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Liver Regeneration

Liver Regeneration Book
Author : Dieter Häussinger
Publisher : Walter de Gruyter
Release : 2011
ISBN : 3110250780
Language : En, Es, Fr & De

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Book Description :

Understanding the mechanisms involved in liver regeneration is of crucial importance for clinical medicine, not only regarding carcinogenesis and diabetes treatment, but also for the use of stem cells for cell therapy and liver surgery. This graduate-level text provides an overview of the current state of knowledge of the molecular mechanisms of liver regeneration. Hepatic stem cells are introduced and the important players involved in regeneration such as oval cells, bone marrow and stellate cells are reviewed. The cell signaling pathways that initiate liver regeneration and regulate the switch between proliferation and apoptosis are presented and the role of liver stem cells in tumorigenesis is discussed. The book also treats the epigenetic regulation of liver stem cells and the roles of inflammation and angiogenesis in liver regeneration. This compact overview of the fascinating regenerative capacity of the liver will be of interest to graduate students and post-docs in molecular biology, biochemistry and medicine.

Stem Cell and Liver Regeneration

Stem Cell and Liver Regeneration Book
Author : K. Okita
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 4431539719
Language : En, Es, Fr & De

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Book Description :

Cellular therapy with liver stem cells and their progeny, including bone marrow cells, is a promising new approach that will contribute significantly to the treatment of liver diseases. The existence of the liver stem cell had long been debated, but it is now generally accepted that the liver contains cells with stem-like properties and that these cells can be activated to proliferate and differentiate into mature hepatocytes under certain conditions. There is also a substantial body of evidence to suggest that oval cells are involved in liver regeneration as they differentiate into hepatocytes and biliary cells. This book is a collection of work on stem cell and liver regeneration, initially delivered at the 14th Yamaguchi (Japan) Symposium on Liver Disease. Its nine chapters present the most recent data about basic and clinical research in hepatology in Japan and other countries, providing a valuable resource for researchers and practitioners alike.

Liver Regeneration

Liver Regeneration Book
Author : Udayan M. Apte
Publisher : Academic Press
Release : 2015-08-13
ISBN : 0128004312
Language : En, Es, Fr & De

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Book Description :

Liver Regeneration: Basic Mechanisms, Relevant Models and Clinical Applications presents cutting-edge information on liver regeneration research through an integrated, systems-wide perspective. The book addresses discoveries on hepatic progenitor cells, liver regeneration after chemical damage, and liver regeneration as a prime therapy for liver failure and disease. By addressing the urgent need for translating basic research findings into clinically relevant modalities and potential therapeutic applications, the book provides the data needed to improve liver patient management. Hundreds of full-color, graphic photographs and illustrations underline key elements and show researchers and students important aspects of liver transplantation, immunofluorescence, and other techniques used in liver regeneration. Summarizes current liver regeneration studies and discussions on expected discoveries Provides an overview of standard scientific and cutting-edge technologies to study liver regeneration Presents details on the molecular mechanisms that affect liver regeneration Highly illustrated, with hundreds of full-color, graphic photographs and illustrations to enhance the learning process

Liver Regeneration and Carcinogenesis

Liver Regeneration and Carcinogenesis Book
Author : Gerard Meurant
Publisher : Elsevier
Release : 1995-09-27
ISBN : 9780080535548
Language : En, Es, Fr & De

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Book Description :

Because of its marked capacity to regenerate and the ability of chemical carcinogens and viruses to ready transform hepatocytes, the liver has been used extensively as a model for investigating the molecular mechanisms of cellular proliferation and carcinogenesis. Recently, striking advances have occured in the understanding of hepatocyte growth regulation and the manner in which chemical agents and viruses alter these normal growth regulatory pathways in liver carcinogenesis. This explosion of information has occured in a multitude of researh disciplines. This book brings together current findings in a coherent manner, from a molecular point of view. Three sections cover in detail the areas of liver regeneration, liver carcinogenesis, and liver tumor therapy. The contributors are pioneers and leaders in this field. * Logical organization of material in three detailed and comprehensive sections: liver regeneration, liver carcinogenesis, and liver tumor treatment * Contributors are pioneers and leaders in the field * There are currently no books on this subject on the market * Research focus is at the molecular level

Liver regeneration

Liver regeneration Book
Author : Nelson Fausto
Publisher : Ardent Media
Release : 1973
ISBN : 9780842270809
Language : En, Es, Fr & De

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Book Description :

Download Liver regeneration book written by Nelson Fausto, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Regeneration of Liver and Kidney

Regeneration of Liver and Kidney Book
Author : Nancy L. R. Bucher,Ronald A. Malt
Publisher : Unknown
Release : 1971
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Regeneration of Liver and Kidney book written by Nancy L. R. Bucher,Ronald A. Malt, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Liver Regeneration

Liver Regeneration Book
Author : D. Bernuau
Publisher : John Libbey Eurotext
Release : 1992
ISBN : 9780861963478
Language : En, Es, Fr & De

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Book Description :

Presents an approach to the hepatic physiology and multiple developments about cellular biology such as cell cycle regulation, growth factors and oncogenes.

Liver Regeneration

Liver Regeneration Book
Author : Pedro Baptista
Publisher : BoD – Books on Demand
Release : 2012-05-16
ISBN : 9535106228
Language : En, Es, Fr & De

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Book Description :

Doctors and scientists have been aware of the "phenomenom" of liver regeneration since the time of the ancient Greeks, illustrated by the mythic tale of Prometheus' punishment. Nevertheless, true insight into its intricate mechanisms have only become available in the 20th century. Since then, the pathways and mechanisms involved in restoring the liver to its normal function after injury have been resolutely described and characterized, from the hepatic stem/progenitor cell activation and expansion to the more systemic mechanisms involving other tissues and organs like bone-marrow progenitor cell mobilization. This book describes some of the complex mechanisms involved in liver regeneration and provides examples of the most up-to-date strategies used to induce liver regeneration, both in the clinic and in the laboratory. The information presented will hopefully benefit not only professionals in the liver field, but also people in other areas of science (pharmacology, toxicology, etc) that wish to expand their knowledge of the fundamental biology that orchestrates liver injury and regeneration.

Liver Regeneration and Partial Liver Transplantation

Liver Regeneration and Partial Liver Transplantation Book
Author : Aksel Foss
Publisher : Unknown
Release : 1992
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Liver Regeneration and Partial Liver Transplantation book written by Aksel Foss, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Liver Regeneration

Liver Regeneration Book
Author : Anonim
Publisher : Unknown
Release : 1973
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Liver Regeneration book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Stem Cell and Liver Regeneration

Stem Cell and Liver Regeneration Book
Author : K Okita
Publisher : Unknown
Release : 2003-12-01
ISBN : 9784431539728
Language : En, Es, Fr & De

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Book Description :

Download Stem Cell and Liver Regeneration book written by K Okita, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The effect of feeding liver on liver regeneration in rats

The effect of feeding liver on liver regeneration in rats Book
Author : Robert Webster Denton
Publisher : Unknown
Release : 1946
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The effect of feeding liver on liver regeneration in rats book written by Robert Webster Denton, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Liver Regeneration in Man

Liver Regeneration in Man Book
Author : Carroll Moton Leevy
Publisher : Charles C. Thomas Publisher
Release : 1973
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Liver Regeneration in Man book written by Carroll Moton Leevy, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Role of Monocyte Chemoattractant Protein 1 During Liver Regeneration

Role of Monocyte Chemoattractant Protein 1 During Liver Regeneration Book
Author : Stephanie Wyler
Publisher : Unknown
Release : 2015
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

"Liver regeneration is a complex process that requires the coordinated expression of cytokines and growth factors. One well-studied model of liver regeneration is partial hepatectomy (PH), in which removal of 70% of the liver initiates compensatory hepatocyte proliferation. PH-induced liver regeneration requires the activation of resident macrophages (Kupffer cells), which produce cytokines that drive hepatocyte proliferation. Monocyte chemoattractant protein-1 (MCP-1) is a chemokine that is known to activate macrophages and recruit monocytes during tissue injury. The goal of this study was to determine how MCP-1 contributes to macrophage activation during liver regeneration. Results indicate that hepatic and plasma MCP-1 levels increased within 12 hr after PH and correlated with hepatic recruitment of cells expressing the MCP-1 receptor, CCR2. Nevertheless, hepatocyte proliferation was comparable in MCP-1 knockout and wild-type mice, as was the expression of Kupffer cell-derived cytokines. Furthermore, hepatic recruitment of CCR2+ cells was similar in MCP-1 knockout and wild-type mice, which suggests that other chemokines may efficiently recruit CCR2+ cells in the absence of MCP-1. CCR2 appears to be required for optimal regeneration, as CCR2 knockout mice had levels of hepatocyte proliferation that were 50% lower than wild-type mice 36 hr after PH. We conclude that MCP-1 is not required for macrophage activation during PH-induced liver regeneration. Future studies should instead focus on mechanisms by which CCR2 signaling events and the hepatic recruitment of CCR2-expressing cells facilitates hepatocyte proliferation during liver regeneration."--Boise State University ScholarWorks.

Essential Topics in Liver Regeneration

Essential Topics in Liver Regeneration Book
Author : Amelia Foster
Publisher : Unknown
Release : 2015-01-13
ISBN : 9781632421821
Language : En, Es, Fr & De

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Book Description :

This book intends to provide detailed information regarding essential topics in liver regeneration. Doctors and scientists have been familiar with the phenomenon of liver regeneration ever since the tale of Prometheus' punishment in ancient Greek mythology. However, true insight into its complex mechanisms has only become available in the 20th century. Consequently, the pathways and mechanisms involved in regeneration of the liver to its normal function after injury have been well described and characterized, from the hepatic stem/progenitor cell activation and expansion to the more systemic mechanisms involving other tissues and organs like bone-marrow progenitor cell mobilization. This book discusses some of the intricate mechanisms involved in liver regeneration and provides instances of latest strategies adopted to induce liver regeneration, both in clinic and laboratory. The information provided will be beneficial not only to professionals engaged in this field, but also to practitioners in other areas of science such as pharmacology, toxicology, etc. who are interested in updating their knowledge regarding the underlying biology that revolves around liver injury and regeneration.

Effect of Bone Marrow derived Mesenchymal Stromal Cells on Liver Regeneration After Partial Hepatectomy in Pathological Liver Conditions

Effect of Bone Marrow derived Mesenchymal Stromal Cells on Liver Regeneration After Partial Hepatectomy in Pathological Liver Conditions Book
Author : Nele Boeykens
Publisher : Unknown
Release : 2013
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Effect of Bone Marrow derived Mesenchymal Stromal Cells on Liver Regeneration After Partial Hepatectomy in Pathological Liver Conditions book written by Nele Boeykens, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Surgery of the Liver and Biliary Tract

Surgery of the Liver and Biliary Tract Book
Author : L. H. Blumgart
Publisher : Unknown
Release : 1988
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Surgery of the Liver and Biliary Tract book written by L. H. Blumgart, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Cell Based Liver Regeneration

Cell Based Liver Regeneration Book
Author : Hala Gabr,Wael Abo El-Kheir
Publisher : Academic Press
Release : 2021-09-15
ISBN : 9780128223406
Language : En, Es, Fr & De

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Book Description :

Stem cell therapy is a fast-growing field of medicine with remarkable prospects in a broad spectrum of diseases. Cell-Based Liver Regeneration: Current Aspects and Future Approaches addresses the full spectrum of regenerative medicine in liver diseases. Coverage will include the basic science, current research and a comprehensive review of clinical trials conducted in the field. The book will discuss the various types of stem cells for liver regeneration, presenting the advantages and disadvantages of each type. A review of all aspects of implanting stem cell therapy for the liver, such as: choosing the cell type, the source, laboratory manipulation, dose, route and follow-up. The book concludes with a full discussion of the current clinical trials involving cellular therapy in liver regeneration. Cell-Based Liver Regeneration: Current Aspects and Future Approaches is written for stem cell biologists, liver biologists, hepatologists and graduate students by authors with extensive knowledge in basic, pre-clinical and clinical stem cell research. Introduces basic concepts of liver regeneration Discusses the various types of stem cells used in liver regeneration Explores published and ongoing clinical trials involving cellular therapy in liver regeneration

Protein Profile in Liver Regeneration After Partial Heptectomy

Protein Profile in Liver Regeneration After Partial Heptectomy Book
Author : Farouk Aly Hanan
Publisher : LAP Lambert Academic Publishing
Release : 2015-07-06
ISBN : 9783659754982
Language : En, Es, Fr & De

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Book Description :

Most of serum proteins are synthesized by the liver, which decreased in its concentration in response to partial hepatectomy and this may be due to reduction in liver mass, the production of liver protein is mainly directed to the regenerating process than the production of the exported serum proteins. Serum proteins have a dynamic existence with degradation and synthesis continuously replacing the protein circulating at any time, the rate of synthesis equals the rate of degradation, so the concentration Of protein in serum remain s constant, so that the tendency for concentration of serum, proteins to remain constant implies, the existence of a mechanism determining the rate of production, the rate of degradation or both . In case of proteins whose serum level fall (ceruloplasmin, -l-antitrypsin, prealbumin, B-lipoprotein, -1-macroglobulin, -1-acidglycoprotein, cholinesterase and haemopexin) particularly those with small molecular size as albumin, transferrin are accompanied by an increase in degradation of albumin or increase in catabolism must exceed increase in the synthesis . The changes in rates of degradation of individual proteins do not parallel with the changes in rat"

IL 17A Regulates Liver Injury and Liver Regeneration Through B1a Cells

IL 17A Regulates Liver Injury and Liver Regeneration Through B1a Cells Book
Author : 張維逸
Publisher : Unknown
Release : 2020
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download IL 17A Regulates Liver Injury and Liver Regeneration Through B1a Cells book written by 張維逸, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.