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Molecular Advancements In Tropical Diseases Drug Discovery

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Molecular Advancements in Tropical Diseases Drug Discovery

Molecular Advancements in Tropical Diseases Drug Discovery Book
Author : Gauri Misra,Vijay Kumar Srivastava
Publisher : Academic Press
Release : 2020-05-12
ISBN : 0128213973
Language : En, Es, Fr & De

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Book Description :

Molecular Advancements in Tropical Diseases Drug Discovery presents in-depth knowledge relating to the detection of infection, epidemiology, drugs against various tropical diseases, new target sites for drug discovery and multidrug resistance issues using bioinformatics tools and approaches. The book's chapters are written by experts in their respective fields so that each disease is covered in a rational manner and with a solid foundation on existing facts and prospective research ideas. Updates knowledge about tropical diseases with recent advancements in the field Presents an overview of new research covering detection, infection, epidemiology and risk factors of the most common tropical diseases using bioinformatics tools Encompasses a detailed description of developments in drug discovery, new drugs and their molecular mechanisms of action

Neglected Tropical Diseases and Phytochemicals in Drug Discovery

Neglected Tropical Diseases and Phytochemicals in Drug Discovery Book
Author : Chukwuebuka Egbuna,Muhammad Akram,Jonathan Chinenye Ifemeje
Publisher : John Wiley & Sons
Release : 2021-11-09
ISBN : 1119616603
Language : En, Es, Fr & De

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Book Description :

NEGLECTED TROPICAL DISEASES AND PHYTOCHEMICALS IN DRUG DISCOVERY Explore novel drug discovery updates from medicinal plants to help fight the devastating effects of neglected tropical diseases Neglected Tropical Diseases and Phytochemicals in Drug Discovery delivers a comprehensive exploration of the drug discovery process as it pertains to neglected tropical diseases. The book covers recent advancements in drug discovery, as well as druggable targets and new challenges facing the industry. It offers readers expansive discussions of specific diseases, including protozoan, helminth, bacterial, viral, fungal, and ectoparasitic infections. This book provides readers with insightful perspectives from leading industry voices on fifty years of trends and progress in the search for new, safe, and affordable therapeutic drugs in the fight against neglected tropical diseases. It includes information beneficial to researchers in a variety of fields of biology, chemistry, medicine, and pharmaceuticals. The distinguished authors cover topics including the effects of phytochemicals on the causative agent of leprosy and the potential applicability of phytochemicals in the management of Dengue fever. Readers will also enjoy the inclusion of: Thorough introductions to neglected tropical diseases, phytochemicals, protein targets, and mechanisms in drug discovery, as well as the epidemiology of neglected tropical diseases An exploration of novel bioactive lead compounds for drug discovery against neglected tropical diseases, leishmaniasis, lymphatic filariasis, trypanosomiasis, and schistosomiasis Discussions of protozoan infections, including herbal, nutritional, and traditional remedies for giardiasis and the anti-leishmanial potentials of phytochemicals Examinations of helminth infections, including the prospects of phytochemicals in the treatment of helminthiasis Perfect for medicinal chemists, drug developers, and research and development scientists, Neglected Tropical Diseases and Phytochemicals in Drug Discovery will also earn a place in the libraries of toxicologists and researchers in biology, chemistry, medicinal chemistry, ethnobotany, and bioinformatics seeking a one-stop resource for drug discovery for neglected tropical diseases.

Drug Discovery for Leishmaniasis

Drug Discovery for Leishmaniasis Book
Author : Carmen Gil
Publisher : Royal Society of Chemistry
Release : 2017-11-02
ISBN : 1782628894
Language : En, Es, Fr & De

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Book Description :

For human health, leishmaniasis is among the most important protozoan diseases, superseded only by malaria. Globally, 10 to 12 million people are infected with 1.5 million new cases every year. The development of cheaper new drugs is urgently needed for this neglected disease that is developing resistance to current treatments. Chemotherapy remains the only treatment option for the bulk of patients. However, this is largely unaffordable for most. In the past three years numerous advances in drug discovery have been made for treating this disease by exploiting diverging metabolic pathways between the Leishmania enzymes and their hosts, using nanotechnology to target the immune cell phagolysosomes where Leishmania resides. Drug Discovery for Leishmaniasis aims to provide a perspective of the current treatments and their challenges, blended with the emerging strategies and methodologies that will drive new target appraisals and drug developments, as well as addressing the molecular basis of resistance in Leishmania. Recent studies have shown that leishmaniasis affects some of the poorest people in the world, with 95% of fatal cases occurring in only 6 countries. With the WHO goal of eliminating this public health problem in the South-east Asia Region by 2020, this book will be important for anyone who is interested in neglected tropical diseases.

Current Topics and Emerging Issues in Malaria Elimination

Current Topics and Emerging Issues in Malaria Elimination Book
Author : Anonim
Publisher : BoD – Books on Demand
Release : 2021-07-21
ISBN : 1839684836
Language : En, Es, Fr & De

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Book Description :

Malaria is one of the most important tropical diseases in the history of the world. This vector-borne disease has been a significant cause of morbidity and mortality in tropical countries of Africa, Asia, and Latin America. As such, this book provides updated information on epidemiological and public health research of malaria conducted in the last decade. Over four sections, chapters discuss such topics as diagnosis, epidemiology and surveillance, policy and prevention, and vector control and vaccines.

Design of Hybrid Molecules for Drug Development

Design of Hybrid Molecules for Drug Development Book
Author : Michael Decker
Publisher : Elsevier
Release : 2017-04-05
ISBN : 0081011180
Language : En, Es, Fr & De

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Book Description :

Design of Hybrid Molecules for Drug Development reviews the principles, advantages, and limitations involved with designing these groundbreaking compounds. Beginning with an introduction to hybrid molecule design and background as to their need, the book goes on to explore a range of important hybrids, with hybrids containing natural products, molecules containing NO- and H2S-donors, dual-acting compounds acting as receptor ligands and enzyme inhibitors, and the design of photoresponsive drugs all discussed. Drawing on practical case studies, the hybridization of molecules for development as treatments for a number of key diseases is then outlined, including the design of hybrids for Alzheimer's, cancer, and malaria. With its cutting-edge reviews of breaking developments in this exciting field, the book offers a novel approach for all those working in the design, development, and administration of drugs for a range of debilitating disorders. Highlights an approach unimpaired by the limitations of the classical search for lead structures - one of the core problems in modern drug development processes, making the content of high relevance for both academic and non-academic drug development processes Pulls together research and design techniques in a novel way to give researchers the best possible platform from which to review the approaches and techniques applied Compares the advantages and disadvantages of these compounds Includes the very latest developments, such as photoactivatable and photo-responsive drugs

Medicinal Chemistry of Neglected and Tropical Diseases

Medicinal Chemistry of Neglected and Tropical Diseases Book
Author : Venkatesan Jayaprakash,Daniele Castagnolo,Yusuf Özkay
Publisher : CRC Press
Release : 2019-08-15
ISBN : 1351011634
Language : En, Es, Fr & De

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Book Description :

Medicinal Chemistry of Neglected and Tropical Diseases: Advances in the Design and Synthesis of Antimicrobial Agents consolidates and describes modern drug discovery and development approaches currently employed to identify effective chemotherapeutic agents for the treatment of Neglected Tropical Diseases (NTDs) from a medicinal chemistry perspective. Chapters are designed to cater to the needs of medicinal chemists who work with chemotherapeutic developments for NTDs, as well as serve as a guide to budding medicinal chemists who wish to work in this area. It will introduce rational drug design approaches adopted in designing chemotherapeutics and validated targets available for the purpose.

Drug Discovery and Development

Drug Discovery and Development Book
Author : Omboon Vallisuta,Suleiman Olimat
Publisher : BoD – Books on Demand
Release : 2015-06-03
ISBN : 9535121286
Language : En, Es, Fr & De

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Book Description :

It is very important for scientists all over the globe to enhance drug discovery research for better human health. This book demonstrates that various expertise are essential for drug discovery including synthetic or natural drugs, clinical pharmacology, receptor identification, drug metabolism, pharmacodynamic and pharmacokinetic research. The following 5 sections cover diverse chapter topics in drug discovery: Natural Products as Sources of Leading Molecules in Drug Discovery; Oncology and Drug Discovery; Receptors Involvement in Drug Discovery; Management and Development of Drugs against Infectious Diseases; Advanced Methodology.

Proceedings of 2nd International Conference on Advances in Chemical Engineering Technology 2017

Proceedings of 2nd International Conference on Advances in Chemical Engineering   Technology 2017 Book
Author : ConferenceSeries
Publisher : ConferenceSeries
Release : 2023-01-27
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

November 16-17, 2017 Paris, France key Topics : Chemical engineering, Catalysis Engineering, Biologically Engineered Systems, Bio Fuels, Biotechnology, Biomaterials, Water Technology and Innovation, Polymer Technology, Thermodynamic Process, Seperation Techniques, Biochemical Engineering, Transport Phenomenon, Fluid Dynamics, Chemical reaction Engineering, Petroleum Engineering, Safety Methods, Enterpreneurship Investment Meet, Carbon and Graphene Materials, Environmental Engineering,

Proceedings of 3rd International Conference and Exhibition on Advances in Chromatography HPLC Techniques 2017

Proceedings of 3rd International Conference and Exhibition on Advances in Chromatography   HPLC Techniques 2017 Book
Author : ConferenceSeries
Publisher : ConferenceSeries
Release : 2023-01-27
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

July 13-14, 2017 Berlin, Germany Key Topics : Major Chromatographic Techniques, HPLC Separation Techniques, Advances in HPLC Instrumentations, Hyphenated HPLC Methods, Chip Based Separations, High Efficiency and High Resolution Techniques, Method Development and Validation, Applications of HPLC, Biochemical Applications, HPLC Fingerprinting in Bioinformatics and Computational Biology, Recent Advances in HPLC, Market growth of HPLC

Imidazole Based Drug Discovery

Imidazole Based Drug Discovery Book
Author : Shikha Agarwal
Publisher : Elsevier
Release : 2021-12-10
ISBN : 0323903630
Language : En, Es, Fr & De

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Book Description :

Imidazole-Based Drug Discovery covers all categories of imidazole and its derivatives, synthesis, pharmacological applications and drug-based studies. Imidazole scaffolds act as a channel between organic synthesis and medicinal chemistry and compel researchers to explore new drug candidates. This book provides detailed coverage of several greener synthetic protocols and pharmacological applications of imidazole derivatives that are useful to researchers working on designing more promising clinical lead compounds with this scaffold. It also includes information on past decades of research on the synthesis and biological applications of imidazole derivatives. This is an ideal resource for researchers in organic chemistry both in academic and industrial settings, as well as postgraduates in chemistry and medicinal chemistry. Reviews the most current developments and future perspectives of imidazole on different disease therapies to achieve the ultimate goal of disease eradication Discusses the role of imidazole in contemporary science, technological innovation, drug development, critical challenges and future research directions Covers emerging trends on different eco-benign pathways to synthesize imidazole derivatives for the development of simpler synthetic protocols

Pathogenesis Treatment and Prevention of Leishmaniasis

Pathogenesis  Treatment and Prevention of Leishmaniasis Book
Author : Mukesh Samant,Satish Chandra Pandey
Publisher : Academic Press
Release : 2021-08-18
ISBN : 0128227982
Language : En, Es, Fr & De

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Book Description :

Leishmaniasis is a neglected tropical disease that is known to be transmitted by 90 different species of sandflies which carry 20 Leishmania species that cause human infection particularly in endemic countries. Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to provide information on this vector-borne disease and explore strategies for diagnosis and treatment. The book begins with an overview of leishmaniasis which includes historical and future perspectives of the disease. It also discusses the clinical manifestation of the disease, mechanisms of infection, therapeutic strategies, diagnostics, prevention, and cure of Leishmania parasite. The book goes on to explain new insights and challenges in the development of promising drug targets, biomarkers identification and advance vaccination strategies against leishmaniasis. Chapter contributions brings together diverse areas of expertise making Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to bring together elements of leishmaniasis into one place and be a valuable resource for researchers, health care professionals, and graduate students, working in the field of leishmaniasis. Provides an overview Leishmania and leishmanisis which include its history, transmission, clinical picture, and treatment Discusses novel approaches to study parasite infection and treatment Explores recent advances in the development of diagnostic kits, drug development and various vaccination strategies

Proceedings of 6th World Congress on Medicinal Chemistry and Drug Design 2017

Proceedings of 6th World Congress on Medicinal Chemistry and Drug Design 2017 Book
Author : ConferenceSeries
Publisher : ConferenceSeries
Release : 2017-06-01
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

June 07-08, 2017 Milan,. Italy Key Topics : Medicinal Chemistry, Synthetic Organic Chemistry, Drug Design and Drug Development, CADD (Computer Aided Drug Design), Bioorganic and Medicinal Chemistry, Pharmacology and toxicology, BioInorganic Chemistry, Organometallic Chemistry, Radiopharmaceuticals, Chemical Biology, Anticancer agents in Medicinal Chemistry, Pharmaceutical Industry, Clinical Pharmacology, Pharmaceutical Sciences, Bioisostere, Analytical Chemistry, Nanomedicine, Stereochemistry, Pharmacovigilance,

Proceedings of 6th Euro Global Conference on Infectious Diseases 2017

Proceedings of 6th Euro Global Conference on Infectious Diseases 2017 Book
Author : ConferenceSeries
Publisher : ConferenceSeries
Release : 2023-01-27
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

September 07-09, 2017 Paris, France Key Topics : Viral Infectious Diseases, Bacterial Infectious Diseases, Ebola Outbreak and Approaches for Prevention, Fungal Infectious Diseases, New Antiviral, Antibacterial and Antifungal Agents, Market Trends Of Infectious Diseases, Parasitic Diseases, Bacterial Susceptibility & Resistance, Nosocomial Infections, Detection and preventing infections in healthcare, Public health practice, Vaccines, Respiratory Diseases, Infectious Agents and the Human Immune Response, Infectious Diseases: Worms, Prions, and Fungi, Protozoal Diseases, Clinical Infectious Disease, Infectious Disease Epidemiology, Emerging Infectious Diseases, Laboratory Diagnosis of Infectious Diseases, Infectious Diseases of Humans, Infectious Diseases and Pathology, Microbiology and Infectious Diseases, Infectious Diseases of Livestock, Infectious Diseases of the Female Genital Tract, Molecular Diagnostics of Infectious Diseases, Pediatric Infectious Diseases, Bacterial Genomes and Infectious Diseases:, Drug Interactions in Infectious Diseases, Infectious Diseases in Children, Medical Pioneers in Infectious Diseases, Infectious Diseases and Tropical Medicine, Infectious Diseases in Critical Care Medicine, Infectious Diseases and Arthropods, Preventing Infectious Diseases, Feline Infectious Diseases, Tropical Infectious Diseases, Infectious Diseases in America, Infectious Diseases in Europe, Infectious Diseases in UK, Infectious Diseases in Asia, Infectious Diseases in Africa, Sexually transmitted Diseases and infection,

Proceedings of 4th International congress on Infectious Diseases 2017

Proceedings of 4th International congress on Infectious Diseases 2017 Book
Author : ConferenceSeries
Publisher : ConferenceSeries
Release : 2023-01-27
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

May 11-12, 2017 Barcelona, Spain Key Topics : Infection and Immune System, Host and Microbial Genetics, Infections from Contaminated Pharmaceuticals or Counterfeit Medications, Foodborne & Waterborne Illnesses, Nosocomial Infections, Pediatric Infections, Emergence and Pathogenesis of Coronaviruses, Hemorrhagic Fevers, New or Rapid Diagnostics, Therapeutic Interventions in Rare Diseases, Antimicrobial Resistance, Drug metabolism in microorganisms, Infection Control and Epidemiology, New Opportunities for Tuberculosis Control,

Proceedings of 20th International Conference on Advanced Energy Materials and Research 2018

Proceedings of 20th International Conference on Advanced Energy Materials and Research 2018 Book
Author : ConferenceSeries
Publisher : ConferenceSeries
Release : 2018-08-07
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

August 13-14 2018 Dublin, Ireland Key Topics : Advanced Energy Materials, Hydrogen Energy, Solar Energy Materials, Polymer Materials, Advanced Nanomaterials, Energy Harvesting Materials, Nanotechnology and Energy Materials, Batteries and Energy Materials, Electric, Hybrid, and Fuel-Cell Vehicles, Mining, Metallurgy & Materials Science, Advanced Graphene Materials, Solid Electrolytes, Biomaterials and Surface Science Engineering, Electrical, Optical and Magnetic Materials, Fuel Cell Technology,

Proceedings of Health Economics Policy Outcomes Research 2017

Proceedings of Health Economics Policy   Outcomes Research 2017 Book
Author : ConferenceSeries
Publisher : ConferenceSeries
Release : 2023-01-27
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

June 29-30, 2017 Madrid, Spain Key Topics : Health Economics, Health Economics and Policy, Health Economics and Health Care Services, Health Economics and Pharmaceutical Manufacturers, Health Economics and Health Insurance, Health Economics and Outcome Research, Health Economics and Econometrics, Health Economics and Health Statistics, Health Economics Modelling, Health Economics and Behavioural economics, Health Economics and Public health economics, Health Economics and Health care Markets, Health Economics and Financing, Health Economics and International Economics, Health care services and insurance, Economics of Health innovation, Hospital Services, Outcome Research and Epidemiology, Economic Epidemiology, Health Economics and Macroeconomics,

Proceedings of 2nd World Congress on Medical Imaging and Clinical Research 2017

Proceedings of 2nd World Congress on Medical Imaging and Clinical Research 2017 Book
Author : ConferenceSeries
Publisher : ConferenceSeries
Release : 2017-09-05
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

September 11-12, 2017 Paris, France Key Topics : Industrial Forum of Radiology, Medical Image Processing, Ophthalmic Imaging, Radiography, Radiology and Nuclear medicine, Computer- assisted tomography, Elastography, Pathology Imaging, Molecular Imaging, Applications of Imaging, Advances in Medical Imaging, Advances in Cancer Imaging and Diagnosis, Fusion of Imaging modalities, Clinical Research and Trials on AIDS / Cancer / Diabetes, Pre-Clinical Research, Future of Clinical Trials, Clinical Data Management and Statistics, Clinical and Medical case reports, Clinical Trial Supply Management, Clinical Trials on different Diseases, Entrepreneurs Investment Meet, Innovations in Clinical Trials, Case Reports and Clinical research on Cardiology, Imaging in Gastroenterology, Cardiac imaging, Dentistry Imaging, Dentistry Clinical Research, Pediatric Radiology, Neuroradiology, Clinical Research on Neuroscience, Clinical Research’s on Gastroenterology,

Proceedings of 7th Annual Congress on Materials Research and Technology 2017

Proceedings of 7th Annual Congress on Materials Research and Technology 2017 Book
Author : ConferenceSeries
Publisher : ConferenceSeries
Release : 2017-02-14
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

February 20-21, 2017 Berlin, Germany Key Topics : Materials Science and Engineering, Nanotechnology, Biomaterials and Healthcare, Materials in Industry, Materials Chemistry, Materials Physics, Energy Materials, Metallurgy and Materials Science, Advanced Materials and Devices, Characterization and Testing of Materials, Entrepreneurs Investment Meet,

Proceedings of 3rd International Conference on Advanced Clinical Research and Clinical Trials 2017

Proceedings of 3rd International Conference on Advanced Clinical Research and Clinical Trials 2017 Book
Author : ConferenceSeries
Publisher : ConferenceSeries
Release : 2023-01-27
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

September 20-21, 2017 Dublin, Ireland Key Topics : Innovations in Pre-clinical Research, Stem Cell & Oncology Clinical Research, Design of Clinical Studies and Trials, Conducts of Clinical Trials, Biomedical Devices Clinical Research, Clinical Research and Trials on AIDS, Clinical Trials on Different Diseases, Clinical Data Management and Statistics, Clinical Trials in Developing Countries, Innovations in Clinical Trials, Future of Clinical Trials, GCP Learning and Best Practices, Risk Management at Research Site, Bioethics and Quality Regulation, Pharmacovigilance and Drug Safety, Clinical and Medical Case Reports, Transforming Trial Methodologies, Diabetes & Gastroenterology Clinical Research, Current Regulatory Trends in Drug Development, Clinical Nursing Research,

Proceedings of 2nd International Conference and Exhibition on Marine Drugs Natural Products 2017

Proceedings of 2nd International Conference and Exhibition on Marine Drugs   Natural Products 2017 Book
Author : ConferenceSeries
Publisher : ConferenceSeries
Release : 2017-06-09
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

June 15-17, 2017 London, UK Key Topics : Natural Products, New Sources and Approaches to Natural Products, Natural Products Chemistry, Natural Products Drug Discovery, Phytomedicine and Phytochemistry, Medicinal Natural Products, Natural Products as Anti-Cancer Drugs, Marine: The Ultimate Source of Bioactives and Drug Metabolites, Marine Biotechnology, Marine Natural Products Drug Discovery, Development of Marine Drugs and Natural Products, Bioactive Natural Products, Bioactive Natural Products from Marine Bacteria, Marine Probiotics and Prebiotics, A Promising Future for Marine Drugs and Natural Products, Entrepreneurs Investment Meet,