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Lead Compounds From Medicinal Plants For The Treatment Of Cancer

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Lead Compounds from Medicinal Plants for the Treatment of Cancer

Lead Compounds from Medicinal Plants for the Treatment of Cancer Book
Author : Christophe Wiart
Publisher : Academic Press
Release : 2013
ISBN : 0123983711
Language : En, Es, Fr & De

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Book Description :

Lead Compounds from Medicinal Plants for the Treatment of Cancer is the first volume in the series, Pharmaceutical Leads from Medicinal Plants. The plant species described in this reference have been carefully selected based on pharmacological evidence and represent today's most promising sources of natural products for the discovery of anti-cancer drugs. Containing references to primary source material, over a hundred botanical illustrations, a table of chemical structures and much more, this book is an essential starting point for cancer researchers and those involved in anti-cancer drug discovery helping you identify the best novel lead molecules for further anti-cancer drug development. Provides a compilation of hundreds of medicinal plants from Europe, Asia, North and South America and Africa that contain prominent lead candidates for anti-cancer drug discovery Contains primary source references and hundreds of the most relevant citations from the current literature for additional research Offers cancer researchers and pharmaceutical scientists valuable tools such as chemical structures and promising pharmacological data to help them select the novel lead compounds that will best aid drug discovery.

Plant Natural Products for Human Health

Plant Natural Products for Human Health Book
Author : Chun-Tao Che,Hongjie Zhang
Publisher : MDPI
Release : 2019-03-21
ISBN : 3038977128
Language : En, Es, Fr & De

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Book Description :

Plants have served mankind as an important source of foods and medicines. While we all consume plants and their products for nutritional support, a majority of the world population also rely on botanical remedies to meet their health needs, either as their own “traditional medicine” or as “complementary and alternative medicine”. From a pharmaceutical point of view, many compounds obtained from plant sources have long been known to possess bio/pharmacological activities, and historically, plants have yielded many important drugs for human use, from morphine discovered in the early nineteenth century to the more recent paclitaxel and artemisinin. Today, we are witnessing a global resurgence in interest and use of plant-based therapies and botanical products, and natural products remain an important and viable source of lead compounds in many drug discovery programs. This Special Issue on “Plant Natural Products for Human Health” compiles a series of scientific reports to demonstrate the medicinal potentials of plant natural products. It covers a range of disease targets, such as diabetes, inflammation, cancer, neurological disease, cardiovascular disease, liver damage, bacterial, and fungus infection and malarial. These papers provide important insights into the current state of research on drug discovery and new techniques. It is hoped that this Special Issue will serve as a timely reference for researchers and scholars who are interested in the discovery of potentially useful molecules from plant sources for health-related applications.

Anticancer Plants Mechanisms and Molecular Interactions

Anticancer Plants  Mechanisms and Molecular Interactions Book
Author : Mohd Sayeed Akhtar,Mallappa Kumara Swamy
Publisher : Springer
Release : 2018-07-03
ISBN : 9811084173
Language : En, Es, Fr & De

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Book Description :

This book summarizes the application of plant derived anticancer compounds as chemopreventives to treat several cancer types, focusing on the molecular mechanisms of action of phytocompounds and providing an overview of the basic processes at the cellular and molecular level that are involved in the progression of the cancer and can be employed in targeted preventive therapies. In addition, it highlights the development of novel anticancer drugs from plant sources using bioinformatics approaches. The compiled chapter data aids readers understanding of issues related to bioavailability, toxic effects and mechanisms of action of phytocompounds, and helps them identify the leads and utilize them against various cancer types effectively. Furthermore, it promotes the use of bioinformatics tools in medicinal plants to expedite their use in plant breeding programs to develop molecular markers to distinguish disease subtypes and predicting mutation, which in turn improves cancer diagnosis and prognosis, and to develop new lead compounds computationally. The book provides scientific verifications of plant compounds mechanisms of action against various cancers and offers useful information for students, teachers, and healthcare professionals involved in drug discovery, and clinical and therapeutic research.

Phytochemicals as Lead Compounds for New Drug Discovery

Phytochemicals as Lead Compounds for New Drug Discovery Book
Author : Chukwuebuka Egbuna,Shashank Kumar,Jonathan C. Ifemeje,Shahira M. Ezzat,Saravanan Kaliyaperumal
Publisher : Elsevier
Release : 2019-09-07
ISBN : 0128178914
Language : En, Es, Fr & De

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Book Description :

Phytochemicals as Lead Compounds for New Drug Discovery presents complete coverage of the recent advances in the discovery of phytochemicals from medicinal plants as models to the development of new drugs and chemical entities. Functional bioactive compounds of plant origin have been an invaluable source for many human therapeutic drugs and have played a major role in the treatment of diseases around the world. These compounds possess enormous structural and chemical diversity and have led to many important discoveries. This book presents fundament concepts and factors affecting the choice for plant-based products, as well as recent advances in computer-aided drug discovery and FDA drug candidacy acceptance criteria. It also details the various bioactive lead compounds and molecular targets for a range of life-threatening diseases including cancer, diabetes, and neurodegenerative diseases. Written by a global team of experts, Phytochemicals as Lead Compounds for New Drug Discovery is an ideal resource for drug developers, phytochemists, plant biochemists, food and medicinal chemists, nutritionists and toxicologists, chemical ecologists, taxonomists, analytical chemists, and other researchers in those fields. It will also be very valuable to professors, students, and researchers in this domain. Presents fundamental concepts and factors affecting choice for plant-based products Details the FDA drug candidacy acceptance criteria, including bottlenecks and way forward Highlights recent advances in computational-based drug discovery Focuses on the discovery of new drugs and potential druggable targets for the treatment of chronic diseases of world importance

Recent Trends in Medicinal Plants Research

Recent Trends in Medicinal Plants Research Book
Author : Anonim
Publisher : Academic Press
Release : 2012-11-13
ISBN : 0123947995
Language : En, Es, Fr & De

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Book Description :

Plants and other living organisms have great potential to treat human disease. There are two distinct types of biomedical research that seek to develop this potential. One type of research explores the value of medicinal plants as traditionally used and studies of these plants have the potential to determine which plants are most potent, optimize dosages and dose forms, and identify safety risks. Another type of research uses bioassays to identify single molecules from plants that have interesting bioactivities in isolation and might be useful lead compounds for the development of pharmaceutical drugs. This new volume of Advances in Botanical Research covers the recent trends in Medicinal Plants Research over 11 chapters. Topics that are covered include Development of Drugs from Plants – Regulation and Evaluation, Chinese Herbal Medicines for Rheumatoid Arthritis, and Taxol, camptothecin and beyond for cancer therapy. Covers the recent trends in medicinal plants research over 11 chapters Topics that are covered include Development of Drugs from Plants – Regulation and Evaluation, Chinese Herbal Medicines for Rheumatoid Arthritis, and Taxol, camptothecin and beyond for cancer therapy

Lead Molecules from Natural Products

Lead Molecules from Natural Products Book
Author : Anonim
Publisher : Elsevier
Release : 2006-07-07
ISBN : 9780080459332
Language : En, Es, Fr & De

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Book Description :

Lead Molecules from Natural Products: Discovery and New Trends provides the reader with a thorough overview of current discoveries and trends in Natural Products research. This book consists of 22 chapters from well known scientists all over the world, with topics ranging from Natural Product Chemistry and Phytochemistry in their most basic form, to Molecular Biology and in silico drug design. Contributors describe their own laboratory experiences, revealing their findings, the legal issues encountered. The chapters, all of equally high quality, summarize years of extensive research in each area, and provide insight in the new themes of natural product research. The information will help to predict promising leads, useful for physicians in the treatment of different diseases and disease manifestations. * Explains the effects of plant extracts on gene expression profiling. * Details medicinal plant research from around the world * Explores a variety of medicinal uses of plants from traditional remedies, to anti-cancer agents and anti-salmonella agents.

Classic Botanical Reprints 227 238

Classic Botanical Reprints   227 238 Book
Author : Anonim
Publisher : Unknown
Release : 199?
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Classic Botanical Reprints 227 238 book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Medicinal and Economic Plants of Nupeland

Medicinal and Economic Plants of Nupeland Book
Author : Abdullahi Mann,Muhammad Gbate,Abdulkadir Nda Umar
Publisher : Unknown
Release : 2003
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Medicinal and Economic Plants of Nupeland book written by Abdullahi Mann,Muhammad Gbate,Abdulkadir Nda Umar, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Multitherapic medicinal spiceal plants

Multitherapic medicinal   spiceal plants Book
Author : Karan Singh,Mohan Lal Jakhar,Dhirendra Singh
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Multitherapic medicinal spiceal plants book written by Karan Singh,Mohan Lal Jakhar,Dhirendra Singh, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Ethnopharmacology Volume I

Ethnopharmacology   Volume I Book
Author : Elaine Elisabetsky,Nina L. Etkin
Publisher : EOLSS Publications
Release : 2009-10-29
ISBN : 1905839960
Language : En, Es, Fr & De

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Book Description :

Ethnopharmacology is a component of Encyclopedia of Biological, Physiological and Health Sciences in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. Ethnopharmacology is the scientific study correlating ethnic groups, their health, and how it relates to their physical habits and methodology in creating and using medicines. This Theme on Ethnopharmacology presents the field as an amalgam of perspectives, primarily those of pharmacology, pharmacognosy, anthropology, and botany. It highlights the uniquely biocultural perspective on ethnopharmacology offered by medical anthropology, which underscores that health and healing are culturally constructed and socially negotiated. The definition of ethnopharmacology that frames this volume is: the study of indigenous medical systems that connects the ethnography of health and healing with the physiological relevance of its medical practices. The history of botanical medicines is traced from primate self-medication to contributions to biomedicine. The methods of ethnopharmacologic inquiry are presented from pharmacologic, ecological, ethnographic, data management, and ethical perspectives. Chapters are devoted to plants used in the treatment of specific disorders: cancer, parasitic infection, AIDS, inflammation, diabetes, and cardiovascular and neurodegenerative disorders. The important role that plant medicines play in the developing world is revealed in discussion of ritual and ceremony, safety issues, health care, and biodiversity. These two volumes are aimed at the following a wide spectrum of audiences from the merely curious to those seeking in-depth knowledge: University and College students Educators, Professional practitioners, Research personnel and Policy analysts, managers, and decision makers and NGOs.

The Practice of Medicinal Chemistry

The Practice of Medicinal Chemistry Book
Author : C. G. Wermuth
Publisher : Unknown
Release : 1996
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This book collects in one single volume, the practical aspects of Medicinal Chemistry, seen from a chemical point of view, including the wealth of information which chemists accumulate over a career, but generally is never organized and presented in a coherent form in print. Emphasis is given to how medicinal chemists conduct their search for, and design of, new drug entities. In contrast to other books on the market, it focuses on the chemistry, rather than pharmacological concepts or description of the various therapeutic classes of drugs. It should become a standard reference on the tools available to medicinal chemists when designing new drugs. Key Features * These aspects are covered by: * Specific chapters devoted to the discovery of new lead compounds, including combinatorial chemistry * Clearly written chapters on modern topics such as stereochemical aspects of drug action, the use of X-ray structures of receptors and enzymes in drug discovery, and the contribution of molecular biology to drug discovery * Guidelines and operational strategems allowing identification of the portions of the molecule which are important for potency * The particular emphasis given to the three-dimensional aspects of the drug-receptor interactions, to the design of peptidomimetic drugs and to the control of the agonist-antagonist transition * Chemical solutions to solubility and to formulation problems These sections cover perhaps the most neglected areas in medicinal chemistry books * Development of new drugs: legal and economic aspects, constitutes another important area in which chemists are almost wholly self taught following their entry into industry

Phytomedicines in Malaria and Sexually Transmitted Diseases

Phytomedicines in Malaria and Sexually Transmitted Diseases Book
Author : Clement O. Adewunmi,Simeon K. Adesina
Publisher : Unknown
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Phytomedicines in Malaria and Sexually Transmitted Diseases book written by Clement O. Adewunmi,Simeon K. Adesina, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Phytochemicals

Phytochemicals Book
Author : Venketeshwer Rao,Leticia Rao
Publisher : BoD – Books on Demand
Release : 2015-09-30
ISBN : 9535121707
Language : En, Es, Fr & De

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Book Description :

Global dietary recommendations emphasize the consumption of plant-based foods for the prevention and management of chronic diseases. Plants contain many biologically active compounds referred to as phytochemicals or functional ingredients. These compounds play an important role in human health. Prior to establishing the safety and health benefits of these compounds, they must first be isolated, purified, and their physico-chemical properties established. Once identified, their mechanisms of actions are studied. The chapters are arranged in the order from isolation, purification and identification to in vivo and clinical studies, there by covering not only the analytical procedures used but also their nutraceutical and therapeutic properties.

Natural Antimicrobial Components Isolated from Yerba Mate Ilex Paraguariensis Leaves

Natural Antimicrobial Components Isolated from Yerba Mate   Ilex Paraguariensis  Leaves Book
Author : Tipparat Hongpattarakere
Publisher : Unknown
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Natural Antimicrobial Components Isolated from Yerba Mate Ilex Paraguariensis Leaves book written by Tipparat Hongpattarakere, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Mini Reviews in Medicinal Chemistry

Mini Reviews in Medicinal Chemistry Book
Author : Anonim
Publisher : Unknown
Release : 2009
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Mini Reviews in Medicinal Chemistry book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Biological Agriculture Horticulture

Biological Agriculture   Horticulture Book
Author : Anonim
Publisher : Unknown
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Biological Agriculture Horticulture book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Histidine tyrosine Side Chain Bonding

Histidine tyrosine Side Chain Bonding Book
Author : Yakira Rodríguez Landaverry
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Histidine tyrosine Side Chain Bonding book written by Yakira Rodríguez Landaverry, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Compositae Newsletter

Compositae Newsletter Book
Author : Anonim
Publisher : Unknown
Release : 1996
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Compositae Newsletter book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Human Medicinal Agents from Plants

Human Medicinal Agents from Plants Book
Author : A. Douglas Kinghorn,Manuel F. Balandrin,American Chemical Society. Meeting
Publisher : Amer Chemical Society
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

From a symposium at the April 1992 meeting of the American Chemical Society in San Francisco, 22 papers explore the current role and importance of plant-derived natural products in the discovery and development of drugs, in anticancer and cancer chemopreventive agents, in anti-infective and antimicrobial chemotherapeutic agents, and in the potential for products with multiple biological activities. Annotation copyright by Book News, Inc., Portland, OR

The Avery Complete Guide to Medicines

The Avery Complete Guide to Medicines Book
Author : Ian Morton,Judith Hall
Publisher : Avery Publishing Group
Release : 2001
ISBN : 9781583331057
Language : En, Es, Fr & De

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Book Description :

Featuring more than ten thousand entries, this comprehensive medical reference provides detailed information on what medicines are, their purpose, dosages, potential side effects, contraindications, and drug and food interactions for generic and brand-name medications, along with information on ailments, herbal remedies, and nutritional supplements. Original.