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Microbial Cell Factories Engineering For Production Of Biomolecules

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Microbial Cell Factories Engineering for Production of Biomolecules

Microbial Cell Factories Engineering for Production of Biomolecules Book
Author : Vijai Singh
Publisher : Academic Press
Release : 2021-02-26
ISBN : 0128214783
Language : En, Es, Fr & De

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Book Description :

Microbial Cell Factories Engineering for Production of Biomolecules presents a compilation of chapters written by eminent scientists worldwide. Sections cover major tools and technologies for DNA synthesis, design of biosynthetic pathways, synthetic biology tools, biosensors, cell-free systems, computer-aided design, OMICS tools, CRISPR/Cas systems, and many more. Although it is not easy to find relevant information collated in a single volume, the book covers the production of a wide range of biomolecules from several MCFs, including Escherichia coli, Bacillus subtilis, Pseudomonas putida, Streptomyces, Corynebacterium, Cyanobacteria, Saccharomyces cerevisiae, Pichia pastoris and Yarrowia lipolytica, and algae, among many others. This will be an excellent platform from which scientific knowledge can grow and widen in MCF engineering research for the production of biomolecules. Needless to say, the book is a valuable source of information not only for researchers designing cell factories, but also for students, metabolic engineers, synthetic biologists, genome engineers, industrialists, stakeholders and policymakers interested in harnessing the potential of MCFs in several fields. Offers basic understanding and a clear picture of various MCFs Explains several tools and technologies, including DNA synthesis, synthetic biology tools, genome editing, biosensors, computer-aided design, and OMICS tools, among others Harnesses the potential of engineered MCFs to produce a wide range of biomolecules for industrial, therapeutic, pharmaceutical, nutraceutical and biotechnological applications Highlights the advances, challenges, and future opportunities in designing MCFs

Microbial Cell Factories

Microbial Cell Factories Book
Author : Deepansh Sharma,Baljeet Singh Saharan
Publisher : CRC Press
Release : 2018-03-22
ISBN : 1351668056
Language : En, Es, Fr & De

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Book Description :

Microbial Cell Factories is a conceptual, reference-based source including chapters covering microbial cell factories for industrial developments, microbial biotechnology, sustainable environmental solutions, agriculture practices, microorganisms in food processing, metabolites as next generation food additives/food processing, and microbial cell factories in alternative energy fuel generation. The book highlights trends and developments in the field of microbial products, written by an international team of leading academic and research scholars. Key Selling Features: Highlights trends and developments in microbial biotechnology Systematically reviews microbial cell factories Explores the potential of microbial cell derived industrial production Synthesizes information on environmental and agricultural uses of microbial biotechnology Contributions from an international team of leading scholars

Yeast Metabolic Engineering

Yeast Metabolic Engineering Book
Author : Valeria Mapelli
Publisher : Humana Press
Release : 2014-04-18
ISBN : 9781493905621
Language : En, Es, Fr & De

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Book Description :

Yeast Metabolic Engineering: Methods and Protocols provides the widely established basic tools used in yeast metabolic engineering, while describing in deeper detail novel and innovative methods that have valuable potential to improve metabolic engineering strategies in industrial biotechnology applications. Beginning with an extensive section on molecular tools and technology for yeast engineering, this detailed volume is not limited to methods for Saccharomyces cerevisiae, but describes tools and protocols for engineering other yeasts of biotechnological interest, such as Pichia pastoris, Hansenula polymorpha and Zygosaccharomyces bailii. Tools and technologies for the investigation and determination of yeast metabolic features are described in detail as well as metabolic models and their application for yeast metabolic engineering, while a chapter describing patenting and regulations with a special glance at yeast biotechnology closes the volume. Written in the highly successful Methods in Molecular Biology series format, most chapters include an introduction to their respective topic, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Comprehensive and authoritative, Yeast Metabolic Engineering: Methods and Protocols aims to familiarize researchers with the current state of these vital and increasingly useful technologies.

One Carbon Feedstocks for Sustainable Bioproduction

One Carbon Feedstocks for Sustainable Bioproduction Book
Author : An-Ping Zeng,Nico J. Claassens
Publisher : Springer Nature
Release : 2022-05-31
ISBN : 3031068548
Language : En, Es, Fr & De

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Book Description :

This book offers a comprehensive review of the latest developments, challenges and trends in C1-based (one-carbon based) bioproduction, and it presents an authoritative account of one-carbon compounds as promising alternative microbial feedstocks. The book starts with a perspective on the future of C1 compounds as alternative feedstocks for microbial growth, and their vital role in the establishment of a sustainable circular carbon economy, followed by several chapters in which expert contributors discuss about the recent strategies and address key challenges regarding one or more C1 feedstocks. The book covers topics such as acetogenic production from C1 feedstocks, aerobic carboxydotrophic bacteria potential in industrial biotechnology, bioconversion of methane to value-added compounds, combination of electrochemistry and biology to convert C1 compounds, and bioprocesses based on C1-mixotrophy. Particular attention is given to the current metabolic engineering, systems biology, and synthetic biology strategies applied in this field.

Microbial Cell Factories

Microbial Cell Factories Book
Author : Deepansh Sharma,Baljeet Singh Saharan
Publisher : CRC Press
Release : 2021-03-30
ISBN : 9780367657307
Language : En, Es, Fr & De

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Book Description :

Microbial Cell Factories is a conceptual, reference-based source including chapters covering microbial cell factories for industrial developments, microbial biotechnology, sustainable environmental solutions, agriculture practices, microorganisms in food processing, metabolites as next generation food additives/food processing, and microbial cell factories in alternative energy fuel generation. The book highlights trends and developments in the field of microbial products, written by an international team of leading academic and research scholars. Key Selling Features: Highlights trends and developments in microbial biotechnology Systematically reviews microbial cell factories Explores the potential of microbial cell derived industrial production Synthesizes information on environmental and agricultural uses of microbial biotechnology Contributions from an international team of leading scholars

Engineering of Microbial Biosynthetic Pathways

Engineering of Microbial Biosynthetic Pathways Book
Author : Vijai Singh,Ajay Kumar Singh,Poonam Bhargava,Madhvi Joshi,Chaitanya G. Joshi
Publisher : Springer Nature
Release : 2020-07-16
ISBN : 9811526044
Language : En, Es, Fr & De

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Book Description :

This book provides a comprehensive overview of the basic and advanced metabolic engineering technologies used to generate natural metabolites and industrially important biomolecules. Metabolic engineering has the potential to produce large quantities of valuable biomolecules in a renewable and sustainable manner by extending or modifying biosynthetic pathways in a wide range of organisms. It has been successfully used to produce chemicals, drugs, enzymes, amino acids, antibiotics, biofuels, and industrially important pharmaceuticals. The book comprehensively reviews the various metabolites detection, extraction and biosensors and the metabolic engineering of microbial strains for the production of industrially useful enzymes, proteins, organic acids, vitamins and antibiotics, therapeutics, chemicals, and biofuels. It also discusses various genetic engineering and synthetic biology tools for metabolic engineering. In closing, the book discusses ethical, patenting and regulatory issues in the metabolic engineering of microbes. This book is a valuable source not only for beginners in metabolic engineering, but also students, researchers, biotechnology and metabolic engineering based company.

Fermentation Microbiology and Biotechnology Fourth Edition

Fermentation Microbiology and Biotechnology  Fourth Edition Book
Author : E. M. T. El-Mansi,Jens Nielsen,David Mousdale,Ross P. Carlson
Publisher : CRC Press
Release : 2018-12-17
ISBN : 042901595X
Language : En, Es, Fr & De

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Book Description :

Fermentation Microbiology and Biotechnology, 4th Edition explores and illustrates the broad array of metabolic pathways employed for the production of primary and secondary metabolites, as well as biopharmaceuticals. This updated and expanded edition addresses the whole spectrum of fermentation biotechnology, from fermentation kinetics and dynamics to protein and co-factor engineering. It also sheds light on the new strategies employed by industrialist for increasing tolerance and endurance of microorganisms to the accumulation of toxic wastes in microbial-cell factories. The new edition builds upon the fine pedigree of its earlier predecessors and extends the spectrum of the book to reflect the multidisciplinary and buoyant nature of this subject area. Key Features Covers the whole spectrum of the field from fermentation kinetics to control of fermentation and protein engineering. Includes case studies specifically designed to illustrate industrial applications and current state-of-the-art technologies. Presents the contributions of eminent international academics and industrial experts. Offers new chapters addressing: The prospects and the role of bio-fuels refineries, Control of metabolic efflux to product formation in microbial-cell factories and Improving tolerance of microorganisms to toxic byproduct accumulation in the fermentation vessel.

Microbial Nanotechnology

Microbial Nanotechnology Book
Author : Mahendra Rai,Patrycja Golińska
Publisher : CRC Press
Release : 2020-09-17
ISBN : 1000196488
Language : En, Es, Fr & De

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Book Description :

This book provides an account of the biogenic synthesis of nanomaterials by using different microorganisms. The chapters are focused on the biosynthesis of various metal and metal oxide nanosized materials by using bacteria, actinomycetes, fungi, and algae, including mechanisms of microbial synthesis. Other chapters summarize recent developments of microbial-based nanostructures for the management of food-borne pathogens, plant pathogenic fungi, as nutrients, and biomedical applications. Microorganisms are discussed not only as biofactories for the synthesis of nanomaterials but also as removal agents of toxic metals from the environment. Exposure sources and ecotoxicity of microbially synthesized nanoparticles are also discussed.

New and Future Developments in Microbial Biotechnology and Bioengineering

New and Future Developments in Microbial Biotechnology and Bioengineering Book
Author : Alexandre Gomes Rodrigues
Publisher : Elsevier
Release : 2020-06-10
ISBN : 0444643028
Language : En, Es, Fr & De

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Book Description :

New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Biomolecules: Properties, Relevance and Their Translational Applications presents a concise review on microbial biotechnology, along with impacts and recent results from research centers, small companies and large enterprises. The book brings the most relevant information on how we can use resources—in this case from microorganisms—and technology to develop solutions in fields like biofuels, food, cosmetics and medicine. It covers case studies of start-ups in the field and explains how scientists have moved their ideas into profitable bio-based products that are necessary for our current living standards. In addition, the book describes strategic governmental programs designed to exploit biomass in a sustainable way, along with detailed information on research in several high-impact, worldwide laboratories. It gives concrete examples of ongoing research from molecules to methods, such as L-asparaginase, extremophiles, new diagnostics tools and the analytical methods that have raised the quality of the data obtained, thereby boosting the so-called bioeconomy. Comprises a unique source of information on the various applications of microbial biomolecules Provides resourceful material for new ideas and strong rational/application-oriented stories Discusses biotech companies in various areas (biofuel, food, medicine, etc.) who are actively using microbial biomolecules Outlines scientific discoveries and their translation into profitable products Gives an insight perspective of institutional and governmental strategic research programs aiming to preserve, explore and generate benefits from microbial biomolecules

Algae Biotechnology

Algae Biotechnology Book
Author : Faizal Bux,Yusuf Chisti
Publisher : Springer
Release : 2016-03-09
ISBN : 3319123343
Language : En, Es, Fr & De

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Book Description :

This book examines the utilization of algae for the development of useful products and processes with the emphasis towards green technologies and processes, and the requirements to make these viable. Serving as a complete reference guide to the production of biofuels and other value added products from micro and macro algae, it covers various aspects of algal biotechnology from the basics to large scale cultivation, harvesting and processing for a variety of products. It is authored and edited by respected world experts in the field of algal biotechnology and provides the most up to date and cutting edge information on developments in the field. Over the past decade there has been substantial focus and related literature on the application of algal biomass for the generation of novel processes and products. ‘Algae Biotechnology: Products and Processes’ encompasses a holistic approach to critically evaluating developments in the field of algal biotechnology whilst taking into account recent advances and building on the body of knowledge. Aspects of the effects of harmful algae are also discussed, as well as the potential commercial application of algal biotechnology, the techno-economic feasibility of algal biodiesel production and the use of genetic and metabolic engineering for the improvement of yield. Other bioenergy sources such as alcohol fuels, aviation fuels, biohydrogen and biogas are also covered. This book is intended for postgraduates and researchers working in the biofuels and algal industry; it constitutes ideal reference material for both early stage and established researchers.

Current Developments in Biotechnology and Bioengineering

Current Developments in Biotechnology and Bioengineering Book
Author : Sudhir P. P. Singh,Ashok Pandey,Guocheng Du,Sudesh Kumar
Publisher : Elsevier
Release : 2018-11-20
ISBN : 044464086X
Language : En, Es, Fr & De

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Book Description :

Current Developments in Biotechnology and Bioengineering: Synthetic Biology, Cell Engineering and Bioprocessing Technologies covers the current perspectives and outlook of synthetic biology in the agriculture, food and health sectors. This book begins with the basics about synthetic biology and cell engineering, and then explores this in more detail, focusing on topics like applications of synthetic biology, industrial bioprocesses, and future perspectives. Information on cell engineering is also presented, and manipulation in endogenous metabolic network is studied alongside advanced topics such as fine tuning of metabolic pathways, de novo biosynthetic pathway design, enzyme engineering targeted to improved kinetics and stability, and potential applications of the novel biological systems in bioprocess technology to achieve the production of value-added compounds with specific biological activities. Assists in developing a conceptual understanding of synthetic biology and cellular and metabolic engineering. Includes comprehensive information on new developments and advancements. Lists applications of synthetic biology in agriculture, food, and health

Engineering the Microbial Platform for the Production of Biologics and Small Molecule Medicines

Engineering the Microbial Platform for the Production of Biologics and Small Molecule Medicines Book
Author : Dipesh Dhakal,Eung-Soo Kim,Mattheos Koffas
Publisher : Frontiers Media SA
Release : 2019-12-23
ISBN : 2889632539
Language : En, Es, Fr & De

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Book Description :

Download Engineering the Microbial Platform for the Production of Biologics and Small Molecule Medicines book written by Dipesh Dhakal,Eung-Soo Kim,Mattheos Koffas, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Bioprocessing for Biomolecules Production

Bioprocessing for Biomolecules Production Book
Author : Gustavo Molina,Vijai Kumar Gupta,Brahma N. Singh,Nicholas Gathergood
Publisher : John Wiley & Sons
Release : 2020-01-13
ISBN : 1119434327
Language : En, Es, Fr & De

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Book Description :

Presents the many recent innovations and advancements in the field of biotechnological processes This book tackles the challenges and potential of biotechnological processes for the production of new industrial ingredients, bioactive compounds, biopolymers, energy sources, and compounds with commercial/industrial and economic interest by performing an interface between the developments achieved in the recent worldwide research and its many challenges to the upscale process until the adoption of commercial as well as industrial scale. Bioprocessing for Biomolecules Production examines the current status of the use and limitation of biotechnology in different industrial sectors, prospects for development combined with advances in technology and investment, and intellectual and technical production around worldwide research. It also covers new regulatory bodies, laws and regulations, and more. Chapters look at biological and biotechnological processes in the food, pharmaceutical, and biofuel industries; research and production of microbial PUFAs; organic acids and their potential for industry; second and third generation biofuels; the fermentative production of beta-glucan; and extremophiles for hydrolytic enzymes productions. The book also looks at bioethanol production from fruit and vegetable wastes; bioprocessing of cassava stem to bioethanol using soaking in aqueous ammonia pretreatment; bioprospecting of microbes for bio-hydrogen production; and more. Provides up to date information about the advancements made on the production of important biotechnological ingredients Complete visualization of the general developments of world research around diverse products and ingredients of technological, economic, commercial and social importance Investigates the use and recovery of agro-industrial wastes in biotechnological processes Includes the latest updates from regulatory bodies for commercialization feasibility Offering new products and techniques for the industrial development and diversification of commercial products, Bioprocessing for Biomolecules Production is an important book for graduate students, professionals, and researchers involved in food technology, biotechnology; microbiology, bioengineering, biochemistry, and enzymology.

Lactic Acid Bacteria as Cell Factories Synthetic Biology and Metabolic Engineering

Lactic Acid Bacteria as Cell Factories  Synthetic Biology and Metabolic Engineering Book
Author : Didier Montet,Ramesh C. Ray,Vasco Ariston De Carvalho Azevedo,Spiros Paramithiotis
Publisher : Woodhead Publishing
Release : 2023-01-15
ISBN : 9780323919302
Language : En, Es, Fr & De

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Book Description :

Lactic Acid Bacteria as Cell Factories describes the most recent developments on the metabolic engineering and synthetic biology of Lactic Acid Bacteria (LAB) for production of biologically active biomolecules (enzymes, organic acids, bacteriocins, bioactive peptides, etc) and recombinant proteins, and their role in bioremediation. LAB are a heterologous group of microorganisms that have been isolated from numerous ecological niches, including fermented foods, plants, and the gastrointestinal tract of animals. Because of their "generally regarded as safe" status (GRAS), there is strong interest in using these microorganisms in functional food, feed and pharmaceutical industries, either as probiotic microorganisms, for delivery of bioactive molecules, or as biotechnological tools. Lactic Acid Bacteria as Cell Factories focuses on synthetic biology and metabolic engineering for the production of biologically active molecules such as bioactive peptides, polysaccharides, vitamins (Riboflavin), enzymes, organic acids (lactic and gamma-aminobutyric acid), flavor and aroma compounds, bacteriocins, recombinant proteins, etc. Individual chapters are devoted to the production of biosurfactants and their applications, bioremediation of heavy metals by LAB from aquatic environments. Two critical chapters address Genome editing of LAB: opportunities for food, feed and pharmaceuticals and A synthetic biology approach for plasmid DNA and Recombinant protein production. This book will be a valuable resource for those working in biology, biotechnology, biological engineering, chemical engineering, microbiology, food science and technology, genetics and synthetic biology. Explores the synthetic biology and metabolic engineering of lactic acid bacteria Highlights LAB enzymes such as phytase and amylase applications in food processing and removal of anti-nutrients from foods, and lignocellulose bioconversion Presents insights into biosurfactant production and possible applications Includes, bioremediation by LAB, biofilm production mechanism, plasmid and recombinant protein production using synthetic biology

Biotechnology of Terpenoid Production from Microbial Cell Factories

Biotechnology of Terpenoid Production from Microbial Cell Factories Book
Author : Pratima Gupta,Suresh Phulara
Publisher : Academic Press
Release : 2021-04-17
ISBN : 0128231785
Language : En, Es, Fr & De

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Book Description :

Biotechnology of Terpenoid Production from Microbial Cell Factories is a unique reference to help researchers, scientists and scholars explore available strategies involved in the production of terpenoid-based, value-added compounds from GRAS status (Generally Recognized as Safe by FDA) microbes to address the associated challenges for the industry. The book covers the most up-to-date information about microbial terpenoid production, including culture condition modulation for the improved and high-specificity production of terpenoid and their in-situ extraction. Each class of terpenoid is explained in detail, including their nutritional and pharmaceutical information and their molecular aspects. Provides an in-depth look at both the natural and metabolic engineering aspects of microbial terpenoid production Includes production strategies and existing challenges for each class of terpenoid from microbial sources Presents broad application opportunities of terpenoids such as food additives, pharmaceuticals and fragrances Includes brief chapter summaries and a glossary for each chapter to simplify technical applications

Food Engineering Innovations Across the Food Supply Chain

Food Engineering Innovations Across the Food Supply Chain Book
Author : Pablo Juliano,Kai Knoerzer,Jay Sellahewa,Minh H. Nguyen,Roman Buckow
Publisher : Academic Press
Release : 2021-12-05
ISBN : 0323853595
Language : En, Es, Fr & De

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Book Description :

Food Engineering Innovations Across the Food Supply Chain discusses the technology advances and innovations into industrial applications to improve supply chain sustainability and food security. The book captures the highlights of the 13th International Congress of Engineering ICEF13 under selected congress themes, including Sustainable Food Systems, Food Security, Advances in Food Process Engineering, Novel Food Processing Technologies, Food Process Systems Engineering and Modeling, among others. Edited by a team of distinguished researchers affiliated to CSIRO, this book is a valuable resource to all involved with the Food Industry and Academia. Feeding the world’s population with safe, nutritious and affordable foods across the globe using finite resources is a challenge. The population of the world is increasing. There are two opposed sub-populations: those who are more affluent and want to decrease their caloric intake, and those who are malnourished and require more caloric and nutritional intake. For sustainable growth, an increasingly integrated systems approach across the whole supply chain is required. Focuses on innovation across the food supply chain beyond the traditional food engineering discipline Brings the integration of on-farm with food factory operations, the inclusion of Industry 4.0 sensing technologies and Internet of Things (IoT) across the food chain to reduce food wastage, water and energy inputs Makes a full intersection into other science domains (operations research, informatics, agriculture and agronomy, machine learning, artificial intelligence and robotics, intelligent packaging, among others)

Bioethanol

Bioethanol Book
Author : Ayerim Y. Hernández Almanza,Nagamani Balagurusamy,Héctor Ruiz Leza,Cristóbal N. Aguilar
Publisher : CRC Press
Release : 2022-07-07
ISBN : 1000565130
Language : En, Es, Fr & De

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Book Description :

This new book, Bioethanol: Biochemistry and Biotechnological Advances, presents some insightful perspectives and important advances in the bioethanol industry. The volume goes into detail on the biochemical and physiological parameters carried out by the main bioethanol-producing microorganisms as well as the discusses the potential applications that bioproducts can have and the advantages they generate. The chapter authors discuss a variety of issues, including the physiology of ethanol production by yeasts, by Zymomonas mobilis, and by Clostridium thermocellum. Other sources of biofuel, such as sweet sorghum, Agave americana L. leaves waste, and fungi are included as well. Chapters also discuss the genetic regulation and genetic engineering of principal microorganisms and then go on to address ways to increase ethanol tolerance in industrially important ethanol fermenting organisms, methods for developing sustainable fermentable substrates, and new strategies for ethanol purification. Chapters explore the design and engineering requirements for bioreactors, bioelectrosynthesis of ethanol via bioelectrochemical systems, and more. The book will be a valuable resource for faculty and students in this area as well as for scientists, researchers, and managers in the biofuel industry in the area of biofuel production, fermentation process, environmental engineering and all other related scientific areas.

Biofuels

Biofuels Book
Author : Xuefeng Lu
Publisher : Unknown
Release : 2014-07-01
ISBN : 9781908230454
Language : En, Es, Fr & De

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Book Description :

"In this book a panel of international experts reviews the most important hot-topics in this area to provide a timely overview. The production of different biofuel molecules including hydrogen, methane, ethanol, butanol, higher chain alcohols, isoprenoids and fatty acid derivatives, from genetically engineered microbes, is comprehensively covered. Special focus is given to the use of metabolic engineering of microbes, including bacteria, yeast and microalgae, to enhance biofuel production. In addition authors discuss current research processes, technical challenges and future development trends for biofuel production."--Back cover.

Non conventional Yeasts from Basic Research to Application

Non conventional Yeasts  from Basic Research to Application Book
Author : Andriy Sibirny
Publisher : Springer
Release : 2019-08-12
ISBN : 303021110X
Language : En, Es, Fr & De

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Book Description :

This volume scopes several aspects of non-conventional yeast research prepared by the leading specialists in the field. An introduction on taxonomy and systematics enhances the reader’s knowledge on yeasts beyond established ones such as Saccharomyces cerevisiae. Biotechnological approaches that involve fungal utilization of unusual substrates, production of biofuels and useful chemicals as citric acid, glutathione or erythritol are discussed. Further, strategies for metabolic engineering based on knowledge on regulation of gene expression as well as sensing and signaling pathways are presented. The book targets researchers and advanced students working in Microbiology, Microbial Biotechnology and Biochemistry.

Microbial Cell Factories

Microbial Cell Factories Book
Author : Deepansh Sharma,Baljeet Singh Saharan
Publisher : CRC Press
Release : 2018-03-22
ISBN : 1351668048
Language : En, Es, Fr & De

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Book Description :

Microbial Cell Factories is a conceptual, reference-based source including chapters covering microbial cell factories for industrial developments, microbial biotechnology, sustainable environmental solutions, agriculture practices, microorganisms in food processing, metabolites as next generation food additives/food processing, and microbial cell factories in alternative energy fuel generation. The book highlights trends and developments in the field of microbial products, written by an international team of leading academic and research scholars. Key Selling Features: Highlights trends and developments in microbial biotechnology Systematically reviews microbial cell factories Explores the potential of microbial cell derived industrial production Synthesizes information on environmental and agricultural uses of microbial biotechnology Contributions from an international team of leading scholars