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Multifunctional Theranostic Nanomedicines In Cancer

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Multifunctional Theranostic Nanomedicines in Cancer

Multifunctional Theranostic Nanomedicines in Cancer Book
Author : Malay K. Das
Publisher : Academic Press
Release : 2021-03-26
ISBN : 0128217006
Language : En, Es, Fr & De

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Book Description :

Multifunctional Theranostic Nanomedicines in Cancer focuses on new trends, applications, and the significance of novel multifunctional nanotheranostics in cancer imaging for diagnosis and treatment. Cancer nanotechnology offers new opportunities for cancer diagnosis and treatment. Multifunctional nanoparticles harboring various functions—including targeting, imaging, and therapy—have been intensively studied with the goal of overcoming the limitations of conventional cancer diagnosis and therapy. Thus theranostic nanomedicines have emerged in recent years to provide an efficient and safer alternative in cancer management. This book covers polymer-based therapies, lipid-based therapies, inorganic particle-based therapies, photo-related therapies, radiotherapies, chemotherapies, and surgeries. Multifunctional Theranostic Nanomedicines in Cancer offers an indispensable guide for researchers in academia, industry, and clinical settings; it is also ideal for postgraduate students; and formulation scientists working on cancer. Provides a comprehensive resource of recent scientific progress and novel applications of theranostic nanomedicines Discusses treatment options from a pharmaceutical sciences perspective Includes translational science and targeted CNS cancer treatment

Handbook of Nanomaterials for Cancer Theranostics

Handbook of Nanomaterials for Cancer Theranostics Book
Author : Joao Conde
Publisher : Elsevier
Release : 2018-06-27
ISBN : 0128133406
Language : En, Es, Fr & De

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Book Description :

Handbook of Nanomaterials for Cancer Theranostics focuses on recent developments in advanced theranostic nanomedicines from a chemical and biological perspective where the advantages of theranostics are achieved by combining multiple components. The authors explore the pros and cons of theranostic nanomaterials developed in cancer research in the last 15 years, with the different strategies compared and scrutinized. In addition, the book explores how nanomaterials may overcome the regulatory hurdles facing theranostic nanomedicines. This is an important research reference for postgraduates and researchers in nanomedicine and cancer research who want to learn more on how nanomaterials can help create more effective cancer treatments. Highlights the development of smart theranostic nanomaterials to tackle biomedical problems in cancer therapy and diagnostics Explores the regulatory hurdles facing theranostic nanomedicine Discusses how the use of nanomaterials can help create more effective cancer treatments

Advances in Nanotheranostics II

Advances in Nanotheranostics II Book
Author : Zhifei Dai
Publisher : Springer
Release : 2016-01-11
ISBN : 9811000638
Language : En, Es, Fr & De

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Book Description :

This book surveys recent advances in theranostics based on magnetic nanoparticles, ultrasound contrast agents, silica nanoparticles and polymeric micelles. It presents magnetic nanoparticles, which offer a robust tool for contrast enhanced MRI imaging, magnetic targeting, controlled drug delivery, molecular imaging guided gene therapy, magnetic hyperthermia, and controlling cell fate. Multifunctional ultrasound contrast agents have great potential in ultrasound molecular imaging, multimodal imaging, drug/gene delivery, and integrated diagnostics and therapeutics. Due to their diversity and multifunctionality, polymeric micelles and silica-based nanocomposites are highly capable of enhancing the efficacy of multimodal imaging and synergistic cancer therapy. This comprehensive book summarizes the main advances in multifunctional nanoprobes for targeted imaging and therapy of gastric cancer, and explores the clinical translational prospects and challenges. Although more research is needed to overcome the substantial obstacles that impede the development and availability of nanotheranostic products, such nontrivial nanoagents are expected to revolutionize medical treatments and help to realize the potential of personalized medicine to diagnose, treat, and follow-up patients with cancer. Zhifei Dai is a Professor at the Department of Biomedical Engineering, College of Engineering, Peking University, China.

Advances in Nanotheranostics I

Advances in Nanotheranostics I Book
Author : Zhifei Dai
Publisher : Springer
Release : 2015-12-15
ISBN : 3662485443
Language : En, Es, Fr & De

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Book Description :

This book highlights the recent advances in nanotheranostics from basic research to potential applications, and discusses the modular design and engineering of multiplex nanoparticles including gold nanostructures, luminescent nanoparticles, dendrimers and liposomes. Each chapter demonstrates multifunctional nanoparticles with topics covering targeting, imaging, delivery, diagnostics, and therapy as new modalities for cancer theranostics. This comprehensive book presents expert views on the latest developments in theranostic nanomedicine. It focuses on potential theranostic applications of multifunctional nanoparticles ranging from identifying noninvasively cancer cells by molecular detection, and visualizing in vivo drug delivery by means of contrast enhanced imaging, to destroying cancer cell s with minimal side effects via selective accumulation at tumor sites, and real-time monitoring therapeutic effectiveness. It also presents an interdisciplinary survey of nanotheranostics and as such is a valuable resource for researchers and students in related fields. Zhifei Dai is a Professor at the Department of Biomedical Engineering, College of Engineering, Peking University, China.

Advanced Theranostic Nanomedicine in Oncology

Advanced Theranostic Nanomedicine in Oncology Book
Author : Gianni Ciofani,Attilio Marino,Christos Tapeinos
Publisher : Frontiers Media SA
Release : 2020-03-18
ISBN : 2889636216
Language : En, Es, Fr & De

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Book Description :

Download Advanced Theranostic Nanomedicine in Oncology book written by Gianni Ciofani,Attilio Marino,Christos Tapeinos, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Bio Nanomedicine for Cancer Therapy

Bio Nanomedicine for Cancer Therapy Book
Author : Flavia Fontana,Hélder A. Santos
Publisher : Springer Nature
Release : 2021-02-04
ISBN : 3030581748
Language : En, Es, Fr & De

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Book Description :

The book covers the latest developments in biologically-inspired and derived nanomedicine for cancer therapy. The purpose of the book is to illustrate the significance of naturally-mimicking systems for enhancing the dose delivered to the tumor, to improve stability, and prolong the circulation time. Moreover, readers are presented with advanced materials such as adjuvants for immunostimulation in cancer vaccines. The book also provides a comprehensive overview of the current status of academic research. This is an ideal book for students, researchers, and professors working in nanotechnology, cancer, targeted drug delivery, controlled drug release, materials science, and biomaterials as well as companies developing cancer immunotherapy.

Engineering of Multifunctional Nanomaterials for Cancer Theranostics

Engineering of Multifunctional Nanomaterials for Cancer Theranostics Book
Author : Shreya Goel
Publisher : Unknown
Release : 2017
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Development of novel imaging probes for cancer diagnosis is critical for early disease detection and management. The past two decades have witnessed a surge in the development and evolution of radiolabeled nanoparticles as a new frontier in personalized cancer nanomedicine. The dynamic synergism of positron emission tomography (PET) and nanotechnology combines the sensitivity and quantitative nature of PET with the multifunctionality and tunability of nanomaterials, which can help overcome certain key challenges in the field. Silica, "generally recognized as safe" (GRAS) by the Food and Drug Administration (FDA) of the United States, has emerged as one of the leading nanomaterials employed for molecular imaging and therapy of a wide variety of diseases, including cancer. However in vivo biodistribution and active targeting of silica-based nanomaterials has remained a relatively under explored area, based mainly on semi-quantitative techniques such as fluorescence imaging. In this dissertation, I explore the concept of radiolabeled silica nanoparticles for vasculature-targeted imaging of different tumor types. Both chelator-based and chelator-free radiolabeling techniques were employed for accurate and quantitative analysis of the in vivo pharmacokinetics of radiolabeled silica nanomaterials. (Chapters 2 and 3) The large surface area, ease of tunability and facile silica chemistry were employed to create multifunctional silica-based materials to simultaneously seek-and-treat cancers, by incorporating multiple components into a single nanoplatform. Photodynamic agent, porphyrin was loaded into the central cavity of hollow mesoporous silica nanoparticles, and the shell was decorated with photothermal nanoparticles, CuS, yielding a multimodal theranostic nanoplatform which could synergistically annihilate the tumor without relapse. (Chapter 4) A major hurdle in the successful clinical translation of nanomaterials is their rapid sequestration by the organs of the reticuloendothelial system (RES), mainly liver and spleen, and prolonged retention in the body, raising long-term toxicity concerns. To combat this issue, two approaches were employed; (i) Synthesis of biodegradable mesoporous silica nanoparticles (Chapter 5), and (ii) development of ultrasmall nanoparticles including renal clearable Au nanoparticles and hepatically cleared ultrasmall mesoporous silica nanoparticles (Chapter 6); for prolonged blood circulation, enhanced tumor uptake and rapid clearance from the body, enabling unprecedented tumor-to-normal tissue contrast. Overall, the reported studies explore the synergism of molecular imaging and therapy, and nanotechnology. While the application of nanomaterials in the former imparts multifunctionality to the molecular agent, allowing multimodal imaging and synergistic therapeutic regimes to be carried out simultaneously; molecular imaging techniques such as PET, allow accurate measurement of the in vivo pharmacokinetics of the nanomaterials, playing a major role towards their successful clinical translation. Further work will be required to better understand the in vivo biodistribution of both biodegradable and ultrasmall nanomaterials, and further employ them for early and specific detection of cancer, effective treatment and monitoring.

Frontiers in Anti Cancer Drug Discovery Volume 11

Frontiers in Anti Cancer Drug Discovery  Volume 11 Book
Author : Atta-ur-Rahman ,Muhammad Iqbal Choudhary
Publisher : Bentham Science Publishers
Release : 2020-09-01
ISBN : 9811422125
Language : En, Es, Fr & De

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Book Description :

Frontiers in Anti-Cancer Drug Discovery is a book series devoted to publishing the latest advances in anti-cancer drug design and discovery. In each volume, eminent scientists contribute reviews relevant to all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The book series should prove to be of interest to all pharmaceutical scientists involved in research in anti-cancer drug design and discovery. The book series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field. The eleventh volume of the series focuses on reviews on targeted therapies and drug delivery systems. This volume covers the following topics: - PI3K/Akt/mTOR Pathway in Acute Lymphoblastic Leukemia Targeted Therapies - Polymeric Nanomedicines in Treatment of Breast Cancer: Review of Contemporary Research - Treatment of Lung Cancer in the New Era - Oral Administration of Cancer Chemotherapeutics Exploiting Self-Nanoemulsifying Drug Delivery System: Recent Progress and Application - Targeting Approaches for the Diagnosis and Treatment of Cancer.

Multifunctional Nanoparticles for Drug Delivery Applications

Multifunctional Nanoparticles for Drug Delivery Applications Book
Author : Sonke Svenson,Robert K. Prud'homme
Publisher : Springer Science & Business Media
Release : 2012-02-22
ISBN : 146142304X
Language : En, Es, Fr & De

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Book Description :

This book presents the medical challenges that can be reduced or even overcome by recent advances in nanoscale drug delivery. Each chapter highlights recent progress in the design and engineering of select multifunctional nanoparticles.

Nanotheranostics for Cancer Applications

Nanotheranostics for Cancer Applications Book
Author : Prakash Rai,Stephanie A. Morris
Publisher : Springer
Release : 2018-11-12
ISBN : 3030017753
Language : En, Es, Fr & De

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Book Description :

This book is the first to focus specifically on cancer nanotheranostics. Each of the chapters that make up this comprehensive volume is authored by a researcher, clinician, or regulatory agency member known for their expertise in this field. Theranostics, the technology to simultaneously diagnose and treat a disease, is a nascent field that is growing rapidly in this era of personalized medicine. As the need for cost-effective disease diagnosis grows, drug delivery systems that can act as multifunctional carriers for imaging contrast and therapy agents could provide unique breakthroughs in oncology. Nanotechnology has enabled the development of smart theranostic platforms that can concurrently diagnose disease, start primary treatment, monitor response and initiate secondary treatments if required. In oncology, chemotherapeutics have been routinely used. Some drugs have proven effective but all carry risks of adverse side effects. There is growing interest in using remotely triggered drug delivery systems to limit cytotoxicity in the diseased area. This book reviews the use of theranostic nanoparticles for cancer applications over the past decade. First, it briefly discusses the challenges and limitations of conventional cancer treatments, and presents an overview of the use of nanotechnology in treating cancer. These introductory chapters are followed by those exploring cancer diagnosis and a myriad of delivery methods for nanotherapeutics. The book also addresses multifunctional platforms, treatment monitoring, and regulatory considerations. As a whole, the book aims to briefly summarize the development and clinical potential of various nanotheranostics for cancer applications, and to delineate the challenges that must be overcome for successful clinical development and implementation of such cancer theranostics.

Lignin based Materials for Biomedical Applications

Lignin based Materials for Biomedical Applications Book
Author : Patrícia Figueiredo,Hélder A. Santos
Publisher : Elsevier
Release : 2021-07-30
ISBN : 0128203048
Language : En, Es, Fr & De

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Book Description :

Lignin-based Materials for Biomedical Applications: Preparation, Characterization, and Implementation explores the emerging area of lignin-based materials as a platform for advanced biomedical applications, guiding the reader from source through to implementation. The first part of the book introduces the basics of lignin, including extraction methods, chemical modifications, structure and composition, and properties that make lignin suitable for biomedical applications. In addition, structural characterization techniques are described in detail. The next chapters focus on the preparation of lignin-based materials for biomedical applications, presenting methodologies for lignin-based nanoparticles, hydrogels, aerogels, and nanofibers, and providing in-depth coverage of lignin-based materials with specific properties—including antioxidant properties, UV absorbing capability, antimicrobial properties, and colloidal particles with tailored properties—and applications, such as drug and gene delivery, and tissue engineering. Finally, future perspectives and possible new applications are considered. This is an essential reference for all those with an interest in lignin-based materials and their biomedical applications, including researchers and advanced students across bio-based polymers, polymer science, polymer chemistry, biomaterials, nanotechnology, materials science and engineering, drug delivery, and biomedical engineering, as well as industrial R&D and scientists involved with bio-based polymers, specifically for biomedical applications. Unlocks the potential of lignin-based materials with advanced properties for cutting-edge applications in areas such as drug delivery, gene delivery and tissue engineering Presents state-of-the-art methodologies used in the development of lignin-based nanoparticles, hydrogels, aerogels and nanofibers Explains the fundamentals of lignin, including structure and composition, extraction and isolation methods, types and properties, chemical modifications, and characterization techniques

Cancer Theranostics

Cancer Theranostics Book
Author : Xiaoyuan Chen,Stephen Wong
Publisher : Academic Press
Release : 2014-03-20
ISBN : 0124078842
Language : En, Es, Fr & De

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Book Description :

Aiding researchers seeking to eliminate multi-step procedures, reduce delays in treatment and ease patient care, Cancer Theranostics reviews, assesses, and makes pertinent clinical recommendations on the integration of comprehensive in vitro diagnostics, in vivo molecular imaging, and individualized treatments towards the personalization of cancer treatment. Cancer Theranostics describes the identification of novel biomarkers to advance molecular diagnostics of cancer. The book encompasses new molecular imaging probes and techniques for early detection of cancer, and describes molecular imaging-guided cancer therapy. Discussion also includes nanoplatforms incorporating both cancer imaging and therapeutic components, as well as clinical translation and future perspectives. Supports elimination of multi-step approaches and reduces delays in treatments through combinatorial diagnosis and therapy Fully assesses cancer theranostics across the emergent field, with discussion of biomarkers, molecular imaging, imaging guided therapy, nanotechnology, and personalized medicine Content bridges laboratory, clinic, and biotechnology industries to advance biomedical science and improve patient management

Nanomaterials for Tumor Targeting Theranostics

Nanomaterials for Tumor Targeting Theranostics Book
Author : Mingqian Tan,Aiguo Wu
Publisher : World Scientific
Release : 2016-02-22
ISBN : 981463543X
Language : En, Es, Fr & De

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Book Description :

Nanomaterials offer great potential for effective tumor diagnosis and therapy combing diagnostic agents and therapeutic drugs into one platform. In this book, the most recent progress of main nanomaterials and their applications in tumor targeting theranostics is presented. It summarizes the recent advances of current principal nanomaterials in tumor theranostics, including magnetic nanomaterials, quantum dots, mesoporous silica nanoparticles, gold nanomaterials, polymeric nanosystem, carbon nanomaterials, lipopolyplex nanoparticles, microbubbles, upconversion nanomaterials and dendrimers. It will enable readers to get a more realistic understanding of both the advantages and limitations of nanomaterials for potential tumor targeting theranosis. The publication of this book will accelerate the spread of ideas that are currently trickling through the scientific literature. Also a greater understanding of the potential and challenge of nanomaterials for tumor targeting theranostics is highly anticipated for practical clinical use. Contents:Nanomaterials as Therapeutic/Imaging Agent Delivery Vehicles for Tumor Targeting Theranostics (Mingqian Tan, Yanfang Wang, Xiaojie Song, and Yaqi Wu)Basics of Theranostics in Tumor (Huichao Zou, Yaohua Liu, and Shiguang Zhao)Magnetic Nanomaterials for Tumor Targeting Theranostics (Leyong Zeng, Zheyu Shen, and Aiguo Wu)Quantum Dots (QDs) for Tumor Targeting Theranostics (Yufei Ma, He Shen, Mengxin Zhang, and Zhijun Zhang)Mesoporous Silica Nanoparticles (MSNs) for Cancer Theranostics (Yu Hsia, Maharajan Sivasubramanian, Nai-Tzu Chen, and Leu-Wei Lo)Surface Enhanced Raman Scattering (SERS) Nanoprobes as Cancer Theranostics (Meikun Fan)Polymeric Nanosystems for Targeted Theranostics (Yongyong Li, Huiyun Wen, Haiqing Dong, Aijun Shen, Tianbin Ren, and Donglu Shi)Carbon Nanomaterials for Tumor Targeting Theranostics (João M M Leitão, Eliana F C Simões, and Joaquim C G Esteves da Silva)Lipopolyplex Nanoparticles for Tumor Targeting Theranostics (Fengying Dai and Xin Zhang)Microbubbles for Tumor Targeting Theranostics (Daming Yong, Xuejing Wang, Lei Wang, and Xiaojun Han)Upconversion Nanomaterials for Tumor Targeting Theranostics (Wei Wang)Functional Dendrimers as Nanoscale Theranostic Vehicles for Cancer Treatment (Kui Luo and Zhongwei Gu)Protein-based Nanoparticles for Tumor Targeting Theranostics (Yang Liu, Hao Wu, and Huihui Wang)Conclusions and Future Perspectives (Shanmin Gao and Narayan S Hosmane) Readership: Advanced undergraduates, graduate students, chemists, materials scientists, biomedical engineers, pharmacologists, biologists, doctors and oncologists in nanomaterials, nanobiotechnology, nanomedicine, tumor theranostics, tumor targeting, tumor diagnosis, tumor imaging, and tumor therapy. Key Features:One of the first books to comprehensively describe main nanomaterials for tumor targeting theranosticsFocuses on the combination of therapeutic and diagnostic applications of current principal nanomaterials, providing descriptions of cutting-edge discoveries along with perspectivesChapter contributors are internationally renowned scientists who are experts in their own research arena of nanomaterialsKeywords:Nanomaterials;Tumor Theranostics;Tumor Targeting;Tumor Diagnosis;Tumor Imaging;Tumor Therapy

Multifunctional Gold Nanostars for Cancer Theranostics

Multifunctional Gold Nanostars for Cancer Theranostics Book
Author : Yang Liu
Publisher : Springer
Release : 2018-03-15
ISBN : 331974920X
Language : En, Es, Fr & De

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Book Description :

This thesis presents the development of theranostic gold nanostars (GNS) for multimodality cancer imaging and therapy. Furthermore, it demonstrates that a novel two-pronged treatment, combining immune-checkpoint inhibition and GNS-mediated photothermal nanotherapy, can not only eradicate primary treated tumors but also trigger immune responses to treat distant untreated tumors in a mouse animal model. Cancer has become a significant threat to human health with more than eight million deaths each year, and novel methods for cancer management to improve patients’ overall survival are urgently needed. The developed multifunctional GNS nanoprobe with tip-enhanced plasmonics in the near-infrared region can be combined with (1) surface-enhanced Raman spectroscopy (SERS), (2) two-photon photoluminescence (TPL), (3) X-ray computed tomography (CT), (4) magnetic resonance imaging (MRI), (5) positron emission tomography (PET), and (6) photothermal therapy (PTT) for cancer imaging and treatment. The ability of the GNS nanoprobe to detect submillimeter intracranial brain tumors was demonstrated using PET scan – a superior non-invasive imaging modality – in a mouse animal model. In addition, delayed rechallenge with repeated cancer cell injection in cured mice did not lead to new tumor formation, indicating generation of a memorized immune response to cancer. The biocompatible gold nanostars with superior capabilities for cancer imaging and treatment have great potential for translational medicine applications.

Cancer Nanotheranostics

Cancer Nanotheranostics Book
Author : Muthupandian Saravanan,Hamed Barabadi
Publisher : Springer
Release : 2021-12-03
ISBN : 9783030762629
Language : En, Es, Fr & De

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Book Description :

Cancer Nanotheranostics, Volume 2 continues the discussion of the important work being done in this field of cancer nanotechnology. The contents of these two volumes are explained in detail as follows. In the first volume of Cancer Nanotheranostics, we discuss the role of different nanomaterials for cancer therapy including lipid-based nanomaterials, protein and peptide-based nanomaterials, polymer-based nanomaterials, metal-organic nanomaterials, porphyrin-based nanomaterials, metal-based nanomaterials, silica-based nanomaterials, exosome-based nanomaterials, and nano-antibodies. This important second volume discusses nano-based diagnosis of cancer, nano-oncology for clinical applications, nano-immunotherapy, nano-based photothermal cancer therapy, nanoerythrosomes for cancer drug delivery, regulatory perspectives of nanomaterials, limitations of cancer nanotheranostics, safety of nanobiomaterials for cancer nanotheranostics, multifunctional nanomaterials for targeting cancer nanotheranostics, and the role of artificial intelligence in cancer nanotheranostics. Volume 2 is a vital continuation of this two-volume set. Together, these two volumes create a comprehensive and unique examination of this important area of research.

Pulmonary Drug Delivery

Pulmonary Drug Delivery Book
Author : Ali Nokhodchi,Gary P. Martin
Publisher : John Wiley & Sons
Release : 2015-05-18
ISBN : 111879950X
Language : En, Es, Fr & De

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Book Description :

Drug therapy via inhalation route is at the cutting edge of modern drug delivery research. There has been significant progress on the understanding of drug therapy via inhalation products. However, there are still problems associated with their formulation design, including the interaction between the active pharmaceutical ingredient(s) (APIs), excipients and devices. This book seeks to cover some of the most pertinent issues and challenges of such formulation design associated with industrial production and desirable clinical outcome. The chapter topics have been selected with a view to integrating the factors that require consideration in the selection and design of device and formulation components which impact upon patient usability and clinical effectiveness. The challenges involved with the delivery of macromolecules by inhalation to both adult and pediatric patients are also covered. Written by leading international experts from both academia and industry, the book will help readers (formulation design scientists, researchers and post-graduate and specialized undergraduate students) develop a deep understanding of key aspects of inhalation formulations as well as detail ongoing challenges and advances associated with their development.

Nanoparticles in Cancer Therapy Novel Concepts Mechanisms and Applications

Nanoparticles in Cancer Therapy  Novel Concepts  Mechanisms and Applications Book
Author : Qingxin Mu,Bing Yan
Publisher : Frontiers Media SA
Release : 2019-04-03
ISBN : 2889458105
Language : En, Es, Fr & De

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Book Description :

Since the invention of nanomedicine decades ago, considerable progresses have been made, especially with cancer as a target. Nanoparticles have been proven to be powerful imaging tools or potent agents for cancer diagnosis, treatment and prevention. Active research spread from fundamental research to clinical investigations. This topic intends to cover several important aspects in this field including nanocarrier development, gene delivery, intrinsically active nanoparticles, tumor microenvironment, immunology, and toxicity.

Polymer Nanoparticles for Nanomedicines

Polymer Nanoparticles for Nanomedicines Book
Author : Christine Vauthier,Gilles Ponchel
Publisher : Springer
Release : 2017-01-07
ISBN : 3319414216
Language : En, Es, Fr & De

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Book Description :

This volume serves as a valuable handbook for the development of nanomedicines made of polymer nanoparticles because it provides researchers, students, and entrepreneurs with all the material necessary to begin their own projects in this field. Readers will find protocols to prepare polymer nanoparticles using different methods, since these are based on the variety of experiences that experts encounter in the field. In addition, complex topics such as, the optimal characterization of polymer nanoparticles is discussed, as well as practical guidelines on how to formulate polymer nanoparticles into nanomedicines, and how to modify the properties of nanoparticles to give them the different functionalities required to become an efficient nanomedicine for different clinical applications. The book also discusses the translation of technology from research to practice, considering aspects related to industrialization of preparation and aspects of regulatory and clinical development.

Nanomedicines for Breast Cancer Theranostics

Nanomedicines for Breast Cancer Theranostics Book
Author : Nanasaheb D. Thorat,Joanna Bauer
Publisher : Elsevier
Release : 2020-03-08
ISBN : 0128200170
Language : En, Es, Fr & De

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Book Description :

Nanomedicines for Breast Cancer Theranostics addresses the translational aspects and clinical perspectives of breast cancer nanomedicine from a multidisciplinary perspective. The book summarizes research efforts at the preclinical and clinical stage of nanostructures and nanomedicine for dealing with the important challenge of nanomedicine translation in breast cancer theranostics. This book is an important resource for those working in both academia and industry, focusing on hot topics in biomaterials, biomedical engineering, drug delivery and oncology. Shows how the discovery of new nanomedicines is leading directly to an increase in the early-stage diagnosis of breast cancer Includes coverage of breast cancer nanomedicine standardization and characterization, highlighting newly developed treatments, diagnostics and treatment monitoring tools Explains why the design of nanobiomaterials make them effective drug carriers when treating breast cancer

Nanoformulations in Human Health

Nanoformulations in Human Health Book
Author : Sushama Talegaonkar,Mahendra Rai
Publisher : Springer Nature
Release : 2020-07-31
ISBN : 3030418588
Language : En, Es, Fr & De

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Book Description :

This book is an amalgamation of knowledge, experience, and expertise in various aspects of nanotechnology, by experts who are proficient in designing of novel nanoformulations that are used in the treatment of various challenging and prevalent diseases. It is an exhaustive compilation of the multi-faceted arena of nanoformulations and the healthcare system that caters to the needs of academicians, scholars, researchers etc. The most important aspect of the book covers various types of nanoformulations and their applications in treatment of communicable and non-communicable diseases. Each chapter focuses on a particular nanoformulation as well as a disease including the pathophysiology of the disease, the current treatment modalities of diseases, the role of nanoformulation in treatment and other future aspects and directions for further work. Coverage includes neuropathic pain, colon targeting, nose-to-brain drug delivery, skin cancer, arthritis and tuberculosis.