Innovative Neuromodulation

Book Description :

Innovative Neuromodulation serves as an extensive reference that includes a basic introduction to the relevant aspects of clinical neuromodulation that is followed by an in-depth discussion of the innovative surgical and therapeutic applications that currently exist or are in development. This information is critical for neurosurgeons, neurophysiologists, bioengineers, and other proceduralists, providing a clear presentation of the frontiers of this exciting and medically important area of physiology. As neuromodulation remains an exciting and rapidly advancing field—appealing to many disciplines—the editors’ initial work (Essential Neuromodulation, 2011) is well complemented by this companion volume. Presents a comprehensive reference on the emerging field of neuromodulation that features chapters from leading physicians and researchers in the field Provides commentary for perspectives on different technologies and interventions to heal and improve neurological deficits Contains 300 full-color pages that begin with an overview of the clinical phases involved in neuromodulation, the challenges facing therapies and intraoperative procedures, and innovative solutions for better patient care

Book Description :

The possibility of harvesting the power of electric and magnetic impulses in the human body, commonly referred to as “neuromodulation,” is one of the most recent and promising developments of the modern science. Since the late ´60s, multiple invasive and non-invasive technologies have been developed and tested in experimental and clinical settings with the final aim of modulating the function of the central and peripheral nervous system. Clinical applications include, but are not limited to, common neurological disorders such as Parkinson’s disease and other movement disorders. The bulk of evidence supporting the clinical efficacy of various invasive and non-invasive approaches for neuromodulation has progressively led scientific societies, patients’ associations, and regulatory entities to acknowledge the critical role played by neuromodulation in the therapeutic algorithms of a wide range of neurological disorders. As a result, new technologies have been recently introduced into the market or are currently under validation. Their potential implementation into innovative protocols for neuromodulation demands a critical revision of what are the unmet needs for neuromodulation in movement disorders.

Book Description :

The study of neurofeedback and neuromodulation offer a window into brain physiology and function, suggesting innovative approaches to the improvement of attention, anxiety, pain, mood and behavior. Resources for understanding what neurofeedback and neuromodulation are, how they are used, and to what disorders and patients they can be applied are scarce, and this volume serves as an ideal tool for clinical researchers and practicing clinicians in both neuroscience and psychology to understand techniques, analysis, and their applications to specific patient populations and disorders. The top scholars in the field have been enlisted, and contributions offer both the breadth needed for an introductory scholar and the depth desired by a clinical professional. Includes the practical application of techniques to use with patients Includes integration of neurofeedback with neuromodulation techniques Discusses what the technique is, for which disorders it is effective, and the evidence basis behind its use Written at an appropriate level for clinicians and researchers

Book Description :

The Neuromodulation Casebook is a case-based volume for practical, hands-on decision-making using realistic case examples from the field of neuromodulation. It encompasses a variety of techniques and therapies, ranging from deep brain stimulation for a multitude of disorders, to spinal cord stimulation, peripheral nerve stimulation, cortical stimulation and cranial nerve stimulation, as well as non-invasive therapies and other implanted types of devices that interface with the nervous system. Allowing readers to better learn via case-based examples, this practical volume depicts real examples of decisions neuroscientists and neurosurgeons need to make every day from leaders in the field. This book serves as a companion text to the editor’s previous titles Essential Neuromodulation and Innovative Neuromodulation for neuroscience, neural engineering and biomedical engineering courses. Covers typical decision-making in the most frequent neuromodulation experiments and procedures across the widest array of scientists and practitioners Includes case-based chapters in an innovative, stepwise variant pathway format rather than being didactic in structure Provides for clinical, practical learning rather than serving as a reference on a particular topic

Book Description :

This book addresses all aspects of neuromodulation therapy in the management of headache and facial pain disorders, paying particular attention to the application of this rapidly growing and fascinating therapy to different forms of headache and facial pain conditions. It is divided into sections covering the principles of and rationale behind neuromodulation for headache, including in-depth discussions of challenging topics such as the definition of refractory headache and prognostic factors, and the technical aspects of devices used to modulate peripheral and central neuronal targets for the management of headaches. In addition, the book reviews the state-of-the art in current neuromodulation practice for headaches, discusses therapeutic strategies and therapy selection for each headache and facial pain disorder, and presents an in-depth, critical analysis of the published evidence, with sections covering innovative devices and emerging applications of novel neuromodulation technologies in the field. Gathering papers by internationally respected, leading experts, the book offers a unique guide to neuromodulation therapies in headache for neurologists, pain specialists, neurosurgeons, neuroscientists, trainees and general practitioners with an interest in headache and facial pain management.

Book Description :

Until recently, it was thought that the adult brain is modifiable only during early stages of ontogenesis. However, neurophysiological and neuroimaging studies now indicate that the mature human brain is, under certain conditions, capable of substantial neuroplastic changes. Neuroplasticity reflects the ability of the human brain to alter the pattern of neural activation in response to previous experience, and recent findings indicate that the effects of experience can lead to both structural as well as functional reorganization. It has been shown that pathological neuroplastic changes can be reverted/normalized and that the modulation of the neuroplastic changes can be paralleled by improvement of the patient's status. However, there is a gap between the potential of neuromodulation, technical progress and actual preparedness of medical personnel to provide this type of treatment. A prevalent opinion among medical professionals indicates that training programs and educational materials in neuromodulatory techniques are well needed and appreciated. Neuromodulation will focus on the description and discussion of methods currently available for invasive and non-invasive neuromodulation, their clinical potential, significance and practical applications. In order to facilitate understanding of the topic, the initial part of the textbook will review neurophysiological systems involved in neuromodulation and will provide readers with basic principles of neuroplasticity that constitutes the rationale for neuromodulation in human medicine. Additionally, the clinical use of these techniques will be described with special regard to safety and avoidance of complications.

Book Description :

Download Neuromodulation book written by Elliot Krames,P. Hunter Peckham,Ali R. Rezai, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Book Description :

Essential Neuromodulation, Second Edition is a concise reference covering all of the basic principles of neuromodulation in a single affordable volume for neuroscientists, residents, fellows, bioengineers and basic clinical practitioners. This second edition expands on developments in the field since 2011, emphasizing essential observations from all of the important clinical phases involved in any neuromodulation: targeting, intraoperative assessment, programming, complications and complication avoidance. As neuromodulation remains an exciting and rapidly advancing field, this information is critical for neurosurgeons, neurophysiologists, bioengineers and other proceduralists. Presents a comprehensive reference on the emerging field of neuromodulation that features chapters from leading physicians and researchers in the field Provides a cohesive presentation of neuromodulation technologies and interventions Contains 550 full-color pages that begin with an overview of the clinical phases involved in neuromodulation, the challenges facing therapies and intraoperative procedures, and innovative solutions for better patient care Emphasizes the fundamentals needed to embrace the neuromodulation field as a cohesive clinical entity Explores the use of electrical, chemical and mechanical interventions to heal and improve neurological deficits Covers the promise of neurostimulation for chronic pain, epilepsy, Parkinson’s disease, and other disorders and diseases Features developments in the field of neuromodulation since the first edition was published, including findings in lead, IPG and accessories

Book Description :

Neuromodulation is among the fastest-growing areas of medicine, involving many diverse specialties and affecting hundreds of thousands of patients with numerous disorders worldwide. It can briefly be described as the science of how electrical, chemical, and mechanical interventions can modulate the nervous system function. A prominent example of neuromodulation is deep brain stimulation (DBS), an intervention that reflects a fundamental shift in the understanding of neurological and psychiatric diseases: namely as resulting from a dysfunctional activity pattern in a defined neuronal network that can be normalized by targeted stimulation. The application of DBS has grown remarkably and more than 130,000 patients worldwide have obtained a DBS intervention in the past 30 years—most of them for treating movement disorders. This Frontiers Research Topics provides an overview on the current discussion beyond basic research in DBS and other brain stimulation technologies. Researchers from various disciplines, who are working on broader clinical, ethical and social issues related to DBS and related neuromodulation technologies, have contributed to this research topic.

Book Description :

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.

Book Description :

Every year, an estimated 1.7 million Americans sustain brain injury. Long-term disabilities impact nearly half of moderate brain injury survivors and nearly 50,000 of these cases result in death. Brain Neurotrauma: Molecular, Neuropsychological, and Rehabilitation Aspects provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma, including brain injury pathophysiology, biomarker research, experimental models of CNS injury, diagnostic methods, and neurotherapeutic interventions as well as neurorehabilitation strategies in the field of neurotraum research. The book includes several sections on neurotrauma mechanisms, biomarker discovery, neurocognitive/neurobehavioral deficits, and neurorehabilitation and treatment approaches. It also contains a section devoted to models of mild CNS injury, including blast and sport-related injuries. Over the last decade, the field of neurotrauma has witnessed significant advances, especially at the molecular, cellular, and behavioral levels. This progress is largely due to the introduction of novel techniques, as well as the development of new animal models of central nervous system (CNS) injury. This book, with its diverse coherent content, gives you insight into the diverse and heterogeneous aspects of CNS pathology and/or rehabilitation needs.

Book Description :

Download Women in Neuroscience book written by Marie-Ève Tremblay,Corette J. Wierenga,Elizabeth B. Torres,Liana Fattore,Arianna Maffei,Michela Chiappalone, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Book Description :

Download Deep Brain Stimulation Think Tank Updates in Neurotechnology and Neuromodulation Research book written by Michael S. Okun,James J. Giordano,Adolfo Ramirez-Zamora,Casey Halpern, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Book Description :

Handbook of Innovations in CNS Regenerative Medicine provides a comprehensive overview of the CNS regenerative medicine field. The book describes the basic biology and anatomy of the CNS and how injury and disease affect its balance and the limitations of the present therapies used in the clinics. It also introduces recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies. Finally, the book presents successful cases of translation of basic research to first-in-human trials and the steps needed to follow this path. Areas such as cell transplantation approaches, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies are key in regenerative medicine are covered in the book, along with regulatory and ethical issues. Describes the basic biology and anatomy of the CNS and how injury and disease affect its balance Discusses the limitations of present therapies used in the clinics Introduces the recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies, and enabling technologies Presents successful cases of translation of basic research to first-in-human trials, along with the steps needed to follow this path

Book Description :

This book focuses on the anatomy of the peripheral nervous system. Using the latest 3D-computer graphic modeling techniques, the author developed the innovative NEURO 3D LOCATORTM concept, which provides 3D in-vivo ultrasound images of peripheral nerve architectures, allowing readers to develop a mental real-time 3D GPS of the peripheral nervous system. This new edition is an extended version of the “Student edition” dedicated to Experts and is divided into three main parts: The first part describes fundamental concepts, from immunohistochemistry to limb innervation, and includes a detailed evaluation of the morphofunctional anatomy of the peripheral nerves. It also presents relevant data on neuromuscular transmission, from both classic and recent literature, to enable readers to gain an understanding the physiology and pathology of peripheral nerves as well as the prospects of repair. The second section addresses the upper limb, the brachial plexus and related peripheral nerves, while the third section focuses on the lower limb, the lumbosacral plexus and related peripheral nerves. By providing MRI sections related to the drawings and the descriptions of main nerve injuries, it facilitates radiological interpretation and clinical learning. The book also features detailed descriptions of surgical approaches and the ultrasound anatomy of the limbs, and includes supplementary material on applications to peripheral nerve stimulation, surgical procedures and interventional pain medicine techniques. Presenting high-quality 3D videos showing the progression of the ultrasound probe in real-time, synchronized with live ultrasound views and enhanced with anatomical computerized graphic layers, as well as over 500 outstanding full-color 2D and 3D illustrations, and access to than 100 practical videos, this unique book is a valuable resource for anesthesiologists, radiologists, orthopedic surgeons, neurosurgeons, neuromodulators, physiatrists, pain physicians and rheumatologists. It will also appeal to the medical community in general.

Book Description :

Neuromodulation: Comprehensive Textbook of Principles, Technologies, and Therapies, Second Edition, serves as a comprehensive and in-depth reference textbook covering all aspects of the rapidly growing field of neuromodulation. Since the publication of the first edition seven years ago, there has been an explosion of knowledge in neuromodulation, optogenetics, bioelectronics medicine and brain computer interfacing. Users will find unique discussions of the fundamental principles of neuromodulation and therapies, and how they are applied to the brain, spinal cord, peripheral nerves, autonomic nerves and various organs. The book focuses on comprehensive coverage of spinal cord stimulation, non-interventional and interventional brain stimulation, peripheral nerve stimulation, and the emerging fields of neuromodulation, including optogenetics and bioelectronics medicine. Provides a comprehensive reference that covers all aspects of the growing field of neuromodulation Written by international, leading authorities in their respective fields of neuromodulation, pain management, functional neurosurgery and biomedical engineering Includes new chapters on optogenetics, bioelectronics medicine and brain computer interfacing

Book Description :

Neurons use many modes of communication to transmit information besides what has come to be called neurotransmission. One of the most important of these is neuromodulation, where the signal from one neuron changes the properties of other neurons or synapses. This book provides the foundations for understanding the cellular and molecular basis for neuromodulatory effects. It goes on to illustrate some key examples of the roles played by neuromodulation in sensory processing, neuromuscular transmission, generation of motor behaviours, and learning.

Book Description :

Neuromodulation will be the first comprehensive and in-depth reference textbook covering all aspects of the rapidly growing field of neuromodulation. This book provides a complete discussion of the fundamental principles of neuromodulation and therapies applied to the brain, spinal cord, peripheral nerves, autonomic nerves and various organs. The textbook is highly structured and organized into overarching sections that cover chronic pain, movement disorders, psychiatric disorders, epilepsy, functional electrical stimulation, cardiac, gastrointestinal, genitourinary and organ neuromodulation. The fundamental principles of electricity and infusion, neural tissue interface, biomedical engineering, neuromodulation devices, basic science, neuroanatomy, neurophysiology, imaging and mechanisms are emphasized. In addition to providing details pertaining to the state-of-the-art current practice, innovative and emerging applications are discussed in specific chapters. Finally, the textbook provides specific chapters focusing on the technical aspects of the various neuromodulation procedures as well as technical specifications of various implantable devices. All of the contributors to Neuromodulation represent leading experts in the field. The editors are internationally renowned in their respective fields of neuromodulation, pain management, functional neurosurgery and biomedical engineering. Neuromodulation will be the first and foremost authoritative text on neuromodulation therapies and will establish the gold standard that defines the field for years to come. Key Features The first comprehensive reference on the emerging field of Neuromodulation Editors and authors include all leading figures in the field, and the leaders of the International Neuromodulation Society Over 90 chapters on topics ranging from a layout of the fundamentals (e.g. neuroanatomy, plasticity, bioelectrical effects, infusion therapies), solutions for the biomedical engineering challenges (e.g. materials, how to preserve normal function etc.), to a rundown of the existing applications and their future promise Over 1200 pages in splendid full color, richly illustrated Important areas of application include: control of chronic pain delivery of drugs to the nervous system via implanted devices control of epilepsy, Parkinson, etc. functional restoration, e.g. visual, auditory, restoration after stroke, restoration of motor function after traumatic events stimulation of body organs via neural devices (incl. the heart, abdominal organs, genitourinary organs) overview over newly emerging fields - control of obesity, blood pressure, tinnitus, brain injury, neurodegenerative diseases, brain-machine interfaces

Book Description :

This book draws on medical sociology and science and technology studies to develop a novel conceptual framework for understanding innovation processes, using the case study of deep brain stimulation in paediatric neurology. It addresses key questions, including: How are promising and potentially disruptive new health technologies integrated into busy resource-constrained clinical contexts? What activities are involved in establishing a new clinical service? How do social and cultural forces shape these services, and importantly, how are understandings of ‘health’ and ‘illness’ reconfigured in the process? The book explores how the ideals of patient-centred medicine influence innovation in the clinic, and it introduces the concept of patient-centred proto-platforms. It argues that patient-centred innovation can constitute an expansion of medical power, as the clinical gaze is directed not only towards the body but also towards the patient as a social being. This will be an innovative and insightful read for academics and advanced students, as well as health service researchers with an interest in technology adoption processes.

Book Description :

The Stimulated Brain—which garnered an Honorable Mention for Biomedicine & Neuroscience at the 2015 PROSE Awards from the Association of American Publishers—presents the first integration of findings on brain stimulation from different research fields with a primary focus on Transcranial Electrical Stimulation (tES), one of the most frequently used noninvasive stimulation methods. The last decade has witnessed a significant increase in the amount of research exploring how noninvasive brain stimulation can not only modulate but also enhance cognition and brain functions. However, although Transcranial Magnetic Stimulation (TMS) and particularly tES have the potential to become more widely applicable techniques (as they come with none of the risks associated with deep brain stimulation) the reference literature on these neurotechnologies has been sparse. This resource provides a broad survey of current knowledge, and also marks future directions in cognitive and neuro-enhancement. It expands our understanding of basic research findings from animals and humans, including clear translational benefits for applied research and the therapeutic use of noninvasive brain stimulation methods. The book's coverage includes a primer that paves the way to a more advanced knowledge of tES and its physiological basis; current research findings on cognitive and neuro-enhancement in animals and typical and atypical human populations, such as neurological patients; and discussions of future directions, including specific neuroethical issues and pathways for collaboration and entrepreneurialism. The Stimulated Brain is the first book to provide a comprehensive understanding of different aspects of noninvasive brain stimulation that are critical for scientists, clinicians, and those who are interested in “stimulating their minds by exploring this fascinating field of research. Honorable Mention for Biomedicine & Neuroscience in the 2015 PROSE Awards from the Association of American Publishers The only reference on the market to focus on transcranial electrical stimulation (tES) Coverage across technical, historical, and application topics makes this the single, comprehensive resource for researchers and students Edited book with chapters authored by international leaders in the fields of medicine, neuroscience, psychology, and philosophy—providing the broadest, most expert coverage available