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Human Prion Diseases

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Human Prion Diseases

Human Prion Diseases Book
Author : Anonim
Publisher : Elsevier
Release : 2018-06-07
ISBN : 0444639535
Language : En, Es, Fr & De

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Book Description :

Human Prion Diseases, Volume 153 is designed to update the reader on the latest advances and clinical aspects of prion diseases. The book is organized into five sections, including the pathophysiology of prions and a description of animal and human diseases. This is followed by detailed reports on recent advances in diagnosis strategies for the development of novel anti-prion molecules and possible designs of clinical trials in such a rare disease. An introductory chapter gives an extensive historical background of prion research, with a final chapter highlighting recent progress, and more importantly, unsolved problems. Offers an authoritative overview of prion diseases in humans, detailing the pathogenesis of the disease, clinical investigations, and the diagnosis of both the genetic and acquired forms Provides clarity and context by presenting prion diseases in relation to other neurodegenerative diseases in humans Emphasizes the unique properties of prion diseases and consequent problems they can cause, both clinically and in public health terms

Prions in Humans and Animals

Prions in Humans and Animals Book
Author : Beat Hörnlimann,Detlev Riesner,Hans A. Kretzschmar
Publisher : Walter de Gruyter
Release : 2006-01-01
ISBN : 3110200171
Language : En, Es, Fr & De

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Book Description :

This comprehensive work, aimed at both students and researchers alike, systematically covers all aspects of prion diseases (transmissible spongiform encephalopathies), from their history, microbiology and pathology to their transmissibility and prevention. The book describes diseases such as Creutzfeldt-Jakob disease, kuru, mad cow disease (BSE), chronic wasting disease and scrapie, highlighting their biochemical, molecular biological, genetic, and clinical aspects. A renowned editorial team brought together 80 internationally respected authors for this translation and new edition of the successful German publication. The book includes chapters by, among many other notable scientists, William J. Hadlow, who discovered the relationship between the human and animal forms of prion diseases and Michael P. Alpers, with 45 years of experience in Papua New Guinea investigating the first known human epidemic form, kuru, transmitted by endocannibalism. Carefully edited with numerous illustrations, this work offers a systematic approach committed to a clear presentation of the current knowledge of prion diseases. It aims to inspire and stimulate interdisciplinary cooperation, innovative research ideas and effective prevention.

Prions and Diseases

Prions and Diseases Book
Author : Wen-Quan Zou,Pierluigi Gambetti
Publisher : Springer Science & Business Media
Release : 2012-11-08
ISBN : 1461453380
Language : En, Es, Fr & De

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Book Description :

Volume II features a variety of animal and human prion diseases, including the newly-identified atypical forms of bovine spongiform encephalopathy and scrapie in animals, and variably protease-sensitive prionopathy in humans, prions in the environment, Tau pathology in human prion disease, transmission of the disease by blood transfusion, mammalian and non-mammalian models, conventional and advanced diagnoses, prion-specific antibodies, as well as decontamination of prions and development of therapeutics of prion diseases, such as the application of immunomodulation. This volume provides up-to-date knowledge about the etiology, pathogenesis, classification, histopathological, and clinical aspects of the highly publicized animal and human prion diseases.

Fatal Protein

Fatal Protein Book
Author : Rosalind M. Ridley,Harry F. Baker
Publisher : Oxford University Press, USA
Release : 1998
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This book presents a clear and authoritative account of the prion diseases for the non-specialist. It deals with the history of scrapie in sheep, the spread of kuru through cannibalism in Papua New Guinea, BSE, which has killed 170,000 cattle in the UK, and the question of whether the newvariant form of Creutzfeld-Jakob disease (CJD) results from eating BSE-infected meat. All aspects of the diseases are covered, including genetics, clinical aspects, laboratory research, epidemiology, and field studies. Accessibly written by authors who are leading researchers in the field, it is thefirst book to provide a scientifically accurate yet readable account of these topical diseases.

Prions and Prion Diseases

Prions and Prion Diseases Book
Author : Jean-Michel Verdier
Publisher : Nova Biomedical
Release : 2012
ISBN : 9781621000273
Language : En, Es, Fr & De

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Book Description :

Table of Contents - Preface; I. Neuropathology of human prion diseases; II. The nature of the infectious agents - PrP models of resistant species to prion diseases (dog, rabbit and horses); III. Inducing transmissible prion diseases with recombinant fibrils - a new concept on genesis and evolution of infectious prions; IV. Synthetic prions; V. Recent development in cell biology - role of glycosylation in prion diseases; VI. Transmissibility of prion diseases in rodent models - atypical strains; VII. Pre-Mortem diagnostic screening for transmissible spongiform encephalopathies by proteomic approaches; VIII. Added value of biochemical tools for the diagnosis of human prion disease; IX. Anti-prion strategies for in vivo gene therapy assays; Index.

Prion Diseases

Prion Diseases Book
Author : John Collinge (MD.),Mark S. Palmer,Mark Palmer
Publisher : Oxford University Press, USA
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The number of neurological conditions associated with the mutant "prion" protein continues to grow. The list includes BSE and scrapie, which affect cattle and sheep respectively, and Creutzfeldt-Jacob Disease, which affects humans. This is an area of intense interest to neuroscientists,veterinary scientists, and clinicians. It has also attracted significant media attention because of the potential risks to humans. This book brings together leading researchers in the field to provide the most up-to-date and authoritative summary available of the field.Contents include human and animal prion diseases; pathology and cell biology of prion diseases; and prion protein structure.

The Development of Imaging Biomarkers for the Diagnosis of Human Prion Disease

The Development of Imaging Biomarkers for the Diagnosis of Human Prion Disease Book
Author : Marie-Claire Anne Porter
Publisher : Unknown
Release : 2020
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Development of Imaging Biomarkers for the Diagnosis of Human Prion Disease book written by Marie-Claire Anne Porter, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Prions

Prions Book
Author : Akikazu Sakudo
Publisher : Caister Academic Press
Release : 2019-04-15
ISBN : 1910190969
Language : En, Es, Fr & De

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Book Description :

Prion diseases or transmissible spongiform encephalopathies (TSEs) are fatal neurological diseases that include, for example, Creutzfeldt-Jakob Disease (CJD) in humans and bovine spongiform encephalopathy (BSE) in cattle. Since the publication of the first edition of this book in 2013 significant progress has been made in advanced prion research creating a need for this timely revised and updated edition. The book opens with an introductory chapter that provides an overview. This is followed by four chapters (chapters 2-5) dealing with fundamental aspects of prion biology, including functions of the cellular isoform of prion protein (PrPC) and molecular mechanisms of prion diseases. The next two chapters (chapters 6-7) focus on clinical aspects of human prion diseases and current approaches for effective inactivation methods. The last part of the book (chapters 8-9) summarizes animal prion diseases, including BSE, scrapie and chronic wasting disease (CWD). In the final chapter, Professor Onodera discusses the likely future direction of research. This book is essential reading for everyone working with prions from the PhD student to the experienced scientist, in academia, the pharmaceutical or biotechnology industries and for those working in clinical environments.

Emerging Infectious Diseases

Emerging Infectious Diseases Book
Author : Anonim
Publisher : Unknown
Release : 2014
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Emerging Infectious Diseases book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Cumulated Index Medicus

Cumulated Index Medicus Book
Author : Anonim
Publisher : Unknown
Release : 1994
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Cumulated Index Medicus book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Biosafety in Microbiological and Biomedical Laboratories

Biosafety in Microbiological and Biomedical Laboratories Book
Author : Anonim
Publisher : Unknown
Release : 1999
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Biosafety in Microbiological and Biomedical Laboratories book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Oxford Textbook of Neurologic and Neuropsychiatric Epidemiology

Oxford Textbook of Neurologic and Neuropsychiatric Epidemiology Book
Author : Carol Brayne,Professor of Public Health Medicine and Director of the Cambridge University Department of Public Health Carol Brayne,Director National Institute for Stroke and Applied Neuroscience (Nisan) Valery Feigin,Valery Feigin,Lenore Launer,Giancarlo Logroscino
Publisher : Oxford University Press, USA
Release : 2020-11-02
ISBN : 019874949X
Language : En, Es, Fr & De

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Book Description :

The Oxford Textbook of Neurologic and Neuropsychiatric Epidemiology focuses on the overlaps between neuro-epidemiological disorders. Harmonising cohort studies to determine causes related to rarer disorders, this key work is an invaluable reference to current neuro-epidemiological methods.

Towards a Structural Understanding of Progression and Transmission of Prion Diseases

Towards a Structural Understanding of Progression and Transmission of Prion Diseases Book
Author : Marcin Izydor Apostol
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Towards a Structural Understanding of Progression and Transmission of Prion Diseases book written by Marcin Izydor Apostol, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Prion Diseases of Mammals and Yeast

Prion Diseases of Mammals and Yeast Book
Author : Reed B. Wickner
Publisher : R G Landes Company
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Prion Diseases of Mammals and Yeast book written by Reed B. Wickner, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Prion Diseases

Prion Diseases Book
Author : Stanley B. Prusiner
Publisher : Unknown
Release : 2017
ISBN : 9781621822837
Language : En, Es, Fr & De

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Book Description :

"Infectious proteins called prions are responsible for the devastating transmissible spongioform encephalopathy Creutzfeldt-Jakob disease. Prions are misfolded versions of proteins that replicate by converting their normal cellular counterparts into new prions and may play an important role in numerous other conditions, including Alzheimer and Parkinson's disease. Highlights include: Structural biology of PrP prions - Genetics of APP in Alzheimer's disease - Challenges of therapeutics for prion diseases and blood-brain barrier "--

Theoretical and Computational Study of Prion Diseases

Theoretical and Computational Study of Prion Diseases Book
Author : Jianping Pan
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Theoretical and Computational Study of Prion Diseases book written by Jianping Pan, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Human Diseases and Conditions

Human Diseases and Conditions Book
Author : Miranda Herbert Ferrara
Publisher : Charles Scribner's Sons
Release : 2010
ISBN : 9780684312415
Language : En, Es, Fr & De

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Book Description :

This volume presents alphabetically arranged articles dealing with all kinds of diseases and disorders, from jaundice to rubella.

Creutzfeldt Jakob Disease

Creutzfeldt Jakob Disease Book
Author : Mic J. Stones
Publisher : Nova Publishers
Release : 2006
ISBN : 9781600213458
Language : En, Es, Fr & De

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Book Description :

Creutzfeldt-Jakob Disease is a very rare and incurable degenerative neurological disorder that is ultimately fatal. It is the most common of the transmissible spongiform encephalopathies. Transmissible spongiform encephalopathy diseases (also known as prion diseases) are caused by a unique type of infectious agent called prions, an abnormally structured form of a protein found in the brain. Other prion diseases include Gerstmann-Sträussler-Scheinker syndrome (GSS), fatal familial insomnia (FFI) and kuru in humans, as well as bovine spongiform encephalopathy (BSE) and scrapie in animals. This book presents the latest research in this field.

Encyclopedia of Molecular Biology and Molecular Medicine Plasmids to Synthetic Peptide and Nonpeptide Combinatorial Libraries

Encyclopedia of Molecular Biology and Molecular Medicine  Plasmids to Synthetic Peptide and Nonpeptide Combinatorial Libraries Book
Author : Robert A. Meyers
Publisher : Wiley-Blackwell
Release : 1996-12-12
ISBN : 9783527284757
Language : En, Es, Fr & De

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Book Description :

This six volume Encyclopedia is the most comprehensive, detailed treatment of molecular biology and molecular medicine available today! The Encyclopedia provides a single-source library of molecular genetics and the molecular basis of life, with a focus on molecular medicine. Genetic screening, gene therapy, structural biology, and the technology and findings of the Human Genome Project are discussed in detail. The articles that comprise the set are designed as self-contained treatments. Each of the nearly 300 articles begins with an outline and a key word section which includes definitions. These features assist the scientist or student who is unfamiliar with a specific subject area. A glossary of basic terms completes each volume and defines the most commonly used terms in molecular biology. Together with the introductory illustrations found in each volume, these definitions enable readers to understand articles without referring to a dictionary, textbook, or other reference.

International Meeting on Transmissible Spongiform Encephalopathies Impact on Animal and Human Health

International Meeting on Transmissible Spongiform Encephalopathies   Impact on Animal and Human Health Book
Author : International Meeting on Transmissible Spongiform Encephalopathies - Impact on Animal and Human Health
Publisher : Unknown
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download International Meeting on Transmissible Spongiform Encephalopathies Impact on Animal and Human Health book written by International Meeting on Transmissible Spongiform Encephalopathies - Impact on Animal and Human Health, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.