Skip to main content

Macrophages In The Human Body

Download Macrophages In The Human Body Full eBooks in PDF, EPUB, and kindle. Macrophages In The Human Body is one my favorite book and give us some inspiration, very enjoy to read. you could read this book anywhere anytime directly from your device.

Macrophages in the Human Body

Macrophages in the Human Body Book
Author : Niels Olson Saraiva Camara,Tárcio Teodoro Braga
Publisher : Academic Press
Release : 2022-06-20
ISBN : 0128213868
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Through recent research, there has been a significant number of findings involving the biology of macrophages. Beyond the 1st line of defense, macrophages have several specific characteristics across different tissues, organs, and systems. Macrophages comprehend a heterogeneous phagocytic population with wide range phenotypes, and tissue-specific functions, such as bone resorption, extracellular matrix production, red blood cells and bacteria removal, among others. Through innate immune receptors macrophages can modulate several pathways that culminate in the production of various types of inflammatory mediators such as chemokines, cytokines, oxygen reactive species, and lipid mediators which ultimately altered the behavior of other cells. Moreover, environment signals modify and induce metabolic reprograming that it alters phenotype and functions. Macrophages in the Human Body: A Tissue Level Approach presents a current overview of the diversity of macrophages across multiple human body systems, their phenotype, function and metabolic characteristics. It covers translational aspects where there is research support to indicate the therapeutic potential. Covers translational aspects where there is research support to indicate potential therapeutic potential Aims at presenting a current overview of the diversity of macrophages across multiple human body systems, their phenotype, function and metabolic characteristics Introduces Macrophages generally and dive into the organ/tissue/specific representations covering their phenotype, function, and metabolic characteristics Brings updated aspects of macrophages biology

Janeway s Immunobiology

Janeway s Immunobiology Book
Author : Kenneth M. Murphy
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Download Janeway s Immunobiology book written by Kenneth M. Murphy, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Molecular Biology of the Cell

Molecular Biology of the Cell Book
Author : Bruce Alberts
Publisher : Unknown
Release : 2004
ISBN : 9780815332183
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Download Molecular Biology of the Cell book written by Bruce Alberts, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Macrophages in the Human Body

Macrophages in the Human Body Book
Author : Niels Olson Saraiva Camara,Tárcio Teodoro Braga
Publisher : Elsevier
Release : 2022-06-15
ISBN : 012821385X
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Through recent research, there has been a significant number of findings involving the biology of macrophages. Beyond the 1st line of defense, macrophages have several specific characteristics across different tissues, organs, and systems. Macrophages comprehend a heterogeneous phagocytic population with wide range phenotypes, and tissue-specific functions, such as bone resorption, extracellular matrix production, red blood cells and bacteria removal, among others. Through innate immune receptors macrophages can modulate several pathways that culminate in the production of various types of inflammatory mediators such as chemokines, cytokines, oxygen reactive species, and lipid mediators which ultimately altered the behavior of other cells. Moreover, environment signals modify and induce metabolic reprograming that it alters phenotype and functions. Macrophages in the Human Body: A Tissue Level Approach presents a current overview of the diversity of macrophages across multiple human body systems, their phenotype, function and metabolic characteristics. It covers translational aspects where there is research support to indicate the therapeutic potential. Covers translational aspects where there is research support to indicate potential therapeutic potential Aims at presenting a current overview of the diversity of macrophages across multiple human body systems, their phenotype, function and metabolic characteristics Introduces Macrophages generally and dive into the organ/tissue/specific representations covering their phenotype, function, and metabolic characteristics Brings updated aspects of macrophages biology

Macrophage Activation

Macrophage Activation Book
Author : Khalid Hussain Bhat
Publisher : BoD – Books on Demand
Release : 2020-03-25
ISBN : 1789846447
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Macrophages are the sentinels of the immune system whose role has evolved beyond providing aseptic conditions to homeostasis, immune regulation, development, and behaviour. These cells have varied ontogenetic origins which reflects in their phenotypic and functional heterogeneity. Macrophage functions are fine-tuned by exogenous and endogenous signals and once tweaked, the information is included in their genetic makeup, albeit not indefinitely. Subversion of the macrophage functions is the hallmark of many pathogenic organisms and modulation of macrophage activity is pivotal to many therapeutic strategies. Fascinating and rapid developments in this field have necessitated the maintenance of currency of knowledge. This book provides a current account of information on varied topics in macrophage biology. Literature surveys have been presented in a captivating and lucid language. The contributing authors have also provided brief accounts of their own research. Every chapter provides a future perspective of what more could be achieved in the context of the current knowledge. The book will be of interest to students and researchers in microbiology, immunobiology, translational research, pathology, and related fields.

Human Monocytes

Human Monocytes Book
Author : Marek Zembala,G. L. Asherson
Publisher : Unknown
Release : 1989
ISBN : 0987650XXX
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Monocytes represent one of the major types of white blood cells in man which prevent infection by ingesting and killing invading pathogens and by releasing factors which stimulate and regulate lymphocytes. Monocytes "purify" the blood, removing immune complexes, mediating inflammatory responses, and initiating tissue repair. Human Monocytes represents an up-to-date, definitive account of this important cell. It covers the cells biochemical, immunological, and inflammatory functionsand its role in many diseases, including asthma, atherosclerosis, rheumatoid arthritis, and AIDS.

Macrophages

Macrophages Book
Author : Donna M. Paulnock
Publisher : OUP Oxford
Release : 2000-09-14
ISBN : 0191565784
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Macrophages are an important part of the immune response and are characterized by their ability to phagocytose foreign matter. However the difficulties involved in macrophage isolation mean they are some of the body's least explored cells. Macrophage Methodology describes how to isolate moderate to high yields of viable cells from a variety of specific tissue sites under both normal and pathological conditions and then goes on to give protocols for macrophage purification. The third chapter covers techniques used to identify and measure endocytic and phagocytic capabilities using immunochemistry and fluorescent analysis. Chapter four identifies the key issues relating to the study of macrophages as antigen presenting cells and has protocols for the major assays used to measure antigen processing and presentation. Also covered are the theoretical and practical issues related to the processing and presentation of intracellular pathogens for which macrophages are the major host cell. The methods described for measuring macrophage secretory products concentrate on bioassays for molecules where no ELISA is available. The next two chapters cover measuring macrophage activity in vitro and in vivo. Finally methods are described for the analysis of gene expression in macrophages. A variety of broad techniques have been brought together in one affordable volume to make Macrophage Methodology an essential buy for anyone studying macrophages.

Handbook on Immunosenescence

Handbook on Immunosenescence Book
Author : Tamas Fulop,Claudio Franceschi,Katsuiki Hirokawa,Graham Pawelec
Publisher : Springer Science & Business Media
Release : 2009-02-27
ISBN : 1402090633
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

This authoritative handbook covers all aspects of immunosenescence, with contributions from experts in the research and clinical areas. It examines methods and models for studying immunosenescence; genetics; mechanisms including receptors and signal transduction; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; and much more.

Macrophages in Liver Disease

Macrophages in Liver Disease Book
Author : Ruchi Bansal,Pranoti Mandrekar,Sujit K. Mohanty,Ralf Weiskirchen
Publisher : Frontiers Media SA
Release : 2020-10-08
ISBN : 2889660389
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Biomaterials in Regenerative Medicine and the Immune System

Biomaterials in Regenerative Medicine and the Immune System Book
Author : Laura Santambrogio
Publisher : Springer
Release : 2015-09-04
ISBN : 3319180452
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

The generation of tridimensional tissues, assembled from scaffolding materials populated with biologically functional cells, is the great challenge and hope of tissue bioengineering and regenerative medicine. The generation of biomaterials capable of harnessing the immune system has been particularly successful. This book provides a comprehensive view of how immune cells can be manipulated to suppresses inflammation, deliver vaccines, fight cancer cells, promote tissue regeneration or inhibit blood clotting and bacterial infections by functionally engineered biomaterials. However, long-lived polymers, such as those employed in orthopedic surgery or vascular stents, can often induce an immune reaction to their basic components. As a result, this book is also an important step towards coming to understand how to manipulate biomaterials to optimize their beneficial effects and downplay detrimental immune responses.

Macrophages Biology and Role in the Pathology of Diseases

Macrophages  Biology and Role in the Pathology of Diseases Book
Author : Subhra K. Biswas,Alberto Mantovani
Publisher : Springer
Release : 2014-11-12
ISBN : 1493913115
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Macrophages are a key component of the innate immune system and play an integral role in host defense and homeostasis. On one hand, these cells contribute to host defence by triggering inflammation, displaying microbicidal/tumoricidal properties, regulating the activation of adaptive immunity and promoting resolution of inflammation. On the other hand, they contribute to essential trophic functions such as neural patterning, bone morphogenesis and ductal branching in mammary glands. Thus, macrophages are extremely versatile cells that can respond efficiently to tissue micro environmental cues by polarizing to distinct phenotypes, depending on the functions they need to perform. Indeed, functional diversity and plasticity are hallmarks of these cells. Macrophages may also play a detrimental role. An overwhelming body of literature has indicated their crucial role in pathogenesis. The list includes sepsis, cancer, metabolic syndrome, immunodeficiency, auto-immune disease-virtually impacting every major pathology that we know. These observations have suggested macrophages and their related molecules as potential targets in therapeutic applications. Available evidence proclaims macrophages as a key player in homeostasis, host defense and disease. Crucial developments in the past few years call for a re-evaluation and update of our understanding of macrophages. The present book is an endeavour that attempts provide state-of-the art knowledge of these cells in health and disease.

The Immune Response to Implanted Materials and Devices

The Immune Response to Implanted Materials and Devices Book
Author : Bruna Corradetti
Publisher : Springer
Release : 2016-11-30
ISBN : 3319454331
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

This book provides a comprehensive overview of the cascade of events activated in the body following the implant of biomaterials and devices. It is one of the first books to shed light on the role of the host immune response on therapeutic efficacy, and reviews the state-of-the-art for both basic science and medical applications. The text examines advantages and disadvantages of the use of synthetic versus natural biomaterials. Particular emphasis is placed on the role of biomimicry in the development of smart strategies able to modulate infiltrating immune cells, thus reducing side effects (such as acute and chronic inflammation, fibrosis and/or implant rejection) and improving the therapeutic outcome (healing, tissue restoration). Current cutting-edge approaches in tissue engineering, regenerative medicine, and nanomedicine offer the latest insights into the role immunomodulation in improving tolerance during tissue transplant in the treatment of orthopaedic, pancreatic, and hepatic diseases. "Immune Response to Implanted Materials and Devices" is intended for an audience of graduate students and professional researchers in both academia and industry interested in the development of smart strategies, which are able to exploit the self-healing properties of the body and achieve functional tissue restoration.

Macrophages and Dendritic Cells

Macrophages and Dendritic Cells Book
Author : David Johnson
Publisher : Unknown
Release : 2022-09-20
ISBN : 9781639893379
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

The white blood cells which are involved in the detection, phagocytosis and destruction of harmful organisms such as bacteria are termed as macrophages. Anything within the body which does not have the proteins on its surface which are found in healthy human cells are digested by these cells. Some of the harmful organisms and cells digested by macrophages are cancer cells, microbes and foreign substances. The cells which are responsible for processing antigen material and presenting it to the T cells of the immune system on the surface of the cell are termed as dendritic cells. Macrophages, dendritic cells and monocytes together make up the mononuclear phagocyte system. This book contains some path-breaking studies on macrophages and dendritic cells. It consists of contributions made by international experts. This book will serve as a valuable source of reference for graduate and post graduate students.

Cooperation of Liver Cells in Health and Disease

Cooperation of Liver Cells in Health and Disease Book
Author : Z. Kmiec
Publisher : Springer Science & Business Media
Release : 2013-06-29
ISBN : 3642565530
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

It is only during the last decade that the functions of sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, pit cells and other intrahepatic lymphocytes have been better understood. The development of methods for isolation and co-culturing various types of liver cells has established that they communicate and cooperate via secretion of various intercellular mediators. This monograph summarizes multiple data that suggest the important role of cellular cross-talk for the functions of both normal and diseased liver. Special features of the book include concise presentation of the majority of detailed data in 19 tables. Original schemes allow for the clear illustration of complicated intercellular relationships. This is the first ever presentation of the newly emerging field of liver biology, which is important for hepatic function in health and disease and opens new avenues for therapeutic interventions.

One No One One Hundred Thousand The Multifaceted Role of Macrophages in Health and Disease Part B

One  No One  One Hundred Thousand   The Multifaceted Role of Macrophages in Health and Disease   Part B Book
Author : Anonim
Publisher : Academic Press
Release : 2022-05-28
ISBN : 032390744X
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

One, No One, One Hundred Thousand - The Multifaceted Role of Macrophages in Health and Disease - Part B, Volume 369 provides in-depth reviews on the last progresses on the role of macrophages in health and diseases, with a special focus on the role of macrophages during development. New chapters cover The role of salivary gland macrophages in infection, disease and repair, Reprogramming or replacing brain macrophages to treat neurodegenerative disease, Targeting macrophages for cancer immunotherapy, Heart Macrophages at steady-state and disease: simple bystanders or active players?, Macrophages in the liver, and Developmental programming of macrophages. Provides accurate reviews from selected experts on the topic of macrophages in different tissues such as gut, kidney and heart Presents useful graphic material for ease of reading and learning for users Covers the latest insights and future perspectives on macrophage heterogeneity in different diseases

The Resolution of Inflammation

The Resolution of Inflammation Book
Author : Adriano Rossi,Deborah A. Sawatzky
Publisher : Springer Science & Business Media
Release : 2008-03-17
ISBN : 376437506X
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

This book provides readers with an up-to-date and comprehensive view on the resolution of inflammation and on new developments in this area, including pro-resolution mediators, apoptosis, macrophage clearance of apoptotic cells, possible novel drug developments.

The Biology of Subcellular Nitric Oxide

The Biology of Subcellular Nitric Oxide Book
Author : Tamás Rőszer
Publisher : Springer Science & Business Media
Release : 2012-01-14
ISBN : 9400728190
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

This book fills in a gap in the NO literature. Recent progress in the field of NO-biology shows that NO is generated within distinct cell compartments, including specific plasma membrane regions, mitochondria, chloroplasts, peroxisomes, the Golgi-complex and intracellular membrane systems. NO synthesis plays specific roles in these compartments and, in turn, cell organelles also control intracellular NO levels. This monograph focuses on the roles played by the subcellular NO-signaling microdomains in the prokaryote-, fungus-, plant- and animal cells and shows how NO behaves as an intracellular signal in distinct cellular environments. This monograph also provides a summary of our knowledge on how NO synthesis came through evolution to be associated with organelles and subcellular compartments. Promotes the novel ideas that some functions of NO and its associations with subcellular units have been conserved during the evolution of the cell. A special chapter is dedicated to the biomedical relevance of subcellular NO synthesis, and this chapter also discusses the evidence that altered compartmentalization of NO-producing enzymes causes disease.

Environmental Hygiene III

Environmental Hygiene III Book
Author : Norbert H. Seemayer,Wolfgang Hadnagy
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 3642771122
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

ENVIRONMENTAL HYGIENE III deals with the detection and evaluation of environmental pollutants as well as with their relevance to human health. Environmental components are important determinants of the health status of groups at risk and of the general population. The main objective is the early detection and identification of hazardous substances by physical, chemical and biological methods, risk assessment andprotection of human health. Faced with these problems the volume gives an overview on the mulifaceted aspects of environmental hygiene and medicine. Contributions include basic and innovative approaches in the fields of - Experimental cell biology - Cytotoxicity testing - Mutagenicity and carcinogenicity studies - Inhalation toxicity - Human exposure monitoring - Epidemiology - Important harzardous agents - Environmental control, prevention and legislation.

The Role of Matrix Metalloproteinase in Human Body Pathologies

The Role of Matrix Metalloproteinase in Human Body Pathologies Book
Author : Francesco Travascio
Publisher : BoD – Books on Demand
Release : 2017-12-20
ISBN : 9535137174
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Matrix metalloproteinases (MMPs) are a family of proteolytic zinc-containing enzymes involved in physiological as well as in pathological processes in the human organism. MMPs play a key role in the remodeling of the extracellular matrix. Such a process may occur because of tissue homeostasis, morphogenesis, and tissue repair. However, remodeling could also be a part of many pathological states such as arthritis, cardiovascular diseases, neurodegenerative diseases, or impaired development in congenital anomalies. This book overviews the role of MMPs in different pathologies affecting the human body.

Fundamental Immunology

Fundamental Immunology Book
Author : William E. Paul
Publisher : Lippincott Williams & Wilkins
Release : 1989
ISBN : 0987650XXX
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

The defining reference work in immunology today is now available in an "entirely new text"! This edition places greater emphasis on molecular mechanisms underlying cellular function and physiology, and includes outstanding new chapters on neuroimmunology and immunotherapy...completely updated coverage of immune suppression and regulatory T cells...and new and expanded chapters on lymphocytes, the immunology of aging, autoimmunity, and more. "A free CD-ROM" provides one-click access to all of the content and illustrations from the text— plus Internet links to PubMed and 50 other sites. "Nothing else competes with it."— JAMA, review of the previous edition