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Human Population Genetics And Genomics

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Human Population Genetics and Genomics

Human Population Genetics and Genomics Book
Author : Alan R. Templeton
Publisher : Academic Press
Release : 2018-11-08
ISBN : 0123860261
Language : En, Es, Fr & De

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Book Description :

Human Population Genetics and Genomics provides researchers/students with knowledge on population genetics and relevant statistical approaches to help them become more effective users of modern genetic, genomic and statistical tools. In-depth chapters offer thorough discussions of systems of mating, genetic drift, gene flow and subdivided populations, human population history, genotype and phenotype, detecting selection, units and targets of natural selection, adaptation to temporally and spatially variable environments, selection in age-structured populations, and genomics and society. As human genetics and genomics research often employs tools and approaches derived from population genetics, this book helps users understand the basic principles of these tools. In addition, studies often employ statistical approaches and analysis, so an understanding of basic statistical theory is also needed. Comprehensively explains the use of population genetics and genomics in medical applications and research Discusses the relevance of population genetics and genomics to major social issues, including race and the dangers of modern eugenics proposals Provides an overview of how population genetics and genomics helps us understand where we came from as a species and how we evolved into who we are now

A Primer of Population Genetics and Genomics

A Primer of Population Genetics and Genomics Book
Author : Daniel L. Hartl
Publisher : Oxford University Press, USA
Release : 2020-06-25
ISBN : 0198862296
Language : En, Es, Fr & De

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Book Description :

This accessible primer has been completely revised and updated to provide a concise but comprehensive introduction to the basic concepts of population genetics and genomics.

Genomic Diversity

Genomic Diversity Book
Author : Surinder Singh Papiha,Ranjan Deka,Ranajit Chakraborty
Publisher : Springer Science & Business Media
Release : 1999-10-31
ISBN : 9780306462955
Language : En, Es, Fr & De

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Book Description :

Proceedings of the Symposium on Molecular Anthropology in the 21st Century, held during the 14th International Congress of the Association of Anthropological and Ethnological Sciences, 26 July to 1 August, 1998, in Williamsburg, Virginia, USA

The Genetics of Human Populations

The Genetics of Human Populations Book
Author : Luigi Luca Cavalli-Sforza,Walter Fred Bodmer
Publisher : Courier Corporation
Release : 1999
ISBN : 0486406938
Language : En, Es, Fr & De

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Book Description :

Comprehensive, advanced treatment of nature and source of inherited characteristics, with treatment of mathematical techniques. Mendelian populations, mutations, polymorphisms, genetic demography, much more. Emphasizes interpretation of data in relation to theoretical models.

Genetics

Genetics Book
Author : Daniel L. Hartl,Elizabeth W. Jones
Publisher : Jones & Bartlett Learning
Release : 2005
ISBN : 9780763715113
Language : En, Es, Fr & De

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Book Description :

Biological Sciences

Forward Time Population Genetics Simulations

Forward Time Population Genetics Simulations Book
Author : Bo Peng,Marek Kimmel,Christopher I. Amos
Publisher : John Wiley & Sons
Release : 2012-02-14
ISBN : 0470503483
Language : En, Es, Fr & De

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Book Description :

The rapid increase of the power of personal computers has led to the use of serious simulation programs such as easy POP in genetic studies. This book summarizes recent advances in forward-time simulation methods and demonstrates their applications in population genetics and genetic epidemiology. The authors introduce commonly used forward-time population genetics simulation methods, including some new methods, and introduce a forward-time population genetics simulation environment, simuPOP, as a powerful and flexible tool to implement these simulations. Researchers and students in population and statistical genetics will find this book useful.

Human Genetics and Genomics

Human Genetics and Genomics Book
Author : Bruce R. Korf,Mira B. Irons
Publisher : John Wiley & Sons
Release : 2012-11-19
ISBN : 1118537661
Language : En, Es, Fr & De

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Book Description :

This fourth edition of the best-selling textbook, Human Genetics and Genomics, clearly explains the key principles needed by medical and health sciences students, from the basis of molecular genetics, to clinical applications used in the treatment of both rare and common conditions. A newly expanded Part 1, Basic Principles of Human Genetics, focuses on introducing the reader to key concepts such as Mendelian principles, DNA replication and gene expression. Part 2, Genetics and Genomics in Medical Practice, uses case scenarios to help you engage with current genetic practice. Now featuring full-color diagrams, Human Genetics and Genomics has been rigorously updated to reflect today’s genetics teaching, and includes updated discussion of genetic risk assessment, “single gene” disorders and therapeutics. Key learning features include: Clinical snapshots to help relate science to practice ‘Hot topics’ boxes that focus on the latest developments in testing, assessment and treatment ‘Ethical issues’ boxes to prompt further thought and discussion on the implications of genetic developments ‘Sources of information’ boxes to assist with the practicalities of clinical research and information provision Self-assessment review questions in each chapter Accompanied by the Wiley E-Text digital edition (included in the price of the book), Human Genetics and Genomics is also fully supported by a suite of online resources at www.korfgenetics.com, including: Factsheets on 100 genetic disorders, ideal for study and exam preparation Interactive Multiple Choice Questions (MCQs) with feedback on all answers Links to online resources for further study Figures from the book available as PowerPoint slides, ideal for teaching purposes The perfect companion to the genetics component of both problem-based learning and integrated medical courses, Human Genetics and Genomics presents the ideal balance between the bio-molecular basis of genetics and clinical cases, and provides an invaluable overview for anyone wishing to engage with this fast-moving discipline.

Human Genes and Genomes

Human Genes and Genomes Book
Author : Leon E. Rosenberg,Diane Drobnis Rosenberg
Publisher : Academic Press
Release : 2012-05-21
ISBN : 0123852137
Language : En, Es, Fr & De

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Book Description :

In the nearly 60 years since Watson and Crick proposed the double helical structure of DNA, the molecule of heredity, waves of discoveries have made genetics the most thrilling field in the sciences. The study of genes and genomics today explores all aspects of the life with relevance in the lab, in the doctor’s office, in the courtroom and even in social relationships. In this helpful guidebook, one of the most respected and accomplished human geneticists of our time communicates the importance of genes and genomics studies in all aspects of life. With the use of core concepts and the integration of extensive references, this book provides students and professionals alike with the most in-depth view of the current state of the science and its relevance across disciplines. Bridges the gap between basic human genetic understanding and one of the most promising avenues for advances in the diagnosis, prevention and treatment of human disease. Includes the latest information on diagnostic testing, population screening, predicting disease susceptibility, pharmacogenomics and more Explores ethical, legal, regulatory and economic aspects of genomics in medicine. Integrates historical (classical) genetics approach with the latest discoveries in structural and functional genomics

Human Evolutionary Genetics Second Edition

Human Evolutionary Genetics  Second Edition Book
Author : Mark Jobling,Edward Hollox,Matthew Hurles,Toomas Kivisild,Chris Tyler-Smith
Publisher : Garland Science
Release : 2013-06-23
ISBN : 131795226X
Language : En, Es, Fr & De

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Book Description :

Now in full-color, the Second Edition of Human Evolutionary Genetics has been completely revised to cover the rapid advances in the field since publication of the highly regarded First Edition. Written for upper-level undergraduate and graduate students, it is the only textbook to integrate genetic, archaeological, and linguistic perspectives on human evolution, and to offer a genomic perspective, reflecting the shift from studies of specific regions of the genome towards comprehensive genomewide analyses of human genetic diversity. Human Evolutionary Genetics is suitable for courses in Genetics, Evolution, and Anthropology. Those readers with a background in anthropology will find that the streamlined genetic analysis material contained in the Second Edition is more accessible. The new edition also integrates new technologies (including next-generation sequencing and genome-wide SNP typing) and new data analysis methods, including recent data on ancient genomes and their impact on our understanding of human evolution. The book also examines the subject of personal genomics and its implications.

Population Genomics

Population Genomics Book
Author : Om P. Rajora
Publisher : Springer
Release : 2019-01-07
ISBN : 3030045897
Language : En, Es, Fr & De

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Book Description :

Population genomics has revolutionized various disciplines of biology including population, evolutionary, ecological and conservation genetics, plant and animal breeding, human health, medicine and pharmacology by allowing to address novel and long-standing questions with unprecedented power and accuracy. It employs large-scale or genome-wide genetic information and bioinformatics to address various fundamental and applied aspects in biology and related disciplines, and provides a comprehensive genome-wide perspective and new insights that were not possible before. These advances have become possible due to the development of new and low-cost sequencing and genotyping technologies and novel statistical approaches and software, bioinformatics tools, and models. Population genomics is tremendously advancing our understanding the roles of evolutionary processes, such as mutation, genetic drift, gene flow, and natural selection, in shaping up genetic variation at individual loci and across the genome and populations; improving the assessment of population genetic parameters or processes such as adaptive evolution, effective population size, gene flow, admixture, inbreeding and outbreeding depression, demography, and biogeography; resolving evolutionary histories and phylogenetic relationships of extant, ancient and extinct species; understanding the genomic basis of fitness, adaptation, speciation, complex ecological and economically important traits, and disease and insect resistance; facilitating forensics, genetic medicine and pharmacology; delineating conservation genetic units; and understanding the genetic effects of resource management practices, and assisting conservation and sustainable management of genetic resources. This Population Genomics book discusses the concepts, approaches, applications and promises of population genomics in addressing most of the above fundamental and applied crucial aspects in a variety of organisms from microorganisms to humans. The book provides insights into a range of emerging population genomics topics including population epigenomics, landscape genomics, seascape genomics, paleogenomics, ecological and evolutionary genomics, biogeography, demography, speciation, admixture, colonization and invasion, genomic selection, and plant and animal domestication. This book fills a vacuum in the field and is expected to become a primary reference in Population Genomics world-wide.

Population Genetics and Microevolutionary Theory

Population Genetics and Microevolutionary Theory Book
Author : Alan R. Templeton
Publisher : John Wiley & Sons
Release : 2006-09-29
ISBN : 0470047216
Language : En, Es, Fr & De

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Book Description :

The advances made possible by the development of molecular techniques have in recent years revolutionized quantitative genetics and its relevance for population genetics. Population Genetics and Microevolutionary Theory takes a modern approach to population genetics, incorporating modern molecular biology, species-level evolutionary biology, and a thorough acknowledgment of quantitative genetics as the theoretical basis for population genetics. Logically organized into three main sections on population structure and history, genotype-phenotype interactions, and selection/adaptation Extensive use of real examples to illustrate concepts Written in a clear and accessible manner and devoid of complex mathematical equations Includes the author's introduction to background material as well as a conclusion for a handy overview of the field and its modern applications Each chapter ends with a set of review questions and answers Offers helpful general references and Internet links

Human Population Genomics

Human Population Genomics Book
Author : Kirk E. Lohmueller
Publisher : Springer Nature
Release : 2021-04-19
ISBN : 3030616460
Language : En, Es, Fr & De

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Book Description :

Download Human Population Genomics book written by Kirk E. Lohmueller, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Heredity Under the Microscope

Heredity Under the Microscope Book
Author : Soraya de Chadarevian
Publisher : Unknown
Release : 2020
ISBN : 022668511X
Language : En, Es, Fr & De

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Book Description :

"By focusing on the chromosome in the quest to study and harness human heredity, Heredity under the Microscope offers a new history of postwar genetics. Today chromosomes are understood as macromolecular assemblies and analyzed with an array of molecular techniques. Yet throughout much of the twentieth century, researchers studied chromosomes by looking down the microscope at darkly stained bodies in the cell. In the 1950s, improved chromosome preparations offered a direct glimpse of the complete genome of an individual, opening up seemingly endless possibilities of observation and interventions. Much of the fascination with chromosomes and their persuasive power was based on the visual evidence the chromosome preparations provided, but critics countered that looking at pictures was not enough: we needed to understand the mechanisms. De Chadarevian argues that the often-bewildering variety of observations made by chromosome researchers were as central to the making of human heredity as the search for fundamental mechanisms pursued through the study of model organisms"--

The Human Genome

The Human Genome Book
Author : Julia E. Richards,R. Scott Hawley
Publisher : Academic Press
Release : 2010-12-12
ISBN : 9780080918655
Language : En, Es, Fr & De

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Book Description :

Significant advances in our knowledge of genetics were made during the twentieth century but in the most recent decades, genetic research has dramatically increased its impact throughout society. Genetic issues are now playing a large role in health and public policy, and new knowledge in this field will continue to have significant implications for individuals and society. Written for the non-majors human genetics course, Human Genetics, 3E will increase the genetics knowledge of students who are learning about human genetics for the first time. This thorough revision of the best-selling Human Genome,2E includes entirely new chapters on forensics, stem cell biology, bioinformatics, and societal/ethical issues associated with the field. New special features boxes make connections between human genetics and human health and disease. Carefully crafted pedagogy includes chapter-opening case studies that set the stage for each chapter; concept statements interspersed throughout the chapter that keep first-time students focused on key concepts; and end-of-chapter questions and critical thinking activities. This new edition will contribute to creating a genetically literate student population that understands basic biological research, understands elements of the personal and health implications of genetics, and participates effectively in public policy issues involving genetic information . Includes topical material on forensics, disease studies, and the human genome project to engage non-specialist students Full, 4-color illustration program enhances and reinforces key concepts and themes Uniform organization of chapters includes interest boxes that focus on human health and disease, chapter-opening case studies, and concept statements to engage non-specialist readers

Vogel and Motulsky s Human Genetics

Vogel and Motulsky s Human Genetics Book
Author : Michael Speicher,Stylianos E. Antonarakis,Arno G. Motulsky
Publisher : Springer Science & Business Media
Release : 2009-11-26
ISBN : 3540376542
Language : En, Es, Fr & De

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Book Description :

The fourth edition of this classical reference book can once again be relied upon to present a cohesive and up-to-date exposition of all aspects of human and medical genetics. Human genetics has become one of the main basic sciences in medicine, and molecular genetics is increasingly becoming a major part of this field. This new edition integrates a wealth of new information - mainly describing the influence of the "molecular revolution" - including the principles of epigenetic processes which together create the phenotype of a human being. Other revisions are an improved layout, sub-division into a larger number of chapters, as well as two-colour print throughout for ease of reference, and many of the figures are now in full colour. For graduates and those already working in medical genetics.

Human Genome News

Human Genome News Book
Author : Anonim
Publisher : Unknown
Release : 1989
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Human Genome News book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The History and Geography of Human Genes

The History and Geography of Human Genes Book
Author : Luigi Luca Cavalli-Sforza,Paolo Menozzi,Alberto Piazza
Publisher : Princeton University Press
Release : 2018-06-05
ISBN : 0691187266
Language : En, Es, Fr & De

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Book Description :

Hailed as a breakthrough in the understanding of human evolution, The History and Geography of Human Genes offers the first full-scale reconstruction of where human populations originated and the paths by which they spread throughout the world. By mapping the worldwide geographic distribution of genes for over 110 traits in over 1800 primarily aboriginal populations, the authors charted migrations and devised a clock by which to date evolutionary history. This monumental work is now available in a more affordable paperback edition without the myriad illustrations and maps, but containing the full text and partial appendices of the authors' pathbreaking endeavor.

Essential Genetics

Essential Genetics Book
Author : Daniel Hartl
Publisher : Jones & Bartlett Learning
Release : 2011
ISBN : 0763773646
Language : En, Es, Fr & De

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Book Description :

Updated to reflect the latest discoveries in the field, the Fifth Edition of Hartl's classic text provides an accessible, student-friendly introduction to contemporary genetics. Designed for the shorter, less comprehensive introductory course, Essential Genetics: A Genomic Perspective, Fifth Edition includes carefully chosen topics that provide a solid foundation to the basic understanding of gene mutation, expression, and regulation. New and updated sections on genetic analysis, molecular genetics, probability in genetics, and pathogenicity islands ensure that students are kept up-to-date on current key topics. The text also provides students with a sense of the social and historical context in which genetics has developed. The updated companion web site provides numerous study tools, such as animated flashcards, crosswords, practice quizzes and more! New and expanded end-of-chapter material allows for a mastery of key genetics concepts and is ideal for homework assignments and in-class discussion.

Human Evolutionary Genetics

Human Evolutionary Genetics Book
Author : Mark A. Jobling,Matthew Hurles,Chris Tyler-Smith
Publisher : Garland Pub
Release : 2004
ISBN : 9780815341857
Language : En, Es, Fr & De

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Book Description :

'Human Evolutionary Genetics' describes the molecular basis of human genetic variation and the mechanisms which give rise to it. It introduces principles behind the use of molecular genetic data to understand human evolution and population histories.

Human Genetics

Human Genetics Book
Author : Russ Hodge
Publisher : Infobase Publishing
Release : 2010-01-01
ISBN : 0816066825
Language : En, Es, Fr & De

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Book Description :

Describes modern developments in the field of genetics, discussing the mapping of the human genome, the genetic causes of afflictions, and genetic modification.