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Mechanotransduction Cell Signaling To Cell Response

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Mechanotransduction

Mechanotransduction Book
Author : Paul A. Sundaram
Publisher : Academic Press
Release : 2020-11-18
ISBN : 0128178833
Language : En, Es, Fr & De

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Book Description :

Mechanotransduction: Cell Signaling to Cell Response covers the cell machinery responsible for the process of mechanotransduction and the manner in which cells respond to an external mechanical stimulus. The effect of mechanical stimulus on individual cells and entire tissues is discussed, with an emphasis on the practical results of this physiological process. Mechanotransduction of stem cells and cancerous cells are also covered, along with future directions in this yet nascent field. This book gives insights on basic processes that occur (or may occur) in the human body as a result of the application of mechanical stimulus. It is ideal for both biomedical engineers and biologists, and is an ideal resource for teaching. It provides a current state of conceptual and practical aspects of the field and will enable students and professionals to venture further into this incipient area which is of fundamental importance to biomedical engineering and biology fields. Covers fundamental concepts of signaling in cells as a result of mechanical stimulus Includes the physiological results of mechanical stimulus on the human body Explores the advantages of mechanical loads on the human body

Mechanotransduction

Mechanotransduction Book
Author : Anonim
Publisher : Academic Press
Release : 2014-07-29
ISBN : 0123983274
Language : En, Es, Fr & De

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Book Description :

Progress in Molecular Biology and Translational Science provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology. It contains contributions from leaders in their fields and abundant references. Volume 126 features in-depth reviews that focus on the tools required to investigate mechanotransduction. Additional chapters focus on how we can use these tools to answer fundamental questions about the interaction of physical forces with cell biology, morphogenesis, and function of mature structures. Chapters in the volume are authored by a unique combination of cell biologists and engineers, providing a range of perspectives on mechanotransduction. Provides a unique combination of perspectives from biologists and engineers Engaging to people of many training backgrounds

Orthodontics E Book

Orthodontics   E Book Book
Author : Lee W. Graber,Robert L. Vanarsdall,Katherine W. L. Vig,Greg J. Huang
Publisher : Elsevier Health Sciences
Release : 2016-07-15
ISBN : 0323444326
Language : En, Es, Fr & De

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Book Description :

Comprehensive, cutting-edge content prepares you for today’s orthodontics! Orthodontics: Current Principles and Techniques, 6th Edition provides evidence-based coverage of orthodontic diagnosis, planning strategies, and treatment protocols, including esthetics, genetics, temporary anchorage devices, aligners, technology-assisted biomechanics, and much more. New to this edition is an Expert Consult website using videos and additional visuals to show concepts difficult to explain with words alone. Expert Consult also adds three online-only chapters, research updates, and a fully searchable version of the text. From respected editors Lee Graber, Robert Vanarsdall, Katherine Vig, and Greg Huang, along with a veritable Who’s Who of expert contributors, this classic reference has a concise, no-nonsense approach to treatment that makes it the go-to book for orthodontic residents and practitioners! Comprehensive coverage provides a one-stop resource for the field of orthodontics, including foundational theory and the latest on the materials and techniques used in today’s practice. Experienced, renowned editors lead a team of expert, international contributors, bringing the most authoritative clinical practice and supporting science from the best and brightest in the industry. More than 3,400 images include a mixture of radiographs, full-color clinical photos, and anatomic or schematic line drawings, showing examples of treatment, techniques, and outcomes. Extensive references make it easy to look up the latest in orthodontic research and evidence-based information, and all references also appear online. Detailed, illustrated case studies show the decision-making process, showing the consequences of various treatment techniques over time. NEW! Seven all-new chapters include Orthodontic Diagnosis and Treatment Planning with Cone-Beam Computed Tomography Imaging; Upper Airway, Cranial Morphology, and Sleep Apnea; Management of Impactions; Iatrogenic Effects of Orthodontic Appliances; Minimally and Non-Invasive Approaches to Accelerate Tooth Movement; Management of Dental Luxation and Avulsion Injuries in the Permanent Dentition; and Patient Management and Motivation for the Child and Adolescent Patient. NEW! Expert Consult website includes online-only chapters, instructional videos, many references linked to PubMed, and research updates including additional case studies. UPDATED CHAPTERS include Biomechanical Considerations with Temporary Anchorage Devices, Bonding in Orthodontics, Clear Aligner Treatment, Lingual Appliance Treatment, Psychological Aspects of Diagnosis and Treatment, Clinically Relevant Aspects of Dental Materials Science in Orthodontics, The Biologic Basis of Orthodontics, and more. New co-editor Greg J. Huang is joined by new contributors who are highly regarded experts within their respective subspecialties in orthodontics.

Orthodontics Diagnosis of Management of Malocclusion Dentofacial Deformities E Book

Orthodontics  Diagnosis of   Management of Malocclusion   Dentofacial Deformities   E Book Book
Author : Om Prakash Kharbanda
Publisher : Elsevier Health Sciences
Release : 2019-12-04
ISBN : 8131249360
Language : En, Es, Fr & De

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Book Description :

The second edition is expanded and rejuvenated with a greater focus on PG students, orthodontic educators, UG students and practitioners. The book covers entire panorama of science and clinical practice of orthodontics, from basics to clinical, presented in 58 chapters organised in 15 sections. The information is provided in-depth, literature supported, complimented with real life scenarios and case reports. A special effort has been made to include structured information on subjects of relevance which are much talked about but found only in journals. Contains a balanced blend of texts, graphics, boxes and clinical case reports encountered in clinical practice A comprehensive coverage of cephalometric radiology, ethnic norms and advances in three-dimensional imaging A detailed step by step approach to orthodontic treatment with contemporary fixed appliances, from diagnosis to finishing Provides an up-to-date information on topics of day-to-day relevance such as epidemiology of malocclusion and orthodontic indices, psychological aspects of orthodontics, debonding, care and maintenance of occlusion after orthodontic treatment Presents updated information on temporary anchorage devices (TAD), impacted and transposed teeth, inter-disciplinary treatment, management of cleft lip and palate and orthognathic surgery Emerging fields such as surgically facilitated rapid tooth movement, distraction osteogenesis and obstructive sleep apnoea (OSA) are included with up-to-date clinically relevant information Includes Companion Website containing procedural videos

Cell Signaling in Vascular Inflammation

Cell Signaling in Vascular Inflammation Book
Author : Jahar Bhattacharya
Publisher : Springer Science & Business Media
Release : 2007-11-15
ISBN : 1592599095
Language : En, Es, Fr & De

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Book Description :

A comprehensive survey by leading basic and clinical researchers of the signal transduction mechanisms responsible for lung inflammation, including vascular hyperpermeability, white cell accumulation, and vascular remodeling. The authors cut across disciplines to bring together a broad-based presentation of inflammatory challenge, both in the initial phases of the inflammatory response, as well as in the more prolonged phase of genomic involvement. The book illuminates not only the processes of lung inflammation, but also the potential for developing new therapeutic strategies to combat inflammatory lung disease.

Mechanosensitive Ion Channels

Mechanosensitive Ion Channels Book
Author : Andre Kamkin,Irina Kiseleva
Publisher : Springer Science & Business Media
Release : 2007-10-06
ISBN : 1402064268
Language : En, Es, Fr & De

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Book Description :

This book explores the latest data dealing with mechanosensitive channels research results. It was compiled by a group of internationally recognized scientists leading in the field of mechanosensitive ion channels or mechanically gated channels and signaling cascades research. Key problems of cell mechanobiology are also discussed. As a whole, the volume dwells on the major issues of mechanical stress influencing the ion channels and intracellular signaling pathways.

Rheumatology E Book

Rheumatology E Book Book
Author : Marc C. Hochberg,Alan J. Silman,Josef S. Smolen,Michael E. Weinblatt,Michael H. Weisman
Publisher : Elsevier Health Sciences
Release : 2014-06-24
ISBN : 0702063037
Language : En, Es, Fr & De

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Book Description :

Stay current in the ever-changing discipline of rheumatology with clear, reliable guidance from Hochberg’s Rheumatology, one of the most respected and trusted sources in the field. Designed to meet the needs of the practicing clinician, this medical reference book provides extensive, authoritative coverage of rheumatic diseases from basic scientific principles to practical points of clinical management in a lucid, logical, user-friendly manner. Track disease progression and treat patients more effectively with the information on genetic findings, imaging outcomes, cell and biologic therapies, rheumatoid arthritis, and SLE. Incorporate recent findings about pathogenesis of disease; imaging outcomes for specific diseases like RA, osteoarthritis, and spondyloarthropathies; cell and biologic therapies; and other timely topics. Remain up to date on the latest information in rheumatology through 13 brand-new chapters covering biomedical and translation science, disease and outcome assessment, new imaging modalities, early emerging disease, clinical therapeutics, patient management, and rehabilitation. Take advantage of expanded coverage of small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies. Focus on the core knowledge needed for successful results with each chapter co-authored by an internationally-renowned specialist in the field. Easily find the information you need thanks to a consistent, user-friendly format with templated content and large-scale images.

Handbook of Imaging in Biological Mechanics

Handbook of Imaging in Biological Mechanics Book
Author : Corey P. Neu,Guy M. Genin
Publisher : CRC Press
Release : 2014-10-24
ISBN : 1466588144
Language : En, Es, Fr & De

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Book Description :

Emerging imaging techniques have opened new fronts to investigate tissues, cells, and proteins. Transformative technologies such as microCT scans, super-resolution microscopy, fluorescence-based tools, and other methods now allow us to study the mechanics of cancer, dissect the origins of cellular force regulation, and examine biological specimens

Local Flaps in Facial Reconstruction E Book

Local Flaps in Facial Reconstruction E Book Book
Author : Shan R. Baker
Publisher : Elsevier Health Sciences
Release : 2014-02-25
ISBN : 0323262058
Language : En, Es, Fr & De

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Book Description :

Local Flaps in Facial Reconstruction brings you the detailed visual guidance and unmatched expertise you need to achieve the best results for the full range of facial flap procedures. Full-color clinical photographs and line drawings—along with high-quality surgical video clips—capture the latest facial reconstruction practices and effective methods like reconstruction of skin defects on the head and neck following tumor removal or trauma. Perspectives from facial plastic surgeons, dermatologists, ophthalmologists, and otolaryngologists help you take all of these considerations into account in treatment planning. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Make the most effective clinical decisions with a better understanding of the anatomy, physiology, and biomechanics of the skin Understand skin flap anatomy and physiology—vital to the performance of successful local flap reconstruction for facial defects. Implement the latest techniques with updated coverage of new wound closure techniques and materials (including glues and adhesives), scar revision, complications, and vascular abnormalities. Watch clips of key surgical procedures, including reconstructive surgery of the nose and lip. Avoid pitfalls and achieve the best outcomes thanks to a step-by-step approach to each procedure, complete with tips and tricks of the trade from leading experts. Minimize flap ischemia and other complications with proper preoperative planning and surgical techniques. Visualize what to look for and how to proceed with high-quality illustrations of rotation flaps, transposition flaps, advancement flaps, bilobe flaps, melolabial flaps, paramedian forehead flaps, and rhombic flaps. Access video clips at Expert Consult.

Mechanobiology of Cell Cell and Cell Matrix Interactions

Mechanobiology of Cell Cell and Cell Matrix Interactions Book
Author : A. Wagoner Johnson,Brendan Harley
Publisher : Springer Science & Business Media
Release : 2011-02-21
ISBN : 9781441980830
Language : En, Es, Fr & De

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Book Description :

Mechanobiology of Cell-Matrix Interactions focuses on characterization and modeling of interactions between cells and their local extracellular environment, exploring how these interactions may mediate cell behavior. Studies of cell-matrix interactions rely on integrating engineering, (molecular and cellular) biology, and imaging disciplines. Recent advances in the field have begun to unravel our understanding of how cells gather information from their surrounding environment, and how they interrogate such information during the cell fate decision making process. Topics include adhesive and integrin-ligand interactions; extracellular influences on cell biology and behavior; cooperative mechanisms of cell-cell and cell-matrix interactions; the mechanobiology of pathological processes; (multi-scale) modeling approaches to describe the complexity or cell-matrix interactions; and quantitative methods required for such experimental and modeling studies.

Vascular Endothelium

Vascular Endothelium Book
Author : John D. Catravas,Allan D. Callow,Una S. Ryan
Publisher : IOS Press
Release : 1999
ISBN : 9789051994438
Language : En, Es, Fr & De

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Book Description :

With its innovative topical approach, bestselling COMPARATIVE CRIMINAL JUSTICE SYSTEMS, 5e offers a comprehensive analysis as it compares the various criminal justice systems throughout the world using six model countries: China, England, France, Germany, Japan, and Saudi Arabia. The text illustrates the different types of law and justice systems while exploring the historical, political, economic, social, and cultural influences on each system. This unique approach examines important aspects of each type of justice system--common law, civil law, socialist law, and sacred (Islamic) law--to give students a thorough understanding of the similarities and differences of each system without overloading them with too much information. Completely up to date, the Fifth Edition includes the latest trends and issues in international juvenile justice, policing, and terrorism, including expanded coverage of such high- profile topics as human trafficking, Internet pornography, identity theft, transnational policing, and more.

The Mechanotransduction Response of Tendon Cells to Tensile Loading

The Mechanotransduction Response of Tendon Cells to Tensile Loading Book
Author : Michael Lavagnino
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Mechanotransduction Response of Tendon Cells to Tensile Loading book written by Michael Lavagnino, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Cardiac Mechanotransduction

Cardiac Mechanotransduction Book
Author : Matti Weckström,Pasi Tavi
Publisher : Springer Science & Business Media
Release : 2007-12-22
ISBN : 9780387488684
Language : En, Es, Fr & De

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Book Description :

This book presents a multidisciplinary approach to cardiac mechanotransduction. The chapters depict the many faces of the topic, from membrane and ion channel level to mechanics, biochemical signaling and regulation via hormone systems. Cardiac Mechanotransduction is of interest to basic life sciences, like physiology, biochemistry and pharmacology, but also to clinicians working with heart-related problems, such as cardiologists and internists.

Mechanosensitivity and Mechanotransduction

Mechanosensitivity and Mechanotransduction Book
Author : Irina Kiseleva,Andre Kamkin
Publisher : Springer Science & Business Media
Release : 2010-11-18
ISBN : 9789048198818
Language : En, Es, Fr & De

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Book Description :

This book presents the latest findings in the field of research of mechanosensitivity and mechanotransduction in different cells and tissues. Mechanosensitivity and mechanotransduction of the heart and vascular cells, in the lung, in bone and joint tissues, in sensor systems and in blood cells are described in detail. This Volume focuses on molecular mechanisms of mechanosensitivity and mechanotransduction via cytoskeleton. Integrin-mediated mechanotransduction, the role of actin cytoskeleton and the role of other cytoskeletal elements are discussed. It contains a detailed description of several stretch-induced signaling cascades with multiple levels of crosstalk between different pathways. It contains a description of the role of nitric oxide in regulation of cardiac activity and in regulation of mechanically gated channels in the heart. In the heart mechanical signals are propagated into the intracellular space primarily via integrin-linked complexes, and are subsequently transmitted from cell to cell via paracrine signaling. Biochemical signals derived from mechanical stimuli activate both acute phosphorylation of signaling cascades, such as in the PI3K, FAK, and ILK pathways, and long-term morphological modii cations via intracellular cytoskeletal reorganization and extracellular matrix remodelling. Cellular and molecular effects of mechanical stretch on vascular cells are also discussed. This Volume highlights the role of mechanotransduction in the lung, in bone and joint tissues. For the first time mechanosensitivity and mechanotransduction in blood cells are discussed. It contains new insights into mechanosensitive K+ channels functioning in mouse B lymphocytes. This book is a unique collection of reviews outlining current knowledge and future developments in this rapidly growing field. Currently, investigations of the molecular mechanisms of mechanosensitivity and mechanotransduction are focused on several issues. The majority of studies investigate intracellular signaling pathways. Knowledge of the mechanisms which underlie these processes is necessary for understanding of the normal functioning of different organs and tissues and allows to predict changes, which arise due to alterations of their environment. Possibly such knowledge will allow the development of new methods of artificial intervention and therapies. This book brings up the problem closer to the experts in related medical and biological sciences as well as practicing doctors besides just presenting the latest achievements in the field.

Tissue Engineering

Tissue Engineering Book
Author : John P. Fisher,Antonios G. Mikos,Joseph D. Bronzino,Donald R. Peterson
Publisher : CRC Press
Release : 2012-12-11
ISBN : 1439874034
Language : En, Es, Fr & De

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Book Description :

Tissue engineering research continues to captivate the interest of researchers and the general public alike. Popular media outlets like The New York Times, Time, and Wired continue to engage a wide audience and foster excitement for the field as regenerative medicine inches toward becoming a clinical reality. Putting the numerous advances in the fi

Introduction to Cell Mechanics and Mechanobiology

Introduction to Cell Mechanics and Mechanobiology Book
Author : Christopher R. Jacobs,Hayden Huang,Ronald Y. Kwon
Publisher : Garland Pub
Release : 2013
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

"Introduction to Cell Mechanics and Mechanobiology teaches advanced undergraduate students a quantitative understanding of the way cells detect, modify, and respond to the physical properties within the cell environment. Coverage includes the mechanics of single molecule polymers, polymer networks, two-dimensional membranes, whole-cell mechanics, and mechanobiology, as well as primer chapters on solid, fluid, and statistical mechanics"--Provided by publisher.

PCR Technology

PCR Technology Book
Author : Tania Nolan,Stephen A. Bustin
Publisher : CRC Press
Release : 2013-06-13
ISBN : 143984805X
Language : En, Es, Fr & De

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Book Description :

PCR’s simplicity as a molecular technique is, in some ways, responsible for the huge amount of innovation that surrounds it, as researchers continually think of new ways to tweak, adapt, and re-formulate concepts and applications. PCR Technology: Current Innovations, Third Edition is a collection of novel methods, insights, and points of view that provides a critical and timely reference point for anyone wishing to use this technology. Topics in this forward-thinking volume include: The purification and handling of PCR templates The effect of the manufacture and purification of the oligonucleotide on PCR behavior Optimum buffer composition Probe options The design and optimization of qPCR assays Issues surrounding the development and refinement of instrumentation Effective controls to protect against uncertainties due to reaction variability Covering all aspects of PCR and real-time PCR, the book contains detailed protocols that make it suitable as both a reference and an instruction manual. Each chapter presents detailed guidelines as well as helpful hints and tips supplied by authors who are recognized experts in their fields. In addition to descriptions of current technology and best practices, the book also provides information about new developments in the PCR arena.

Static Equibiaxial Stretch Mediated Mechanotransduction in Adult Cardiac Fibroblasts

Static Equibiaxial Stretch Mediated Mechanotransduction in Adult Cardiac Fibroblasts Book
Author : Sonya Renee Summerour
Publisher : Unknown
Release : 1999
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Static Equibiaxial Stretch Mediated Mechanotransduction in Adult Cardiac Fibroblasts book written by Sonya Renee Summerour, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Mesenchymal Cell Activation by Biomechanical Stimulation and its Clinical Prospects

Mesenchymal Cell Activation by Biomechanical Stimulation and its Clinical Prospects Book
Author : Nahum Rosenberg
Publisher : Bentham Science Publishers
Release : 2016-03-04
ISBN : 1681081997
Language : En, Es, Fr & De

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Book Description :

The electrical response of cells to mechanical stimulus is known as mechanotransduction. This monograph is a summary of the mechanotransduction in musculoskeletal cells responsible for body tissue maintenance, support, cover and movement. While mechanotransduction is similar among these cells, there are also several important differences in mechanical parameters and cellular pathways characteristic to each cell type. Therefore, readers will have the opportunity to update their knowledge about the increasing volume of information on mechanotransduction in these cells gained from current research. The book features a primer on general aspects of cellular biomechanics and the experimental methods and equipment commonly used for investigating cellular mechanotransduction in vitro in two dimensional cultures in which cells are adherent to plastic surfaces. Characteristic mechanotransduction pathways in mesenchymal stem cells (MSCs), chondrocytes, osteoblasts and fibroblasts are described in the accompanying chapters. Finally, a description of clinical implementation of mechanical stimulation is presented with emphasis on distraction osteogenesis, involving osteoblast stimulation, and skin stretching techniques based on fibroblast stimulation. This monograph is a useful reference for readers involved in graduate courses or basic research in cell biology and musculoskeletal physiology.

Comprehensive Biomaterials

Comprehensive Biomaterials Book
Author : Paul Ducheyne,Kevin Healy,Dietmar W. Hutmacher,David W. Grainger,C. James Kirkpatrick
Publisher : Elsevier
Release : 2015-08-28
ISBN : 0080552943
Language : En, Es, Fr & De

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Book Description :

Comprehensive Biomaterials brings together the myriad facets of biomaterials into one, major series of six edited volumes that would cover the field of biomaterials in a major, extensive fashion: Volume 1: Metallic, Ceramic and Polymeric Biomaterials Volume 2: Biologically Inspired and Biomolecular Materials Volume 3: Methods of Analysis Volume 4: Biocompatibility, Surface Engineering, and Delivery Of Drugs, Genes and Other Molecules Volume 5: Tissue and Organ Engineering Volume 6: Biomaterials and Clinical Use Experts from around the world in hundreds of related biomaterials areas have contributed to this publication, resulting in a continuum of rich information appropriate for many audiences. The work addresses the current status of nearly all biomaterials in the field, their strengths and weaknesses, their future prospects, appropriate analytical methods and testing, device applications and performance, emerging candidate materials as competitors and disruptive technologies, and strategic insights for those entering and operational in diverse biomaterials applications, research and development, regulatory management, and commercial aspects. From the outset, the goal was to review materials in the context of medical devices and tissue properties, biocompatibility and surface analysis, tissue engineering and controlled release. It was also the intent both, to focus on material properties from the perspectives of therapeutic and diagnostic use, and to address questions relevant to state-of-the-art research endeavors. Reviews the current status of nearly all biomaterials in the field by analyzing their strengths and weaknesses, performance as well as future prospects Presents appropriate analytical methods and testing procedures in addition to potential device applications Provides strategic insights for those working on diverse application areas such as R&D, regulatory management, and commercial development