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Molecular Imaging

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Molecular Imaging

Molecular Imaging Book
Author : Ralph Weissleder
Publisher : PMPH-USA
Release : 2010
ISBN : 9781607950059
Language : En, Es, Fr & De

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Book Description :

The field of molecular imaging of living subjects have evolved considerably and have seen spectacular advances in chemistry, engineering and biomedical applications. This textbook was designed to fill the need for an authoritative source for this multi-disciplinary field. We have been fortunate to recruit over 80 leading authors contributing 75 individual chapters. Given the multidisciplinary nature of the field, the book is broken into six different sections: "Molecular Imaging technologies", "Chemistry", "Molecular Imaging in Cell and Molecular Biology", "Applications of Molecular Imaging", "Molecular Imaging in Drug Evaluation" with the final section comprised of chapters on computation, bioinformatics and modeling. The organization of this large amount of information is logical and strives to avoid redundancies among chapters. It encourages the use of figures to illustrate concepts and to provide numerous molecular imaging examples.

Molecular Imaging

Molecular Imaging Book
Author : Jie Tian
Publisher : Springer Science & Business Media
Release : 2013-07-23
ISBN : 3642343031
Language : En, Es, Fr & De

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Book Description :

"Molecular Imaging: Fundamentals and Applications" is a comprehensive monograph which describes not only the theory of the underlying algorithms and key technologies but also introduces a prototype system and its applications, bringing together theory, technology and applications. By explaining the basic concepts and principles of molecular imaging, imaging techniques, as well as research and applications in detail, the book provides both detailed theoretical background information and technical methods for researchers working in medical imaging and the life sciences. Clinical doctors and graduate students will also benefit from this book. Jie Tian is a professor at the Institute of Automation, Chinese Academy of Sciences, China.

Molecular Imaging I

Molecular Imaging I Book
Author : Wolfhard Semmler,Markus Schwaiger
Publisher : Springer
Release : 2010-11-30
ISBN : 9783642091827
Language : En, Es, Fr & De

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Book Description :

The aim of this textbook of molecular imaging is to provide an up to date review of this rapidly growing field and to discuss basic methodological aspects necessary for the interpretation of experimental and clinical results. Emphasis is placed on the interplay of imaging technology and probe development, since the physical properties of the imaging approach need to be closely linked with the biologic application of the probe (i.e. nanoparticles and microbubbles). Various chemical strategies are discussed and related to the biologic applications. Reporter-gene imaging is being addressed not only in experimental protocols, but also first clinical applications are discussed. Finally, strategies of imaging to characterize apoptosis and angiogenesis are described and discussed in the context of possible clinical translation.

Molecular Imaging in Oncology

Molecular Imaging in Oncology Book
Author : Otmar Schober,Burkhard Riemann
Publisher : Springer Science & Business Media
Release : 2012-11-28
ISBN : 3642108539
Language : En, Es, Fr & De

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Book Description :

The impact of molecular imaging on diagnostics, therapy, and follow-up in oncology is increasing steadily. Many innovative molecular imaging probes have already entered clinical practice, and there is no doubt that the future emphasis will be on multimodality imaging in which morphological, functional, and molecular imaging techniques are combined in a single clinical investigation. This handbook addresses all aspects of molecular imaging in oncology, from basic research to clinical applications. The first section is devoted to technology and probe design, and examines a variety of PET and SPECT tracers as well as multimodality probes. Preclinical studies are then discussed in detail, with particular attention to multimodality imaging. In the third section, diverse clinical applications are presented, and the book closes by looking at future challenges. This handbook will be of value to all who are interested in the revolution in diagnostic oncology that is being brought about by molecular imaging.

Molecular Imaging of the Brain

Molecular Imaging of the Brain Book
Author : M. M. Kaila,Rakhi Kaila
Publisher : Springer Science & Business Media
Release : 2012-09-20
ISBN : 3642303013
Language : En, Es, Fr & De

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Book Description :

This book examines multi-quantum magnetic resonance imaging methods and the diagnostics of brain disorders. It consists of two Parts. The part I is initially devoted towards the basic concepts of the conventional single quantum MRI techniques. It is supplemented by the basic knowledge required to understand multi-quantum MRI. Practical illustrations are included both on recent developments in conventional MRI and the MQ-MRI. This is to illustrate the connection between theoretical concepts and their scope in the clinical applications. The Part II initially sets out the basic details about quadrupole charge distribution present in certain nuclei and their importance about the functions they perform in our brain. Some simplified final mathematical expressions are included to illustrate facts about the basic concepts of the quantum level interactions between magnetic dipole and the electric quadrupole behavior of useful nuclei present in the brain. Selected practical illustrations, from research and clinical practices are included to illustrate the newly emerging ideas and techniques. The reader should note that the two parts of the book are written with no interdependence. One can read them quite independently.

Molecular Imaging

Molecular Imaging Book
Author : Hossein Jadvar,Michael Graham,Heather Jacene
Publisher : Cambridge University Press
Release : 2017-10-31
ISBN : 1107621283
Language : En, Es, Fr & De

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Book Description :

Trace the history, and advances in the field of molecular imaging, with this guide to the visual world of disease.

Fluorine and Health

Fluorine and Health Book
Author : Alain Tressaud,Gunter Haufe
Publisher : Elsevier
Release : 2008-06-06
ISBN : 9780080558110
Language : En, Es, Fr & De

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Book Description :

Fluorine and Health presents a critical multidisciplinary overview on the contribution of fluorinated compounds to resolve the important global issue of medicinal monitoring and health care. The involved subjects are organized in three thematic parts devoted to Molecular Imaging, Biomedical Materials and Pharmaceuticals. Initially the key-position of partially fluorinated low molecular weight compounds labelled either with the natural 19F-isotope for Magnetic Resonance Imaging (MRI) or labelled with the radioactive [18F]-isotope for Positron Emission Tomography (PET) is highlighted. Both non-invasive methods belong to the most challenging in vivo imaging techniques in oncology, neurology and in cardiology for the diagnosis of diseases having the highest mortality in the industrialized countries. The manifold facets of fluorinated biomaterials range from inorganic ceramics to perfluorinated organic molecules. Liquid perfluorocarbons are suitable for oxygen transport and as potential respiratory gas carriers, while fluorinated polymers are connected to the pathology of blood vessels. Another important issue concerns the application of highly fluorinated liquids in ophthalmology. Moreover, fluorine is an essential trace element in bone mineral, dentine and tooth enamel and is applied for the prophylaxis and treatment of dental caries. The various origins of human exposure to fluoride species is detailed to promote a better understanding of the effect of fluoride species on living organisms. Medicinally relevant fluorinated molecules and their interactions with native proteins are the main focus of the third part. New molecules fluorinated in strategic position are crucial for the development of pharmaceuticals with desired action and optimal pharmacological profile. Among the hundreds of marketed active drug components there are more than 150 fluorinated compounds. The chapters will illustrate how the presence of fluorine atoms alters properties of bioactive compounds at various biochemical steps, and possibly facilitate its emergence as pharmaceuticals. Finally the synthetic potential of a fluorinase, the first C-F bond forming enzyme, is summarized. - New approach of topics involving chemistry, biology and medicinal techniques - Transdisciplinar papers on fluoride products - Importance of fluoride products in health - Updated data on specific topics

Pediatric Nuclear Medicine and Molecular Imaging

Pediatric Nuclear Medicine and Molecular Imaging Book
Author : S.Ted. Treves
Publisher : Springer
Release : 2014-05-16
ISBN : 1461495512
Language : En, Es, Fr & De

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Book Description :

This pioneering book, now in its fourth edition, presents the cutting-edge developments in pediatric nuclear medicine. Thoroughly revised and updated, it retains the fundamentals that anchor the book’s distinguished reputation and includes the latest advances in PET/CT, SPECT, hybrid imaging, and molecular imaging. Pediatric Nuclear Medicine and Molecular Imaging, Fourth Edition, is an excellent resource for nuclear medicine physicians, diagnostic radiologists, pediatricians, and residents and fellows. The Fourth Edition features: · 16 new chapters, including PET and PET/CT in Children and Young Adults; Lymphoscintigraphy; Skeletal Scintigraphy; Neuroblastoma; Lymphomas and Lymphoproliferative Disorders; Functional Imaging of Pediatric Musculoskeletal Tumors; Solid Tumors in Childhood; Pediatric Molecular Imaging; Combined PET/MRI in Childhood; Radiation Exposures; Radiation Protection in Pediatric Nuclear Medicine; and Dose Optimization in Pediatric Nuclear Medicine. · Discussion of the use of image fusion and hybrid imaging in children. · Strategies for communicating potential radiation risk to patients, families and members of the healthcare team. · Methods to optimize pediatric radiopharmaceutical administered doses and improve image quality. S. Ted Treves, MD, is Professor of Radiology at Harvard Medical School, Founder and Former Chief, Division of Nuclear Medicine and Molecular Imaging, Ch ildren’s Hospital Boston (1970-2011). In 2013, he received the Society of Nuclear Medicine and Molecular Imaging’s Georg Charles de Hevesy Nuclear Pioneer Award for outstanding contributions to the field of Nuclear Medicine.

Essentials of Nuclear Medicine and Molecular Imaging E Book

Essentials of Nuclear Medicine and Molecular Imaging E Book Book
Author : Fred A. Mettler,Milton J. Guiberteau
Publisher : Elsevier Health Sciences
Release : 2018-08-17
ISBN : 0323567894
Language : En, Es, Fr & De

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Book Description :

Covering both the fundamentals and recent developments in this fast-changing field, Essentials of Nuclear Medicine and Molecular Imaging, 7th Edition, is a must-have resource for radiology residents, nuclear medicine residents and fellows, nuclear medicine specialists, and nuclear medicine technicians. Known for its clear and easily understood writing style, superb illustrations, and self-assessment features, this updated classic is an ideal reference for all diagnostic imaging and therapeutic patient care related to nuclear medicine, as well as an excellent review tool for certification or MOC preparation. Provides comprehensive, clear explanations of everything from principles of human physiology, pathology, physics, radioactivity, radiopharmaceuticals, radiation safety, and legal requirements to hot topics such as new brain and neuroendocrine tumor agents and hybrid imaging, including PET/MR and PET/CT. Covers the imaging of every body system, as well as inflammation, infection and tumor imaging; pearls and pitfalls for every chapter; and pediatric doses and guidelines in compliance with the Image Gently and Image Wisely programs. Features a separate self-assessment section on differential diagnoses, imaging procedures and artifacts, and safety issues with unknown cases, questions, answers, and explanations. Includes new images and illustrations, for a total of 430 high-quality, multi-modality examples throughout the text. Reflects recent advances in the field, including updated nuclear medicine imaging and therapy guidelines • Updated dosimetry values and effective doses for all radiopharmaceuticals with new values from the 2015 International Commission on Radiological Protection • Updated information regarding advances in brain imaging, including amyloid, dopamine transporter and dementia imaging • Inclusion of Ga-68 DOTA PET/CT for neuroendocrine tumors • Expanded information on correlative and hybrid imaging with SPECT/CT • New myocardial agents • and more. Contains extensive appendices including updated comprehensive imaging protocols for routine and hybrid imaging, pregnancy and breastfeeding guidelines, pediatric dosages, non-radioactive pharmaceuticals used in interventional and cardiac stress imaging, and radioactivity conversion tables.

Molecular Imaging Basic Principles And Applications In Biomedical Research 3rd Edition

Molecular Imaging  Basic Principles And Applications In Biomedical Research  3rd Edition  Book
Author : Markus Rudin
Publisher : World Scientific
Release : 2020-04-04
ISBN : 1786346869
Language : En, Es, Fr & De

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Book Description :

The area of molecular imaging has matured over the past decade and is still growing rapidly. Many concepts developed for molecular biology and cellular imaging have been successfully translated to in vivo imaging of intact organisms. Molecular imaging enables the study of processes at a molecular level in their full biological context. Due to the high specificity of the molecular readouts the approach bears a high potential for diagnostics. It is fair to say that molecular imaging has become an indispensable tool for biomedical research and drug discovery and development today.This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities, and the design of targeted probes are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events in the living organism. Topics covered include the studies of the biodistribution of reporter probes and drugs, visualization of the expression of biomolecules such as receptors and enzymes, and how imaging can be used for analyzing consequences of the interaction of a ligand or a drug with its molecular target by visualizing signal transduction, or assessing the metabolic, physiological, or structural response of the organism studied.The third edition has been extended considerably. This holds for the chapter on imaging modalities, which now includes sections on intravital microscopy and mass spectrometric imaging. All chapters have been updated and a new chapter on the challenges of translating molecular imaging solutions for clinical use has been added.

Molecular Imaging Probes for Cancer Research

Molecular Imaging Probes for Cancer Research Book
Author : Xiaoyuan Chen
Publisher : World Scientific
Release : 2012
ISBN : 9814293679
Language : En, Es, Fr & De

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Book Description :

This review volume integrates the advances in cancer biology, molecular imaging techniques and imaging probes for visualization and quantitative measurement of anatomical, functional, and molecular profiles of cancer. The volume also presents a comprehensive summary of the state-of-the-art technology in molecular imaging probe design and applications in radionuclide (PET and SPECT), magnetic resonance (MR), optical (fluorescence, Raman, photoacoustic), ultrasound, CT, and multimodality imaging. Bringing together the fundamentals of molecular imaging, and the basic principles of each molecular imaging modality in this volume, readers' understanding in this field is further enhanced. With a strong emphasis on the chemistry of the design of appropriate molecular imaging probes for early cancer detection, therapy-response monitoring, and anti-cancer drug development, the process of translating novel cancer imaging probes from bench to bedside is extensively discussed.

Ultrasonic molecular imaging with targeted microbubbles

Ultrasonic molecular imaging with targeted microbubbles Book
Author : Shukui Zhao
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Ultrasonic molecular imaging with targeted microbubbles book written by Shukui Zhao, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

PET

PET Book
Author : Michael E. Phelps
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 0387225293
Language : En, Es, Fr & De

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Book Description :

This book is written as both a text and a reference book. It contains numerous images from the biological sciences and clinical practice, tables, graphs, and fig ures, as well as exercises that are worked out to aid the reader in understanding principles or solving problems. In some cases, derivations are placed in appen dices so as not to break up the flow of the subject matter in the text. The book is intended for a broad audience interested in molecular imaging with positron emission tomography (PET). It is expected that the readers will range from undergraduate, graduate, and medical students to residents, physi cians, and scientists with backgrounds from various physical, biological, and medical specialty areas. Each chapter presents material in a straightforward man ner that is well illustrated and explained. Because of the diverse audience for the book, certain chapters or sections of chapters will be of more interest than oth ers to certain segments of the readership. Chapter 1 introduces the fundamental physics upon which PET imaging sys tems is based and discusses in detail the technologies and methods used to pro duce PET images. The chapter starts out by reviewing the physics of positron emission and annihilation and explains how positron range and photon non colinearity in coincidence detection place certain limits on spatial resolution.

Nuclear Medicine and Molecular Imaging the Requisites

Nuclear Medicine and Molecular Imaging  the Requisites Book
Author : Janis P. O'Malley,Harvey A. Ziessman
Publisher : Elsevier
Release : 2019-11
ISBN : 9780323530378
Language : En, Es, Fr & De

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Book Description :

Now in its 5th Edition, this outstanding volume in the popular Requisites series thoroughly covers the fast-changing field of nuclear medicine and molecular imaging. Ideal for residency, clinical rotations, and board review, this compact and authoritative volume by Drs. Janis O'Malley and Harvey Ziessman covers the conceptual, factual, and interpretive information you need to know for success on exams and in clinical practice. NEW to this edition: More content on molecular imaging and the latest advances in clinical applications, including positron emission tomography (PET), SPECT/CT, PET/CT, and PET/MRI hybrid imaging. Inclusion of newly approved tracers such as Ga68 DOTA, F-18 amyloid, and F-18 PSMA. Expanded and integrated content on physics and non-interpretive aspects, including regulatory issues, radiation safety, and quality control. Up-to-date applications of nuclear medicine in the endocrine, skeletal, hepatobiliary, genitourinary, pulmonary, gastrointestinal, central nervous, and cardiac systems, as well as PET applications for oncology. In the outstanding Requisites tradition, the 5th Edition also: Summarizes key information with numerous outlines, tables, pearls, pitfalls, and frequently asked questions. Focuses on essentials to pass the certifying board exam and ensure accurate diagnoses in clinical practice. Helps you clearly visualize the findings you're likely to see in practice and on exams with nearly 200 full-color images. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all the text, figures, and references from the book on a variety of electronic devices.

Molecular Imaging Basic Principles And Applications In Biomedical Research 2nd Edition

Molecular Imaging  Basic Principles And Applications In Biomedical Research  2nd Edition  Book
Author : Rudin Markus
Publisher : World Scientific
Release : 2013-07-04
ISBN : 1783263172
Language : En, Es, Fr & De

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Book Description :

The area of molecular imaging has matured over the past decade and is still growing rapidly. Many concepts developed for molecular biology and cellular imaging have been successfully translated to in vivo imaging of intact organisms. Molecular imaging enables the study of processes at a molecular level in their full biological context. Due to the high specificity of the molecular readouts the approach bears a high potential for diagnostics. It is fair to say that molecular imaging has become an indispensable tool for biomedical research and drug discovery and development today.This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities, and the design of targeted probes are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events in the living organism. Topics covered include the studies of the biodistribution of reporter probes and drugs, visualization of the expression of biomolecules such as receptors and enzymes, and how imaging can be used for analyzing consequences of the interaction of a ligand or a drug with its molecular target by visualizing signal transduction, or assessing the metabolic, physiological, or structural response of the organism studied. The final chapter deals with visualization of cell migration, for example in the context of cell therapies.The second edition covers novel developments over recent years, in particular regarding imaging technologies (hybrid techniques) and novel reporter concepts. Novel biomedical applications have been included, where appropriate. All the chapters have been thoroughly reworked and the artwork updated.

In Vivo Molecular Imaging Probes for Alzheimer s Disease

In Vivo Molecular Imaging Probes for Alzheimer s Disease Book
Author : Eric Dustin Agdeppa
Publisher : Ann Arbor, Mich. : University Microfilms International
Release : 2002
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download In Vivo Molecular Imaging Probes for Alzheimer s Disease book written by Eric Dustin Agdeppa, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Nanoplatform Based Molecular Imaging

Nanoplatform Based Molecular Imaging Book
Author : Xiaoyuan Chen
Publisher : John Wiley & Sons
Release : 2011-04-20
ISBN : 1118110021
Language : En, Es, Fr & De

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Book Description :

The cutting-edge guide on advancing the science of molecular imaging using nanoparticles Nanoplathform-Based Molecular Imaging provides rationale for using nanoparticle-based probes for molecular imaging, then discusses general strategies for this underutilized, yet promising, technology. It addresses general strategies of particle synthesis and surface chemistry, applications in computed tomography optical imaging, magnetic resonance imaging, ultrasound, multimodality imaging, theranostics, and finally, the clinical perspectives of nanoimaging. This comprehensive volume summarizes the opinions of those in the forefront of research and describes the latest developments by emphasizing fundamentals and initiating hands-on application.

Molecular Imaging Biomarkers in the Evaluation of Experimental Therapeutics

Molecular Imaging Biomarkers in the Evaluation of Experimental Therapeutics Book
Author : Kuei Chung Lee
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Molecular Imaging Biomarkers in the Evaluation of Experimental Therapeutics book written by Kuei Chung Lee, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Molecular Imaging in Parkinson s Disease

Molecular Imaging in Parkinson s Disease Book
Author : Cristina Polito
Publisher : Firenze University Press
Release : 2011
ISBN : 886655037X
Language : En, Es, Fr & De

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Book Description :

Download Molecular Imaging in Parkinson s Disease book written by Cristina Polito, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Molecular Imaging with Reporter Genes

Molecular Imaging with Reporter Genes Book
Author : Sanjiv Sam Gambhir,Shahriar S. Yaghoubi
Publisher : Cambridge University Press
Release : 2010-05-31
ISBN : 1139489526
Language : En, Es, Fr & De

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Book Description :

Reporter genes have been used for several decades to study regulation of gene expression in vivo. However, it was little more than a decade ago that a new class of reporter genes was developed for imaging molecular events within living subjects. By following the interactions of protein molecules, researchers can resolve the complex chemical pathways that living cells utilise. This book focuses on this group of imaging reporter genes, starting with detailed descriptions of all reporter genes from different imaging modalities, including optical, MRI, and radionuclide-based imaging. Key scientists in the field explain how to enhance reporter gene imaging utility through instrumentation and the various applications of this technology. This is the first comprehensive book on all aspects of reporter gene imaging, detailing what is known in the field and future goals for research. Investigators in biomedical sciences, physicians, and the biotechnology and pharmaceutical industries will benefit from topics covered.