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Introduction To Molecular Vaccinology

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Introduction to Molecular Vaccinology

Introduction to Molecular Vaccinology Book
Author : Matthias Giese
Publisher : Springer
Release : 2016-03-11
ISBN : 331925832X
Language : En, Es, Fr & De

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Book Description :

This textbook provides an easy-to-understand introduction to the complex topic of vaccine research and development. It gives a comprehensive though clearly arranged insight to the most important aspects of molecular vaccinology, leading from the basics in immunology, to design of vaccines and mode of action of vaccines to the actual formulation, manufacturing and registration of vaccines. The volume is therefore a valuable text about modern vaccinology for graduate students and a basic introduction for newcomers in vaccine design and development.

History of Vaccine Development

History of Vaccine Development Book
Author : Stanley A. Plotkin
Publisher : Springer Science & Business Media
Release : 2011-05-11
ISBN : 9781441913395
Language : En, Es, Fr & De

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Book Description :

Vaccinology, the concept of a science ranging from the study of immunology to the development and distribution of vaccines, was a word invented by Jonas Salk. This book covers the history of the methodological progress in vaccine development and to the social and ethical issues raised by vaccination. Chapters include "Jenner and the Vaccination against Smallpox," "Viral Vaccines," and "Ethical and Social Aspects of vaccines." Contributing authors include pioneers in the field, such as Samuel L. Katz and Hilary Koprowski. This history of vaccines is relatively short and many of its protagonists are still alive. This book was written by some of the chief actors in the drama whose subject matter is the conquest of epidemic disease.

Molecular Docking for Computer Aided Drug Design

Molecular Docking for Computer Aided Drug Design Book
Author : Mohane S. Coumar
Publisher : Academic Press
Release : 2021-03-01
ISBN : 0128223138
Language : En, Es, Fr & De

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Book Description :

Molecular Docking for Computer-Aided Drug Design: Fundamentals, Techniques, Resources and Applications offers in-depth coverage on the use of molecular docking for drug design. The book is divided into three main sections that cover basic techniques, tools, web servers and applications. It is an essential reference for students and researchers involved in drug design and discovery. Covers the latest information and state-of-the-art trends in structure-based drug design methodologies Includes case studies that complement learning Consolidates fundamental concepts and current practice of molecular docking into one convenient resource

How to Make a Vaccine

How to Make a Vaccine Book
Author : John Rhodes
Publisher : University of Chicago Press
Release : 2021-03-22
ISBN : 022679265X
Language : En, Es, Fr & De

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Book Description :

Distinguished expert in vaccine development John Rhodes tells the story of the first approved COVID-19 vaccines and offers an essential, up-to-the-minute primer on how scientists discover, test, and distribute vaccines. As the COVID-19 pandemic has affected every corner of the world, changing our relationship to our communities, to our jobs, and to each other, the most pressing question has been—when will it end? Researchers around the globe are urgently trying to answer this question by racing to test and distribute a vaccine that could end the greatest public health threat of our time. In How to Make a Vaccine, an expert who has firsthand experience developing vaccines tells an optimistic story of how three hundred years of vaccine discovery and a century and a half of immunology research have come together at this powerful moment—and will lead to multiple COVID-19 vaccines. Dr. John Rhodes draws on his experience as an immunologist, including working alongside a young Anthony Fauci, to unravel the mystery of how vaccines are designed, tested, and produced at scale for global deployment. Concise and accessible, this book describes in everyday language how the immune system evolved to combat infection, how viruses responded by evolving ways to evade our defenses, and how vaccines do their work. That history, and the pace of current research developments, make Rhodes hopeful that multiple vaccines will protect us. Today the complex workings of the immune system are well understood. The tools needed by biomedical scientists stand ready to be used, and more than 160 vaccine candidates have already been produced. But defeating COVID-19 won’t be the end of the story: Rhodes describes how discoveries today are also empowering scientists to combat future threats to global health, including a recent breakthrough in the development of genetic vaccines, which have never before been used in humans. As the world prepares for a vaccine, Rhodes offers a current and informative look at the science and strategies that deliver solutions to the crisis.

Molecular Vaccines

Molecular Vaccines Book
Author : Matthias Giese
Publisher : Springer Science & Business Media
Release : 2013-11-08
ISBN : 3319009788
Language : En, Es, Fr & De

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Book Description :

This title discusses all aspects of non-infectious and non-cancer– so called NINC – vaccines. Hypertension, diabetes and allergy vaccine development are referred to as well as the use of adjuvants and nanotechnology in vaccine development. The way of novel vaccines from bench to preclinical to clinical studies and launch to the market under EMEA (European Medicines Agency) and FDA (Food and Drug Administration) guidelines are described in-depth. The book is therefore of interest for researchers and clinicians engaged in vaccine development and molecular vaccine application.

Vaccinology

Vaccinology Book
Author : Alan D. T. Barrett
Publisher : John Wiley & Sons
Release : 2015-02-16
ISBN : 0470656166
Language : En, Es, Fr & De

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Book Description :

Vaccinology: An Essential Guide outlines in a clear, practical format the entire vaccine development process, from conceptualization and basic immunological principles through to clinical testing and licensing of vaccines. With an outstanding introduction to the history and practice of vaccinology, it also guides the reader through the basic science relating to host immune responses to pathogens. Covering the safety, regulatory, ethical, and economic and geographical issues that drive vaccine development and trials, it also presents vaccine delivery strategies, novel vaccine platforms (including experimental vaccines and pathogens), antigen development and selection, vaccine modelling, and the development of vaccines against emerging pathogens and agents of bioterror. There are also sections devoted to veterinary vaccines and associated regulatory processes. Vaccinology: An Essential Guide is a perfect tool for designed for undergraduate and graduate microbiologists and immunologists, as well as residents, fellows and trainees of infectious disease and vaccinology. It is also suitable for all those involved in designing and conducting clinical vaccine trials, and is the ideal companion to the larger reference book Vaccinology: Principles and Practice.

Molecular Biology

Molecular Biology Book
Author : Anonim
Publisher : Unknown
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Molecular Biology book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Critical Reviews in Immunology

Critical Reviews in Immunology Book
Author : Anonim
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Vaccine Analysis Strategies Principles and Control

Vaccine Analysis  Strategies  Principles  and Control Book
Author : Brian K. Nunnally,Vincent E. Turula,Robert D. Sitrin
Publisher : Springer
Release : 2014-11-27
ISBN : 3662450240
Language : En, Es, Fr & De

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Book Description :

This book is an indispensable tool for anyone involved in the research, development, or manufacture of new or existing vaccines. It describes a wide array of analytical and quality control technologies for the diverse vaccine modalities. Topics covered include the application of both classical and modern bio-analytical tools; procedures to assure safety and control of cross contamination; consistent biological transition of vaccines from the research laboratory to manufacturing scale; whole infectious attenuated organisms, such as live-attenuated and inactivated whole-cell bacterial vaccines and antiviral vaccines using attenuated or inactivated viruses; principles of viral inactivation and the application of these principles to vaccine development; recombinant DNA approaches to produce modern prophylactic vaccines; bacterial subunit, polysaccharide and glycoconjugate vaccines; combination vaccines that contain multiple antigens as well as regulatory requirements and the hurdles of licensure.

Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines

Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines Book
Author : Darren R. Flower,Yvonne Perrie
Publisher : Springer Science & Business Media
Release : 2012-12-09
ISBN : 1461450705
Language : En, Es, Fr & De

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Book Description :

This volume will address an important emergent area within the field of immunomics: the discovery of antigens and adjuvants within the context of reverse vaccinology. Conventional approaches to vaccine design and development requires pathogens to be cultivated in the laboratory and the immunogenic molecules within them to be identifiable. Conventional vaccinology is no longer universally successful, particularly for recalcitrant pathogens. By using genomic information we can study vaccine development in silico: 'reverse vaccinology', can identify candidate subunits vaccines by identifying antigenic proteins and by using equally rational approaches to identify novel immune response-enhancing adjuvants.

American Journal of Public Health

American Journal of Public Health Book
Author : Anonim
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Unlisted Drugs

Unlisted Drugs Book
Author : Anonim
Publisher : Unknown
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Research Communications in Molecular Pathology and Pharmacology

Research Communications in Molecular Pathology and Pharmacology Book
Author : Anonim
Publisher : Unknown
Release : 1995
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Tropical Infectious Diseases

Tropical Infectious Diseases Book
Author : Anonim
Publisher : Unknown
Release : 1999
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Bioinformatics for Vaccinology

Bioinformatics for Vaccinology Book
Author : Darren R. Flower
Publisher : John Wiley & Sons
Release : 2008-10-13
ISBN : 0470699825
Language : En, Es, Fr & De

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Book Description :

“... this book was written from start to finish by one extremely dedicated and erudite individual. The author has done an excellent job of covering the many topics that fall under the umbrella of computational biology for vaccine design, demonstrating an admirable command of subject matter in fields as disparate as object-oriented databases and regulation of T cell response. Simply put, it has just the right breadth and depth, and it reads well. In fact, readability is one of its virtues—making the book enticing and useful, all at once...” Human Vaccines, 2010 "... This book has several strong points. Although there are many textbooks that deal with vaccinology, few attempts have been made to bring together descriptions of vaccines in history, basic bioinformatics, various computational solutions and challenges in vaccinology, detailed experimental methodologies, and cutting-edge technologies... This book may well serve as a first line of reference for all biologists and computer scientists..." –Virology Journal, 2009 Vaccines have probably saved more lives and reduced suffering in a greater number of people than any other medical intervention in human history, succeeding in eradicating smallpox and significantly reducing the mortality and incidence of other diseases. However, with the emergence of diseases such as SARS and the threat of biological warfare, vaccination has once again become a topic of major interest in public health. Vaccinology now has at its disposal an array of post-genomic approaches of great power. None has a more persuasive potential impact than the application of computational informatics to vaccine discovery; the recent expansion in genome data and the parallel increase in cheap computing power have placed the bioinformatics exploration of pathogen genomes centre stage for vaccine researchers. This is the first book to address the area of bioinformatics as applied to rational vaccine design, discussing the ways in which bioinformatics can contribute to improved vaccine development by introducing the subject of harnessing the mathematical and computing power inherent in bioinformatics to the study of vaccinology putting it into a historical and societal context, and exploring the scope of its methods and applications. Bioinformatics for Vaccinology is a one-stop introduction to computational vaccinology. It will be of particular interest to bioinformaticians with an interest in immunology, as well as to immunologists, and other biologists who need to understand how advances in theoretical and computational immunobiology can transform their working practices.

Genetic Engineering News

Genetic Engineering News Book
Author : Anonim
Publisher : Unknown
Release : 2003
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Biographical Memoirs of Fellows of the Indian National Science Academy

Biographical Memoirs of Fellows of the Indian National Science Academy Book
Author : Indian National Science Academy
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Biographical Memoirs of Fellows of the Indian National Science Academy book written by Indian National Science Academy, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Progress in Immunology

Progress in Immunology Book
Author : Fritz Melchers,L. Nicklin,E.D. Albert,H. v. Boehmer,M.P. Dierich,L. Du Pasquier,K. Eichmann,D. Gemsa,O. Götze,J.R. Kalden,S.H.E. Kaufmann,H. Kirchner,K. Resch,G. Riethmüller,A. Schimpl,C. Sorg,M. Steinmetz,H. Wagner,H.G. Zachau
Publisher : Springer
Release : 1989-12-08
ISBN : 9783540510536
Language : En, Es, Fr & De

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Book Description :

Never has so much progress been reported in immunology as at this congress. The full impact of new technologies, developed since the late 1970s, has come to fruition: gene isolation, mutation, transfection and expression, protein structure and peptide synthesis, cell cloning, hybridization and monoclonal antibodies, CD serology, SCID and transgenic mice, modern immunomudulation and vaccines. An overwhelming mass of data has accumulated over the last years. The reports are up-to-date and outstanding, to a degree no journal will ever achieve, and the results are presented in a concise and lucid way. This report will serve as a guideline for generations of immunologists to come. Hundreds of new alleys have been opened, an abundance of research tools and goals are pointed to. This volume is a treasure trove of explorations ahead of our time - it is exciting reading. This progress report presents outstanding contributions, worth many prizes - a feature which is unusual for proceedings volumes. Immunology is exhibited at its best: an exciting research area and a rewarding subject to study for the benefit of mankind - today more than ever!

The New England Journal of Medicine

The New England Journal of Medicine Book
Author : Anonim
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Modulation of the Immune Response to Vaccine Antigens

Modulation of the Immune Response to Vaccine Antigens Book
Author : Fred Brown,Lars R. Haaheim,Universitetet i Bergen
Publisher : S Karger Ag
Release : 1998
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Leading specialists in the field present papers on a wide range of topics, including new adjuvants, mucosal immunity, new approaches to vaccine design, cytokines as immunomodulators, T-cell and B-cell responses, preclinical evaluation and in vivo models of immunity, and regulatory issues. Bringing the reader up to date on current trends in vaccine development, the study of vaccine-induced immune responses and mechanisms of immunity, this comprehensive volume provides an optimistic picture of solid progress in this difficult field and an outlook on future vaccine design.