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Molecular Pathology Of Pituitary Adenomas

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Molecular Pathology of Pituitary Adenomas

Molecular Pathology of Pituitary Adenomas Book
Author : Cristiana Tanase,Irina Ogrezeanu,Corin Badiu
Publisher : Elsevier
Release : 2011-10-31
ISBN : 0124158528
Language : En, Es, Fr & De

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Book Description :

The pituitary gland is an important one since it controls several of the other hormone glands, such as the thyroid and adrenals. A pituitary adenoma is an abnormal growth or tumor in this gland, and they are the subject of very active clinical and pathological research. This book examines the latest developments in this field and discusses the most important molecules implicated in apoptosis, angiogenesis and signal transduction. A good understanding of these processes is needed to identify the best therapies. Facilitates the understanding of the processes involved and how they are translated into therapy Illustrations are used to explain the complex mechanisms involved

Molecular Pathology of the Pituitary

Molecular Pathology of the Pituitary Book
Author : George Kontogeorgos
Publisher : Karger Medical and Scientific Publishers
Release : 2004-01-01
ISBN : 3805577400
Language : En, Es, Fr & De

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Book Description :

Molecular pathology, a newly emerging field of research, is providing a deeper insight and understanding of the pituitary structure and its function in health and disease. This volume covers the basic principles of molecular pathology and summarizes the current knowledge of pituitary development as well as pituitary adenoma morphology and pathogenesis. Molecular, state-of-the-art techniques currently used for research and clinical applications are presented and the results of these fascinating and sophisticated modern tools are illustrated. The contents cover topics such as the mechanisms involved in pituitary development and cytogenesis, tumor development and functional differentiation, cell death, the molecular cytogenetics of defective genes and chromosomes, and pituitary tumor formation and progression. The contributors all are internationally well-known and esteemed experts. The chapters are comprehensive and up to date and focus on recent advances and should stimulate further studies. The present volume of Frontiers of Hormone Research will be of particular interest not only to basic scientists, but also pathologists, clinical endocrinologists and neurosurgeons.

Molecular Pathology of Endocrine Diseases

Molecular Pathology of Endocrine Diseases Book
Author : Jennifer L. Hunt
Publisher : Springer Science & Business Media
Release : 2010-05-17
ISBN : 1441917071
Language : En, Es, Fr & De

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Book Description :

The past two decades have seen an ever accelerating growth in knowledge about molecular pathology of human diseases, which received a large boost with the sequencing of the human genome in 2003. Mole- lar diagnostics, molecular targeted therapy, and genetic therapy are now routine in many medical centers. The molecular field now impacts every field in medicine, whether clinical research or routine patient care. There is a great need for basic researchers to understand the potential clinical implications of their research whereas private practice clinicians of all types (general internal medicine and internal medicine specialists, medical oncologists, radiation oncologists, surgeons, pediatricians, family practitioners), clinical inves- gators, pathologists and medical laboratory directors, and radiologists require a basic understanding of the fundamentals of molecular pathogenesis, diagnosis, and treatment for their patients. Traditional textbooks in molecular biology deal with basic science and are not readily applicable to the medical setting. Most medical textbooks that include a mention of molecular pathology in the clinical setting are limited in scope and assume that the reader already has a working knowledge of the basic science of molecular biology. Other texts emphasize technology and testing procedures without integrating the clinical perspective. There is an urgent need for a text that fills the gap between basic science books and clinical practice.

Diagnosis and Management of Pituitary Tumors

Diagnosis and Management of Pituitary Tumors Book
Author : Kamal Thapar,Kalman Kovacs,Bernd Scheithauer,Ricardo V. Lloyd
Publisher : Springer Science & Business Media
Release : 2001
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Leading medical specialists and researchers have joined forces to create a comprehensive and authoritative reference text that addresses all aspects of pituitary tumors. They have included basic science topics such as the pathogenesis of pituitary tumors, their molecular biology and molecular pathology, and experimental models of pituitary tumorigenesis, as well as complete coverage of the medical diagnosis, therapy - including surgery - and management of these tumors. This book will immediately become the standard clinical reference.

Endocrine Pathology

Endocrine Pathology Book
Author : Ricardo V. Lloyd
Publisher : Springer Science & Business Media
Release : 2003-09-11
ISBN : 1592594034
Language : En, Es, Fr & De

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Book Description :

A comprehensive review of recent molecular discoveries that can clarify the pathophysiology of endocrine disease processes and contribute to the diagnostic aspects of endocrine pathology. Surgeons, medical oncologists, and radiation therapists discuss the treatment of endocrine disorders, especially tumors, with emphasis on differential diagnosis and on broadening the perspective that the endocrine pathologist must have in making specific tissue diagnoses. Of interest to practicing pathologists, pathology residents, endocrinologists, endocrinologists in training, veterinarians, and interested researchers.

Modern Neurosurgery of Meningiomas and Pituitary Adenomas

Modern Neurosurgery of Meningiomas and Pituitary Adenomas Book
Author : R. Fahlbusch,W.J. Bock,M. Brock,M. Buchfelder,M. Klinger
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 3709194504
Language : En, Es, Fr & De

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Book Description :

"Modem Neurosurgery of Meningiomas and Pituitary Adenomas" presents the state-of-the-art of neurosurgery for these two types of tumors. Following a classification of the pituitary adenomas according to pathology, molecular biological factors are presented and their effects evaluated as these aspects deepen our understanding of the growth and further expansion of these tumors. The diagnosis is made not only by a study of the hormonal status, but also by neuroradiology. A number of authors have devoted their efforts to the special problem groups such as the elderly patients and those with huge pituitary adenomas. Particular emphasis is of course placed on the surgical treatment, including transcranial and transphenoidal neurosurgery, but the use of medical treatment and irradiation must be discussed as well. The treatment of meningiomas has also been influenced by the molecular biology of hormone and growth factors. Therefore it is accorded extensive space in this volume. The prognostic significance of nuclear DNA content is discussed. Recent research with new diagnostic methods such as somatostatin scintigraphy, PET studies end progesterone receptor in tumor fragment spheroids is presented here. The treatment of these tumors, however, depends largely on their localization. For the neurosurgeon, the surgical treatment of meningiomas involving the cavernous sinus, meningiomas of the ventral Foramen of Monroe, meningiomas of the cerebello pontine angle and of the optic sheath is presented by prominent experienced leaders in this field.

Surgical Pathology of the Pituitary Gland

Surgical Pathology of the Pituitary Gland Book
Author : Ricardo V. Lloyd
Publisher : W B Saunders Company
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Intended for pathologists and endocrinologists, this book covers the diagnosis, surgical and medical treatment of pituitary adenomas. It includes special techniques used to study pituitary adenomas, including electron microscopy, cell culture and molecular biology. The text combines traditional morphologic approaches with more recent information derived from studies with the tools of the new biology. It combines extensive coverage of diagnosis with various aspects of the pituitary adenomas. The integrated approach provides a foundation for making specific diagnoses of pituitary disorders and also indicates the future directions of pituitary pathology. The emphasis is on diagnostic criteria for pituitary tumours. Chapters on medical and surgical management of pituitary adenomas provide a balanced perspective on the approach to the patient with pituitary tumours.

Endocrine Pathology

Endocrine Pathology  Book
Author : Ricardo V. Lloyd
Publisher : Springer Science & Business Media
Release : 2010-01-24
ISBN : 1441910697
Language : En, Es, Fr & De

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Book Description :

Endocrine Pathology: Differential Diagnosis and Molecular Advances, Second Edition provides detailed coverage of endocrine pathology with extensive discussion of the differential diagnosis as well as presentation of molecular pathobiology of the major endocrine organs. Revised and expanded from the first edition, each chapter, written by leaders in their respective field, has been updated with the latest advances that are transforming the field of endocrine pathology. Richly illustrated with color photomicrographs, useful diagrams and line drawings, each chapter includes differential diagnosis of common and uncommon lesions as well as material on molecular developments, with emphasis on the molecular findings that are most helpful in the diagnosis of specific disorders. Endocrine Pathology: Differential Diagnosis and Molecular Advances, Second Edition, provides a useful and well-organized resource designed not only for the endocrine pathologist and the general surgical pathologist, but also for the clinical endocrinologist and the endocrine surgeon.

Neuroendocrine Tumors Review of Pathology Molecular and Therapeutic Advances

Neuroendocrine Tumors  Review of Pathology  Molecular and Therapeutic Advances Book
Author : Aejaz Nasir,Domenico Coppola
Publisher : Springer
Release : 2016-08-31
ISBN : 1493934260
Language : En, Es, Fr & De

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Book Description :

This comprehensive subspecialty reference book on NeuroEndocrine Tumor (NET) pathology brings together the diagnostic and clinical expertise of an outstanding team of practicing neuroendocrine pathologists and oncologists. In addition to in-depth coverage of clinico-pathologic aspects of NETs of the various organ systems, the recent histological grading and staging schemes proposed by the North American and European NeuroEndocrine Tumor Societies (NANETS, ENETS), the World Health Organization (WHO) and the American Joint Committee on Cancer (AJCC), this book also focuses on the recent molecular and therapeutic advances in the field of NET pathology and oncology. Neuroendocrine Tumors: Review of Pathology, Molecular and Therapeutic Advances will be an essential reference book for anatomic pathology (histopathology) residents, fellows, surgical pathologists, researchers, oncologists, surgeons and other medical professionals practicing advanced NET Pathology and Oncology in academia, community, private practice and research settings.

Current Trends in Neuropathology An Issue of Surgical Pathology Clinics

Current Trends in Neuropathology  An Issue of Surgical Pathology Clinics Book
Author : David M. Meredith
Publisher : Elsevier Health Sciences
Release : 2020-06-04
ISBN : 0323756077
Language : En, Es, Fr & De

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Book Description :

This issue of Surgical Pathology Clinics will cover Current Trends in Neuropathology. Curated by Dr. David M. Meredith, this issue will explore topics in the field that are relevant for practicing clinicians. This issue is one of four selected each year by the series Consulting Editor, Jason L. Hornick. The volume will include articles on: Diversity in IDH-wildtype adult gliomas, pediatric gliomas, glioneuronal tumors, embryonal tumors, Molecular advances in tumors of the meninges, pituitary tumors, molecular diagnostics of CNS hematologic malignancies, Infectious diseases of the CNS, Iatrogenic neuropathology of systemic therapies, the future of neuropathology, the potential of digital image analysis and deep learning for CNS tumor diagnosis, and comparative evaluation of molecular and cytogenetic assays.

Molecular Pathology in Clinical Practice

Molecular Pathology in Clinical Practice Book
Author : Debra G.B. Leonard
Publisher : Springer Science & Business Media
Release : 2007-11-25
ISBN : 0387332278
Language : En, Es, Fr & De

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Book Description :

This authoritative textbook embodies the current standard in molecular testing for practicing pathologists, and residents and fellows in training. The text is organized into eight sections: genetics, inherited cancers, infectious disease, neoplastic hematopathology, solid tumors, HLA typing, identity testing, and laboratory management. Discussion of each diagnostic test includes its clinical significance, available assays, quality control and lab issues, interpretation, and reasons for testing. Coverage extends to HIV, hepatitis, developmental disorders, bioterrorism, warfare organisms, lymphomas, breast cancer and melanoma, forensics, parentage, and much more. Includes 189 illustrations, 45 in full-color. This textbook is a classic in the making and a must-have reference.

Molecular Pathology

Molecular Pathology Book
Author : John M. S. Bartlett,Abeer Shaaban,Fernando Schmitt
Publisher : Cambridge University Press
Release : 2016-03-01
ISBN : 1107443466
Language : En, Es, Fr & De

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Book Description :

Practical overview of current molecular techniques and their applications in each organ system, for practising and trainee pathologists.

Diagnosis and Management of Pituitary Tumors

Diagnosis and Management of Pituitary Tumors Book
Author : Kamal Thapar,Kalman Kovacs,Bernd Scheithauer,Ricardo V. Lloyd
Publisher : Springer Science & Business Media
Release : 2000-11-09
ISBN : 1592592171
Language : En, Es, Fr & De

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Book Description :

Eminent clinicians and specialists thoroughly review in great detail every aspect of pituitary tumors. The topics covered include prolactinomas, somatotroph adenomas, corticotroph adenomas, thyrotroph adenomas, nonfunctioning tumors, pituitary tumors, invasive adenomas, and pituitary carcinomas, as well as lesions, exclusive of pituitary adenomas, that occur in the sellar region. Also discussed are the new methods in endocrine diagnosis, high resolution imaging, receptor-mediated pharmacotherapy, microsurgical techniques, improved methods of radiation delivery, and the development of a precise and physiologically meaningful classification of pituitary tumors. Much-needed and brilliantly multidisciplinary, Diagnosis and Management of Pituitary Tumors offers all those dealing with pituitary cancer patients today's most comprehensive guide to diagnosis and treatment, one whose coordinated treatment strategies have sharply improved long-term survival rates for many patients.

Adenomas New Insights for the Healthcare Professional 2012 Edition

Adenomas  New Insights for the Healthcare Professional  2012 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2012-12-10
ISBN : 1464971390
Language : En, Es, Fr & De

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Book Description :

Adenomas: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Adenomas. The editors have built Adenomas: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Adenomas in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Adenomas: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Cushing s Disease

Cushing s Disease Book
Author : Brooke Swearingen,Beverly M. K. Biller
Publisher : Springer Science & Business Media
Release : 2011-09-08
ISBN : 9781461400110
Language : En, Es, Fr & De

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Book Description :

In Cushing’s Disease, leading authorities in the field offer a thorough review of the pathogenesis, diagnostic algorithm and treatment options for this complex disease. Beginning with a fascinating history of Cushing's disease that outlines its historical significance to both endocrinology and neurosurgery, the book goes onto to cover the full range of important issues, including the molecular pathogenesis of Cushing’s, anatomic pathology, the diagnosis of Cushing's syndrome, the differential of pseudo-Cushing's syndromes, hypercortisolemia, surgical removal of the corticotroph adenoma, post-operative management and assessment of remission, radiotherapeutic options, and the exciting developments in medical therapy. In addition, the book also addresses Cushing's disease in the pediatric population, given that its clinical manifestations and impact on growth can be severe; silent corticotroph adenomas as a distinct clinical entity; diagnosis and management of Cushing's disease during pregnancy, bilateral adrenalectomy, and, finally, the long-term psychological manifestations of hypercortisolemia. Comprehensive and an invaluable addition the literature, Cushing’s Disease is an essential reference for enhancing diagnosis and treatment of this debilitating disorder.

Atlas of Pediatric Brain Tumors

Atlas of Pediatric Brain Tumors Book
Author : Adekunle M. Adesina,Tarik Tihan,Christine E. Fuller,Tina Young Poussaint
Publisher : Springer Science & Business Media
Release : 2010-01-24
ISBN : 144191062X
Language : En, Es, Fr & De

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Book Description :

Recent evidence indicates that the physiology and response to various drugs in the pediatric population differs from that of the adult and must be appreciated to be able to fully address the health needs of the pediatric population. Atlas of Pediatric Brain Tumors covers areas ranging from neuroimaging, the use of crush and touch preps during introperative consultation, classic histological features of brain tumors, tumor variants, and a miscellaneous group of challenging tumors. Chapters consist of essential diagnostic information and features highlighting recognized variants and their differential diagnoses. A section on molecular pathology and electron microscopy is also included for each tumor category; along with a list of classic reviews and innovative articles on each of the tumor entities as suggested reading at the end of each chapter. Created to fill a void in the practice of pediatric neuropathology, this practical and well-illustrated Atlas of Pediatric Brain Tumors represents a collection of interesting, common and unusual tumors for a diagnostic exercise by the reader.

Pituitary Tumors

Pituitary Tumors Book
Author : Jürgen Honegger,Martin Reincke,Stephan Petersenn
Publisher : Academic Press
Release : 2021-04-11
ISBN : 0128199504
Language : En, Es, Fr & De

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Book Description :

Pituitary Tumors: A Comprehensive and Interdisciplinary Approach provides the latest information on preclinical issues, diagnostic procedures, treatment options and post-treatment care for patients with pituitary tumors. The book includes basic and advanced knowledge for a broad audience, including physicians, endocrinologists, neurosurgeons, neuro-radiologists, neuro-ophthalmologists, neuro-pathologists, oncologists, radiotherapists and researchers who are investigating pituitary tumors. Readers will find the latest research surrounding progress on uncoding the molecular mechanisms involved in tumor genesis. In addition, standard treatment modalities, including surgery, medical treatment and radiosurgery are explored. Provides state-of-the-art knowledge from experts who cover all specialties involved in the field of pituitary tumors Offers a comprehensive presentation of related issues to pituitary tumors Delivers a complete reference book for a broad audience, providing both basic and advanced knowledge

Adenomas New Insights for the Healthcare Professional 2013 Edition

Adenomas  New Insights for the Healthcare Professional  2013 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2013-07-22
ISBN : 1481656759
Language : En, Es, Fr & De

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Book Description :

Adenomas: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Adenomas: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Adenomas: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Textbook of Neurosurgery Third Edition Three Volume Set

Textbook of Neurosurgery  Third Edition  Three Volume Set Book
Author : Prakash Narain Tandon,Ravi Ramamurthi
Publisher : JP Medical Ltd
Release : 2012-04-01
ISBN : 9350250721
Language : En, Es, Fr & De

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Book Description :

This third edition is a comprehensive guide to Neurosurgery. Divided into three volumes, the textbook has been fully updated and includes 100 additional chapters covering recent advances in anatomy, physiology and differential diagnosis. With contributions from authors in the UK, USA, Canada, Middle East and South East Asia, this new edition covers a wide range of topics including history and diagnosis, spinal injuries, peripheral nerve, cranial and intracranial tumours, and vascular disorders. Packed with more than 1800 colour diagrams, illustrations and radiological images, the treatment of various neurosurgical subspecialties such as epilepsy and cerebral palsy, is also discussed.

Endoscopic Endonasal Transsphenoidal Surgery

Endoscopic Endonasal Transsphenoidal Surgery Book
Author : Enrico de Divitiis,Paolo Cappabianca
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 3709160847
Language : En, Es, Fr & De

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Book Description :

Currently, surgical management provides the definitive treatment of choice for most pituitary adenomas, craniopharyngiomas and meningiomas of the sellar region. The elegant minimally invasive transnasal endoscopic approach to the sella turcica and the anterior skull base has added a new dimension of versatility to pituitary surgery and can be adapted to many lesions in the region. In this multi-author book with numerous color illustrations the main aspects of the endonasal endoscopic approach to the skull base are presented, starting with a clear description of the endoscopic anatomy, the panoramic view afforded by the endoscope and the development of effective instruments and adjuncts. After the diagnostic studies, the strictly surgical features are considered in detail. The standard technique is described and particular aspects are treated, including the new extended approaches to the cavernous sinus, spheno-ethmoid planum and clival regions.