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Immunologic Concepts In Transfusion Medicine

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Immunologic Concepts in Transfusion Medicine

Immunologic Concepts in Transfusion Medicine Book
Author : Robert W. Maitta
Publisher : Elsevier
Release : 2019-08-27
ISBN : 9780323675093
Language : En, Es, Fr & De

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Book Description :

Immunological Concepts in Transfusion Medicine provides a thorough discussion of the immune aspects of blood component transfusion, with in-depth information on the intricacies of immune responses to blood components and the immune processes that may be initiated in response to blood exposure. Written to increase knowledge and awareness of immune challenges such as alloimmunization and transfusion-related acute lung injury, this title bridges current basic scientific discoveries and the potential effects seen in blood recipients. Complies the knowledge and expertise of Dr. Robert Maitta, an expert in immune responses and antibody function/structure studies. Helps clinicians in the daily practice of caring for patients in need of transfusion support, as well as physicians in training when considering utilizing blood transfusions in a limited scope or in the setting of massive transfusion. Includes an immunology primer as an introduction to in-depth chapters covering allergic immune reactions to blood components, transfusion-related immunomodulation, fetal and neonatal alloimmune thrombocytopenia and neonatal neuthropenia, complications of haploidentical and mismatched HSC transplantation, chimeric antibody receptor therapies, and much more. Consolidates today's available information on this timely topic into a single, convenient resource.

Immunologic Concepts in Transfusion Medicine

Immunologic Concepts in Transfusion Medicine Book
Author : Robert W Maitta
Publisher : Elsevier Health Sciences
Release : 2019-08-27
ISBN : 0323675107
Language : En, Es, Fr & De

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Book Description :

Immunological Concepts in Transfusion Medicine provides a thorough discussion of the immune aspects of blood component transfusion, with in-depth information on the intricacies of immune responses to blood components and the immune processes that may be initiated in response to blood exposure. Written to increase knowledge and awareness of immune challenges such as alloimmunization and transfusion-related acute lung injury, this title bridges current basic scientific discoveries and the potential effects seen in blood recipients. Complies the knowledge and expertise of Dr. Robert Maitta, an expert in immune responses and antibody function/structure studies. Helps clinicians in the daily practice of caring for patients in need of transfusion support, as well as physicians in training when considering utilizing blood transfusions in a limited scope or in the setting of massive transfusion. Includes an immunology primer as an introduction to in-depth chapters covering allergic immune reactions to blood components, transfusion-related immunomodulation, fetal and neonatal alloimmune thrombocytopenia and neonatal neuthropenia, complications of haploidentical and mismatched HSC transplantation, chimeric antibody receptor therapies, and much more. Consolidates today’s available information on this timely topic into a single, convenient resource.

Immunology Guidebook

Immunology Guidebook Book
Author : Julius Cruse,Robert Lewis,Huan Wang
Publisher : Elsevier
Release : 2004-08-05
ISBN : 0080478425
Language : En, Es, Fr & De

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Book Description :

The Immunology Guidebook provides an easily accessible text-reference to the more up-to-date and difficult concepts in the complex science of immunology. It aims to demystify basic concepts and specialised molecular and cellular interactions. Its 18 chapters offer a logical and sequential presentation where much of the data is displayed in carefully designed tables. This book is intended for immunology students, researchers, practitioners and basic biomedical scientists. Tables provide a quick reference to ‘difficult to find' immunology data A distillate of the latest information on immunogenetics of the human MHC associated with tissue transplantation Information boxes featurw related web resources

Basic Applied Concepts of Blood Banking and Transfusion Practices E Book

Basic   Applied Concepts of Blood Banking and Transfusion Practices   E Book Book
Author : Kathy D. Blaney,Paula R. Howard
Publisher : Elsevier Health Sciences
Release : 2013-08-13
ISBN : 0323277438
Language : En, Es, Fr & De

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Book Description :

Using an easy-to-understand writing style, this text integrates immunohematology theory and application to provide you with the knowledge and skills you need to be successful in blood banking. Problem-solving exercises and case studies help you develop a solid understanding of all areas of blood banking. Learning objectives begin each chapter. Illustrated blood group boxes throughout chapter 6, Other Blood Group Systems, give the ISBT symbol, number, and the clinical significance of the antibodies at a glance. Margin notes and definitions in each chapter highlight important material and offer additional explanations. Chapter summaries recap the most important points of the chapter. Study questions at the end of each chapter provide an opportunity for review. Critical thinking exercises with case studies help you apply what you have learned in the chapter. UPDATED! Information and photos on automation include equipment actually used in the lab. Flow charts showing antibody detection and identification help you detect and identify antibodies. Advanced topics on Transplantation and Cellular Therapy, the HLA System, Molecular Techniques and Applications, Automation, Electronic Crossmatching, and Therapeutic Apheresis make the text relevant for 4-year MLS programs.

Textbook of Blood Banking and Transfusion Medicine

Textbook of Blood Banking and Transfusion Medicine Book
Author : Sally V. Rudmann
Publisher : Elsevier Health Sciences
Release : 2005-02-18
ISBN : 072160384X
Language : En, Es, Fr & De

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Book Description :

This comprehensive book on transfusion practices and immunohematology offers concise, thorough guidelines on the best ways to screen donors, store blood components, ensure safety, anticipate the potentially adverse affects of blood transfusion, and more. It begins with the basics of genetics and immunology, and then progresses to the technical aspects of blood banking and transfusion. Chapters are divided into sections on: Basic Science Review; Blood Group Serology; Donation, Preparation, and Storage; Pretransfusion Testing; Transfusion Therapy; Clinical Considerations; and Safety, Quality Assurance, and Data Management. Developed specifically for medical technologists, blood bank specialists, and residents, the new edition conforms to the most current standards of the American Association of Blood Banks (AABB). Expert Opinion essays, written by well-known, frequently published experts, discuss interesting topics of research or new advances in the field. Important terms are defined in the margins of the pages on which they appear, enabling readers to easily check the meaning of an unfamiliar term where it appears in context. Margin notes highlight important concepts and points, remind readers of previously discussed topics, offer an alternative perspective, or refer readers to other sources for further information. Material conforms to the most recent AABB standards for the most accurate, up-to-date information on immunohematology. Advanced concepts, beyond what is required for entry-level practice, are set apart from the rest of the text so readers can easily differentiate between basic and advanced information. A new chapter on Hematopoietic Stem Cells and Cellular Therapy (chapter 19) provides cutting-edge coverage of cellular therapy and its relevance to blood-banking. New content has been added on molecular genetics, component therapy, and International Society of Blood Transfusion (ISBT) nomenclature, as well as the latest information on HIV, hepatitis, quality assurance, and information systems. Coverage of new technologies, such as nucleic acid technology and gel technology, keeps readers current with advances in the field.

Clinical Principles of Transfusion Medicine

Clinical Principles of Transfusion Medicine Book
Author : Robert W Maitta
Publisher : Elsevier Health Sciences
Release : 2018-02-05
ISBN : 0323544592
Language : En, Es, Fr & De

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Book Description :

Offering a concise overview of transfusion medicine, including best practices for specific clinical settings, this practical resource by Dr. Robert W. Maitta covers the key information you need to know. Holistic, multidisciplinary coverage and a succinct, easy-to-read format make it essential reading for transfusion specialists, as well as practitioners in other specialties whose patients undergo blood transfusions. Covers the latest advancements in transfusion therapies, hematopoietic stem cells, infectious and non-infectious complications of transfusions, and future directions in transfusion medicine. Discusses special populations, including organ transplant patients; pediatric, obstetric, and geriatric patients; and patients undergoing emergency care. Consolidates fundamental clinical concepts and current practice of transfusion medicine into one convenient resource.

Molecular Protocols in Transfusion Medicine

Molecular Protocols in Transfusion Medicine Book
Author : Gregory A. Denomme,Maria Rios,Marion E. Reid
Publisher : Elsevier
Release : 2000-04-27
ISBN : 9780080536903
Language : En, Es, Fr & De

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Book Description :

This essential methods manual for immunohematologists (or hematologists and immunohematologists) provides information on genes that encode antigens on red blood cells, platelets and neutrophils. The book begins by covering general concepts in molecular biology and specific protocols such as DNA preparation, PCR-RFLP and allele-specific PCR. Information on the erythrocyte, platelet and neutrophil antigen systems and the molecular basis of polymorphisms are presented clearly in a gene facts sheet format. Database accession numbers and useful adjuncts such as Request forms, worksheets for PCR/enzyme digests also serve to benefit the user. The information is clearly presented and easily accessible and is complemented by the excellent diagrams and tabular material. This book is invaluable for both new and experienced researchers in the field and other related disciplines. Essential for hematologists and those involoved in tissue typing and the study of human genetic polymorphisms Presents clearly and concisely the information on a particular variant and the technique used to detect it Organized by antigen and provides sequences of polymorphisms and primers Details the general concepts and critical information on genes, their products, and sources of relevant nucleic acids Includes protocols that allow investigators to set up assays with minimal effort (protocols include primers, reagents, reaction conditions, sizes of amplified products, restriction fragment digests, and the relevant safety information) Provides information that helps interpret results in clinical settings Contains additional sources of information (e.g., key references, web site addresses, glossary, Database accession numbers, request forms, and worksheets for PCR/enzyme digests)

Transfusion Medicine Apheresis and Hemostasis

Transfusion Medicine  Apheresis  and Hemostasis Book
Author : Huy P. Pham,Lance A. Williams, III
Publisher : Academic Press
Release : 2017-09-15
ISBN : 0128040300
Language : En, Es, Fr & De

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Book Description :

Transfusion Medicine, Apheresis, and Hemostasis: Review Questions and Case Studies is the collaborative effort that spanned a time period of 2 years and included 50 experts, many whom are national leaders in their respected fields. It also represents the passion and privilege we feel to teach the next generation of physicians in Transfusion Medicine and Apheresis. The main goal for this book is to help the readers build a solid foundation of both basic and advanced conceptual knowledge to prepare for the American Board of Pathology (ABP) certification exam in Transfusion Medicine. This book is not intended to be a substitute for textbooks, original research or review articles, and/or clinical training. Further, since the field of medicine, both from a scientific and regulatory perspective, rapidly changes, the readers are advised to continuously update their knowledge by attending national meetings and reading clinical journals. To equip the readers with the basic knowledge in critical reading and data analysis, which is an essential skill in daily medical practice, a novel chapter titled “Data Interpretation in Laboratory Medicine was included in this book. In this chapter, the readers are asked to make logical conclusions based on the given data and/or statistical results. Moreover, there is also a chapter on “Practical Calculations in Transfusion Medicine, Apheresis, and Hemostasis to help consolidate all the necessary formulas commonly used in daily practice for easy reference. These chapters are unique to our book and will not be found in any other currently on the market. All of the questions in this book were originally created by the authors of each chapter. Each question can either be standalone or part of a case scenario representing challenge cases in Transfusion Medicine, Apheresis, and Hemostasis. These questions often represent both rare and common clinical scenarios that the authors have seen during their clinical practice. Each question is then followed by 5 possible answers, with only one being correct (or the best answer). After the question, there is a conceptual explanation followed by a more factual explanation of the right and wrong answers. We gave the individual authors the freedom to choose how they explained the wrong answer choices. Some authors chose to be more direct (e.g. Answer A is incorrect because...), while other authors chose a more conversational style (e.g. Human resources (answer A) includes staffing, selection, orientation, training, and competency assessment of employees). This format is designed to help the student linking the conceptual and factual knowledge together to form a solid foundation for use in clinical practice. At the end of each chapter, there is a list of articles and textbooks that will prove useful to the motivated student who wishes to become an expert in the field. Another special feature to our textbook is the presence of a pre-test and post-test, which are provided to help the readers with self-assessment. As stated above, the main focus of this book is to help the readers preparing for the ABP certification exam in Transfusion Medicine. However, due to the interdisciplinary nature of the field of Transfusion Medicine, Apheresis, and Hemostasis, we believe that this book is also beneficial to and can be used by all clinicians involved in the management of complex transfusion, apheresis, and hemostasis issues, such as hematologists, anesthesiologists, surgeons, and critical care physicians. We further believe that it is a helpful guide for these specialists to prepare for their own specialty certification exam, when the topics are related to Transfusion Medicine, Apheresis, and Hemostasis.

Blood Substitutes and Oxygen Biotherapeutics

Blood Substitutes and Oxygen Biotherapeutics Book
Author : Henry Liu,Alan D. Kaye,Jonathan S. Jahr
Publisher : Springer Nature
Release : 2022-09-12
ISBN : 3030959759
Language : En, Es, Fr & De

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Book Description :

This book functions as a comprehensive and authoritative reference book in blood transfusion and blood substitutes. It is a collection of the latest developments and the newest investigations, and individual chapters are written by world experts in the arena. The book begins with a historical review on the practice of transfusions as well as the components and physiology of blood. The following chapters cover various topics, including platelet substitutes, hemoglobin-based oxygen carriers, perfluorocarbon based oxygen carriers, and safety issues related to artificial hemoglobin. All chapters provide a bulleted highlights list to facilitate readers in mastering the main points of each individual chapter. Blood Substitutes and Oxygen Biotherapeutics is an invaluable reference book for perioperative care providers, hematologists, anesthesiologists, surgeons, obstetricians and gynecologists.

Mollison s Blood Transfusion in Clinical Medicine

Mollison s Blood Transfusion in Clinical Medicine Book
Author : Harvey G. Klein,David J. Anstee
Publisher : John Wiley & Sons
Release : 2008-04-15
ISBN : 0470986859
Language : En, Es, Fr & De

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Book Description :

“Both authors have dealt in an authoritative way withthe still rapidly expanding specialty and the eleventh edition ofthe book will be of the greatest value to all who are interested inthe scientific and practical aspects of blood transfusion inclinical medicine.” From the Foreword by Professor P.L. Mollison Highly respected, long-established book that has become the"bible" in transfusion medicine Why Buy This Book? Provides a sound basis for understanding modern transfusionmedicine Definitive reference source for any clinician involved withpatients requiring transfusion and for all staff working intransfusion services, immunohaematology laboratories and bloodbanks Highly practical advice on management issues for theclinician Completely revised and updated to reflect the rapid pace ofchange in transfusion medicine Written by two of the world's leading experts in the field

Blood Groups and Red Cell Antigens

Blood Groups and Red Cell Antigens Book
Author : Laura Dean
Publisher : Unknown
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Blood Groups and Red Cell Antigens book written by Laura Dean, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Clinical Immunology

Clinical Immunology Book
Author : Robert R. Rich,Thomas A. Fleisher,Harry W. Schroeder Jr.,Cornelia M. Weyand,David B. Corry,Jennifer M. Puck
Publisher : Elsevier
Release : 2022-09
ISBN : 9780702081651
Language : En, Es, Fr & De

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Book Description :

Offering unique, comprehensive coverage of both basic science and clinical scenarios, Clinical Immunology: Principles and Practice, 6th Edition, brings you up to date with every aspect of this fast-changing field. It examines the molecular, cellular, and immunologic bases of immunologic diseases and their broader systemic implications; it also includes complete coverage of common and uncommon immunologic disorders. Updated with all the latest immunologic research and clinical implications, including breakthrough immunotherapies and molecular-based treatment protocols, this fully revised edition provides authoritative guidance from some of the most respected global leaders in immunology in one complete, well-illustrated volume. Includes extensive revisions that reflect rapidly expanding research and clinical advances, including breakthrough drug and immunotherapies such as immune checkpoint inhibitors, immunotherapies for cancer, precision medicine, and transfusion medicine. Contains new chapters on COVID-19, immune responses, and the role of the immune system; immunoregulatory deficiencies; immune checkpoints; CAR T cells, including new cellular-based immunotherapy; gene therapy, including CRISPR and gene selection; and a clinically focused chapter on asthma. Provides new genetics content focused on data applications. Addresses notable advances in key areas such as the importance of the microbiota to normal immune system development and to the pathogenesis of immunologic and inflammatory diseases; relationships between the innate and adaptive immune systems; progress in rapid and cost-effective genomics; cell signaling pathways and the structure of cell-surface molecules; and many more. Covers hot topics such as the role of genetics and genomics in immune response and immunologic disease, atherosclerosis, recurrent fever syndromes, aging and deficiencies of innate immunity, the role of microbiota in normal immune system development and in the pathogenesis of immunologic and inflammatory diseases, and novel therapeutics. Features a user-friendly format with color-coded boxes highlighting critical information on Key Concepts, Clinical Pearls, Clinical Relevance, and Therapeutic Principles. Summarizes promising research and development anticipated over the next 5-10 years with On the Horizon boxes and discussions of translational research. An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.

Blood Banking and Transfusion Medicine

Blood Banking and Transfusion Medicine Book
Author : Christopher D. Hillyer,Leslie E. Silberstein,Paul M. Ness,Kenneth C. Anderson,John D. Roback
Publisher : Elsevier Health Sciences
Release : 2006-10-18
ISBN : 0443069816
Language : En, Es, Fr & De

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Book Description :

Ever since the discovery of blood types early in the last century, transfusion medicine has evolved at a breakneck pace. This second edition of Blood Banking and Transfusion Medicine is exactly what you need to keep up. It combines scientific foundations with today's most practical approaches to the specialty. From blood collection and storage to testing and transfusing blood components, and finally cellular engineering, you'll find coverage here that's second to none. New advances in molecular genetics and the scientific mechanisms underlying the field are also covered, with an emphasis on the clinical implications for treatment. Whether you're new to the field or an old pro, this book belongs in your reference library. Integrates scientific foundations with clinical relevance to more clearly explain the science and its application to clinical practice. Highlights advances in the use of blood products and new methods of disease treatment while providing the most up-to-date information on these fast-moving topics Discusses current clinical controversies, providing an arena for the discussion of sensitive topics. Covers the constantly changing approaches to stem cell transplantation and brings you the latest information on this controversial topic.

Clinical Immunology E Book

Clinical Immunology E Book Book
Author : Robert R. Rich,Thomas A. Fleisher,Harry W. Schroeder Jr.,Cornelia M. Weyand,David B. Corry,Jennifer M. Puck
Publisher : Elsevier Health Sciences
Release : 2022-08-23
ISBN : 0702081663
Language : En, Es, Fr & De

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Book Description :

Offering unique, comprehensive coverage of both basic science and clinical scenarios, Clinical Immunology: Principles and Practice, 6th Edition, brings you up to date with every aspect of this fast-changing field. It examines the molecular, cellular, and immunologic bases of immunologic diseases and their broader systemic implications; it also includes complete coverage of common and uncommon immunologic disorders. Updated with all the latest immunologic research and clinical implications, including breakthrough immunotherapies and molecular-based treatment protocols, this fully revised edition provides authoritative guidance from some of the most respected global leaders in immunology in one complete, well-illustrated volume. Includes extensive revisions that reflect rapidly expanding research and clinical advances, including breakthrough drug and immunotherapies such as immune checkpoint inhibitors, immunotherapies for cancer, precision medicine, and transfusion medicine. Contains new chapters on COVID-19, immune responses, and the role of the immune system; immunoregulatory deficiencies; immune checkpoints; CAR T cells, including new cellular-based immunotherapy; gene therapy, including CRISPR and gene selection; and a clinically focused chapter on asthma. Provides new genetics content focused on data applications. Addresses notable advances in key areas such as the importance of the microbiota to normal immune system development and to the pathogenesis of immunologic and inflammatory diseases; relationships between the innate and adaptive immune systems; progress in rapid and cost-effective genomics; cell signaling pathways and the structure of cell-surface molecules; and many more. Covers hot topics such as the role of genetics and genomics in immune response and immunologic disease, atherosclerosis, recurrent fever syndromes, aging and deficiencies of innate immunity, the role of microbiota in normal immune system development and in the pathogenesis of immunologic and inflammatory diseases, and novel therapeutics. Features a user-friendly format with color-coded boxes highlighting critical information on Key Concepts, Clinical Pearls, Clinical Relevance, and Therapeutic Principles. Summarizes promising research and development anticipated over the next 5–10 years with "On the Horizon" boxes and discussions of translational research.

Textbook of Blood Banking and Transfusion Medicine

Textbook of Blood Banking and Transfusion Medicine Book
Author : Sally V. Rudmann
Publisher : W B Saunders Company
Release : 2005-02-18
ISBN : 9781455734207
Language : En, Es, Fr & De

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Book Description :

This is a Pageburst digital textbook; the product description may vary from the print textbook. This comprehensive book on transfusion practices and immunohematology offers concise, thorough guidelines on the best ways to screen donors, store blood components, ensure safety, anticipate the potentially adverse affects of blood transfusion, and more. It begins with the basics of genetics and immunology, and then progresses to the technical aspects of blood banking and transfusion. Chapters are divided into sections on: Basic Science Review; Blood Group Serology; Donation, Preparation, and Storage; Pretransfusion Testing; Transfusion Therapy; Clinical Considerations; and Safety, Quality Assurance, and Data Management. Developed specifically for medical technologists, blood bank specialists, and residents, the new edition conforms to the most current standards of the American Association of Blood Banks (AABB). Expert Opinion essays, written by well-known, frequently published experts, discuss interesting topics of research or new advances in the field. Important terms are defined in the margins of the pages on which they appear, enabling readers to easily check the meaning of an unfamiliar term where it appears in context. Margin notes highlight important concepts and points, remind readers of previously discussed topics, offer an alternative perspective, or refer readers to other sources for further information. Material conforms to the most recent AABB standards for the most accurate, up-to-date information on immunohematology. Advanced concepts, beyond what is required for entry-level practice, are set apart from the rest of the text so readers can easily differentiate between basic and advanced information. A new chapter on Hematopoietic Stem Cells and Cellular Therapy (chapter 19) provides cutting-edge coverage of cellular therapy and its relevance to blood-banking. New content has been added on molecular genetics, component therapy, and International Society of Blood Transfusion (ISBT) nomenclature, as well as the latest information on HIV, hepatitis, quality assurance, and information systems. Coverage of new technologies, such as nucleic acid technology and gel technology, keeps readers current with advances in the field.

Basic Applied Concepts of Blood Banking and Transfusion Practices E Book

Basic   Applied Concepts of Blood Banking and Transfusion Practices   E Book Book
Author : Paula R. Howard
Publisher : Elsevier Health Sciences
Release : 2016-10-01
ISBN : 0323430619
Language : En, Es, Fr & De

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Book Description :

Basic & Applied Concepts of Blood Banking and Transfusion Practices, 4th Edition combines logically organized and updated content in a highly readable way that makes difficult concepts easy to understand. This essential text enables you to develop a solid understanding of all areas of blood banking by utilizing common theory, clinical scenarios, case studies, and critical-thinking exercises. Additional content on HIV testing, ABID panels, immunology and serology, HLA, and global blood banking keeps this book current so you’re learning the skills necessary to work in the modern lab. Further your knowledge with the QR codes in the margins that link to new images and websites. Illustrated blood group boxes provide you with the ISBT symbol, number, and the clinical significance of the antibodies at a glance throughout Chapter 7, Other Red Cell Blood Group Systems, Human Leukocyte Antigens, and Platelet Antigens. Study questions and critical thinking exercises give you an opportunity to review what you’ve learned. Margin notes and definitions highlight important material in each chapter and offer you additional help. Coverage of advanced topics includes transplantation and cellular therapy, the HLA system, molecular techniques and applications, automation, electronic cross-matching, and therapeutic apheresis. Chapter summaries recap the most important points of the chapter. Learning objectives help frame the chapter and set expectations. NEW! QR codes in the margins further learning by linking to new images or websites related to chapter content. NEW! Completely updated content prepares you to work in today’s clinical lab environment with lessons about HIV testing and confirmation rules from the CDC, ABID panels, immunology and serology, HLA, and global blood banking.

Hematopoietic Stem Cell Transplantation and Cellular Therapies for Autoimmune Diseases

Hematopoietic Stem Cell Transplantation and Cellular Therapies for Autoimmune Diseases Book
Author : Richard K. Burt,Dominique Farge,Milton A. Ruiz,Riccardo Saccardi,John A. Snowden
Publisher : CRC Press
Release : 2021-11-15
ISBN : 1351364758
Language : En, Es, Fr & De

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Book Description :

This book summarizes the global progress in medical and scientific research toward converting traditionally chronic autoimmune diseases into a drug-free reversible illness using hematopoietic stem cell transplantation (HSCT) and other cellular therapies such as T regulatory cells (Treg), mesenchymal stromal/stem cells, and chimeric antigen receptor T (CAR T) cells in order to reintroduce sustained immune tolerance. This title provides information on different types of stem cells and immune cells; post-transplant immune regeneration; cellular regulatory requirements; ethical and economic considerations; and the advantages and disadvantages of HSCT in the treatment of a variety of autoimmune diseases versus current conventional treatments. Arranged by disease, the text provides a comprehensive guide to HSCT for all types of autoimmune/immune disorders including monogenetic autoimmune diseases; autoimmune aplastic anemia; neurologic immune diseases including multiple sclerosis, chronic inflammatory demyelinating polyneuropathy, neuromyelitis optica, and stiff person syndrome; rheumatologic diseases such as systemic sclerosis and systemic lupus erythematosus; dermatologic diseases such as pemphigus; gastrointestinal disorders such as Crohn’s disease and celiac disease; and immune-mediated endocrinologic disease type I diabetes mellitus. Guidance is provided on the transplantation technique, cell collection and processing, conditioning regimens, infections, and early and late complications. Key Features Outlines therapies and techniques for HSCT for autoimmune diseases Discusses the advantages of HSCT over conventional therapies Reviews the entire process of stem cell therapy from harvest and ethics to indications, efficacy, and regulatory oversight

Good Manufacturing Practice in Transfusion Medicine

Good Manufacturing Practice in Transfusion Medicine Book
Author : C.Th. Smit Sibinga,P.C. Das,H.J. Heiniger
Publisher : Springer Science & Business Media
Release : 1994-08-31
ISBN : 9780792330097
Language : En, Es, Fr & De

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Book Description :

Transfusion medicine provides an excellent bridge connecting the healthy community donors with the patient's needs at the bedside; the dominant philosophy has been on patient care and science, but it is now realised that blood banks manufacture increasing amounts of blood components to administer to patients -- a role analogous to manufacturing functions. The concept of Good Manufacturing Practice (GMP) is therefore relatively new. While quality has always been important, the impact of GMP, Total Quality Management (TQM) and Quality Assurance (QA) will be profound. As the regulatory agencies, like the FDA in the U.S.A. and the EEC Commission in Europe, increase their enforcement activities, doctors, technical experts and managers will have to face many issues of quality assurance including documentation, validation, audit system, regulatory laws, licensing, teaching and training of staff and their job descriptions, standards, processing facilities, procedure validations, automation, record keeping, internal and external quality control of products and their release. The expansion of this philosophy to include Good Clinical Practice (GCP) is an even greater challenge demanding consensus therapy protocols and quality management of transfusion through auditing by the hospital transfusion committees. Such comprehensive plans will profoundly affect the financial and organisational structure of blood transfusion in the future.

Immunology and Serology in Laboratory Medicine

Immunology and Serology in Laboratory Medicine Book
Author : Mary Louise Turgeon
Publisher : Mosby
Release : 2017
ISBN : 9780323431477
Language : En, Es, Fr & De

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Book Description :

If you're looking to succeed in today's modern laboratory environment, then you need the insightful guidance found in Immunology & Serology in Laboratory Medicine, 6th Edition. Continuing to set the standard for comprehensive coverage of immunology, this must-have resource covers everything from mastering automated techniques to understanding immunoassay instrumentation and disorders of infectious and immunologic origin. As with previous editions, trusted author, teacher and former university program director, Mary Louise Turgeon helps you build a solid foundation of knowledge and skills by taking you from basic immunologic mechanisms and serologic concepts to the theory behind the procedures you will encounter in the lab. And now with a new full-color design, additional case studies, wealth of content updates, and new features, there's never been more reason to rely on Turgeon to stretch your critical thinking skills and fully prepare for success in the clinical lab. Comprehensive immunology coverage features the latest illustrations, photographs and summary tables to help clarify various concepts and information visually. Emphasis on critical thinking utilizes case studies to challenge readers to apply their knowledge to practice. Procedural protocols move readers from immunology theory to practical aspects of the clinical lab. Chapter highlights and review questions at the end of each chapter offer opportunities for review and self-assessment. Learning objectives and key terms at the beginning of each chapter outline the important vocabulary, information, and concepts found in the chapter. Glossary at the end of the book provides a quick reference to key terms and definitions. NEW! Full color diagrams and micrographs increases comprehension and gives readers a much better sense of what they will encounter in the lab. NEW! Updated content on vaccines, tumor immunology, transplant rejection, immunotherapies, instrumentation for molecular diagnosis, the immune response, and more ensures readers are prepared for immunology in today's clinical lab. NEW! Additional case studies allow readers to apply knowledge to real world situations and stretch their critical thinking skills. NEW! Reformatted chapter review questions reflect the multiple choice styles encountered on exams.

Rossi s Principles of Transfusion Medicine

Rossi s Principles of Transfusion Medicine Book
Author : Toby L. Simon,Eric A. Gehrie,Jeffrey McCullough,John D. Roback,Edward L. Snyder
Publisher : John Wiley & Sons
Release : 2022-08-15
ISBN : 1119719755
Language : En, Es, Fr & De

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Book Description :

ROSSI’S PRINCIPLES OF TRANSFUSION MEDICINE Transfusion Medicine impacts patients with hematologic, oncologic, and surgical conditions as well as all areas of critical care medicine and multiple areas of chronic care. This book aims to be the single best source for information related to any aspect or application of Transfusion Medicine. Contributors for the sixth edition have once again been drawn from various scientific, medical, and surgical disciplines. Thus, this book ranges from encouraging and managing donors, to collecting and preserving the blood, to matching it to the appropriate recipient, all the way to its clinical uses. It also extends these concepts to implantable tissue and regenerative medicine. Other sample topics covered within the work include: Contemporary issues in donation and transfusion: patient blood management, clinical and technical aspects of blood administration, and donor and patient Hemovigilance Blood components and derivatives: red blood cell metabolism, preservation and oxygen delivery, blood groups, and composition of plasma Apheresis, transplantation, and new therapies: hematopoietic growth factors, therapeutic phlebotomy and cellular apheresis, HLA antigens, alleles, and antibodies How Transfusion Medicine has been affected by the coronavirus pandemic, the role of pathogen reduction and other modern trends This book serves as a complete and comprehensive resource on Transfusion Medicine for clinicians who prescribe blood, students who expect to enter clinical practice, and for the scientists, physicians, nurses, technologists, and others who assure the quality and availability of blood services.