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Motor Neuron Disorders And Related Diseases

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Motor Neuron Disorders and Related Diseases

Motor Neuron Disorders and Related Diseases Book
Author : Andrew Eisen,Pamela J. Shaw, MD
Publisher : Elsevier
Release : 2007-01-19
ISBN : 9780444518941
Language : En, Es, Fr & De

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Book Description :

This volume provides a comprehensive and scholarly accounting of motor neuron disorders, a group of diseases that are both clinically and genetically diverse. Clinicians and neuroscientists alike will find invaluable research and information on recent advancements that have occurred in the understanding of these disorders. From specific discussions of their underlying molecular pathogenesis, to advancements in therapies and diagnosis, users will find a resource that presents a comprehensive understanding of the general clinical features and management of these devastating disorders. In addition, new tactics that can be used to enhance patient care are also presented and discussed. Specific chapters within the volume include discussions pertaining to the historical aspects of motor neuron diseases, comparative anatomy, physiology, and development of the corticospinal system, and discussions of spinal muscular atrophies, amongst others. In addition, symptomatic therapy and the palliative aspects of clinical patient care are also presented. * A scholarly accounting of new research in motor neuron disorders and their associated diseases * The intricate relationships that exist between different motor neuron related disorders * A comprehensive resource that provides a guide to the diagnosis and treatment of motor neuron disorders, along with new approaches to patient care

Motor Neuron Disease

Motor Neuron Disease Book
Author : Kevin Talbot,Rachael Marsden,Rachel Botell
Publisher : Oxford University Press
Release : 2010
ISBN : 019954736X
Language : En, Es, Fr & De

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Book Description :

Written and designed to provide comprehensive, easily accessible advice for all healthcare professionals involved in the care of patients with this challenging condition, this book addresses the entire care pathway from presentation to diagnosis to symptom management and end of life issues.

Motor Neuron Diseases

Motor Neuron Diseases Book
Author : Leonard T. Kurland,Forbes Holten Norris
Publisher : Unknown
Release : 1966
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Motor Neuron Diseases book written by Leonard T. Kurland,Forbes Holten Norris, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Motor Neuron Disease

Motor Neuron Disease Book
Author : P.N. Leigh,Michael Swash
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 1447118715
Language : En, Es, Fr & De

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Book Description :

Here is the first book to provide a comprehensive overview of the clinical, pathological, and research aspects of motor neuron disease (MND). The text contains all essential features of the anatomy, physiology, pharmacology and toxicology of the motor system, a full description of MND and its variants, as well as historical developments and a review of the current concepts and controversies. This book comes at a time of increasing interest in neurodegenerative disorders and MND in particular. It will prove a key reference book with an integrated overview of the field, and will be indispensable to practicing neurologists, researchers, and all those with an interest in MND.

Greenfield s Neuropathology Two Volume Set

Greenfield s Neuropathology   Two Volume Set Book
Author : Seth Love,Arie Perry,James Ironside,Herbert Budka
Publisher : CRC Press
Release : 2018-10-08
ISBN : 1498729053
Language : En, Es, Fr & De

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Book Description :

Greenfield's Neuropathology, the world’s leading neuropathology reference, provides a comprehensive account of the pathological findings in neurological disease, their biological basis, and their clinical manifestations. The book’s detailed advice on pathological assessment and interpretation is based on clear descriptions of molecular and cellular processes and reactions that are relevant to the development of the nervous system, as well as its normal and abnormal functioning. The information is presented in an accessible way to readers working within a range of disciplines in the clinical neurosciences, and neuropathological findings are placed within the context of a broader diagnostic process. New for the Ninth Edition: Features online and downloadable digital formats with rapid search functions, annotation and bookmarking facilities, image collections, and live reference links Contains many color illustrations and high-quality clinical photographs to help with interpretation and understanding Includes more than 1000 new photographs and drawings Incorporates new design elements, such as alternate colour coding of chapters for easier navigation Known for its thorough yet practical approach, Greenfield's continues to provide trusted information to all neuropathologists and those in related specialties, including neurologists, neurosurgeons, general pathologists, neuroradiologists, and clinical neuroscientists.

Novel Aspects on Motor Neuron Disease

Novel Aspects on Motor Neuron Disease Book
Author : Humberto Foyaca Sibat,Lourdes de Fátima Ibañez-Valdés
Publisher : BoD – Books on Demand
Release : 2020-05-20
ISBN : 183880773X
Language : En, Es, Fr & De

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Book Description :

Dedicated to our readers, we include novel information (not reported in IntechOpen’s books before) about new contributions of aberrant astrocytes to MND damage and death in the SOD1G93A rat experimental model of ALS; novel genetic studies on ALS; an update of the structural and functional consequences of the spinal muscular atrophy-linked mutations of the survival motor neuron protein; stem cell therapy for MND; and the novel treatment for SMA and ALS in the introductory chapter. This book contains selected peer-reviewed chapters written by international researchers. In this publication, the readers will find a compilation of state-of-the-art reviews about etiology, therapies, investigations, the molecular basis of disease progression and clinical manifestations, and the genetic familial ALS, as well as novel therapeutic modalities. We look forward with confidence and pride to the remarkable role that this book will play for a new vision and mission.

Electromyography and Neuromuscular Disorders E Book

Electromyography and Neuromuscular Disorders E Book Book
Author : David C. Preston,Barbara E. Shapiro
Publisher : Elsevier Health Sciences
Release : 2012-11-01
ISBN : 1455744735
Language : En, Es, Fr & De

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Book Description :

Diagnose neuromuscular disorders more quickly and accurately with Electromyography and Neuromuscular Disorders: Clinical-Electrophysiologic Correlations, 3rd Edition! State-of-the-art guidance helps you correlate electromyographic and clinical findings and use the latest EMG techniques to their fullest potential. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Successfully correlate electrodiagnostic findings with key clinical findings for more confident diagnoses. Clearly see how to apply what you’ve learned with abundant case studies throughout the book. Obtain relevant clinical guidance quickly and easily with an accessible, easy-to-read writing style that’s both comprehensive and easy to understand. Ensure correct EMG needle placement and avoid neurovascular injuries by referring to more than 65 detailed, cross-sectional anatomy drawings. Diagnose many newly defined genetic neuromuscular conditions based on their electrodiagnostic presentation. Stay up to date with must-know information on iatrogenic complications of electrodiagnostic studies. Visualize key concepts more easily with a brand-new full-color design, new artwork, and new photographs. Access Electromyography and Neuromuscular Disorders online, fully searchable, at www.expertconsult.com, along with more than 70 videos that allow you to see and hear the EMG waveforms discussed in the text, as well as a convenient "test yourself" module.

Motor Neuron Disease An Issue of Neurologic Clinics

Motor Neuron Disease  An Issue of Neurologic Clinics  Book
Author : Richard J. Barohn
Publisher : Elsevier Health Sciences
Release : 2016-01-07
ISBN : 0323413455
Language : En, Es, Fr & De

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Book Description :

Dr. Richard Barohn and Dr. Mazen Dimachkie lead this publication on Motor Neuron Disease. Focus is on ALS, with inclusion of primary lateral sclerosis, primary muscular atrophy, leg amyotrophic diplegia, brachial amyotropic diplegia, and isolate bulbar ALS. Among the topics presented are. Patterns of weakness, classification of motor neuron disease & clinical diagnosis of sporadic ALS; Potential environmental factors in ALS; Neuropathology; Spinal muscular atrophy; Complementary and alternative therapies in ALS frontotemporal dysfunction and dementia in ALS; Symptoms management and end of life care; Research approaches to slowing progression of ALS; Familial ALS; Kennedy disease and more. Information in this issue presents: Description of the problem (Incidence, Prevalence, Severity, Natural history); 2. Review of pertinent data; Controversial areas discussing aspects such as areas of practice for which there are disagreements and why? What are the arguments and counter arguments and what data support them?; Conclusions using levels of clinical evidence that support or refute an intervention. Procedural steps are provided for diagnostic and treatment discussions along with clinical cases.

Motor Neuron Disease in Adults

Motor Neuron Disease in Adults Book
Author : Mark Bromberg
Publisher : Oxford University Press
Release : 2014-10-02
ISBN : 0199783160
Language : En, Es, Fr & De

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Book Description :

Motor Neuron Disease in Adults reviews new information as it applies to all aspects of motor neuron disease (ALS, PLS, PMA). The choice of articles is for those that use evidence-based methods to ensure that the new information is solid and advances the topic or issue. The book can be used by anyone who provides any type of care to ALS patients. In particular, neurologists will find the latest information on diagnosis and management, as well as new information on genetics and frontotemporal lobe involvement. Allied health providers will find useful information for their discipline. Patients will also find both specific and general information to help understand what they are experiencing and how to help manage their symptoms.

Motor Neurone Disease

Motor Neurone Disease Book
Author : Stuart Neilson,Frank Clifford Rose
Publisher : Class Publishing Ltd
Release : 2003
ISBN : 9781859590478
Language : En, Es, Fr & De

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Book Description :

"This essential guide is packed full of information about Motor Neurone Disease (MND) and how to deal with it. The book provides up-to-date information on a range of topics from diagnosis and treatment to adapting to life with MND including mobility, feelings, relationships, and much more. The authors address the physical and emotional upheaval for the person with MND and for the whole family, offering positive help and advice." - back cover.

Neuromuscular Disease Management and Rehabilitation Part I Diagnostic and Therapy Issues an Issue of Physical Medicine and Rehabilitation Clinics E Book

Neuromuscular Disease Management and Rehabilitation  Part I  Diagnostic and Therapy Issues  an Issue of Physical Medicine and Rehabilitation Clinics   E Book Book
Author : Nanette C. Joyce,Craig M. McDonald
Publisher : Elsevier Health Sciences
Release : 2012-09-16
ISBN : 145574784X
Language : En, Es, Fr & De

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Book Description :

Neuromuscular disease is a broad term that encompasses many diseases and ailments that either directly or indirectly impair the function of the body’s muscle system, via the nerves. This issue of PMR will provide an overview of current treatments and therapies for a variety of diseases. The GEs have gone through every issue published since 1998, and these 23 chapters will be meant to fill the numerous gaps in PMR’s coverage of the field over the past decade. The issue will include chapters on different treatment techniques, such as exercises, stretches, and nutrition. It will also provide chapters focusing on specific areas of the body, specific conditions, and an update on mobility technology for those with NMDs.

Multiple Sclerosis and Related Disorders

Multiple Sclerosis and Related Disorders Book
Author : Douglas S. Goodin
Publisher : Elsevier
Release : 2014-02-05
ISBN : 044463309X
Language : En, Es, Fr & De

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Book Description :

Multiple Sclerosis (MS) is generally understood to be an inflammatory autoimmune disease of the central nervous system. While we still are not certain of the root cause of MS, research results suggest that unknown environmental factors and the presence of specific genes seem the most probable targets. MS causes an inflammatory response in the central nervous system leading to neurodegeneration, oligodendrocyte death, axonal damage, and gliosis. Over the past five years ongoing research has greatly expanded our understanding of the pathogenesis of MS, detailed insight into the epidemiology and genetic factors related to MS, the introduction of new technologies and tests to better diagnose and predict the future course of the disease and the introduction of new treatments targeting MS. This collection of review chapters provides a comprehensive reference into the science and clinical applications of the latest Multiple Sclerosis research and will be a valuable resource for the neuroscience research community and the clinical neurology community of researchers and practitioners. A comprehensive tutorial reference detailing our current foundational understanding of Multiple Sclerosis Includes chapters on key topics including the genetics of MS, MRI imaging and MS, and the latest treatment options Each chapter is translational and focuses on current research and impact on diagnosis and treatment options

Neuromuscular Diseases

Neuromuscular Diseases Book
Author : Michael Swash,Martin S. Schwartz
Publisher : Springer Science & Business Media
Release : 2013-03-14
ISBN : 1447138341
Language : En, Es, Fr & De

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Book Description :

Nine years have elapsed since the second edition of this book was published. In this time the principal advances in neuromuscular diseases have been in the application of molecular genetics to understanding the aetiology and pathogenesis of this group of disorders. As a result many previously unrecognised disorders have been charac terised. Some clinical syndromes, such as the limb girdle dystrophies, have become better defined. In many such instances the new genetic information has led to major advances in knowledge of the biology of cell structures, for example, the membrane structural and channel proteins. The clinical syndromes themselves, and their patho logical and electrophysiological characteristics, however, remain as important as ever, since they constitute the clinical problem itself and, indeed, the database from which all other concepts emerge. Knowledge of the pathogenesis, genetics, and molecular biology of neuromuscular disorders is essential both in developing and applying new therapies and preventive measures, and in formulating genetic and prognostic advice. However, this informa tion does not necessarily always define clinically useful syndromes. Myotonia, for example, is an electrophysiological finding in some syndromes in which it is un detectable by clinical examination, although the phenomenon itself was originally defined as a clinical entity. The limb girdle muscular dystrophy syndromes can be defined by severity, distribution of weakness, age of onset, sex distribution and other characteristics and many of these can be better understood by study of the under lying defect in cell structural proteins.

Motor Neurone Disease

Motor Neurone Disease Book
Author : David Oliver
Publisher : SPCK
Release : 2012-03-30
ISBN : 1847091997
Language : En, Es, Fr & De

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Book Description :

Motor neurone disease (MND) is a progressive condition that damages the nervous system, leaving muscles wasted and weak, and causing loss of mobility, and difficulties with speech, swallowing and breathing. MND tends to affect people over 40 and is most common between the ages of 50 and 70. There are about 5,000 people with MND at any one time in the UK. The cause remains a mystery and there is no cure. The third edition of this book, which sells primarily via the Motor Neurone Disease Association, gives a full update of treatments and resources available to help those diagnosed live life to the full. Topics include what the disease is, what the doctors will do, and how to cope with the difficulties. This new edition also examines the latest on benefits, and up to date thinking on drug trials. Dr David Oliver, a leading expert on MND, shows how to treat not just the physical effects but also the emotional ones for the whole family. Dr Oliver also explains the vital role of the Motor Neurone Disease Association.

Motor Neuron Disease Research Progress

Motor Neuron Disease Research Progress Book
Author : Raffaele L. Mancini
Publisher : Nova Publishers
Release : 2008
ISBN : 9781604561555
Language : En, Es, Fr & De

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Book Description :

The motor neuron diseases (or motor neuron diseases) (MND) are a group of progressive neurological disorders that destroy motor neurons, the cells that control voluntary muscle activity such as speaking, walking, breathing, and swallowing. Neurological examination presents specific signs associated with upper and lower motor neuron degeneration. Signs of upper motor neuron damage include spasticity, brisk reflexes and the Babinski sign. Signs of lower motor neuron damage include weakness and muscle atrophy. Every muscle group in the body requires both upper and lower motor neurons to function. It is a common misconception that "upper" motor neurons control the arms, while "lower" motor neurons control the legs. The signs described above can occur in any muscle group, including the arms, legs, torso, and bulbar region. Symptoms usually present between the ages of 50-70, and include progressive weakness, muscle wasting, and muscle fasciculations; spasticity or stiffness in the arms and legs; and overactive tendon reflexes. Patients may present with symptoms as diverse as a dragging foot, unilateral muscle wasting in the hands, or slurred speech. This new book presents the latest research from around the globe.

Neurogenetics

Neurogenetics Book
Author : Stefan-M. Pulst
Publisher : Oxford University Press, USA
Release : 2000
ISBN : 9780195129755
Language : En, Es, Fr & De

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Book Description :

Neurogenetics is intended for any physician or scientist who manages patients with inherited diseases of the nervous system. It presents the clinical phenotypes of the most commonly inherited neurologic diseases, and their molecular pathogenesis, followed by a description of the appropriate tests to be used in diagnosis. Two introductory chapters familiarize the nongeneticist with medical genetic terminology and molecular genetic techniques useful in the analysis of genetic disease and genetic testing. Subsequent chapters examine major neurologic disorders caused by single defects, as well as disease phenotypes such as Alzheimer disease or amyotrophic lateral sclerosis which may be caused by defects in single genes, but may also be seen as sporadic diseases. The genetic components of other common neurologic disorders, such as epilepsy, multiple sclerosis, migraine, and stroke are all covered in detail. The final chapter discusses genetic counseling of symptomatic and pre-symptomatic individuals. Throughout, chapters discuss genotype/phenotype correlations and, where appropriate, animal models for inherited human neurologic diseases. Several chapters are devoted to recently discovered diseases caused by unstable DNA repeats. Special emphasis is placed on conveying how DNA testing can be applied to the daily practice of geneticists and neurologists.

Practical Guide to Neurogenetics

Practical Guide to Neurogenetics Book
Author : Thomas T. Warner,Simon R. Hammans
Publisher : Elsevier Health Sciences
Release : 2008-11-04
ISBN : 0702038458
Language : En, Es, Fr & De

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Book Description :

This simple guide to neurogenetics demystifies the overwhelming amount of information on the subject so you can identify key clinical features and understand your management options. Reach relevant differential diagnoses and provide appropriate counseling to your patients using the symptom-based approach. By integrating genetic and neurological approaches to diagnoses, this book ensures that the neurological consequences of a genetic diagnosis and the genetic consequences of a neurological diagnosis are clear and explicit. Concise and portable, this book is ideal for easy reference in clinical use. Details the underlying basic science and clinical features of genetic disorders by taking a symptom-based approach to provide you with a comprehensive understanding of the field. Focuses on the clinical application of neurogenetics to be of practical use to you in the clinic. Clarifies the neurological consequences of a genetic diagnosis and the genetic consequences of a neurological diagnosis by integrating genetic and neurological approaches to diagnoses. Discusses and evaluates necessary investigations so you know when to use them and when to refer. Highlights diagnostic and therapeutic tips so you can learn new concepts or refine your skills in practice. Refers to online sources, such as Online Mendelian Inheritance in Man (OMIM) and others, to help you supplement your knowledge.

Mechanisms of Clinical Signs E Book

Mechanisms of Clinical Signs   E Book Book
Author : Mark Dennis,William Talbot Bowen,Lucy Cho
Publisher : Elsevier Health Sciences
Release : 2012-01-27
ISBN : 072958075X
Language : En, Es, Fr & De

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Book Description :

The first consolidated textbook explaining the mechanism of clinical signs commonly seen in medicine. Mechanisms of Clinical Signs is the first consolidated text of its kind; designed to help medical students and junior doctors understand the pathophysiological mechanisms behind clinical signs. Unlike existing clinical examination textbooks which are predominantly organised by disease systems and states, Mechanisms of Clinical Signs is arranged by body system; bridging the gap between identifying clinical signs and understanding the causes behind them. Presented in a useful handbook style, Mechanisms of Clinical Signs discusses the evidence base and clinical value of each clinical sign to assist with interpretation. Examples are plentiful and include such signs as distinctive tremors in a Parkinson’s disease patient and red hands on a patient with liver disease. As well as being an easy-to-follow reference for clinical signs seen on the ward, Mechanisms of Clinical Signs is an excellent study aid – particularly useful for those preparing for ‘Viva’ or ‘OSCE’ practical stations. The ability to accurately identify and interpret clinical signs of disease upon examination is a vital first step in correct diagnosis and treatment. Mechanisms of Clinical Signs is therefore an essential textbook for medical students and new practitioners. Online StudentConsult resources accompany Mechanisms of Clinical Signs upon purchase. • first consolidated text explaining the mechanism of clinical signs commonly seen in medicine • easy reference guide for clinical signs seen on the ward or during examinations • a resource for those preparing for “Viva” or “OSCE” practical stations where students see patients and are asked specific questions relating to the clinical examination • organised by body system it reviews the common clinical signs seen in diseases by the main system or specialty of medicine in a convenient handbook style • each chapter contains all the clinical signs, a description of the sign, the disease/s in which the sign appears and an explanation as to the mechanism • evidence base and clinical value of the sign is discussed to assist interpretation • Online Student Consult resources accompany the text

Clinical Electromyography An Issue of Neurologic Clinics E Book

Clinical Electromyography  An Issue of Neurologic Clinics   E Book Book
Author : Devon I. Ruben
Publisher : Elsevier Health Sciences
Release : 2012-03-26
ISBN : 1455744174
Language : En, Es, Fr & De

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Book Description :

Electromyography remains a main diagnostic tool within neurology. This issue of Neurologic Clinics addresses the most recent developments in the clinical application of EMG. Articles in this issue include: Nerve conduction studies: Basic Concepts and Patterns of Abnormalities; Needle Electromyography–Basic Concepts andInterpretation of Recorded Potentials;Electrodiagnostic Evaluation of Carpal TunnelSyndrome;Electrodiagnostic Evaluation of Ulnar Neuropathyand Other Upper Extremity Mononeuropathy; Lower Extremity Mononeuropathies;Electrodiagnostic Evaluation of Brachial Plexopathies; Evaluation ofRadiculopathies;Electrodiagnostic Approach to Motor NeuronDiseases;Electrophysiologic Findings in PeripheralNeuropathies; Evaluation of Neuromuscular Junction Disorders in the EMGLaboratory;Electrodiagnostic Findings inMyopathy;Electrodiagnostic Approach to CranialNeuropathies; Technical Issues with Nerve Conduction Studies and Needle EMG;andCoding and Reimbursement of ElectrodiagnosticStudies.