Modern Applications Of Plant Biotechnology In Pharmaceutical Sciences

Book Description :

Modern Applications of Plant Biotechnology in Pharmaceutical Sciences explores advanced techniques in plant biotechnology, their applications to pharmaceutical sciences, and how these methods can lead to more effective, safe, and affordable drugs. The book covers modern approaches in a practical, step-by-step manner, and includes illustrations, examples, and case studies to enhance understanding. Key topics include plant-made pharmaceuticals, classical and non-classical techniques for secondary metabolite production in plant cell culture and their relevance to pharmaceutical science, edible vaccines, novel delivery systems for plant-based products, international industry regulatory guidelines, and more. Readers will find the book to be a comprehensive and valuable resource for the study of modern plant biotechnology approaches and their pharmaceutical applications. Builds upon the basic concepts of cell and plant tissue culture and recombinant DNA technology to better illustrate the modern and potential applications of plant biotechnology to the pharmaceutical sciences Provides detailed yet practical coverage of complex techniques, such as micropropogation, gene transfer, and biosynthesis Examines critical issues of international importance and offers real-life examples and potential solutions

Book Description :

This book provides a summarized information related to the global herbal drug market and its regulations, ethnopharmacology of traditional crude drugs, isolation of phytopharmaceuticals, phytochemistry, standardization, and quality assessment of crude drugs. Natural products science has constantly been developing with comprehensive data contemplating different parts of natural drugs, such as global trade, quality control and regulatory concerns, traditional medicine systems, production and utilization of drugs, and utilization of medicinal and aromatic plants. This broad information about crude drugs gives rise to a subject that is now recognized as advance natural products science. By contemplating all of this thorough knowledge of the areas, this book is intended to provide considerably to the natural products science. The area of natural products science involves a broad range of topics, such as the pharmacognostical, phytochemical, and ethno-pharmacological aspects of crude drugs. Each chapter gives a sufficient understanding to academicians and researchers in the respective topic. This book includes 40 illustrations and descriptions of roughly 80 medicinal plants used for herbal medicine. The book is an imperative source for all researchers, academicians, students, and those interested in natural products science. FEATURES Includes advance knowledge and detailed developments in natural products science Discusses the most important phytopharmaceuticals used in the pharmaceutical industry Explores the analysis and classification of novel plant-based medicinal compounds Includes standardization, quality control, and global trade of natural products Gives a deep understanding related to recent advances in herbal medicines to treat various ailments Discusses national and WHO regulations and policies related to herbal medicines Covers the complete profile of some important traditional medicinal plants, especially their historical background, biology, and chemistry

Book Description :

Coronavirus disease 2019 (COVID-19) has emerged as a global health threat. Unfortunately, there are very limited approved therapeutics available with established efficacy and safety profiles against SARS-CoV-2. COVID-19 vaccines aim to actively induce systemic immunization; however, the possibility or fear of side effects decreases or discourages their use. Alternative therapy via natural products, especially essential oils, could be considered safe and effective to improve health, cure ailments, and soothe your body and mind. Essential oils, which have been known for their anti-inflammatory, immunomodulatory, bronchodilatory, and antiviral properties, could possibly be useful for the symptomatic management of COVID-19. This book is vital in respect of designing approaches to protect humanity from further losses and harm due to SARS-CoV-2 infection. Role of Essential Oils in the Management of COVID-19 offers a complete outline of the recent novel coronavirus (SARS-CoV-2) infection, its biology, and associated challenges for the prevention and treatment of novel COVID-19, with a prime focus on the possible role of essential oils in the prevention and treatment of COVID-19. This book is written for everyone who needs to be thoroughly familiar with the appropriate and safe use of essential oils in COVID-19 therapy. As per the objectives of the book: The first seven chapters cover various aspects of COVID-19 infection, including epidemiology, origin, morphology, genome organization, pathogenesis, clinical manifestations, diagnostic approaches, preventive measures, and treatment strategies. The remaining chapters elaborate on the various aspects related to essential oils, such as chemistry, extraction methods, dispensing methods, stability, quality control, mechanism of action, therapeutic effects, pharmacokinetics, aromatherapy, and safety profiles. Prof. Ahmed Al-Harrasi is Vice Chancellor for Graduate Studies, Research and External Relations, Natural and Medical Sciences Research Center, and Professor of Organic Chemistry, University of Nizwa, Oman. Prof. Ahmed received his M.Sc. degree in Chemistry followed by his Ph.D. in Organic Chemistry from the University of Berlin. He then pursued his postdoctoral research at Cornell University. Afterward, he continued his research rigor at the University of Nizwa, where he founded the Natural and Medical Sciences Research Center, which has now become a center of excellence in natural and medical sciences. While enduring his research aptitude, he has authored and co-authored more than 400 scientific papers, 2 books, and 12 book chapters of high repute. Dr. Saurabh Bhatia graduated from Kurukshetra University, followed by postgraduation from Bharati Vidyapeeth University. He received his Ph.D in Pharmaceutical Technology at Jadavpur University. He now works as an Associate Professor at Natural and Medical Sciences Research Center, University of Nizwa, Oman. He has 12 years of academic experience; has authored 75 articles and 9 books of repute; and filed 11 patents.

Book Description :

This book details current developments in all natural polymers, with a focus on animal and microbial polysaccharides. The book examines, compares, and contrasts the efficiency of plant and algae based natural polymers in inducing immune reactions. Additionally, the book details the safety and toxicity profiles with respective regulations.

Book Description :

Pharmaceutical Biotechnology offers students taking Pharmacy and related Medical and Pharmaceutical courses a comprehensive introduction to the fast-moving area of biopharmaceuticals. With a particular focus on the subject taken from a pharmaceutical perspective, initial chapters offer a broad introduction to protein science and recombinant DNA technology- key areas that underpin the whole subject. Subsequent chapters focus upon the development, production and analysis of these substances. Finally the book moves on to explore the science, biotechnology and medical applications of specific biotech products categories. These include not only protein-based substances but also nucleic acid and cell-based products. introduces essential principles underlining modern biotechnology- recombinant DNA technology and protein science an invaluable introduction to this fast-moving subject aimed specifically at pharmacy and medical students includes specific ‘product category chapters’ focusing on the pharmaceutical, medical and therapeutic properties of numerous biopharmaceutical products. entire chapter devoted to the principles of genetic engineering and how these drugs are developed. includes numerous relevant case studies to enhance student understanding no prior knowledge of protein structure is assumed

Book Description :

This book describes 200 bio-polymers, including the most recent and advanced nanotechnology applications. The applications of various bio-medical and other future potential uses are covered and examined in depth. Systematic discussion of current leading natural polymers is also included.

Book Description :

This book presents latest work in the field of plant biotechnology regarding high-efficiency micropropagation for commercial exploitation at low labor and equipment costs. The book consists of 18 chapters on establishing advanced culture systems, techniques as well as latest modification protocols on a variety of crops. It also discusses new methods such as nylon film culture system, light-emitting diode and wireless light-emitting diode system, stem elongation, wounding manipulation and shoot tip removal, in vitro hydroponic and microponic culture system, thin cell layer culture system etc. Plant cell tissue has been developed more than fifty years ago. Since then applications of in vitro plant propagation expanded rapidly all around the world and played as an important role in agricultural and horticultural systems. This book will be of interest to teachers, researchers, scientists, capacity builders and policymakers. Also the book serves as additional reading material for undergraduate and graduate students of agriculture, forestry, ecology, soil science, and environmental sciences.

Book Description :

This volume presents chapters that discuss secondary metabolites of marine origin, the industrial applications of phytochemicals, and recent advances in phytochemical research. It considers production of secondary metabolites and accumulations through in vitro cultures and also reviews the effects of natural products as biopesticides and as eco-friendly corrosion inhibitors. In addition, the volume discusses the effects of the environment on the distribution of phytochemicals and the roles of phytochelatins and heavy metal tolerance in plants.

Book Description :

Natural bioactive compounds have become an integral part of plant-microbe interactions geared toward adaptation to environmental changes. They regulate symbiosis, induce seed germination, and manifest allelopathic effects, i.e., they inhibit the growth of competing plant species in their vicinity. In addition, the use of natural bioactive compounds and their products is considered to be suitable and safe in e.g. alternative medicine. Thus, there is an unprecedented need to meet the increasing demand for plant secondary metabolites in the flavor and fragrance, food, and pharmaceutical industries. However, it is difficult to obtain a constant quantity of compounds from the cultivated plants, as their yield fluctuates due to several factors including genotypic variations, the geography, edaphic conditions, harvesting and processing methods. Yet familiarity with these substances and the exploration of various approaches could open new avenues in their production. This book describes the basis of bioactive plant compounds, their mechanisms and molecular actions with regard to various human diseases, and their applications in the drug, cosmetic and herbal industries. Accordingly, it offers a valuable resource for students, educators, researchers, and healthcare experts involved in agronomy, ecology, crop science, molecular biology, stress physiology, and natural products.

Book Description :

Advances in Plant Tissue Culture: Current Developments and Future Trends provides a complete and up-to-date text on all basic and applied aspects of plant tissue cultures and their latest application implications. It will be beneficial for students and early-career researchers of plant sciences and plant/agricultural biotechnology. Plant tissue culture has emerged as a sustainable way to meet the requirements of fresh produces, horticultural crops, medicinal or ornamental plants. Nowadays, plant tissue culture is an emerging filed applied in various aspects, including sustainable agriculture, plant breeding, horticulture and forestry. This book covers the latest technology, broadly applied for crop improvement, clonal propagation, Somatic hybridization Embryo rescue, Germplasm conservation, genetic conservation, or for the preservation of endangered species. However, these technologies also play a vital role in breaking seed dormancy over conventional methods of conservation. Focuses on plant tissue culture as an emerging field applied in various aspects, including sustainable agriculture, plant breeding, horticulture and forestry Includes current studies and innovations in biotechnology Covers commercialization and current perspectives in the field of plant tissue culture techniques

Book Description :

This book is a unique overview of insights on the genetic basis of anti-diabetic activity, chemistry, physiology, biotechnology, mode-of-action, as well as cellular mechanisms of anti-diabetic secondary metabolites from medicinal plants. The World Health Organization estimated that 80% of the populations of developing countries rely on traditional medicines, mostly plant drugs, for their primary health care needs. There is an increasing demand for medicinal plants having anti-diabetic potential in both developing and developed countries. The expanding trade in medicinal plants has serious implications on the survival of several plant species, with many under threat to become extinct. This book describes various approaches to conserve these genetic resources. It discusses the whole spectrum of biotechnological tools from micro-propagation for large-scale multiplication, cell-culture techniques to the biosynthesis and enhancement of pharmaceutical compounds in the plants. It also discusses the genetic transformation as well as short- to long-term conservation of plant genetic resources via synthetic seed production and cryopreservation, respectively. The book is enriched with expert contributions from across the globe. This reference book is useful for researchers in the pharmaceutical and biotechnological industries, medicinal chemists, biochemists, botanists, molecular biologists, academicians, students as well as diabetic patients, traditional medicine practitioners, scientists in medicinal and aromatic plants, Ayurveda, Siddha, Unani and other traditional medical practitioners.

Book Description :

Adopting a unique approach, this novel textbook integrates science and business for an inside view on the biotech industry. Peering behind the scenes, it provides a thorough analysis of the foundations of the present day industry for students and professionals alike: its history, its tools and processes, its markets and products. The authors, themselves close witnesses of the emergence of modern biotechnology from its very beginnings in the 1980s, clearly separate facts from fiction, looking behind the exaggerated claims made by start-up companies trying to attract investors. Essential reading for every student and junior researcher looking for a career in the biotech sector.

Book Description :

Plant tissue culture (PTC) technology has gained unassailable success for its various commercial and research applications in plant sciences. Plant growth regulators (PGRs) are an essential part of any plant tissue culture intervention for propagation or modification of plants. A wide range of PGRs are available, including aromatic compounds that show cytokinin activities, promote cell division and micro-propagation, viz. kinetin, N6-benzyladenine and topolins. Topolins are naturally occurring aromatic compounds that have gained popularity as an effective alternative for other frequently used cytokinins in in vitro culture of plants. Among them, meta-topolin [6-(3-hydroxybenzlyamino) purine] is the most popular and its use in plant tissue culture has amplified swiftly. During the last few decades, there have been numerous reports highlighting the effectiveness of meta-topolin in micropropagation and alleviation of various physiological disorders, rooting and acclimatization of tissue culture raised plants.

Book Description :

This important new book provides the fundamental understanding of the peptide and protein drug delivery systems with a special focus on their nanotechnology applications. Addressing an increasing interest in peptide and protein drug delivery systems in both academic and industrial circles worldwide, this book fills the need for a comprehensive review and assessment of conventional and nonconventional routes of administration.

Book Description :

This book deals with a subject of high interest and importance in all sectors, including biomedical, food, agriculture, energy, and environment. Biological systems are essential in nanotechnology, and many new applications are being developed by mimicking the natural systems. Approaching these topics from an engineering perspective, the book offers insight on the details of nanoscale fabrication processes as well as cell biology. The basics of biology and chemistry, with a focus on how to engineer the behavior of molecules at the nanoscale, are also explored and analyzed. The aim of the text is to provide the reader with broader knowledge of biological methods for signal transduction and molecular recognitions systems and how they can be replicated in bio-sensing applications. The reader will learn the basic structures and interactions of biomacromolecules for developing biocompatible and eco-friendly devices.

Book Description :

PLANTS AS BIOREACTORS FOR INDUSTRIAL MOLECULES An incisive and practical discussion of how to use plants as bioreactors In Plants as Bioreactors for Industrial Molecules, a team of distinguished researchers delivers an insightful and global perspective on the use of plants as bioreactors. In the book, you’ll find coverage of the basic, applied, biosynthetic, and translational approaches to the exploitation of plant technology in the production of high-value biomolecules. The authors focus on the yield and quality of amino acids, vitamins, and carbohydrates. The authors explain how high-value biomolecules enable developers to create cost-effective biological systems for the production of biomolecules useful in a variety of sectors. They provide a holistic approach to plant-based biological devices to produce natural molecules of relevance to the health and agriculture industries. Readers will also find: A thorough overview of plants as bioreactors and discussions of molecular farming for the production of pharmaceutical proteins in plants Comprehensive explorations of plants as edible vaccines and plant cell culture for biopharmaceuticals Practical discussions of the production of attenuated viral particles as vaccines in plants and insecticidal protein production in transgenic plants Extensive treatment of the regulatory challenges involved in using plants as bioreactors Perfect for academics, scientists, and researchers in industrial microbiology and biotechnology, Plants as Bioreactors for Industrial Molecules will also earn a place in the libraries of biotechnology company professionals in applied product development.

Book Description :

Precision agriculture integrates new technologies with the agronomic experience to intelligently manage the high spatial variability of all agricultural variables and the time scales at which these variables change. The right application of this approach increases the size and quality of the agricultural production; saves resources; improves environmental quality; helps to achieve self-sufficiency, food security, and agricultural sustainability; increases exports; and more. Precision Agriculture Technologies for Food Security and Sustainability is an essential reference source that compiles a comprehensive, multidisciplinary review of current research in the field of precision agriculture. It also discusses cutting-edge tools and models that can help facilitate and improve the systems implementation. Featuring coverage of a wide range of topics including agronomy, public policy, and internet of things, this book is ideally designed for agriculturalists, government officials, economists, environmentalists, academicians, researchers, students, and engineers in the fields of electronics, ICT, and agriculture.

Book Description :

Fungal nanobionics has great prospects for developing new products with industrial, agriculture, medicine and consumer applications in a wide range of sectors. The fields of chemical engineering, agri-food, biochemical, pharmaceuticals, diagnostics and medical device development all employ fungal products, with fungal nanomaterials currently used in a wide range of applications, ranging from drug development to food industry and agricultural sector. The fungal agents emerge as an environmentally friendly, clean, non‐toxic agent for the biogenic metal nanoparticles and employs both intracellular and extracellular methods. The simplicity of scaling up and downstream processing and the presence of fungal mycelia affording an increased surface area provide key advantages. In addition, the larger spectrum of synthesized nanoparticle morphologies and the substantially faster biosynthesis rate in cell-free filtrate (due to the higher amount of proteins secreted in fungi) make this a particularly enticing route. Understanding the diversity of fungi in assorted ecosystems, as well as their interactions with other microorganisms, animals and plants, is essential to underpin real and innovative technological developments and the applications of metal nanoparticles in many disciplines including agriculture, catalysis, and biomedical biosensors. Importantly, biogenic fungal nanoparticles show significant synergistic characteristics when combined with antibiotics and fungicides to offer substantially greater resistance to microbial growth and applications in nanomedicine ranging from topical ointments and bandages for wound healing to coated stents.

Book Description :

An understanding of crop physiology and ecophysiology enables the horticulturist to manipulate a plant’s metabolism towards the production of compounds that are beneficial for human health when that plant is part of the diet or the source of phytopharmaceutical compounds. The first part of the book introduces the concept of Controlled Environment Horticulture as a horticultural production technique used to maximize yields via the optimization of access to growing factors. The second part describes the use of this production technique in order to induce stress responses in the plant via the modulation of these growing factors and, importantly, the way that this manipulation induces defence reactions in the plant resulting in the production of compounds beneficial for human health. The third part provides guidance for the implementation of this knowledge in horticultural production.

Book Description :

This book examines the development of innovative modern methodologies towards augmenting conventional plant breeding, in individual crops, for the production of new crop varieties under the increasingly limiting environmental and cultivation factors to achieve sustainable agricultural production, enhanced food security, in addition to providing raw materials for innovative industrial products and pharmaceuticals. This Volume 8, subtitled Vegetable Crops: Bulbs, Roots and Tubers, consists of 12 chapters focusing on advances in breeding strategies using both traditional and modern approaches for the improvement of individual vegetable crops. Chapters are arranged in 3 parts according to the edible vegetable parts. Part I: Bulbs - Garlic (Allium sativum L.), Leek (Allium ampeloprasum L.) and Shallot (Allium cepa L. Aggregatum group); Part II: Roots - Beetroot (Beta vulgaris ssp. vulgaris var. conditiva Alefeld), Carrot (Daucus carota L.), Parsnip (Pastinaca sativa L.), Radish (Raphanus sativus L.), Sugar beet (Beta vulgaris ssp. vulgaris L.) and Turnip (Brassica rapa var. rapa L.), Part III: Tubers - Potato (Solanum tuberosum L.) and Sweet potato (Ipomea batatas L.). The chapters were contributed by 38 internationally reputable scientists from 13 countries. Each chapter comprehensively reviews the modern literature on the subject and reflects the authors own experience.