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Liver Pathophysiology

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Liver Pathophysiology

Liver Pathophysiology Book
Author : Pablo Muriel
Publisher : Academic Press
Release : 2017-03-02
ISBN : 0128043210
Language : En, Es, Fr & De

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Book Description :

Liver Pathophysiology: Therapies and Antioxidants is a complete volume on morphology, physiology, biochemistry, molecular biology and treatment of liver diseases. It uses an integral approach towards the role of free radicals in the pathogenesis of hepatic injury, and how their deleterious effects may be abrogated by the use of antioxidants. Written by the most prominent authors in the field, this book will be of use to basic and clinical scientists and clinicians working in the biological sciences, especially those dedicated to the study and treatment of liver pathologies. Presents the most recent advances in hepatology, with a special focus on the role of oxidative stress in liver injury. Provides in vivo and in vitro models to study human liver pathology. Explains the beneficial effects of antioxidants on liver diseases. Contains the most recent and modern treatments of hepatic pathologies, including, but not limited to, stem cells repopulation, gene therapy and liver transplantation.

Chronic Liver Failure

Chronic Liver Failure Book
Author : Pere Ginès,Patrick S Kamath,Vicente Arroyo
Publisher : Springer Science & Business Media
Release : 2010-11-03
ISBN : 1607618664
Language : En, Es, Fr & De

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Book Description :

Chronic liver failure is a frequent condition in clinical practice that encompasses all manifestations of patients with end-stage liver diseases. Chronic liver failure is a multiorgan syndrome that affects the liver, kidneys, brain, heart, lungs, adrenal glands, and vascular, coagulation, and immune systems. Chronic Liver Failure: Mechanisms and Management covers for the first time all aspects of chronic liver failure in a single book, from pathogenesis to current management. Each chapter is written by a worldwide known expert in their area and all provide the latest state-of-the-art knowledge. This volume is specifically designed to provide answers to clinical questions to all doctors dealing with patients with liver diseases, not only clinical gastroenterologists and hepatologists, but also to internists, nephrologists, intensive care physicians, and transplant surgeons.

Pathophysiology of Disease An Introduction to Clinical Medicine 7 E ENHANCED EBOOK

Pathophysiology of Disease  An Introduction to Clinical Medicine 7 E  ENHANCED EBOOK  Book
Author : Gary D. Hammer,Stephen J. McPhee
Publisher : McGraw Hill Professional
Release : 2014-03-22
ISBN : 0071806016
Language : En, Es, Fr & De

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Book Description :

A full-color, case-based review of the essentials of pathophysiology--covering all major organs and systems The goal of this trusted text is to introduce you to clinical medicine by reviewing the pathophysiologic basis of 120 diseases (and associated signs and symptoms) commonly encountered in medical practice. The authors, all experts in their respective fields, have provided a concise review of relevant normal structure and function of each body system, followed by a description of the pathophysiologic mechanisms that underlie several common diseases related to that system. Each chapter of Pathophysiology of Disease concludes with a collection of case studies and questions designed to test your understanding of the pathophysiology of each clinical entity discussed. These case studies allow you to apply your knowledge to specific clinical situations. Detailed answers to each case study question are provided at the end of the book. This unique interweaving of physiological and pathological concepts will put you on the path toward thinking about signs and symptoms in terms of their pathophysiologic basis, giving you an understanding of the "why" behind illness and treatment. Features 120 case studies (9 new) provide an opportunity for you to test your understanding of the pathophysiology of each clinical entity discussed Checkpoint questions provide review and appear in every chapter Updates and revisions throughout this new edition reflect the latest research and developments Numerous tables and diagrams encapsulate important information Updated references for each chapter topic Pathophysiology of Disease is a true must-have resource for medical students preparing for the USMLE Step 1 exam, as well as students engaged in their clerkship studies. House officers, nurses, nurse practitioners, physicians’ assistants, and allied health practitioners will find its concise presentation and broad scope a great help in facilitating their understanding of common disease entities.

Drug Induced Liver Injury

Drug Induced Liver Injury Book
Author : Anonim
Publisher : Academic Press
Release : 2019-07-13
ISBN : 0128173173
Language : En, Es, Fr & De

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Book Description :

Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series

Liver Disease in Children

Liver Disease in Children Book
Author : Frederick J. Suchy,Ronald J. Sokol,William F. Balistreri
Publisher : Cambridge University Press
Release : 2014-02-20
ISBN : 1107729092
Language : En, Es, Fr & De

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Book Description :

The fourth edition of this authoritative text covers every aspect of liver disease affecting infants, children and adolescents. As in the previous editions, it offers an integrative approach to the science and clinical practice of pediatric hepatology and charts the substantial progress in understanding and treating these diseases. All of the chapters are written by international experts and address the unique pathophysiology, manifestations and management of these disorders. This edition of the landmark text features extended coverage of viral hepatitis, metabolic liver disease, fatty liver disease and liver transplantation, including a new chapter on post-transplant care and outcomes. All of the chapters have been updated to reflect changing epidemiology and recent advances in molecular medicine and genomics. With the continued evolution of pediatric hepatology as a discipline, this text remains an essential reference for all physicians involved in the care of children with liver disease.

Sleisenger and Fordtran s Gastrointestinal and Liver Disease E Book

Sleisenger and Fordtran s Gastrointestinal and Liver Disease E Book Book
Author : Mark Feldman,Lawrence S. Friedman,Lawrence J. Brandt
Publisher : Elsevier Health Sciences
Release : 2015-01-01
ISBN : 1455749893
Language : En, Es, Fr & De

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Book Description :

Consult this title on your favorite e-reader. Get the essential gastroenterology information you need from one authoritative source with an outstanding global reputation for excellence. Zero in on the key information you need to know with a consistent, full-color chapter design. Stay up to date with emerging and challenging topics: enteric microbiota and probiotics; fecal microbiota transplantation; Clostridium difficile colitis; and factitious gastrointestinal diseases. Incorporate the latest findings and improvements in care for liver disease patients—from diagnosis and treatment through post-treatment strategies and management of complications. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.

The Liver

The Liver Book
Author : Irwin M. Arias,Harvey J. Alter,James L. Boyer,David E. Cohen,David A. Shafritz,Snorri S. Thorgeirsson,Allan W. Wolkoff
Publisher : John Wiley & Sons
Release : 2020-01-22
ISBN : 1119436834
Language : En, Es, Fr & De

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Book Description :

Bridging the gap between basic scientific advances and the understanding of liver disease — the extensively revised new edition of the premier text in the field. The latest edition of The Liver: Biology and Pathobiology remains a definitive volume in the field of hepatology, relating advances in biomedical sciences and engineering to understanding of liver structure, function, and disease pathology and treatment. Contributions from leading researchers examine the cell biology of the liver, the pathobiology of liver disease, the liver’s growth, regeneration, metabolic functions, and more. Now in its sixth edition, this classic text has been exhaustively revised to reflect new discoveries in biology and their influence on diagnosing, managing, and preventing liver disease. Seventy new chapters — including substantial original sections on liver cancer and groundbreaking advances that will have significant impact on hepatology — provide comprehensive, fully up-to-date coverage of both the current state and future direction of hepatology. Topics include liver RNA structure and function, gene editing, single-cell and single-molecule genomic analyses, the molecular biology of hepatitis, drug interactions and engineered drug design, and liver disease mechanisms and therapies. Edited by globally-recognized experts in the field, this authoritative volume: Relates molecular physiology to understanding disease pathology and treatment Links the science and pathology of the liver to practical clinical applications Features 16 new “Horizons” chapters that explore new and emerging science and technology Includes plentiful full-color illustrations and figures The Liver: Biology and Pathobiology, Sixth Edition is an indispensable resource for practicing and trainee hepatologists, gastroenterologists, hepatobiliary and liver transplant surgeons, and researchers and scientists in areas including hepatology, cell and molecular biology, virology, and drug metabolism.

Oxford Textbook of Critical Care

Oxford Textbook of Critical Care Book
Author : Webb
Publisher : Oxford University Press
Release : 2020-01-10
ISBN : 0198855435
Language : En, Es, Fr & De

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Book Description :

Now in paperback, the second edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely this text takes a problem-orientated approach providing a key resource for daily clinical issues in the intensive care unit. The text is organized into short topics allowing readers to rapidly access authoritative information on specific clinical problems. Each topic refers to basic physiological principles and provides up-to-date treatment advice supported by references to the most vital literature. Where international differences exist in clinical practice, authors cover alternative views. Key messages summarise each topic in order to aid quick review and decision making. Edited and written by an international group of recognized experts from many disciplines, the second edition of the Oxford Textbook of Critical Careprovides an up-to-date reference that is relevant for intensive care units and emergency departments globally. This volume is the definitive text for all health care providers, including physicians, nurses, respiratory therapists, and other allied health professionals who take care of critically ill patients.

The Complex Interplay Between Gut Brain Gut Liver and Liver Brain Axes

The Complex Interplay Between Gut Brain  Gut Liver  and Liver Brain Axes Book
Author : Cristina Stasi
Publisher : Academic Press
Release : 2021-04-06
ISBN : 0128219289
Language : En, Es, Fr & De

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Book Description :

The Complex Interplay Between Gut–Brain, Gut–Liver, and Liver–Brain Axes provides current and wide-ranging information in the field of gastrointestinal, liver, and brain interactions that can be used in resolving important clinical issues. This book is systematically split into three distinct sections. The first section introduces the pathophysiology of the gut–brain connection, including the causative effect of the interactions between the gut and brain in gastrointestinal and psychiatric/neurological disorders, and the role of serotonin and its pathways in gastrointestinal disorders. The second section examines the pathophysiology of the gut–liver connection along with the interactions between gut microbiota and liver in chronic liver diseases, with special focus on the role of serotonin and its pathways in hepatic fibrogenesis. Finally, the third section describes the pathophysiology of the liver–brain connection, including the role of gut microbiota in hepatic encephalopathy, as well as dietary and therapeutic interventions that target the gut microbiome. Provides current and wide-ranging knowledge in the field of gastrointestinal, liver, and brain interactions. Resolves important clinical issues concerning gut, liver, and brain interactions. Demonstrates advances in the understanding of the pathophysiology of gastrointestinal and liver diseases.

Blanco s Overview of Alpha 1 Antitrypsin Deficiency

Blanco s Overview of Alpha 1 Antitrypsin Deficiency Book
Author : Ignacio Blanco
Publisher : Academic Press
Release : 2017-04-28
ISBN : 0128095415
Language : En, Es, Fr & De

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Book Description :

Blanco’s Overview of Alpha-1 Antitrypsin Deficiency: History, Biology, Pathophysiology, Related Diseases, Diagnosis, and Treatment is a robust introduction to topics associated with Alpha-1 Antitrypsin Deficiency (AATD). Included are topics ranging from the history of the disease, biology, pathophysiology, related diseases, including the two major manifestations of the disease (liver disease and lung disease), and diagnosis and treatment. The book addresses the need for the amalgamation of current and novel concepts and practices in the field of AATD. AATD is under-recognized in the medical community and, as a result, it is underdiagnosed. The book provides increased awareness and understanding of the condition to improve diagnosis rates and enhance patient care. This book is an essential tool and reference, beneficial to clinicians who screen and treat AATD patients, as well as research scientists working in the AATD field at junior and senior levels. Presents the fundamental theoretical and practical aspects of Alpha-1 Antitrypsin Deficiency (AATD) based on scientific evidence Provides evidence to show that AATD is a rarely diagnosed condition, rather than a rare condition Contains current research and future perspectives from Dr. Ignacio Blanco, a worldwide expert in the field of alpha-1 antitrypsin and lung and liver disease associated with the deficiency of this antiprotease Provides resources to current registries and patient associations

Liver Cirrhosis From Pathophysiology to Disease Management

Liver Cirrhosis  From Pathophysiology to Disease Management Book
Author : J. Bosch,Andrew Burroughs,F. Lammert,D. Lebrec,Tilman Sauerbruch
Publisher : Springer
Release : 2008-05-29
ISBN : 9781402086557
Language : En, Es, Fr & De

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Book Description :

The International Falk Symposium 162 in Dresden is a good example for the promises of history. Sixty years after the misery of the Second World War and the destruction of Dresden and 20 years after a long and threatening Cold War, scientists from more than 50 nations across the world met in a wonderfully reconstructed city to discuss a series of key lectures on the pathophysiology and clinical management of liver cirrhosis. Liver cirrhosis is a leading cause of morbidity and mortality worldwide. It is the fifth most common cause of death between the age of 25 and 45 years. To date, it is still not possible to inhibit or revert progression of cirrhosis in most patients. Accordingly, clinicians primarily deal with the various complications of cirrhosis, while liver transplantation is only available for selected patients. There has been tremendous progress in the understanding of liver fibrosis and cirrhosis since the last Falk Symposium devoted to this topic in 2000.

Porth Pathophysiology

Porth Pathophysiology Book
Author : Charlotte Pooler
Publisher : Lippincott Williams & Wilkins
Release : 2009-10-01
ISBN : 1605477818
Language : En, Es, Fr & De

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Book Description :

The well respected textbook Pathophysiology: Concepts of Altered Health States has now been fully adapted for Canadian undergraduate nursing and health professions students. Like the original text, this Canadian edition includes a review of anatomy and physiology and treatment information for commonly occurring disease states. Pediatric, geriatric, and pregnancy deviations are integrated throughout and highlighted with icons for easy identification. Canadian content includes Canadian healthcare statistics regarding incidence; cultural variations, with a focus on native population and largest immigrant populations; Canadian research and researchers; Canadian treatment protocols and guidelines; and commonly occurring disease concerns based on Canadian statistics.

Liver Anesthesiology and Critical Care Medicine

Liver Anesthesiology and Critical Care Medicine Book
Author : Gebhard Wagener
Publisher : Springer
Release : 2018-04-11
ISBN : 3319642987
Language : En, Es, Fr & De

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Book Description :

Providing anesthesiology for liver surgery and especially liver transplantation is highly complex and requires profound expertise in the physiology and pathophysiology of liver disease. This new edition incorporates the latest information in the field and remains the only available book on the topic. It focuses on the practical aspect of liver anesthesiology and critical care, while providing a comprehensive and in depth summary of the knowledge in this field. Most liver transplant centers now have dedicated teams providing anesthesia care during liver transplantations. In the last years there has been a substantial increase in knowledge and improvement in techniques in anesthesiology and critical care of patients undergoing liver surgery and transplant patients. Liver Anesthesiology and Critical Care Medicine, 2nd Edition includes new chapters on chronic liver failure and hepatic cirrhosis, preoperative risk assessment, evidence in liver anesthesiology, the splanchnic and systemic circulation in liver disease and a special focus on analgesia for liver resection including regional techniques. Written for anesthesiologists and critical care physicians caring for patients undergoing liver surgery and transplantation, this book proves to be an essential companion and review book as the number of liver surgeries with higher complexity continue to increase.

MacSween s Pathology of the Liver E Book

MacSween s Pathology of the Liver E Book Book
Author : Alastair D. Burt,Linda D. Ferrell,Stefan G Hubscher
Publisher : Elsevier Health Sciences
Release : 2017-05-22
ISBN : 0323508693
Language : En, Es, Fr & De

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Book Description :

Since its first publication more than 35 years ago, MacSween’s Pathology of the Liver, by Drs. Alastair D. Burt, Linda D. Ferrell, and Stefan G. Hübscher, has established itself as the definitive reference on liver pathology. The 7th Edition continues the tradition of excellence with more than 1,000 high-quality illustrations, coverage of the new and emerging diagnostic applications and techniques that pathologists must be familiar with, an up-to-date review of drug-induced injury, and much more. A must-have for every surgical pathologist, MacSween’s remains the most authoritative and comprehensive book in its field. Provides comprehensive, state-of-the-art coverage of all malignant and benign hepatobiliary disorders from an international "who’s who" in the field. Helps you quickly recognize the wide variety of liver appearances that result from infections, tumors, and tumor-like lesions, as well as organ damage caused by drugs and toxins. Features 1,000+ full-color illustrations that provide a complete visual guide to each tumor or tumor-like lesion and assist in the recognition and diagnosis of any tissue sample you’re likely to encounter. Incorporates relevant data from ancillary techniques (immunohistochemistry, cytogenetics, and molecular genetics), giving you the tools required to master the latest breakthroughs in diagnostic technology. Includes an updated chapter on mechanisms of liver disease, including coverage of regression and remodeling of disease and new information on next generation sequencing; an up-to-date review of drug-induced injury, including the effects of herbal and alternative medicines.

Pathophysiology

Pathophysiology Book
Author : Carie Ann Braun,Cindy Miller Anderson
Publisher : Lippincott Williams & Wilkins
Release : 2007
ISBN : 9780781762502
Language : En, Es, Fr & De

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Book Description :

This pathophysiology text offers a unique conceptual approach that facilitates learning by viewing pathophysiology as health care professionals do. Students will learn about general mechanisms of disease or alterations in human function—such as immune alterations or altered nutrition—and apply these processes to specific conditions. Chapters focus on fifteen core concepts of altered human function, selected by analyzing and clustering health conditions with high prevalence, incidence, and severity. Unlike a traditional systems-based approach, this novel approach shows how most diseases involve multiple body systems. A bound-in CD-ROM includes animations and an interactive game. Faculty resources include lesson plans, PowerPoint slides, additional case studies, and student assignment worksheets.

Hepatic Circulation

Hepatic Circulation Book
Author : W. Wayne Lautt
Publisher : Morgan & Claypool Publishers
Release : 2009-11-17
ISBN : 1615040099
Language : En, Es, Fr & De

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Book Description :

The Hepatic circulation is unique among vascular beds. The most obvious unique features include the dual vascular supply; the mechanism of intrinsic regulation of the hepatic artery (the hepatic arterial buffer response); the fact that portal blood flow, supplying two thirds of liver blood flow, is not controlled directly by the liver; the fact that 20% of the cardiac output rushes through the most vascularized organ in the body, driven by a pressure gradient of only a few millimeters of mercury; the extremely distensible capacitance and venous resistance sites; the unidirectional acinar blood flow that regulates parenchymal cell metabolic specialization; and the high concentration of macrophagic (Kupffer) cells filtering the blood. The liver is the only organ reported to have regional blood flow monitored by the autonomic nervous system. This mechanism, when dysfunctional, accounts for the hepatorenal syndrome and offers a mechanistic therapeutic target to treat this syndrome. The trigger for liver regeneration is dependent on hepatic hemodynamics so that chronic liver blood flow regulates liver cell mass. In severe liver disease, the whole body circulation is reorganized, by forming portacaval shunts, to accommodate the increased intrahepatic venous resistance. These shunts protect the venous drainage of the splanchnic organs but lead to loss of major regulatory roles of the liver. The development of knowledge of the hepatic vasculature is presented from a historical perspective with modern concepts summarized based on the perspective of the author's four decades of devotion to this most marvelous of organs. Table of Contents: Acknowledgements / Historical Perspectives / Overview / Fluid Exchange / Capacitance / Resistance in the Hepatic Artery / Resistance in the Venous System / Fetal and Neonatal Hepatic Circulation / In Vivo Pharmacodynamic Approaches / Nitric Oxide / Adenosine / Hepatic Nerves / Hepatic Circulation and Toxicology / Hepatorenal Syndrome / Integrative Hepatic Response to Hemorrhage / Blood Flow Regulation of Hepatocyte Proliferation / Multiple Mechanisms Maintaining a Constant Hepatic Blood Flow to Liver Mass Ratio / Pathopharmacology and Repurposing Drugs as a Research Strategy / References

Fibrosis and Inflammation in Tissue Pathophysiology

Fibrosis and Inflammation in Tissue Pathophysiology Book
Author : Elvira Forte,Isotta Chimenti,Gonzalo del Monte-Nieto,Susanne Sattler
Publisher : Frontiers Media SA
Release : 2022-02-23
ISBN : 2889744973
Language : En, Es, Fr & De

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Book Description :

Download Fibrosis and Inflammation in Tissue Pathophysiology book written by Elvira Forte,Isotta Chimenti,Gonzalo del Monte-Nieto,Susanne Sattler, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Basic Pathophysiology

Basic Pathophysiology Book
Author : Maureen Wimberly Groër,Maureen E. Shekleton
Publisher : Unknown
Release : 1979
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Basic Pathophysiology book written by Maureen Wimberly Groër,Maureen E. Shekleton, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Variceal Hemorrhage

Variceal Hemorrhage Book
Author : Roberto de Franchis,Alessandra Dell’Era
Publisher : Springer Science & Business Media
Release : 2014-01-25
ISBN : 1493900021
Language : En, Es, Fr & De

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Book Description :

Variceal Hemorrhage provides an update of the evidence concerning several aspects of variceal hemorrhage. The book features new information on natural history, diagnosis of esophageal varices, assessment of the risk of bleeding and identification of high risk groups and patients who may benefit or be harmed from different treatments. The volume also presents a critical analysis of the different steps in the management of acute variceal bleeding. Authored by the most prominent world experts in their areas of expertise, Variceal Hemorrhage serves as a very useful reference for gastroenterologists, GI surgeons, residents in internal medicine and physicians dealing with and interested in the different aspects of this severe medical emergency.

Pathophysiology for Nurses at a Glance

Pathophysiology for Nurses at a Glance Book
Author : Muralitharan Nair,Ian Peate
Publisher : John Wiley & Sons
Release : 2015-02-24
ISBN : 1118746058
Language : En, Es, Fr & De

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Book Description :

Everything you need to know about Pathophysiology... at a Glance! From the publishers of the market-leading at a Glance series, and from the authors of the successful Fundamentals of Applied Pathophysiology textbook comes the ideal revision guide for all the key diseases and conditions that nursing and healthcare students need to be aware of. Combining superb illustrations with accessible and informative text, this book is perfect for all nursing and healthcare students, and anyone who is looking for an overview of pathophysiology. Pathophysiology for Nurses at a Glance covers all the key diseases and disease processes affecting each body system, and key concepts encountered from the start of the pre-registration nursing or healthcare course. Key features: Superbly illustrated, with full colour illustrations throughout Written specifically for nursing and healthcare students with all the information they need Self-assessment questions provided for each chapter Pathophysiology for Nurses at a Glance is ideal for nursing and healthcare students as well as qualified practitioners, providing a comprehensive yet accessible overview of human pathophysiology.