Skip to main content

Molecular Neurology

In Order to Read Online or Download Molecular Neurology Full eBooks in PDF, EPUB, Tuebl and Mobi you need to create a Free account. Get any books you like and read everywhere you want. Fast Download Speed ~ Commercial & Ad Free. We cannot guarantee that every book is in the library!

Molecular Neurology

Molecular Neurology Book
Author : Stephen Waxman
Publisher : Elsevier
Release : 2010-07-26
ISBN : 9780080546186
Language : En, Es, Fr & De

GET BOOK

Book Description :

Why a book on molecular neurology? Molecular neuroscience is advancing at a spectacular rate. As it does so, it is revealing important clues to the pathogenesis and pathophysiology of neurological diseases, and to the therapeutic targets that they present. Medicines work by targeting molecules. The more specific the targeting, the more specific the actions, and the fewer the side effects. Molecular Neurology highlights, for graduate and MD-PhD students, research fellows and research-oriented clinical fellows, and researchers in the neurosciences and other biomedical sciences, the principles underlying molecular medicine as related to neurology. Written by internationally recognized experts, this well-illustrated and well-referenced book presents the most up-to-date principles and disease examples relevant to molecular neurology, and reviews the concepts, strategies, and latest progress in this field. This book will interest anyone studying the molecular basis of neurology, or developing new therapies in neurology. Describes the newest molecular aspects of neurological disorders Provides an introduction to neurological disorders for basic scientists Updates clinicians and clinical researchers on the most recent developments

Rosenberg s Molecular and Genetic Basis of Neurological and Psychiatric Disease

Rosenberg s Molecular and Genetic Basis of Neurological and Psychiatric Disease Book
Author : Roger N. Rosenberg,Juan M. Pascual
Publisher : Elsevier
Release : 2014-10-28
ISBN : 0124105491
Language : En, Es, Fr & De

GET BOOK

Book Description :

Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Fifth Edition provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to the majority of neurologic and psychiatric disease. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the neuroscience and neurology research community. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling. Every chapter has been thoroughly revised or newly commissioned to reflect the latest scientific and medical advances by an international team of leading scientists and clinicians. The contents have been expanded to include disorders for which a genetic basis has been recently identified, together with abundant original illustrations that convey and clarify the key points of the text in an attractive, didactic format. Previous editions have established this book as the leading tutorial reference on neurogenetics. Researchers will find great value in the coverage of genomics, animal models and diagnostic methods along with a better understanding of the clinical implications. Clinicians will rely on the coverage of the basic science of neurogenetics and the methods for evaluating patients with biochemical abnormalities or gene mutations, including links to genetic testing for specific diseases. Comprehensive coverage of the neurogenetic foundation of neurological and psychiatric disease Detailed introduction to both clinical and basic research implications of molecular and genetic understanding of the brain Detailed coverage of genomics, animal models and diagnostic methods with new coverage of evaluating patients with biochemical abnormalities or gene mutations

Molecular Neurology

Molecular Neurology Book
Author : J. P. Schadé
Publisher : Unknown
Release : 1974
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Molecular Neurology book written by J. P. Schadé, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Neurogenetics in Neurology From Molecular Neuroscience to Precision Medicine

Neurogenetics in Neurology  From Molecular Neuroscience to Precision Medicine Book
Author : Matthew James Farrer,Guy Rouleau
Publisher : Frontiers Media SA
Release : 2020-12-22
ISBN : 2889662519
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Neurogenetics in Neurology From Molecular Neuroscience to Precision Medicine book written by Matthew James Farrer,Guy Rouleau, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

From Neuroscience to Neurology

From Neuroscience to Neurology Book
Author : Stephen Waxman
Publisher : Elsevier
Release : 2004-11-05
ISBN : 9780080506982
Language : En, Es, Fr & De

GET BOOK

Book Description :

The field of neurology is being transformed, from a therapeutically nihilistic discipline with few effective treatments, to a therapeutic specialty which offers new, effective treatments for disorders of the brain and spinal cord. This remarkable transformation has bridged neuroscience, molecular medicine, and clinical investigation, and represents a major triumph for biomedical research. This book, which contains chapters by more than 29 internationally recognized authorities who have made major contributions to neurotherapeutics, tells the stories of how new treatments for disabling disorders of the nervous system, such as stroke, multiple sclerosis, Parkinson’s disease, and migraine, were developed, and explores evolving themes and technologies that offer hope for even more effective treatments and ultimately cures for currently untreatable disorders of the brain and spinal cord. The first part of this book reviews the development of new therapies in neurology, from their inception in terms of basic science to their introduction into the clinical world. It also explores evolving themes and new technologies. This book will be of interest to everyone – clinicians and basic scientists alike – interested in diseases of the brain and spinal cord, and in the quest for new treatments for these disorders. * Presents the evolution of the field of neurology into a therapeutic discipline * Discusses lessons learned from past successes and applications to ongoing work * Explores the future of this field

Rosenberg s Molecular and Genetic Basis of Neurological and Psychiatric Disease

Rosenberg s Molecular and Genetic Basis of Neurological and Psychiatric Disease Book
Author : Roger N. Rosenberg,Juan M. Pascual
Publisher : Academic Press
Release : 2020-06
ISBN : 9780128139554
Language : En, Es, Fr & De

GET BOOK

Book Description :

Rosenberg's Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Sixth Edition: Volume One provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to neurologic and psychiatric disease. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the neuroscience and neurology research community. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling. Every chapter has been thoroughly revised or newly commissioned to reflect the latest scientific and medical advances by an international team of leading scientists and clinicians. The contents have been expanded to include disorders for which a genetic basis has been recently identified, together with abundant original illustrations that convey and clarify the key points of the text in an attractive, didactic format. Comprehensive coverage of the neurogenetic foundation of neurological and psychiatric disease Provides a detailed introduction on both the clinical and basic research implications of molecular and genetics surrounding the brain Includes new chapters on molecular genomics, CRISPR and the most recent updates in molecular genetics

Scientific American Molecular Neurology

Scientific American Molecular Neurology Book
Author : Joseph B. Martin,Scientific American, inc
Publisher : W. H. Freeman Trade
Release : 1998-01-01
ISBN : 9780894540301
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Scientific American Molecular Neurology book written by Joseph B. Martin,Scientific American, inc, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Molecular Neuropharmacology A Foundation for Clinical Neuroscience Third Edition

Molecular Neuropharmacology  A Foundation for Clinical Neuroscience  Third Edition Book
Author : Eric J. Nestler,Steven E. Hyman,Robert C. Malenka
Publisher : McGraw Hill Professional
Release : 2015-03-22
ISBN : 0071827706
Language : En, Es, Fr & De

GET BOOK

Book Description :

GAIN A COMPLETE UNDERSTANDING OF NERVOUS SYSTEM FUNCTION AND ITS RELATIONSHIP TO HUMAN NEUROLOGIC DISORDERS Molecular Neuropharmacology first reviews the fundamental biochemistry of the functioning nervous system and then describes how nerve cells communicate with one another through numerous types of neurotransmitters involving amino acids, monoamines, neuropeptides, and neurotrophic factors, among several others. The neuropharmacology and neural circuits that underlie complex behaviors as well as major neural disorders are also discussed as are the drugs used to treat those conditions. In the final section, the authors use the concepts presented in the first two sections to explain how irregularities in the biochemistry of neuronal interactions can lead to a wide array of clinical manifestations. FEATURES NEW chapter on neuroinflammation All chemical structure illustrations have been redrawn and improved Fully updated to reflect the latest breakthroughs and new drugs The most well-written and easily understood work on the subject More than 300 full-color illustrations!

Molecular Mechanisms of Dementia

Molecular Mechanisms of Dementia Book
Author : Wilma Wasco,Rudolph Tanzi
Publisher : Springer Science & Business Media
Release : 1996-11-01
ISBN : 1592594719
Language : En, Es, Fr & De

GET BOOK

Book Description :

The past decade has witnessed a revolution in the attempts of scientists to under stand the molecular basis of dementia. Although dementia, as defined by global cogni tive decline involving gradual loss of memory, reasoning, judgment, and orientation, presents most commonly in the form of Alzheimer's disease (AD), an assortment of other less common disorders, such as prion and Pick's disease, can also lead to symp toms that are similar to those observed in patients with AD. The primary goal of Molecular Mechanisms of Dementia is to address the various mechanisms and multi faceted approaches currently being employed to more clearly delineate the etiological and pathogenic events responsible for the onset of dementia. Perhaps the greatest boon to obtaining a clearer understanding of the causes of AD has come from genetic and molecular biological studies carried out over the past decade. At the genetic level, it has become increasingly clear that AD is a heteroge neous disorder that can be broadly classified into two categories. "Late onset" (>60 yr) cases, which account for the vast majority of AD, genetically involve "susceptibility" genes representing risk factors for the disease (e. g. , inheritance of the 84 allele of the Apolipoprotein E gene). In many cases, the susceptibility gene can act as a "modifier" that modulates the pathogenic cascade occurring subsequent to a separate etiological event "initiating" or "causing" the disorder.

Scientific American Molecular Neurology

Scientific American Molecular Neurology Book
Author : Joseph B. Martin
Publisher : Unknown
Release : 1998
ISBN : 9780894540288
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Scientific American Molecular Neurology book written by Joseph B. Martin, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Molecular Biology of Neurological Disease

The Molecular Biology of Neurological Disease Book
Author : Roger N. Rosenberg,A. E. Harding
Publisher : Butterworth-Heinemann
Release : 2013-10-22
ISBN : 148316330X
Language : En, Es, Fr & De

GET BOOK

Book Description :

The Molecular Biology of Neurological Disease reviews advances that have been made in understanding the molecular mechanisms of neurological disorders as well as immediate and future applications of molecular biological techniques to clinical practice. This book explores the molecular genetics of neurological disease such as muscular dystrophy, Joseph disease, and Huntington's disease, along with the mitochondrial genes implicated in such conditions. This text is comprised of 18 chapters and begins by introducing the reader to the basic principles and methods of molecular genetic techniques used in the diagnosis of neurological disease. Attention then turns to several aspects of genetic expression in the brain, including the extent to which the genome is expressed in the brain. The next chapter focuses on the visualization of polyadenylated messenger RNAs in individual cells in mammalian brain using in situ hybridization techniques, combined with immunohistochemical localization of specific proteins and neuropeptides implicated in diseases such as Alzheimer dementia. This book also discusses the molecular biology of chemical synaptic neurotransmission; proteins involved in the regulation of nervous system development; and gene expression in skeletal muscle. This text then concludes with a summary of the ""neurological gene map"" as it stands in the latter part of 1987. This book is intended for physicians who grapple with the problems of neurological disorders on a daily basis, including neurologists, neurologists in training, and those in related fields such as neurosurgery, internal medicine, psychiatry, and rehabilitation medicine.

Rosenberg s Molecular and Genetic Basis of Neurological and Psychiatric Disease

Rosenberg s Molecular and Genetic Basis of Neurological and Psychiatric Disease Book
Author : Roger N. Rosenberg,Juan M. Pascual
Publisher : Academic Press
Release : 2020-06-24
ISBN : 012813867X
Language : En, Es, Fr & De

GET BOOK

Book Description :

Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Sixth Edition: Volume Two provides a comprehensive introduction and reference to the foundations and practical aspects relevant to the majority of neurologic and psychiatric disease. This updated volume focuses on degenerative disorders, movement disorders, neuro-oncology, neurocutaneous disorders, epilepsy, white matter diseases, neuropathies and neuronopathies, muscle and neuromuscular junction disorders, stroke, psychiatric disease, and a neurologic gene map. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands on the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, related professionals, and for the neuroscience and neurology research community at large. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling. Provides comprehensive coverage on the neurogenetic foundation of neurological and psychiatric disease Presents detailed coverage of genomics, animal models and diagnostic methods, with new coverage on evaluating patients with biochemical abnormalities or gene mutations Includes new chapters on the pharmacogenomics of epilepsy and the most recent updates in molecular genetics, focusing on neurodegenerative and psychiatric diseases

Molecular Basis of Neurological Disorders and Their Treatment

Molecular Basis of Neurological Disorders and Their Treatment Book
Author : J.W. Gorrod,A. Albano,E. Ferrari,S. Papa
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 9401131147
Language : En, Es, Fr & De

GET BOOK

Book Description :

cytochemical techniques (ICC) which provide a useful adjunct to investigations by immunoblotting. A particular advantage of a cytochemical approach to the investiga tion of mitochondrial disorders is that it allows the mosaic distribution of certain of these defects to be detected, whereas the tissue homogeniza tion involved in conventional enzyme assays or immunoblotting precludes this. A further advantage of MEA or ICC is that only small amounts of tissue are needed, which is important since many of the affected patients are infants or small children. The main aim of this communica tion is to outline ways in which these techniques can be used in the diagnosis and further investigation of mitochondrial disorders. Reference will be made not only to those situations in which MEA and ICC offer advantages over standard enzyme asays and immunoblotting but also to contexts in which the reverse applies. 4. 2 MATERIALS AND METHODS Muscle biopsies for cytochemical investigation were snap-frozen using isopentane cooled to - 150°C in liquid nitrogen. Samples were stored in heat-sealed polythene packets in the vapour phase of liquid nitrogen containers. 4. 2. 1 Microphotometric enzyme assays Frozen sections 8 Jlm thick were cut using a Reichert-J ung Frigocut cryostat microtome equipped with motor-driven cutting action to maintain maximal reproducibility of section thickness. Sections were picked up on microscope slides and air-dried for 15 min at room temperature.

Molecular Physiology and Metabolism of the Nervous System

Molecular Physiology and Metabolism of the Nervous System Book
Author : Gary A. Rosenberg
Publisher : OUP USA
Release : 2012-04-30
ISBN : 0195394275
Language : En, Es, Fr & De

GET BOOK

Book Description :

Molecular Physiology and Metabolism of the Nervous System, authored by Gary A. Rosenberg, an authority on the physiology of brain fluids and metabolism, combines the classic physiology that dates back to the beginning of the nineteenth century with the advances in molecular sciences, providing a strong framework for understanding the diseases that are commonly treated by neurologists.

Molecular Biology of Neurodegenerative Diseases Visions for the Future

Molecular Biology of Neurodegenerative Diseases  Visions for the Future Book
Author : Anonim
Publisher : Academic Press
Release : 2019-11-05
ISBN : 0128178752
Language : En, Es, Fr & De

GET BOOK

Book Description :

Molecular Biology of Neurodegenerative Diseases: Visions for the Future, Volume 168 in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. The series includes in-depth knowledge on the molecular biological aspects of organismal physiology, with this release including chapters on Alzheimer's disease, Prion-like propagation of alpha-synuclein, What - if anything - can we learn about neurodegenerative diseases from yeast?, Mitochondrial rejuvenation and replacement as a novel strategy for treatment of age-related neurodegenerative diseases, Propagation and removal of cerebral amyloid angiopathy, and much more. Includes comprehensive coverage of molecular biology Presents ample use of tables, diagrams, schemata and color figures to enhance the reader's ability to rapidly grasp the information provided Contains contributions from renowned experts in the field

Neuroscience for Neurologists

Neuroscience for Neurologists Book
Author : Patrick F. Chinnery
Publisher : Imperial College Press
Release : 2006
ISBN : 1860948960
Language : En, Es, Fr & De

GET BOOK

Book Description :

The last decade has seen major advances in our understanding of the basic scientific principles that underpin clinical neurology. Many of these advances have already had a major impact on routine clinical practice, and this is likely to continue in the future. Although this makes it an exciting time to practice neurology, it also presents new challenges. How can established general neurologists keep up-to-date with clinically relevant scientific advances, and how can the specialist remain competent outside his own field? What should trainee neurologists learn to prepare themselves for the future career?. Written by experts in the field, this timely book presents the scientific principles behind neurology. It aims to take the reader from the human genome, through gene expression, to molecular and cellular pathology, and subsequently to contemporary clinical investigations and clinical trials. Each contribution includes a discussion about the future of the field and highlights areas of potential growth and their relevance to routine clinical practice over the next decade. The succinctly written chapters will be easily accessible to both neurologists and trainees who have no expertise in the area. Many of the chapters are co-written by a clinician and a basic scientist, and each has been subject to peer review OCo both by experts in the field and a OC jobbingOCO general neurologist. This has ensured that the contributions reflect contemporary scientific thinking which is presented in a way that is easy to digest. The book includes generous use of diagrams to help explain difficult concepts, a glossary explaining the terminology, and provides information on links to web-based resources for further information. Sample Chapter(s). Chapter 1: Neurogenetics -- Single Gene Disorders (761 KB). Contents: Neurogenetics OCo Single Gene Disorders; Neurogenetics II: Complex Disorders; Functional Genomics and Proteomics: Application in Neurosciences; Mitochondria; Nanotechnology for Neuronal Ion Channels; Molecular and Cellular Pathways of Neurodegeneration in Motor Neurone Disease; Neurodegenerative Disorders: Parkinson''s Disease and Huntington''s Disease; Molecular Pathogenesis of Neuroinflammation; Neurovirology; Molecular Neurology of Prion Disease; Monitoring and Interpretation of Intracranial Pressure; Cerebral Perfusion and Stroke; A Review of Structural Magnetic Resonance Neuroimaging; Applications of Positron Emission Tomography (PET) in Neurology; Functional Magnetic Resonance Imaging; How to Spot Bias and Other Potential Problems in Randomised Controlled Trials. Readership: Neurologists, trainees/interns in neurology and related disciplines, neurobiologists."

Cellular and Molecular Methods in Neuroscience Research

Cellular and Molecular Methods in Neuroscience Research Book
Author : Adalberto Merighi,Giorgio Carmignoto
Publisher : Springer Science & Business Media
Release : 2007-12-14
ISBN : 0387224602
Language : En, Es, Fr & De

GET BOOK

Book Description :

There are numerous books on cellular and molecular protocols for general use in cell biology but very few are exclusively devoted to neurobiology. This book fills this gap and explains in a clear and consistent manner, some of the more commonly used protocols in neuroscience research. Each chapter is written by either the person who invented the procedure or an expert in the field. The format is uniform: "Overview," "Background," "Protocols," and "results and discussion." Each protocol begins with the principle of the technique, studies in cell culture, materials and reagents, and, lastly, step-by-step outline of the procedure itself. This highly practical book is also well illustrated (with 17 four color plates) to make the concepts and procedures easy to understand and perform.

Molecular Neurobiology in Neurology and Psychiatry

Molecular Neurobiology in Neurology and Psychiatry Book
Author : Eric R. Kandel
Publisher : Lippincott Williams & Wilkins
Release : 1987
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Molecular Neurobiology in Neurology and Psychiatry book written by Eric R. Kandel, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Clinical Companion to the Molecular and Genetic Basis of Neurological Disease

Clinical Companion to the Molecular and Genetic Basis of Neurological Disease Book
Author : Roger N. Rosenberg,Stanley B. Prusiner,Salvatore DiMauro
Publisher : Unknown
Release : 1998
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

"To create this companion volume, the editors have extracted from the original book the practical and clinical information that is most useful for neurologists in the diagnosis and treatment of genetic neurologic disease."--Preface.

The Molecular and Cellular Basis of Neurodegenerative Diseases

The Molecular and Cellular Basis of Neurodegenerative Diseases Book
Author : Michael S. Wolfe
Publisher : Academic Press
Release : 2018-03-29
ISBN : 0128113057
Language : En, Es, Fr & De

GET BOOK

Book Description :

The Molecular and Cellular Basis of Neurodegenerative Diseases: Underlying Mechanisms presents the pathology, genetics, biochemistry and cell biology of the major human neurodegenerative diseases, including Alzheimer’s, Parkinson’s, frontotemporal dementia, ALS, Huntington’s, and prion diseases. Edited and authored by internationally recognized leaders in the field, the book's chapters explore their pathogenic commonalities and differences, also including discussions of animal models and prospects for therapeutics. Diseases are presented first, with common mechanisms later. Individual chapters discuss each major neurodegenerative disease, integrating this information to offer multiple molecular and cellular mechanisms that diseases may have in common. This book provides readers with a timely update on this rapidly advancing area of investigation, presenting an invaluable resource for researchers in the field. Covers the spectrum of neurodegenerative diseases and their complex genetic, pathological, biochemical and cellular features Focuses on leading hypotheses regarding the biochemical and cellular dysfunctions that cause neurodegeneration Details features, advantages and limitations of animal models, as well as prospects for therapeutic development Authored by internationally recognized leaders in the field Includes illustrations that help clarify and consolidate complex concepts