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Human Prion Diseases

Human Prion Diseases Book
Author : Anonim
Publisher : Elsevier
Release : 2018-06-07
ISBN : 0444639535
Language : En, Es, Fr & De

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Book Description :

Human Prion Diseases, Volume 153 is designed to update the reader on the latest advances and clinical aspects of prion diseases. The book is organized into five sections, including the pathophysiology of prions and a description of animal and human diseases. This is followed by detailed reports on recent advances in diagnosis strategies for the development of novel anti-prion molecules and possible designs of clinical trials in such a rare disease. An introductory chapter gives an extensive historical background of prion research, with a final chapter highlighting recent progress, and more importantly, unsolved problems. Offers an authoritative overview of prion diseases in humans, detailing the pathogenesis of the disease, clinical investigations, and the diagnosis of both the genetic and acquired forms Provides clarity and context by presenting prion diseases in relation to other neurodegenerative diseases in humans Emphasizes the unique properties of prion diseases and consequent problems they can cause, both clinically and in public health terms

Prions in Humans and Animals

Prions in Humans and Animals Book
Author : Beat Hörnlimann,Detlev Riesner,Hans A. Kretzschmar
Publisher : Walter de Gruyter
Release : 2006-01-01
ISBN : 3110200171
Language : En, Es, Fr & De

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Book Description :

This comprehensive work, aimed at both students and researchers alike, systematically covers all aspects of prion diseases (transmissible spongiform encephalopathies), from their history, microbiology and pathology to their transmissibility and prevention. The book describes diseases such as Creutzfeldt-Jakob disease, kuru, mad cow disease (BSE), chronic wasting disease and scrapie, highlighting their biochemical, molecular biological, genetic, and clinical aspects. A renowned editorial team brought together 80 internationally respected authors for this translation and new edition of the successful German publication. The book includes chapters by, among many other notable scientists, William J. Hadlow, who discovered the relationship between the human and animal forms of prion diseases and Michael P. Alpers, with 45 years of experience in Papua New Guinea investigating the first known human epidemic form, kuru, transmitted by endocannibalism. Carefully edited with numerous illustrations, this work offers a systematic approach committed to a clear presentation of the current knowledge of prion diseases. It aims to inspire and stimulate interdisciplinary cooperation, innovative research ideas and effective prevention.

Prion Diseases

Prion Diseases Book
Author : Martin H. Groschup,Hans Kretzschmar
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 3709163080
Language : En, Es, Fr & De

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Book Description :

The overwhelming interest and the participation of more than 500 scientists from 26 countries made this symposium the largest meeting ever held in the field. In this book twenty-six invited speakers comprehensively present their data on the pathogenesis of prion diseases in humans and animals, on molecular mechanisms involved in the transmissibility across species barriers, on animal and in-vitro models currently available for the detection and quantification of infectivity and on the characterization of prion strains.

Prions and Diseases

Prions and Diseases Book
Author : Wen-Quan Zou,Pierluigi Gambetti
Publisher : Springer Science & Business Media
Release : 2012-11-08
ISBN : 1461453380
Language : En, Es, Fr & De

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Book Description :

Volume II features a variety of animal and human prion diseases, including the newly-identified atypical forms of bovine spongiform encephalopathy and scrapie in animals, and variably protease-sensitive prionopathy in humans, prions in the environment, Tau pathology in human prion disease, transmission of the disease by blood transfusion, mammalian and non-mammalian models, conventional and advanced diagnoses, prion-specific antibodies, as well as decontamination of prions and development of therapeutics of prion diseases, such as the application of immunomodulation. This volume provides up-to-date knowledge about the etiology, pathogenesis, classification, histopathological, and clinical aspects of the highly publicized animal and human prion diseases.

Cartes postales objets d art Compagnie des Indes fa ence

Cartes postales  objets d art  Compagnie des Indes  fa  ence    Book
Author : Anonim
Publisher : Unknown
Release : 1985
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Cartes postales objets d art Compagnie des Indes fa ence book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Prion Diseases New Insights for the Healthcare Professional 2012 Edition

Prion Diseases  New Insights for the Healthcare Professional  2012 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2012-12-10
ISBN : 1464980691
Language : En, Es, Fr & De

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Book Description :

Prion Diseases: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Prion Diseases in a compact format. The editors have built Prion Diseases: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Prion Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Prion Diseases: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Foodborne Infections and Intoxications

Foodborne Infections and Intoxications Book
Author : Alan J. Young,Jürgen A. Richt
Publisher : Elsevier Inc. Chapters
Release : 2013-03-06
ISBN : 0128073764
Language : En, Es, Fr & De

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Book Description :

In the last decade of the twentieth century, a new degenerative neurological disease in humans was linked to the consumption of bovine products derived from cattle suffering from a prion disease. Prions are a unique class of infectious agents, as they are resistant to most disinfection procedures that eliminate viral and bacterial contamination and may effectively cross species barriers. The prion agent consists of a conformationally distinct form of a normal cellular protein, which is capable of converting the normal protein into the diseased form. Studies on the pathogenesis of the bovine prion disease called bovine spongiform encephalopathy have demonstrated that certain cattle tissues represent a greater risk for infection of food products and feed materials, and removal of these tissues from bovine products destined for the human food chain has greatly reduced the risk of human infection. A current challenge is to further limit disease through development of live animal diagnostics capable of detecting disease prior to appearance of clinical signs.

CJD and Human Prion Disease

CJD and Human Prion Disease Book
Author : Anonim
Publisher : Unknown
Release : 2009
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

"Prion (pronounced "pree-on", or "pry-on") diseases are rare, fatal brain disorders, affecting humans and certain animals. Although they can develop from various causes, once developed these diseases can be transmitted (like infections) between individuals of the same or different species. Prion diseases began attracting public attention in the mid 1980s, due to BSE (Bovine Spongiform Encephalopathy), a prion disease of cattle. Although the origin of the disease remains unknown, the BSE epidemic was spread by contamination of animal feed with tissues from BSE-infected cattle. In humans, the best-known prion disease is CJD (Creutzfeldt-Jakob disease), which strikes about one to two in a million persons each year, resulting in around 35 new cases a year in Canada. ..."--Introduction.

Prion Diseases Advances in Research and Treatment 2012 Edition

Prion Diseases   Advances in Research and Treatment  2012 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2012-12-26
ISBN : 1481642901
Language : En, Es, Fr & De

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Book Description :

Prion Diseases—Advances in Research and Treatment: 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Prion Diseases in a compact format. The editors have built Prion Diseases—Advances in Research and Treatment: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Prion Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Prion Diseases—Advances in Research and Treatment: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Prions and Diseases

Prions and Diseases Book
Author : Wen-Quan Zou,Pierluigi Gambetti
Publisher : Springer Science & Business Media
Release : 2012-11-27
ISBN : 1461453054
Language : En, Es, Fr & De

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Book Description :

Volume I highlights the association of the cellular prion protein (PrPC) with copper and zinc, the potential roles of PrPC in Alzheimer’s disease and cancers, insoluble PrPC, PMCA, molecular and cellular mechanisms of PrPSc formation and clearance, possible co-factors involved in the conversion of PrPC into PrPSc, infectious and pathogenic forms of PrP, cell biology of prions, prion strains and their interference, as well as yeast prions and their inheritable and structural traits. This unique volume will take you through the fascinating chronicle of prions in mammals, yeast, and fungi.

What is Kuru A Deadly First Human Prion misfolded proteins Disease

What is Kuru  A Deadly First Human Prion  misfolded proteins Disease  Book
Author : Dr. Hakim. K. Saboowala
Publisher : Dr.Hakim Saboowala
Release : 2021-04-28
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

What is Kuru? A Deadly First Human Prion (misfolded proteins)Disease. Kuru is an incurable and fatal neurodegenerative disorder that was formerly common among the Fore people of Papua New Guinea. Kuru, the first human prion disease was transmitted to chimpanzees by D. Carleton Gajdusek (1923–2008). The discovery of kuru opened new vistas of human medicine and was pivotal in the subsequent transmission of Creutzfeldt–Jakob disease, as well as the relevance that bovine spongiform encephalopathy had for transmission to humans. The transmission of kuru was one of the greatest contributions to biomedical sciences of the 20th century. An attempt is made here to summarize the history of this seminal discovery, epidemiology, clinical picture, neuropathology, investigations, management, complications, prognosis and the descriptions of electron microscopy and confocal microscopy of kuru amyloid plaques along with several illustrations for better understanding of a quaint but interesting entity. …Dr. H. K. Saboowala. M.B.(Bom) .M.R.S.H.(London).

Prion Diseases and Copper Metabolism

Prion Diseases and Copper Metabolism Book
Author : D. Brown
Publisher : Elsevier
Release : 2002-10-01
ISBN : 0857099914
Language : En, Es, Fr & De

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Book Description :

International authorities here investigate research into the prion diseases which include Scrapie of sheep, BSE the "Mad Cow" disease, and CJD one of the human diseases. The role of metals in these diseases has become of great importance, linking it with some of the changes in Alzheimer's disease. The book focuses on metabolism of copper and manganese which are found in these diseases. It stems from proceedings of the international workshop at Christ's College, Cambridge University in 2001. After an introduction on the history of research into the diseases, there are discussions on the effects of copper on biochemical properties and prion proteins of brain cells, and newer techniques for their study. There is also a section on the relationship of Alzheimers disease to prion diseases. Focuses on metabolism of copper and manganese, which are found in Scrapie of sheep; BSE, the "Mad Cow" disease; and CJD, one of the human prion diseases Discusses the effects of copper on biochemical properties, prion proteins of brain cells and new techniques for their study Stems from the proceedings of the international workshop at Christ’s College, Cambridge University in 2001

Prion Diseases New Insights for the Healthcare Professional 2011 Edition

Prion Diseases  New Insights for the Healthcare Professional  2011 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2012-01-09
ISBN : 1464920184
Language : En, Es, Fr & De

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Book Description :

Prion Diseases: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Prion Diseases in a compact format. The editors have built Prion Diseases: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Prion Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Prion Diseases: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Prion Diseases of Humans and Animals

Prion Diseases of Humans and Animals Book
Author : Stanley B. Prusiner
Publisher : Ellis Horwood Limited
Release : 1992
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Prion Diseases of Humans and Animals book written by Stanley B. Prusiner, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Mad Cow Disease and Related Spongiform Encephalopathies

Mad Cow Disease and Related Spongiform Encephalopathies Book
Author : David A. Harris
Publisher : Springer Science & Business Media
Release : 2013-03-09
ISBN : 3662084414
Language : En, Es, Fr & De

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Book Description :

Bovine spongiform encephalopathy (BSE) has become the most publicly recognizable example of a group of fatal neurodegenerative diseases caused by proteinaceous infectious particles called prions. The contributors to this volume, all internationally recognized experts in their fields, provide an introduction to prion biology, followed by reviews of the latest information on BSE, vCJD, and chronic wasting disease, an animal prion disease that has recently emerged in North America.

Insights Into the Molecular Basis of Human Prion Diseases

Insights Into the Molecular Basis of Human Prion Diseases Book
Author : Dongmei Huang,Program in Microbiology and Immunology. Graduate School of Basic Medical Sciences,New York Medical College. Graduate School of Basic Medical Sciences
Publisher : Unknown
Release : 2002
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Insights Into the Molecular Basis of Human Prion Diseases book written by Dongmei Huang,Program in Microbiology and Immunology. Graduate School of Basic Medical Sciences,New York Medical College. Graduate School of Basic Medical Sciences, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Prions

Prions Book
Author : Holger F. Rabenau,Jindrich Cinatl,Hans Wilhelm Doerr
Publisher : Karger Medical and Scientific Publishers
Release : 2004
ISBN : 3805576560
Language : En, Es, Fr & De

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Book Description :

This second, completely revised and extended edition of Prions: A Challenge for Science, Medicine and the Public Health System is a comprehensive, up-to-date review of prions and prion-associated diseases. Leading scientists discuss the structure, molecular biology and origin of prions as well as strain variations and species barriers. Human prion diseases, prion inactivation and risks to public health are considered in detail. The new edition provides an update on basic findings of the last three years since publication of the previous edition and emphasizes practical aspects of fighting human and animal prion diseases. In addition, chapters on regulatory aspects of BSE and CJD as well as on veterinary measures have been included. A valuable single source of information on what is currently known about prions, this book will be of interest to any scientist or clinician who wants to keep up with the latest developments in this fast-moving field.

Studies on the Aetiology of Human Prion Diseases

Studies on the Aetiology of Human Prion Diseases Book
Author : Kathleen Claire Louise Sidle
Publisher : Unknown
Release : 1995
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Studies on the Aetiology of Human Prion Diseases book written by Kathleen Claire Louise Sidle, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Pathological Protein

The Pathological Protein Book
Author : Philip Yam
Publisher : Springer Science & Business Media
Release : 2007-05-08
ISBN : 038721755X
Language : En, Es, Fr & De

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Book Description :

Prions are an entirely new class of pathogens, and scientists are just beginning to understand them. Although they have plagued humans and animals for 3 centuries, only in the last 2 decades have researchers linked them to diseases like Mad Cow. This book tells the strange story of their discovery, and the medical controversies that swirl around them. The author, Philip Yam, is a well-respected and connected journalist who is now an editor at Scientific American.

Prion Protein

Prion Protein Book
Author : Anonim
Publisher : Academic Press
Release : 2017-08-22
ISBN : 0128112271
Language : En, Es, Fr & De

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Book Description :

Prion Protein, Volume 150, the latest volume in the Progress in Molecular Biology and Translational Science series, focuses on Prion Protein, a protein that is considered to be the archetype of intrinsically disordered proteins. This updated volume includes comprehensive sections on a variety of timely topics, including Functions of Prion Protein, Copper and Prion protein, Cell Biology of Prion Protein, Structural Studies of Prion Proteins, Molecular Simulations on Wild Type and Mutant Prion Proteins, Genetics of Prion Protein, The Prion Concept and Synthetic Prions, and Transgenic Mouse Models. As neurodegenerative diseases represent a health issue that is receiving increasing attention from the scientific community due to their social and economic impact, this series is an ideal resource for the latest research in molecular biology and translational science. Presents the latest volume in the Progress in Molecular Biology and Translational Science series Accessible to students and researcher alike Written by leading authorities in the field of prion protein