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Molecular Medicine

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Clinical Molecular Medicine

Clinical Molecular Medicine Book
Author : Dhavendra Kumar
Publisher : Academic Press
Release : 2019-11-30
ISBN : 0128094427
Language : En, Es, Fr & De

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Book Description :

Clinical Molecular Medicine: Principles and Practice presents the latest scientific advances in molecular and cellular biology, including the development of new and effective drug and biological therapies and diagnostic methods. The book provides medical and biomedical students and researchers with a clear and clinically relevant understanding on the molecular basis of human disease. With an increased focus on new practice concepts, such as stratified, personalized and precision medicine, this book is a valuable and much-needed resource that unites the core principles of molecular biology with the latest and most promising genomic advances. Illustrates the fundamental principles and therapeutic applications of molecular and cellular biology Offers a clinically focused account of molecular heterogeneity Includes comprehensive coverage of many different disorders, including growth and development, cardiovascular, metabolic, skin, blood, digestive, inflammatory, neuropsychiatric disorders, and many more

Molecular Medicine

Molecular Medicine Book
Author : R. Trent
Publisher : Academic Press
Release : 2012-08-17
ISBN : 0123814510
Language : En, Es, Fr & De

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Book Description :

Molecular Medicine is the application of genetic or DNA-based knowledge to the modern practice of medicine. Molecular Medicine, 4e, provides contemporary insights into how the genetic revolution is influencing medical thinking and practice. The new edition includes recent changes in personalized medicine, new growth in omics and direct-to-consumer DNA testing, while focusing on advances in the Human Genome project and implications of the advances in clinical medicine. Graduate students, researchers, clinicians and allied health professionals will appreciate the background history and clinical application of up-to-date molecular advances. Extensively revised to incorporate the results of the Human Genome Project, it provides the latest developments in molecular medicine The only book in Molecular Medicine to reach its fourth edition Identifies current practice as well as future developments Presents extensive tables, well presented figures and resources for further understanding

Philosophy of Molecular Medicine

Philosophy of Molecular Medicine Book
Author : Giovanni Boniolo,Marco J. Nathan
Publisher : Taylor & Francis
Release : 2016-11-18
ISBN : 1317378350
Language : En, Es, Fr & De

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Book Description :

Philosophy of Molecular Medicine: Foundational Issues in Theory and Practice aims at a systematic investigation of a number of foundational issues in the field of molecular medicine. The volume is organized around four broad modules focusing, respectively, on the following key aspects: What are the nature, scope, and limits of molecular medicine? How does it provide explanations? How does it represent and model phenomena of interest? How does it infer new knowledge from data and experiments? The essays collected here, authored by prominent scientists and philosophers of science, focus on a handful of mainstream topics in the philosophical literature, such as causation, explanation, modeling, and scientific inference. These previously unpublished contributions shed new light on these traditional topics by integrating them with problems, methods, and results from three prominent areas of contemporary biomedical science: basic research, translational and clinical research, and clinical practice.

Molecular Medicine for Clinicians

Molecular Medicine for Clinicians Book
Author : Barry Mendelow,Michèle Ramsay,Nanthakumarn Chetty,Wendy Stevens,Patrick Arbuthnot,Silke Arndt,Sahle Asfaha,Jacqueline Brown,Alexio Capovilla,Arnold Christianson,Gerrit Coetzee,Theresa Coetzer,Leandra Cronjé,Nigel Crowther,Chrisna Durandt,Adriano Duse,Lindsay Earlam,Debbie Glencross,Nerine Gregersen,Kate Hammond,Tabitha Haw,Nicole Holland,Penny Keene,Hendrik Koornhof,Amanda Krause,Anthony Lane,Zane Lombard,Elizabeth Mayne,Marion Munster,Grant Napier,Andries Oelofse,Lillian Ouko,Maria Papathanasopoulos,Alan Paterson,Michael Pepper,Wolfgang Prinz,Natela Rekhviashvili,Nerina Savage,Barry Schoub,Lesley Scott,Mieneke Smit van Dixhoorn,Himla Soodyall,Gwynneth Stevens,Ahmed Wadee,Sarah Walters,Marco Weinberg,Natalie Whalley,Tracey Wiggill,Pascale Willem
Publisher : Wits University Press
Release : 2008-01-01
ISBN : 1868144658
Language : En, Es, Fr & De

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Book Description :

The insights following the wake of the Human Genome project are radically influencing our understanding of the molecular basis of life, health and disease. The improved accuracy and precision of clinical diagnostics is also beginning to have an impact on therapeutics in a fundamental way. This book is suitable for undergraduate medical students, as part of their basic sciences training, but is also relevant to interested under- and postgraduate science and engineering students. It serves as an introductory text for medical registrars in virtually all specialties, and is also of value to the General Practitioner wishing to keep up to date, especially in view of the growing, internet-assisted public knowledge of the field. There is a special focus on the application of molecular medicine in Africa and in developing countries elsewhere.

Introduction to Molecular Medicine

Introduction to Molecular Medicine Book
Author : Dennis W. Ross
Publisher : Springer Science & Business Media
Release : 2013-03-09
ISBN : 147574076X
Language : En, Es, Fr & De

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Book Description :

How will increased understanding of the human genome affect our ability to diagnose and treat disease? The subject of recombinant DNA technology is no longer limited to the research laboratory; it is being discussed in ever-widening medical circles. Introduction to Molecular Medicine is especially written for the physician who is not a genetics expert but wishes to understand this new science and find entry to the more specialized publications. The first chapters present the basic concepts of the human genome and gene regulation. Subsequent chapters consider how today's new approach can be applied in areas such as forensic medicine, transplantation medicine, drug manufacture and genetic engineering. For example, a major section on cancer explores the diagnosis of leukemia and lymphoma through the detection of gene rearrangement and oncongeny mutation. One feature that will especially interest pathologists, pediatricians and residents is the discussion of diagnostic tests that are used in current practice.

Molecular Medicine

Molecular Medicine Book
Author : Jens Kurreck,Cy Aaron Stein
Publisher : John Wiley & Sons
Release : 2016-02-16
ISBN : 3527331891
Language : En, Es, Fr & De

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Book Description :

Easy to read, yet comprehensive, this is the perfect introduction into the molecular basis of disease and the novel treatment options that have become available. The authors, Jens Kurreck and Cy Stein, have both long-standing teaching experience on the subject, one from a biologist's angle, the other with a medical background. Together, they have produced a modern textbook for courses in Molecular Medicine that incorporates modules from immunology to signaling, from virology to gene therapy, and the latest development in personalized medicine.

Encyclopedia of Molecular Biology and Molecular Medicine Mass Spectrometry High Speed DNA Fragment Sizing to Plasma Lipoproteins

Encyclopedia of Molecular Biology and Molecular Medicine  Mass Spectrometry High Speed DNA Fragment Sizing to Plasma Lipoproteins Book
Author : Robert A. Meyers
Publisher : Wiley-Blackwell
Release : 1996-09-26
ISBN : 9783527284740
Language : En, Es, Fr & De

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Book Description :

This six volume Encyclopedia is the most comprehensive, detailed treatment of molecular biology and molecular medicine available today! The Encyclopedia provides a single-source library of molecular genetics and the molecular basis of life, with a focus on molecular medicine. Genetic screening, gene therapy, structural biology, and the technology and findings of the Human Genome Project are discussed in detail. The articles that comprise the set are designed as self-contained treatments. Each of the nearly 300 articles begins with an outline and a key word section which includes definitions. These features assist the scientist or student who is unfamiliar with a specific subject area. A glossary of basic terms completes each volume and defines the most commonly used terms in molecular biology. Together with the introductory illustrations found in each volume, these definitions enable readers to understand articles without referring to a dictionary, textbook, or other reference.

Molecular Medicine

Molecular Medicine Book
Author : Sinem Nalbantoglu,Hakima Amri
Publisher : BoD – Books on Demand
Release : 2019-11-06
ISBN : 183962759X
Language : En, Es, Fr & De

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Book Description :

Molecular medicine is an applied science focused on human genes/transcripts, proteins, metabolites, and metabolic networks that describes molecular and cellular processes of health and disease onset and progression. Molecular medicine-based integrative identification and characterization of biomarker targets and their clinical translations is essential to explain/decipher the mechanism(s) underlying physiological pathways and pathological conditions, and acquire cell-targeted early interventional and therapeutic strategies in the context of precision medicine and public health. Principally, Molecular Medicine provides an overview of the latest headlines/developments of systems and molecular medicine, highlighting the emerging high-throughput technologies, promising potential applications, and progress in biomedical research and development strategies.

Molecular Medicine

Molecular Medicine Book
Author : R. Trent
Publisher : Academic Press
Release : 2005-04-29
ISBN : 0126990573
Language : En, Es, Fr & De

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Book Description :

Molecular medicine is the application of gene or DNA based knowledge to the modern practice of medicine. This book provides contemporary insights into how the genetic revolution is influencing medical thinking and practice on a broad front including clinical medicine, innovative therapies and forensic medicine. Extensively revised just after the completion of the Human Genome Project, it provides the latest in molecular medicine developments The only book in Molecular Medicine that has undergone three editions Current practice as well as future developments identified Extensive tables, well presented figures - resources for further understanding

Encyclopedia of Molecular Biology and Molecular Medicine Heart Failure Genetic Basis of to Mammalian Genome

Encyclopedia of Molecular Biology and Molecular Medicine  Heart Failure  Genetic Basis of to Mammalian Genome Book
Author : Robert A. Meyers
Publisher : Wiley-Blackwell
Release : 1996
ISBN : 9783527284733
Language : En, Es, Fr & De

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Book Description :

This six volume Encyclopedia is the most comprehensive, detailed treatment of molecular biology and molecular medicine available today! The Encyclopedia provides a single-source library of molecular genetics and the molecular basis of life, with a focus on molecular medicine. Genetic screening, gene therapy, structural biology, and the technology and findings of the Human Genome Project are discussed in detail. The articles that comprise the set are designed as self-contained treatments. Each of the nearly 300 articles begins with an outline and a key word section which includes definitions. These features assist the scientist or student who is unfamiliar with a specific subject area. A glossary of basic terms completes each volume and defines the most commonly used terms in molecular biology. Together with the introductory illustrations found in each volume, these definitions enable readers to understand articles without referring to a dictionary, textbook, or other reference.

Principles of Molecular Cardiology

Principles of Molecular Cardiology Book
Author : Marschall S. Runge,Cam Patterson
Publisher : Springer Science & Business Media
Release : 2007-11-14
ISBN : 1592598781
Language : En, Es, Fr & De

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Book Description :

An easy-to-read survey of all the latest developments in molecular cardiologic research and therapy. The authors explain in a readable style the complex process of the heart's development, the molecular basis of cardiovascular diseases, and the translation of these research advances to actual clinical treatments. The expert information provided here serves as an invaluable building block for novel treatments of cardiovascular diseases and includes a comprehensive discussion of cardiac function and dysfunction, coronary artery disease, cardiac arrhythmias, vascular diseases, and risk factors for cardiovascular disease. These state-of-the-art approaches to molecular cardiologic research include critical discussion of such topics as the molecular events that regulate angiogenesis and the potential for angiogenic therapy, emerging therapies for arrhythmias, and a description of the molecular biology of aging and its impact on the cardiovascular system.

Molecular Medical Parasitology

Molecular Medical Parasitology Book
Author : Joseph Marr,Tim W. Nilsen,Richard W. Komuniecki
Publisher : Elsevier
Release : 2002-12-10
ISBN : 008049191X
Language : En, Es, Fr & De

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Book Description :

A valuable, new source, Molecular Medical Parasitology is the only text of its kind -- one that applies broad concepts and current scientific advances from both molecular biology and biochemistry to the study of parasitic organisms. An internationally renowned team of scientists and physicians places parasites in their broad biological contexts while still emphasizing the specifics that differentiate these organisms. Not only will researchers and faculty in parasitology find this an indispensable guide, physicians will benefit from the thorough coverage molecular biology and biochemistry's current influences on treatment and management of parasitic diseases. Features the most up-to-date scientific methods behind the medical management of parasitic diseases Applies the most current synthesis of molecular biology and biochemistry to parasitic organisms Contains many informative figures and clear illustrations

An Introduction to Molecular Medicine and Gene Therapy

An Introduction to Molecular Medicine and Gene Therapy Book
Author : Thomas F. Kresina
Publisher : John Wiley & Sons
Release : 2004-03-24
ISBN : 0471461040
Language : En, Es, Fr & De

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Book Description :

An Introduction to Molecular Medicine and Gene Therapy Edited by Thomas F. Kresina, Ph.D. Gene therapy, or the use of genetic manipulation for disease treatment, is derived from advances in genetics, molecular biology, clinical medicine, and human genomics. Molecular medicine, the application of molecular biological techniques to disease treatment and diagnosis, is derived from the development of human organ transplantation, pharmacotherapy, and elucidation of the human genome. An Introduction to Molecular Medicine and Gene Therapy provides a basis for interpreting new clinical and basic research findings in the areas of cloning, gene transfer, and targeting; the applications of genetic medicine to clinical conditions; ethics and governmental regulations; and the burgeoning fields of genomics, biotechnology, and bioinformatics. By dividing the material into three sections - an introduction to basic science, a review of clinical applications, and a discussion of the evolving issues related to gene therapy and molecular medicine-this comprehensive manual describes the basic approaches to the broad range of actual and potential genetic-based therapies. In addition, An Introduction to Molecular Medicine and Gene Therapy: * Covers new frontiers in gene therapy, animal models, vectors, gene targeting, and ethical/legal considerations * Provides organ-based reviews of current studies in gene therapy for monogenetic, multifactoral or polygenic disorders, and infectious diseases * Includes bold-faced terms, key concepts, summaries, and lists of helpful references by subject in each chapter * Contains appendices on commercial implications and a review of the history of gene therapy This textbook offers a clear, concise writing style, drawing upon the expertise of the authors, all renowned researchers in their respective specialties of molecular medicine. Researchers in genetics and molecular medicine will all find An Introduction to Molecular Medicine and Gene Therapy to be an essential guide to the rapidly evolving field of gene therapy and its applications in molecular medicine.

Issues in Physiology Cell Biology and Molecular Medicine 2011 Edition

Issues in Physiology  Cell Biology  and Molecular Medicine  2011 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2012-01-09
ISBN : 1464965463
Language : En, Es, Fr & De

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Book Description :

Issues in Physiology, Cell Biology, and Molecular Medicine: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Physiology, Cell Biology, and Molecular Medicine. The editors have built Issues in Physiology, Cell Biology, and Molecular Medicine: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Physiology, Cell Biology, and Molecular Medicine in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Physiology, Cell Biology, and Molecular Medicine: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Molecular Protocols in Transfusion Medicine

Molecular Protocols in Transfusion Medicine Book
Author : Gregory A. Denomme,Maria Rios,Marion E. Reid
Publisher : Elsevier
Release : 2000-04-27
ISBN : 9780080536903
Language : En, Es, Fr & De

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Book Description :

This essential methods manual for immunohematologists (or hematologists and immunohematologists) provides information on genes that encode antigens on red blood cells, platelets and neutrophils. The book begins by covering general concepts in molecular biology and specific protocols such as DNA preparation, PCR-RFLP and allele-specific PCR. Information on the erythrocyte, platelet and neutrophil antigen systems and the molecular basis of polymorphisms are presented clearly in a gene facts sheet format. Database accession numbers and useful adjuncts such as Request forms, worksheets for PCR/enzyme digests also serve to benefit the user. The information is clearly presented and easily accessible and is complemented by the excellent diagrams and tabular material. This book is invaluable for both new and experienced researchers in the field and other related disciplines. Essential for hematologists and those involoved in tissue typing and the study of human genetic polymorphisms Presents clearly and concisely the information on a particular variant and the technique used to detect it Organized by antigen and provides sequences of polymorphisms and primers Details the general concepts and critical information on genes, their products, and sources of relevant nucleic acids Includes protocols that allow investigators to set up assays with minimal effort (protocols include primers, reagents, reaction conditions, sizes of amplified products, restriction fragment digests, and the relevant safety information) Provides information that helps interpret results in clinical settings Contains additional sources of information (e.g., key references, web site addresses, glossary, Database accession numbers, request forms, and worksheets for PCR/enzyme digests)

Techniques in Molecular Medicine

Techniques in Molecular Medicine Book
Author : Friedhelm Hildebrandt,Peter Igarashi
Publisher : Springer Science & Business Media
Release : 2013-11-11
ISBN : 3642598110
Language : En, Es, Fr & De

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Book Description :

This manual not only provides reliable, up-to-date protocols for lab use but also the theoretical background of molecular biology, allowing users to better understand the principles underlying these techniques. It covers a wide range of methods, including the purification of nucleic acids, enzymatic modification of DNA, isolation of specific DNA fragments, PCR, cloning techniques, and gene expression. A Springer Lab Manual

A Contagious Cause

A Contagious Cause Book
Author : Robin Wolfe Scheffler
Publisher : University of Chicago Press
Release : 2019-06-15
ISBN : 022662837X
Language : En, Es, Fr & De

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Book Description :

Is cancer a contagious disease? In the late nineteenth century this idea, and attending efforts to identify a cancer “germ,” inspired fear and ignited controversy. Yet speculation that cancer might be contagious also contained a kernel of hope that the strategies used against infectious diseases, especially vaccination, might be able to subdue this dread disease. Today, nearly one in six cancers are thought to have an infectious cause, but the path to that understanding was twisting and turbulent. ​ A Contagious Cause is the first book to trace the century-long hunt for a human cancer virus in America, an effort whose scale exceeded that of the Human Genome Project. The government’s campaign merged the worlds of molecular biology, public health, and military planning in the name of translating laboratory discoveries into useful medical therapies. However, its expansion into biomedical research sparked fierce conflict. Many biologists dismissed the suggestion that research should be planned and the idea of curing cancer by a vaccine or any other means as unrealistic, if not dangerous. Although the American hunt was ultimately fruitless, this effort nonetheless profoundly shaped our understanding of life at its most fundamental levels. A Contagious Cause links laboratory and legislature as has rarely been done before, creating a new chapter in the histories of science and American politics.

Molecular Imaging

Molecular Imaging Book
Author : Brian D. Ross,Sanjiv S. Gambhir
Publisher : Academic Press
Release : 2021-08-09
ISBN : 0128163879
Language : En, Es, Fr & De

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Book Description :

The detection and measurement of the dynamic regulation and interactions of cells and proteins within the living cell are critical to the understanding of cellular biology and pathophysiology. The multidisciplinary field of molecular imaging of living subjects continues to expand with dramatic advances in chemistry, molecular biology, therapeutics, engineering, medical physics and biomedical applications. Molecular Imaging: Principles and Practice, Volumes 1 and 2, Second Edition provides the first point of entry for physicians, scientists, and practitioners. This authoritative reference book provides a comprehensible overview along with in-depth presentation of molecular imaging concepts, technologies and applications making it the foremost source for both established and new investigators, collaborators, students and anyone interested in this exciting and important field. The most authoritative and comprehensive resource available in the molecular-imaging field, written by over 170 of the leading scientists from around the world who have evaluated and summarized the most important methods, principles, technologies and data Concepts illustrated with over 600 color figures and molecular-imaging examples Chapters/topics include, artificial intelligence and machine learning, use of online social media, virtual and augmented reality, optogenetics, FDA regulatory process of imaging agents and devices, emerging instrumentation, MR elastography, MR fingerprinting, operational radiation safety, multiscale imaging and uses in drug development This edition is packed with innovative science, including theranostics, light sheet fluorescence microscopy, (LSFM), mass spectrometry imaging, combining in vitro and in vivo diagnostics, Raman imaging, along with molecular and functional imaging applications Valuable applications of molecular imaging in pediatrics, oncology, autoimmune, cardiovascular and CNS diseases are also presented This resource helps integrate diverse multidisciplinary concepts associated with molecular imaging to provide readers with an improved understanding of current and future applications

Molecular Medicine

Molecular Medicine Book
Author : R. J. Trent
Publisher : Unknown
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The second edition of this popular book provides an overview of the impact which recombinant DNA (rDNA) technology is having on medical practice. Called molecular medicine, this rapidly expanding area has an increasing role to play in medicine and this book addresses the importance of this challenging area. This new edition has been fully updated with the developments of the last few years. Key genes identified include BRCA1 (breast cancer) OB (obese) and those involved in DNA repair. In addition the author covers the increase in gene therapy trials and the shifting of emphasis from genetic disorders to the cancers and HIV infection. Places molecular advances in a clinical setting, making it relevant to medical students Does not include any unnecessary detail and avoids using specialist jargon Covers a very topical and increasingly vital subject as molecular techniques now impinge on every branch of medicine Is the only source of easily understandable basic information in this field Fully updated throughout with the latest developments including information on the recently identified genes BRCA1 (breast cancer) OB (obese) and those involved in DNA repair Covers the increase in gene therapy trials and the shifting of emphasis from genetic disorders to the cancers and HIV infection First edition won the 1994 BUPA prize for best medical textbook

Genome Chaos

Genome Chaos Book
Author : Henry H. Heng
Publisher : Academic Press
Release : 2019-05-25
ISBN : 0128136367
Language : En, Es, Fr & De

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Book Description :

Genome Chaos: Rethinking Genetics, Evolution, and Molecular Medicine transports readers from Mendelian Genetics to 4D-genomics, building a case for genes and genomes as distinct biological entities, and positing that the genome, rather than individual genes, defines system inheritance and represents a clear unit of selection for macro-evolution. In authoring this thought-provoking text, Dr. Heng invigorates fresh discussions in genome theory and helps readers reevaluate their current understanding of human genetics, evolution, and new pathways for advancing molecular and precision medicine. Bridges basic research and clinical application and provides a foundation for re-examining the results of large-scale omics studies and advancing molecular medicine Gathers the most pressing questions in genomic and cytogenomic research Offers alternative explanations to timely puzzles in the field Contains eight evidence-based chapters that discuss 4d-genomics, genes and genomes as distinct biological entities, genome chaos and macro-cellular evolution, evolutionary cytogenetics and cancer, chromosomal coding and fuzzy inheritance, and more