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Immunotherapy In Resistant Cancer

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Immunotherapy in Resistant Cancer From the Lab Bench Work to Its Clinical Perspectives

Immunotherapy in Resistant Cancer  From the Lab Bench Work to Its Clinical Perspectives Book
Author : Jorge Morales-Montor,Mariana Segovia-Mendoza
Publisher : Academic Press
Release : 2020-10-14
ISBN : 0128220295
Language : En, Es, Fr & De

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Book Description :

Immunotherapy in Resistant Cancer: From the Lab Bench Work to Its Clinical Perspectives provides high level knowledge on detailed mechanisms of actions and biological interactions of different immune drugs, with an aim of offering researchers and clinicians cutting-edge therapies to overcome drug resistance. The book explains the latest immunotherapies for different types of cancer, helping users carry out research projects or create alternatives for drug development in the pharmaceutical industry. Topics discussed include the relationship between immunotherapy and macrophages, immune checkpoints in different types of cancer, immune cocktails in solid tumors, and immune-phenotyping. Additionally, the book presents basic and clinical data on immunoresistance and glycosylation. This book is a valuable source for cancer researchers, medical doctors, clinicians and members of the biomedical field who must understand certain mechanisms to fight cancer that is resistant to immunotherapy. Provides basic and clinical evidence based on molecular interactions and clinical studies to address the risks and benefits of cancer immunotherapy Presents the results of new immunotherapy trials, discussing the state-of-the-art in different types of cancer Discusses targeted therapies approved by the FDA, along with therapies with clinical potential used in basic studies

Tumor Immunology and Immunotherapy

Tumor Immunology and Immunotherapy Book
Author : Robert C. Rees
Publisher : Oxford University Press, USA
Release : 2014-05-20
ISBN : 0199676860
Language : En, Es, Fr & De

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Book Description :

Patients are beginning to benefit from antibody based, cellular and vaccine approaches that are effective against genetically diverse and therapy-resistance cancers. BCG immunotherapy is now being used as a first line treatment for human bladder cancer and the introduction of prophylactic vaccination against Hepatitis B and HPV cancers is starting to show positive results. Following recent FDA approval for a vaccination against prostate cancer, and optimistic results in clinical trials for a vaccine targeting cancer antigens in lung cancer, cancer immunotherapy is now significantly impacting patient clinical management. Tumor Immunology and Immunotherapy provides an up-to-date and comprehensive account of cancer immunity and immunotherapy. It discusses our adaptive and innate immunity to cancer, the mechanisms underpinning our immune response, current approaches to cancer immunotherapy, and how tumour and host responses can circumvent effective anti-cancer immunity. The book examines recent results, publications and current areas of interest including 'immune editing' and the specific issues that are affecting the research and development of vaccines, providing insight into how these problems may be overcome, as viewed by world leaders in the field. Tumor Immunology and Immunotherapy will appeal to clinicians working in oncology and cancer immunotherapy, and research scientists including PhD and masters students, post-doctoral researchers and senior investigators.

Autophagy in Immune Response Impact on Cancer Immunotherapy

Autophagy in Immune Response  Impact on Cancer Immunotherapy Book
Author : Salem Chouaib
Publisher : Academic Press
Release : 2020-05
ISBN : 0128196092
Language : En, Es, Fr & De

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Book Description :

Autophagy in Immune Response: Impact on Cancer Immunotherapy focuses on the status and future directions of autophagy with respect to different aspects of its interaction with the immune system and immunotherapy. The book takes scientific research in autophagy a step further by presenting reputable information on the topic and offering integrated content with advancements in autophagy, from cell biology and biochemical research, to clinical treatments. This book is a valuable source for cancer researchers, oncologists, graduate students and several members of biomedical field who are interested in learning more on the relationship between autophagy and immunotherapies.

Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy

Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy Book
Author : Emmanuel Donnadieu
Publisher : Springer
Release : 2016-08-30
ISBN : 3319422235
Language : En, Es, Fr & De

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Book Description :

This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.The volume includes three sections. The first section covers general knowledge about T cell trafficking during a normal immune response but also during tumor development. The second section provides an in-depth description of the different obstacles that prevent T cells from migrating and contacting tumor cells. The third section explores therapeutic strategies to improve trafficking of T cells into tumors and, thus, to enhance the effectiveness of cancer immunotherapy.

Resistance of Cancer Cells to CTL Mediated Immunotherapy

Resistance of Cancer Cells to CTL Mediated Immunotherapy Book
Author : Benjamin Bonavida,Salem Chouaib
Publisher : Springer
Release : 2015-06-20
ISBN : 3319178075
Language : En, Es, Fr & De

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Book Description :

This comprehensive volume explores the latest research on the mechanisms of resistance in cancer cells to CTL-mediated immunotherapy. Chapter topics discuss cell-mediated immunity as the result of cytotoxic T-lymphocytes (CTL) directed specifically against cancer cells. In addition, the volume reviews how CTL mediate the cytotoxic activity, in large part, by the indication of apoptosis; hence, tumor cells develop anti-apoptotic mechanisms and thereby, resist CTL-induced apoptosis. In order for CTL-mediated antitumor immunotherapy to be effective, it is essential that agents directed against the resistant tumor cells sensitized cancer cells for CTL-mediated apoptosis. Examples of such agents discussed in the volume include are HDAC inhibitors, proteasome inhibitors, Bcl-2 family inhibitors, PARP, antibodies, and more.

Molecular Determinants of Prostate Tumor Resistance to Immunotherapy and Sensitization to Death Receptor mediated Apoptosis

Molecular Determinants of Prostate Tumor Resistance to Immunotherapy and Sensitization to Death Receptor mediated Apoptosis Book
Author : Chuen-Pei Ng
Publisher : Unknown
Release : 2001
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Molecular Determinants of Prostate Tumor Resistance to Immunotherapy and Sensitization to Death Receptor mediated Apoptosis book written by Chuen-Pei Ng, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Tumor Immunology and Immunotherapy Cellular Methods Part B

Tumor Immunology and Immunotherapy   Cellular Methods Part B Book
Author : Anonim
Publisher : Academic Press
Release : 2020-02-11
ISBN : 0128186755
Language : En, Es, Fr & De

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Book Description :

Tumor Immunology and Immunotherapy - Cellular Methods Part B, Volume 632, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Topics covered include Quantitation of calreticulin exposure associated with immunogenic cell death, Side-by-side comparisons of flow cytometry and immunohistochemistry for detection of calreticulin exposure in the course of immunogenic cell death, Quantitative determination of phagocytosis by bone marrow-derived dendritic cells via imaging flow cytometry, Cytofluorometric assessment of dendritic cell-mediated uptake of cancer cell apoptotic bodies, Methods to assess DC-dependent priming of T cell responses by dying cells, and more. Contains content written by authorities in the field Provides a comprehensive view on the topics covered Includes a high level of detail

Cancer Immunology Immunotherapy

Cancer Immunology  Immunotherapy Book
Author : Anonim
Publisher : Unknown
Release : 1991
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Cancer Immunology Immunotherapy book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Research Awards Index

Research Awards Index Book
Author : Anonim
Publisher : Unknown
Release : 2021-04-19
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Research Awards Index book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Reversal of Drug Resistance in Non Hodgkin s Lymphoma by Immunotherapy

Reversal of Drug Resistance in Non Hodgkin s Lymphoma by Immunotherapy Book
Author : Steve Anthony Alas
Publisher : Unknown
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Reversal of Drug Resistance in Non Hodgkin s Lymphoma by Immunotherapy book written by Steve Anthony Alas, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Cancer Immunology and Immunotherapy

Cancer Immunology and Immunotherapy Book
Author : Anonim
Publisher : Unknown
Release : 1986
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Cancer Immunology and Immunotherapy book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Biomedical Index to PHS supported Research pt A Subject access A H

Biomedical Index to PHS supported Research  pt  A  Subject access A H Book
Author : Anonim
Publisher : Unknown
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Biomedical Index to PHS supported Research pt A Subject access A H book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Cancer Stem Cell Resistance to Targeted Therapy

Cancer Stem Cell Resistance to Targeted Therapy Book
Author : Cristina Maccalli,Matilde Todaro,Soldano Ferrone
Publisher : Springer
Release : 2019-06-04
ISBN : 3030166244
Language : En, Es, Fr & De

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Book Description :

This book represents an up-dated summary of the state of the art of the characterization of cancer stem cell/ cancer initiating cell (CSC/CIC) properties. An overview of the definition and biological properties of CSCs/CICs as well as the role of these cells in determining the resistance to standard and immune-based therapies is provided. It also discusses limitations in the achievement of a definitive biological characterization of CSCs/CICs due to their high extent of plasticity and heterogeneity that is also mutually driven by the interaction of these cells with the tumor microenvironment. The limitations in targeting CSCs/CICs with immunotherapy are also explained together with explorative combination approaches that could increase the susceptibility of these cells to the recognition by immune cells. This book is conceived for a broad audience, including students, teachers, scientific experts. The critical revision of available results in terms of immunological profile of CSCs/CICs and the efficacy in targeting these cells by immunological approaches, results in a comprehensive and up to date recapitulation of the field and provides interesting suggestions on how to focus future investigations in order to assess the role of CSCs/CICs as prognostic and predictive biomarkers of responsiveness to therapies for cancer patients.

Progress in Cancer Chemo immunotherapy

Progress in Cancer Chemo immunotherapy Book
Author : Georges Mathé,Hamao Umezawa
Publisher : Unknown
Release : 1984
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Progress in Cancer Chemo immunotherapy book written by Georges Mathé,Hamao Umezawa, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Cancer Immunotherapy and Its Immunological Basis

Cancer Immunotherapy and Its Immunological Basis Book
Author : Yūichi Yamamura,Masayasu Kitagawa,Ichirō Azuma
Publisher : Unknown
Release : 1978
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Consists of the proceedings of international conference and symposia.

BCG in Cancer Immunotherapy

BCG in Cancer Immunotherapy Book
Author : Armand Frappier,Canadian Society for Immunology,Canadian Society of Microbiologists,Society of Microbiology of the Province of Quebec
Publisher : New York : Grune & Stratton
Release : 1976
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download BCG in Cancer Immunotherapy book written by Armand Frappier,Canadian Society for Immunology,Canadian Society of Microbiologists,Society of Microbiology of the Province of Quebec, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Specific Immunotherapy of Cancer with Vaccines

Specific Immunotherapy of Cancer with Vaccines Book
Author : Jean-Claude Bystryn,Soldano Ferrone,Philip Livingston
Publisher : Unknown
Release : 1993
ISBN : 9780897668262
Language : En, Es, Fr & De

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Book Description :

Download Specific Immunotherapy of Cancer with Vaccines book written by Jean-Claude Bystryn,Soldano Ferrone,Philip Livingston, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Journal of the National Cancer Institute

Journal of the National Cancer Institute Book
Author : Anonim
Publisher : Unknown
Release : 1999
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Journal of the National Cancer Institute book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.