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Molecular Sensors And Nanodevices

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Molecular Sensors and Nanodevices

Molecular Sensors and Nanodevices Book
Author : John X. J. Zhang,Kazunori Hoshino
Publisher : Academic Press
Release : 2018-11-19
ISBN : 0128148632
Language : En, Es, Fr & De

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Book Description :

Molecular Sensors and Nanodevices: Principles, Designs and Applications in Biomedical Engineering, Second Edition is designed to be used as a foundational text, aimed at graduates, advanced undergraduates, early-career engineers and clinicians. The book presents the essential principles of molecular sensors, including theories, fabrication techniques and reviews. In addition, important devices and recently, highly-cited research outcomes are also cited. This differentiates the book from other titles on the market whose primary focus is more research-oriented and aimed at more of a niche market. Covers the fundamental principles of device engineering and molecular sensing, sensor theories and applications in biomedical science and engineering Introduces nano/micro fabrication techniques, including MEMS, bioMEMS, microTAS and nanomaterials science that are essential in the miniaturization of versatile molecular sensors Explores applications of nanomaterials and biomaterials, including proteins, DNAs, nanoparticles, quantum dots, nanotubes/wires and graphene in biomedicine

Principles Designs and Applications in Biomedical Engineering

Principles  Designs and Applications in Biomedical Engineering Book
Author : Rebecca Cunningham
Publisher : Unknown
Release : 2014-12-18
ISBN : 9781505545395
Language : En, Es, Fr & De

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Book Description :

Nanotechnology ("nanotech") is the manipulation of matter on an atomic, molecular, and supramolecular scale. The earliest, widespread description of nanotechnology referred to the particular technological goal of precisely manipulating atoms and molecules for fabrication of macroscale products, also now referred to as molecular nanotechnology. A more generalized description of nanotechnology was subsequently established by the National Nanotechnology Initiative, which defines nanotechnology as the manipulation of matter with at least one dimension sized from 1 to 100 nanometers. This definition reflects the fact that quantum mechanical effects are important at this quantum-realm scale, and so the definition shifted from a particular technological goal to a research category inclusive of all types of research and technologies that deal with the special properties of matter that occur below the given size threshold. It is therefore common to see the plural form "nanotechnologies" as well as "nanoscale technologies" to refer to the broad range of research and applications whose common trait is size. Because of the variety of potential applications (including industrial and military), governments have invested billions of dollars in nanotechnology research. Through its National Nanotechnology Initiative, the USA has invested 3.7 billion dollars. The European Union has invested[when?] 1.2 billion and Japan 750 million dollars.

Theoretical experimental Molecular Engineering to Develop Nanodevices for Sensing Science

Theoretical experimental Molecular Engineering to Develop Nanodevices for Sensing Science Book
Author : Norma Lucia Rangel
Publisher : Unknown
Release : 2012
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Molecular electrostatic potentials (MEPs) and vibrational electronics ("vibronics") have developed into novel scenarios proposed by our group to process information at the molecular level. They along with the traditional current-voltage scenario can be used to design and develop molecular devices for the next generation electronics. Control and communication features of these scenarios strongly help in the production of "smart" devices able to take decisions and act autonomously in aggressive environments. In sensor science, the ultimate detector of an agent molecule is another molecule that can respond quickly and selectively among several agents. The purpose of this project is the design and development of molecular sensors based on the MEPs and vibronics scenarios to feature two different and distinguishable states of conductance, including a nano-micro interface to address and interconnect the output from the molecular world to standard micro-technologies. In this dissertation, theoretical calculations of the electrical properties such as the electron transport on molecular junctions are performed for the components of the sensor system. Proofs of concept experiments complement our analysis, which includes an electrical characterization of the devices and measurement of conductance states that may be useful for the sensing mechanism. In order to focus this work within the very broad array between nanoelectronic and molecular electronics, we define the new field of Molecular Engineering, which will have the mission to design molecular and atomistic devices and set them into useful systems. Our molecular engineering approach begins with a search for an optimum fit material to achieve the proposed goals; our published results suggest graphene as the best material to read signals from molecules, amplify the communication between molecular scenarios, and develop sensors of molecular agents with high sensitivity and selectivity. Specifically, this is possible in the case of sensors, thanks to the graphene atomic cross section (morphology), plasmonic surface (delocalized charge) and exceptional mechanical and electrical properties. Deliverables from this work are molecular devices and amplifiers able to read information encoded and processed at the molecular level and to amplify those signals to levels compatible with standard microelectronics. This design of molecular devices is a primordial step in the development of devices at the nanometer scale, which promises the next generation of sensors of chemical and biological agents molecularly sensitive, selective and intelligent.

Molecular Sensors and Nanodevices

Molecular Sensors and Nanodevices Book
Author : John X J Zhang,Kazunori Hoshino
Publisher : William Andrew
Release : 2013-12-03
ISBN : 1455776769
Language : En, Es, Fr & De

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Book Description :

With applications ranging from medical diagnostics to environmental monitoring, molecular sensors (also known as biosensors, chemical sensors, or chemosensors), along with emerging nanotechnologies offer not only valuable tools but also unlimited possibilities for engineers and scientists to explore the world. New generation of functional microsystems can be designed to provide a variety of small scale sensing, imaging and manipulation techniques to the fundamental building blocks of materials. This book provides comprehensive coverage of the current and emerging technologies of molecular sensing, explaining the principles of molecular sensor design and assessing the sensor types currently available. Having explained the basic sensor structures and sensing principles, the authors proceed to explain the role of nano/micro fabrication techniques in molecular sensors, including MEMS, BioMEMS, MicroTAS among others. The miniaturization of versatile molecular sensors opens up a new design paradigm and a range of novel biotechnologies, which is illustrated through case studies of groundbreaking applications in the life sciences and elsewhere. As well as the techniques and devices themselves, the authors also cover the critical issues of implantability, biocompatibility and the regulatory framework. The book is aimed at a broad audience of engineering professionals, life scientists and students working in the multidisciplinary area of biomedical engineering. It explains essential principles of electrical, chemical, optical and mechanical engineering as well as biomedical science, intended for readers with a variety of scientific backgrounds. In addition, it will be valuable for medical professionals and researchers. An online tutorial developed by the authors provides learning reinforcement for students and professionals alike. Reviews of state-of-the-art molecular sensors and nanotechnologies Explains principles of sensors and fundamental theories with homework problems at the end of each chapter to facilitate learning Demystifies the vertical integration from nanomaterials to devices design Covers practical applications the recent progress in state-of-the-art sensor technologies Includes case studies of important commercial products Covers the critical issues of implantability, biocompatibility and the regulatory framework

Micro Nano Cell and Molecular Sensors

Micro Nano Cell and Molecular Sensors Book
Author : Ping Wang,Chunsheng Wu,Ning Hu,K. Jimmy Hsia
Publisher : Springer
Release : 2016-12-01
ISBN : 9811016585
Language : En, Es, Fr & De

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Book Description :

This book focuses on cell- and molecule-based biosensors using micro/nano devices as transducers. After providing basic information on micro/nano cell- and molecule-based biosensors, it introduces readers to the basic structures and properties of micro/nano materials and their applications. The topics covered provide a comprehensive review of the current state of the art in micro/nano cell- and molecule-based biosensors as well as their future development trends, ensuring the book will be of great interest to the interdisciplinary community active in this area: researchers, engineers, biologists, medical scientists, and all those whose work involves related interdisciplinary research and applications. Dr. Ping Wang is a Professor in Department of Biomedical Engineering at Zhejiang University, Hangzhou, China. Dr. Chunsheng Wu is a Professor in Medical School at Xi’an Jiaotong University, Xi’an, China. Dr. Ning Hu is an Assistant researcher in Department of Biomedical Engineering at Zhejiang University and a Postdoctoral researcher in Medical School at Harvard University, Boston, USA. Dr. K. Jimmy Hsia is a Professor in Department of Biomedical Engineering at Carnegie Mellon University, Pittsburgh, USA.

Rapid and Cost effective Virus Detection Methods Using Molecular Sensors and Nano devices

Rapid and Cost effective Virus Detection Methods Using Molecular Sensors and Nano devices Book
Author : Lina Stella Franco
Publisher : Unknown
Release : 2016
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Accurate virus detection is important for diagnosis in a timely manner to facilitate rapid interventions and treatments. RNA viruses affect an extensive amount of the worlds population, particularly in tropical countries where emerging infectious agents often arise. Current diagnostic methods have three main problems: they are time consuming, typically not field-portable, and expensive. My research goal is to develop rapid, field-portable and cost sensitive diagnostic methods for RNA viruses. Herein, two different approaches to detect RNA viruses were proposed: Conjugated gold nanoparticles for detection of viral particles or virus-specific antibodies by monitoring changes in their optical properties, and Tentacle Probes coupled with qPCR for detection and differentiation of closely-related viral strains. The first approach was divided into two projects: the study and characterization of the gold nanoparticle-antibody system for detection of virus particles using dynamic light scattering (DLS) and UV-Vis spectrophotometry, and development of a detection method for antibodies using static light scattering (SLS) and antigen-conjugated gold nanoparticles. Bovine serum albumin (BSA) conjugated gold nanoparticles could successfully detect BSA-specific antibodies in vitro, and protein E from Dengue Virus serotype 2 conjugated gold nanoparticles could detect Dengue-specific antibodies, both in vitro and in serum samples. This method is more accurate than currently used detection methods such as dot blots. The second approach uses Tentacle Probes, which are modified molecular beacons, to detect with high specificity two different strains of Lymphocytic Choriomeningitis Virus (LCMV), Armstrong and Clone-13, which differ in only one nucleotide at the target sequence. We successfully designed and use Tentacle Probes for detection of both strains of LCMV, in vitro and in serum from infected mice. Moreover, detection of as little as 10% of Clone-13 strain was possible when diluted in 90% Armstrong strain. This approach enables the detection of different strains of virus even within a mixed quasispecies and may be important for improving intervention strategies for reducing disease. The detection methods provide rapid detection of viruses, including viral strains within mixed populations, and should enhance our ability in providing early responses to emerging infectious diseases due to RNA viruses including Zika or Dengue virus.

Nanodevices Principle and Applications

Nanodevices  Principle and Applications Book
Author : Jaysukh Markna,Tulshi Shiyani
Publisher : GRIN Verlag
Release : 2019-08-21
ISBN : 334600208X
Language : En, Es, Fr & De

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Book Description :

Academic Paper from the year 2018 in the subject Physics - Nuclear Physics, Molecular Physics, Solid State Physics, , language: English, abstract: This book can be useful for an academic course on nanoscience and nanotechnology. This book is very useful for the beginner in nanotechnology and nanoelectronics. The book is divided into seven chapters: The first chapter contains the introduction of nanodevices, definition and classification of nanostructures materials and nanodevices. The second chapter contains the detailed summary of the semiconductors and various semiconductor nanodevices. This will be helpful to study the changes occur at the nanoscale in bulk materials or bulk devices when they approach the nanoscale. The third chapter contains the introduction, principles, and applications of various quantum confined structures and devices. The fourth chapter gives the idea about the molecular junction, single molecular devices and their applications in other devices as an incorporated structures or hybrid applications. It contains the overview of natural and artificial nanodevices. It has given the knowledge of molecular nanoelectronics. The fifth chapter contains the overview and advanced knowledge of natural and artificial nanosensors. It explains the various nanosensors and their applications.

Molecular Imprinting for Nanosensors and Other Sensing Applications

Molecular Imprinting for Nanosensors and Other Sensing Applications Book
Author : Adil Denizli
Publisher : Elsevier
Release : 2021-01-29
ISBN : 0128221550
Language : En, Es, Fr & De

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Book Description :

Molecular Imprinting for Nanosensors and Other Sensing Applications provides fundamental knowledge on molecular imprinting, including types, preparation methods, properties and characterization techniques. The book also covers the state-of-the-art technological developments of sensors that incorporate with microfluidic systems, lab-on-a-chip-tools, and other techniques. Sections discuss the integration of molecularly imprinted polymers with current top-notch tools and platforms that facilitate their potential applications in the realms of medicine, pharmaceuticals and environmental monitoring. Topics of note include molecularly imprinted polymer-based sensor models, their functionalization methodologies, prominent characteristics, and their characterization tools. Covers, in an in-depth manner, molecular imprinting as it relates to nanosensors Provides an appropriate resource on the various applications of imprinted sensors, such as their use in the environment, medicine and food industry Includes future outlooks and expectations for sensor technology

Biosensors Based on Nanomaterials and Nanodevices

Biosensors Based on Nanomaterials and Nanodevices Book
Author : Jun Li,Nianqiang Wu
Publisher : CRC Press
Release : 2017-12-19
ISBN : 1466551526
Language : En, Es, Fr & De

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Book Description :

Biosensors Based on Nanomaterials and Nanodevices links interdisciplinary research from leading experts to provide graduate students, academics, researchers, and industry professionals alike with a comprehensive source for key advancements and future trends in nanostructured biosensor development. It describes the concepts, principles, materials, device fabrications, functions, system integrations, and applications of various types of biosensors based on signal transduction mechanisms, including fluorescence, photonic crystal, surface-enhanced Raman scattering, electrochemistry, electro-luminescence, field-effect transistor, and magnetic effect. The book: Explains how to utilize the unique properties of nanomaterials to construct nanostructured biosensors to achieve enhanced performance Features examples of biosensors based on both typical and emerging nanomaterials, such as gold nanoparticles, quantum dots, graphene, graphene oxides, magnetic nanoparticles, carbon nanotubes, inorganic nanowires/nanorods, plasmonic nanostructures, and photonic crystals Demonstrates the broad applications of nanostructured biosensors in environmental monitoring, food safety, industrial quality assurance, and in vitro and in vivo health diagnosis Inspires new ideas for tackling multiscale and multidisciplinary issues in developing high-performance biosensors for complex practical biomedical problems Focusing on the connection between nanomaterials research and biosensor development, Biosensors Based on Nanomaterials and Nanodevices illustrates the exciting possibilities and critical challenges of biosensors based on nanomaterials and nanodevices for future health monitoring, disease diagnosis, therapeutic treatments, and beyond.

Bionanoelectronics

Bionanoelectronics Book
Author : Daniela Dragoman,Mircea Dragoman
Publisher : Springer Science & Business Media
Release : 2012-03-22
ISBN : 3642255728
Language : En, Es, Fr & De

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Book Description :

This book presents the achievements in bionanoelectronics in a coherent manner. It deals with nanodevices applied to biostructures, molecular motors, molecular pumps, molecular nanoactuators and electronic biodevices, including nanodevices for sensing and imaging biomolcules. The book describes bionanoelectronics, detection of biomolecules and targets various biological applications such as detection and sequencing of DNA and early detection of various deseases and nanomedicine. Further important topics of the book are biomimetics and bioinspired electronics.The book also deals with biomolecules as building blocks of nanodevices for nanoelectronics or future computing architecture The application of scanning probe techniques to biological samples is described.

Energy Efficiency and Renewable Energy Through Nanotechnology

Energy Efficiency and Renewable Energy Through Nanotechnology Book
Author : Ling Zang
Publisher : Springer Science & Business Media
Release : 2011-09-06
ISBN : 9780857296382
Language : En, Es, Fr & De

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Book Description :

Reflecting the rapid growth of nanotechnology research and the potential impact of the growing energy crisis, Energy Efficiency and Renewable Energy Through Nanotechnology provides comprehensive coverage of cutting-edge research in the energy-related fields of nanoscience and nanotechnology, which aim to improve energy efficiency and the generation of renewable energy. Energy Efficiency and Renewable Energy Through Nanotechnology tightly correlates nanotechnology with energy issues in a general, comprehensive way that makes it not only suitable as a desk reference for research, but also as a knowledge resource for the non-expert general public. Readers will find Energy Efficiency and Renewable Energy Through Nanotechnology useful in a variety of ways, ranging from the creation of energy policy, to energy research development, and to education in nanotechnology and its application to energy-related problems. It can also be used as a primary or supplementary textbook for energy-related courses for advanced undergraduate and graduate students.

Outlook and Challenges of Nano Devices Sensors and MEMS

Outlook and Challenges of Nano Devices  Sensors  and MEMS Book
Author : Ting Li,Ziv Liu
Publisher : Springer
Release : 2017-02-22
ISBN : 3319508245
Language : En, Es, Fr & De

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Book Description :

This book provides readers with an overview of the design, fabrication, simulation, and reliability of nanoscale semiconductor devices, MEMS, and sensors, as they serve for realizing the next-generation internet of things. The authors focus on how the nanoscale structures interact with the electrical and/or optical performance, how to find optimal solutions to achieve the best outcome, how these apparatus can be designed via models and simulations, how to improve reliability, and what are the possible challenges and roadblocks moving forward.

Nanosensors and Nanodevices for Smart Multifunctional Textiles

Nanosensors and Nanodevices for Smart Multifunctional Textiles Book
Author : Andrea Ehrmann,Tuan Anh Nguyen,Phuong Nguyen Tri
Publisher : Elsevier
Release : 2020-09-16
ISBN : 0128209410
Language : En, Es, Fr & De

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Book Description :

Nanotechnology has been incorporated into a wide range of garments to improve the durability of clothing / apparel and create new properties for a special end-used application. It also incorporates wearable electronics into clothing to make it smarter. Smart nano-textiles refers to the uses and integration of smart nanocoatings, nanosensors and nanodevices in multifunctional textiles, since they are both low cost and have low power consumption. Various organic and inorganic nanomaterials can be used in garments to improve their properties and create new properties such as anti-bacterial, superhydrophobic, auto-cleaning, self-cleaning, stain repellent, wrinkle-free, static eliminating, fire resistant and electrically conductive properties. This book focuses on the fundamental concepts and approaches for the preparation of smart nanotextiles, their properties, and their applications in multifarious industries, including smart garments, biomedicine, construction/building materials, energy conversion/storage, automotive/aerospace industries and agriculture. Shows how nanotechnology is being used to be able to enhance textiles with smart properties, including anti-bacterial, superhydrophobic and auto-cleaning Explores which nanomaterial types are most compatible with particular textile classes Assesses the major challenges of integrating nanosensors and nanodevices into textiles

Nanotechnology in the Security Systems

Nanotechnology in the Security Systems Book
Author : Janez Bonča,Sergei Kruchinin
Publisher : Springer
Release : 2014-07-23
ISBN : 9401790051
Language : En, Es, Fr & De

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Book Description :

The topics discussed at the NATO Advanced Research Workshop “Nanotechnology in the Security Systems" included nanophysics, nanotechnology, nanomaterials, sensors, biosensors security systems, explosive detection. There have been many significant advances in the past two years and some entirely new directions of research are just opening up. Recent advances in nano science have demonstrated that fundamentally new physical phenomena are found when systems are reduced in size with dimensions, comparable to the fundamental microscopic length scales of the investigated material. Recent developments in nanotechnology and measurement techniques now allow experimental investigation of transport properties of nano devices. This work will be of interest to researchers working in spintronics, molecular electronics and quantum information processing.

Nanotechnology in Biology and Medicine

Nanotechnology in Biology and Medicine Book
Author : Tuan Vo-Dinh
Publisher : CRC Press
Release : 2017-10-03
ISBN : 1439893799
Language : En, Es, Fr & De

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Book Description :

The second edition of Nanotechnology in Biology and Medicine is intended to serve as an authoritative reference source for a broad audience involved in the research, teaching, learning, and practice of nanotechnology in life sciences. This technology, which is on the scale of molecules, has enabled the development of devices smaller and more efficient than anything currently available. To understand complex biological nanosystems at the cellular level, we urgently need to develop a next-generation nanotechnology tool kit. It is believed that the new advances in genetic engineering, genomics, proteomics, medicine, and biotechnology will depend on our mastering of nanotechnology in the coming decades. The integration of nanotechnology, material sciences, molecular biology, and medicine opens the possibility of detecting and manipulating atoms and molecules using nanodevices, which have the potential for a wide variety of biological research topics and medical uses at the cellular level. This book presents the most recent scientific and technological advances of nanotechnology for use in biology and medicine. Each chapter provides introductory material with an overview of the topic of interest; a description of methods, protocols, instrumentation, and applications; and a collection of published data with an extensive list of references for further details. The goal of this book is to provide a comprehensive overview of the most recent advances in instrumentation, methods, and applications in areas of nanobiotechnology, integrating interdisciplinary research and development of interest to scientists, engineers, manufacturers, teachers, and students.

Enabling Technology for MEMS and Nanodevices

Enabling Technology for MEMS and Nanodevices Book
Author : Henry Baltes,Oliver Brand,Gary K. Fedder,Christofer Hierold,Jan G. Korvink,Osamu Tabata
Publisher : John Wiley & Sons
Release : 2013-03-27
ISBN : 3527675043
Language : En, Es, Fr & De

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Book Description :

Microstructures, electronics, nanotechnology - these vast fields of research are growing together as the size gap narrows and many different materials are combined. Current research, engineering sucesses and newly commercialized products hint at the immense innovative potentials and future applications that open up once mankind controls shape and function from the atomic level right up to the visible world without any gaps. Sensor systems, microreactors, nanostructures, nanomachines, functional surfaces, integrated optics, displays, communications technology, biochips, human/machine interfaces, prosthetics, miniaturized medical and surgery equipment and many more opportunities are being explored. This new series, Advanced Micro & Nanosystems, provides cutting-edge reviews from top authors on technologies, devices and advanced systems from the micro and nano worlds.

Internet of Things Smart Spaces and Next Generation Networks and Systems

Internet of Things  Smart Spaces  and Next Generation Networks and Systems Book
Author : Olga Galinina,Sergey Andreev,Sergey Balandin,Yevgeni Koucheryavy
Publisher : Springer
Release : 2017-10-03
ISBN : 3319673807
Language : En, Es, Fr & De

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Book Description :

This book constitutes the joint refereed proceedings of the 17th International Conference on Next Generation Wired/Wireless Advanced Networks and Systems, NEW2AN 2017, the 10th Conference on Internet of Things and Smart Spaces, ruSMART 2017. The 71 revised full papers presented were carefully reviewed and selected from 202 submissions. The papers of NEW2AN focus on advanced wireless networking and applications; lower-layer communication enablers; novel and innovative approaches to performance and efficiency analysis of ad-hoc and machine-type systems; employed game-theoretical formulations, Markov chain models, and advanced queuing theory; grapheme and other emerging material, photonics and optics; generation and processing of signals; and business aspects. The ruSMART papers deal with fully-customized applications and services. The NsCC Workshop papers capture the current state-of-the-art in the field of molecular a nd nanoscale communications such as information, communication and network theoretical analysis of molecular and nanonetwork, mobility in molecular and nanonetworks; novel and practical communication protocols; routing schemes and architectures; design/engineering/evaluation of molecular and nonoscale communication systems; potential applications and interconnections to the Internet (e.g. the Internet of Nano Things).

Modeling and Control for Micro Nano Devices and Systems

Modeling and Control for Micro Nano Devices and Systems Book
Author : Ning Xi,Mingjun Zhang,Guangyong Li
Publisher : CRC Press
Release : 2017-12-19
ISBN : 1466554061
Language : En, Es, Fr & De

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Book Description :

Micro/nano-scale engineering—especially the design and implementation of ultra-fast and ultra-scale energy devices, sensors, and cellular and molecular systems—remains a daunting challenge. Modeling and control has played an essential role in many technological breakthroughs throughout the course of history. Therefore, the need for a practical guide to modeling and control for micro/nano-scale devices and systems has emerged. The first edited volume to address this rapidly growing field, Modeling and Control for Micro/Nano Devices and Systems gives control engineers, lab managers, high-tech researchers, and graduate students easy access to the expert contributors’ cutting-edge knowledge of micro/nanotechnology, energy, and bio-systems. The editors offer an integrated view from theory to practice, covering diverse topics ranging from micro/nano-scale sensors to energy devices and control of biology systems in cellular and molecular levels. The book also features numerous case studies for modeling of micro/nano devices and systems, and explains how the models can be used for control and optimization purposes. Readers benefit from learning the latest modeling techniques for micro/nano-scale devices and systems, and then applying those techniques to their own research and development efforts.

Carbon Nanotube Biosensors for Detection of Biomarkers in Breast Cancer Cells

Carbon Nanotube Biosensors for Detection of Biomarkers in Breast Cancer Cells Book
Author : Benjamin C. King
Publisher : Unknown
Release : 2012
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Detection and profiling of circulating tumor cells (CTCs) is useful for cancer screening and for managing treatment of carcinoma patients. Label-free technologies aim to accomplish detection rapidly with small, simple micro and nano devices. Carbon nanotubes are favorable molecular sensors due to their unique properties. They have been widely investigated for immunosensing of cancer biomarkers as free proteins, but very little has been done to detect biomarkers in intact cells and much remains to be understood regarding the mechanism of their sensing. We have developed a simple carbon nanotube biosensor for epithelial cell adhesion molecule (EpCAM) for sensing EpCAM positive cells. Sensor fabrication steps involving minimal air exposure were employed which reduced random noise upon sample introduction to the device. Optimized sensors recognized specific interactions with EpCAM positive MCF-7 cells and did not recognize EpCAM negative MCF-10A cells, producing the same characteristic signal as for blank phosphate buffered saline samples (no interaction). A two sample t-test found that the specific and nonspecific signals were significantly different, p = 0.0235. Specific binding signals are attributed to the combined binding events and negative cell membrane potential.

Nanoelectronics Nanowires Molecular Electronics and Nanodevices

Nanoelectronics  Nanowires  Molecular Electronics  and Nanodevices Book
Author : Krzysztof Iniewski
Publisher : McGraw Hill Professional
Release : 2010-08-22
ISBN : 0071664491
Language : En, Es, Fr & De

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Book Description :

The latest advances in nanoelectronics This definitive volume addresses the state of the art in nanoelectronics, covering nanowires, molecular electronics, and nanodevices. Written by global experts in the field, Nanoelectronics discusses cutting-edge techniques and emerging materials, such as carbon nanotubes and quantum dots. This pioneering work offers a comprehensive survey of nanofabrication options for use in next-generation technologies. Nanoelectronics covers: Electrical properties of metallic nanowires Electromigration defect nucleation in damascene copper interconnect lines Carbon nanotube interconnects in CMOS integrated circuits Printed organic electronics One-dimensional nanostructure-enabled chemical sensing Cross-section fabrication and analysis of nanoscale device structures and complex organic electronics Microfabrication and applications of nanoparticle-doped conductive polymers Single-electron conductivity in organic nanostructures for transistors and memories Synthesis of molecular bioelectronic nanostructures Nanostructured electrode materials for advanced Li-ion batteries Quantum-dot devices based on carbon nanotubes Carbon nanotubes as electromechanical actuators Low-level nanoscale electrical measurements and ESD Nanopackaging