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Human Reproductive Genetics

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Human Reproductive Genetics

Human Reproductive Genetics Book
Author : Juan A. Garcia-Velasco,Emre Seli
Publisher : Academic Press
Release : 2020-04-19
ISBN : 0128167491
Language : En, Es, Fr & De

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Book Description :

Human Reproductive Genetics: Emerging Technologies and Clinical Applications presents a great reference for clinicians and researchers in reproductive medicine. Part I includes a brief background of genetics and epigenetics, probability of disease, and the different techniques that are being used today for analysis and genetic counseling. Part II focuses on the analysis of the embryo, current controversies and future concepts. Part III comprises different clinical scenarios that clinicians frequently face in practice. The increasing amount of genetic tests available and the growing information that patients handle makes this section a relevant part of the fertility treatment discussion. Finally, Part IV concludes with the psychological aspects of genetic counseling and the role of counselor and bioethics in human reproduction. Provides an essential reference for clinicians involved in reproductive medicine Builds foundational knowledge on new genetic tests coming into the clinical scenario for physicians involved with patients Assembles critically evaluated chapters that cover basic concepts of genetics and epigenetics and the techniques involved, including preimplantation genetic testing, controversies, and more

Textbook of Human Reproductive Genetics

Textbook of Human Reproductive Genetics Book
Author : Karen Sermon,Stéphane Viville
Publisher : Cambridge University Press
Release : 2014-04-10
ISBN : 1107683580
Language : En, Es, Fr & De

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Book Description :

This book brings together genetics, reproductive biology and medicine for an integrative view of the emerging specialism of reproductive genetics.

Human Reproductive and Prenatal Genetics

Human Reproductive and Prenatal Genetics Book
Author : Peter C. K. Leung,Jie Qiao
Publisher : Academic Press
Release : 2018-08-28
ISBN : 0128135719
Language : En, Es, Fr & De

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Book Description :

Human Reproductive and Prenatal Genetics presents the latest material from a detailed molecular, cellular and translational perspective. Considering its timeliness and potential international impact, this all-inclusive and authoritative work is ideal for researchers, students, and clinicians worldwide. Currently, there are no comprehensive books covering the field of human reproductive and prenatal genetics. As such, this book aims to be among the largest and most useful references available. Features chapter contributions from leading international scientists and clinicians Provides in-depth coverage of key topics in human reproductive and prenatal genetics, including genetic controls, fertilization and implantation, in vitro culture of the human embryo for the study of post-implantation development, and more Identifies how researchers and clinicians can implement the latest genetic, epigenetic, and –omics based approaches

Reproductomics

Reproductomics Book
Author : José A. Horcajadas,Jaime Gosálvez
Publisher : Academic Press
Release : 2018-07-23
ISBN : 0128126760
Language : En, Es, Fr & De

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Book Description :

Recent advances in genomic and omics analysis have triggered a revolution affecting nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, and infertility treatment. Reproductomics: The –Omics Revolution and Its Impact on Human Reproductive Medicine demonstrates how various omics technologies are already aiding fertility specialists and clinicians in characterizing patients, counseling couples towards pregnancy success, informing embryo selection, and supporting many other positive outcomes. A diverse range of chapters from international experts examine the complex relationship between genomics, transcriptomics, proteomics, and metabolomics and their role in human reproduction, identifying molecular factors of clinical significance. With this book Editors Jaime Gosálvez and José A. Horcajadas have provided researchers and clinicians with a strong foundation for a new era of personalized reproductive medicine. Thoroughly discusses how genomics and other omics approaches aid clinicians in various areas of reproductive medicine Identifies specific genomic and molecular factors of translational value in treating infertility and analyzing patient data Features chapter contributions by leading international experts

Reproductive Genetics

Reproductive Genetics Book
Author : Sean Kehoe,Lyn Chitty,Tessa Homfray
Publisher : RCOG
Release : 2009-11
ISBN : 1906985162
Language : En, Es, Fr & De

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Book Description :

This book presents the findings of the RCOG Study Group findings on genetics underlying reproductive function.

The End of Sex and the Future of Human Reproduction

The End of Sex and the Future of Human Reproduction Book
Author : Henry T. Greely
Publisher : Harvard University Press
Release : 2016-05-30
ISBN : 0674728963
Language : En, Es, Fr & De

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Book Description :

Within twenty, maybe forty, years most people in developed countries will stop having sex for the purpose of reproduction. Instead, prospective parents will be told as much as they wish to know about the genetic makeup of dozens of embryos, and they will pick one or two for implantation, gestation, and birth. And it will be safe, lawful, and free. In this work of prophetic scholarship, Henry T. Greely explains the revolutionary biological technologies that make this future a seeming inevitability and sets out the deep ethical and legal challenges humanity faces as a result. “Readers looking for a more in-depth analysis of human genome modifications and reproductive technologies and their legal and ethical implications should strongly consider picking up Greely’s The End of Sex and the Future of Human Reproduction...[It has] the potential to empower readers to make informed decisions about the implementation of advancements in genetics technologies.” —Dov Greenbaum, Science “[Greely] provides an extraordinarily sophisticated analysis of the practical, political, legal, and ethical implications of the new world of human reproduction. His book is a model of highly informed, rigorous, thought-provoking speculation about an immensely important topic.” —Glenn C. Altschuler, Psychology Today

Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies

Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies Book
Author : Sorin Hostiuc
Publisher : Academic Press
Release : 2018-08-07
ISBN : 0128137657
Language : En, Es, Fr & De

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Book Description :

Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies offers thorough discussions on preconception carrier screening, genetic engineering and the use of CRISPR gene editing, mitochondrial gene replacement therapy, sex selection, predictive testing, secondary findings, embryo reduction and the moral status of the embryo, genetic enhancement, and the sharing of genetic data. Chapter contributions from leading bioethicists and clinicians encourage a global, holistic perspective on applied challenges and the moral questions relating the implementation of genetic reproductive technology. The book is an ideal resource for practitioners, regulators, lawmakers, clinical researchers, genetic counselors and graduate and medical students. As the Human Genome Project has triggered a technological revolution that has influenced nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, prenatal genetic testing, and gene therapy, this book presents a timely resource. Provides practical analysis of the ethical issues raised by cutting-edge techniques and recent advances in prenatal and reproductive genetics Contains contributions from leading bioethicists and clinicians who offer a global, holistic perspective on applied challenges and moral questions relating to genetic and genomic reproductive technology Discusses preconception carrier screening, genetic engineering and the use of CRISPR gene editing, mitochondrial gene replacement therapy, ethical issues, and more

Towards Reproductive Certainty Fertility and Genetics Beyond 1999 The Plenary Proceedings of the 11th World Congress

Towards Reproductive Certainty  Fertility and Genetics Beyond 1999  The Plenary Proceedings of the 11th World Congress Book
Author : R. Jansen,D. Mortimer
Publisher : CRC Press
Release : 1999-04-15
ISBN : 9781850700845
Language : En, Es, Fr & De

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Book Description :

This is a forward-looking clinical reference of definitive authority on today's headline controversies surrounding in vitro fertilization (IVF) and reproductive genetics. Written by leading experts from medicine, education, psychology, ethics, counseling, and other disciplines studying fertility and genetics, the book contains nearly 70 chapters in seven sections. The introductory section deals with biology, business, morality and society in IVF and reproductive genetics; other sections focus on IVF outcomes, personal ethics and business, biology of the egg, sperm and embryo, implantation, IVF and society, and such 21st century topics as space travel and human reproduction, the disappearing male,and the future of motherhood. Includes bibliographic references and index.

Genetic Dilemmas

Genetic Dilemmas Book
Author : Dena S. Davis
Publisher : Oxford University Press
Release : 2010
ISBN : 019537438X
Language : En, Es, Fr & De

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Book Description :

What limits the genetic choices parents make for their children? Is it okay to select the sex of our children, or for deaf parents to select deaf children? In this second edition of Genetic Dilemmas, Davis argues that parental reproductive autonomy should be limited by respect for the future autonomy of the children created by these measures. Praise for the first edition: "A thoughtful, timely and comprehensive look at genetics in the modern era by a recognized scholar of both their legal and humanistic implications. An excellent read!" -R. Alta Charo, Professor of Law and Medical Ethics, University of Wisconsin- Madison. "Dena Davis has been the most consistent and important voice insisting that we take seriously the concept of each child's right to an open future, and what respecting that right would mean for new technologies in genetics and reproduction. This engaging new book is the work of a thoughtful and humane scholar, and deserves a broad readership." -Thomas H. Murray, President of The Hastings Center "Dena Davis offers an engaging, informative and provocative argument in Genetic Dilemmas. Her primary accomplishment is to draw much-needed attention to the interests of the child in reproductive decision-making...she has succeeded admirably." -Mary Terrell White, Medical Humanities Review "People now face a dizzying array of choices about reproduction-from sex selection to cloning, from prenatal screening to genetic enhancement. In this engaging and path-breaking book, Dena Davis intelligently and compassionately explores the often-ignored impact of these choices on the children that are created and the society in which they will be raised." -Lori Andrews, Professor of Law, Chicago-Kent College of Law

Scientific and Medical Aspects of Human Reproductive Cloning

Scientific and Medical Aspects of Human Reproductive Cloning Book
Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Policy and Global Affairs,Committee on Science, Engineering, and Public Policy
Publisher : National Academies Press
Release : 2002-06-17
ISBN : 0309076374
Language : En, Es, Fr & De

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Book Description :

Human reproductive cloning is an assisted reproductive technology that would be carried out with the goal of creating a newborn genetically identical to another human being. It is currently the subject of much debate around the world, involving a variety of ethical, religious, societal, scientific, and medical issues. Scientific and Medical Aspects of Human Reproductive Cloning considers the scientific and medical sides of this issue, plus ethical issues that pertain to human-subjects research. Based on experience with reproductive cloning in animals, the report concludes that human reproductive cloning would be dangerous for the woman, fetus, and newborn, and is likely to fail. The study panel did not address the issue of whether human reproductive cloning, even if it were found to be medically safe, would beâ€"or would not beâ€"acceptable to individuals or society.

Human Reproductive Biology

Human Reproductive Biology Book
Author : Richard E. Jones,Kristin H. Lopez
Publisher : Elsevier
Release : 2006-05-15
ISBN : 9780080508368
Language : En, Es, Fr & De

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Book Description :

This acclaimed text has been fully revised and updated, now incorporating issues including aging of the reproductive system, and updates on the chapters on conception and Gamete Transport and Fertilization, and Pregnancy. Human Reproductive Biology, Third Edition emphasizes the biological and biomedical aspects of human reproduction, explains advances in reproductive science and discusses the choices and concerns of today. Generously illustrated in full color, the text provides current information about human reproductive anatomy and physiology. The ideal book for courses on human reproductive biology - includes chapter introductions, sidebars on related topics of interest, chapter summaries and suggestions for further reading. All material competely updated with the latest research results, methods, and topics now organized to facilitate logical presentation of topics New chapters on Reproductive Senescence, Conception: Gamete Transport, Fertilization, Pregnancy: Maternal Aspects and Pregnancy: Fetal Development Full color illustrations

Handbook of New Genetic Diagnostic Technologies in Reproductive Medicine

Handbook of New Genetic Diagnostic Technologies in Reproductive Medicine Book
Author : Carlos Simón,Carmen Rubio
Publisher : CRC Press
Release : 2017-12-14
ISBN : 1498763316
Language : En, Es, Fr & De

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Book Description :

Different genetic diagnostic and treatment options are used worldwide to improve routine IVF procedures for the benefit of patients. This handbook updates the new genetic diagnostic technologies that have been translated to practice aiming to improve outcomes in the clinic and have a healthy baby at home. Chapters cover the use of genetic technologies in a personalized manner to unravel the possible genetic risks for the couple wishing to conceive, in terms of sperm, the embryo, the endometrium, miscarriage, and finally the fetus.

The Reproductive System at a Glance

The Reproductive System at a Glance Book
Author : Linda J. Heffner,Danny J. Schust
Publisher : John Wiley & Sons
Release : 2014-02-12
ISBN : 1118606981
Language : En, Es, Fr & De

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Book Description :

The Reproductive System at a Glance is a comprehensive guide to normal reproductive biology and associated pathophysiology in both sexes. Concise, easy to read, and clearly structured, the double-page spreads progress from basic science to clinical abnormalities, and covers endocrine production and action, within one short volume. Chapters on disorders summarise epidemiology, pathophysiology, diagnosis and treatment. This new edition of The Reproductive System at a Glance: • Is fully revised and updated throughout to reflect recent developments in practice • Now features histological and pathological slides to complement the “at a glance” style explanatory illustrations • Now features radiologic studies to supplement the text in selected chapters • Contains more detailed coverage of maternal adaptations to pregnancy • Includes a companion website at www.ataglanceseries.com/reproduction featuring self-assessment multiple choice questions, bonus single answer questions and flashcards The Reproductive System at a Glance is an ideal guide for students studying both endocrine and reproductive subjects, and teaches the foundation concepts for the obstetrics and gynaecology rotation, helping health professionals and students achieve a broad and practical understanding of the topic.

Preimplantation Genetic Diagnosis

Preimplantation Genetic Diagnosis Book
Author : Joyce C. Harper,Joy D. A. Delhanty,Alan H. Handyside
Publisher : John Wiley & Sons
Release : 2003-01-17
ISBN : 0470851732
Language : En, Es, Fr & De

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Book Description :

Preimplantation Genetic Diagnosis (PGD) is the detection and screening of genetic abnormality in gametes prior to fertilisation and embryos fertilised in vitro prior to implantation. This exciting new text provides an introduction and overview of the principles of PGD. An exciting fusion of prenatal diagnosis (PD) with in vitro fertilisation (IVF), this book is will appeal to both the prenatal diagnosis community, of clinical geneticists and foetal medicine specialists within obstetrics and gynaecology, and the IVF community within reproductive medicine. It is also an essential introduction to PD, clinical genetics and IVF for non-specialists. A concise introduction to the field of PGD Detailed explanations of the techniques and procedures used The law and ethical implications of PGD Future uses of PGD

Exploring the Biological Contributions to Human Health

Exploring the Biological Contributions to Human Health Book
Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Understanding the Biology of Sex and Gender Differences
Publisher : National Academies Press
Release : 2001-07-02
ISBN : 9780309132978
Language : En, Es, Fr & De

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Book Description :

It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.

Heritable Human Genome Editing

Heritable Human Genome Editing Book
Author : The Royal Society,National Academy of Sciences,National Academy of Medicine,International Commission on the Clinical Use of Human Germline Genome Editing
Publisher : National Academies Press
Release : 2021-01-16
ISBN : 0309671132
Language : En, Es, Fr & De

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Book Description :

Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.

The Genetics of Male Infertility

The Genetics of Male Infertility Book
Author : Douglas T. Carrell
Publisher : Springer Science & Business Media
Release : 2007-11-08
ISBN : 1597451762
Language : En, Es, Fr & De

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Book Description :

In this book, twenty-one researchers and clinicians review the study of the genetics of male infertility, the tools available in the laboratory and clinic, the current state of knowledge, and the future of research and translation into clinical diagnostics and treatments. New tools discussed are discussed. This book therefore serves as a guide to evidence-based clinical applications, and a preview of future possibilities.

Human Population Genetics and Genomics

Human Population Genetics and Genomics Book
Author : Alan R. Templeton
Publisher : Academic Press
Release : 2018-11-08
ISBN : 0123860261
Language : En, Es, Fr & De

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Book Description :

Human Population Genetics and Genomics provides researchers/students with knowledge on population genetics and relevant statistical approaches to help them become more effective users of modern genetic, genomic and statistical tools. In-depth chapters offer thorough discussions of systems of mating, genetic drift, gene flow and subdivided populations, human population history, genotype and phenotype, detecting selection, units and targets of natural selection, adaptation to temporally and spatially variable environments, selection in age-structured populations, and genomics and society. As human genetics and genomics research often employs tools and approaches derived from population genetics, this book helps users understand the basic principles of these tools. In addition, studies often employ statistical approaches and analysis, so an understanding of basic statistical theory is also needed. Comprehensively explains the use of population genetics and genomics in medical applications and research Discusses the relevance of population genetics and genomics to major social issues, including race and the dangers of modern eugenics proposals Provides an overview of how population genetics and genomics helps us understand where we came from as a species and how we evolved into who we are now

Medical and Health Genomics

Medical and Health Genomics Book
Author : Dhavendra Kumar,Stylianos Antonarakis
Publisher : Academic Press
Release : 2016-06-04
ISBN : 0127999221
Language : En, Es, Fr & De

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Book Description :

Medical and Health Genomics provides concise and evidence-based technical and practical information on the applied and translational aspects of genome sciences and the technologies related to non-clinical medicine and public health. Coverage is based on evolving paradigms of genomic medicine—in particular, the relation to public and population health genomics now being rapidly incorporated in health management and administration, with further implications for clinical population and disease management. Provides extensive coverage of the emergent field of health genomics and its huge relevance to healthcare management Presents user-friendly language accompanied by explanatory diagrams, figures, and many references for further study Covers the applied, but non-clinical, sciences across disease discovery, genetic analysis, genetic screening, and prevention and management Details the impact of clinical genomics across a diverse array of public and community health issues, and within a variety of global healthcare systems

Assessing Genetic Risks

Assessing Genetic Risks Book
Author : Institute of Medicine,Committee on Assessing Genetic Risks
Publisher : National Academies Press
Release : 1994-01-01
ISBN : 0309047986
Language : En, Es, Fr & De

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Book Description :

Raising hopes for disease treatment and prevention, but also the specter of discrimination and "designer genes," genetic testing is potentially one of the most socially explosive developments of our time. This book presents a current assessment of this rapidly evolving field, offering principles for actions and research and recommendations on key issues in genetic testing and screening. Advantages of early genetic knowledge are balanced with issues associated with such knowledge: availability of treatment, privacy and discrimination, personal decisionmaking, public health objectives, cost, and more. Among the important issues covered: Quality control in genetic testing. Appropriate roles for public agencies, private health practitioners, and laboratories. Value-neutral education and counseling for persons considering testing. Use of test results in insurance, employment, and other settings.