Skip to main content

Medicinal Chemistry Of Anticancer Drugs

In Order to Read Online or Download Medicinal Chemistry Of Anticancer Drugs Full eBooks in PDF, EPUB, Tuebl and Mobi you need to create a Free account. Get any books you like and read everywhere you want. Fast Download Speed ~ Commercial & Ad Free. We cannot guarantee that every book is in the library!

Medicinal Chemistry of Anticancer Drugs

Medicinal Chemistry of Anticancer Drugs Book
Author : Carmen Avendano,J. Carlos Menendez
Publisher : Elsevier
Release : 2008-06-04
ISBN : 9780080559629
Language : En, Es, Fr & De

GET BOOK

Book Description :

Antitumor chemotherapy is nowadays a very active field of research, and a huge amount of information on the topic is generated every year. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book addresses the need for an updated treatment from the point of view of medicinal chemistry and drug design. The focus of Medicinal Chemistry of Anticancer Drugs is on the mechanism of action of antitumor drugs from the molecular point of view and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents, aiming at the rationalization of the action of this type of drug, which would allow the design of new active structures. * Explains the biological basis of cancer treatment and the role of chemists in improving anticancer drugs * Provides the historical background and serves as a comprehensive and practical guide on cancer research and anticancer drug development * Includes coverage of different approaches to treating cancer, drug resistance, and a chapter on cancer prevention

Medicinal Chemistry of Anticancer Drugs

Medicinal Chemistry of Anticancer Drugs Book
Author : Carmen Avendano,J. Carlos Menendez
Publisher : Elsevier
Release : 2015-06-11
ISBN : 0444626670
Language : En, Es, Fr & De

GET BOOK

Book Description :

Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design. Presents information in a clear and concise way using a large number of figures Historical background provides insights on how the process of drug discovery in the anticancer field has evolved Extensive references to primary literature

Advances in Anticancer Agents in Medicinal Chemistry

Advances in Anticancer Agents in Medicinal Chemistry Book
Author : Michelle Prudhomme
Publisher : Bentham Science Publishers
Release : 2013-06-14
ISBN : 1608054969
Language : En, Es, Fr & De

GET BOOK

Book Description :

Advances in Anticancer Agents in Medicinal Chemistry is an exciting eBook series comprising a selection of updated articles previously published in the peer-reviewed journal Anti-Cancer Agents in Medicinal Chemistry. The second Volume of this eBook series gathers updated reviews on several classes of molecules exhibiting anticarcinogenic potential as well as some important targets for the development of novel anticancer drugs.

The Anticancer Drugs

The Anticancer Drugs Book
Author : William B. Pratt,William D. Ensminger,Raymond W. Ruddon
Publisher : Oxford University Press, USA
Release : 1994
ISBN : 9780195067392
Language : En, Es, Fr & De

GET BOOK

Book Description :

This is an up-to-date review of the pharmacology, mechanisms of action, development of resistance, and toxicity of cancer chemotherapeutic agents. A rationale for their clinical use, based on cancer cell biology, is given for each class of drugs.

Medicinal Chemistry

Medicinal Chemistry Book
Author : Sriram
Publisher : Pearson Education India
Release : 2007
ISBN : 9788131700310
Language : En, Es, Fr & De

GET BOOK

Book Description :

Metal based Anticancer Agents

Metal based Anticancer Agents Book
Author : Angela Casini,Anne Vessières,Samuel M Meier-Menches
Publisher : Royal Society of Chemistry
Release : 2019-04-23
ISBN : 1788014065
Language : En, Es, Fr & De

GET BOOK

Book Description :

Metal-based anticancer drugs are among the most successful therapeutic agents, as evidenced by the frequent prescription of selected platinum and arsenic compounds to patients. Metal-based Anticancer Agents covers the interdisciplinary world of inorganic drug discovery and development by introducing the most prominent compound classes based on different transition metals, discussing emerging concepts and enabling methods, as well as presenting key pre-clinical and clinical aspects. Recent progress on the unique features of next-generation targeted metal-based anticancer agents, including supramolecular coordination complexes used for both therapy and drug delivery, promise a bright future beyond the benefits of pure cytotoxic activity. With contributions from global leaders in the field, this book will serve as a useful reference to established researchers as well as a practical guide to those new to metallodrugs, and postgraduate students of medicinal chemistry and metallobiology.

Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes

Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes Book
Author : Franco Cataldo,Tatiana da Ros
Publisher : Springer Science & Business Media
Release : 2008-09-08
ISBN : 140206845X
Language : En, Es, Fr & De

GET BOOK

Book Description :

Fullerenes and nanotubes are two classes of carbon structures or allotropes, which were discovered about 17 years ago. Since that time, many chemical derivatives have been synthesized using fullerenes and nanotubes as building blocks. Particularly promising was the theory that the chemical properties of fullerenes, and certain derivatives, made them likely candidates for anticancer drugs, inhibitors of viruses such as HIV, or even as anti-bacterials. Their cyctotoxicity can also be controlled by specific circumstances. In addition, the funtionalization of nanotubes has not only produced relatively simple derivatives, but also complex hybrids with biological macromolecules, which show unique supramolecular architecture and which are promising in many medical applications. The application of fullerenes and nanotubes in medicine is at the frontier of our knowledge, thus the work in this field represents the basis for future novel developments.

Chemistry and Pharmacology of Anticancer Drugs Second Edition

Chemistry and Pharmacology of Anticancer Drugs  Second Edition Book
Author : David E. Thurston,Ilona Pysz
Publisher : CRC Press
Release : 2019-07-07
ISBN : 9781138323582
Language : En, Es, Fr & De

GET BOOK

Book Description :

Bringing together a broad spectrum of information relating to the chemistry and pharmacology of anticancer drugs and therapies, this book covers the complete range of anticancer drug families and the chemical structures of all anticancer agents in clinical use, many at the research or clinical evaluation stage. The second edition features a new chapter on the quest for selectivity, which has become increasingly important in developing targeted drugs, that includes a table of all therapeutic classes along with their benefits and challenges. The text provides up-to-date information on biomarkers, pharmacogenetics and pharmacogenomics as well as agents used in the palliative care of cancer patients.

An Introduction to Medicinal Chemistry

An Introduction to Medicinal Chemistry Book
Author : Graham L. Patrick
Publisher : Oxford University Press
Release : 2013-01-10
ISBN : 0199697396
Language : En, Es, Fr & De

GET BOOK

Book Description :

This volume provides an introduction to medicinal chemistry. It covers basic principles and background, and describes the general tactics and strategies involved in developing an effective drug.

Bioinorganic Medicinal Chemistry

Bioinorganic Medicinal Chemistry Book
Author : Enzo Alessio
Publisher : John Wiley & Sons
Release : 2011-02-25
ISBN : 352763312X
Language : En, Es, Fr & De

GET BOOK

Book Description :

This book gives a comprehensive overview about medicinal inorganic chemistry. Topics like targeting strategies, mechanism of action, Pt-based antitumor drugs, radiopharmaceuticals are covered in detail and offer the reader an in-depth overview about this important topic.

Frontiers in Anti Cancer Drug Discovery Volume 1

Frontiers in Anti Cancer Drug Discovery  Volume  1  Book
Author : Atta-ur- Rahman,M. Iqbal Choudhary
Publisher : Bentham Science Publishers
Release : 2011-02-14
ISBN : 1608051617
Language : En, Es, Fr & De

GET BOOK

Book Description :

"Frontiers in Anti-Cancer Drug Discovery" is an Ebook series devoted to publishing the latest and the most important advances in Anti-Cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug di

Medicinal Chemistry

Medicinal Chemistry Book
Author : Thomas Nogrady,Donald F. Weaver
Publisher : Oxford University Press
Release : 2005-08-11
ISBN : 9780195104554
Language : En, Es, Fr & De

GET BOOK

Book Description :

Fully updated, this textbook takes a receptor-based, target-centred approach, presenting concepts central to the study of drug action in a logical, mechanistic way, grounded on molecular & biochemical principles.

Frontiers in Anti Cancer Drug Discovery

Frontiers in Anti Cancer Drug Discovery Book
Author : Atta-ur-Rahman,M. Iqbal Choudhary
Publisher : Bentham Science Publishers
Release : 2013-11-29
ISBN : 1608058085
Language : En, Es, Fr & De

GET BOOK

Book Description :

Frontiers in Anti-Cancer Drug Discovery is an Ebook series devoted to publishing the latest and the most important advances in Anti-Cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The Ebook series should prove to be of interest to all pharmaceutical scientists involved in research in Anti-Cancer drug design and discovery. Each volume is devoted to the major advances in Anti-Cancer drug design and discovery. The Ebook series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

Green Approaches in Medicinal Chemistry for Sustainable Drug Design

Green Approaches in Medicinal Chemistry for Sustainable Drug Design Book
Author : Bimal K. Banik
Publisher : Advances in Green Chemistry
Release : 2020-04
ISBN : 0128175923
Language : En, Es, Fr & De

GET BOOK

Book Description :

Extensive experimentation and high failure rates are a well-recognised downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry reveals how medicinal and green chemistry can work together to directly address this issue. After providing essential context to the growth of green chemistry in relation to drug discovery in Part 1, the book goes on to identify a broad range of practical methods and synthesis techniques in Part 2. Part 3 reveals how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process, whilst Parts 4 and 5 discuss natural products and microwave-induced chemistry. Finally, the role of computers in drug discovery is explored in Part 6.

Introduction to Medicinal Chemistry

Introduction to Medicinal Chemistry Book
Author : Alex Gringauz
Publisher : Wiley-VCH
Release : 1997
ISBN :
Language : En, Es, Fr & De

GET BOOK

Book Description :

This work brigdges the compartmentalized undergraduate organic and biochemistry and biology subjects to the pharmacology and the clinical areas a modern pharmacy practice requires. The changes and constantly increasing responsibilities of today's pharmacist have dictated a restructuring of the pharmacy curriculum, including individual course content. This book reflects and addresses these developments. This is a well-written work that covers most major areas of pharmaceutical research. The text is presented in a logical and concise fashion being divided into chapters based upon therapeutic topic. This makes the work very useful for teaching a course in medicinal chemistry since therapeutic areas can be separately covered without having to make use of the entire book which overall contains a tremendous amount of information. This book is a significant contribution to understanding what medicinal chemistry is and how this science is used to develop new therapeutic agents.

Natural Products in Medicinal Chemistry

Natural Products in Medicinal Chemistry Book
Author : Stephen Hanessian
Publisher : John Wiley & Sons
Release : 2013-12-18
ISBN : 3527676562
Language : En, Es, Fr & De

GET BOOK

Book Description :

The inspiration provided by biologically active natural products to conceive of hybrids, congeners, analogs and unnatural variants is discussed by experts in the field in 16 highly informative chapters. Using well-documented studies over the past decade, this timely monograph demonstrates the current importance and future potential of natural products as starting points for the development of new drugs with improved properties over their progenitors. The examples are chosen so as to represent a wide range of natural products with therapeutic relevance among others, as anticancer agents, antimicrobials, antifungals, antisense nucleosides, antidiabetics, and analgesics. From the content: * Part I: Natural Products as Sources of Potential Drugs and Systematic Compound Collections * Part II: From Marketed Drugs to Designed Analogs and Clinical Candidates * Part III: Natural Products as an Incentive for Enabling Technologies * Part IV: Natural Products as Pharmacological Tools * Part V: Nature: The Provider, the Enticer, and the Healer

Medicinal Chemistry

Medicinal Chemistry Book
Author : Th Nogrady,Donald F. Weaver
Publisher : Oxford University Press
Release : 2005
ISBN : 0195104560
Language : En, Es, Fr & De

GET BOOK

Book Description :

Fully updated, the third edition of this popular textbook remains comprehensive, authoritatives and readable. Taking a receptor-based, target-centred approach, it presents the concepts central to the study of drug action in a logical, mechanistic way grounded on molecular and biochemical principles. The changes in this edition have been many and varied, including a new chapter on the immune system, updated discussions of molecular modelling techniques, and new clinical-molecular interface sections that facilitate understanding of the treatment of human disease at a molecular level. This book is designed for students of pharmacy, chemistry, and pharmacology.

The Search for New Anticancer Drugs

The Search for New Anticancer Drugs Book
Author : Michael Waring,B.A. Ponder
Publisher : Springer Science & Business Media
Release : 1992-11-30
ISBN : 9780792389590
Language : En, Es, Fr & De

GET BOOK

Book Description :

Most of the anti-cancer drugs in use today were discovered by happy accident rather than design, yet the rational design of better anti-cancer drugs remains a cherished goal, and one of the most important challenges facing medical science. This book represents a compilation of views and progress reports which illustrate the diversity of approaches to the problem. Recent research has confirmed the belief that critical genetic changes are at work in cancer cells. The genome, then (DNA in biochemical terms), surely represents a critical target for specific chemotherapy of cancer, and several chapters address the issue of attacking DNA, gene targetting, and the like. Others deal with principles of rational design, exploitation of novel modalities and targets, or the nuts and bolts of antitumour drug testing. While no attempt has been made to provide a comprehensive coverage of this wide-ranging and vitally important subject, the present volume in the series will provide much food for thought.