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Micro Drops And Digital Microfluidics

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Micro Drops and Digital Microfluidics

Micro Drops and Digital Microfluidics Book
Author : Jean Berthier
Publisher : William Andrew
Release : 2012-12-31
ISBN : 1455728004
Language : En, Es, Fr & De

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Book Description :

In this 2nd edition of Micro-Drops and Digital Microfluidics, Jean Berthier explores the fundamentals and applications of digital microfluidics, enabling engineers and scientists to design this important enabling technology into devices and harness the considerable potential of digital microfluidics in testing and data collection. This book describes the most recent developments in digital microfluidics, with a specific focus on the computational, theoretical and experimental study of microdrops. Unique in its emphasis on digital microfluidics and with diverse applications ranging from drug delivery to point-of-care diagnostic chips, organic synthesis to microreactors, Micro-Drops and Digital Microfluidics meets the needs of audiences across the fields of bioengineering and biotechnology, and electrical and chemical engineering. Authoritative reporting on the latest changes in microfluidic science, where microscopic liquid volumes are handled as ""microdrops"" and separately from ""nanodrops." A methodical examination of how liquid microdrops behave in the complex geometries of modern miniaturized systems and interact with different morphological (micro-fabricated, textured) solid substrates A thorough explanation of how capillary forces act on liquid interfaces in contact with micro-fabricated surfaces Analysis of how droplets can be manipulated, handled, or transported using electric fields (electrowetting), acoustic actuation (surface acoustic waves), or by a carrier liquid (microflow) A fresh perspective on the future of microfluidics

Micro Drops and Digital Microfluidics

Micro Drops and Digital Microfluidics Book
Author : Jean Berthier
Publisher : Elsevier
Release : 2008-03-20
ISBN : 0815518358
Language : En, Es, Fr & De

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Book Description :

After spending over 12 years developing new microsystems for biotechnology – especially concerned with the microfluidic aspects of these devices – Jean Berthier is considered a leading authority in the field. Now, following the success of his book, Microfluidics for Biotechnology, Dr. Berthier returns to explain how new miniaturization techniques have dramatically expanded the area of microfluidic applications and microsystems into microdrops and digital microfluidics. Engineers interested in designing more versatile microsystems and students who seek to learn the fundamentals of microfluidics will all appreciate the wide-range of information found within Microdrops and Digital Microfluidics. The most recent developments in digital microfluidics are described in clear detail, with a specific focus on the computational, theoretical and experimental study of microdrops. • Over 500 equations and more than 400 illustrations. • Authoritative reporting on the latest changes in microfluidic science, where microscopic liquid volumes are handled as ""microdrops"" and separately from ""nanodrops."" • A methodical examination of how liquid microdrops behave in the complex geometries of modern miniaturized systems and interact with different morphological (micro-fabricated, textured) solid substrates. • A thorough explanation of how capillary forces act on liquid interfaces in contact with micro-fabricated surfaces. • Analysis of how droplets can be manipulated, handled, or transported using electric fields (electrowetting), acoustic actuation (surface acoustic waves), or by a carrier liquid (microflow). • A fresh perspective on the future of microfluidics.

Microfluidics for Biotechnology

Microfluidics for Biotechnology Book
Author : Jean Berthier,Pascal Silberzan
Publisher : Artech House
Release : 2010
ISBN : 1596934441
Language : En, Es, Fr & De

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Book Description :

The application of microfluidics to biotechnology is an exciting new area that has already begun to revolutionize how researchers study and manipulate macromolecules like DNA, proteins and cells in vitro and within living organisms. Now in a newly revised and expanded second edition, the Artech House bestseller, Microfluidics for Biotechnology brings you to the cutting edge of this burgeoning field. Among the numerous updates, the second edition features three entirely new chapters on: non-dimensional numbers in microfluidics; interface, capillarity and microdrops; and digital, two-phase and droplet microfluidics.Presenting an enlightening balance of numerical approaches, theory, and experimental examples, this book provides a detailed look at the mechanical behavior of the different types of micro/nano particles and macromolecules that are used in biotechnology. You gain a solid understanding of microfluidics theory and the mechanics of microflows and microdrops. The book examines the diffusion of species and nanoparticles, including continuous flow and discrete Monte-Carlo methods.This unique volume describes the transport and dispersion of biochemical species and particles. You learn how to model biochemical reactions, including DNA hybridization and enzymatic reactions. Moreover, the book helps you master the theory, applications, and modeling of magnetic beads behavior and provides an overview of self-assembly and magnetic composite. Other key topics include the electric manipulation of micro/nanoparticles and macromolecules and the experimental aspects of biological macromolecule manipulation.

The Physics of Microdroplets

The Physics of Microdroplets Book
Author : Jean Berthier,Kenneth A. Brakke
Publisher : John Wiley & Sons
Release : 2012-04-30
ISBN : 1118401336
Language : En, Es, Fr & De

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Book Description :

The Physics of Microdroplets gives the reader the theoretical and numerical tools to understand, explain, calculate, and predict the often nonintuitive observed behavior of droplets in microsystems. Microdrops and interfaces are now a common feature in most fluidic microsystems, from biology, to biotechnology, materials science, 3D-microelectronics, optofluidics, and mechatronics. On the other hand, the behavior of droplets and interfaces in today's microsystems is complicated and involves complex 3D geometrical considerations. From a numerical standpoint, the treatment of interfaces separating different immiscible phases is difficult. After a chapter dedicated to the general theory of wetting, this practical book successively details: The theory of 3D liquid interfaces The formulas for volume and surface of sessile and pancake droplets The behavior of sessile droplets The behavior of droplets between tapered plates and in wedges The behavior of droplets in microchannels The effect of capillarity with the analysis of capillary rise The onset of spontaneous capillary flow in open microfluidic systems The interaction between droplets, like engulfment The theory and application of electrowetting The state of the art for the approach of 3D-microelectronics using capillary alignment

VLSI Design and Test

VLSI Design and Test Book
Author : Brajesh Kumar Kaushik,Sudeb Dasgupta,Virendra Singh
Publisher : Springer
Release : 2017-12-21
ISBN : 9811074704
Language : En, Es, Fr & De

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Book Description :

This book constitutes the refereed proceedings of the 21st International Symposium on VLSI Design and Test, VDAT 2017, held in Roorkee, India, in June/July 2017. The 48 full papers presented together with 27 short papers were carefully reviewed and selected from 246 submissions. The papers were organized in topical sections named: digital design; analog/mixed signal; VLSI testing; devices and technology; VLSI architectures; emerging technologies and memory; system design; low power design and test; RF circuits; architecture and CAD; and design verification.

Mechatronics and Computational Mechanics

Mechatronics and Computational Mechanics Book
Author : Sally Gao
Publisher : Trans Tech Publications Ltd
Release : 2013-02-13
ISBN : 3038260401
Language : En, Es, Fr & De

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Book Description :

The collection includes selected, peer reviewed papers from the 2012 International Conference on Mechatronics and Computational Mechanics (ICMCM 2012), 20-21st December,2012, Dubai, UAE. Volume is indexed by Thomson Reuters CPCI-S (WoS). The papers are grouped as follows: Chapter 1: Mechatronics and Control; Chapter 2: Applied Mechanics and Mechanical Engineering; Chapter 3: Applied Materials Engineering; Chapter 4: Organization of Manufacture, Engineering Management and Information Technologies.

Formal Modeling and Verification of Cyber Physical Systems

Formal Modeling and Verification of Cyber Physical Systems Book
Author : Rolf Drechsler,Ulrich Kühne
Publisher : Springer
Release : 2015-06-05
ISBN : 3658099941
Language : En, Es, Fr & De

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Book Description :

This book presents the lecture notes of the 1st Summer School on Methods and Tools for the Design of Digital Systems, 2015, held in Bremen, Germany. The topic of the summer school was devoted to modeling and verification of cyber-physical systems. This covers several aspects of the field, including hybrid systems and model checking, as well as applications in robotics and aerospace systems. The main chapters have been written by leading scientists, who present their field of research, each providing references to introductory material as well as latest scientific advances and future research directions. This is complemented by short papers submitted by the participating PhD students.

Advances in Optofluidics

Advances in Optofluidics Book
Author : Xuming Zhang
Publisher : MDPI
Release : 2018-08-15
ISBN : 3038970956
Language : En, Es, Fr & De

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Book Description :

This book is a printed edition of the Special Issue "Advances in Optofluidics" that was published in Micromachines

Open Channel Microfluidics

Open Channel Microfluidics Book
Author : Jean Berthier,Ashleigh B Theberge,Erwin Berthier
Publisher : Morgan & Claypool Publishers
Release : 2019-09-04
ISBN : 1643276646
Language : En, Es, Fr & De

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Book Description :

Open microfluidics, the study of microflows having a boundary with surrounding air, encompasses different aspects such as paper or thread-based microfluidics, droplet microfluidics and open-channel microfluidics. Open-channel microflow is a flow at the micro-scale, guided by solid structures, and having at least a free boundary (with air or vapor) other than the advancing meniscus. This book is devoted to the study of open-channel microfluidics which (contrary to paper or thread or droplet microfluidics) is still very sparsely documented, but bears many new applications in biology, biotechnology, medicine, material and space sciences. Capillarity being the principal force triggering an open microflow, the principles of capillarity are first recalled. The onset of open-channel microflow is next analyzed and the fundamental notion of generalized Cassie angle (the apparent contact angle which accounts for the presence of air) is presented. The theory of the dynamics of open-channel microflows is then developed, using the notion of averaged friction length which accounts for the presence of air along the boundaries of the flow domain. Different channel morphologies are studied and geometrical features such as valves and capillary pumps are examined. An introduction to two-phase open-channel microflows is also presented showing that immiscible plugs can be transported by an open-channel flow. Finally, a selection of interesting applications in the domains of space, materials, medicine and biology is presented, showing the potentialities of open-channel microfluidics.

Micro Electrode Dot Array Digital Microfluidic Biochips

Micro Electrode Dot Array Digital Microfluidic Biochips Book
Author : Zipeng Li,Krishnendu Chakrabarty,Tsung-Yi Ho,Chen-Yi Lee
Publisher : Springer
Release : 2018-12-14
ISBN : 3030029646
Language : En, Es, Fr & De

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Book Description :

This book provides an insightful guide to the design, testing and optimization of micro-electrode-dot-array (MEDA) digital microfluidic biochips. The authors focus on the characteristics specific for MEDA biochips, e.g., real-time sensing and advanced microfluidic operations like lamination mixing and droplet shape morphing. Readers will be enabled to enhance the automated design and use of MEDA and to develop a set of solutions to facilitate the full exploitation of design complexities that are possible with standard CMOS fabrication techniques. The book provides the first set of design automation and test techniques for MEDA biochips. The methods described in this book have been validated using fabricated MEDA biochips in the laboratory. Readers will benefit from an in-depth look at the MEDA platform and how to combine microfluidics with software, e.g., applying biomolecular protocols to software-controlled and cyberphysical microfluidic biochips.

Interfacial Fluid Mechanics

Interfacial Fluid Mechanics Book
Author : Vladimir S. Ajaev
Publisher : Springer Science & Business Media
Release : 2012-02-07
ISBN : 1461413419
Language : En, Es, Fr & De

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Book Description :

Interfacial Fluid Mechanics: A Mathematical Modeling Approach provides an introduction to mathematical models of viscous flow used in rapidly developing fields of microfluidics and microscale heat transfer. The basic physical effects are first introduced in the context of simple configurations and their relative importance in typical microscale applications is discussed. Then, several configurations of importance to microfluidics, most notably thin films/droplets on substrates and confined bubbles, are discussed in detail. Topics from current research on electrokinetic phenomena, liquid flow near structured solid surfaces,evaporation/condensation, and surfactant phenomena are discussed in the later chapters.

Micro Segmented Flow

Micro Segmented Flow Book
Author : J. Michael Köhler,Brian P. Cahill
Publisher : Springer Science & Business Media
Release : 2013-11-08
ISBN : 3642387802
Language : En, Es, Fr & De

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Book Description :

The book is dedicated to the method and application potential of micro segmented flow. The recent state of development of this powerful technique is presented in 12 chapters by leading researchers from different countries. In the first section, the principles of generation and manipulation of micro-fluidic segments are explained. In the second section, the micro continuous-flow synthesis of different types of nanomaterials is shown as a typical example for the use of advantages of the technique in chemistry. In the third part, the particular importance of the technique in biotechnical applications is presented demonstrating the progress for miniaturized cell-free processes, for molecular biology and DNA-based diagnostics and sequencing as well as for the development of antibiotics and the evaluation of toxic effects in medicine and environment.

Microfluidics in Detection Science

Microfluidics in Detection Science Book
Author : Fatima H Labeed,Henry O Fatoyinbo
Publisher : Royal Society of Chemistry
Release : 2014-10-24
ISBN : 1849737606
Language : En, Es, Fr & De

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Book Description :

The concept of a miniaturised laboratory on a disposable chip is now a reality, and in everyday use in industry, medicine and defence. New devices are launched all the time, prompting the need for a straightforward guide to the design and manufacture of lab-on-a-chip (LOC) devices. This book presents a modular approach to the construction and integration of LOC components in detection science. The editors have brought together some of the leading experts from academia and industry to present an accessible guide to the technology available and its potential. Several chapters are devoted to applications, presenting both the sampling regime and detection methods needed. Further chapters describe the integration of LOC devices, not only with each other but also into existing technologies. With insights into LOC applications, from biosensing to molecular and chemical analysis, and presenting scaled-down versions of existing technology alongside unique approaches that exploit the physics of the micro and nano-scale, this book will appeal to newcomers to the field and practitioners requiring a convenient reference.

Nanotechnology Environmental Health and Safety

Nanotechnology Environmental Health and Safety Book
Author : Matthew Hull,Diana Bowman
Publisher : Elsevier
Release : 2009-11-17
ISBN : 9780815519829
Language : En, Es, Fr & De

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Book Description :

This book tackles the debate over nanotechnology's environmental health and safety (EHS) by thoroughly explaining EHS issues, financial implications, foreseeable risks (i.e. exposure, dose, hazards of nanomaterials), and the implications of occupational hygiene precautions and consumer protections. Real-world case studies are included, e.g. the discussion of a leading chemical company's unusual pairing with the USA's largest environmental NGO, and an innovative program designed for small- to mid-sized businesses, which became a model approach for proactive nanotechnology EHS risk management. Considers the potential of nanotechnology from multiple perspectives (NGO, insurance industry, small business, etc) Provides guidance and advice for appropriate, proactive risk management strategies Reviews toxicological studies and industrial initiatives, documented with actual case studies Of significant interest to CEOs/CTOs of technology companies (SMEs), Health and Safety officers of technology companies (SMEs), Government officials (HSE), Toxicology experts, and venture capitalists

Algorithmic Foundations of Robotics VI

Algorithmic Foundations of Robotics VI Book
Author : Michael Erdmann,David Hsu,Mark Overmars,A. Frank van der Stappen
Publisher : Springer Science & Business Media
Release : 2005-06-23
ISBN : 9783540257288
Language : En, Es, Fr & De

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Book Description :

Robot algorithms are abstractions of computational processes that control or reason about motion and perception in the physical world. Because actions in the physical world are subject to physical laws and geometric constraints, the design and analysis of robot algorithms raise a unique combination of questions in control theory, computational and differential geometry, and computer science. Algorithms serve as a unifying theme in the multi-disciplinary field of robotics. This volume consists of selected contributions to the sixth Workshop on the Algorithmic Foundations of Robotics. This is a highly competitive meeting of experts in the field of algorithmic issues related to robotics and automation.

Proceedings

Proceedings Book
Author : N.A
Publisher :
Release : 2003
ISBN :
Language : En, Es, Fr & De

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Book Description :

Nanotechnology Applications for Clean Water

Nanotechnology Applications for Clean Water Book
Author : Mamadou Diallo,Jeremiah Duncan
Publisher : William Andrew
Release : 2009
ISBN :
Language : En, Es, Fr & De

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Book Description :

"In this truly unique reference, over 80 leading experts from the global scientific community share their research and knowledge to address the global challenges of water quality and remediation in the hopes that nanotechnology can ensure that clean water is available to everyone."--BOOK JACKET.

Design and Testing of Digital Microfluidic Biochips

Design and Testing of Digital Microfluidic Biochips Book
Author : Yang Zhao,Krishnendu Chakrabarty
Publisher : Springer Science & Business Media
Release : 2012-07-25
ISBN : 1461403707
Language : En, Es, Fr & De

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Book Description :

This book provides a comprehensive methodology for automated design, test and diagnosis, and use of robust, low-cost, and manufacturable digital microfluidic systems. It focuses on the development of a comprehensive CAD optimization framework for digital microfluidic biochips that unifies different design problems. With the increase in system complexity and integration levels, biochip designers can utilize the design methods described in this book to evaluate different design alternatives, and carry out design-space exploration to obtain the best design point.