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Hyaluronan In Cancer Biology

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Hyaluronan in Cancer Biology

Hyaluronan in Cancer Biology Book
Author : Robert Stern
Publisher : Academic Press
Release : 2009-03-07
ISBN : 9780080921082
Language : En, Es, Fr & De

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Book Description :

Hyaluronan biology is being recognized as an important regulator of cancer progression. Paradoxically, both hyaluronan (HA) and hyaluronidases, the enzymes that eliminate HA, have also been correlated with cancer progression. Hyaluronan, a long-chain polymer of the extracellular matrix, opens up tissue spaces through which cancer cells move and metastasize. It also confers motility upon cells through interactions of cell-surface HA with the cytoskeleton. Embryonic cells in the process of movement and proliferation use the same strategy. It is an example of how cancer cells have commandeered normal cellular processes for their own survival and spread. There are also parallels between cancer and wound healing, cancer occasionally being defined as a wound that does not heal. The growing body of literature regarding this topic has recently progressed from describing the association of hyaluronan and hyaluronidase expression associated with different cancers, to understanding the mechanisms that drive tumor cell activation, proliferation, drug resistance, etc. No one source, however, discusses hyaluronan synthesis and catabolism, as well as the factors that regulate the balance. This book will offer a comprehensive summary and cutting-edge insight into Hyaluronan biology, the role of the HA receptors, the hyaluronidase enzymes that degrade HA, as well as HA synthesis enzymes and their relationship to cancer. * Offers a comprehensive summary and cutting-edge insight into Hyaluronan biology, the role of the HA receptors, the hyaluronidase enzymes that degrade HA, as well as HA synthesis enzymes and their relationship to cancer * Chapters are written by the leading international authorities on this subject, from laboratories that focus on the investigation of hyaluronan in cancer initiation, progression, and dissemination * Focuses on understanding the mechanisms that drive tumor cell activation, proliferation, and drug resistance

Cancer Research

Cancer Research Book
Author : Anonim
Publisher : Unknown
Release : 1999
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Cancer Research book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Chemistry and Biology of Hyaluronan

Chemistry and Biology of Hyaluronan Book
Author : Hari G. Garg,Charles A. Hales
Publisher : Elsevier
Release : 2004-07-14
ISBN : 9780080472225
Language : En, Es, Fr & De

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Book Description :

It was probably the French chemist Portes, who first reported in 1880 that the mucin in the vitreous body, which he named hyalomucine, behaved differently from other mucoids in cornea and cartilage. Fifty four years later Karl Meyer isolated a new polysaccharide from the vitreous, which he named hyaluronic acid. Today its official name is hyaluronan, and modern-day research on this polysaccharide continues to grow. Expertly written by leading scientists in the field, this book provides readers with a broad, yet detailed review of the chemistry of hyaluronan, and the role it plays in human biology and pathology. Twenty-seven chapters present a sequence leading from the chemistry and biochemistry of hyaluronan, followed by its role in various pathological conditions, to modified hylauronans as potential therapeutic agents and finally to the functional, structural and biological properties of hyaluronidases. Chemistry and Biology of Hyaluronan covers the many interesting facets of this fascinating molecule, and all chapters are intended to reach the wider research community. Comprehensive look at the chemistry and biology of hyaluronans Essential to Chemists, Biochemists and Medical researchers Broad yet detailed review of this rapidly growing research area

Encyclopedia of Cell Biology

Encyclopedia of Cell Biology Book
Author : Anonim
Publisher : Academic Press
Release : 2015-08-07
ISBN : 0123947960
Language : En, Es, Fr & De

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Book Description :

The Encyclopedia of Cell Biology offers a broad overview of cell biology, offering reputable, foundational content for researchers and students across the biological and medical sciences. This important work includes 285 articles from domain experts covering every aspect of cell biology, with fully annotated figures, abundant illustrations, videos, and references for further reading. Each entry is built with a layered approach to the content, providing basic information for those new to the area and more detailed material for the more experienced researcher. With authored contributions by experts in the field, the Encyclopedia of Cell Biology provides a fully cross-referenced, one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences. Fully annotated color images and videos for full comprehension of concepts, with layered content for readers from different levels of experience Includes information on cytokinesis, cell biology, cell mechanics, cytoskeleton dynamics, stem cells, prokaryotic cell biology, RNA biology, aging, cell growth, cell Injury, and more In-depth linking to Academic Press/Elsevier content and additional links to outside websites and resources for further reading A one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences

The Biology of Hyaluronan

The Biology of Hyaluronan Book
Author : CIBA Foundation Symposium
Publisher : John Wiley & Son Limited
Release : 1989-08-15
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Presents state-of-the-art applications in hyaluronan research, from hyaluronan's physicochemical properties to its clinical role as a connective tissue marker and its surgical implications, particularly in ear, eye and orthopaedic surgery. Covers hyaluronan's synthesis and catabolism, its role in cells, its interactions with specific binding proteins, and its role in the embryonic nervous system.

Role of Cancer Stem Cells in Cancer Biology and Therapy

Role of Cancer Stem Cells in Cancer Biology and Therapy Book
Author : Thomas Dittmar,Kurt S. Zänker
Publisher : CRC Press
Release : 2016-04-19
ISBN : 1466577363
Language : En, Es, Fr & De

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Book Description :

This book summarizes the latest findings about the role of cancer stem cells (CSCs) in cancer biology and how this knowledge could be used for novel anticancer therapies. It provides an overview of CSCs in selected malignancies with particular emphasis on hematopoietic neoplasias. It then reviews the role of CSCs in metastasis formation and initiation of cancer relapses. It also examines the dark side of cancer therapy such as conventional cancer therapies that may lead to the origin of recurrence CSCs. Finally, it supplies a brief overview of current concepts that may allow for a selective eradication of CSCs.

Cancer Metastasis Molecular and Cellular Mechanisms and Clinical Intervention

Cancer Metastasis  Molecular and Cellular Mechanisms and Clinical Intervention Book
Author : Wen G. Jiang,R.E. Mansel
Publisher : Springer Science & Business Media
Release : 2000-10-31
ISBN : 0792363957
Language : En, Es, Fr & De

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Book Description :

This book covers the molecular and cellular aspects of cancer metastasis, and discusses the clinical aspect of micro- and macro-metastases, which result in the death of the majority of patients with cancer. The current edition attempts to examine the current status of the basic scientific and clinical research in the area, and is a very useful reference for clinicians, oncologists, and biologists. It is intended for undergraduates as well as postgraduates in the area of medicine, oncology, and cancer biology.

The Journal of Cell Biology

The Journal of Cell Biology Book
Author : Anonim
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

No. 2, pt. 2 of November issue each year from v. 19 (1963)-47 (1970) and v. 55 (1972)- contain the Abstracts of papers presented at the Annual Meeting of the American Society for Cell Biology, 3d (1963)-10th (1970) and 12th (1972)-

Carbohydrates in chemistry and biology

Carbohydrates in chemistry and biology Book
Author : Beat Ernst,Gerald W. Hart,Pierre Sinaÿ
Publisher : Unknown
Release : 2000
ISBN : 9783527295111
Language : En, Es, Fr & De

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Book Description :

Download Carbohydrates in chemistry and biology book written by Beat Ernst,Gerald W. Hart,Pierre Sinaÿ, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Molecular Biology of the Cell

Molecular Biology of the Cell Book
Author : Anonim
Publisher : Unknown
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Molecular Biology of the Cell book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Determination of the Metastatic Potential of Ovarian Carcinoma Spheroids

Determination of the Metastatic Potential of Ovarian Carcinoma Spheroids Book
Author : Kathryn Maureen Burleson
Publisher : Unknown
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Determination of the Metastatic Potential of Ovarian Carcinoma Spheroids book written by Kathryn Maureen Burleson, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Anticancer Research

Anticancer Research Book
Author : Anonim
Publisher : Unknown
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Anticancer Research book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Hyaluronan Signaling and Turnover

Hyaluronan Signaling and Turnover Book
Author : Melanie Simpson,Paraskevi Heldin
Publisher : Academic Press
Release : 2014-07-26
ISBN : 0128003936
Language : En, Es, Fr & De

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Book Description :

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics. This volume covers hyaluronan signaling and turnover. Provides information on cancer research Outstanding and original reviews Suitable for researchers and students

Acta Biologica Cracoviensia

Acta Biologica Cracoviensia Book
Author : Anonim
Publisher : Unknown
Release : 2003
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Acta Biologica Cracoviensia book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Endogenous Hyaluronan During Corneal Healing

Endogenous Hyaluronan During Corneal Healing Book
Author : Nils Molander
Publisher : Unknown
Release : 1994
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Endogenous Hyaluronan During Corneal Healing book written by Nils Molander, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

International Journal of Oncology

International Journal of Oncology Book
Author : Anonim
Publisher : Unknown
Release : 2007-11
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download International Journal of Oncology book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Chemistry Biology and Medical Applications of Hyaluronan and Its Derivatives

The Chemistry  Biology and Medical Applications of Hyaluronan and Its Derivatives Book
Author : T. C. Laurent
Publisher : Portland Press, London
Release : 1998
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The aim of this book is to collect within one volume information on hyaluronan. This polysaccharide has received rapid attention for two reasons: it has important regulative functions within cell biology; and it has become a commercially important product because of its use in ophthalmic surgery and treatment of joint diease. A number of other practical applications are also discussed. The book covers various aspects of hyaluronan from the structure and chemistry of the polymer to its metabolism, cell biological interactions, behaviour in pathological processes, and potentially new medical applications.

Investigation of hyaluronan synthase function during mouse development

Investigation of hyaluronan synthase function during mouse development Book
Author : Janet Yuetsim Lee Tien
Publisher : Unknown
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Investigation of hyaluronan synthase function during mouse development book written by Janet Yuetsim Lee Tien, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Detection of Hyaluronan and Hyaluronidase in Human Whole Saliva and Parotid Saliva

Detection of Hyaluronan and Hyaluronidase in Human Whole Saliva and Parotid Saliva Book
Author : Mari-Anne L. Low
Publisher : Unknown
Release : 1994
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Detection of Hyaluronan and Hyaluronidase in Human Whole Saliva and Parotid Saliva book written by Mari-Anne L. Low, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.