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Mass Spectrometry

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Mass Spectrometry

Mass Spectrometry Book
Author : Jürgen H Gross
Publisher : Springer Science & Business Media
Release : 2006-04-05
ISBN : 3540407391
Language : En, Es, Fr & De

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Book Description :

Mass Spectrometry is an ideal textbook for students and professionals as well as newcomers to the field. Starting from the very first principles of gas-phase ion chemistry and isotopic properties, the textbook takes the reader through the design of mass analyzers and ionization methods all the way to mass spectral interpretation and coupling techniques. Step-by-step, the reader learns how mass spectrometry works and what it can do. The book comprises a balanced mixture of practice-oriented information and theoretical background. It features a clear layout and a wealth of high-quality figures. Exercises and solutions are located on the Springer Global Web.

Mass Spectrometry

Mass Spectrometry Book
Author : Edmond de Hoffmann,Vincent Stroobant
Publisher : John Wiley & Sons
Release : 2013-04-03
ISBN : 1118681940
Language : En, Es, Fr & De

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Book Description :

The latest edition of a highly successful textbook, MassSpectrometry, Third Edition provides students with a completeoverview of the principles, theories and key applications of modernmass spectrometry. All instrumental aspects of mass spectrometryare clearly and concisely described: sources, analysers anddetectors. Tandem mass spectrometry is introduced early on and thendeveloped in more detail in a later chapter. Emphasis is placedthroughout the text on optimal utilisation conditions. Variousfragmentation patterns are described together with analyticalinformation that derives from the mass spectra. This new edition has been thoroughly revised and updated and hasbeen redesigned to give the book a more contemporary look. As withprevious editions it contains numerous examples, references and aseries of exercises of increasing difficulty to encourage studentunderstanding. Updates include: Increased coverage of MALDI andESI, more detailed description of time of flight spectrometers, newmaterial on isotope ratio mass spectrometry, and an expanded rangeof applications. Mass Spectrometry, Third Edition is an invaluableresource for all undergraduate and postgraduate students using thistechnique in departments of chemistry, biochemistry, medicine,pharmacology, agriculture, material science and food science. It isalso of interest for researchers looking for an overview of thelatest techniques and developments.

Introduction to Mass Spectrometry

Introduction to Mass Spectrometry Book
Author : J. Throck Watson,O. David Sparkman
Publisher : John Wiley & Sons
Release : 2013-07-09
ISBN : 1118681584
Language : En, Es, Fr & De

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Book Description :

Completely revised and updated, this text provides an easy-to-read guide to the concept of mass spectrometry and demonstrates its potential and limitations. Written by internationally recognised experts and utilising "real life" examples of analyses and applications, the book presents real cases of qualitative and quantitative applications of mass spectrometry. Unlike other mass spectrometry texts, this comprehensive reference provides systematic descriptions of the various types of mass analysers and ionisation, along with corresponding strategies for interpretation of data. The book concludes with a comprehensive 3000 references. This multi-disciplined text covers the fundamentals as well as recent advance in this topic, providing need-to-know information for researchers in many disciplines including pharmaceutical, environmental and biomedical analysis who are utilizing mass spectrometry

Fundamentals of Mass Spectrometry

Fundamentals of Mass Spectrometry Book
Author : Kenzo Hiraoka
Publisher : Springer Science & Business Media
Release : 2013-06-13
ISBN : 1461472334
Language : En, Es, Fr & De

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Book Description :

Most research and all publications in mass spectrometry address either applications or practical questions of procedure. This book, in contrast, discusses the fundamentals of mass spectrometry. Since these basics (physics, chemistry, kinetics, and thermodynamics) were worked out in the 20th century, they are rarely addressed nowadays and young scientists have no opportunity to learn them. This book reviews a number of useful methods in mass spectrometry and explains not only the details of the methods but the theoretical underpinning.

Introductory Mass Spectrometry Second Edition

Introductory Mass Spectrometry  Second Edition Book
Author : Stephen Shrader
Publisher : CRC Press
Release : 2013-11-12
ISBN : 1466595841
Language : En, Es, Fr & De

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Book Description :

Mass spectrometry has played an integral part in the study of organic molecular structures for more than 50 years, offering significant information from small amounts of sample. The mass spectrum produced by electron impact ionization presents a pattern of peaks that can often give definitive structural information about an unknown compound. Introductory Mass Spectrometry, Second Edition guides readers in the understanding and recognition of those patterns, discussing mass spectra in terms that are familiar to chemists. It provides a basis for chemists to interpret mass spectra to solve particular structural problems. The Second Edition has been updated with modern techniques and data handling. Beginning with an introduction to the principles and instrumentation, it then sequentially explains the processes that occur in the mass spectrometer following ionization. The book is unique in the large number of mass spectra presented and provides examples of mass spectra from a wide variety of organic chemicals, concentrating on the relationships between fragmentation patterns, common chemical reactions, and chemical structures. The book also discusses mass spectra obtained with softer ionization techniques, which provide definitive information regarding molecular weights. The text describes mass spectra produced by electron ionization, discussing how the spectral peak pattern relates to molecular structure. It details the use of high-resolution and accurate mass measurement to determine elemental composition of ions in order to identify unknown substances. The book also introduces some of the recent techniques that can be employed to extend the usefulness of mass spectrometry to high molecular weight substances and more polar substances. It includes examples and problems representing a cross section of organic chemistry to help readers integrate the principles presented.

Mass Spectrometry Handbook

Mass Spectrometry Handbook Book
Author : Mike S. Lee
Publisher : John Wiley & Sons
Release : 2012-04-16
ISBN : 1118180720
Language : En, Es, Fr & De

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Book Description :

Due to its enormous sensitivity and ease of use, mass spectrometry has grown into the analytical tool of choice in most industries and areas of research. This unique reference provides an extensive library of methods used in mass spectrometry, covering applications of mass spectrometry in fields as diverse as drug discovery, environmental science, forensic science, clinical analysis, polymers, oil composition, doping, cellular research, semiconductor, ceramics, metals and alloys, and homeland security. The book provides the reader with a protocol for the technique described (including sampling methods) and explains why to use a particular method and not others. Essential for MS specialists working in industrial, environmental, and clinical fields.

Mass Spectrometry

Mass Spectrometry Book
Author : Michael A. Madson
Publisher : Elsevier
Release : 2016-05-06
ISBN : 0128041358
Language : En, Es, Fr & De

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Book Description :

Mass Spectrometry: Techniques for the Structural Characterization of Glycans presents new methods for conducting detailed carbohydrate qualitative analysis—arming analytical chemists, pharmaceutical scientists, and food scientists with a quick reference that will allow them to determine the structures of carbohydrates molecules. As there is a need in the scientific community for content specific to structural determination and analysis of new glycoprotein drug, and because structure-activity analysis requires a structural determination of the N- and O-linked oligosaccharides linked to glycol-proteins, this book provides the relevant research that are necessary for advances and new outcomes in this area of study. Authored by an analytical chemist with more than 30 years of experience in research and industry Serves as a quick reference in mass spectral analysis and carbohydrates Includes more than 60 figures to aid in the retention of key concepts

Advances in Mass Spectrometry

Advances in Mass Spectrometry Book
Author : R. M. Elliott
Publisher : Elsevier
Release : 2013-10-22
ISBN : 1483149447
Language : En, Es, Fr & De

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Book Description :

Advances in Mass Spectrometry, Volume 2 documents the proceedings of a conference on mass spectrometry held in Oxford in September 1961. This compilation is categorized into six major topics — mass spectrometry in research; mass spectrometry of inorganic compounds; instruments and techniques; theory and correlation of mass spectra; mass spectra and analysis; and ionization and dissociation. Under these major topics, parts of the papers discussed include field ionization mass spectroscopy; initial kinetic energy discrimination effects in crossed-field ion sources; mass spectrometric study of CaO and Ta; and spark source mass spectrometry as an analytical technique. The book also covers discussions on initial energy of hydrocarbon fragment ions; determination of the structure of alkaloids by mass spectrometry; and application of a time-of-flight mass spectrometer to the examination of ion-molecule interactions. This volume is a useful reference to students and researchers conducting work on mass spectrometry.

Ion Mobility Mass Spectrometry

Ion Mobility Mass Spectrometry Book
Author : Alison E Ashcroft,Frank Sobott
Publisher : Royal Society of Chemistry
Release : 2021-11-26
ISBN : 1839162899
Language : En, Es, Fr & De

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Book Description :

Over the last decade, the use of ion mobility separation in combination with mass spectrometry analysis has developed significantly. This technique adds a unique extra dimension enabling the in-depth analysis of a wide range of complex samples in the areas of the chemical and biological sciences. Providing a comprehensive guide to the technique, each chapter is written by an internationally recognised expert and with numerous different commercial platforms to choose from, this book will help the end users understand the practicalities of using different instruments for different ion mobility purposes. The first section provides a detailed account of the fundamentals behind the technique and the current range of available instrumentation. The second section focusses on the wide range of applications that have benefitted from ion mobility – mass spectrometry and includes topics taken from current research in the pharmaceutical, metabolomics, glycomics, and structural molecular biology fields. The book is primarily aimed at researchers, appealing to practising chemists and biochemists, as well as those in the pharmaceutical and medical fields.

Inductively Coupled Plasma Mass Spectrometry

Inductively Coupled Plasma Mass Spectrometry Book
Author : Howard E. Taylor
Publisher : Academic Press
Release : 2001
ISBN : 9780126838657
Language : En, Es, Fr & De

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Book Description :

It also includes information on processing and interpreting results to obtain high-quality data.".

Inorganic Mass Spectrometry

Inorganic Mass Spectrometry Book
Author : Sabine Becker
Publisher : John Wiley & Sons
Release : 2008-02-28
ISBN : 9780470517208
Language : En, Es, Fr & De

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Book Description :

Providing an exhaustive review of this topic, Inorganic Mass Spectrometry: Principles and Applications provides details on all aspects of inorganic mass spectrometry, from a historical overview of the topic to the principles and functions of mass separation and ion detection systems. Offering a comprehensive treatment of inorganic mass spectrometry, topics covered include: Recent developments in instrumentation Developing analytical techniques for measurements of trace and ultratrace impurities in different materials This broad textbook in inorganic mass spectrometry, presents the most important mass spectrometric techniques used in all fields of analytical chemistry. By covering recent developments and advances in all fields of inorganic mass spectrometry, this text provides researchers and students with information to answer any questions on this topic as well as providing the basic fundamentals for understanding this potentially complex, but increasingly relevant subject.

Mass Spectrometry

Mass Spectrometry Book
Author : Agnieszka Kraj,Dominic M. Desiderio,Nico M. Nibbering
Publisher : John Wiley & Sons
Release : 2008-12-01
ISBN : 047039580X
Language : En, Es, Fr & De

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Book Description :

With contributions from noted experts from Europe and North America, Mass Spectrometry Instrumentation, Interpretation, and Applications serves as a forum to introduce students to the whole world of mass spectrometry and to the many different perspectives that each scientific field brings to its use. The book emphasizes the use of this important analytical technique in many different fields, including applications for organic and inorganic chemistry, forensic science, biotechnology, and many other areas. After describing the history of mass spectrometry, the book moves on to discuss instrumentation, theory, and basic applications.

Mass Spectrometry of Natural Substances in Food

Mass Spectrometry of Natural Substances in Food Book
Author : Fred Mellon,Ron Self,James R. Startin,Royal Society of Chemistry (Great Britain)
Publisher : Royal Society of Chemistry
Release : 2000
ISBN : 9780854045716
Language : En, Es, Fr & De

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Book Description :

Introduces the principles, practice, and application of mass spectrometric techniques in the study of natural substances in foods. Early chapters address the principles and practice of mass spectrometry, followed by applications in flavor analysis and the determination of non-nutrient, biologically-active, natural substances in foods. Also covered is the analysis and metabolic study of amino acids, peptides, proteins, lipids, sugars, carbohydrates, and vitamins, with separate chapters on mineral and micronutrient metabolism and techniques of pyrolysis mass spectrometry. Annotation copyrighted by Book News, Inc., Portland, OR

Advances in Mass Spectrometry

Advances in Mass Spectrometry Book
Author : J. D. Waldron
Publisher : Elsevier
Release : 2017-01-31
ISBN : 1483184412
Language : En, Es, Fr & De

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Book Description :

Advances in Mass Spectrometry documents the proceedings of a Joint Conference on Mass Spectrometry held at the University of London, Great Britain on September 24-26, 1958. This compilation reviews the instruments, techniques, applications, and major developments in mass spectrometry over the past years. The topics discussed include the performance and image error correction of the new stigmatic focusing mass spectrograph; correction of second order aberrations in inhomogeneous magnetic sector fields; and high sensitivity solid source mass spectrometry. The isotope dilution analysis; digitization of mass spectra; ionization potentials of alkyl and halogenated alkyl free radicals; and negative ion formation and electric breakdown in some halogenated gases are also elaborated. This book likewise covers the mass spectrometer as a geological instrument and absorption and desorption of gases in the ionized state on metal and glass surfaces. This publication is a useful reference to students and researchers conducting work on mass spectrometry.

Mass Spectrometry of Biological Materials Second Edition

Mass Spectrometry of Biological Materials  Second Edition Book
Author : Barbara S. Larsen,Charles N. McEwen
Publisher : CRC Press
Release : 1998-03-02
ISBN : 9780824701574
Language : En, Es, Fr & De

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Book Description :

Second Edition provides up-to-the-minute discussions on the application of mass spectrometry to the biological sciences. Shows how and why experiments are performed and furnishes details to facilitate duplication of results.

Medical Applications of Mass Spectrometry

Medical Applications of Mass Spectrometry Book
Author : Karoly Vekey,Andreas Telekes,Akos Vertes
Publisher : Elsevier
Release : 2011-08-11
ISBN : 0080554652
Language : En, Es, Fr & De

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Book Description :

Mass spectrometry is fast becoming an indispensable field for medical professionals. The mass spectrometric analysis of metabolites and proteins promises to revolutionize medical research and clinical diagnostics. As this technology rapidly enters the medical field, practicing professionals and students need to prepare to take full advantage of its capabilities. Medical Applications of Mass Spectrometry addresses the key issues in the medical applications of mass spectrometry at the level appropriate for the intended readership. It will go a long way to help the utilization of mass spectrometry in medicine. The book comprises five parts. A general overview is followed by a description of the basic sampling and separation methods in analytical chemistry. In the second part a solid foundation in mass spectrometry and modern techniques of data analysis is presented. The third part explains how mass spectrometry is used in exploring various classes of biomolecules, including proteins and lipids. In the fourth section mass spectrometry is introduced as a diagnostic tool in clinical treatment, infectious pathogen research, neonatal diagnostics, cancer, brain and allergy research, as well as in various fields of medicine: cardiology, pulmonology, neurology, psychiatric diseases, hemato-oncology, urologic diseases, gastrointestinal diseases, gynecology and pediatrics. The fifth part covers emerging applications in biomarker discovery and in mass spectrometric imaging. * Provides a broad look at how the medical field is benefiting from advances in mass spectrometry. * Guides the reader from basic principles and methods to cutting edge applications. * There is NO comparable book on the market to fill this fast growing field.

Mass Spectrometry in Drug Metabolism and Disposition

Mass Spectrometry in Drug Metabolism and Disposition Book
Author : Mike S. Lee,Mingshe Zhu
Publisher : John Wiley & Sons
Release : 2011-03-16
ISBN : 9780470934692
Language : En, Es, Fr & De

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Book Description :

This book examines the background, industrial context, process, analytical methodology, and technology of metabolite identification. It emphasizes the applications of metabolite identification in drug research. While primarily a textbook, the book also functions as a comprehensive reference to those in the industry. The authors have worked closely together and combine complementary backgrounds to bring technical and cultural awareness to this very important endeavor while serving to address needs within academia and industry It also contains a variety of problem sets following specific sections in the text.

Mass Spectrometry

Mass Spectrometry Book
Author : James M. Thompson
Publisher : CRC Press
Release : 2017-12-22
ISBN : 135120713X
Language : En, Es, Fr & De

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Book Description :

It is estimated that there are about 10 million organic chemicals known, and about 100,000 new organic compounds are produced each year. Some of these new chemicals are made in the laboratory and some are isolated from natural products. The structural determination of these compounds is the job of the chemist. There are several instrumental techniques used to determine the structures of organic compounds. These include NMR, UV/visible, infrared spectroscopy, mass spectrometry, and X-ray crystallography. Of all the instrumental techniques listed, infrared spectroscopy and mass spectrometry are the two most popular techniques, mainly because they tend to be less expensive and give us the most structural information. This book is an introductory text designed to acquaint undergraduate and graduate students with the basic theory and interpretative techniques of mass spectrometry. Much of the material in this text has been used over a period of several years for teaching courses in materials characterization and chemical analysis. It presents the mass spectra of the major classes of organic compounds and correlates the fragmentation pattern of each spectrum with the structural features of the compound it represents. This has been done for hydrocarbons, organic acids, ketones, aldehydes, esters, anhydrides, phenols, amines, and amides. The text discusses the origin of the fragments, techniques, innovations, and applications in mass spectrometry. It is interspersed with many illustrations, examples, an adequate but not overwhelming bibliography, and problems for students. It will serve as a lecture text for a one-semester course in mass spectrometry or can be used to teach the mass spectra portion of a broader course in material characterization and chemical analysis.

Applications in High Resolution Mass Spectrometry

Applications in High Resolution Mass Spectrometry Book
Author : Roberto Romero-González,Antonia Garrido Frenich
Publisher : Elsevier
Release : 2017-03-07
ISBN : 0128096489
Language : En, Es, Fr & De

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Book Description :

Applications of High Resolution Mass Spectrometry: Food Safety and Pesticide Residue Analysis is the first book to offer complete coverage of all aspects of high resolution mass spectrometry (HRMS) used for the analysis of pesticide residue in food. Aimed at researchers and graduate students in food safety, toxicology, and analytical chemistry, the book equips readers with foundational knowledge of HRMS, including established and state-of-the-art principles and analysis strategies. Additionally, it provides a roadmap for implementation, including discussions of the latest instrumentation and software available. Detailed coverage is given to the application of HRMS coupled to ultra high-performance liquid chromatography (UHPLC-HRMS) in the analysis of pesticide residue in fruits and vegetables and food from animal origin. The book also discusses extraction procedures and the challenges of sample preparation, gas chromatography coupled to high resolution mass spectrometry, flow injection-HRMS, ambient ionization, and identification of pesticide transformation products in food. Responding to the fast development and application of these new procedures, this book is an essential resource in the food safety field. Arms researchers with an in-depth resource devoted to the rapid advances in HRMS tools and strategies for pesticide residue analysis in food Provides a complete overview of analytical methodologies and applications of HRMS, including UHPLC-HRMS, HRMS coupled with time of flight (TOF) and/or GC-Orbitrap, and flow injection-HRMS Discusses the current international regulations and legislation related to the use of HRMS in pesticide residue analysis Features a chapter on the hardware and software available for HRMS implementation Offers separate chapters on HRMS applied to pesticide residue analysis in fruits and vegetables and in food from animal origin

Mass Spectrometry Handbook

Mass Spectrometry Handbook Book
Author : Mike S. Lee
Publisher : John Wiley & Sons
Release : 2012-05-08
ISBN : 047053673X
Language : En, Es, Fr & De

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Book Description :

Due to its enormous sensitivity and ease of use, mass spectrometry has grown into the analytical tool of choice in most industries and areas of research. This unique reference provides an extensive library of methods used in mass spectrometry, covering applications of mass spectrometry in fields as diverse as drug discovery, environmental science, forensic science, clinical analysis, polymers, oil composition, doping, cellular research, semiconductor, ceramics, metals and alloys, and homeland security. The book provides the reader with a protocol for the technique described (including sampling methods) and explains why to use a particular method and not others. Essential for MS specialists working in industrial, environmental, and clinical fields.