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Modeling The Psychopathological Dimensions Of Schizophrenia

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Modeling the Psychopathological Dimensions of Schizophrenia

Modeling the Psychopathological Dimensions of Schizophrenia Book
Author : Mikhail Pletnikov
Publisher : Academic Press
Release : 2015-12-01
ISBN : 9780128009819
Language : En, Es, Fr & De

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Book Description :

Modeling the Psychopathological Dimensions of Schizophrenia: From Molecules to Behavior is the first book to offer a comprehensive review of the new theoretical, clinical, and basic research framework that considers psychotic illness as a group of dimensional representations of psychopathology rather than as traditional distinct categorical diagnoses. Psychotic illness, typified by schizophrenia, is a devastating condition increasingly recognized as a disorder of abnormal brain development and dysconnectivity. Its complex etiology involves both genetic and environmental factors, as well as the interplay among them. This book describes the current understanding of the clinical and pathological features of schizophrenia, with a particular focus on the evolving conceptualization of schizophrenia and related diagnostic categories of psychotic illness as combinations of dimensional abnormalities. It provides an overview of modern strategies for generating cellular and whole animal models of schizophrenia as well as detailed reviews of the specific experimental preparations and paradigms aimed at molecular, developmental, and brain-network mechanisms that are the underlying aspects of abnormal behavior and various aspects of schizophrenia. This groundbreaking book is an authoritative overview of the translational impact of emerging clinical insights on basic research approaches in schizophrenia that will advance the reader's understanding of the five major dimensions of psychopathology in schizophrenia and related psychoses and resolve the genetic and neurobiological underpinnings of these dimensions. Includes reviews of animal models that capture the most recent insights into the etiology and pathogenetic mechanisms of schizophrenia, with an emphasis on the translational potential of these models Contains a series of reviews of recently available cellular models for analysis of signaling pathways and gene expression, which complement behavioral neuroscience research in schizophrenia Edited and authored by leading researchers in the field of schizophrenia and related psychoses

Modeling the Psychopathological Dimensions of Schizophrenia

Modeling the Psychopathological Dimensions of Schizophrenia Book
Author : Mikhail Pletnikov,John Waddington
Publisher : Academic Press
Release : 2015-11-05
ISBN : 012801184X
Language : En, Es, Fr & De

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Book Description :

Modeling the Psychopathological Dimensions of Schizophrenia: From Molecules to Behavior is the first book to offer a comprehensive review of the new theoretical, clinical, and basic research framework that considers psychotic illness as a group of dimensional representations of psychopathology rather than as traditional distinct categorical diagnoses. Psychotic illness, typified by schizophrenia, is a devastating condition increasingly recognized as a disorder of abnormal brain development and dysconnectivity. Its complex etiology involves both genetic and environmental factors, as well as the interplay among them. This book describes the current understanding of the clinical and pathological features of schizophrenia, with a particular focus on the evolving conceptualization of schizophrenia and related diagnostic categories of psychotic illness as combinations of dimensional abnormalities. It provides an overview of modern strategies for generating cellular and whole animal models of schizophrenia as well as detailed reviews of the specific experimental preparations and paradigms aimed at molecular, developmental, and brain-network mechanisms that are the underlying aspects of abnormal behavior and various aspects of schizophrenia. This groundbreaking book is an authoritative overview of the translational impact of emerging clinical insights on basic research approaches in schizophrenia that will advance the reader’s understanding of the five major dimensions of psychopathology in schizophrenia and related psychoses and resolve the genetic and neurobiological underpinnings of these dimensions. Includes reviews of animal models that capture the most recent insights into the etiology and pathogenetic mechanisms of schizophrenia, with an emphasis on the translational potential of these models Contains a series of reviews of recently available cellular models for analysis of signaling pathways and gene expression, which complement behavioral neuroscience research in schizophrenia Edited and authored by leading researchers in the field of schizophrenia and related psychoses

The Neuropsychopathology of Schizophrenia

The Neuropsychopathology of Schizophrenia Book
Author : Ming Li,William D. Spaulding
Publisher : Springer
Release : 2016-05-30
ISBN : 3319305964
Language : En, Es, Fr & De

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Book Description :

One of the first major theoretical reviews of schizophrenia since the publication of the 5th edition of the APA’s Diagnostic and Statistical Manual, the DSM-5, this volume is a landmark in the history of schizophrenia research. It assembles recent groundbreaking developments in research on schizophrenia and reaffirms its central place in the mental health research agenda. Significantly, this volume reflects the paradigmatic shift in schizophrenia research applied in parallel to new approaches in psychiatric diagnosis. New models and findings from across disciplines in recent years reflect a new and greater understanding of the workings of the brain, which, in turn, helps develop our knowledge of the neuro and psychological processes in schizophrenia. Consequently, this volume illustrates a historical convergence of psychology, psychopathology and the neurosciences in schizophrenia. World-renowned leaders of the schizophrenia research community in fields such as neuroscience, p sychiatry, neuropsychology, and clinical psychology offer clear suggestions for further advances in psychological and medical interventions, assessment, prevention strategies, and research. And in keeping with other titles in the Nebraska Symposium on Motivation series, these papers are noteworthy for their depth of detail, scientific rigor, and clinical relevance. Included among the topics: Cognitive organization as a dimension of individual differences and psychopathology. Neurodevelopmental genomic strategies in the study of the psychosis spectrum. Multimodal brain and behavior indices of psychosis risk. The NIMH Research Domain Criteria Project: new approaches to classifying psychotic spectrum disorders. The Neuropsychopathology of Schizophrenia is one of the most forward-thinking and engaging treatments of the field in recent years, and is an i ndispensable text for all researchers, academics, and clinicians who treat or study mental illness, especially psychiatrists, psychologists, mental health practitioners, and neuroscientists specializing in schizophrenia.

The Neurobiology of Schizophrenia

The Neurobiology of Schizophrenia Book
Author : Ted Abel,Thomas Nickl-Jockschat
Publisher : Academic Press
Release : 2016-07-08
ISBN : 0128018771
Language : En, Es, Fr & De

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Book Description :

The Neurobiology of Schizophrenia begins with an overview of the various facets and levels of schizophrenia pathophysiology, ranging systematically from its genetic basis over changes in neurochemistry and electrophysiology to a systemic neural circuits level. When possible, the editors point out connections between the various systems. The editors also depict methods and research strategies used in the respective field. The individual backgrounds of the two editors promote a synthesis between basic neuroscience and clinical relevance. Provides a comprehensive overview of neurobiological aspects of schizophrenia Discusses schizophrenia at behavioral, cognitive, clinical, electrophysiological, molecular, and genetic levels Edited by a translational researcher and a psychiatrist to promote synthesis between basic neuroscience and clinical relevance Elucidates connections between the various systems depicted, when possible

Schizophrenia Second Edition

Schizophrenia  Second Edition Book
Author : Siegfried Kasper,George N. Papadimitriou
Publisher : CRC Press
Release : 2009-09-30
ISBN : 1420080067
Language : En, Es, Fr & De

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Book Description :

Edited by the president of the World Federation of Societies of Biological Psychiatry and featuring an international list of world-renown contributors, Schizophrenia, Second Edition provides psychiatrists, neurologists, and psychologists with a comprehensive handbook on the latest schizophrenia research and management from diagnosis through treatment. New features in this user-friendly Second Edition: Two-thirds new content, including 20 chapter additions detailed coverage of interviewing, symptomatology evaluation, and cognitive assessment strategies to ensure accurate differential diagnosis An in-depth discussion of both pharmacological and nonpharmacological treatment options A section on the neurobiology of schizophrenia, covering the latest in genetic and epigenetic factors, brain abnormalities, neuroimaging, biochemical alterations, and social cognition Treatment options for management of the disease, including treatment of the first schizophrenic episode, pharmacogenetic approaches, comparative efficacy of older vs. new antipsychotic medication, managing side-effects, psychosocial and cognitive rehabilitation, psychotherapy, and rehabilitation strategies

Psychopathology and personality dimensions

Psychopathology and personality dimensions Book
Author : Gordon Claridge
Publisher : Routledge
Release : 2018-05-15
ISBN : 1351975390
Language : En, Es, Fr & De

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Book Description :

In the World Library of Psychologists series, international experts present career-long collections of what they judge to be their finest pieces – extracts from books, key articles, salient research findings, and their major practical theoretical contributions. In this fascinating collection, Professor Gordon Claridge charts the development of a model of mental health that blurs the line between madness and sanity, conditions such as schizophrenia and other forms of psychosis seen as dimensions of ‘normal’ personality and temperament rather than separate abnormalities. Working with, and influenced by, the late Hans Eysenck, Claridge is celebrated for evolving research on personality and psychological disorders into a revised view of the spectrum of psychotic traits. The concept of schizotypy, re-evaluated by Claridge, sees mental illness not as a pathology suffered by a few, but as the end of a continuum experienced by us all. Psychopathology and Personality Dimensions brings together some of the author’s most influential publications on the topics of schizotypy and psychoticism, personality disorders, and the use of drug techniques to investigate normal and abnormal individual differences. Interspersed throughout with specially-written retrospectives by Professor Claridge, looking back at his work and contextualising where it sits in the wider literature, the collection illustrates a radical and influential model of mental illness that continues to resonate today. This book is an essential resource for all those engaged or interested in the field of personality and psychological disorders.

Real World Psychology

Real World Psychology Book
Author : Catherine A. Sanderson,Karen Huffman
Publisher : John Wiley & Sons
Release : 2019-12-24
ISBN : 1119577756
Language : En, Es, Fr & De

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Book Description :

Real World Psychology balances comprehensive coverage of the key concepts in introductory psychology with a concise presentation style and engages students with current and interesting research that explores these concepts in real-life contexts. Real World Psychology features the incomparable author team of Karen Huffman (Palomar College) and Catherine Sanderson (Amherst College) who create an outstanding text that is appealing to students and instructors at a wide range of academic institutions. The new edition has been thoroughly updated and features a new focus on Scientific Thinking and Practical Applications underscoring the fact that connecting the principles of psychological science to everyday life is critical to student engagement, and ultimately key to their success – not only in the introductory psychology course, but in whatever their chosen field of study and in everyday life. Students will leave the course with an appreciation of how a basic, yet scientific understanding of human behavior can benefit them in their studies, in their personal lives, and in their professional endeavors.

Schizophrenia Bulletin

Schizophrenia Bulletin Book
Author : Anonim
Publisher : Unknown
Release : 2006-04
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Schizophrenia Bulletin book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Schizophrenia Bulletin

Schizophrenia Bulletin Book
Author : Anonim
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Schizophrenia Bulletin book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Psychopathology in Epilepsy

Psychopathology in Epilepsy Book
Author : Steven Whitman,Bruce P. Hermann
Publisher : Oxford University Press, USA
Release : 1986
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

While mental illness in epileptics has been studied extensively from a biological perspective, little serious attention has been paid to the role of nonbiological factors. This well-balanced volume, written by an international group of researchers and epileptologists, is the first to bring together recent, and in some cases, previously unpublished research on the social precursors of psychopathology in epilepsy. Proposing a multietiologic model which includes biological and social factors, this comprehensive collection considers such high-risk social variables for psychopathology as fear of seizure, stigma, discrimination, and the control of medical information by doctors. These thirteen chapters provide a foundation for continuing research and eventually for improved care for people with epilepsy.

Oxford Textbook of Psychopathology

Oxford Textbook of Psychopathology Book
Author : Paul H. Blaney,Robert F. Krueger,Theodore Millon
Publisher : Oxford University Press, USA
Release : 2014-09-19
ISBN : 0199811776
Language : En, Es, Fr & De

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Book Description :

While most abnormal psychology texts seem to aim solely for breadth, the acclaimed Oxford Textbook of Psychopathology aims for depth, with a focus on adult disorders and special attention given to the personality disorders. Now in its third edition, it has established itself as an unparalleled guide for professionals and graduate students alike. Esteemed editors Paul H. Blaney, Robert F. Krueger, and the late Theodore Millon selected the most eminent researchers in abnormal psychology to cover all the major mental disorders, allowing them to discuss notable issues in the various pathologies which are their expertise. This third edition of the Oxford Textbook of Psychopathology is fully updated according to the DSM-5 and also reflects alternative, emerging perspectives in the field (e.g., the NIMH's Research Domain Criteria Initiative; RDoC). The Textbook exposes readers to exceptional scholarship, a history of psychopathology, the logic of the best approaches to current disorders, and an expert outlook on what researchers and mental health professionals will be facing in the years to come. With extensive coverage of personality disorders and issues related to classification and differential diagnosis, this volume will be exceptionally useful for all mental health workers, clinical psychologists, psychiatrists, and social workers, and as a textbook focused on understanding psychopathology in depth, as well as a valuable guide for graduate psychology students and psychiatric residents.

Translational Neuropsychopharmacology

Translational Neuropsychopharmacology Book
Author : Trevor W. Robbins,Barbara J. Sahakian
Publisher : Springer
Release : 2016-09-22
ISBN : 3319339133
Language : En, Es, Fr & De

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Book Description :

This book covers wide areas of animal and human psychopharmacology with clinical utility in the treatment of psychiatric and neurological (e.g Alzheimer's disease) disorders. The main theme is to develop a new paradigm for drug discovery that questions the claim that animal models or assays fail adequately to predict Phase 3 clinical trials. A new paradigm is advocated that stresses the importance of intermediate staging points between these extremes that depend on suitable translation of findings from animal studies to Phase 1 or Phase 2 studies utilising experimental medicine.

Therapy Resistant Schizophrenia

Therapy Resistant Schizophrenia Book
Author : H. Elkis,H.Y. Meltzer
Publisher : Karger Medical and Scientific Publishers
Release : 2010-07-29
ISBN : 3805595123
Language : En, Es, Fr & De

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Book Description :

The psychotic symptoms of up to 30% of schizophrenic patients do not respond adequately to treatment with antipsychotic drugs, other than clozapine. These refractory patients are generally among the most disabled of all people with schizophrenia and require special assessment and treatment. This volume presents the latest research and recommendations on the definition, causes and therapy of treatment-resistant schizophrenia (TRS). Methods for identification and optimal management of TRS are reviewed. Clozapine and other atypical antipsychotic drugs which are the primary treatment for TRS, as well as non-pharmacologic treatments such as transcranial magnetic stimulation, cognitive behavior therapy and ECT are discussed in depth. Potential causative factors and identifying features such as genetic factors, poor premorbid functioning, longer duration of untreated psychosis, and biological measures such as structural and functional brain abnormalities are also reviewed in depth in the present volume.

The Oxford Handbook of Stress and Mental Health

The Oxford Handbook of Stress and Mental Health Book
Author : Kate L. Harkness,Elizabeth P. Hayden
Publisher : Oxford University Press, USA
Release : 2020
ISBN : 0190681772
Language : En, Es, Fr & De

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Book Description :

This handbook is currently in development, with individual articles publishing online in advance of print publication. At this time, we cannot add information about unpublished articles in this handbook, however the table of contents will continue to grow as additional articles pass through the review process and are added to the site. Please note that the online publication date for this handbook is the date that the first article in the title was published online.

Women Mental Illness Drugs and Crime

Women  Mental Illness  Drugs  and Crime Book
Author : Alison C. Smith (George Mason University graduate)
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Women Mental Illness Drugs and Crime book written by Alison C. Smith (George Mason University graduate), available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The DSM 5 Alternative Model for Personality Disorders

The DSM 5 Alternative Model for Personality Disorders Book
Author : Christopher J. Hopwood,Abby L Mulay,Mark H Waugh
Publisher : Routledge
Release : 2019-01-15
ISBN : 135179292X
Language : En, Es, Fr & De

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Book Description :

The DSM-5 Alternative Model for Personality Disorders reviews and advances this innovative and increasingly popular scheme for diagnosing and evaluating personality disorders. The authors identify the multiple clinical, theoretical, and research paradigms that co-exist in the Alternative Model for Personality Disorders (AMPD) and show how the model can aid the practicing mental health professional in evaluating and treating patients as well as its importance in stimulating research and theoretical understanding of this domain. This work explores and summarizes methods of personality assessment and psychiatric evaluation, research findings, and clinical applications of the AMPD, highlighting its usefulness to clinical teaching and supervision, forensic application, and current research. It is a go-to reference for experienced professionals and researchers, those who wish to learn this new diagnostic system, and for clinicians in training.

Contemporary Issues in Modeling Psychopathology

Contemporary Issues in Modeling Psychopathology Book
Author : Michael S. Myslobodsky,Ina Weiner
Publisher : Springer Science & Business Media
Release : 2000-12-31
ISBN : 9780792379423
Language : En, Es, Fr & De

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Book Description :

Despite considerable progress in clinical and basic neurosciences, the cure of psychiatric disorders is still remote, little is known about their prevention, and the etiology and molecular mechanisms of mental disorders are still obscure. Diagnoses are still guided by patients' stories. The mission of animal models is to bridge the gap between `the story and the synapse.' Contemporary Issues in Modeling of Psychopathology attempts to do this by examining such questions as `What good might come from such a model? Are we wasting our time? How far can we carry results from model animals, such as rats and mice, without causing a highly distorted view of the field and its goals?' This book serves as the opening volume for a new series, Neurobiological Foundation of Aberrant Behaviors.

Psychopathology

Psychopathology Book
Author : Louis G. Castonguay,Thomas F. Oltmanns
Publisher : Guilford Publications
Release : 2013-08-26
ISBN : 146250809X
Language : En, Es, Fr & De

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Book Description :

This book has been replaced by Psychopathology, Second Edition, ISBN 978-1-4625-4761-6.

Entropy of Mind and Negative Entropy

Entropy of Mind and Negative Entropy Book
Author : Tullio Scrimali
Publisher : Routledge
Release : 2018-05-08
ISBN : 0429913303
Language : En, Es, Fr & De

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Book Description :

Schizophrenia is the central problem in the sciences of the mind, not only for its etiological, psychopathological and clinical aspects, but also because of its implications for therapy and rehabilitation. In this volume the author describes a series of new scientific and clinical perspectives for schizophrenia influenced by cognitivist and constructivist approaches and informed by the logic of complexity and non-linear, dynamic systems. The author delineates a new complex theory of the brain and a procedural theory of the mind, founded on the concept of the modular brain and the coalitional mind. Subsequently, the author develops a multi-factorial conceptualization of the etiological dynamic and an original, complex, and evolutionary perspective concerning the psychotic condition, which has been redefined, in this case, as Entropy of the Mind or Phrenentropy. In conclusion, the author illustrates an innovative, integrated protocol, denominated Negative Entropy, for the treatment and rehabilitation of patients with schizophrenia.

Novel Antischizophrenia Treatments

Novel Antischizophrenia Treatments Book
Author : Mark A. Geyer,Gerhard Gross
Publisher : Springer Science & Business Media
Release : 2012-08-31
ISBN : 3642257577
Language : En, Es, Fr & De

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Book Description :

This volume will try to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters will also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. The volume will concentrate on reviewing the ongoing research attempting to identify novel treatments for the cognitive deficits and negative symptoms of schizophrenia, which are not treated adequately by current antipsychotic medications.