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Microfluidics For Cellular Applications

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Microfluidics for Cellular Applications

Microfluidics for Cellular Applications Book
Author : Gerardo Perozziello,Ulrich Kruhne,Paola Luciani
Publisher : Elsevier
Release : 2021-07-15
ISBN : 9780128224823
Language : En, Es, Fr & De

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Book Description :

Microfluidics for Cellular Applications describes microfluidic devices for cell screening from a physical, technological and applications point of view, giving a comparison with the cell microenvironment and the conventional instruments used in medicine. Microfluidic technologies, protocols, devices for cell screening and treatment have reached an advanced state, but, still, they are mainly used in research and for research purposes. They have not broken into practical applications and conventional medical procedures due to the fact that, most of the time, they are cumbersome to use, unreliable or require complicated or expensive set-ups to be handled. On the other hand, microfluidic devices can offer unique insights and analysis and can reach higher resolutions and fast operations in comparison to conventional medical and biotechnologies. This is an important resource for those from an engineering and technology background to understand more about the microfluidic methods that can be used to gain additional insights into cell screening processes. Outlines the major applications of microfluidic devices in medicine and biotechnology Assesses the major challenges of using microfluidic devices in terms of complexity of the control set-up, ease of use, integration capability, automation level, analysis throughput, content and costs Describes the major fabrication techniques for assembling effective microfluidic devices for bioapplications

Microfluidic Devices for Biomedical Applications

Microfluidic Devices for Biomedical Applications Book
Author : Xiujun James Li,Yu Zhou
Publisher : Elsevier
Release : 2013-10-31
ISBN : 0857097040
Language : En, Es, Fr & De

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Book Description :

Microfluidics or lab-on-a-chip (LOC) is an important technology suitable for numerous applications from drug delivery to tissue engineering. Microfluidic devices for biomedical applications discusses the fundamentals of microfluidics and explores in detail a wide range of medical applications. The first part of the book reviews the fundamentals of microfluidic technologies for biomedical applications with chapters focussing on the materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies. Chapters in part two examine applications in drug discovery and controlled-delivery including micro needles. Part three considers applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds and stem cell engineering. The final part of the book covers the applications of microfluidic devices in diagnostic sensing, including genetic analysis, low-cost bioassays, viral detection, and radio chemical synthesis. Microfluidic devices for biomedical applications is an essential reference for medical device manufacturers, scientists and researchers concerned with microfluidics in the field of biomedical applications and life-science industries. Discusses the fundamentals of microfluidics or lab-on-a-chip (LOC) and explores in detail a wide range of medical applications Considers materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies Considers applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds and stem cell engineering

Microfluidics in Cell Biology Part C Microfluidics for Cellular and Subcellular Analysis

Microfluidics in Cell Biology Part C  Microfluidics for Cellular and Subcellular Analysis Book
Author : Anonim
Publisher : Academic Press
Release : 2018-11-22
ISBN : 0128142855
Language : En, Es, Fr & De

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Book Description :

Microfluidics in Cell Biology Part C, Volume 148, a new release in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are three sections on microfluidics in various multi-cellular models, including microfluidics in cell monolayers/spheroids, microfluidics in organ on chips, and microfluidics in model organisms. Specific chapters discuss collective migration in microtubes, leukocyte adhesion dynamics on endothelial monolayers under flow, constrained spheroid for perfusion culture, cells in droplet arrays, heart on chips, kidney on chips, liver on chips, and more. Contains contributions from experts in the field from across the world Covers a wide array of topics on both mitosis and meiosis Includes relevant, analysis based topics

Microfluidics for Cellular Engineering

Microfluidics for Cellular Engineering Book
Author : Jean Berthier
Publisher : William Andrew
Release : 2025-08-01
ISBN : 9781437734584
Language : En, Es, Fr & De

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Book Description :

The focus of biotechnology has progressively shifted from DNA recognition to protein analysis and, more recently, to the study of cells. It is expected that major advances in pharmacology and in-vivo medicine will stem from the in-depth understanding of cellular mechanisms. Microfluidic systems have become established as the preferred tools for the investigation of cellular mechanisms. They provide a unique ability to use only minor quantities of expensive biochemical reactants, to provide an utmost controlled environment, and to allow for specific and sensitive observations of the cells and subsequent manipulation for device functionality. However, achieving such goals requires a sophisticated and specific microfluidic approach in order to manipulate cells and/or clusters of cells. In this handbook, the authors explore the key topics around the use of microfluidics in the exploration of cellular mechanisms: The different techniques used to transport, manipulate, separate and encapsulate cells or clusters of cells. The problem of cellular culture Tissue engineering Analysis of cell response to biochemical gradients and self-motion of cells in a microfluidic environment Imaging methods to follow cellular behaviourC Cell-to-cell communication, from a physical point of view (cellular mechanics) and a chemical point of view (biochemical signals) The aim of this book is to provide the reader with a solid, up-to-date working knowledge of microfluidic systems for cellular investigations and device development. Examples of applications are systematically presented, and the text is written with the desire to present the fundamentals of each one of the preeminent topics for today’s engineering-based research of cellular mechanisms. The book will provide a guide to techniques and applications for professionals in the fields of bioengineering, biomedical research and medical laboratory technologies An integrated approach to the fundamentals of cellular mechanics, cellular communications and cellular microfluidics: transport, manipulation, separation, trapping, etc. Detailed explanation of the design and analysis uses of new cellular microsystems, e,g, point-of-care systems for blood analysis and microsystems for stem cells / cancer cells Provides a practically-oriented understanding of cell-based sampling and screening mechanisms and technologies Guidance on the manipulation, modeling and measurement of cells in the context of new drug development and testing

Microfluidic Chip Applications in Cellular Studies

Microfluidic Chip Applications in Cellular Studies Book
Author : Hsing-Yun Sharon Hsu
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Microfluidic Chip Applications in Cellular Studies book written by Hsing-Yun Sharon Hsu, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Microfluidics for Quantitative Analysis of Cellular and Intercellular Interactions

Microfluidics for Quantitative Analysis of Cellular and Intercellular Interactions Book
Author : Timothy Kwa
Publisher : Unknown
Release : 2016
ISBN : 9781339825427
Language : En, Es, Fr & De

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Book Description :

The field of microfluidics has grown steadily over the last decade and a half, due in part to the large variety of applications for manipulating fluids in nanoliter volumes. Specifically for biomedical engineering, microfluidics has been employed for creating small, well-controlled microenvironments for reliable analysis of small populations of cells. Thus, a thoughtfully designed microfluidic device can be extremely powerful toward assaying various cell functions, including the analysis of the cellular secretome. The focus of this thesis involves creating precisely engineered microfluidic devices to analyze small cell populations contained within carefully considered geometries. By integrating biosensors (electrochemical and optical) with these cellular microenvironments, we can achieve near real-time quantitative analysis of cell-secreted products in response to external stimuli. Combined with computational modeling techniques, we can calculate secretion rates for these products. Moreover, these microenvironments can also serve protective functions and toggle cellular communication, yielding novel information and insights into cellular responses. Through series of experiments such as these, we can develop novel methods for addressing and manipulating cell performance, especially in the context of disease or cellular dysfunction. My work involved microfluidic device design, prototyping, fabrication, and testing to obtain meaningful, quantitative results based on cellular function. Chapter 2 describes a microfluidic device capable of detecting two pro-inflammatory cytokines from cells. In Chapter 3, a reconfigurable microfluidic device was designed to protect cells while regenerating a sensor surface. Chapter 4 describes a microfluidic co-culture of liver cells, monitoring the paracrine interactions between hepatocytes and stellate cells. Chapter 5 reports on the detection of cell-secreted cytokines, analyzed in a reconfigurable device facilitating intercellular communication. In chapter 6, a microfluidic device with integrated valves was designed to assay cellular response to a predictably evolving chemical gradient. These devices with their disparate applications have produced a variety of interesting results pertaining to cellular function and intercellular communication. To this end, future work may be useful for shedding insights into disease pathogenesis and treatment, especially in terms of quantifying dose-dependent responses.

Biological Applications of Microfluidics

Biological Applications of Microfluidics Book
Author : Frank A. Gomez
Publisher : John Wiley & Sons
Release : 2008-02-15
ISBN : 0470074833
Language : En, Es, Fr & De

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Book Description :

Microfluidics-today's applications and tomorrow's potential Microfluidics has facilitated major biochemical application advancements in point-of-care diagnostics, bioterrorism detection, and drug discovery. There are numerous potential applications in biotechnology, pharmaceuticals, the life sciences, defense, public health, and agriculture. Microfluidic lab-on-a-chip (LOC) technologies represent a revolution in laboratory experimentation, bringing the benefits of miniaturization, integration, and automation to many research-based industries. Biological Applications of Microfluidics details recent advances in the biological applications of microfluidics, including cell sorting, DNA sequencing on a chip, microchip capillary electrophoresis, and synthesis on a microfluidic format. After an overview of microfluidics highlighting recent seminal works, it includes multiple chapters on: * Cell analysis on microfluidic devices * Chemical (enzymatic and non-enzymatic) reactions on microchips * Separations on microchips * Biomedical applications of microfluidics * Microfluidic fabrication * Hybrid microfluidic applications Microfluidics has incredible potential in a variety of areas. This book covers many recent advances, including microfabricated LOC technologies, advanced microfluidic tools, microfluidic culture platforms for stem cell and neuroscience research, a novel application of microfluidic LOC devices that facilitates fundamental research in proteomics that cannot be performed without miniaturization, the nano fountain pen, and more. With contributions from leading experts in chemistry, physics, bioengineering, material science, biomedicine, and other fields plus references at the end of each chapter to facilitate further study, this is an all-in-one, hands-on resource for analytical chemists and researchers. It is also an excellent resource for students studying analytical chemistry or biotechnology.

Microfluidics for Biological Applications

Microfluidics for Biological Applications Book
Author : Wei-Cheng Tian,Erin Finehout
Publisher : Springer Science & Business Media
Release : 2009-03-02
ISBN : 0387094806
Language : En, Es, Fr & De

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Book Description :

Microfluidics for Biological Applications provides researchers and scientists in the biotechnology, pharmaceutical, and life science industries with an introduction to the basics of microfluidics and also discusses how to link these technologies to various biological applications at the industrial and academic level. Readers will gain insight into a wide variety of biological applications for microfluidics. The material presented here is divided into four parts, Part I gives perspective on the history and development of microfluidic technologies, Part II presents overviews on how microfluidic systems have been used to study and manipulate specific classes of components, Part III focuses on specific biological applications of microfluidics: biodefense, diagnostics, high throughput screening, and tissue engineering and finally Part IV concludes with a discussion of emerging trends in the microfluidics field and the current challenges to the growth and continuing success of the field.

Applications of Microfluidic Systems in Biology and Medicine

Applications of Microfluidic Systems in Biology and Medicine Book
Author : Manabu Tokeshi
Publisher : Springer
Release : 2019-04-25
ISBN : 9811362297
Language : En, Es, Fr & De

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Book Description :

This book focuses on state-of-the-art microfluidic research in medical and biological applications. The top-level researchers in this research field explain carefully and clearly what can be done by using microfluidic devices. Beginners in the field —undergraduates, engineers, biologists, medical researchers—will easily learn to understand microfluidic-based medical and biological applications. Because a wide range of topics is summarized here, it also helps experts to learn more about fields outside their own specialties. The book covers many interesting subjects, including cell separation, protein crystallization, single-cell analysis, cell diagnosis, point-of-care testing, immunoassay, embyos/worms on a chip and organ-on-a-chip. Readers will be convinced that microfluidic devices have great potential for medical and biological applications.

Microfluidics for Biological Applications

Microfluidics for Biological Applications Book
Author : Wei-Cheng Tian,Erin Finehout
Publisher : Springer
Release : 2010-10-12
ISBN : 9781441934840
Language : En, Es, Fr & De

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Book Description :

Microfluidics for Biological Applications provides researchers and scientists in the biotechnology, pharmaceutical, and life science industries with an introduction to the basics of microfluidics and also discusses how to link these technologies to various biological applications at the industrial and academic level. Readers will gain insight into a wide variety of biological applications for microfluidics. The material presented here is divided into four parts, Part I gives perspective on the history and development of microfluidic technologies, Part II presents overviews on how microfluidic systems have been used to study and manipulate specific classes of components, Part III focuses on specific biological applications of microfluidics: biodefense, diagnostics, high throughput screening, and tissue engineering and finally Part IV concludes with a discussion of emerging trends in the microfluidics field and the current challenges to the growth and continuing success of the field.

Microfluidics in Cell BiologyPart A Microfluidics for multicellular systems

Microfluidics in Cell BiologyPart A  Microfluidics for multicellular systems Book
Author : Anonim
Publisher : Academic Press
Release : 2018-07-20
ISBN : 0128142812
Language : En, Es, Fr & De

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Book Description :

Microfluidics in Cell Biology Part A: Volume 146, the latest release in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are sections on Cell monolayers/spheroids, Collective migration in microtubes, Leukocyte adhesion dynamics on endothelial monolayers under flow, Constrained spheroid for perfusion culture, Cells in droplet arrays, Heart on chips, Kidney on chips, Liver on chips and hepatic immune responses, Gut on chips, 3D microvascular model-based lymphoma model, Blood brain barrier on chips, Multi-organ-on-a-chip for pharmacokinetic analysis, Cancer immunotherapy on chips, and more. Contains contributions from experts in the field from across the globe Covers a wide array of topics on both mitosis and meiosis Includes relevant, analysis based topics

Pulsed Laser Microbeams for Cellular Manipulation

Pulsed Laser Microbeams for Cellular Manipulation Book
Author : Amy Noel Stacy Hellman
Publisher : ProQuest
Release : 2008
ISBN : 9780549605348
Language : En, Es, Fr & De

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Book Description :

Highly focused pulsed laser radiation (pulsed laser microbeams) provide the ability to deposit energy with high spatial precision and controllable cellular damage. As a result, pulsed laser microbeams have been explored as a fast, non-contact means for cellular manipulations such as cellular microsurgery, transient cell membrane permeabilization, and targeted cell lysis. In this dissertation we examine the mechanisms of highly focused laser microbeams of nanosecond and picosecond duration to achieve cell lysis, cell necrosis, and molecular delivery. We have developed a time-resolved imaging system to visualize these processes with nanosecond temporal resolution and use image analysis to measure the physical perturbation applied to the cells as a function of laser microbeam pulse energy and pulse duration. Fluorescence assays are used to assess the biological response (necrosis, molecular delivery, and biochemical pathway activity) to the laser microbeam irradiation, and a biophysical model is developed to establish connections between specific physical characteristics and the resulting cellular effect. Our studies reveal that pulsed laser microbeam processes are mediated by optical breakdown resulting in plasma formation, shock wave emission, and cavitation bubble formation, expansion, and collapse. Cavitation bubble expansion was found to be the primary mechanism responsible for cellular modification. Hydrodynamic analysis based on the measured time evolution of the cavitation bubble growth, combined with assessment of the cellular response, revealed that the maximum wall shear stress associated with the cavitation bubble expansion governs the location and spatial extent of cell lysis, cell necrosis, and molecular delivery. In addition, we demonstrate how the variation of laser microbeam pulse duration can allow modulation of the spatial extent of cellular modification in order to tailor the cellular perturbations and optimize specific applications. These detailed studies provide a basis for the informed selection of specific laser parameters (i.e. pulse duration and energy) to achieve a desired cellular outcome, with controllable degrees of collateral damage. We demonstrate three different applications in which the laser parameters are well matched for particular applications in cellular analytics, activation of biochemical pathways, and microfluidics.

Cell Analysis on Microfluidics

Cell Analysis on Microfluidics Book
Author : Jin-Ming Lin
Publisher : Springer
Release : 2017-10-25
ISBN : 9811053944
Language : En, Es, Fr & De

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Book Description :

This book presents a detailed overview of the design, formatting, application, and development of microfluidic chips in the context of cell biology research, enumerating each element involved in microfluidics-based cell analysis, discussing its history, status quo, and future prospects, It also offers an extensive review of the research completed in the past decade, including numerous color figures. The individual chapters are based on the respective authors' studies and experiences, providing tips from the frontline to help researchers overcome bottlenecks in their own work. It highlights a number of cutting-edge techniques, such as 3D cell culture, microfluidic droplet technique, and microfluidic chip-mass spectrometry interfaces, offering a first-hand impression of the latest trends in the field and suggesting new research directions. Serving as both an elementary introduction and advanced guidebook, the book interests and inspires scholars and students who are currently studying microfluidics-based cell analysis methods as well as those who wish to do so.

Fundamentals and Applications of Microfluidics Third Edition

Fundamentals and Applications of Microfluidics  Third Edition Book
Author : Nam-Trung Nguyen,Steven T. Wereley,Seyed Ali Mousavi Shaegh
Publisher : Artech House
Release : 2019-01-31
ISBN : 1630813656
Language : En, Es, Fr & De

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Book Description :

Now in its Third Edition, the Artech House bestseller, Fundamentals and Applications of Microfluidics, provides engineers and students with the most complete and current coverage of this cutting-edge field. This revised and expanded edition provides updated discussions throughout and features critical new material on microfluidic power sources, sensors, cell separation, organ-on-chip and drug delivery systems, 3D culture devices, droplet-based chemical synthesis, paper-based microfluidics for point-of-care, ion concentration polarization, micro-optofluidics and micro-magnetofluidics. The book shows how to take advantage of the performance benefits of microfluidics and serves as an instant reference for state-of-the-art microfluidics technology and applications. Readers find discussions on a wide range of applications, including fluid control devices, gas and fluid measurement devices, medical testing equipment, and implantable drug pumps. Professionals get practical guidance in choosing the best fabrication and enabling technology for a specific microfluidic application, and learn how to design a microfluidic device. Moreover, engineers get simple calculations, ready-to-use data tables, and rules of thumb that help them make design decisions and determine device characteristics quickly.

Open Space Microfluidics

Open Space Microfluidics Book
Author : Emmanuel Delamarche,Govind V. Kaigala
Publisher : John Wiley & Sons
Release : 2018-01-18
ISBN : 3527696806
Language : En, Es, Fr & De

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Book Description :

Summarizing the latest trends and the current state of this research field, this up-to-date book discusses in detail techniques to perform localized alterations on surfaces with great flexibility, including microfluidic probes, multifunctional nanopipettes and various surface patterning techniques, such as dip pen nanolithography. These techniques are also put in perspective in terms of applications and how they can be transformative of numerous (bio)chemical processes involving surfaces. The editors are from IBM Zurich, the pioneers and pacesetters in the field at the forefront of research in this new and rapidly expanding area.

Multidisciplinary Microfluidic and Nanofluidic Lab on a Chip

Multidisciplinary Microfluidic and Nanofluidic Lab on a Chip Book
Author : Xiujun James Li,Merwan Benhabib,Paul Li
Publisher : Newnes
Release : 2020-01-01
ISBN : 9780444594617
Language : En, Es, Fr & De

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Book Description :

Recent advances in microfluidics and Microsystems for life sciences are impacting chemistry, biophysics, molecular and cell biology, and medicine for applications that include DNA analysis, drug discovery, disease research, and biofluid and environmental monitoring. This title serves as a reference for technologies and applications in multidisciplinary areas, with an emphasis placed on quickly developing or new emerging areas to include digital microfluidics, nanofluidics, papers-based microfluidics, and cell biology. It will offer practical guidance on how to design, analyze, fabricate and test microfluidic devices and systems for a wide variety of applications including separations, disease detection, cellular analysis, DNA analysis, proteomics and drug delivery. Calculations, solved problems, data table and design rules are provide to help researchers understand microfluidic basic theory and principles, as well as apply this knowledge to their own unique designs. This book provides chemists, biophysicists, engineers, life scientists, and members of the biotechnology and pharmaceutical sector with an applied understanding of the principles behind the design, manufacture, and testing of life sciences microfluidic systems. Provides calculations, solved problems, data tables and design rules to help to understand microfluidic basic theory and principles Gives an applied understanding of the principles behind the design, manufacture and testing of microfluidic systems Emphasizes on quickly developing and emerging areas including digital microfluidics, nanofluidics, papers-based microfluidics and cell biology

Biomedical Applications of Microfluidic Devices

Biomedical Applications of Microfluidic Devices Book
Author : Michael R. Hamblin,Mahdi Karimi
Publisher : Academic Press
Release : 2020-11-12
ISBN : 0128187921
Language : En, Es, Fr & De

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Book Description :

Biomedical Applications of Microfluidic Devices introduces the subject of microfluidics and covers the basic principles of design and synthesis of actual microchannels. The book then explores how the devices are coupled to signal read-outs and calibrated, including applications of microfluidics in areas such as tissue engineering, organ-on-a-chip devices, pathogen identification, and drug/gene delivery. This book covers high-impact fields (microarrays, organ-on-a-chip, pathogen detection, cancer research, drug delivery systems, gene delivery, and tissue engineering) and shows how microfluidics is playing a key role in these areas, which are big drivers in biomedical engineering research. This book addresses the fundamental concepts and fabrication methods of microfluidic systems for those who want to start working in the area or who want to learn about the latest advances being made. The subjects covered are also an asset to companies working in this field that need to understand the current state-of-the-art. The book is ideal for courses on microfluidics, biosensors, drug targeting, and BioMEMs, and as a reference for PhD students. The book covers the emerging and most promising areas of biomedical applications of microfluidic devices in a single place and offers a vision of the future. Covers basic principles and design of microfluidics devices Explores biomedical applications to areas such as tissue engineering, organ-on-a-chip, pathogen identification, and drug and gene delivery Includes chemical applications in organic and inorganic chemistry Serves as an ideal text for courses on microfluidics, biosensors, drug targeting, and BioMEMs, as well as a reference for PhD students

Microfluidics and Bio MEMS

Microfluidics and Bio MEMS Book
Author : Tuhin S. Santra
Publisher : CRC Press
Release : 2020-11-01
ISBN : 1000769135
Language : En, Es, Fr & De

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Book Description :

The past two decades have seen rapid development of micro-/nanotechnologies with the integration of chemical engineering, biomedical engineering, chemistry, and life sciences to form bio-MEMS or lab-on-chip devices that help us perform cellular analysis in a complex micro-/nanoflluidic environment with minimum sample consumption and have potential biomedical applications. To date, few books have been published in this field, and researchers are unable to find specialized content. This book compiles cutting-edge research on cell manipulation, separation, and analysis using microfluidics and bio-MEMS devices. It illustrates the use of micro-robots for biomedical applications, vascularized microfluidic organs-on-a-chip and their applications, as well as DNA gene microarray biochips and their applications. In addition, it elaborates on neuronal cell activity in microfluidic compartments, microvasculature and microarray gene patterning, different physical methods for drug delivery and analysis, micro-/nanoparticle preparation and separation in a micro-/nanofluidic environment, and the potential biomedical applications of micro-/nanoparticles. This book can be used by academic researchers, especially those involved in biomicrofluidics and bio-MEMS, and undergraduate- and graduate-level students of bio-MEMS/bio-nanoelectromechanical systems (bio-NEMS), biomicrofluidics, biomicrofabricatios, micro-/nanofluidics, biophysics, single-cell analysis, bionanotechnology, drug delivery systems, and biomedical micro-/nanodevices. Readers can gain knowledge of different aspects of microfluidics and bio-MEMS devices; their design, fabrication, and integration; and biomedical applications. The book will also help biotechnology-based industries, where research and development is ongoing in cell-based analysis, diagnosis, and drug screening.

Encyclopedia of Spectroscopy and Spectrometry

Encyclopedia of Spectroscopy and Spectrometry Book
Author : Anonim
Publisher : Academic Press
Release : 2016-09-22
ISBN : 0128032251
Language : En, Es, Fr & De

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Book Description :

This third edition of the Encyclopedia of Spectroscopy and Spectrometry provides authoritative and comprehensive coverage of all aspects of spectroscopy and closely related subjects that use the same fundamental principles, including mass spectrometry, imaging techniques and applications. It includes the history, theoretical background, details of instrumentation and technology, and current applications of the key areas of spectroscopy. The new edition will include over 80 new articles across the field. These will complement those from the previous edition, which have been brought up-to-date to reflect the latest trends in the field. Coverage in the third edition includes: Atomic spectroscopy Electronic spectroscopy Fundamentals in spectroscopy High-Energy spectroscopy Magnetic resonance Mass spectrometry Spatially-resolved spectroscopic analysis Vibrational, rotational and Raman spectroscopies The new edition is aimed at professional scientists seeking to familiarize themselves with particular topics quickly and easily. This major reference work continues to be clear and accessible and focus on the fundamental principles, techniques and applications of spectroscopy and spectrometry. Incorporates more than 150 color figures, 5,000 references, and 300 articles for a thorough examination of the field Highlights new research and promotes innovation in applied areas ranging from food science and forensics to biomedicine and health Presents a one-stop resource for quick access to answers and an in-depth examination of topics in the spectroscopy and spectrometry arenas