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Micro And Nanotechnology In Vaccine Development

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Micro and Nanotechnology in Vaccine Development

Micro  and Nanotechnology in Vaccine Development Book
Author : Mariusz Skwarczynski,Istvan Toth
Publisher : William Andrew
Release : 2016-09-20
ISBN : 0323400299
Language : En, Es, Fr & De

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Book Description :

This book provides a comprehensive overview of how use of micro- and nanotechnology (MNT) has allowed major new advance in vaccine development research, and the challenges that immunologists face in making further progress. MNT allows the creation of particles that exploit the inherent ability of the human immune system to recognize small particles such as viruses and toxins. In combination with minimal protective epitope design, this permits the creation of immunogenic particles that stimulate a response against the targeted pathogen. The finely tuned response of the human immune system to small particles makes it unsurprising that many of the lead adjuvants and vaccine delivery systems currently under investigation are based on nanoparticles. Provides a comprehensive and unparalleled overview of the role of micro- and nanotechnology in vaccine development Allows researchers to quickly familiarize themselves with the broad spectrum of vaccines and how micro- and nanotechnologies are applied to their development Includes a combination of overview chapters setting out general principles, and focused content dealing with specific vaccines, making it useful to readers from a variety of disciplines

The Nano Micro Interface 2 Volumes

The Nano Micro Interface  2 Volumes Book
Author : Marcel Van de Voorde,Matthias Werner,Hans-Jörg Fecht
Publisher : John Wiley & Sons
Release : 2015-01-12
ISBN : 3527679219
Language : En, Es, Fr & De

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Book Description :

Controlling the properties of materials by modifying their composition and by manipulating the arrangement of atoms and molecules is a dream that can be achieved by nanotechnology. As one of the fastest developing and innovative -- as well as well-funded -- fields in science, nanotechnology has already significantly changed the research landscape in chemistry, materials science, and physics, with numerous applications in consumer products, such as sunscreens and water-repellent clothes. It is also thanks to this multidisciplinary field that flat panel displays, highly efficient solar cells, and new biological imaging techniques have become reality. This second, enlarged edition has been fully updated to address the rapid progress made within this field in recent years. Internationally recognized experts provide comprehensive, first-hand information, resulting in an overview of the entire nano-micro world. In so doing, they cover aspects of funding and commercialization, the manufacture and future applications of nanomaterials, the fundamentals of nanostructures leading to macroscale objects as well as the ongoing miniaturization toward the nanoscale domain. Along the way, the authors explain the effects occurring at the nanoscale and the nanotechnological characterization techniques. An additional topic on the role of nanotechnology in energy and mobility covers the challenge of developing materials and devices, such as electrodes and membrane materials for fuel cells and catalysts for sustainable transportation. Also new to this edition are the latest figures for funding, investments, and commercialization prospects, as well as recent research programs and organizations.

Molecular Vaccines

Molecular Vaccines Book
Author : Matthias Giese
Publisher : Springer Science & Business Media
Release : 2013-11-08
ISBN : 3319009788
Language : En, Es, Fr & De

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Book Description :

This title discusses all aspects of non-infectious and non-cancer– so called NINC – vaccines. Hypertension, diabetes and allergy vaccine development are referred to as well as the use of adjuvants and nanotechnology in vaccine development. The way of novel vaccines from bench to preclinical to clinical studies and launch to the market under EMEA (European Medicines Agency) and FDA (Food and Drug Administration) guidelines are described in-depth. The book is therefore of interest for researchers and clinicians engaged in vaccine development and molecular vaccine application.

Journal of Nanoscience and Nanotechnology

Journal of Nanoscience and Nanotechnology Book
Author : Anonim
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Introduction to Nanoscience and Nanotechnology

Introduction to Nanoscience and Nanotechnology Book
Author : Gabor L. Hornyak,H.F. Tibbals,Joydeep Dutta,John J. Moore
Publisher : CRC Press
Release : 2009
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

PerspectivesIntroductionNanoscience and Nanotechnology-The DistinctionHistorical PerspectivesAdvanced MaterialsTools of NanoNature's Take on Nano and the Advent of Molecular BiologyThe Nano PerspectiveSocietal Implications of NanoIntroduction to Societal IssuesEthical ImplicationsLegal ImplicationsEnvironmental ImplicationsPublic PerceptionFuture of Nanotechnology NanotoolsCharacterization MethodsCharacterization of NanomaterialsElectron Probe MethodsScanning Probe Microscopy MethodsSpectroscopic MethodsNonradiative and Nonelectron Characterization MethodsFabrication MethodsFabrication of Nano.

Emerging Nanotechnologies in Immunology

Emerging Nanotechnologies in Immunology Book
Author : Ranjita Shegokar,Eliana B. Souto
Publisher : William Andrew
Release : 2018-05-17
ISBN : 0323401139
Language : En, Es, Fr & De

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Book Description :

Emerging Nanotechnologies in Immunology: The Design, Applications and Toxicology of Nanopharmaceuticals and Nanovaccines aims to deliver a systematic and comprehensive review of data concerning the nature of interaction and nano-related risks between the nanopharmaceuticals currently in the pipeline of S&T development for skin, ocular and nasal drug delivery, including absorption, toxicity, and the ability to distribute after systemic exposure. The book's contributors address a representative set of the broad spectrum of nanopharmaceutics presently being used, including cationic lipid nanoparticles, polymeric PLGA, PLA nanoparticles, biomacromolecules-based nanoparticles, and other scaffolds tissue-engineered skin substitutes. In addition, regulation and risk are also covered since the safety of these nanopharmaceuticals still represents a barrier to their wide and innovative use. Provides a thorough knowledge of the safety aspects of nanopharmaceuticals currently under research Focuses on the characterization and quantification of nanopharmaceutics to allow readers to understand the correlation between the nature of the materials and their potential nanotoxicological effects Includes a thorough overview of legal and regulatory aspects and a discussion of the ethical issues related to the R&D of nanopharmaceuticals

Nanotechnology Based Approaches for Targeting and Delivery of Drugs and Genes

Nanotechnology Based Approaches for Targeting and Delivery of Drugs and Genes Book
Author : Vijay Mishra,Prashant Kesharwani,Mohd Cairul Iqbal Mohd Amin,Arun Iyer
Publisher : Academic Press
Release : 2017-05-23
ISBN : 0128097183
Language : En, Es, Fr & De

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Book Description :

Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes provides an overview of the important aspects of nanomedicine in order to illustrate how to design and develop novel and effective drug delivery systems using nanotechnology. The book is organized into three sections, beginning with an introduction to nanomedicine and its associated issues. Section two discusses the latest technologies in nanomedicine, while the third section covers future developments and challenges in the field. By focusing on the design, synthesis, and application of a variety of nanocarriers in drug and gene delivery, this book provides pharmaceutical and materials science students, professors, clinical researchers, and industry scientists with a valuable resource aimed at tackling the challenges of delivering drugs and genes in a more targeted manner. Explores a wide range of promising approaches for the diagnosis and treatment of diseases using the latest advances in cutting-edge nanomedical technologies Contains contributions from world-renowned experts and researchers working in the area of nanomedicine and drug delivery Covers the associated challenges and potential solutions to working with nanotechnology in drug delivery Highlights crucial topics, such as biopharmaceutical and toxicity issues, quality by design, drug targeting, and more

Nanotechnology and Nanomaterial Applications in Food Health and Biomedical Sciences

Nanotechnology and Nanomaterial Applications in Food  Health  and Biomedical Sciences Book
Author : Deepak Kumar Verma,Megh R. Goya,Hafiz Anasr Rasul Suleria
Publisher : CRC Press
Release : 2019-08-23
ISBN : 0429758685
Language : En, Es, Fr & De

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Book Description :

This new volume discusses the multitude of possibilities for new development in nanotechnology that focuses on overcoming the problems and challenges faced by the biomedical and food industries. The volume hopes to facilitate the development of devices and materials that benefit patients and their healthcare. The book is broken into three parts that cover: nanotechnology techniques for biomedical applications nanoparticles and materials for food, health, and pharmaceutical application potential applications of nanotechnology in food safety

Research EU

Research EU Book
Author : Anonim
Publisher : Unknown
Release : 2009
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Nano Carrier Systems

Nano Carrier Systems Book
Author : Goutam Rath,Amit K Goyal
Publisher : Pharmamed Press
Release : 2017-07-04
ISBN : 9789386819659
Language : En, Es, Fr & De

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Book Description :

Nano-Carrier Systems: Theories, Methods, and Applications is a comprehensive overview of nanomaterials fabrication, characterization, pharmaceutical application and also an exhaustive of discussion describing toxicity issues related with various existing nanoparticles. Chapter beginning with a brief introduction describing the different and diverse nanocarriers that includes Solid Lipid Nanoparticles, Metal Nanoparticles, Liposomes, Niosomes, Dendrimers, Nanocapsules, Aquasomes, Nanosuspensions, Microemulsions, Hydrogels, Nanofibers, ISCOMs, Polymeric Nanoparticles, and Polysaccharide Nanoparticles. The last section covers the emerging application in the areas of tissue engineering, imaging, which is critical to targeted delivery of the drug, as well as to evaluation of drug efficacy. This book aims to ease the superficial difficulties of fundamental designing of nano-carriers through schematic presentation, and illustration involved in formulation and evaluation of pharmaceuticals and biopharmaceuticals. The book has been prepared to introduce undergraduates to the technologies underpinning these emerging and existing products, provide a reference volume for graduate scholars seeking an introduction to the fields of pharmaceutical nanoscience and pharmaceutical nanotechnology and provide the expert with accessible information on complementary areas. Salient Features Cover all polymeric, lipidic and metallic inorganic nano-carriers concurring the inclusive requirement for students, researcher and technocrat. Comprehensive overview of nanomaterials fabrication, characterization and pharmaceutical application. Make the understanding simple with the help of schematic diagrams, figures and tables. Number of examples related to use of polymers, lipids, polysaccharides, metals. Thorough details of characterization techniques. Covers both pharmaceuticals and biopharmaceutics aspects of nanomaterials. Contents: 1. Introduction to Nanotechnology, 2. Liposomes: Targeted and Controlled Novel Carrier System, 3. Niosomes, 4. Solid Lipid Nanoparticles, 5.Microemulsions, 6. Immunostimulating Complexes (ISCOMs), 7.Nanocapsules as Drug Delivery Agent, 8. Nanofibers, 9. Dendrimers, 10.Hydrogels: Scaffold for Drug Delivery, 11. Nanosuspensions in Drug Delivery, 12. Aquasomes: A Nano-Particulate Delivery Vehicle for Proteins, 13. Metal Nanoparticles, 14. Synthetic Polymeric Nanoparticles as Carrier for Vaccine Delivery, 15. Polysaccharide Nanoparticles in Mucosal Drug Delivery 16. Modern Nanoparticle Characterization Tools. 17.Nanotoxicology A Major Concern: Current Status

BayBio

BayBio Book
Author : Matthew M. Gardner,Andrea M. Strnad
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download BayBio book written by Matthew M. Gardner,Andrea M. Strnad, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Therapeutic Applications of Cell Microencapsulation

Therapeutic Applications of Cell Microencapsulation Book
Author : Jose Luis Pedraz,Gorka Orive
Publisher : Springer
Release : 2010-01-12
ISBN : 9781441957856
Language : En, Es, Fr & De

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Book Description :

The advancement of science is ever more contingent upon the interaction of experts vast amount of scientific information being gathered every day that exceeds the ability of any one scientist to acquire. As an illustration of the frantic pace of scientific disc- more acute in the case of scientific fields at the interface of different and seemingly distant areas of study. Amidst these, the field of cell encapsulation brings together an array of diverse disciplines such as molecular biology and biopolymers, gene therapy and inorganic membranes, stem cell biology and physicochemistry, immunology and nanotechnology. Clearly, such range of topics is too broad for any individual scientist the state-of-the-art in the field of cell encapsulation. At the core of this technology, there is an interaction of physicochemical and biological elements forming three distinct layers of complexity. First, the chemistry of the biopolymer dictates the degree of protein adsorption, vascularization, tox- ity and biocompatibility of the microcapsules. Advances in biopolymer science are providing solutions to overcome existing challenges and to improve microcapsules as delivery vehicles. Second, the choice of cells, and more precisely the plethora of in determining the immune response elicited by the host to implanted microcapsules.

Directory of Graduate Research

Directory of Graduate Research Book
Author : American Chemical Society. Committee on Professional Training
Publisher : Unknown
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.

Innovation and Technology Transfer

Innovation and Technology Transfer Book
Author : Anonim
Publisher : Unknown
Release : 1995
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Biomimetic Lipid Membranes Fundamentals Applications and Commercialization

Biomimetic Lipid Membranes  Fundamentals  Applications  and Commercialization Book
Author : Fatma N. Kök,Ahu Arslan Yildiz,Fatih Inci
Publisher : Springer
Release : 2019-04-16
ISBN : 3030115968
Language : En, Es, Fr & De

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Book Description :

This book compiles the fundamentals, applications and viable product strategies of biomimetic lipid membranes into a single, comprehensive source. It broadens its perspective to interdisciplinary realms incorporating medicine, biology, physics, chemistry, materials science, as well as engineering and pharmacy at large. The book guides readers from membrane structure and models to biophysical chemistry and functionalization of membrane surfaces. It then takes the reader through a myriad of surface-sensitive techniques before delving into cutting-edge applications that could help inspire new research directions. With more than half the world's drugs and various toxins targeting these crucial structures, the book addresses a topic of major importance in the field of medicine, particularly biosensor design, diagnostic tool development, vaccine formulation, micro/nano-array systems, and drug screening/development. Provides fundamental knowledge on biomimetic lipid membranes; Addresses some of biomimetic membrane types, preparation methods, properties and characterization techniques; Explains state-of-art technological developments that incorporate microfluidic systems, array technologies, lab-on-a-chip-tools, biosensing, and bioprinting techniques; Describes the integration of biomimetic membranes with current top-notch tools and platforms; Examines applications in medicine, pharmaceutical industry, and environmental monitoring.

Advanced Biomaterials and Biodevices

Advanced Biomaterials and Biodevices Book
Author : Ashutosh Tiwari,Anis N. Nordin
Publisher : John Wiley & Sons
Release : 2014-06-30
ISBN : 1118774132
Language : En, Es, Fr & De

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Book Description :

This cutting-edge book focuses on the emerging area ofbiomaterials and biodevices that incorporate therapeutic agents,molecular targeting, and diagnostic imaging capabilities The design and development of biomaterials play a significantrole in the diagnosis, treatment, and prevention of diseases. Whenused with highly selective and sensitive biomaterials, cutting-edgebiodevices can allow the rapid and accurate diagnosis of disease,creating a platform for research and development, especially in thefield of treatment for prognosis and detection of diseases in theearly stage. This book emphasizes the emerging area of biomaterialsand biodevices that incorporate therapeutic agents, moleculartargeting, and diagnostic imaging capabilities. The 15 comprehensive chapters written by leading experts coversuch topics as: The use of severe plastic deformation technique to enhance theproperties of nanostructured metals Descriptions of the different polymers for use in controlleddrug release Chitin and chitosan as renewable healthcare biopolymers forbiomedical applications Innovated devices such as “label-free biochips” andpolymer MEMS Molecular imprinting and nanotechnology Prussian Blue biosensing applications The evaluation of different types of biosensors in terms oftheir cost effectiveness, selectivity, and sensitivity Stimuli-responsive polypeptide nanocarriers for malignancytherapeutics

Development of Micro and Nanoparticle Substrates for SERS Detection of Pesticides and Delivery of Chemotherapeutic Drugs and Pilot Scale Process Development and Production of Cancer Testis Antigens

Development of Micro and Nanoparticle Substrates for SERS Detection of Pesticides and Delivery of Chemotherapeutic Drugs and Pilot Scale Process Development and Production of Cancer Testis Antigens Book
Author : Cameron Lee Bardliving
Publisher : Unknown
Release : 2013
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Detection or delivery of a diverse range of biomolecules in field portable devices is an important area of research in the fields of environmental pollution, homeland security, and medicine. The demand for hand-held and low cost detection in these fields has led to the development of novel analytical systems such as Surface Enhanced Raman Spectroscopy (SERS) and Molecularly Imprinted Polymers (MIP). SERS is rapidly emerging as a tool for biological assays, chemical sensing, and electrochemistry. Whereas, Molecularly Imprinted Polymers have been developed as systems for solid phase extraction, chemical separation, and controlled release. In this dissertation, several systems were developed using nanotechnology and polymer synthesi s to develop chemical sensors and a drug delivery system. A substrate for pesticide detection was developed by conjugating oligonucleotides specific for the pesticide malathion to the surface of a SERS substrate that detected the organophosphorus pesticide malathion down to the micromolar level. A SERS substrate was also developed by grafting a molecularly imprinted polymer of methacrylic acid and ethylene glycol dimethacrylate to surface of a gold coated silica microparticle that was able to capture and detect the pesticide thiabendazole. Molecularly ii imprinted polymers were investigated as a drug delivery system for the chemotherapeutic doxorubicin which showed strong imprinting and temperature sensitive controlled release of drug. Lastly, a cGMP pilot scale process was developed to produce gram levels of the cancer vaccine Melan-A for phase I clinical trials. iii.

Application of Nanotechnology in Drug Delivery

Application of Nanotechnology in Drug Delivery Book
Author : Ali Demir Sezer
Publisher : BoD – Books on Demand
Release : 2014-07-25
ISBN : 9535116282
Language : En, Es, Fr & De

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Book Description :

This book collects reviews and original articles from eminent experts working in the interdisciplinary arena of nanotechnology use in drug delivery. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of nanotechnology application of drug delivery. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, pulmonary, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.

Advances in Micro Nano Electromechanical Systems and Fabrication Technologies

Advances in Micro Nano Electromechanical Systems and Fabrication Technologies Book
Author : Kenichi Takahata
Publisher : BoD – Books on Demand
Release : 2013-05-29
ISBN : 9535110853
Language : En, Es, Fr & De

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Book Description :

MEMS technology is increasingly penetrating into our lives and improving our quality of life. In parallel to this, advances in nanotechnology and nanomaterials have been catalyzing the rise of NEMS. Consisting of nine chapters reviewing state-of-the-art technologies and their future trends, this book focuses on the latest development of devices and fabrication processes in the field of these extremely miniaturized electromechanical systems. The book offers new knowledge and insight into design, fabrication, and packaging, as well as solutions in these aspects for targeted applications, aiming to support scientists, engineers and academic trainees who are engaged in relevant research. In the chapters, practical issues and advances are discussed for flexible microdevices, bioMEMS, intelligent implants, optical MEMS, nanomachined structures and NEMS, and others. Most of the chapters also focus on novel fabrication/packaging processes, including silicon bulk micromachining, laser micromachining, nanolithography, and packaging for implantable microelectronics enabled by nanomaterials.

New Scientist

New Scientist Book
Author : Anonim
Publisher : Unknown
Release : 2002
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download New Scientist book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.