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Inflammation And Immunity In Depression

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Inflammation and Immunity in Depression

Inflammation and Immunity in Depression Book
Author : Bernhard Baune
Publisher : Academic Press
Release : 2018-05-23
ISBN : 0128110740
Language : En, Es, Fr & De

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Book Description :

Inflammation and Immunity in Depression: Basic Science and Clinical Applications is the first book to move beyond the established theory of cytokine-induced depression and explore the broader role the immune system plays in this devastating mood disorder. The book fully explores the most recent lines of research into this rapidly advancing field, including alterations of T-cells, the neurobiological implications of neuroinflammation and immune alterations for brain development and function, and the genetic components of neuroinflammation in depression, including the relationships between stress and inflammation that are revealing gene-environment interactions in the disorder. Combining contributions from researchers worldwide, this book provides the most comprehensive discussion available today on the involvement of the innate immune and adaptive immune systems in depressive disorder. Chapters span neuroscience, psychology, clinical applications and future directions, making this book an invaluable resource for advanced students, researchers and practitioners who need to understand the complex and varied role of inflammation and immune responses in depression. Synthesizes current knowledge of inflammation and immunity in depression, ranging from basic neuroscience research, to clinical applications in psychiatry Expands on the long-established theory of cytokine-induced depression to discuss broader involvement of the immune system Explores translational potential of targeting immune dysfunction for clinical interventions

How to Feel Better

How to Feel Better Book
Author : Nick Hall
Publisher : Hachette UK
Release : 2016-09-13
ISBN : 146906541X
Language : En, Es, Fr & De

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Book Description :

Do you want to be more alert? Do you experience symptoms that have no obvious cause? Discover why countless health problems may have inflammation as a common denominator. Learn about the link between allergy and suicide, and how too much immunity can trigger depression and fatigue. Heart disease and cancer are also linked with too much immunity in the form of inflammation. But too little immunity can result in infection. This program will provide a clear understanding of how the immune system works and ways you can achieve a state of optimal health. Learn how stress and self destructive emotions can bring about infection and autoimmunity Understand how immune system cytokines can trigger depression and fatigue Learn how anti-inflammatory diets can lessen the pain of inflammation Discover how personality can predict flare-ups of autoimmunity

Inflammation Associated Depression Evidence Mechanisms and Implications

Inflammation Associated Depression  Evidence  Mechanisms and Implications Book
Author : Robert Dantzer,Lucile Capuron
Publisher : Springer
Release : 2016-12-28
ISBN : 3319511521
Language : En, Es, Fr & De

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Book Description :

Inflammation has invaded the field of psychiatry. The finding that cytokines are elevated in various affective and psychotic disorders brings to the forefront the necessity of identifying the precise research domain criteria (RDoCs) that inflammation is responsible for. This task is certainly the most advanced in major depressive disorders. The reason is that a dearth of clinical and preclinical studies has demonstrated that inflammation can cause symptoms of depression and conversely, cytokine antagonists can attenuate symptoms of depression in medical and psychiatric patients with chronic low grade inflammation. Important knowledge has been gained on the symptom dimensions that inflammation is driving and the mechanisms of action of cytokines in the brain, providing new targets for drug research and development. The aim of the book “Inflammation-Associated Depression” is to present this field of research and its implications in a didactic and comprehensive manner to basic and clinical scientists, psychiatrists, physicians, and students at the graduate level.

Immunopsychiatry

Immunopsychiatry Book
Author : Antonio L. Teixeira,Moises E. Bauer
Publisher : Oxford University Press, USA
Release : 2019-01-18
ISBN : 0190884460
Language : En, Es, Fr & De

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Book Description :

In recent years, a dedicated effort has been made to understand the immune dysfunction that is associated with major psychiatric disorders. The expanding knowledge of the immune system as a major homeostatic system has been very helpful in indicating new potential biomarkers and therapeutic targets to reduce the burden of psychiatric disorders. Indeed, immune cells, their secreted molecules, and cell signalling events are highly promising. Yet, the literature on immunology of psychiatric disorders is still dispersed, and only a few attempts have been made to consolidate the current knowledge in this expanding area. This book assembles and presents the available data on the immune/inflammatory dysfunction in psychiatric disorders, indicating the potential of immune mechanisms as either biomarkers or therapeutic targets, as well as discussing the challenges ahead of incorporating this knowledge into clinical practice. An international team of senior experts in the field review all psychiatric disorders in order to provide an integrated, in-depth understanding of the role of immune changes in psychiatric diseases for mental health clinicians as well as for researchers in immunology, psychiatry, neurology, and pharmacology.

Autism

Autism Book
Author : Abha Chauhan,Ved Chauhan,Ted Brown
Publisher : CRC Press
Release : 2009-10-26
ISBN : 9781420068870
Language : En, Es, Fr & De

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Book Description :

In 2007, the Centers for Disease Control and Prevention issued an autism alarm, estimating that one in 150 children may be affected by autism spectrum disorder. Autism has been treated mainly with technical approaches: principally applied behavior analysis and psychopharmacology. The findings in this book implicate oxidative stress as a common feature in autism, and support the claim that oxidative stress and intracellular redox imbalance can be induced or triggered in autism by exposure to certain environmental agents. Such findings could point the way to new treatment approaches in autism. Autism: Oxidative Stress, Inflammation, and Immune Abnormalities brings together a wealth of cutting-edge evidence that is already influencing how we treat this serious condition. It looks at the role of neuropathological abnormalities, genetics, and those factors common to oxidative stress such as inflammation, immune dysfunction, aberrant cellular signaling, and gene-environment interactions. Among dozens of research topics, this volume — Looks at interactions between genetic and environmental factors such as the maternal immune environment and prenatal/postnatal environmental stressors Summarizes evidence for oxidative damage and inflammation in autism Introduces a PDD behavior inventory as a tool for assessing autism Considers autism as an aberrant adaptive response to neuroinflammation and oxidative stress Examines the role of abnormal calcium signaling and the hypothesis that it may represent a target for novel therapeutics Presents a hypothesis that autism arises from the dysregulation of a unified gut/brain system rather than originating in the brain alone Proposes the utility of using a biopsychosocial method to treat autism This book shows us that autism is not only developmental but also a chronic condition based on active pathophysiology, and that it is not only behavioral but also presents somatic and systemic features. The findings in these chapters support the theory that oxidative stress plays an important role in autism. They also point to the value of conducting in-depth mechanistic studies as a way to uncover new targets for therapeutic intervention in autism.

Depressive Behaviors and Inflammation in Preschool Aged Children

Depressive Behaviors and Inflammation in Preschool Aged Children Book
Author : Gillian R. Acedo
Publisher :
Release : 2020
ISBN :
Language : En, Es, Fr & De

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Book Description :

Symptoms of depression, including sadness, irritability, loss of interest in activities, changes in sleep patterns, eating, and weight, and impairment in functioning, can emerge in early childhood and persist throughout the lifespan. However, distinguishing symptoms from typical behaviors of early childhood (e.g., sadness, irritability) is challenging. In addition to contributing to distress and impairment, depression is also associated negative physiological correlates. Psychosocial stressors such as depression can stimulate activation of immune responses. Specifically, people affected by depression experience longer healing times after injury, higher frequency of illness, and chronic inflammation. An association between chronic immune function dysregulation and depressive symptoms has been consistently found in research with adults, adolescents, and school-aged children. However, the relationship between depression and dysregulated inflammatory processes has not been investigated in young children. This study investigated an association between depressive behaviors and two inflammatory markers, interleukin 6 and interleukin 1 beta, in preschool-aged children. Measures included parent-report daily diaries to assess depressive behaviors and questionnaires to assess irritability, impairment, and health and sickness history in their children; laboratory-assessed negative emotionality (NA); and inflammatory markers measured via children’s saliva. It was hypothesized that higher levels of depressive behaviors, impairment, sickness, and negative emotionality would be associated with higher levels of inflammation in preschool-aged children. Additionally, this association was examined in exploratory analyses to identify the specific frequencies of depressive behaviors linked to inflammation. Results revealed no significant relations between depressive behaviors and inflammation, but found significant associations among chronic and acute sickness and depressive as well as demographic variables. Additionally, girls were more likely to experience acute illness than boys. No significant associations were found among other study variables. These findings suggest that the mechanism responsible for the association between depression and inflammation identified in older youth and adults may yet not be present or active in preschool-aged children. Future studies should continue to explore this association in young children as well as the acute immune response to depressive behaviors. These efforts can contribute to the broader goal of delineating typical, normative behaviors in early childhood from clinically significant behaviors to identify potential risk for the development of depression.

Bipolar Depression an Issue of Psychiatric Clinics of North America

Bipolar Depression  an Issue of Psychiatric Clinics of North America Book
Author : John L. Beyer
Publisher : Elsevier Health Sciences
Release : 2016-02-17
ISBN : 0323416616
Language : En, Es, Fr & De

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Book Description :

This issue of the Psychiatric Clinics edited by Dr. John Beyer is dedicated to the topic of Bipolar Depression, from the genetics of the disorder, to the therapeutic options, to treatment in special populations. Articles in this issue include, but are not limited to: Differences in Bipolar and Unipolar Depression, Suicide and Bipolar Disorder, Social Relationships, Support, and Life Events in Bipolar Disorder, Treatment of Bipolar Depression in Pregnancy and the Post-Partum Period, Psychotherapy for Bipolar Depression, Cognition, Dementia, and Bipolar Depression, and Genetics of Bipolar Disorder.

Neurobiology of Psychiatric Disorders

Neurobiology of Psychiatric Disorders Book
Author : Thomas E Schlaepfer,Charles B. Nemeroff
Publisher : Elsevier
Release : 2012-09-01
ISBN : 0444535004
Language : En, Es, Fr & De

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Book Description :

This new volume in the Handbook of Clinical Neurology presents a comprehensive review of the fundamental science and clinical treatment of psychiatric disorders. Advances in neuroscience have allowed for dramatic advances in the understanding of psychiatric disorders and treatment. Brain disorders, such as depression and schizophrenia, are the leading cause of disability worldwide. It is estimated that over 25% of the adult population in North America are diagnosed yearly with at least one mental disorder and similar results hold for Europe. Now that neurology and psychiatry agree that all mental disorders are in fact, "brain diseases," this volume provides a foundational introduction to the science defining these disorders and details best practices for psychiatric treatment. Provides a comprehensive review of the scientific foundations of psychiatric disorders and psychiatric treatment Includes detailed results from genetics, molecular biology, brain imaging, and neuropathological, immunological, epidemiological, metabolic, therapeutic and historical aspects of the major psychiatric disorders A "must have" reference and resource for neuroscientists, neurologists, psychiatrists, and clinical psychologists as well as all research scientists investigating disorders of the brain

Inflammation in Psychiatry

Inflammation in Psychiatry Book
Author : A. Halaris,B.E. Leonard
Publisher : Karger Medical and Scientific Publishers
Release : 2013-02-27
ISBN : 3318023116
Language : En, Es, Fr & De

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Book Description :

Psychoimmunology is a rapidly maturing area of scientific endeavor that provides a compelling integrative link between the immune system and its response to stress and psychiatric illness. Stress initiates pathological changes by activating the immune and endocrine systems. Inflammation is at the core of the complex and interactive systems that both contribute to and result from psychopathology. Consequently, inflammation research advances our knowledge of the pathology of depression, schizophrenia, chronic fatigue syndrome, posttraumatic stress disorder and a host of co-morbid conditions, notably diabetes, cardiovascular disease and cerebrovascular disease. The possible mechanisms underlying the bidirectionality of co-morbid medical and psychiatric disorders can be viewed as a consequence of inflammatory changes. These emerging novel concepts illustrate how the knowledge of inflammation can enable meaningful integration of psychopathology with physical co-morbidity. The innovative articles in this volume highlight the intricate link between psychiatry and psychoimmunology and underscore the central role of inflammation in furthering our understanding of the pathophysiology underlying mental health and illness.

Depression and Bipolar Disorder

Depression and Bipolar Disorder Book
Author : William Marchand
Publisher : Bull Publishing Company
Release : 2012-08-01
ISBN : 1936693399
Language : En, Es, Fr & De

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Book Description :

Responding to the reasons why people often do not recover from mood disorders, this book empowers readers by providing the tools needed to work effectively with doctors and health care providers to negotiate the complex pathway to a full and lasting recovery from depression or bipolar disorder. It explains the three main barriers to recovery—not receiving treatment, incorrect diagnosis, and receiving inadequate treatment—and how to overcome these challenges to ensure successful treatment. A practical book for the layperson, it provides flowcharts and useful forms to help readers determine whether they need help and how best to collaborate with their medical team.

Research Focus on Natural Products and the Body s Immune and Inflammatory Systems

Research Focus on Natural Products and the Body s Immune and Inflammatory Systems Book
Author : Kyoungho Suk
Publisher : Nova Publishers
Release : 2007
ISBN : 9781600217517
Language : En, Es, Fr & De

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Book Description :

The definition of 'natural' is 'produced or existing in nature.' Natural products refer to as any natural constituents, natural substances, or a group of the secondary metabolites that derive from plants, insects, marine plants and animals through their own metabolic pathways. Natural products are usually of high value and small quantity, and they have a variety of biological activities. Extensive research has been performed to understand the effects of natural products on the immune and inflammatory systems. However, the results have been published individually focusing on a particular aspect of immunity or inflammation. The readers in this field may benefit from a comprehensive review book that describes different aspects of immune/inflammatory responses together. This book provides an overview of how a variety of naturally occurring compounds may influence the body's immune and inflammatory systems with an emphasis on the actions of medicinal herbs. In this book, experts in each field present their recent data on the mechanisms by which natural products influence the immune and inflammatory responses. The experimental results that are described in this book are based on various in vitro as well as in vivo model systems. It is also discussed how such effects of natural products are related with their therapeutic applications for the treatment of immune and inflammatory diseases.

Depression An Issue of Psychiatric Clinics E Book

Depression  An Issue of Psychiatric Clinics   E Book Book
Author : David Mintz
Publisher : Elsevier Health Sciences
Release : 2012-03-26
ISBN : 1455743100
Language : En, Es, Fr & De

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Book Description :

This issue discusses the diagnosis and treatment of major depressive disorder (MDD) and other depressive disorders, with an emphasis on the psychosocial aspects of depression: how it affects societies, how it is affected by culture, and what the true meaning of recovery is for those suffering from MDD. The issue is divided into three section: Etiology, Diagnosis and Treatment. Authors address the evidence where biology and subjectivity meet. They discuss what is adaptive and what is pathologic and discuss population-based solutions that take into account the specificity of the individual. Authors also take into account combination treatments of psychotherapy and pharmacotherapy and weigh the treatment choices against specific patient subtypes.

Neuroimmunology of Sleep

Neuroimmunology of Sleep Book
Author : S. R. Pandi-Perumal,Daniel P. Cardinali,Georgios Chrousos
Publisher : Springer Science & Business Media
Release : 2007-08-19
ISBN : 0387691464
Language : En, Es, Fr & De

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Book Description :

This timely work reflects the growing importance of research into the nature of sleep and its medical aspects. One of the first of its kind, this work on the neuroimmunology of sleep provides an introduction to the interplay between these two key and interlinked areas. Written both from a basic and a clinical perspective, the volume is an invaluable information resource for biomedical professionals and students of the human biology. Highly practical guide written from both a basic and clinical perspective.

Moody Bitches

Moody Bitches Book
Author : Julie Holland
Publisher : Penguin
Release : 2015-03-03
ISBN : 069813642X
Language : En, Es, Fr & De

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Book Description :

A groundbreaking guide for women of all ages that shows women’s inherent moodiness is a strength, not a weakness As women, we learn from an early age that our moods are a problem. Bitches are moody. To succeed in life, we are told, we must have it all under control. We have to tamp down our inherent shifts in favor of a more static way of being. But our bodies are wiser than we imagine. Moods are not an annoyance to be stuffed away. They are a finely-tuned feedback system that, if heeded, can tell us how best to manage our lives. Our changing moods let us know when our bodies are primed to tackle different challenges and when we should be alert to developing problems. They help us select the right tool for each of our many jobs. If we deny our emotionality, we deny the breadth of our talents. With the right care of our inherently dynamic bodies, we can master our moods to avail ourselves of this great natural strength. Yet millions of American women are medicating away their emotions because our culture says that moodiness is a problem to be fixed. One in four of us takes a psychiatric drug. If you add sleeping pills to the mix, the statistics become considerably higher. Over-prescribed medications can have devastating consequences for women in many areas of our lives: sex, relationships, sleep, eating, focus, balance, and aging. And even if we don’t pop a pill, women everywhere are numbing their emotions with food, alcohol, and a host of addictive behaviors that deny the wisdom of our bodies and keep us from addressing the real issues that we face. Dr. Julie Holland knows there is a better way. She’s been sharing her frank and funny wisdom with her patients for years, and in Moody Bitches Dr. Holland offers readers a guide to our bodies and our moodiness that includes insider information about the pros and cons of the drugs we’re being offered, the direct link between food and mood, an honest discussion about sex, practical exercise and sleep strategies, as well as some surprising and highly effective natural therapies that can help us press the reset button on our own bodies and minds. In the tradition of Our Bodies, Our Selves, this groundbreaking guide for women of all ages will forge a much needed new path in women’s health—and offer women invaluable information on how to live better, and be more balanced, at every stage of life.

Encyclopedia of Behavioral Neuroscience

Encyclopedia of Behavioral Neuroscience Book
Author : N.A
Publisher : Elsevier
Release : 2010-06-03
ISBN : 0080453961
Language : En, Es, Fr & De

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Book Description :

Behavioral Neuroscientists study the behavior of animals and humans and the neurobiological and physiological processes that control it. Behavior is the ultimate function of the nervous system, and the study of it is very multidisciplinary. Disorders of behavior in humans touch millions of people’s lives significantly, and it is of paramount importance to understand pathological conditions such as addictions, anxiety, depression, schizophrenia, autism among others, in order to be able to develop new treatment possibilities. Encyclopedia of Behavioral Neuroscience is the first and only multi-volume reference to comprehensively cover the foundation knowledge in the field. This three volume work is edited by world renowned behavioral neuroscientists George F. Koob, The Scripps Research Institute, Michel Le Moal, Université Bordeaux, and Richard F. Thompson, University of Southern California and written by a premier selection of the leading scientists in their respective fields. Each section is edited by a specialist in the relevant area. The important research in all areas of Behavioral Neuroscience is covered in a total of 210 chapters on topics ranging from neuroethology and learning and memory, to behavioral disorders and psychiatric diseases. The only comprehensive Encyclopedia of Behavioral Neuroscience on the market Addresses all recent advances in the field Written and edited by an international group of leading researchers, truly representative of the behavioral neuroscience community Includes many entries on the advances in our knowledge of the neurobiological basis of complex behavioral, psychiatric, and neurological disorders Richly illustrated in full color Extensively cross referenced to serve as the go-to reference for students and researchers alike The online version features full searching, navigation, and linking functionality An essential resource for libraries serving neuroscientists, psychologists, neuropharmacologists, and psychiatrists

Understanding Depression

Understanding Depression Book
Author : Carmine Pariante
Publisher : Oxford University Press
Release : 2009-07-02
ISBN : 0199533075
Language : En, Es, Fr & De

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Book Description :

Depression is a major cause of morbidity throughout the world. This book brings together world leaders in research on depression, to discuss, for the first time, in an interdisciplinary setting, both classical and innovative ideas to understand this devastating disorder. It presents neurobiological, psychological, genetic and evolutionary models, with a particular emphasis on the mechanisms linking the brain to the endocrine and the immune systems, and thereforelinking depression to physical health.

Immunology and Psychiatry

Immunology and Psychiatry Book
Author : Norbert Müller,Aye-Mu Myint,Markus J. Schwarz
Publisher : Springer
Release : 2015-04-20
ISBN : 331913602X
Language : En, Es, Fr & De

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Book Description :

Psychiatric disorders are one of the most dramatic burdens for humankind. The role of immune dysfunction in the pathophysiology of these disorders has emerged during the last years, because there has been tremendous progress in psychoneuroimmunological research. Many results are presented here by pioneers in the field. The book addresses various effects of the immune system on the pathophysiology and course of psychiatric disorders and highlights the possible future impact on treatment decisions of various psychiatric disorders, including schizophrenia and depression. The contributions cover the role of in utero immune challenges on the development of schizophrenia, the role of infections, and autoimmune diseases and mild immune activation in the development of depression and schizophrenia, the influence of immune responses in other disorders such as Tourette's, Alzheimer's, and OCD, the connections between mental and physical pain as well as between anti-inflammatory and antipsychotic drugs.​

Cytokines

Cytokines Book
Author : Robert E. Faith,Anthony J. Murgo,Robert A. Good,Nicholas P. Plotnikoff
Publisher : CRC Press
Release : 2006-10-10
ISBN : 1420003801
Language : En, Es, Fr & De

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Book Description :

Cytokine involvement in the immune system's response to stress is now very well documented. Cytokine activity has been implicated in a variety of mental and physical diseases, and has been shown to have a significant role in fueling the vicious circle of depression and illness. The first edition of Cytokines: Stress and Immunity pointed out

Anti Inflammatory Diet

Anti Inflammatory Diet Book
Author : Daniel Plan
Publisher :
Release : 2020-05-04
ISBN :
Language : En, Es, Fr & De

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Book Description :

Reduce and Eliminate the Inflammation in Your Body with This HealthyDiet! Did you know that certain foods cause or facilitateinflammation? Have you been struggling to handle inflammation withmedicine to no avail? WHILE MEDICINE IS A MUST, A BAD DIETRENDERS IT LESS POWERFUL. LEARN HOW TO IMPROVE YOUR TREATMENT WITH THE ANTIINFLAMMATORY DIET! Inflammation is our body's response to fightingoff "foreign invaders". It's a useful reaction that ultimately makes us healthier. But, with somechronic conditions such as cancer, arthritis, diabetes, cardiovascular diseases and depression, inflammation can persist and become chronic. In these cases, your bestfriend and ally becomes the food you eat, not necessarily the medicine. At the very least, byavoiding inflammatory foods, you reduce the risks and potential for other health issues. Thisbook covers the topic of anti-inflammatory diets in detail. If you've been struggling withchronic inflammation, it's a MUST READ. You will learnabout: Inflammation - causes andtreatments The importance of a healthy diet in stavingoff diseases Anti-inflammatory foods and their manybenefits How to plan your anti-inflammatory diet so itsuits your needs Many health benefits of antiinflammatory diets Recipes, tips and SO MUCHMORE! The anti-inflammatory diet is a healthy diet thatincludes fruits, vegetables and fresh and raw food. Even if you're not struggling withinflammation, this book will help you prevent and control health issues before they arise. Youwill learn how to choose the right anti-inflammatory foods, causes, and correlations ofinflammation, and how to treat your body right through a properdiet! Ready to get healthy NOW? Scroll up, Click on 'Buy Now with 1-Click', and Get Your Copy!

Autophagy Cancer Other Pathologies Inflammation Immunity Infection and Aging

Autophagy  Cancer  Other Pathologies  Inflammation  Immunity  Infection  and Aging Book
Author : M. A. Hayat
Publisher : Academic Press
Release : 2017-09-07
ISBN : 0128121475
Language : En, Es, Fr & De

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Book Description :

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 12 discusses and details almost all aspects of the autophagy machinery in the context of health, cancer and other pathologies. Autophagy is more widely accepted as beneficial given its role in eliminating ‘toxic assets’ and promoting cell viability, hence, it has emerged as a new and potent modulator of disease progression that is both scientifically intriguing and clinically relevant. As the latest release in the Autophagy book series, users will find a detailed explanation of the role of molecular mechanisms. Presents the most advanced information regarding the role of the autophagic system in life and death States recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities Summarizes the most up-to-date findings on how autophagy is executed and regulated at the molecular level and how its disruption can lead to disease Authored by global leaders in the field, bringing the broadest, most expert coverage available