the pros and cons of using different nanomaterials for different types of treatment

Alzheimer s Disease Theranostics

Alzheimer   s Disease Theranostics Book
Author : Magisetty Obulesu
Publisher : Academic Press
Release : 2019-01-20
ISBN : 0128167394
Language : En, Es, Fr & De

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Book Description :

Alzheimer’s Disease Theranostics discusses the latest information on recent theranostic avenues for both the diagnosis and treatment of Alzheimer’s patients. It presents the pros and cons of the probable mechanistic role of nanoparticles in crossing the blood-brain barrier and improving disease symptoms. Finally, it highlights the merits of existing maneuvers and suggests perspectives to aid in future developments. Despite the difficulty of drug delivery to the brain, there are some nanoparticulate platforms demonstrating promise in treating neurodegenerative disorders such as Alzheimer’s disease. Manifold theranostic maneuvers include antioxidants, natural bioactive compounds, gene therapy, and nanotechnological approaches, all of which are discussed in this important work. Examines various theranostic applications for the diagnosis and treatment of Alzheimer’s disease Features a comprehensive overview of nanoparticle therapeutics in the area and use of antioxidants Assesses the common challenges and lessons learned from blood-brain barrier challenges, viral vector approaches and mitochondria-targeted therapeutics

Nanoparticles Induce Oxidative and Endoplasmic Reticulum Stresses

Nanoparticles Induce Oxidative and Endoplasmic Reticulum Stresses Book
Author : Loutfy H. Madkour
Publisher : Springer
Release : 2020-03-14
ISBN : 9783030372965
Language : En, Es, Fr & De

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Book Description :

This book provides insights and tools for better understanding redox biology and medicine and, in the long run, to finding new therapeutic strategies to target dysregulated redox processes in various diseases. It presents the recent advances in new nanomedication technologies of the effects of nanoparticles NPs on oxidative stress, RONS and ER stress. The book comprises 13 chapters covering ecotoxicology, cytotoxicity, nanotoxicity and genotoxicity mechanisms causing by the role and interactions of nanoparticles and free radicals with (RONS) and (ER) stress. Endoplasmic Reticulum (ER) Stress as a mechanism for NPs induced toxicity has been discussed. The advances of nanotechnology and the effects of nanoparticles on oxidative stress, ROS and ER stress parameters are discussed. Antioxidants, therapeutic options and regulation of the immune responses are explained throughout the book.

Biological Synthesis of Nanoparticles and Their Applications

Biological Synthesis of Nanoparticles and Their Applications Book
Author : L Karthik,A. Vishnu Kirthi,Shivendu Ranjan,V. Mohana Srinivasan
Publisher : CRC Press
Release : 2019-12-06
ISBN : 0429560257
Language : En, Es, Fr & De

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Book Description :

Biological Synthesis of Nanoparticles and Their Applications gives insight into the synthesis of nanoparticles utilizing the natural routes. It demonstrates various strategies for the synthesis of nanoparticles utilizing plants, microscopic organisms like bacteria, fungi, algae and so forth. It orchestrates interdisciplinary hypothesis, ideas, definitions, models and discoveries associated with complex cell of the prokaryotes and eukaryotes. Highlights: Discusses biological approach towards the nanoparticle synthesis Describes the role of nanotechnology in the field of medicine and its medical devices Covers application and usage of the chemicals at the molecular level to act as catalysts and binding products for both organic and inorganic Chemical Reactions Reviews application in physics such as solar cells, photovoltaics and other usage Microorganisms can aggregate and detoxify substantial metals because of different reductase enzymes, which can diminish metal salts to metal nanoparticles. The readers after going through this book will have detailed account of mechanism of bio-synthesis of nanoparticles.

Nanotechnology Based Targeted Drug Delivery Systems for Lung Cancer

Nanotechnology Based Targeted Drug Delivery Systems for Lung Cancer Book
Author : Prashant Kesharwani
Publisher : Academic Press
Release : 2019-01-26
ISBN : 0128163674
Language : En, Es, Fr & De

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Book Description :

Nanotechnology-based Targeted Drug Delivery Systems for Lung Cancer is an indispensable resource that will help pharmaceutical scientists and clinical researchers design and develop novel drug delivery systems and devices for the treatment of lung cancer. As recent breakthroughs in nanomedicine are now making it possible to deliver drugs, genes and therapeutic agents to localized areas of disease to maximize clinical benefit, while also limiting unwanted side effects, this book explores promising approaches for the diagnosis and treatment of lung cancer using cutting-edge nanomedical technologies. Topics discussed include polymeric nanoparticles, solid lipid nanoparticles, liposomes, dendrimers, micelles and nanoemulsions. Provides an overview of an array of nanotechnology-based drug delivery systems Examines the design, synthesis and application of different nanocarriers in drug and gene delivery Provides an in-depth understanding of the design of targeted nanotherapeutics and technologies and its implication in various site-specific cancers