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Human Microbiota In Health And Disease

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Human Microbiota in Health and Disease

Human Microbiota in Health and Disease Book
Author : Bryan Tungland
Publisher : Academic Press
Release : 2018-05-25
ISBN : 0128146508
Language : En, Es, Fr & De

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Book Description :

Human Gut Microbiota in Health and Disease: From Pathogenesis to Therapy is a comprehensive discussion on all the aspects associated with the early colonization of gut microbiota, its development and maintenance, and its symbiotic relationship with the host in promoting health. Chapters illustrate the complex mechanisms and metabolic signaling pathways related to how the gut microbiota maintain proper regulation of glucose, lipid and energy homeostasis and immune response, all while mediating inflammatory processes involved in the etiology of many chronic disease conditions. With today's common use of pharmaceutical medicine in treating symptoms and frequent overuse of antibiotics in chronic disease within mainstream medical practice, our understanding of the etiological mechanisms of dysbiosis-induced chronic disease and natural approaches to prevention and potential cures for these diseases is of vital importance to overall human health. Details the complex relationship between human microbiota in the gut, oral cavity and skin as well as their colonization, development and impact of factors that influence the relationship Illustrates the mechanisms associated with dysbiosis-associated inflammation and its role in the onset and progression in chronic disease Provides the primary mechanisms and comprehensive scientific evidence for the use of dietary modification and pro- and prebiotics in preventing chronic disease

The Human Microbiota in Health and Disease

The Human Microbiota in Health and Disease Book
Author : Mike Wilson
Publisher : Garland Science
Release : 2018-08-20
ISBN : 9780815345855
Language : En, Es, Fr & De

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Book Description :

A human being is a symbiotic system that consists of a mammalian component interacting with a multiplicity of microbes, collectively referred to as the microbiota. The microbiota associated with humans is comprised of a variety of communities, the composition of each being dependant on the particular body site it inhabits. This book describes the various communities inhabiting humans as well as their important roles in human health and disease. An ecological approach has been adopted throughout the book to explain why the microbial community at a particular body site has a particular composition when in balance with the host (eubiosis), and why certain factors can disrupt the balance and induce dysbiosis. The techniques used to determine microbial community composition are discussed and a chapter is devoted to the many factors that underlie this mammalian-microbe symbiosis. The Human Microbiome In Health And Disease is aimed at senior undergraduates and graduates whose courses include a module on the indigenous microbiota of humans. It will also be useful to professional scientists, clinicians, and others who are keen to know more about the human microbiota and its role in health and disease.

The Human Microbiota in Health and Disease

The Human Microbiota in Health and Disease Book
Author : Mike Wilson
Publisher : Garland Science
Release : 2018-09-03
ISBN : 1351068342
Language : En, Es, Fr & De

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Book Description :

A human being consists of a mammalian component and a multiplicity of microbes, collectively referred to as the "microbiota" or "microbiome," with which it has a symbiotic relationship. The microbiota is comprised of a variety of communities, the composition of each being dependent on the body site it inhabits. This community variation arises because the numerous locations on a human being provide very different environments, each of which favors the establishment of a distinct microbial community. Each community consists of bacteria, fungi and viruses with, in some cases, archaea and/or protozoa. It is increasingly being recognized that the indigenous microbiota plays an important role in maintaining the health of its human host. However, changes in the overall composition of a microbial community at a body site, or an increase in the proportion of a particular species in that community, can result in disease or other adverse consequences for the host. The Human Microbiota in Health and Disease: An Ecological and Community-Based Approach describes the nature of the various communities inhabiting humans as well as the important roles they play in human health and disease. It discusses techniques used to determine microbial community composition and features a chapter devoted to the many factors that underlie this mammalian–microbe symbiosis. Uniquely, the book adopts an ecological approach to examining the microbial community’s composition at a particular body site and why certain factors can shift a community from a eubiotic to a dysbiotic state. The book is for undergraduates and postgraduates on courses with a module on the indigenous microbiota of humans. It will also be useful to scientists, clinicians, and others seeking information on the human microbiota and its role in health and disease.

The Human Microbiota and Microbiome

The Human Microbiota and Microbiome Book
Author : Julian R Marchesi
Publisher : CABI
Release : 2014-05-14
ISBN : 1780640498
Language : En, Es, Fr & De

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Book Description :

Thousands of different microbial species colonize the human body, and are essential for our survival. This book presents a review of the current understanding of human microbiomes, the functions that they bring to the host, how we can model them, their role in health and disease and the methods used to explore them. Current research into areas such as the long-term effect of antibiotics makes this a subject of considerable interest. This title is essential reading for researchers and students of microbiology.

The Human Microbiota

The Human Microbiota Book
Author : David N. Fredricks
Publisher : John Wiley & Sons
Release : 2013-02-22
ISBN : 1118409809
Language : En, Es, Fr & De

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Book Description :

The Human Microbiota offers a comprehensive review of all human-associated microbial niches in a single volume, focusing on what modern tools in molecular microbiology are revealing about human microbiota, and how specific microbial communities can be associated with either beneficial effects or diseases. An excellent resource for microbiologists, physicians, infectious disease specialists, and others in the field, the book describes the latest research findings and evaluates the most innovative research approaches and technologies. Perspectives from pioneers in human microbial ecology are provided throughout.

Microbiota in health and disease from pregnancy to childhood

Microbiota in health and disease  from pregnancy to childhood Book
Author : Pamela D. Browne,Eric Claassen,Michael D. Cabana
Publisher : Wageningen Academic Publishers
Release : 2017-07-20
ISBN : 9086868398
Language : En, Es, Fr & De

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Book Description :

This book offers a state-of-the-art overview of the vital relationship between human microbiota and infant and child health. Renowned clinical-experimental experts in this field discuss the development of microbiota during early life and review the environmental inputs that affect the developing infant’s gut microbiota, such as early diet and (postnatal) medical interventions. They further describe the interplay between gut microbiota and functional systems of the body, from the immune system to the central nervous system. The book discusses a range of infant and childhood diseases that are associated with microbial changes or dysbiosis, such as gastrointestinal disorders, allergic diseases, autoimmune disorders and respiratory disorders. Additionally mechanisms by which microbial dysbiosis may influence behaviour in infants are discussed. Other topics include the use of current tools in molecular microbiology for microbiota-related research and clinical practice. In the management of particular paediatric disorders, the potential of microbial manipulation with pre- and probiotics during infancy and childhood is increasingly being investigated. This book presents the evidence supporting their use in practice and reviews safety aspects. Microbiota in health and disease: from pregnancy to childhood has the ambition to provide the reader with an overview of the most recent and stunning advances in the field of infant and child microbiota and their role in health, disease and prevention. As such, it is an excellent resource for health care professionals, students and researchers in the field of life sciences.

The Gut Microbiome in Health and Disease

The Gut Microbiome in Health and Disease Book
Author : Dirk Haller
Publisher : Springer
Release : 2018-07-27
ISBN : 3319905457
Language : En, Es, Fr & De

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Book Description :

The book provides an overview on how the gut microbiome contributes to human health. The readers will get profound knowledge on the connection between intestinal microbiota and immune defense systems. The tools of choice to study the ecology of these highly-specialized microorganism communities such as high-throughput sequencing and metagenomic mining will be presented. In addition the most common diseases associated to the composition of the gut flora are discussed in detail. The book will address researchers, clinicians and advanced students working in biomedicine, microbiology and immunology.

The Human Microbiota and Chronic Disease

The Human Microbiota and Chronic Disease Book
Author : Luigi Nibali,Brian Henderson
Publisher : John Wiley & Sons
Release : 2016-09-26
ISBN : 1118982878
Language : En, Es, Fr & De

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Book Description :

Microbiota-associated pathology can be a direct result of changes in general bacterial composition, such as might be found in periodontitis and bacterial vaginosis, and/or as the result of colonization and/or overgrowth of so called keystone species. The disruption in the composition of the normal human microbiota, or dysbiosis, plays an integral role in human health and human disease. The Human Microbiota and Human Chronic Disease: Dysbioses as a Cause of Human Pathology discusses the role of the microbiota in maintaining human health. The text introduces the reader to the biology of microbial dysbiosis and its potential role in both bacterial disease and in idiopathic chronic disease states. Divided into five sections, the text delineates the concept of the human bacterial microbiota with particular attention being paid to the microbiotae of the gut, oral cavity and skin. A key methodology for exploring the microbiota, metagenomics, is also described. The book then shows the reader the cellular, molecular and genetic complexities of the bacterial microbiota, its myriad connections with the host and how these can maintain tissue homeostasis. Chapters then consider the role of dysbioses in human disease states, dealing with two of the commonest bacterial diseases of humanity – periodontitis and bacterial vaginosis. The composition of some, if not all microbiotas can be controlled by the diet and this is also dealt with in this section. The discussion moves on to the major ‘idiopathic’ diseases afflicting humans, and the potential role that dysbiosis could play in their induction and chronicity. The book then concludes with the therapeutic potential of manipulating the microbiota, introducing the concepts of probiotics, prebiotics and the administration of healthy human faeces (faecal microbiota transplantation), and then hypothesizes as to the future of medical treatment viewed from a microbiota-centric position. Provides an introduction to dysbiosis, or a disruption in the composition of the normal human microbiota Explains how microbiota-associated pathology and other chronic diseases can result from changes in general bacterial composition Explores the relationship humans have with their microbiota, and its significance in human health and disease Covers host genetic variants and their role in the composition of human microbial biofilms, integral to the relationship between human health and human disease Authored and edited by leaders in the field, The Human Microbiota and Human Chronic Disease will be an invaluable resource for clinicians, pathologists, immunologists, cell and molecular biologists, biochemists, and system biologists studying cellular and molecular bases of human diseases.

Xenobiotics and the Gut Microbiome in Health and Disease

Xenobiotics and the Gut Microbiome in Health and Disease Book
Author : Stephen J. Pandol,Zhaoping Li
Publisher : Frontiers Media SA
Release : 2019-10-14
ISBN : 288963082X
Language : En, Es, Fr & De

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Book Description :

Download Xenobiotics and the Gut Microbiome in Health and Disease book written by Stephen J. Pandol,Zhaoping Li, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Gut Microbiome in Health and Disease

The Gut Microbiome in Health and Disease Book
Author : Nathan W. Schmidt,Venkatakrishna Rao Jala,Michele Marie Kosiewicz,Pascale Alard
Publisher : Frontiers Media SA
Release : 2019-12-24
ISBN : 288963003X
Language : En, Es, Fr & De

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Book Description :

Download The Gut Microbiome in Health and Disease book written by Nathan W. Schmidt,Venkatakrishna Rao Jala,Michele Marie Kosiewicz,Pascale Alard, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Microbiota of the Human Body

Microbiota of the Human Body Book
Author : Andreas Schwiertz
Publisher : Springer
Release : 2016-05-09
ISBN : 3319312480
Language : En, Es, Fr & De

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Book Description :

Microbes can now be found in nearly every niche the human body offers. However, the complexity of the microbiota of a given site depends on the particular environmental condition thereof. Only microbes which are able to grow under these conditions, will prevail. Recent publications imply that the microorganisms do not only have multiple, critical consequences for host physiological processes such as postnatal development, immunomodulation and energy supply, but also effects on neurodevelopment, behavior and cognition. Within this book we will focus on the techniques behind these developments, epigenomics and on the various parts of the human body which are inhabited by microorganism such as the mouth, the gut, the skin and the vagina. In addition, chapters are dedicated to the possible manipulations of the microbiota by probiotics, prebiotics and faecal transplantation.

Neurodegenerative Diseases and the Human Microbiota

Neurodegenerative Diseases and the Human Microbiota Book
Author : luis Carrasco
Publisher : Editorial Hélice
Release : 2021-01-30
ISBN : 8492914505
Language : En, Es, Fr & De

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Book Description :

Recent years have seen an explosion of interest in the relationship between the microbiota – the trillions of microorganisms that inhabit the human body – and the host, both in health and disease. The microbiota comprises a complex community or ecosystem of microorganisms that colonize external tissues, such as skin, hair and nails, and internal tissues including the intestine and the vaginal and conjunctiva mucosa. The microorganisms that make up the human microbiota include viruses, bacteria, archaea, fungi and, to a lesser extent, protozoa. The largest number of microorganisms are found in the digestive tract, with the majority in the oral and nasopharyngeal cavity and in the intestine. The composition of the microbiota varies greatly between individuals and also varies in the same person depending on age, on diet and lifestyle, and even on the state of the person’s health. Not surprisingly, the microbiota influences many physiological functions beyond food metabolism, and can affect both the immune system and the nervous system. The microbiota composition may be imbalanced (dysbiosis) in patients with different pathologies, and can play an important role in the severity of different clinical symptoms. In this book, we introduce a new concept in the field of human microbiota in health and disease. The fundamental idea is that both fungi and bacteria can be found in some internal tissues that should be "sterile", which can lead to polymicrobial infections. In the absence of symptoms, these infections may go unnoticed over many years or decades. However, if the number of fungi and/or bacteria in a given tissue increases due to, for example, stress, changes in diet, lifestyle, etc., clinical symptoms may begin to emerge, which can vary greatly depending on the affected tissue. This diversity in symptoms will also depend on the specific species of fungi and/or bacteria that affect each individual. The internal microbiota may be the root cause of numerous diseases in humans whose etiology is still unknown. Among these diseases, we can include neurodegenerative, cardiovascular, ophthalmological, rheumatic and allergic diseases, among others. This concept has been studied and published in many different scientific works of our research group in recent years. We have determined the species of fungi and bacteria that can exist in the nervous system – mainly in the brain of patients with different neurodegenerative diseases (NGDs) such as Alzheimer's, Parkinson's and Huntington's disease, amyotrophic lateral sclerosis (ALS) and multiple sclerosis. In this book, I first present an overview of this concept and I then indicate the potential possibilities for proper diagnosis and more appropriate treatments for these human diseases whose cause remains unknown. The treatment of polymicrobial infections in internal tissues is very complex and it will take some years to determine the most appropriate therapeutic strategy to combat them. At the moment, it is more about laying the foundations to determine the etiology of these diseases and initiating new lines of research aimed at elucidating the most effective therapeutic options.

Exploring Networks of the Human Microbiota in Health and Disease

Exploring Networks of the Human Microbiota in Health and Disease Book
Author : Virginia Fairclough
Publisher : Unknown
Release : 2016
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Exploring Networks of the Human Microbiota in Health and Disease book written by Virginia Fairclough, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Intestinal Microbiota in Health and Disease

Intestinal Microbiota in Health and Disease Book
Author : Eduardo J. Schiffrin,Philippe Marteau,Dominique Brassart
Publisher : CRC Press
Release : 2014-02-11
ISBN : 1482226774
Language : En, Es, Fr & De

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Book Description :

Now considered an organ with defensive and metabolic capabilities, the intestinal microbiota plays a major role in the local host immune system development and education. It contributes to the generation of a homeostatic balance characterized by the capacity to react against pathogens while remaining hyperresponsive/tolerant against commensals. This homeostatic response depends on bacteria and bacterial product sensing by innate immune cells and their molecular asset at the intestinal mucosa. This book captures the enormous progress that has been accomplished in this field in recent years.

The Human Microbiome in Early Life

The Human Microbiome in Early Life Book
Author : Omry Koren,Samuli Rautava
Publisher : Academic Press
Release : 2020-09-18
ISBN : 0128180986
Language : En, Es, Fr & De

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Book Description :

The Human Microbiome in Early Life: Implications to Health and Disease presents recent research advances that have highlighted the significance of early life, possibly beginning before birth, in the establishment of both the microbiome and its role in health and disease. The book reviews current knowledge on the origins of the human microbiota in early life, presents exposures which may disturb normal microbial colonization, and covers their implications to the risk of disease. Finally, emerging means to modify the early human microbiome to improve health are discussed. Examines the timeline of the human microbiome, from before conception to infancy, with an emphasis on clinical implications Evaluates the effort to understand not only the composition but also the origin of the microbiome Proves the emerging means to modify the human microbiome and particularly ‘the first 1000 days of life’ improve human health and prevent disease Generates resources to facilitate characterization of the human microbiota to further our understanding of how the microbiome impacts human health and disease

Human microbiota Interactions in Health and Disease

Human microbiota Interactions in Health and Disease Book
Author : Matthew Geoffrey Collison
Publisher : Unknown
Release : 2018
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Human microbiota Interactions in Health and Disease book written by Matthew Geoffrey Collison, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Human Microbiome Handbook

The Human Microbiome Handbook Book
Author : Jason Tetro,Emma Allen-Vercoe
Publisher : DEStech Publications, Inc
Release : 2016-03-15
ISBN : 1605951595
Language : En, Es, Fr & De

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Book Description :

Critical reference explains strategies of microbiome research in humansSummarizes the microbiome's effects on immunity, metabolism, genetics and psychologyEvaluates medical and nutritional therapies for modifying the microbiomeFor healthcare researchers, nutritionists, microbiologists, and medical professionals Written by a team of leading scientists, this book offers a concise technical reference covering human microbiome research and its ramifications for medicine and nutrition. The initial chapters furnish a scientific explanation of the microbiome in general and its ecology. The book then provides a detailed investigation of microbial populations as these pertain to physiology, metabolism and immunology. The final portions are devoted to exploration of the microbiome's effects on chronic and autoimmune diseases and include assessments of clinical therapies and nutritional interventions designed to alter the microbiome to mitigate chronic health conditions.

Gut Microbiome and Its Impact on Health and Diseases

Gut Microbiome and Its Impact on Health and Diseases Book
Author : Debabrata Biswas,Shaik O. Rahaman
Publisher : Springer Nature
Release : 2020-08-27
ISBN : 3030473848
Language : En, Es, Fr & De

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Book Description :

This book provides a comprehensive examination of the role of gut microbiome/microflora in nutrition, metabolism, disease prevention and health issues, including farm animal health and food value, and human gastrointestinal health and immunity. Indigenous microbiotas, particularly the gut microflora/microbiome, are an essential component in the modern concept of human and animal health. The diet and lifestyle of the host and environment have direct impact on gut microflora and the patterns of gut microbial colonization associated with health and diseases have been documented. Contributing authors cover the impact of gut microbiome in farm animal health, and explore the possibility of modulating the human gut microbiome with better animal products to prevent human diseases, including endemic and emerging diseases such as obesity, cancer and cardiac diseases. Dieting plan and control methods are examined, with attention paid to balance dieting with natural food and drink components. In addition, the role of gut microbiota in enteric microbial colonization and infections in farm animals is also discussed. The volume also explores the possibility of improving human health by modulating the microbiome with better food, including bio-active foods and appropriate forms of intake. Throughout the chapters, authors examine cutting edge research and technology, as well as future directions for better practices regarding emerging issues, such as the safety and production of organic food.

Role of Microbes in Human Health and Diseases

Role of Microbes in Human Health and Diseases Book
Author : Nar Singh Chauhan
Publisher : BoD – Books on Demand
Release : 2019-06-05
ISBN : 1838802339
Language : En, Es, Fr & De

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Book Description :

Microbes are ubiquitous and have ecological interactions with almost all life forms. Likewise, humans invariably engage in host-microbial interactions that could induce short-term or long-term effects. Some of these long-term crossover interactions have allowed successful colonization of microbes within or on the human body, collectively known as the human microbiome or human microbiota. The human microbiome is identified as playing a key role in various physiological processes like digestion, immunity, defense, growth, and development. Any dysbiosis in the human microbiome structure could induce the onset of various metabolic or physiological disorders. Cumulatively, the human microbiome is considered as a virtual human organ that is essential for host survival. Additionally, short-term biological interactions of the host and microbes have exposed microbes to the human cellular system. This exposure could have allowed the microbes to invade human cells for their growth and reproduction-induced onset of various infectious diseases. This book incorporates a number of studies highlighting the role of microbes in human health and diseases.

Marsh and Martin s Oral Microbiology E Book

Marsh and Martin s Oral Microbiology   E Book Book
Author : Philip D. Marsh,Michael A. O. Lewis,Helen Rogers,Dr David Williams, BSC (Hons) PhD,Melanie Wilson
Publisher : Churchill Livingstone
Release : 2016-05-13
ISBN : 0702061743
Language : En, Es, Fr & De

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Book Description :

Now expanded with the latest information of relevance to current dental practice, Oral Microbiology retains its unique ecological approach to the subject which helps the reader determine whether an organism will have a pathogenic or commensal relationship at a given site. In the new edition, greater emphasis is placed on the role of current molecular biology techniques in the understanding of oral microbes. The book also provides insight into current therapeutic and prophylactic antibiotic use, infection control, and the relationships between oral and general health. Oral Microbiology provides comprehensive coverage of the subject which will be essential to readers with a specific interest in dentistry as well as those with a more general interest in host-microbe interactions and in microbial ecology. The book is suitable for undergraduate and postgraduate dental students, research workers, and a wide range of clinical dental professionals. Full coverage of the latest molecular biology techniques which have revolutionized our knowledge of oral microbes Exploration of the biological and clinical significance of the oral microflora in the form of a biofilm on dental and mucosal surfaces Contemporary views on therapeutic and prophylactic antibiotic use, infection control, and the relationships between oral and general health