Skip to main content

Hyaluronan In Cancer Biology

In Order to Read Online or Download Hyaluronan In Cancer Biology Full eBooks in PDF, EPUB, Tuebl and Mobi you need to create a Free account. Get any books you like and read everywhere you want. Fast Download Speed ~ Commercial & Ad Free. We cannot guarantee that every book is in the library!

Hyaluronan in Cancer Biology

Hyaluronan in Cancer Biology Book
Author : Robert Stern
Publisher : Academic Press
Release : 2009-03-07
ISBN : 9780080921082
Language : En, Es, Fr & De

GET BOOK

Book Description :

Hyaluronan biology is being recognized as an important regulator of cancer progression. Paradoxically, both hyaluronan (HA) and hyaluronidases, the enzymes that eliminate HA, have also been correlated with cancer progression. Hyaluronan, a long-chain polymer of the extracellular matrix, opens up tissue spaces through which cancer cells move and metastasize. It also confers motility upon cells through interactions of cell-surface HA with the cytoskeleton. Embryonic cells in the process of movement and proliferation use the same strategy. It is an example of how cancer cells have commandeered normal cellular processes for their own survival and spread. There are also parallels between cancer and wound healing, cancer occasionally being defined as a wound that does not heal. The growing body of literature regarding this topic has recently progressed from describing the association of hyaluronan and hyaluronidase expression associated with different cancers, to understanding the mechanisms that drive tumor cell activation, proliferation, drug resistance, etc. No one source, however, discusses hyaluronan synthesis and catabolism, as well as the factors that regulate the balance. This book will offer a comprehensive summary and cutting-edge insight into Hyaluronan biology, the role of the HA receptors, the hyaluronidase enzymes that degrade HA, as well as HA synthesis enzymes and their relationship to cancer. * Offers a comprehensive summary and cutting-edge insight into Hyaluronan biology, the role of the HA receptors, the hyaluronidase enzymes that degrade HA, as well as HA synthesis enzymes and their relationship to cancer * Chapters are written by the leading international authorities on this subject, from laboratories that focus on the investigation of hyaluronan in cancer initiation, progression, and dissemination * Focuses on understanding the mechanisms that drive tumor cell activation, proliferation, and drug resistance

Chemistry and Biology of Hyaluronan

Chemistry and Biology of Hyaluronan Book
Author : Hari G. Garg,Charles A. Hales
Publisher : Elsevier
Release : 2004-07-14
ISBN : 9780080472225
Language : En, Es, Fr & De

GET BOOK

Book Description :

It was probably the French chemist Portes, who first reported in 1880 that the mucin in the vitreous body, which he named hyalomucine, behaved differently from other mucoids in cornea and cartilage. Fifty four years later Karl Meyer isolated a new polysaccharide from the vitreous, which he named hyaluronic acid. Today its official name is hyaluronan, and modern-day research on this polysaccharide continues to grow. Expertly written by leading scientists in the field, this book provides readers with a broad, yet detailed review of the chemistry of hyaluronan, and the role it plays in human biology and pathology. Twenty-seven chapters present a sequence leading from the chemistry and biochemistry of hyaluronan, followed by its role in various pathological conditions, to modified hylauronans as potential therapeutic agents and finally to the functional, structural and biological properties of hyaluronidases. Chemistry and Biology of Hyaluronan covers the many interesting facets of this fascinating molecule, and all chapters are intended to reach the wider research community. Comprehensive look at the chemistry and biology of hyaluronans Essential to Chemists, Biochemists and Medical researchers Broad yet detailed review of this rapidly growing research area

Encyclopedia of Cell Biology

Encyclopedia of Cell Biology Book
Author : N.A
Publisher : Academic Press
Release : 2015-08-07
ISBN : 0123947960
Language : En, Es, Fr & De

GET BOOK

Book Description :

The Encyclopedia of Cell Biology offers a broad overview of cell biology, offering reputable, foundational content for researchers and students across the biological and medical sciences. This important work includes 285 articles from domain experts covering every aspect of cell biology, with fully annotated figures, abundant illustrations, videos, and references for further reading. Each entry is built with a layered approach to the content, providing basic information for those new to the area and more detailed material for the more experienced researcher. With authored contributions by experts in the field, the Encyclopedia of Cell Biology provides a fully cross-referenced, one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences. Fully annotated color images and videos for full comprehension of concepts, with layered content for readers from different levels of experience Includes information on cytokinesis, cell biology, cell mechanics, cytoskeleton dynamics, stem cells, prokaryotic cell biology, RNA biology, aging, cell growth, cell Injury, and more In-depth linking to Academic Press/Elsevier content and additional links to outside websites and resources for further reading A one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences

Role of Cancer Stem Cells in Cancer Biology and Therapy

Role of Cancer Stem Cells in Cancer Biology and Therapy Book
Author : Thomas Dittmar,Kurt S. Zänker
Publisher : CRC Press
Release : 2016-04-19
ISBN : 1466577363
Language : En, Es, Fr & De

GET BOOK

Book Description :

This book summarizes the latest findings about the role of cancer stem cells (CSCs) in cancer biology and how this knowledge could be used for novel anticancer therapies. It provides an overview of CSCs in selected malignancies with particular emphasis on hematopoietic neoplasias. It then reviews the role of CSCs in metastasis formation and initiation of cancer relapses. It also examines the dark side of cancer therapy such as conventional cancer therapies that may lead to the origin of recurrence CSCs. Finally, it supplies a brief overview of current concepts that may allow for a selective eradication of CSCs.

Viscosupplementation Agents Advances in Research and Application 2011 Edition

Viscosupplementation Agents  Advances in Research and Application  2011 Edition Book
Author : N.A
Publisher : ScholarlyEditions
Release : 2012-01-09
ISBN : 1464947368
Language : En, Es, Fr & De

GET BOOK

Book Description :

Viscosupplementation Agents: Advances in Research and Application: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Viscosupplementation Agents in a compact format. The editors have built Viscosupplementation Agents: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Viscosupplementation Agents in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Viscosupplementation Agents: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Hyaluronan Signaling and Turnover

Hyaluronan Signaling and Turnover Book
Author : Melanie Simpson,Paraskevi Heldin
Publisher : Academic Press
Release : 2014-07-26
ISBN : 0128003936
Language : En, Es, Fr & De

GET BOOK

Book Description :

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics. This volume covers hyaluronan signaling and turnover. Provides information on cancer research Outstanding and original reviews Suitable for researchers and students

The Biology of Hyaluronan

The Biology of Hyaluronan Book
Author : David Evered,Julie Whelan
Publisher : John Wiley & Sons
Release : 2008-04-30
ISBN : 0470513780
Language : En, Es, Fr & De

GET BOOK

Book Description :

Presents state-of-the-art applications in hyaluronan research, from hyaluronan's physicochemical properties to its clinical role as a connective tissue marker and its surgical implications, particularly in ear, eye and orthopaedic surgery. Covers hyaluronan's synthesis and catabolism, its role in cells, its interactions with specific binding proteins, and its role in the embryonic nervous system.

The Chemistry Biology and Medical Applications of Hyaluronan and Its Derivatives

The Chemistry  Biology and Medical Applications of Hyaluronan and Its Derivatives Book
Author : T. C. Laurent
Publisher : Portland Press, London
Release : 1998
ISBN :
Language : En, Es, Fr & De

GET BOOK

Book Description :

The aim of this book is to collect within one volume information on hyaluronan. This polysaccharide has received rapid attention for two reasons: it has important regulative functions within cell biology; and it has become a commercially important product because of its use in ophthalmic surgery and treatment of joint diease. A number of other practical applications are also discussed. The book covers various aspects of hyaluronan from the structure and chemistry of the polymer to its metabolism, cell biological interactions, behaviour in pathological processes, and potentially new medical applications.

Tumor Microenvironment

Tumor Microenvironment Book
Author : Alexander Birbrair
Publisher : Springer Nature
Release : 2020-04-07
ISBN : 3030401464
Language : En, Es, Fr & De

GET BOOK

Book Description :

Revealing essential roles of the tumor microenvironment in cancer progression, this volume focuses on the extracellular matrix components of the tumor during cancer development. Further, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include heparan sulphate, hyaluronan, fibronectin, perlecan, glypican, matrix metalloproteinases, and much more. Taken alongside its companion volumes, Tumor Microenvironment: Extracellular Matrix Components – Part A updates us on what we know about the different aspects of the tumor microenvironment, as well as apprises us on the future advances in the field. For the newest generation of researchers, this volume serves as a useful introduction to the history of scientists’ focus on the tumor microenvironment, and explores how this knowledge is currently applied in cancer treatments. The book is an essential text for advanced cell biology and cancer biology students, as well as for scientists seeking an update on the developments in tumor microenvironment research. All of the chapter authors are renowned international experts in the field of cancer biology, and in the specific subfields that are the focus of their chapters.

Extracellular Matrix in Tumor Biology

Extracellular Matrix in Tumor Biology Book
Author : Rolf A. Brekken,Dwayne Stupack
Publisher : Springer
Release : 2017-08-04
ISBN : 3319609076
Language : En, Es, Fr & De

GET BOOK

Book Description :

This volume provides an overview on the influence of Extracellular Matrix (ECM) on tumor progression. It covers topics such as signaling induced by structural ECM proteins including collagen and fibronectin, the control of ECM deposition and the turnover in tumors. Also discussed are the migration of cells through basement membranes and the function of proteoglycans including lumican and veriscan in tumor progression. Biomaterial-based in-vitro models as well as C. elegans models of the tumor microenvironment are used to show how these models can lead to a greater understanding of the disease mechanisms that promote cancer progression. The book addresses researchers working on cancer biology or ECM, and oncologists alike.

Abeloff s Clinical Oncology E Book

Abeloff s Clinical Oncology E Book Book
Author : John E. Niederhuber,James O. Armitage,James H Doroshow,Michael B. Kastan,Joel E. Tepper
Publisher : Elsevier Health Sciences
Release : 2013-09-12
ISBN : 1455728810
Language : En, Es, Fr & De

GET BOOK

Book Description :

Practical and clinically focused, Abeloff’s Clinical Oncology is a trusted medical reference book designed to capture the latest scientific discoveries and their implications for cancer diagnosis and management of cancer in the most accessible manner possible. Abeloff’s equips everyone involved - from radiologists and oncologists to surgeons and nurses - to collaborate effectively and provide the best possible cancer care. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Select the most appropriate tests and imaging studies for cancer diagnosis and staging of each type of cancer, and manage your patients in the most effective way possible by using all of the latest techniques and approaches in oncology. Enhance your understanding of complex concepts with a color art program that highlights key points and illustrates relevant scientific and clinical problems. Stay at the forefront of the latest developments in cancer pharmacology, oncology and healthcare policy, survivorship in cancer, and many other timely topics. See how the most recent cancer research applies to practice through an increased emphasis on the relevance of new scientific discoveries and modalities within disease chapters. Streamline clinical decision making with abundant new treatment and diagnostic algorithms as well as concrete management recommendations. Take advantage of the collective wisdom of preeminent multidisciplinary experts in the field of oncology, including previous Abeloff’s editors John E. Niederhuber, James O. Armitage, and Michael B. Kastan as well as new editors James H. Doroshow from the National Cancer Institute and Joel E. Tepper of Gunderson & Tepper: Clinical Radiation Oncology. Quickly and effortlessly access the key information you need with the help of an even more user-friendly, streamlined format. Access the complete contents anytime, anywhere at Expert Consult, and test your mastery of the latest knowledge with 500 online multiple-choice review questions.

Cancer Bioinformatics

Cancer Bioinformatics Book
Author : Ying Xu,Juan Cui,David Puett
Publisher : Springer
Release : 2014-08-30
ISBN : 1493913816
Language : En, Es, Fr & De

GET BOOK

Book Description :

This book provides a framework for computational researchers studying the basics of cancer through comparative analyses of omic data. It discusses how key cancer pathways can be analyzed and discovered to derive new insights into the disease and identifies diagnostic and prognostic markers for cancer. Chapters explain the basic cancer biology and how cancer develops, including the many potential survival routes. The examination of gene-expression patterns uncovers commonalities across multiple cancers and specific characteristics of individual cancer types. The authors also treat cancer as an evolving complex system, explore future case studies, and summarize the essential online data sources. Cancer Bioinformatics is designed for practitioners and researchers working in cancer research and bioinformatics. It is also suitable as a secondary textbook for advanced-level students studying computer science, biostatistics or biomedicine.

Hyaluronic Acid

Hyaluronic Acid Book
Author : V. N. Khabarov,P. Y. Boykov,M. A. Selyanin
Publisher : John Wiley & Sons
Release : 2014-12-22
ISBN : 1118695933
Language : En, Es, Fr & De

GET BOOK

Book Description :

Hyaluronic acid is an essential part of connective, epithelialand neural tissues, and contributes to cell proliferation andmigration. It is used as a stimulating agent for collagen synthesisand is a common ingredient in skin-care products, a multi-billiondollar industry, as it is believed to be a key factor in fightingthe aging process. Hyaluronic Acid: Production, Properties, Application inBiology and Medicine consists of six chapters discussing thevarious issues of hyaluronic acid research. In Chapter 1, ahistorical analysis recounts the discovery and milestones of theresearch leading to the practical applications of hyaluronan.Chapter 2 is dedicated to biological role of the hyaluronic acid innature, in particular in the human body. The chapter starts fromthe phylogenesis of hyaluronic acid, then describes hyaluronanfunctions in human ontogenesis and especially the role whichhyaluronan plays in extracellular matrix of the different tissues.Chapter 3 describes the methods to manufacture and purifyhyaluronic acid, including the analytical means for assessingquality of the finished product. Chapter 4 discusses the structureand rheological properties of hyaluronic acid considering effectson conformation and biological properties related to molecularweight. In Chapter 5, the physical and chemical methods formodifying the structure of hyaluronan are discussed includingcross-linking using bi-functional reagents, solid-phasemodification and effects of the combined action of high pressuresand shift deformation. The final chapter focuses on the productsderived from hyaluronic acid, including therapeutics composed ofmodified hyaluronan conjugated to vitamins, amino acids andoligo-peptides. The biological roles and medical applications ofthis polysaccharide have been extensively studied and this bookprovides a wealth of scientific data demonstrating the criticalrole of hyaluronic acid and its promise as a multifacetedbio-macromolecule. Approaching hyaluronic acid from multiple angles, this booklinks relationships between its biological functions, structure andphysical–chemical properties. It will be an invaluableresource to researchers, both industrial and academic, involved inall aspects of hyaluronan-based technologies.

Issues in Cancer Epidemiology and Research 2011 Edition

Issues in Cancer Epidemiology and Research  2011 Edition Book
Author : N.A
Publisher : ScholarlyEditions
Release : 2012-01-09
ISBN : 1464963525
Language : En, Es, Fr & De

GET BOOK

Book Description :

Issues in Cancer Epidemiology and Research / 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Cancer Epidemiology and Research. The editors have built Issues in Cancer Epidemiology and Research: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cancer Epidemiology and Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Cancer Epidemiology and Research: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Proceedings of the American Association for Cancer Research

Proceedings of the American Association for Cancer Research Book
Author : American Association for Cancer Research. Meeting,American Association for Cancer Research
Publisher :
Release : 2001
ISBN :
Language : En, Es, Fr & De

GET BOOK

Book Description :

Contains abstracts of the scientific proceedings of the 73rd- annual meetings of the American Association for Cancer Research (1982- ).

The Journal of Cell Biology

The Journal of Cell Biology Book
Author : N.A
Publisher :
Release : 2007
ISBN :
Language : En, Es, Fr & De

GET BOOK

Book Description :

No. 2, pt. 2 of November issue each year from v. 19 (1963)-47 (1970) and v. 55 (1972)- contain the Abstracts of papers presented at the Annual Meeting of the American Society for Cell Biology, 3d (1963)-10th (1970) and 12th (1972)-

Cancer Metastasis Molecular and Cellular Mechanisms and Clinical Intervention

Cancer Metastasis  Molecular and Cellular Mechanisms and Clinical Intervention Book
Author : Wen G. Jiang,R.E. Mansel
Publisher : Springer Science & Business Media
Release : 2000-10-31
ISBN : 0792363957
Language : En, Es, Fr & De

GET BOOK

Book Description :

This book covers the molecular and cellular aspects of cancer metastasis, and discusses the clinical aspect of micro- and macro-metastases, which result in the death of the majority of patients with cancer. The current edition attempts to examine the current status of the basic scientific and clinical research in the area, and is a very useful reference for clinicians, oncologists, and biologists. It is intended for undergraduates as well as postgraduates in the area of medicine, oncology, and cancer biology.

Hyaluronan

Hyaluronan Book
Author : J F Kennedy,Glyn O. Phillips,P A Williams,V C Hascall
Publisher : Elsevier
Release : 2002-10-04
ISBN : 1845693124
Language : En, Es, Fr & De

GET BOOK

Book Description :

Hyaluronan and its derivatives has developed very quickly in the last few years from a scientific novelty into an important new material for a diverse range of medical and biomaterial applications. This landmark conference focused on developments and applications in the use of hyaluronan in tissue repair and reconstruction, drug delivery systems, anti-cancer treatments and joint recovery and engineering. The entire range of hyaluronan progress is covered in depth by the more than 135 individual papers: Analytical chemistry Structural elucidation and basic chemistry Electron microscopy and atomic force microscopy Production, purification and characterisation Quality in production systems Chemical modification Derivatives and properties Cross-linking Free radical modification Physical characterisation Rheology Aggregation phenomena Interaction with water and solution properties Cell biology Control and regulation of HA synthases Cell surface chemistry HA cell receptors and cell signalling Interaction with proteins and other biological ligands Biophysical aspects Effects on pain receptors Neurobiology Role in organisation of extracellular matrix Role in development (embryogenesis): cell movement/migration Medical applications Uses in cartilage and wound repair Inflammation Wound regenerative healing Surgery and tissue engineering Viscosupplementation / osteoarthritis Viscoaugmentation and viscoprotection Anti-adhesion applications Brug delivery systems Binding onto tumour cells and metastases Outlines the proceedings of the landmark conference which focused on key developments and applications in the use of hyaluronan in tissue repair and reconstruction, among other uses The entire range of hyaluronan processes is dealt with in depth by more than 135 individual papers presented in two volumes Covers analytical chemistry, chemical modification, physical characterisation, cell biology and medical applications