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Key Molecular Players In Stem Cell Biology

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Molecular Players in iPSC Technology

Molecular Players in iPSC Technology Book
Author : Alexander Birbrair
Publisher : Academic Press
Release : 2021-08-29
ISBN : 0323900607
Language : En, Es, Fr & De

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Book Description :

The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. Molecular Players in iPSC Technology, Volume 12 addresses the molecular players underlying induced pluripotent stem cell (iPSC) generation, maintenance, expansion, and differentiation. The discovery of iPSCs revolutionized biomedical research. iPSC technology involves multiple molecular mechanisms. This volume covers exosomal microRNAs, auxiliary pluripotency-associated genes, inducible caspase-9 suicide gene, cell cycle proteins, ion channels, Notch signaling, kinase signaling, SOCS3/JAK2/STAT3 pathway, NANOG, Krüppel-like factors, H1FOO, and much more in iPSCs. The volume is written for researchers and scientists in stem cell therapy, cellular and molecular biology, and regenerative medicine and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of iPSC technology, regenerative medicine, and therapeutics Covers the different key molecular players involved in iPSC formation, maintenance, expansion, and differentiation Is contributed by world-renowned experts in the field

Concepts and Applications of Stem Cell Biology

Concepts and Applications of Stem Cell Biology Book
Author : Gabriela Rodrigues,Bernard A. J. Roelen
Publisher : Springer Nature
Release : 2020-06-30
ISBN : 3030439399
Language : En, Es, Fr & De

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Book Description :

This textbook will support graduate students with learning materials rich in the basic concepts of stem cell biology, in its most widespread and updated perspective. The chapters are conceived in a way for students to understand the meaning of pluripotency, the definition of embryonic stem cells and the formation of multicellular structures such as organoids together with the underlying principles of their epigenetic. This textbook also discusses adult stem cells and the potential use of these cells, in particular neural, mesenchymal, and several types of muscular cells, in biomedical research and clinical applications. This textbook represents a vital complement to the text on Essential Current Concepts of Stem Cell Biology, also published in the Learning Materials in Biosciences textbook series.

Fundamentals of the Stem Cell Debate

Fundamentals of the Stem Cell Debate Book
Author : Kristen Renwick Monroe,Ronald Miller,Jerome Tobis
Publisher : Univ of California Press
Release : 2008
ISBN : 0520252128
Language : En, Es, Fr & De

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Book Description :

"What the editors have managed to accomplish with Fundamentals of the Stem Cell Debate is very significant. The book is well-informed, sophisticated, and attends to the moral and scientific complexities of stem cell research, rather than sweeping them under the rug. This book encompasses the complexities without sacrificing the other main virtue of the collection: to definitively illuminate the debate for all."—Jason Scott Robert, author of Embryology, Epigenesis, & Evolution: Taking Development Seriously

Stem Cell Biology and Tissue Engineering in Dental Sciences

Stem Cell Biology and Tissue Engineering in Dental Sciences Book
Author : Ajaykumar Vishwakarma,Paul Sharpe,Songtao Shi,Murugan Ramalingam
Publisher : Academic Press
Release : 2014-11-05
ISBN : 0123977789
Language : En, Es, Fr & De

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Book Description :

Stem Cell Biology and Tissue Engineering in Dental Sciences bridges the gap left by many tissue engineering and stem cell biology titles to highlight the significance of translational research in this field in the medical sciences. It compiles basic developmental biology with keen focus on cell and matrix biology, stem cells with relevance to tissue engineering biomaterials including nanotechnology and current applications in various disciplines of dental sciences; viz., periodontology, endodontics, oral & craniofacial surgery, dental implantology, orthodontics & dentofacial orthopedics, organ engineering and transplant medicine. In addition, it covers research ethics, laws and industrial pitfalls that are of particular importance for the future production of tissue constructs. Tissue Engineering is an interdisciplinary field of biomedical research, which combines life, engineering and materials sciences, to progress the maintenance, repair and replacement of diseased and damaged tissues. This ever-emerging area of research applies an understanding of normal tissue physiology to develop novel biomaterial, acellular and cell-based technologies for clinical and non-clinical applications. As evident in numerous medical disciplines, tissue engineering strategies are now being increasingly developed and evaluated as potential routine therapies for oral and craniofacial tissue repair and regeneration. Diligently covers all the aspects related to stem cell biology and tissue engineering in dental sciences: basic science, research, clinical application and commercialization Provides detailed descriptions of new, modern technologies, fabrication techniques employed in the fields of stem cells, biomaterials and tissue engineering research including details of latest advances in nanotechnology Includes a description of stem cell biology with details focused on oral and craniofacial stem cells and their potential research application throughout medicine Print book is available and black and white, and the ebook is in full color

Stem Cell Regulators

Stem Cell Regulators Book
Author : Gerald Litwack
Publisher : Academic Press
Release : 2011
ISBN : 0123860156
Language : En, Es, Fr & De

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Book Description :

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines. This volume focuses on stem cell regulators. Longest running series published by Academic Press Contributions by leading international authorities

Stem Cells

Stem Cells Book
Author : Mary Clarke,Jonathan Frampton
Publisher : Garland Science
Release : 2020-07-27
ISBN : 1000062651
Language : En, Es, Fr & De

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Book Description :

Stem cell science, encompassing basic biology to practical application, is both vast and diverse. A full appreciation of it requires an understanding of cell and molecular biology, tissue structure and physiology, the practicalities of tissue engineering and bioprocessing, and the pathways to clinical implementation—including the ethical and regulatory imperatives that our society requires us to address. Expectation and debate have been driven by the allure of regenerative medicine using stem cells as a source of replacements for damaged or aged tissues. The potential of stem cell application goes far beyond this. Highly innovative uses of stem cells are emerging as possible therapies for cancers, treating acute damage in conditions such as stroke and myocardial infarction, and resolving a whole range of diseases. Stem Cells: Biology and Application presents the basic concepts underlying the fast-moving science of stem cell biology. This textbook is written for an advanced stem cell biology course. The target audience includes senior undergraduates, first year graduate students, and practitioners in molecular biology, biology, and biomedical engineering. Stem Cells provides a comprehensive understanding of these unique cells, highlighting key areas of research, associated controversies, case studies, technologies, and pioneers in the field.

Prominin 1 CD133 New Insights on Stem Cancer Stem Cell Biology

Prominin 1  CD133   New Insights on Stem   Cancer Stem Cell Biology Book
Author : Denis Corbeil
Publisher : Springer Science & Business Media
Release : 2012-11-19
ISBN : 1461458943
Language : En, Es, Fr & De

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Book Description :

​​​​​​​Prominin-1 or otherwise known as CD133 is a glycoprotein that is present in humans and mice. Since the first description of prominin in 1997, in mouse neuroepithelial cells and in human hematopoietic stem cells as AC133 antigen, this molecule has aroused a large interest especially, as a stem cell marker, that gave rise to an ever growing body of publications and more recently its expression in cancer stem cells. Controversies as to its role as a cancer stem and its detection in different models, as well as its use as a prognostic marker have emerged. Yet, beyond its use as a stem cell and cancer stem cell marker, prominin-1/CD133 displays unique biological features and appears of importance in other processes like for example in retinal biogenesis. Indeed, this five-transmembrane plasma membrane glycoprotein, which marks membrane protrusions is associated with several essential processes like cell polarity, asymmetric cell division and membrane remodeling. We propose to review current knowledge about this intriguing molecule and present pertinent information to determine the biological role of prominins and assess their importance in medicine and cancer research. The primary audience for this book is geared towards scientists and researchers with interest in cancer stem cells, stem cells, cell biology, neurobiology, and regenerative medicine.

Brain Disease Mechanisms Editor s Picks 2021

Brain Disease Mechanisms   Editor   s Picks 2021 Book
Author : Detlev Boison
Publisher : Frontiers Media SA
Release : 2021-07-21
ISBN : 2889710637
Language : En, Es, Fr & De

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Book Description :

Download Brain Disease Mechanisms Editor s Picks 2021 book written by Detlev Boison, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Biobanking and Cryopreservation of Stem Cells

Biobanking and Cryopreservation of Stem Cells Book
Author : Feridoun Karimi-Busheri,Michael Weinfeld
Publisher : Springer
Release : 2016-11-10
ISBN : 3319454579
Language : En, Es, Fr & De

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Book Description :

Biobanking is considered to be one of the ten ideas changing the world with an estimated value of $45 billion by 2025. Despite the challenges, as the climate for innovation in the biobanking industry continues to flourish around the world, it is certain that amazing discoveries will emerge from this large-scale method of preserving and accessing human samples; biobanking is no longer just a place for collecting and storing samples. This book will cover a wide variety of subjects from across the future biobanking spectrum including scientific strategies, personalized medicine, regenerative medicine and stem cell challenges, disease surveillance, population genetics and innovative methods of biobanking.

Extracellular Matrix Dynamics in Biology Bioengineering and Pathology

Extracellular Matrix Dynamics in Biology  Bioengineering  and Pathology Book
Author : Rajprasad Loganathan,Charles D. Little,Brenda J. Rongish
Publisher : Frontiers Media SA
Release : 2020-11-19
ISBN : 2889661199
Language : En, Es, Fr & De

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Book Description :

Download Extracellular Matrix Dynamics in Biology Bioengineering and Pathology book written by Rajprasad Loganathan,Charles D. Little,Brenda J. Rongish, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Adult Stem Cells

Adult Stem Cells Book
Author : Kursad Turksen
Publisher : Springer Science & Business Media
Release : 2004-01-27
ISBN : 1592597327
Language : En, Es, Fr & De

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Book Description :

Studies on stem cells have been attracting intense scientific and p- lic attention, not only because of controversies surrounding the use of embryonic stem cells but also because of very provocative data that have been emerging on adult stem cells. Much of the public attention and debate has been focused on the possibility that adult stem cells may be used as a substitute for human embryonic stem cells or as a justification for stopping work on them. This has somewhat dim- ished attention on very heated scientific debates that take us to the very heart of how the concept of stem cells is perceived. To this author, the latter debates have not been unlike certain philosophical debates of the last century. Since the seminal studies of Till and McCulloch in the 1960s, the popular paradigm on adult stem cells has been that lineage-restricted stem cells are derived from pluripotent stem cells very early during development. To many, and consistent with much data, the restriction to particular lineages was considered absolute. In other words, there was a sense of determinism in the stem quality of particular stem cells: once they were allocated, they were programmed to specific roles in a given tissue. Furthermore, some adult tissues were considered devoid of detectable stem cell presence or activity.

Key Players in Systemic Sclerosis The Immune System and Beyond

Key Players in Systemic Sclerosis  The Immune System and Beyond Book
Author : Philippe Guilpain,Danièle Noël,Jérôme Avouac
Publisher : Frontiers Media SA
Release : 2021-11-29
ISBN : 2889717445
Language : En, Es, Fr & De

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Book Description :

Download Key Players in Systemic Sclerosis The Immune System and Beyond book written by Philippe Guilpain,Danièle Noël,Jérôme Avouac, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Stem Cells Advances in Research and Application 2012 Edition

Stem Cells   Advances in Research and Application  2012 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2012-12-26
ISBN : 1464991251
Language : En, Es, Fr & De

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Book Description :

Stem Cells—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Stem Cells. The editors have built Stem Cells—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Stem Cells in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Stem Cells—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Essentials of Stem Cell Biology

Essentials of Stem Cell Biology Book
Author : Robert Lanza,John Gearhart,Brigid Hogan,Douglas Melton,Roger Pedersen,E. Donnall Thomas,James A. Thomson,Ian Sir Wilmut
Publisher : Academic Press
Release : 2009-06-05
ISBN : 9780080884974
Language : En, Es, Fr & De

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Book Description :

First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing the latest advances in stem cells. Representing the combined effort of seven editors and more than 200 scholars and scientists whose pioneering work has defined our understanding of stem cells, this book combines the prerequisites for a general understanding of adult and embryonic stem cells with a presentation by the world's experts of the latest research information about specific organ systems. From basic biology/mechanisms, early development, ectoderm, mesoderm, endoderm, methods to application of stem cells to specific human diseases, regulation and ethics, and patient perspectives, no topic in the field of stem cells is left uncovered. Selected for inclusion in Doody's Core Titles 2013, an essential collection development tool for health sciences libraries Contributions by Nobel Laureates and leading international investigators Includes two entirely new chapters devoted exclusively to induced pluripotent stem (iPS) cells written by the scientists who made the breakthrough Edited by a world-renowned author and researcher to present a complete story of stem cells in research, in application, and as the subject of political debate Presented in full color with glossary, highlighted terms, and bibliographic entries replacing references

The Cell Biology of Stem Cells

The Cell Biology of Stem Cells Book
Author : Eran Meshorer,Kathrin Plath
Publisher : Springer Science & Business Media
Release : 2011-01-11
ISBN : 1441970371
Language : En, Es, Fr & De

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Book Description :

Stem cells have been gaining a lot of attention in recent years. Their unique potential to self-renew and differentiate has turned them into an attractive model for the study of basic biological questions such as cell division, replication, transcription, cell fate decisions, and more. With embryonic stem (ES) cells that can generate each cell type in the mammalian body and adult stem cells that are able to give rise to the cells within a given lineage, basic questions at different developmental stages can be addressed. Importantly, both adult and embryonic stem cells provide an excellent tool for cell therapy, making stem cell research ever more pertinent to regenerative medicine. As the title The Cell Biology of Stem Cells suggests, our book deals with multiple aspects of stem cell biology, ranging from their basic molecular characteristics to the in vivo stem cell trafficking of adult stem cells and the adult stem-cell niche, and ends with a visit to regeneration and cell fate reprogramming. In the first chapter, “Early embryonic cell fate decisions in the mouse”, Amy Ralson and Yojiro Yamanaka describe the mechanisms that support early developmental decisions in the mouse pre-implantation embryo and the current understanding of the source of the most immature stem cell types, which includes ES cells, trophoblast stem (TS) cells and extraembryonic endoderm stem (XEN) cells.

Handbook of Systems Biology

Handbook of Systems Biology Book
Author : Marian Walhout,Marc Vidal,Job Dekker
Publisher : Academic Press
Release : 2012-12-31
ISBN : 012385945X
Language : En, Es, Fr & De

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Book Description :

This book provides an entry point into Systems Biology for researchers in genetics, molecular biology, cell biology, microbiology and biomedical science to understand the key concepts to expanding their work. Chapters organized around broader themes of Organelles and Organisms, Systems Properties of Biological Processes, Cellular Networks, and Systems Biology and Disease discuss the development of concepts, the current applications, and the future prospects. Emphasis is placed on concepts and insights into the multi-disciplinary nature of the field as well as the importance of systems biology in human biological research. Technology, being an extremely important aspect of scientific progress overall, and in the creation of new fields in particular, is discussed in 'boxes' within each chapter to relate to appropriate topics. 2013 Honorable Mention for Single Volume Reference in Science from the Association of American Publishers' PROSE Awards Emphasizes the interdisciplinary nature of systems biology with contributions from leaders in a variety of disciplines Includes the latest research developments in human and animal models to assist with translational research Presents biological and computational aspects of the science side-by-side to facilitate collaboration between computational and biological researchers

Bone Marrow Cells Advances in Research and Application 2012 Edition

Bone Marrow Cells   Advances in Research and Application  2012 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2012-12-26
ISBN : 1464992525
Language : En, Es, Fr & De

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Book Description :

Bone Marrow Cells—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Bone Marrow Cells. The editors have built Bone Marrow Cells—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Bone Marrow Cells in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Bone Marrow Cells—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Goodman s Medical Cell Biology

Goodman s Medical Cell Biology Book
Author : Steven R. Goodman
Publisher : Academic Press
Release : 2020-06-11
ISBN : 0128179287
Language : En, Es, Fr & De

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Book Description :

Goodman’s Medical Cell Biology, Fourth Edition, has been student tested and approved for decades. This updated edition of this essential textbook provides a concise focus on eukaryotic cell biology (with a discussion of the microbiome) as it relates to human and animal disease. This is accomplished by explaining general cell biology principles in the context of organ systems and disease. This new edition is richly illustrated in full color with both descriptive schematic diagrams and laboratory findings obtained in clinical studies. This is a classic reference for moving forward into advanced study. Includes five new chapters: Mitochondria and Disease, The Cell Biology of the Immune System, Stem Cells and Regenerative Medicine, Omics, Informatics, and Personalized Medicine, and The Microbiome and Disease Contains over 150 new illustrations, along with revised and updated illustrations Maintains the same vision as the prior editions, teaching cell biology in a medically relevant manner in a concise, focused textbook

Advanced Techniques in Bone Regeneration

Advanced Techniques in Bone Regeneration Book
Author : Alessandro Rozim Zorzi,João Batista de Miranda
Publisher : BoD – Books on Demand
Release : 2016-08-31
ISBN : 9535125389
Language : En, Es, Fr & De

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Book Description :

Advanced Techniques in Bone Regeneration is a book that brings together over 15 chapters, written by leading practitioners and researchers, of the latest advances in the area, including surgical techniques, new discoveries, and promising methods involving biomaterials and tissue engineering. This book is intended for all who work in the treatment of disorders involving problems with the regeneration of bone tissue, are doctors or dentists, as well as are researchers and teachers involved in this exciting field of scientific knowledge.

Pluripotent Stem Cells

Pluripotent Stem Cells Book
Author : Deepa Bhartiya,Nibedita Lenka
Publisher : BoD – Books on Demand
Release : 2013-08-28
ISBN : 9535111922
Language : En, Es, Fr & De

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Book Description :

Stem cells have generated a lot of excitement among the researchers, clinicians and the public alike. Various types of stem cells are being evaluated for their regenerative potential. Marginal benefit resulting by transplanting autologus stem cells (deemed to be absolutely safe) in various clinical conditions has been proposed to be a growth factor effect rather than true regeneration. In contrast, various pre-clinical studies have been undertaken, using differentiated cells from embryonic stem cells or induced pluripotent stem cells have shown promise, functional improvement and no signs of teratoma formation. The scientists are not in a rush to reach the clinic but a handful of clinical studies have shown promise. This book is a collection of studies/reviews, beginning with an introduction to the pluripotent stem cells and covering various aspects like derivation, differentiation, ethics, etc., and hence would provide insight into the recent standing on the pluripotent stem cells biology. The chapters have been categorized into three sections, covering subjects ranging from the generation of pluripotent stem cells and various means of their derivation from embryonic as well as adult tissues, the mechanistic understanding of pluripotency and narrating the potential therapeutic implications of these in vitro generated cells in various diseases, in addition to the associated pros and cons in the same.