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Laboratory Exercises In Molecular Pathology

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Laboratory Exercises in Molecular Pathology

Laboratory Exercises in Molecular Pathology Book
Author : Jonathon W. Homeister,Gregory J. Tsongalis,William B. Coleman
Publisher : Academic Press
Release : 2017-10-01
ISBN : 9780128006085
Language : En, Es, Fr & De

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Book Description :

Laboratory Exercises in Molecular Pathology is organized by major organ systems and then by disease type. In each exercise, there is a distillation of essential disease-specific information (related to frequency, risk factors, disease manifestations) and a description of disease pathogenesis (molecular and cellular) that is based upon accepted principles from the literature. Further, each exercise is illustrated with (1) gross specimens, (2) microscopic histopathology, (3) immunohistochemistry and/or in situ hybridization (when applicable), (4) laboratory techniques to probe the molecular nature of the pathological lesions, and (5) molecular diagnostics (when applicable). In addition, each exercise contains one or more cases studies to provide students with exposure to the clinical workup of a patient, based upon physical examination findings, traditional pathological analysis, and state-of-the-art molecular assessment. The laboratory techniques included emphasize the dissection of molecular and cellular pathogenesis of the disease in question. Hence, students will see examples of laboratory results that illustrate how pathways were elucidated. Further, the sections on molecular diagnostics illustrate how molecular testing exploits what is known about molecular pathogenesis in a specific disease setting. The manual does not present molecular methods and techniques in isolation; it illustrates how these experimental approaches and applied methodologies can be used to generate meaningful information in the clinical setting. Presents foundational information, examples of gross and microscopic pathology, and examples of molecular approaches and molecular testing all in one resource Offers an ancillary website with videos corresponding to the evaluation of gross specimens, the assessment of microscopic images, and the demonstration of how laboratory techniques are performed Features exercises which contain one or more cases studies to provide students with exposure to the clinical workup of a patient, based upon physical examination findings, traditional pathological analysis, and state-of-the-art molecular assessment Provides case studies which include self-assessment modules and decision trees that allow students to make mistakes and then receive explanations

Diagnostic Molecular Pathology

Diagnostic Molecular Pathology Book
Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Academic Press
Release : 2016-10-05
ISBN : 0128011572
Language : En, Es, Fr & De

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Book Description :

Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing is organized around disease types (genetic disease, infectious disease, neoplastic disease, among others). In each section, the authors provide background on disease mechanisms and describe how laboratory testing is built on knowledge of these mechanisms. Sections are dedicated to general methodologies employed in testing (to convey the concepts reflected in the methods), and specific description of how these methods can be applied and are applied to specific diseases are described. The book does not present molecular methods in isolation, but considers how other evidence (symptoms, radiology or other imaging, or other clinical tests) is used to guide the selection of molecular tests or how these other data are used in conjunction with molecular tests to make diagnoses (or otherwise contribute to clinical workup). In addition, final chapters look to the future (new technologies, new approaches) of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests. Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing contains exercises to test readers on their understanding of how molecular diagnostic tests are utilized and the value of the information that can be obtained in the context of the patient workup. Readers are directed to an ancillary website that contains supplementary materials in the form of exercises where decision trees can be employed to simulate actual clinical decisions. Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis, and classification in the clinical workup of a patient Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for prognostication of disease Features an ancillary website with self-testing exercises where decision trees can be employed to simulate actual clinical decisions Highlights new technologies and approaches of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests

Plant Pathology Concepts and Laboratory Exercises

Plant Pathology Concepts and Laboratory Exercises Book
Author : Bonnie H. Ownley,Robert N. Trigiano
Publisher : CRC Press
Release : 2016-11-03
ISBN : 1498774725
Language : En, Es, Fr & De

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Book Description :

Continuing in the tradition of its predecessors, this new edition combines an informal, easy to read style with a thorough introduction to concepts and terminology of plant pathology. After reviewing fundamental concepts, the book discusses groups of plant pathogens and molecular tools for studying them, pathogen interactions, epidemiology and disease control, and special topics in plant pathology. The book details various disease-causing organisms, including viruses, fungi, prokaryotics, nematodes, and various biotic agents. It also examines various plant-pathogen interactions, molecular attack strategies, extracellular enzymes, host defenses, and disruption of plant function. New in the Third Edition Molecular plant-fungal interactions Expanded treatment of molecular tools Advanced biocontrol concepts How to use and care for microscopes

Molecular Diagnostics

Molecular Diagnostics Book
Author : George P. Patrinos,Wilhelm Ansorge,Phillip B. Danielson
Publisher : Academic Press
Release : 2016-10-27
ISBN : 0128029889
Language : En, Es, Fr & De

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Book Description :

Molecular Diagnostics, Third Edition, focuses on the technologies and applications that professionals need to work in, develop, and manage a clinical diagnostic laboratory. Each chapter contains an expert introduction to each subject that is next to technical details and many applications for molecular genetic testing that can be found in comprehensive reference lists at the end of each chapter. Contents are divided into three parts, technologies, application of those technologies, and related issues. The first part is dedicated to the battery of the most widely used molecular pathology techniques. New chapters have been added, including the various new technologies involved in next-generation sequencing (mutation detection, gene expression, etc.), mass spectrometry, and protein-specific methodologies. All revised chapters have been completely updated, to include not only technology innovations, but also novel diagnostic applications. As with previous editions, each of the chapters in this section includes a brief description of the technique followed by examples from the area of expertise from the selected contributor. The second part of the book attempts to integrate previously analyzed technologies into the different aspects of molecular diagnostics, such as identification of genetically modified organisms, stem cells, pharmacogenomics, modern forensic science, molecular microbiology, and genetic diagnosis. Part three focuses on various everyday issues in a diagnostic laboratory, from genetic counseling and related ethical and psychological issues, to safety and quality management. Presents a comprehensive account of all new technologies and applications used in clinical diagnostic laboratories Explores a wide range of molecular-based tests that are available to assess DNA variation and changes in gene expression Offers clear translational presentations by the top molecular pathologists, clinical chemists, and molecular geneticists in the field

Plant Pathology Concepts and Laboratory Exercises Second Edition

Plant Pathology Concepts and Laboratory Exercises  Second Edition Book
Author : Robert N. Trigiano,Mark Townsend Windham,Alan S. Windham
Publisher : CRC Press
Release : 2008
ISBN :
Language : En, Es, Fr & De

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Book Description :

Including contributions from specialists with extensive experience in the field, this second edition features new chapters on pathogenic prokaryotes, soilborne pathogens, and host-pathogen interactions. It increases coverage of a number of molecular techniques-including real-time PCR methods for pathogen detection, AFLPs, and AGDIA methods-and insect vectoring of bacterial pathogens with potential control strategies. A more detailed discussion of disease diagnosis is also provided. An accompanying CD-ROM offers a wide range of full-colour illustrations to enhance understanding of concepts. Additional references and case studies have been added to the text.

Plant Pathology Concepts and Laboratory Exercises Second Edition

Plant Pathology Concepts and Laboratory Exercises  Second Edition Book
Author : Robert N. Trigiano
Publisher : CRC Press
Release : 2007-11-30
ISBN : 1482226936
Language : En, Es, Fr & De

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Book Description :

Revised and updated with new concepts, case studies, and laboratory exercises, Plant Pathology Concepts and Laboratory Exercises, Second Edition supplies highly detailed and accurate information in a well-organized and accessible format. New additions to the second edition include five new topic and exercise chapters on soilborne pathogens, molecular tools, biocontrol, and plant-fungal interactions, information on in vitro pathology, an appendix on plant pathology careers, and how to use and care for the microscope. An accompanying cd-rom contains figures from the text as well as supplemental full-color photos and PowerPoint slides. Unique Learning Tools Retaining the informal style of the previous edition, this volume begins each topic with a concept box to highlight important ideas. Several laboratory exercises support each topic and cater to a wide range of skill sets from basic to complex. Procedure boxes for the experimental exercises give detailed outlines and comments on the experiments, step by step instruction, anticipated results, and thought provoking questions. Case studies of specific diseases and processes are presented as a bulleted list supplying essential information at a glance. Comprehensive Coverage Divided into six primary parts, this valuable reference introduces basic concepts of plant pathology with historical perspectives, fundamental ideas of disease, and disease relationships with the environment. It details various disease-causing organisms including viruses, prokaryotic organisms, plant parasitic nematodes, fungi, plant parasitic seed plants, and other biotic and abiotic diseases. Exploring various plant-pathogen interactions including treatments of molecular attack strategies, extracellular enzymes, host defenses, and disruption of plant function, the book presents the basic ideas of epidemiology, control strategies, and disease diagnosis.

Plant Pathology Concepts and Laboratory Exercises Third Edition

Plant Pathology Concepts and Laboratory Exercises  Third Edition Book
Author : Bonnie H. Ownley,Robert N. Trigiano
Publisher : CRC Press
Release : 2016-03-26
ISBN : 9781466500815
Language : En, Es, Fr & De

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Book Description :

Continuing in the tradition of its predecessors, this new edition combines an informal, easy to read style with a thorough introduction to concepts and terminology of plant pathology. After reviewing fundamental concepts, the book discusses groups of plant pathogens and molecular tools for studying them, pathogen interactions, epidemiology and disease control, and special topics in plant pathology. The book details various disease-causing organisms, including viruses, fungi, prokaryotics, nematodes, and various biotic agents. It also examines various plant-pathogen interactions, molecular attack strategies, extracellular enzymes, host defenses, and disruption of plant function.

Molecular Pathology An Issue of Clinics in Laboratory Medicine

Molecular Pathology  An Issue of Clinics in Laboratory Medicine  Book
Author : Martin H. Bluth
Publisher : Elsevier Health Sciences
Release : 2013-11-30
ISBN : 0323261051
Language : En, Es, Fr & De

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Book Description :

Molecular pathology has significantly matured over the past decade to establish itself as a discipline in its own right. Patient diagnosis, prognosis, management and care have been influenced by molecular pathology testing algorithms on a global scale. Whether it pertains to carrier status of deleterious genes, diagnosis by molecular techniques, assessment of appropriate remission post treatment, parentage or forensics testing – molecular pathology continues to increase its presence and influence in the diagnostic laboratory armamentarium. Furthermore, intellectualization and proprietization of molecular pathology with respect to the discovery of new genes and or new techniques continues to pose new challenges of test ownership, legalities, liabilities, widespread acceptance and utility. This issue of Laboratory Clinics seeks to provide selective state of the art understanding of molecular pathology with respect to its relationship to key pathology disciplines as well as the current challenges and promise for the future.

Essential Forensic Pathology

Essential Forensic Pathology Book
Author : Gilbert Corrigan
Publisher : CRC Press
Release : 2012-02-14
ISBN : 1466554150
Language : En, Es, Fr & De

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Book Description :

A myriad of different scenarios await those entering the field of forensic pathology, ranging from gunshot wounds to asphyxiation to explosives to death from addiction. Essential Forensic Pathology: Core Studies and Exercises helps prepare pathologists in training by establishing what they must know about the most common death scenes they will enco

AFIP Letter

AFIP Letter Book
Author : Armed Forces Institute of Pathology (U.S.)
Publisher :
Release : 1989
ISBN :
Language : En, Es, Fr & De

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Book Description :

Practical Plant Virology

Practical Plant Virology Book
Author : Jeanne Dijkstra,Cees de Jager
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 3642720307
Language : En, Es, Fr & De

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Book Description :

Viruses require a special approach to establish their presence in a diseased plant since they are not visible, even under a light microscope. This manual describes in detail a variety of protocols for determining the properties and identity of a virus and its behavior in infected plants. A Springer Lab Manual.

Conceptual Advances in Pathology An Issue of Clinics in Laboratory Medicine E Book

Conceptual Advances in Pathology  An Issue of Clinics in Laboratory Medicine   E Book Book
Author : Zoltan Oltvai
Publisher : Elsevier Health Sciences
Release : 2012-09-16
ISBN : 1455747866
Language : En, Es, Fr & De

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Book Description :

This issue of Clinics in Laboratory Medicine titled, "Conceptual Advances in Pathology" addresses the key factors impacting pathology and details the technology surrounding the field. The Guest Editor, Zoltan Oltvai, MD., splits the issue into three sections; Technological Advances, Process Advances, Educational and Practice Needs, and the Business of Pathology.

Practical Exercises in Parasitology

Practical Exercises in Parasitology Book
Author : British Society for Parasitology
Publisher : Cambridge University Press
Release : 2001-03-22
ISBN : 9780521791045
Language : En, Es, Fr & De

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Book Description :

An excellent practical guide to hands-on teaching of parasitology in the laboratory.

Plant Propagation Concepts and Laboratory Exercises

Plant Propagation Concepts and Laboratory Exercises Book
Author : Caula A. Beyl,Robert N. Trigiano
Publisher : CRC Press
Release : 2016-01-06
ISBN : 1466503882
Language : En, Es, Fr & De

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Book Description :

Includes a DVD Containing All Figures and Supplemental Images in PowerPoint This new edition of Plant Propagation Concepts and Laboratory Exercises presents a robust view of modern plant propagation practices such as vegetable grafting and micropropagation. Along with foundation knowledge in anatomy and plant physiology, the book takes a look into the future and how cutting edge research may impact plant propagation practices. The book emphasizes the principles of plant propagation applied in both temperate and tropical environments. In addition to presenting the fundamentals, the book features protocols and practices that students can apply in both laboratory and field experiences. The book shows readers how to choose the best methods for plant propagation including proper media and containers as well as performing techniques such as budding, cutting, layering, grafting, and cloning. It also discusses how to recognize and cope with various propagation challenges. Also included are concept chapters highlighting key information, laboratory exercises, anticipated laboratory results, stimulating questions, and a DVD containing all the figures in the book as well as some supplemental images.

Step by Step Medical Coding 2013 Edition E Book

Step by Step Medical Coding  2013 Edition   E Book Book
Author : Carol J. Buck
Publisher : Elsevier Health Sciences
Release : 2014-06-18
ISBN : 0323292003
Language : En, Es, Fr & De

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Book Description :

Take your first step toward a successful career in medical coding with comprehensive coverage from the most trusted source in the field! Step-by-Step Medical Coding, 2013 Edition is the practical, easy-to-use resource that shows you exactly how to code using all of today's coding systems. In-depth, step-by-step explanations of essential coding concepts are followed by practice exercises to reinforce your understanding. In addition to coverage of reimbursement, ICD-9-CM, CPT, HCPCS, and inpatient coding, the 2013 edition offers complete coverage of the ICD-10-CM diagnosis coding system in preparation for the eventual transition. No other text on the market so thoroughly prepares you for all coding sets in one source! Dual coding in Units 4 and 5 (where both ICD-10 and ICD-9 answers are provided for every exercise, chapter review, and workbook question) ensures you can code using the systems of both today and tomorrow. Complete coverage of the new ICD-10 code set in Unit 2 prepares you for the eventual transition from ICD-9 to ICD-10. Official Guidelines for Coding and Reporting boxes in Units 2, 3, and 5 present the official outpatient and inpatient guidelines alongside text discussions. Concrete "real-life" coding examples help you apply important coding principles and practices to actual scenarios from the field. Over 500 total illustrations of medical procedures or conditions help you understand the services being coded. Four coding question variations develop your coding ability and critical thinking skills: One answer blank for coding questions that require a one-code answer Multiple answer blanks for coding questions that require a multiple-code answer Identifiers next to the answer blank(s) to guide you through the most difficult coding scenarios Answer blanks with a preceding symbol (3 interlocking circles) indicates that the user must decide the number of codes necessary to correctly answer the question In-text exercises, Quick Checks, and Toolbox features reinforce coding rules and concepts, emphasize key information, and test your retention and understanding. From the Trenches, Coding Shots, Stop!, Caution!, Check This Out!, and CMS Rules boxes offer valuable, up-to-date tips and advice for working in today’s medical coding field. Coder’s Index makes it easy to instantly locate specific codes. Practice activities on the companion Evolve website reinforce key concepts from the text. Updated content presents the latest coding information so you can practice with the most current information available.

Plant Tissue Culture Development and Biotechnology

Plant Tissue Culture  Development  and Biotechnology Book
Author : Robert N. Trigiano,Dennis J. Gray
Publisher : CRC Press
Release : 2016-03-30
ISBN : 1439896143
Language : En, Es, Fr & De

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Book Description :

Under the vast umbrella of Plant Sciences resides a plethora of highly specialized fields. Botanists, agronomists, horticulturists, geneticists, and physiologists each employ a different approach to the study of plants and each for a different end goal. Yet all will find themselves in the laboratory engaging in what can broadly be termed biotechnol

Review Manual to Henry s Clinical Diagnosis and Management by Laboratory Methods

Review Manual to Henry s Clinical Diagnosis and Management by Laboratory Methods Book
Author : Katherine I. Schexneider
Publisher : W B Saunders Company
Release : 2005
ISBN : 9781416000532
Language : En, Es, Fr & De

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Book Description :

This comprehensive workbook companion to Henry's Clinical Diagnosis and Management by Laboratory Methods is designed to help pathology residents prepare for their board certification exams. It covers information that is likely to appear on the boards and that will also prove useful for day-to-day reference in the post-qualification years. Using a parallel organization to Dr. Henry's classic textbook, the workbook presents concise, bullet-point summaries of every important concept, as well as more than 1,320 review questions and answers, word association drills, image interpretation exercises, and a mathematical formula exam to challenge users' mastery of the material. Accompanies the most authoritative reference book in clinical and laboratory pathology, Henry's Clinical Diagnosis and Management by Laboratory Methods. Presents concise, bullet-point summaries of all essential information in 7 key areas: The Clinical Laboratory · Clinical Chemistry · Urine and Other Body Fluids · Hematology, Coagulation and Transfusion Medicine · Immunology and Immunopathology · Medical Microbiology · and Molecular Pathology. Offers more than 1,320 multiple-choice test questions and answers to evaluate readers' knowledge. Provides extensive practice in using the mathematical formulas needed in hematology, blood banking, and chemistry. Includes a comprehensive picture identification segment to mimic the Kodachrome Simulation Examination part of the board exam, with 40 multiple-choice questions and answers based on color images.