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Monoclonal Antibodies

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Monoclonal Antibodies

Monoclonal Antibodies Book
Author : Anonim
Publisher : Unknown
Release : 1989
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Download Monoclonal Antibodies book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Use of Monoclonal Antibodies in Conditioning Regimen in Transplantation

Use of Monoclonal Antibodies in Conditioning Regimen in Transplantation Book
Author : Pervin Topcuoglu
Publisher : Unknown
Release : 2015
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Monoclonal antibodies (MoAbs) alone or in the combination of conventional therapies have been used in the treatment of many benign or malign diseases. In the transplantation setting, Moabs have been generally applied as a part of conditioning regimen in the aims of the prevention of graft versus host disease and/or graft failure or treatment of underlying hematologic disease. The most frequent used moAbs for this purpose are rituximab, alemtuzumab, Gemtuzumab Ozogamicin or radioimmunoconjugates. In this chapter, we discussed the role of moAbs use in the conditioning regimens of allogeneic or autologous stem cell transplantation.

Monoclonal Antibodies

Monoclonal Antibodies Book
Author : Philip Shepherd,Christopher J. Dean
Publisher : Practical Approach (Paperback)
Release : 2000
ISBN : 9780199637225
Language : En, Es, Fr & De

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Book Description :

Monoclonal Antibodies: A Practical Approach covers the preparation, testing, derivation, and applications of monoclonal antibodies. New immunological techniques incorporating tried and tested methodologies are described, making the book of interest to established and inexperienced immunologists. Both the standard somatic hybridization technique and recombinant techniques, including the use of phage libraries, for the preparation of rodent and human monoclonal antibodies are described. Protocols for both the small and large scale production are detailed, as well as purification and labelling (with both radioisotopes and non-radioisotopes) methods. The applications of monoclonal antibodies in immunoblotting, enzyme linked immunoassays, immunofluorescence, and FACS analysis are all covered in detail. Finally protocols are given for the use of monoclonal antibodies in rheumatoid arthritis, tissue typing, detecting DNA modified during chemotherapy, and in the clinical analysis of transplantation samples for malignancy. This book will therefore be an invaluable laboratory companion to anyone using monoclonal antibodies in their research.

Clinical Applications of Monoclonal Antibodies

Clinical Applications of Monoclonal Antibodies Book
Author : Ron Hubbard,Vincent Marks
Publisher : Springer Science & Business Media
Release : 2013-11-11
ISBN : 1461315735
Language : En, Es, Fr & De

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Book Description :

Immunology has come a long way in the hundred or so years since the general concepts were first enuciated by Metchnikoff, Ehrlich, Von Bebring and others, One of the landmarks in this progress was the invention and development of monoclonal antibody secreting hybridomas by Milstein and bis co-workers in Cambridge. Unlike most modern inventions of this importance that of monoclonal antibody production was made available to the scientific community tbroughout the world unimpeded by patent protection. This may explain tbe unusual rapidity witb which it has been applied to the benefit of mankind in general. This book, representing as it does the proceedings of tbe first International Symposium to be held on the clinical appli cations of monoclonal antibodies, shows just how much bas been achieved within the space of little more than a decade. The enormaus promise of monoclonal antibody technology, which became apparent soon after its discovery, has already progressed a long way towards fulfillment. The contributors to tbis volume, all of whom are actively engaged in monoclonal antibody development and application, represent the state of the art. Professor Vincent Marks V INTRODUCTION It has been some twelve years since the pioneering experiments of Köhler and Milstein led to the discovery of monoclonal antibodies. Single molecular species antiborlies with desired specificities could be produced by the fusion of antibody - producing cells with neoplastic cells.

Trends in Monoclonal Antibody Research

Trends in Monoclonal Antibody Research Book
Author : Marie A. Simmons
Publisher : Nova Publishers
Release : 2005
ISBN : 9781594545504
Language : En, Es, Fr & De

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Book Description :

This new and important international source of information brings together leading-edge research dedicated to monoclonal antibodies. Monoclonal antibodies (MABs) are: antibodies of exceptional purity and specificity; components of the immune system; able to recognise and bind to a specific antigen. Monoclonal antibodies are currently utilised in many diagnostic procedures, including: measuring protein and drug levels in serum; typing tissue and blood; identifying infectious agents; identifying clusters of differentiation for the classification and follow-up therapy of leukaemias and lymphomas; identifying tumour antigens and auto-antibodies; identifying the specific cells involved in the immune response; identifying and quantifying hormones. For example, monoclonal antibodies (MABs or MOABs) work on cancer cells in the same way natural antibodies work, by identifying and binding to the target cells. They then alert other cells in the immune system to the presence of the cancer cells. MABs are specific for a particular antigen-one designed for a B-cell lymphoma will not work on cells for ovarian cancer cells for example.

Production and Characterization of Monoclonal Antibodies Against Recombinant Fatty Acid Binding Protein of Fasciola Gigantica

Production and Characterization of Monoclonal Antibodies Against Recombinant Fatty Acid Binding Protein of Fasciola Gigantica Book
Author : Anuchittada Sirisriro,Mahāwitthayālai Mahidon,Mahāwitthayālai Mahidon. Khana Witthayāsāt
Publisher : Unknown
Release : 2001
ISBN : 9789746659697
Language : En, Es, Fr & De

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Book Description :

Download Production and Characterization of Monoclonal Antibodies Against Recombinant Fatty Acid Binding Protein of Fasciola Gigantica book written by Anuchittada Sirisriro,Mahāwitthayālai Mahidon,Mahāwitthayālai Mahidon. Khana Witthayāsāt, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Biomedical Index to PHS supported Research

Biomedical Index to PHS supported Research Book
Author : Anonim
Publisher : Unknown
Release : 1994
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Monoclonal Antibodies

Monoclonal Antibodies Book
Author : Maher Albitar
Publisher : Springer Science & Business Media
Release : 2007
ISBN : 1597453234
Language : En, Es, Fr & De

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Book Description :

Monoclonal Antibodies: Methods and Protocols examines a collection of state-of-the-art methods that employ monoclonal antibodies in a clinical setting with opening chapters focusing on the gold standard method for generating mouse monoclonal antibodies through hybridoma technology, future methods for engineering recombinant and humanized antibodies, methods for engineering soluble Fc fusion protein, and the use of antibodies and flow cytometry in the quantification of cell signaling proteins. Specific chapters describe how antibodies are used for the diagnosis and classification of hematologic diseases. Subsequent chapters examine the advantages and most recent advances of using bead-based immunoassays, including the ability of bead-based technology to multiplex and analyze several analytes simultaneously, and the use of beads in detecting fusion proteins resulting from chromosomal translocations. Concluding chapters provide additional examples of methodologies that employ monoclonal antibodies.

Research Awards Index

Research Awards Index Book
Author : Anonim
Publisher : Unknown
Release : 1987
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Cumulated Index Medicus

Cumulated Index Medicus Book
Author : Anonim
Publisher : Unknown
Release : 1986
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Biosimilars of Monoclonal Antibodies

Biosimilars of Monoclonal Antibodies Book
Author : Cheng Liu,K. John Morrow
Publisher : John Wiley & Sons
Release : 2016-12-19
ISBN : 1118662318
Language : En, Es, Fr & De

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Book Description :

Addressing a significant need by describing the science and process involved to develop biosimilars of monoclonal antibody (mAb) drugs, this book covers all aspects of biosimilar development: preclinical, clinical, regulatory, manufacturing. • Guides readers through the complex landscape involved with developing biosimilar versions of monoclonal antibody (mAb) drugs • Features flow charts, tables, and figures that clearly illustrate processes and makes the book comprehensible and accessible • Includes a review of FDA-approved mAb drugs as a quick reference to facts and useful information • Examines new technologies and strategies for improving biosimilar mAbs

Monoclonal Antibodies

Monoclonal Antibodies Book
Author : Johann H. Peters,Horst Baumgarten
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 3642745326
Language : En, Es, Fr & De

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Book Description :

The present new version of this popular laboratory manual is at the same time the first one of this text in the English language - and this makes me even a little proud, as it reminds me of probably the first collection of monoclonal recipes in English, written by myself, which circulated for a couple of years in many laboratories. In the meantime many researchers have put enormous effort into improving methods for monoclonal antibody production. The proce dures have become more and more standardized and by this have more and more lost the character of magic secrets. Hinrich Peters and Horst Baumgarten, who had followed this good tradition already in the previous edition, written in German, suc ceeded in making laboratory tricks teachable. They had contributed their own experiences in cell culture and immunology, and were able to engage a number of experienced authors to contribute to the work. They were all willing to follow the general concept of this book, which contains a brief theoretical background for the methods described and presents the procedures in a highly organized structure. So the book has retained its shape as a "cook-book", which I especially like.

Monoclonal Antibodies

Monoclonal Antibodies Book
Author : Satya N. Chatterjee
Publisher : Unknown
Release : 1985
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Monoclonal Antibodies in Tumor Therapy

Monoclonal Antibodies in Tumor Therapy Book
Author : H. H. Sedlacek
Publisher : Unknown
Release : 1988
ISBN : 9783805547635
Language : En, Es, Fr & De

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Book Description :

Download Monoclonal Antibodies in Tumor Therapy book written by H. H. Sedlacek, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Monoclonal Antibodies for Cancer Detection and Therapy

Monoclonal Antibodies for Cancer Detection and Therapy Book
Author : Robert William Baldwin,Vera S. Byers
Publisher : Unknown
Release : 1985
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Monoclonal Antibodies for Cancer Detection and Therapy book written by Robert William Baldwin,Vera S. Byers, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Monoclonal Antibodies in Endocrine Research

Monoclonal Antibodies in Endocrine Research Book
Author : Robert E. Fellows,George S. Eisenbarth
Publisher : Raven Press (ID)
Release : 1981
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Monoclonal Antibodies in Endocrine Research book written by Robert E. Fellows,George S. Eisenbarth, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Production and Characterization of Monoclonal Antibodies Directed Against Cell Surface Antigens of Canine Keratinocytes and Induction of Antibody mediated Lesions in Stratified Squamous Epithelium Using Monoclonal Antibodies

Production and Characterization of Monoclonal Antibodies Directed Against Cell Surface Antigens of Canine Keratinocytes and Induction of Antibody mediated Lesions in Stratified Squamous Epithelium Using Monoclonal Antibodies Book
Author : Maja M. Suter
Publisher : Unknown
Release : 1988
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Production and Characterization of Monoclonal Antibodies Directed Against Cell Surface Antigens of Canine Keratinocytes and Induction of Antibody mediated Lesions in Stratified Squamous Epithelium Using Monoclonal Antibodies book written by Maja M. Suter, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Purification and Study of Avian Retrovirus Proteins Using Monoclonal Antibodies

The Purification and Study of Avian Retrovirus Proteins Using Monoclonal Antibodies Book
Author : William McCrea Potts
Publisher : Unknown
Release : 1985
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Purification and Study of Avian Retrovirus Proteins Using Monoclonal Antibodies book written by William McCrea Potts, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Monoclonal Antibodies Against Bacteria

Monoclonal Antibodies Against Bacteria Book
Author : Alberto J. R. Macario
Publisher : Unknown
Release : 1985
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Monoclonal Antibodies against Bacteria, Volume I explores the generation, characterization, and utilization of monoclonal antibodies against bacteria and on other monoclonal products relevant to antibacterial immune responses. Organized into 12 chapters, this book begins with a discussion on monoclonal antibodies against bacteria, encompassing its scope, research, and directions. It shows that the coordinated use of antisera and panels of monoclonal antibodies is proving useful for classification as a diagnostic tool with prognostic implications in the case of pathogens, or as a preliminary st ...

Monoclonal Antibodies

Monoclonal Antibodies Book
Author : H. Zola
Publisher : Springer
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Monoclonal antibodies are highly specific reagents that play a crucial role in medical and biological research, and promise to yield major therapeutic advances. This book provides detailed coverage of the 'classical' methods of antibody production, including hybridization and cloning, and describes the latest techniques for genetically engineering antibodies and their derivatives. The major applications and the selection of the most appropriate anti-bodies for particular applications are also discussed.