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Key Heterocycle Cores For Designing Multitargeting Molecules

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Key Heterocycle Cores for Designing Multitargeting Molecules

Key Heterocycle Cores for Designing Multitargeting Molecules Book
Author : Om Silakari
Publisher : Elsevier
Release : 2018-06-11
ISBN : 0081021054
Language : En, Es, Fr & De

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Book Description :

Key Heterocycle Cores for Designing Multitargeting Molecules provides a helpful overview of current developments in the field. Following a detailed introduction to the manipulation of heterocycle cores for the development of dual or multitargeting molecules, the book goes on to describe specific examples of such developments, focusing on compounds such as Benzimidazole, Acridine, Flavones, Thiazolidinedione and Oxazoline. Drawing on the latest developments in the field, this volume provides a valuable guide to current approaches in the design and development of molecules capable of acting on multiple targets. Adapting the heterocyclic core of a single-target molecule can facilitate its development into an agent capable of acting on multiple targets. Such multi-targeting drugs have the potential to become essential components in the design of novel, holistic treatment plans for complex diseases, making the design of such active agents an increasingly important area of research. Emphasizes the chemical development of heterocyclic nuclei, from single to multitargeting molecules Provides chapter-by-chapter coverage of the key heterocyclic compounds used in synthesizing multitargeting agents Outlines current trends and future developments in multitarget molecule design for the treatment of various diseases

Advances in Heterocyclic Chemistry

Advances in Heterocyclic Chemistry Book
Author : Eric Scriven,Christopher A. Ramsden
Publisher : Academic Press
Release : 2020-05
ISBN : 0128211687
Language : En, Es, Fr & De

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Book Description :

Advances in Heterocyclic Chemistry is the definitive series in the field - one of great importance to organic chemists, polymer chemists, and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature also is being used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive review combines descriptive synthetic chemistry and mechanistic insight to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds.