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Multiple Sclerosis 3

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Multiple Sclerosis 3 Volume 34 E Book

Multiple Sclerosis 3  Volume 34 E Book Book
Author : Claudia Lucchinetti,Reinhard Hohlfeld
Publisher : Elsevier Health Sciences
Release : 2009-10-29
ISBN : 1437711294
Language : En, Es, Fr & De

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Book Description :

Multiple Sclerosis 3 emphasizes the latest in the pharmacologic treatment of this incurable inflammatory demyelinating disorder. Primary editors Claudia Lucchinetti, MD, and Reinhard Hohlfeld, MD, with the aid of all new contributors, present a complete and current reference on multiple sclerosis that includes discussions of such hot topics as Biomarkers, Genomics, and Surrogate Outcomes in MS; Pediatric MS; Transverse Myelitis; Attack Therapies in MS; Current Disease-Modifying Therapeutic Strategies in MS; Management of Aggressive MS; Symptomatic Therapies in MS; Complementary and Alternative Medical Therapies; and Strategies to Promote Neuroprotection and Repair. Distinguish between MS and other similar demyelinating disorders and know the best and most aggressive methods of treatment. This title in the Blue Books of Neurology series is exactly what you need to treat the disease and its relapses. Covers the latest clinical advances and relevant discussions—Biomarkers, Genomics, and Surrogate Outcomes in MS; Pediatric MS; Transverse Myelitis; Attack Therapies in MS; Current Disease-Modifying Therapeutic Strategies in MS; Management of Aggressive MS; Symptomatic Therapies in MS; Complementary and Alternative Medical Therapies; and Strategies to Promote Neuroprotection and Repair—to bring you up to date and keep your practice state-of-the-art. Features a greater emphasis on practical management to help you determine the type of multiple sclerosis and the best course of therapy. Focuses on pharmaceutical therapies so you know the best and most aggressive methods and which drugs to use for treatment. Includes extensive information on differential diagnosis so that you can clearly distinguish between multiple sclerosis and other similar demyelinating disorders. Presents expert new editors and experienced contributing authors for the most current and relevant practice information. Emphasizes the pharmacologic management of patients with multiple sclerosis to address treating the actual disease and its relapses as well as treating the symptoms.

Multiple Sclerosis 3

Multiple Sclerosis 3 Book
Author : Anonim
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Multiple Sclerosis

Multiple Sclerosis Book
Author : Neil Scolding,Alastair Wilkins
Publisher : Oxford University Press, USA
Release : 2012-07-05
ISBN : 0199603251
Language : En, Es, Fr & De

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Book Description :

Part of the Oxford Neurology Library series, this practical pocketbook will summarise the latest understanding of what might cause the disease, the methods of diagnosis and assessment, and current management techniques.

A History of Multiple Sclerosis and Medicine in the United States 1870 1960

A History of Multiple Sclerosis and Medicine in the United States  1870 1960 Book
Author : Colin Lee Talley
Publisher : Unknown
Release : 1998
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download A History of Multiple Sclerosis and Medicine in the United States 1870 1960 book written by Colin Lee Talley, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Handbook of Multiple Sclerosis

Handbook of Multiple Sclerosis Book
Author : Stuart D. Cook
Publisher : CRC Press
Release : 2001-03-30
ISBN : 9780824741846
Language : En, Es, Fr & De

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Book Description :

Reporting on the latest advances made in treating multiple sclerosis (MS) and continuing the high standards set by earlier editions, the Handbook of Multiple Sclerosis, Third Edition examines a wide range of topics from etiology to treatment options. Analyzes recent developments in the natural history, immunopathology, lesion evolution, and

Multiple sclerosis 3 treatment and prognosis

Multiple sclerosis   3 treatment and prognosis Book
Author : Simon Hammond
Publisher : Unknown
Release : 1988
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Multiple sclerosis 3 treatment and prognosis book written by Simon Hammond, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

McAlpine s Multiple Sclerosis

McAlpine s Multiple Sclerosis Book
Author : Alastair Compston,Douglas McAlpine,George Ebers,Hans Lassmann,Bryan Matthews,Hartmut Wekerle
Publisher : Elsevier Science Health Science Division
Release : 1998
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This is the latest edition of the classic book on the subject of multiple sclerosis. An international group of authors has been involved in updating this edition which features more information on imaging and investigations, and a new chapter on neurobiology and glial development. new edition of the classic book on the subject four new authors, all internationally known authorities from UK, Canada, Germany & Austria much more on imaging and investigations than 2E new chapter on neurobiology and glial development much better illustrated than 2E very well referenced totally rewritten, except for chapters 2 & 3 on symptoms and diagnosis, which have been revised

Living with Multiple Sclerosis

Living with Multiple Sclerosis Book
Author : Mark Greener
Publisher : Hachette UK
Release : 2017-02-16
ISBN : 1847094147
Language : En, Es, Fr & De

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Book Description :

The last few years have witnessed a revolution in our understanding of multiple sclerosis (MS). New treatments have transformed the prospects for many who have this chronic disease and MS is increasingly a manageable disease. This book explains the latest medical thinking on MS. It explores how to ease symptoms such as balance and mobility problems, and how to get the best from medical treatments. The book also suggests self-help techniques and lifestyle changes that may help. Topics include: types of MS diagnosis drug treatment managing side effects treating pain and fatigue bladder, bowel, swallowing and other problems coping with the mental and emotional burden diet and MS complementary and alternative remedies

Multiple Sclerosis

Multiple Sclerosis Book
Author : J. F. Hallpike,Colin Wallace Maitland Adams,Wallace W. Tourtellotte
Publisher : Unknown
Release : 1983
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Multiple Sclerosis book written by J. F. Hallpike,Colin Wallace Maitland Adams,Wallace W. Tourtellotte, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Biomarkers and Disease Activity in Multiple Sclerosis

Biomarkers and Disease Activity in Multiple Sclerosis Book
Author : Irene Håkansson
Publisher : Linköping University Electronic Press
Release : 2019-10-07
ISBN : 9176850129
Language : En, Es, Fr & De

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Book Description :

This thesis focuses on disease activity in clinically isolated syndrome (CIS) and newly diagnosed relapsing remitting multiple sclerosis (RRMS). The papers are based on data from 41 patients in a prospective longitudinal cohort study. All patients were untreated at baseline. Age- and sex-matched healthy controls (n=22) for blood and cerebrospinal fluid (CSF) samples were recruited from blood donors. Paper I evaluated the prognostic value of baseline levels of CXCL1, CXCL8, CXCL10, CXCL13, CCL22, neurofilament light chain (NFL), neurofilament heavy chain, glial fibrillary acidic protein, chitinase-3-like-1 (CHI3L1), matrix metalloproteinase-9 (MMP-9) and osteopontin in CSF in relation to disease activity during the first two years of follow-up. Disease activity was defined as clinical relapses, new T2 lesions in brain magnetic resonance imaging (MRI) and/or sustained Expanded Disability Status Scale (EDSS) progression. Absence of these three signs of disease activity was called no evidence of disease activity (NEDA-3). Logistic regression analysis showed that NFL in CSF was the best predictive marker of disease activity and correctly classified 93% of the patients with evidence of disease activity during two years of follow-up and 67% of those without. Paper II presented four year follow-up data from the cohort and also included brain volume data as well as serum levels of NFL. The correlation between NFL in CSF and serum was fairly strong (r=0.74, p<0.001). NFL in CSF was associated with new T2 lesions as well as with brain volume loss, whereas CHI3L1 in CSF was associated mainly with brain volume loss and CXCL1, CXCL10, CXCL13, CCL22 and MMP-9 in CSF were mainly associated with new T2 lesions. Taken together, paper I and II confirm and extend the knowledge of NFL as a useful biomarker in CIS and RRMS and suggests that NFL, rather than total brain volume loss, could be included in an expanded NEDA concept and used in clinical monitoring of disease activity/treatment effect. Although serum levels of NFL were correlated with the corresponding CSF levels, CSF-NFL showed a stronger association to subsequent disease activity (NEDA-3). Paper III addressed the patients´ self-reported Modified Fatigue Impact Scale (MFIS) scores in relation to other cohort study data. MFIS scores correlated with other self-assessment questionnaire data (Hospital Anxiety and Depression scale (HAD), Multiple Sclerosis Impact Scale 29 (MSIS-29) and Short Form 36 (SF-36) scores (Spearman´s rho 0.45-0.78, all p?0.01)) but not with EDSS ratings, number of T2 lesions, total brain volume or NFL levels, indicating that subjective fatigue scores are not well reflected by some commonly used and objectively measurable disease parameters. Paper IV focused on the complement factors C1q, C3, C3a and sC5b-9 in CSF and plasma. CSFC1q was significantly higher in patients than in controls at baseline. The subgroup of patients with ongoing relapse at baseline also had higher levels of CSF-C3a than controls. Baseline levels of CSF-C1q and CSF-C3a correlated significantly with several pro-inflammatory chemokines as well as with MMP-9, CHI3L1 and NFL in CSF. Baseline CSF-C3a also correlated significantly with the number of T2 lesions and Gadolinium enhancing lesions in brain MRI at baseline, as well as with the number of new T2 lesions during follow-up. This study indicates that the complement system is involved already at early stages of MS. It also suggests that especially CSF-C1q and CSF-C3a levels are associated with other neuroinflammatory and neurodegenerative markers and that CSF-C3a levels may carry some prognostic information.

Multiple Sclerosis and Related Disorders

Multiple Sclerosis and Related Disorders Book
Author : Douglas S. Goodin
Publisher : Elsevier Science Limited
Release : 2014
ISBN : 9780444520012
Language : En, Es, Fr & De

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Book Description :

Multiple Sclerosis (MS) is generally understood to be an inflammatory autoimmune disease of the central nervous system. While we still are not certain of the root cause of MS, research results suggest that unknown environmental factors and the presence of specific genes seem the most probable targets. MS causes an inflammatory response in the central nervous system leading to neurodegeneration, oligodendrocyte death, axonal damage, and gliosis. Over the past five years ongoing research has greatly expanded our understanding of the pathogenesis of MS, detailed insight into the epidemiology and genetic factors related to MS, the introduction of new technologies and tests to better diagnose and predict the future course of the disease and the introduction of new treatments targeting MS. This collection of review chapters provides a comprehensive reference into the science and clinical applications of the latest Multiple Sclerosis research and will be a valuable resource for the neuroscience research community and the clinical neurology community of researchers and practitioners. *A comprehensive tutorial reference detailing our current foundational understanding of Multiple Sclerosis *Includes chapters on key topics including the genetics of MS, MRI imaging and MS, and the latest treatment options *Each chapter is translational and focuses on current research and impact on diagnosis and treatment options.

Multiple Sclerosis

Multiple Sclerosis Book
Author : Sigrid Poser
Publisher : Springer
Release : 1978-05-01
ISBN : 9783540086444
Language : En, Es, Fr & De

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Book Description :

The value of prospective long-term studies on the features and course of multiple sclerosis is determined by the reliability with which relevant infor mation is documented. This involves two basic problems: I) The docu mentation system used must be detailed enough to provide adequate data on the essential features and course of the disease in a given case; on the other hand, it must not be so complicated and cumbersome as to preclude its use in the routine care of MS patients. 2) Since no system can fully anticipate new problems and scientific approaches that may become impor tant at some future time, the system must be open to provide the possi bility of adding and correlating the data of special research studies with the . basic data. These considerations led to the development of the basic documentation system described here and employed for the analysis of clinical data in this monograph. The work was carried out with the help of the Deutsche Forschungsgemeinscha/t as a part of its research program on multiple sclerosis and related demyelinating disease. A basic documentation pool including the data of more than 2 000 patients has been accumulated in the last six years. The system has been put to practical use in a number of epidemiologic surveys completed or under way, in following up the cases in an epidemiologic observation area in South Lower Saxony, and in studies on spasticity, cerebrospinal fluid findings, clinical forms and neuro physiological aspects of MS.

Epidemiological Study of Multiple Sclerosis in Israel

Epidemiological Study of Multiple Sclerosis in Israel Book
Author : Anonim
Publisher : Unknown
Release : 1967
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Epidemiological Study of Multiple Sclerosis in Israel book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Epidemiology of Multiple Sclerosis

The Epidemiology of Multiple Sclerosis Book
Author : Milton Alter,John F. Kurtzke
Publisher : Unknown
Release : 1968
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Epidemiology of Multiple Sclerosis book written by Milton Alter,John F. Kurtzke, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Multiple Sclerosis Research

Multiple Sclerosis Research Book
Author : Alan Nelson Davison,Medical Research Council (Great Britain),Multiple Sclerosis Society of Great Britain and Northern Ireland
Publisher : Elsevier
Release : 1975
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Multiple Sclerosis Research book written by Alan Nelson Davison,Medical Research Council (Great Britain),Multiple Sclerosis Society of Great Britain and Northern Ireland, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Living at Your Best with Multiple Sclerosis

Living at Your Best with Multiple Sclerosis Book
Author : George Harry Hess
Publisher : Unknown
Release : 1962
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Living at Your Best with Multiple Sclerosis book written by George Harry Hess, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Multiple Sclerosis Fact Book

Multiple Sclerosis Fact Book Book
Author : Richard Lechtenberg
Publisher : F. A. Davis Company
Release : 1988
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

In terms understandable to the lay person, a doctor explains new developments in MS: the advantages and limitations of Betaseron (interferon beta-1b), the first drug recognized by the FDA for the treatment of some patients with MS; the use of Prozac and other antidepressants to combat psychological effects; experimental therapies, both conventional and unconventional; more effective drugs to treat impotence; new laws against discrimination in employment. The concise text and illustrations will help both the person with newly diagnosed MS and the individual who has been living with MS for years to understand the disease better and to continue to live successfully and fully.

Neurological Rehabilitation

Neurological Rehabilitation Book
Author : Darcy Ann Umphred
Publisher : Mosby
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Includes everything from basic theories to the breakthroughs in screening, treatments, diagnosis, and interventions, this edition is the neurology book for therapy students and clinicians. It takes a problem-solving approach to the therapeutic management of movement limitations, quality of life, and more.