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Landmark Experiments In Molecular Biology

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Landmark Experiments in Molecular Biology

Landmark Experiments in Molecular Biology Book
Author : Michael Fry
Publisher : Academic Press
Release : 2016-06-10
ISBN : 012802108X
Language : En, Es, Fr & De

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Book Description :

Landmark Experiments in Molecular Biology critically considers breakthrough experiments that have constituted major turning points in the birth and evolution of molecular biology. These experiments laid the foundations to molecular biology by uncovering the major players in the machinery of inheritance and biological information handling such as DNA, RNA, ribosomes, and proteins. Landmark Experiments in Molecular Biology combines an historical survey of the development of ideas, theories, and profiles of leading scientists with detailed scientific and technical analysis. Includes detailed analysis of classically designed and executed experiments Incorporates technical and scientific analysis along with historical background for a robust understanding of molecular biology discoveries Provides critical analysis of the history of molecular biology to inform the future of scientific discovery Examines the machinery of inheritance and biological information handling

Landmark Papers in Cell Biology

Landmark Papers in Cell Biology Book
Author : Joseph G. Gall,J. Richard McIntosh
Publisher : CSHL Press
Release : 2001
ISBN : 9780879696023
Language : En, Es, Fr & De

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Book Description :

Annotation Contains 42 seminal papers illustrating advances in cell biology, along with brief commentaries that place the papers in historical and intellectual context. All papers are studies of eukaryotes, and are grouped according to themes of genome organization and replication, transcription, nuclear envelope and nuclear import, mitosis and cell cycle control, cell membrane and extracellular matrix, protein synthesis and membrane traffic, and cytoskeleton. Lacks a subject index. Gall teaches embryology at the Carnegie Institution. McIntosh teaches cell biology at the University of Colorado. Annotation c. Book News, Inc., Portland, OR (booknews.com).

Molecular Cell Biology

Molecular Cell Biology Book
Author : Harvey F. Lodish,Arnold Berk,Chris A. Kaiser
Publisher : W.H. Freeman
Release : 2012
ISBN : 9781464109812
Language : En, Es, Fr & De

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Book Description :

With its acclaimed authors, cutting-edge content, emphasis on medical relevance and landmark experiments, Molecular Cell Biology is an impeccable textbook. Updated throughout, the seventh edition features new co-author Angelika Amon, a completely rewritten chapter on the Cell Cycle and significant updates to experimental techniques.

Molecular Biology of the Cell

Molecular Biology of the Cell Book
Author : Bruce Alberts
Publisher : Unknown
Release : 2004
ISBN : 9780815332183
Language : En, Es, Fr & De

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Book Description :

Download Molecular Biology of the Cell book written by Bruce Alberts, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Meselson Stahl and the Replication of DNA

Meselson  Stahl  and the Replication of DNA Book
Author : Frederic Lawrence Holmes
Publisher : Yale University Press
Release : 2008-10-01
ISBN : 0300129661
Language : En, Es, Fr & De

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Book Description :

In 1957 two young scientists, Matthew Meselson and Frank Stahl, produced a landmark experiment confirming that DNA replicates as predicted by the double helix structure Watson and Crick had recently proposed. It also gained immediate renown as a “most beautiful” experiment whose beauty was tied to its simplicity. Yet the investigative path that led to the experiment was anything but simple, Frederic L. Holmes shows in this masterful account of Meselson and Stahl’s quest. This book vividly reconstructs the complex route that led to the Meselson-Stahl experiment and provides an inside view of day-to-day scientific research--its unpredictability, excitement, intellectual challenge, and serendipitous windfalls, as well as its frustrations, unexpected diversions away from original plans, and chronic uncertainty. Holmes uses research logs, experimental films, correspondence, and interviews with the participants to record the history of Meselson and Stahl’s research, from their first thinking about the problem through the publication of their dramatic results. Holmes also reviews the scientific community’s reception of the experiment, the experiment’s influence on later investigations, and the reasons for its reputation as an exceptionally beautiful experiment.

The Double Helix

The Double Helix Book
Author : James D. Watson
Publisher : Simon and Schuster
Release : 2011-08-16
ISBN : 0743219171
Language : En, Es, Fr & De

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Book Description :

The classic personal account of Watson and Crick’s groundbreaking discovery of the structure of DNA, now with an introduction by Sylvia Nasar, author of A Beautiful Mind. By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only twenty-four, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science’s greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries. With humility unspoiled by false modesty, Watson relates his and Crick’s desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work.

Molecular Biology of RNA

Molecular Biology of RNA Book
Author : David Elliott,Michael Ladomery
Publisher : Oxford University Press
Release : 2017-01-31
ISBN : 019107103X
Language : En, Es, Fr & De

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Book Description :

RNA plays a central, and until recently, somewhat underestimated role in the genetics underlying all forms of life on earth. This versatile molecule not only plays a crucial part in the synthesis of proteins from a DNA template, but is also intrinsically involved in the regulation of gene expression, and can even act as a catalyst in the form of a ribozyme. This latter property has led to the hypothesis that RNA - rather than DNA - could have played an essential part in the origin of life itself. This landmark text provides a systematic overview of the exciting and rapidly moving field of RNA biology. Key pioneering experiments, which provided the underlying evidence for what we now know, are described throughout, while the relevance of the subject to human disease is highlighted via frequent boxes. For the second edition of Molecular Biology of RNA, more introductory material has been incorporated at the beginning of the text, to aid students studying the subject for the first time. Throughout the text, new material has been included - particularly in relation to RNA binding domains, non-coding RNAs, and the connection between RNA biology and epigenetics. Finally, a new closing chapter discusses how exciting new technologies are being used to explore current topical areas of research.

Advanced Methods in Molecular Biology and Biotechnology

Advanced Methods in Molecular Biology and Biotechnology Book
Author : Khalid Z. Masoodi,Sameena Maqbool Lone,Rovidha Saba Rasool
Publisher : Academic Press
Release : 2020-11-10
ISBN : 012824450X
Language : En, Es, Fr & De

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Book Description :

Advanced Methods in Molecular Biology and Biotechnology: A Practical Lab Manual is a concise reference on common protocols and techniques for advanced molecular biology and biotechnology experimentation. Each chapter focuses on a different method, providing an overview before delving deeper into the procedure in a step-by-step approach. Techniques covered include genomic DNA extraction using cetyl trimethylammonium bromide (CTAB) and chloroform extraction, chromatographic techniques, ELISA, hybridization, gel electrophoresis, dot blot analysis and methods for studying polymerase chain reactions. Laboratory protocols and standard operating procedures for key equipment are also discussed, providing an instructive overview for lab work. This practical guide focuses on the latest advances and innovations in methods for molecular biology and biotechnology investigation, helping researchers and practitioners enhance and advance their own methodologies and take their work to the next level. Explores a wide range of advanced methods that can be applied by researchers in molecular biology and biotechnology Features clear, step-by-step instruction for applying the techniques covered Offers an introduction to laboratory protocols and recommendations for best practice when conducting experimental work, including standard operating procedures for key equipment

The Transforming Principle

The Transforming Principle Book
Author : Maclyn McCarty
Publisher : W. W. Norton & Company
Release : 1986
ISBN : 9780393304503
Language : En, Es, Fr & De

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Book Description :

Tells how research aimed at a cure for pneumonia, based on the determination of how an inactive bacterium became active, led to an understanding of the role of DNA

Molecular Cell Biology

Molecular Cell Biology Book
Author : Harvey Lodish
Publisher : W.H. Freeman
Release : 2000
ISBN : 9780716730538
Language : En, Es, Fr & De

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Book Description :

With its acclaimed author team, cutting-edge content, emphasis on medical relevance, and coverage based on landmark experiments, "Molecular Cell Biology" has justly earned an impeccable reputation as an authoritative and exciting text. The new Sixth Edition features two new coauthors, expanded coverage of immunology and development, and new media tools for students and instructors.

Genetics and Molecular Biology

Genetics and Molecular Biology Book
Author : Robert F. Schleif
Publisher : Unknown
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

In the first edition of Genetics and Molecular Biology, renowned researcher and award-winning teacher Robert Schleif produced a unique and stimulating text that was a notable departure from the standard compendia of facts and observations. Schleif's strategy was to present the underlying fundamental concepts of molecular biology with clear explanations and critical analysis of well-chosen experiments. The result was a concise and practical approach that offered students a real understanding of the subject. This second edition retains that valuable approach--with material thoroughly updated to include an integrated treatment of prokaryotic and eukaryotic molecular biology. Genetics and Molecular Biology is copiously illustrated with two-color line art. Each chapter includes an extensive list of important references to the primary literature, as well as many innovative and thought-provoking problems on material covered in the text or on related topics. These help focus the student's attention of a variety of critical issues. Solutions are provided for half of the problems. Praise for the first edition: "Schleif's Genetics and Molecular Biology... is a remarkable achievement. It is an advanced text, derived from material taught largely to postgraduates, and will probably be thought best suited to budding professionals in molecular genetics. In some ways this would be a pity, because there is also gold here for the rest of us... The lessons here in dealing with the information explosion in biology are that an ounce of rationale is worth a pound of facts and that, for educational value, there is nothing to beat an author writing about stuff he knows from theinside."--Nature. "Schleif presents a quantitative, chemically rigorous approach to analyzing problems in molecular biology. The text is unique and clearly superior to any currently available."--R.L. Bernstein, San Francisco State University. "The greatest strength is the author's ability to challenge the student to become involved and get below the surface."--Clifford Brunk, UCLA

Molecular Machines

Molecular Machines Book
Author : Giovanni Zocchi
Publisher : Princeton University Press
Release : 2018-07-10
ISBN : 1400890063
Language : En, Es, Fr & De

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Book Description :

Molecular Machines presents a dynamic new approach to the physics of enzymes and DNA from the perspective of materials science. Unified around the concept of molecular deformability—how proteins and DNA stretch, fold, and change shape—this book describes the complex molecules of life from the innovative perspective of materials properties and dynamics, in contrast to structural or purely chemical approaches. It covers a wealth of topics, including nonlinear deformability of enzymes and DNA; the chemo-dynamic cycle of enzymes; supra-molecular constructions with internal stress; nano-rheology and viscoelasticity; and chemical kinetics, Brownian motion, and barrier crossing. Essential reading for researchers in materials science, engineering, and nanotechnology, the book also describes the landmark experiments that have established the materials properties and energy landscape of large biological molecules. Molecular Machines is also ideal for the classroom. It gives graduate students a working knowledge of model building in statistical mechanics, making it an essential resource for tomorrow's experimentalists in this cutting-edge field. In addition, mathematical methods are introduced in the bio-molecular context—for example, DNA conformational transitions are used to illustrate the transfer matrix formalism. The result is a generalized approach to mathematical problem solving that enables students to apply their findings more broadly. Molecular Machines represents the next leap forward in nanoscience, as researchers strive to harness proteins, enzymes, and DNA as veritable machines in medicine, technology, and beyond.

Essential Cell Biology

Essential Cell Biology Book
Author : Bruce Alberts,Dennis Bray,Karen Hopkin,Alexander D Johnson,Julian Lewis,Martin Raff,Keith Roberts,Peter Walter
Publisher : Garland Science
Release : 2013-10-15
ISBN : 1317806271
Language : En, Es, Fr & De

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Book Description :

Essential Cell Biology provides a readily accessible introduction to the central concepts of cell biology, and its lively, clear writing and exceptional illustrations make it the ideal textbook for a first course in both cell and molecular biology. The text and figures are easy-to-follow, accurate, clear, and engaging for the introductory student. Molecular detail has been kept to a minimum in order to provide the reader with a cohesive conceptual framework for the basic science that underlies our current understanding of all of biology, including the biomedical sciences. The Fourth Edition has been thoroughly revised, and covers the latest developments in this fast-moving field, yet retains the academic level and length of the previous edition. The book is accompanied by a rich package of online student and instructor resources, including over 130 narrated movies, an expanded and updated Question Bank. Essential Cell Biology, Fourth Edition is additionally supported by the Garland Science Learning System. This homework platform is designed to evaluate and improve student performance and allows instructors to select assignments on specific topics and review the performance of the entire class, as well as individual students, via the instructor dashboard. Students receive immediate feedback on their mastery of the topics, and will be better prepared for lectures and classroom discussions. The user-friendly system provides a convenient way to engage students while assessing progress. Performance data can be used to tailor classroom discussion, activities, and lectures to address students’ needs precisely and efficiently. For more information and sample material, visit http://garlandscience.rocketmix.com/.

Fundamental Molecular Biology 2nd Edition

Fundamental Molecular Biology  2nd Edition Book
Author : Lizabeth A. Allison
Publisher : Wiley Global Education
Release : 2011-10-03
ISBN : 1118209885
Language : En, Es, Fr & De

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Book Description :

Perfect for a single term on Molecular Biology and more accessible to beginning students in the field than its encyclopedic counterparts, Fundamental Molecular Biology provides a distillation of the essential concepts of molecular biology, and is supported by current examples, experimental evidence, an outstanding art program, multimedia support and a solid pedagogical framework. The text has been praised both for its balanced and solid coverage of traditional topics, and for its broad coverage of RNA structure and function, epigenetics and medical molecular biology.

The Black Box of Biology

The Black Box of Biology Book
Author : Michel Morange
Publisher : Unknown
Release : 2020
ISBN : 0674281365
Language : En, Es, Fr & De

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Book Description :

Michel Morange updates the history of molecular biology at a moment when scientists are making big strides in genetic engineering and exploring new avenues, from epigenetics to systems biology. Morange places the latest findings and ideas in historical context, describing in accessible terms how transformative the molecular revolution has been.

Globalization Biosecurity and the Future of the Life Sciences

Globalization  Biosecurity  and the Future of the Life Sciences Book
Author : National Research Council,Institute of Medicine,Board on Global Health,Policy and Global Affairs,Development, Security, and Cooperation,Committee on Advances in Technology and the Prevention of Their Application to Next Generation Biowarfare Threats
Publisher : National Academies Press
Release : 2006-06-07
ISBN : 9780309164757
Language : En, Es, Fr & De

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Book Description :

Biomedical advances have made it possible to identify and manipulate features of living organisms in useful ways--leading to improvements in public health, agriculture, and other areas. The globalization of scientific and technical expertise also means that many scientists and other individuals around the world are generating breakthroughs in the life sciences and related technologies. The risks posed by bioterrorism and the proliferation of biological weapons capabilities have increased concern about how the rapid advances in genetic engineering and biotechnology could enable the production of biological weapons with unique and unpredictable characteristics. Globalization, Biosecurity, and the Future of Life Sciences examines current trends and future objectives of research in public health, life sciences, and biomedical science that contain applications relevant to developments in biological weapons 5 to 10 years into the future and ways to anticipate, identify, and mitigate these dangers.

Recombinant DNA

Recombinant DNA Book
Author : James D. Watson
Publisher : Unknown
Release : 2007-01-01
ISBN : 9781429203128
Language : En, Es, Fr & De

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Book Description :

This text presents an introduction to the concepts and techniques of recombinant DNA research and their dramatic results. It explores core concepts in molecular biology in a contemporary inquiry-based context, building its coverage around the landmark experiments that redefined our understanding of DNA.

Molecular Cell Biology

Molecular Cell Biology Book
Author : Harvey Lodish,David Baltimore
Publisher : W H Freeman & Company
Release : 1995
ISBN : 9780716726746
Language : En, Es, Fr & De

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Book Description :

With its acclaimed author team, cutting-edge content, emphasis on medical relevance, and coverage based on landmark experiments, "Molecular Cell Biology" has justly earned an impeccable reputation as an authoritative and exciting text. The new Sixth Edition features two new coauthors, expanded coverage of immunology and development, and new media tools for students and instructors.

Molecular Cell Biology

Molecular Cell Biology Book
Author : James E. Darnell,Harvey F. Lodish,David Baltimore
Publisher : W.H. Freeman
Release : 1990
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Integrates molecular biology with biochemistry, cell biology, and genetics and applies this to development, immunology, and center.

Phage and the Origins of Molecular Biology

Phage and the Origins of Molecular Biology Book
Author : Cold Spring Harbor Laboratory,Cold Spring Harbor Laboratory of Quantitative Biology,Max Delbrück
Publisher : Unknown
Release : 1966
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This is an expanded edition of the landmark collection of 35 essays by pioneers of molecular biology that was first published in 1966 as a 60th birthday tribute to Max Delbruck. The book was hailed as "[introducing] into the literature of science, for the first time, a self-conscious historical element in which the participants in scientific discovery engage in writing their own chronicle. As such, it is an important document in the history of biology..." (Journal of History of Biology). This new edition includes Gunther Stent's obituary of Max Delbruck, two commentaries on issues raised in the book reprinted from Scientific American and Science, and a new preface in which John Cairns reflects on the book's creation and molecular biology's "age of innocence."