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Molecular Genetic And Statistical Techniques For Behavioral And Neural Research

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Molecular Genetic and Statistical Techniques for Behavioral and Neural Research

Molecular Genetic and Statistical Techniques for Behavioral and Neural Research Book
Author : Robert T. Gerlai
Publisher : Academic Press
Release : 2018-04-24
ISBN : 0128041161
Language : En, Es, Fr & De

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Book Description :

Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior, a critical piece of the puzzle for clinicians, scientists, course instructors and advanced undergraduate and graduate students. Chapters examine neuroinformatics, genetic and neurobehavioral databases and data mining, also providing an analysis of natural genetic variation and principles and applications of forward (mutagenesis) and reverse genetics (gene targeting). In addition, the book discusses gene expression and its role in brain function and behavior, along with ethical issues in the use of animals in genetics testing. Written and edited by leading international experts, this book provides a clear presentation of the frontiers of basic research as well as translationally relevant techniques that are used by neurobehavioral geneticists. Focuses on new techniques, including electrocorticography, functional mapping, stereo EEG, motor evoked potentials, optical coherence tomography, magnetoencephalography, laser evoked potentials, transmagnetic stimulation, and motor evoked potentials Presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior Written and edited by leading international experts

Neurobehavioral Genetics

Neurobehavioral Genetics Book
Author : Byron C. Jones,Pierre Mormede
Publisher : CRC Press
Release : 2006-08-30
ISBN : 9781420003567
Language : En, Es, Fr & De

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Book Description :

A complete background to concepts and principles of behavioral genetics, Neurobehavioral Genetics: Methods and Applications, Second Edition features a broad spectrum of the most current techniques in neurobehavioral genetics in a single source. International researchers incorporate several new developments in the field, including: De

Methods in Genomic Neuroscience

Methods in Genomic Neuroscience Book
Author : Hemin R. Chin,Steven O. Moldin
Publisher : CRC Press
Release : 2001-09-26
ISBN : 1420038478
Language : En, Es, Fr & De

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Book Description :

The past few years have witnessed extraordinary advances in molecular genetic techniques and the accumulation of structural genomics information and resources in both human and model organisms. With the development of new technologies and the availability of resources like the sequence of eukaryotic genomes, problems of a previously unthinkable sco

Handbook of Molecular Genetic Techniques for Brain and Behavior Research

Handbook of Molecular Genetic Techniques for Brain and Behavior Research Book
Author : Wim E. Crusio,R.T. Gerlai
Publisher : Elsevier
Release : 1999-10-18
ISBN : 9780080536866
Language : En, Es, Fr & De

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Book Description :

The book gives a broad overview of recombinant DNA techniques for the behavioral neuroscientist, with illustrative examples of applications. Species covered include rodents (mainly mice), Drosophila melanogaster, Caenorhabditis elegans and Danio rerio. Experimental techniques required to characterize the behavioral phenotypes of mutant animals is provided. Several aspects of novel molecular-genetic techniques are overviewed and possible research strategies are explained. The sections of the book start with general descriptions of techniques followed by illustrative examples. It is divided into six sections. Section 1, bioinformatics and genomics research. Section 2, top-down strategies, where the researcher starts with the phenotype and then analyzes the associated genes; bottom-up strategies, where the physiological chain leading to a phenotype is analyzed starting from the gene product. Section 3, transgenic approaches in rodents including overexpressing foreign genes and gene-targeting; systemic manipulation approaches directly targeting the central nervous system and methods used with invertebrates. Section 4, methods used to evaluate relevant behavioral phenotypes, including learning and aggression. Section 5, examples on molecular brain research in man. Section 6, ethical aspects of research in this field.

Handbook of Child Psychology Theoretical Models of Human Development

Handbook of Child Psychology  Theoretical Models of Human Development Book
Author : William Damon,Richard M. Lerner
Publisher : John Wiley & Sons
Release : 2006-05-19
ISBN : 0471756040
Language : En, Es, Fr & De

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Book Description :

Part of the authoritative four-volume reference that spans the entire field of child development and has set the standard against which all other scholarly references are compared. Updated and revised to reflect the new developments in the field, the Handbook of Child Psychology, Sixth Edition contains new chapters on such topics as spirituality, social understanding, and non-verbal communication. Volume 1: Theoretical Models of Human Development, edited by Richard M. Lerner, Tufts University, explores a variety of theoretical approaches, including life-span/life-course theories, socio-culture theories, structural theories, object-relations theories, and diversity and development theories. New chapters cover phenomenology and ecological systems theory, positive youth development, and religious and spiritual development.

Behavior Genetics of Cognition Across the Lifespan

Behavior Genetics of Cognition Across the Lifespan Book
Author : Deborah Finkel,Chandra A. Reynolds
Publisher : Springer Science & Business Media
Release : 2013-07-09
ISBN : 1461474477
Language : En, Es, Fr & De

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Book Description :

Along with psychopathology, cognition has been one of the primary phenotypic focal points of the field of behavior genetics since its inception. Francis Galton’s 1874 examination of eminent families in Britain was among the earliest attempts to investigate whether cognitive achievements run in families. This volume presents current methodologies for understanding cognitive abilities that move beyond the outdated nature vs. nurture paradigm. Recent advances in both collection and statistical modeling of twin data, particularly longitudinal twin data, make this an especially advantageous moment to produce a work that presents a collection of the groundbreaking research on cognitive abilities across the lifespan. This volume presents an overview of the current state of quantitative and molecular genetic investigations into the many facets of cognitive performance and functioning across the lifespan.​

Handbook of Molecular and Cellular Methods in Biology and Medicine

Handbook of Molecular and Cellular Methods in Biology and Medicine Book
Author : Leland J. Cseke,Ara Kirakosyan,Peter B. Kaufman,Margaret V. Westfall
Publisher : CRC Press
Release : 2016-04-19
ISBN : 1439881952
Language : En, Es, Fr & De

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Book Description :

Several milestones in biology have been achieved since the first publication of the Handbook of Molecular and Cellular Methods in Biology and Medicine. This is true particularly with respect to genome-level sequencing of higher eukaryotes, the invention of DNA microarray technology, advances in bioinformatics, and the development of RNAi technology

Directory of Research Grants 2002

Directory of Research Grants 2002 Book
Author : Grants Program,Oryx Publishing
Publisher : Greenwood
Release : 2002
ISBN : 9781573564885
Language : En, Es, Fr & De

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Book Description :

More than 5,100 current programs from 1,880 sponsors, including U.S. and foreign foundations, corporations, government agencies, and other organizations.

What s Wrong With My Mouse

What s Wrong With My Mouse  Book
Author : Jacqueline N. Crawley
Publisher : John Wiley & Sons
Release : 2007-05-11
ISBN : 0470119047
Language : En, Es, Fr & De

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Book Description :

Dr. Jacqueline N. Crawley, author of the First and Second Editions of What’s Wrong with My Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice,continues to field calls and e-mails from molecular geneticists who ask: how do I run behavioral assays to find out what’s wrong with my mouse? Turn to What’s Wrong with My Mouse? to discover the wealth of mouse behavioral tasks and to get the guidance you need to select the best methods and necessary controls. Chapters are organized by behavioral domain, including measurements of general health, motor functions, sensory abilities, learning and memory, feeding and drinking, reproductive, social, emotional, and reward behaviors in mutant mice. Throughout the chapters, new behavioral tasks and new research discoveries have been added, bringing the Second Edition up to date with the latest science. In addition, the Second Edition includes two new chapters: "Neurodevelopment and Neurodegeneration" discusses mouse behavioral tasks relevant to neurodevelopmental diseases, such as mental retardation and autism, and to neurodegenerative diseases, such as Alzheimers, Parkinsons, Huntingtons, and amyotrophic lateral sclerosis. "Putting It All Together" recommends strategies for optimizing a battery of behavioral phenotyping tests to address your specific hypotheses about gene functions. The final chapter, "The Next Generation," examines new and emerging technologies. Throughout the book, the use of behavioral testing equipment is illustrated with photographs, diagrams, and representative data. Examples of behavioral tasks successfully applied to transgenic and knockout mouse models are provided, as well as references to the primary literature and step-by-step methods protocols. These features, along with a comprehensive index, listings of database and vendor websites, and an extensive list of references, make this book a valuable and practical resource for students and researchers.

Neurosciences at the Postgenomic Era

Neurosciences at the Postgenomic Era Book
Author : Jacques Mallet,Yves Christen
Publisher : Springer Science & Business Media
Release : 2003-04-08
ISBN : 9783540001942
Language : En, Es, Fr & De

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Book Description :

In this new volume in the series Research and Perspectives in Neurosciences the authors have presented and discussed their findings in the fields of speech and language disorders, X-linked mental retardation, gene therapy in the CNS, memory and learning disorders and other fields.

Genetic Influences on Neural and Behavioral Functions

Genetic Influences on Neural and Behavioral Functions Book
Author : Donald W. Pfaff,Wade H. Berrettini,Tong H. Joh,Stephen C. Maxson
Publisher : CRC Press
Release : 1999-07-27
ISBN : 9781420048223
Language : En, Es, Fr & De

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Book Description :

Utilizing the flood of information derived from the Human Genome Project and corresponding efforts to elucidate the mouse genome, Genetic Influences on Neural and Behavioral Functions provides a scholarly catalog, organized logically, of relations between the expression of specific genes, nerve cell biology and behavior, normal and abnormal, in animals AND humans. Sample topics include genes in relation to schiziphrenia, panic disorder, epilepsy, alcoholism, sleep, eating disorders, and more.

Personality 101

Personality 101 Book
Author : Tomas Chamorro-Premuzic, PhD,Gorkan Ahmetoglu, PhD
Publisher : Springer Publishing Company
Release : 2012-09-10
ISBN : 0826107850
Language : En, Es, Fr & De

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Book Description :

“Personality psychology concerns what most people think psychology should be about. This book is the best introduction to personality psychology available anywhere. It combines clear, accessible, and engaging writing with a thorough grasp of the key research and methodological issues in the field. Readers at almost any level of sophistication will find the book enjoyable and informative.” Robert Hogan, Ph.D. President, Hogan Assessment Systems "Broad, authoritative, and above all, clear, this lively book is the ideal introduction to the vibrant field of personality. By blending solid coverage of established theories and findings with discussion of the latest developments and controversies, Personality 101 will be the go-to book for anyone wanting firm foundation in the field." Sam Gosling, Ph.D. Professor of Psychology, University of Texas, Austin Author of Snoop: What your stuff says about you “This is a seriously good book. It is written in a very approachable style by two world experts who really know the literature. I has an ‘un-put-downable’ quality, like a great novel, that students everywhere will really appreciate.” Adrian Furnham, D.Phil (Oxford) D.Sc (London) Professor of Psychology, University College London What is personality? How do we measure personality? Does nature or nurture play a bigger role in our destiny? Is it possible to change our personality for the better? This unique text presents the most current scientific findings about personality in a friendly, jargon-free format. Distilling the vast research on this fascinating topic, the book addresses various historical views of personality and compares and contrasts the reigning “Five Factor” Model with the most current competing models of personality. The authors discuss techniques of assessing personality and provide essential information on its role in life outcomes ranging from career choice to happiness and interpersonal relationships. The text also addresses controversies and moral implications pertaining to the application of personality assessment in social, organizational, and business contexts. It offers a comprehensive account of the consequences of personality on people’s lives, including such areas as religious and political attitudes and implications for health. With its concise format, clarification of complex research methodologies, and comprehensive coverage of widely established as well as controversial information about personality, this book will appeal to a wide range of audiences, including students in psychology and business disciplines. Key Features: Evaluates the “Five Factor” Model of personality--the most widely established personality classification system in psychology Addresses controversies surrounding the application of personality assessment in social, organizational, and business contexts Reviews evidence demonstrating the ability of personality traits to predict “real life” outcomes such as career success and romantic relationships Covers a wide range of theories, methodologies, and findings in a jargon-free, concise format

Developmental Psychopathology Developmental Neuroscience

Developmental Psychopathology  Developmental Neuroscience Book
Author : Donald J. Cohen
Publisher : John Wiley & Sons
Release : 2006-02-17
ISBN : 0470048190
Language : En, Es, Fr & De

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Book Description :

This volume applies multiple levels of analysis to neurobiological developmental organization, and functioning in normality and psychopathology. It also covers topics central to a developmental perspective on neuroscience.

Research Methods in Psycholinguistics and the Neurobiology of Language

Research Methods in Psycholinguistics and the Neurobiology of Language Book
Author : Annette M. B. de Groot,Peter Hagoort
Publisher : John Wiley & Sons
Release : 2017-10-23
ISBN : 1119109841
Language : En, Es, Fr & De

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Book Description :

The first comprehensive guide to research methods and technologies in psycholinguistics and the neurobiology of language Bringing together contributions from a distinguished group of researchers and practitioners, editors Annette M. B. de Groot and Peter Hagoort explore the methods and technologies used by researchers of language acquisition, language processing, and communication, including: traditional observational and behavioral methods; computational modelling; corpus linguistics; and virtual reality. The book also examines neurobiological methods, including functional and structural neuroimaging and molecular genetics. Ideal for students engaged in the field, Research Methods in Psycholinguistics and the Neurobiology of Language examines the relative strengths and weaknesses of various methods in relation to competing approaches. It describes the apparatus involved, the nature of the stimuli and data used, and the data collection and analysis techniques for each method. Featuring numerous example studies, along with many full-color illustrations, this indispensable text will help readers gain a clear picture of the practices and tools described. Brings together contributions from distinguished researchers across an array of related disciplines who explain the underlying assumptions and rationales of their research methods Describes the apparatus involved, the nature of the stimuli and data used, and the data collection and analysis techniques for each method Explores the relative strengths and weaknesses of various methods in relation to competing approaches Features numerous real-world examples, along with many full-color illustrations, to help readers gain a clear picture of the practices and tools described

Infant Pathways to Language

Infant Pathways to Language Book
Author : John Colombo,Peggy McCardle,Lisa Freund
Publisher : Psychology Press
Release : 2012-09-10
ISBN : 1136678514
Language : En, Es, Fr & De

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Book Description :

The recent progress in cognitive neuroscience, and the importance of genetic factors and gene-environment interactions in shaping behavioral functions in early childhood, have both underscored the primacy of early experience and development on brain development and function. The contributors to this volume discuss different paradigms and approaches in infant language and cognition, pushing the frontiers of research by innovatively combining methods, introducing new measures, and demonstrating the use of technologies and measurement approaches that can inform the study of word learning and categorization, gaze, attention, gesture, and physiological functions. The volume offers a blend of theories and empirical evidence to support, refute, or modify them. Most chapters examine the link between theory and methodology, and their appearance together in a single volume serves to inform and engage multiple disciplines, to engage everyone to think across disciplines and paradigms, to embrace the integration of creativity and science as the field continues to study in greater depth and with innovative measures and approaches, the infant pathways to language. The volume is essential reading for a wide range of students, researchers, and professionals with an interest in infant cognitive and language development.

Developmental Psychopathology Risk Disorder and Adaptation

Developmental Psychopathology  Risk  Disorder  and Adaptation Book
Author : Dante Cicchetti,Donald J. Cohen
Publisher : John Wiley & Sons
Release : 2006-02-27
ISBN : 0470050063
Language : En, Es, Fr & De

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Book Description :

Developmental Psychopathology, Volume 3, Risk, Disorder, and Adaptation provides a life span developmental perspective on "high-risk" conditions and mental disorders. Moreover, it examines developmental pathways to resilient adaptation in the face of adversity.

Developmental Psychopathology Theory and Method

Developmental Psychopathology  Theory and Method Book
Author : Donald J. Cohen
Publisher : John Wiley & Sons
Release : 2006-04-18
ISBN : 0471755990
Language : En, Es, Fr & De

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Book Description :

Developmental Psychopathology, Second Edition, contains in three volumes the most complete and current research on every aspect of developmental psychopathology. This seminal reference work features contributions from national and international expert researchers and clinicians who bring together an array of interdisciplinary work to ascertain how multiple levels of analysis may influence individual differences, the continuity or discontinuity of patterns and the pathways by which the same developmental outcomes may be achieved. This volume addresses theoretical perspectives and methodological issues, including cross-cultural perspectives, developmental epidemiology, self determination theory, and gender issues.