Skip to main content

Ipscs As Cell Therapy For Disease Treatment

In Order to Read Online or Download Ipscs As Cell Therapy For Disease Treatment Full eBooks in PDF, EPUB, Tuebl and Mobi you need to create a Free account. Get any books you like and read everywhere you want. Fast Download Speed ~ Commercial & Ad Free. We cannot guarantee that every book is in the library!

Methods in iPSC Technology

Methods in iPSC Technology Book
Author : Alexander Birbrair
Publisher : Academic Press
Release : 2021-06-15
ISBN : 9780128238820
Language : En, Es, Fr & De

GET BOOK

Book Description :

The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs as Cell Therapy for Disease Treatment, Volume 8 addresses how important induced pluripotent stems cells are and how can they can help treat certain diseases. Somatic cells can be reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This volume will address the advances in research of how induced pluripotent stem cells are being used for treatment of different disorders, such as liver disease, type-1 diabetes, Parkinson's disease, macular degeneration of the retina and much more. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics Covers spinal cord injuries, type-1 diabetes, liver disease, Parkinson's disease, graft vs. host disease, and much more Contributed by world-renown experts in the field

Stem Cell Processing

Stem Cell Processing Book
Author : Phuc Van Pham
Publisher : Springer
Release : 2016-10-18
ISBN : 3319400738
Language : En, Es, Fr & De

GET BOOK

Book Description :

This invaluable resource delineates procedures for development and use of stem cells in the laboratory and explores the potential for clinical applications. The text discusses mesenchymal stem cell isolation, isolation of adipose derived stem cells, new trends of induced pluripotent stem cells in disease treatment, cord blood banking, future directions of the discussed therapies and much more. The chapters are contributed by preeminent scientists in the field and present a comprehensive picture of stem cell processes, from development in the laboratory to effects and side-effects of clinical application. Stem Cell Processing and the other books in the Stem Cells in Clinical Applications series, edited by Dr. Phuc Van Pham, is essential reading for scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering.

Induced Pluripotent Stem Cells in Brain Diseases

Induced Pluripotent Stem Cells in Brain Diseases Book
Author : Vivi M. Heine,Stephanie Dooves,Dwayne Holmes,Judith Wagner
Publisher : Springer Science & Business Media
Release : 2011-11-23
ISBN : 9789400728165
Language : En, Es, Fr & De

GET BOOK

Book Description :

Brain diseases can have a large impact on patients and society, and treatment is often not available. A new approach in which somatic cells are reprogrammed into induced pluripotent cells (iPS cells) is a significant breakthrough for regenerative medicine. This promises patient-specific tissue for replacement therapies, as well as disease-specific cells for developmental modeling and drug treatment screening. However, this method faces issues of low reprogramming efficiency, and poorly defined criteria for determining the conversion of one cell type to another. Cells contain epigenetic “memories” of what they were that can affect reprogramming. This book discusses the various methods to reprogram cells, the control and determination of cell identity, the epigenetic models that have emerged and the application of iPS cell therapy for brain diseases, in particular Parkinson’s disease and Vanishing White Matter (VWM).​

Stem Cells and Cell Therapy

Stem Cells and Cell Therapy Book
Author : Mohamed Al-Rubeai,Mariam Naciri
Publisher : Springer Science & Business Media
Release : 2013-10-01
ISBN : 9400771967
Language : En, Es, Fr & De

GET BOOK

Book Description :

With the discovery of stem cells capable of multiplying indefinitely in culture and differentiating into many other cell types in appropriate conditions, new hopes were born in repair and replacement of damaged cells and tissues. The features of stem cells may provide treatment for some incurable diseases with some therapies are already in clinics, particularly those from adult stem cells. Some treatments will require large number of cells and may also require multiple doses, generating a growing demand for generating and processing large numbers of cells to meet the need of clinical applications. With this in mind, our aim is to provide a book on the subject of stem cells and cell therapy for researchers and students of cell biotechnology, bioengineering and bioproduction. This book is exceptional as it teaches researchers stem cells and cell therapy in that it covers the concepts and backgrounds necessary so that readers get a good understanding of the production of stem cells. The book covers three topics: The basics of stem cells and cell therapy, the use of stem cells for the treatment of human diseases, and stem cell processing. It includes chapters on neural and vascular stem vascular stem cell therapy, expansion engineering of embryonic stem cells, stem cell based production of blood cells and separation technologies for stem cells and cell therapy products. It is an informed and informative presentation of what modern research, science and engineering have learned about stem cells and their production and therapies. Addressing both the medical and production issues, this book is an invaluable contribution to having an academic and industrial understanding with respect to R&D and manufacturing of clinical grade stem cells.

Stem Cells

Stem Cells Book
Author : Mariusz Z. Ratajczak
Publisher : Springer Nature
Release :
ISBN : 3030312062
Language : En, Es, Fr & De

GET BOOK

Book Description :

iPS Cells for Modelling and Treatment of Human Diseases

iPS Cells for Modelling and Treatment of Human Diseases Book
Author : Michael J. Edel
Publisher : MDPI
Release : 2018-10-02
ISBN : 3038421227
Language : En, Es, Fr & De

GET BOOK

Book Description :

This book is a printed edition of the Special Issue "iPS Cells for Modelling and Treatment of Human Diseases" that was published in JCM

Emerging Trends in Cell and Gene Therapy

Emerging Trends in Cell and Gene Therapy Book
Author : Michael K. Danquah,Ram I. Mahato
Publisher : Springer Science & Business Media
Release : 2013-06-14
ISBN : 162703417X
Language : En, Es, Fr & De

GET BOOK

Book Description :

Examples from various organs and diseases illustrate the potential benefit obtained when both therapeutic approaches are combined with delivery strategies. Representing the combined effort of several leading international research and clinical experts, this book, Emerging Trends in Cell and Gene Therapy, provides a complete account on and brings into sharp focus current trends and state-of-the-art in important areas at the interface of cell- and gene-based therapies. This book addresses the current fragmented understanding regarding these two research areas and fills the vast unmet educational need and interest of both students and researchers in academia and industry. Main features of the book: · Biological aspects of stem cell sources, differentiation and engineering. · Application of microfluidics to study stem cell dynamics · Potential clinical application of stem cells and gene therapy to specific human disease. · Utilization of biomaterials and stem cells in regenerative medicine with particular emphasis on spinal cord repair, ligament and bone tissue engineering. · Biomimetic multiscale topography for cell alignment.

Advances in Stem Cell Therapy

Advances in Stem Cell Therapy Book
Author : Nagwa El-Badri
Publisher : Humana Press
Release : 2016-11-18
ISBN : 3319291491
Language : En, Es, Fr & De

GET BOOK

Book Description :

The book reviews the main approaches for generation of differentiated cells from various types of stem cells, including embryonic, placental and cord blood stem cells through marrow, adipose tissue and dental pulp. The book starts with an overview of experimental protocols applied to generate insulin secreting cells, neural cells, heart cells, and other tissue specific cells ex vivo and in experimental animals. This is followed by exhaustive review of clinical trials in these pathologies. It continues with a comparison of the merits of successful transplantation in humans versus animal experimentation, and highlights the most promising clinical applications in the field. Special chapters are devoted to the topic of tissue engineering and modern synthetic and biological scaffolds. It is essential reading for scientists and researchers in tissue engineering and stem cell research as well as clinicians who are involved in developing or testing stem cell therapies.

Cell Press Reviews Stem Cells to Model and Treat Disease

Cell Press Reviews  Stem Cells to Model and Treat Disease Book
Author : Cell Press
Publisher : Elsevier
Release : 2013-12-03
ISBN : 0127999167
Language : En, Es, Fr & De

GET BOOK

Book Description :

Cell Press Reviews: Stem Cells to Model and Treat Disease informs, inspires, and connects stem cell researchers and clinicians at all stages in their careers with timely, comprehensive reviews written by leaders in the field and curated by Cell Press editors. The publication offers a broad view of some of the most compelling topics in stem cell research including: Safety and efficacy of stem cell treatments Stem-cell-based organ regeneration Integrating stem cells into personalized drug discovery Using pluripotent stem cells for treating neurological disease Engineering hematopoietic stem cells for innovative therapies Contributions come from leading voices in the field, including: - Shinya Yamanaka, Recipient of the 2012 Nobel Prize for Physiology or Medicine, Recipient of the 2012 Millennium Technology Prize, Professor and Director of the Center for iPS Cell Research and Application at Kyoto University, Senior Investigator at the Gladstone Institute of Cardiovascular Disease, L.K. Whittier Foundation Investigator in Stem Cell Biology and Professor at the University of California, San Francisco - George Q. Daley, Samuel E. Lux IV Professor of Hematology/Oncology at Harvard Medical School and Director for the Stem Cell Transplantation Program at Boston Children’s Hospital - Irving Weissman, Member of National Academy of Sciences, Virgina & D.K Ludwig Professor for Clinical Investigation in Cancer Research, and Director for Institute of Stem Cell Biology and Regenerative Medicine at Stanford University of Medicine Cell Press Reviews: Stem Cells to Model and Treat Disease is part of the Cell Press Reviews series, which features reviews published in Cell Press primary research and Trends reviews journals. Provides timely overviews on a wide range of stem cell applications Offers insight from experts on the key opportunities and challenges facing the field Features reviews on genetic, cellular, and molecular aspects of stem-cell-based applications Includes articles originally published in Cell, Cell Stem Cell, Neuron, Trends in Molecular Medicine, and Trends in Biotechnology

Stem Cell Therapy for Parkinson s Disease

Stem Cell Therapy for Parkinson s Disease Book
Author : Fabin Han
Publisher :
Release : 2016
ISBN :
Language : En, Es, Fr & De

GET BOOK

Book Description :

Parkinson's disease (PD) is the second most common neurodegenerative disorder of aging after Alzheimer's disease (AD). Pathologically, it is characterized by a degeneration of dopamine (DA) neurons in substantia nigra of middle brain, which causes the motor symptoms and nonmotor symptoms of PD. The dopamine replacement therapy using levodopa and surgical treatment of deep brain stimulation (DBS) can only improve the symptoms of PD, but cannot stop the disease progression. Because of the selective loss of DA neurons, cell transplantation provides an exciting potential for the treatment of Parkinson's disease. The available cell sources include mesenchymal stem cells (MSCs) from bone marrow, neural stem cells (NSCs) from fetal brain tissues, embryonic stem cells (ESCs) from blastocysts, and induced pluripotent stem cells (iPSCs) reprogrammed from somatic cells transfected with stem cell transcription factors of OCT4, SOX2, KLF4, and c-MYC. Here, we first review the research advance conducted in animal models and patients of PD with these cells, then moving forward to recent development of iPSCs as a future source for the treatment of PD, and highlight the current challenges to make good manufacturing practice (GMP) standard cells suitable for large-scale production to move the cell-based therapy from dish to clinic as soon as possible.

Stem Cell based Therapy for Neurodegenerative Diseases

Stem Cell based Therapy for Neurodegenerative Diseases Book
Author : Fabin Han,Pengzhe (Paul) Lu
Publisher : Springer Nature
Release : 2020-10-26
ISBN : 9811543704
Language : En, Es, Fr & De

GET BOOK

Book Description :

This book reviews the state-of-the-art in stem-cell-based therapies for neurodegenerative diseases, and highlights advances in both animal models and clinical trials. It comprehensively discusses most neurodegenerative diseases, including such as Parkinson's, Alzheimer's and Huntington’s diseases, amyotrophic sclerosis, multiple sclerosis, muscular dystrophy and retinal degeneration, in which stem cells could potentially be used for therapy in the future. It also addresses the challenges and problems relating to the translation of stem-cell-based therapies into treatments. As such, the book will appeal to research scientists, physicians, graduate students, and medical professionals in the field of stem cells, neuroscience, neurology, neurorestoratology and major neurological disorders.

Gene and Cell Therapy

Gene and Cell Therapy Book
Author : Nancy Smyth Templeton
Publisher : CRC Press
Release : 2015-01-20
ISBN : 1466572000
Language : En, Es, Fr & De

GET BOOK

Book Description :

The Most Comprehensive, State-of-the-Art Book on Using Gene and Cell Therapy in Clinical MedicineGene and Cell Therapy: Therapeutic Mechanisms and Strategies, Fourth Edition presents extensive background and basic information, state-of-the-art technologies, important achievements, and lingering challenges in the fields of gene and cell therapies. T

Cell Biology and Translational Medicine Volume 7

Cell Biology and Translational Medicine  Volume 7 Book
Author : Kursad Turksen
Publisher : Springer Nature
Release : 2020-02-03
ISBN : 3030378454
Language : En, Es, Fr & De

GET BOOK

Book Description :

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the seventh volume of a continuing series.

Frontiers in Stem Cell and Regenerative Medicine Research Volume 9

Frontiers in Stem Cell and Regenerative Medicine Research  Volume 9 Book
Author : Atta-ur-Rahman ,Shazia Anjum
Publisher : Bentham Science Publishers
Release : 2020-05-05
ISBN : 1681087634
Language : En, Es, Fr & De

GET BOOK

Book Description :

Stem cell and regenerative medicine research is an important area of clinical research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer’s disease and retinal disorders, among others, may well be addressed employing stem cell therapies and tissue regeneration techniques. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine. This volume includes current literature on a variety of topics: -the utility of exogenous and endogenous neural stem cells in spinal cord injury -somatic cells for human induced pluripotent stem cells (iPSCs) -reactive oxygen species (ROS) mediated cellular signaling for stem cell differentiation -the therapeutic potential of microRNAs in cardiac diseases -stem cell therapy for the treatment of malaria

Stem Cells Basics and Clinical Translation

Stem Cells  Basics and Clinical Translation Book
Author : Robert Chunhua Zhao
Publisher : Springer
Release : 2015-09-14
ISBN : 9401772738
Language : En, Es, Fr & De

GET BOOK

Book Description :

This book provides a comprehensive review of the properties of various stem cell types, the mechanisms of their behaviors and their potential clinical application. Stem cells have a great capacity of self-renewal and differentiation. They represent new paradigms for disease treatment in the field of regenerative medicine since the day they were discovered. As stem cell research is complicated and making progress rapidly, it is important to have expertise in this field to share their views and perspectives. This book provides a wonderful platform for those who are interested in stem cells to learn from and communicate with experts. Particularly, it highlights the roles of stem cell based therapy for a variety of diseases. Furthermore, this book gives a detailed introduction to the great works related to stem cells in China. The readers could gain a profound knowledge of the state-of-art research done by scientists in the field of stem cells. Overall, this book will be a valuable reference resource for both experienced investigators pursuing stem cell research as well as those are just entering into this field. Dr. Robert Chunhua Zhao, a Cheung Kong Professor of Stem Cell Biology, is Professor of Cell Biology at the Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College (PUMC), Beijing, China. He is Director of the Center for Tissue Engineering, PUMC and Chief Scientist of the National Basic Research Program of China (“973 Program”). He also serves as Regional Editor of Stem Cells and Development.

Regenerative Medicine and Cell Therapy

Regenerative Medicine and Cell Therapy Book
Author : Hossein Baharvand,Nasser Aghdami
Publisher : Springer Science & Business Media
Release : 2012-08-09
ISBN : 1627030980
Language : En, Es, Fr & De

GET BOOK

Book Description :

Therapeutic applications within regenerative biomedicine has gained tremendous interest from a growing, multidisciplinary community of investigators in recent years, driven by the hope of finding cures for several diseases. Regenerative Medicine and Cell Therapy discusses cutting-edge science in the field of regenerative biomedicine and its therapeutic applications to various medical disorders. The chapters are written by renowned scientists in the specific fields. This will be a useful book for basic and clinical scientists, especially young investigators and stem cell biology students who are newly entering the world of stem cells research. The editors’ goal is that the new knowledge and research outlined in this book will help contribute to new therapies for a wide variety of diseases that presently afflict humanity.

Stem Cells

Stem Cells Book
Author : Robert A. Meyers
Publisher : John Wiley & Sons
Release : 2013-06-03
ISBN : 3527668527
Language : En, Es, Fr & De

GET BOOK

Book Description :

This third in the Current Topics in Molecular Cell Biology and Molecular Medicine Series contains a careful selection of new and updated, high-quality articles from the well-known Meyer's Encyclopedia, describing new perspectives in stem cell research. The 26 chapters are divided into four sections: Basic Biology, Stem Cells and Disease, Stem Cell Therapy Approaches, and Laboratory Methods, with the authors chosen from among the leaders in their respective fields. This volume represents an essential guide for students and researchers seeking an overview of the field.

Perinatal Stem Cells

Perinatal Stem Cells Book
Author : Zhong Chao Han,Tsuneo A. Takahashi,Zhibo Han,Zongjin Li
Publisher : Springer
Release : 2019-04-06
ISBN : 9811327033
Language : En, Es, Fr & De

GET BOOK

Book Description :

This book provides a comprehensive introduction to various types of perinatal stem cells. Given their unique regenerative abilities, stem cells offer a promising avenue in the treatment of degenerative diseases or injury. Currently, the limitations of postnatal cell sources and expanding efficiency may limit autologous stem cell therapies. Although embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) can be cultured indefinitely ex vivo, and can differentiate into three germ layers, ethical issues, the teratoma formation of ESCs and oncogenic risk of iPSCs are major obstacles to their clinical application. More recently, perinatal stem cells have been isolated from the umbilical cord, Wharton’s Jelly, placenta, amniotic membrane and amniotic fluid, which are normally discarded as medical waste. This book, after describing perinatal stem cells in detail, introduces readers to the various types of perinatal stem cells, addressing their characterization, banking, quality control and stability. Importantly, it also reviews the clinical applications of perinatal stem cells to therapy of diseases. Accordingly, it offers a valuable resource for clinicians, researchers and graduate students alike.

Cell Sources for iPSCss

Cell Sources for iPSCss Book
Author : Alexander Birbrair
Publisher : Academic Press
Release : 2021-06-15
ISBN : 9780128238080
Language : En, Es, Fr & De

GET BOOK

Book Description :

The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs for Modeling Infectious Diseases, Volume 7 addresses how important induced pluripotent stems cells are and how can they can help treat certain infectious diseases. Somatic cells can be reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This volume will address the advances in research of how induced pluripotent stem cells are being used for treatment of different infectious diseases, such as corona virus, coxsackievirus, salmonella infection, influenza virus and much more. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics Covers salmonella infection, hepatotropic pathogen infection, corona virus, influenza virus, and more Contributed by world-renown experts in the field

Small Animal Surgery Textbook E Book

Small Animal Surgery Textbook   E Book Book
Author : Theresa Welch Fossum
Publisher : Elsevier Health Sciences
Release : 2013-07-19
ISBN : 0323171214
Language : En, Es, Fr & De

GET BOOK

Book Description :

The fourth edition of Small Animal Surgery serves as a one-stop resource for authoritative information on all aspects of small animal surgery. Coverage includes basic procedures such as spays, castrations, and declaws, as well as more advanced surgeries like craniotomy, ventral slots, and lung lobectomy. New contributors bring a fresh perspective and discuss the latest advances in key areas such as imaging modalities, regenerative medicine, minimally invasive surgery, and neurology. Access to a companion website provides a fully searchable version of the book, bi-monthly content updates, videos, aftercare instructions, case presentations, and a fracture planner. Well illustrated, step-by-step instructions for surgical techniques provide quick reference to practical how-to information in emergency and clinical situations. Coverage of cutting-edge imaging techniques, including radiographs, CT, MRI, and digital imaging, explores the most useful imaging modalities for demonstrating areas of surgical concern. Access to the continually updated companion website for the life of this edition includes: Bi-monthly content updates provide cutting-edge information on surgery developments Video clips of step-by-step surgical procedures Customizable and printable aftercare instructions Interactive Fracture Planner Case presentations Neurosurgery video clips References linked to PubMed Over 1500 full color images offer exceptionally clear representations of anatomy and currently accepted surgical techniques, including approaches and closure. Anesthesia Protocols offer easy access to recommendations for anesthetizing animals with particular diseases or disorders. Notes boxes call attention to specific data, offering at-a-glance access to key information. A new chapter on neurologic examination provides a solid foundation in neuroanatomy, electro-diagnostics, and basic MRI physics and principles, enabling you to perform a proper neurologic exam to detect problems in cats and dogs, some of which can be corrected via surgical repair. A new chapter on regenerative medicine provides the most current information on stem cell research. Differential diagnosis tables and boxes offer quick access to vital information, including how to avoid misdiagnosis of disorders that may mimic more commonly encountered surgical neurologic problems that are not actual disorders requiring surgical repair.