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Human Aging

Human Aging Book
Author : Calogero Caruso,Giuseppina Candore
Publisher : Academic Press
Release : 2021-05-21
ISBN : 0128227370
Language : En, Es, Fr & De

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Book Description :

Human Aging: From Cellular Mechanisms to Therapeutic Strategies offers an exhaustive picture of all the biological aspects of human aging by describing the key mechanisms associated with human aging and covering events that could disrupt the normal course of aging. Each chapter includes a summary of the salient points covered, along with futures prospects. The book provides readers with the information they need to gain or deepen the skills needed to evaluate the mechanisms of aging and age-related diseases and to monitor the effectiveness of therapies aimed at slowing aging. The book encourages PhD and Postdoc students, researchers, health professionals and others interested in the biology of aging to explore the fascinating and challenging questions about why and how we age as well as what can and cannot be done about it. Concentrates on different processes, e.g., oxidative stress, cellular senescence and Inflammaging Offers the ability to access cross-sectional knowledge more easily Written by expert researchers in biogerontology who are actively involved in various fields within aging research

Human Aging

Human Aging Book
Author : Paul W. Foos,M. Cherie Clark
Publisher : Routledge
Release : 2016-01-08
ISBN : 131735107X
Language : En, Es, Fr & De

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Book Description :

This text offers a readable and friendly presentation of the important methods, findings, and theories of human aging, while actively involving the reader in meaningful exercises and critical thinking. Students are repeatedly challenged to apply information in the text to the older adults in their own lives. Specifically, suggestions for enhancing the lives of their older relatives are offered and encouraged. These include guidelines for discussions they might have regarding social, emotional, and environmental changes as well encouraging intellectual and social interaction. In this Edition: Emphasis on the science of the study of aging and why questions in aging are difficult to answer, how social scientists attempt to handle such difficulties, and the successes and failures social scientists have had thus far in answering those questions. The text also demonstrates how current research findings are now being applied in the real world and/or how they might be applied in the future. Cross-cultural comparisons and ethnic group comparisons are included wherever possible. Each chapter begins with "Senior View," which introduces students to a real person and gives them a chance to hear what older adults think and say about important issues related to the chapter and a chance to compare those opinions to the research findings. Each chapter ends with "Making Choices," emphasizing the important behavioral, emotional, and social choices that students can make now to prolong a healthy, happy life. "Chapter Projects" offer the opportunity for active learning, as students investigate for themselves an issue related to the chapter. Instructors can expand these projects for students who want to learn more, or for independent study. "Focus on Aging" boxes compliment the material in the text, providing additional insight and examples, and encouraging critical thinking. Every chapter includes discussion questions, study questions, chapter exercises, and related online resources.

Ending Aging

Ending Aging Book
Author : Aubrey de Grey,Michael Rae
Publisher : St. Martin's Press
Release : 2007-09-04
ISBN : 9781429931830
Language : En, Es, Fr & De

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Book Description :

MUST WE AGE? A long life in a healthy, vigorous, youthful body has always been one of humanity's greatest dreams. Recent progress in genetic manipulations and calorie-restricted diets in laboratory animals hold forth the promise that someday science will enable us to exert total control over our own biological aging. Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process, extending our productive, youthful lives. Dr. Aubrey de Grey is perhaps the most bullish of all such researchers. As has been reported in media outlets ranging from 60 Minutes to The New York Times, Dr. de Grey believes that the key biomedical technology required to eliminate aging-derived debilitation and death entirely—technology that would not only slow but periodically reverse age-related physiological decay, leaving us biologically young into an indefinite future—is now within reach. In Ending Aging, Dr. de Grey and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage. As with man-made machines, this damage can periodically be repaired, leading to indefinite extension of the machine's fully functional lifetime, just as is routinely done with classic cars. We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage. By demystifying aging and its postponement for the nonspecialist reader, de Grey and Rae systematically dismantle the fatalist presumption that aging will forever defeat the efforts of medical science.

Biology of Human Aging

Biology of Human Aging Book
Author : Alexander P. Spence
Publisher : Benjamin-Cummings Publishing Company
Release : 1995
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

For one-semester introductory-level courses in the Biology of Human Aging, for non-majors. A general — yet substantive — overview of the aging process, this text explores age-related changes and age-related dysfunctions common to each body system. Scientific terminology is kept to a minimum.

Biomarkers of Human Aging

Biomarkers of Human Aging Book
Author : Alexey Moskalev
Publisher : Springer Nature
Release : 2019-09-13
ISBN : 3030249700
Language : En, Es, Fr & De

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Book Description :

This book collects and reviews, for the first time, a wide range of advances in the area of human aging biomarkers. This accumulated data allows researchers to assess the rate of aging processes in various organs and systems, and to individually monitor the effectiveness of therapies intended to slow aging. In an introductory chapter, the editor defines biomarkers of aging as molecular, cellular and physiological parameters that demonstrate reproducible changes - quantitative or qualitative - with age. The introduction recounts a study which aimed to create a universal model of biological age, whose most predictive parameters were albumin and alkaline phosphatase (indication liver function), glucose (metabolic syndrome), erythrocytes (respiratory function) and urea (renal function). The book goes on to describe DNA methylation, known as the “epigenetic clock,” as currently the most comprehensive predictor of total mortality. It is also useful for predicting mortality from cancer and cardiovascular diseases, and for analyzing the effects of lifestyle factors including diet, exercise, and education. Individual contributions draw additional insight from research on genetics and epigenetic aging markers, and immunosenescence and inflammaging markers. A concluding chapter outlines the challenge of integrating of biological and clinical markers of aging. Biomarkers of Human Aging is written for professionals and practitioners engaged in the study of aging, and will be useful to both advanced students and researchers.

The Future of Aging

The Future of Aging Book
Author : Anonim
Publisher : Springer Science & Business Media
Release : 2010-08-17
ISBN : 9048139988
Language : En, Es, Fr & De

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Book Description :

Just as the health costs of aging threaten to bankrupt developed countries, this book makes the scientific case that a biological "bailout" could be on the way, and that human aging can be different in the future than it is today. Here 40 authors argue how our improving understanding of the biology of aging and selected technologies should enable the successful use of many different and complementary methods for ameliorating aging, and why such interventions are appropriate based on our current historical, anthropological, philosophical, ethical, evolutionary, and biological context. Challenging concepts are presented together with in-depth reviews and paradigm-breaking proposals that collectively illustrate the potential for changing aging as never before. The proposals extend from today to a future many decades from now in which the control of aging may become effectively complete. Examples include sirtuin-modulating pills, new concepts for attacking cardiovascular disease and cancer, mitochondrial rejuvenation, stem cell therapies and regeneration, tissue reconstruction, telomere maintenance, prevention of immunosenescence, extracellular rejuvenation, artificial DNA repair, and full deployment of nanotechnology. The Future of Aging will make you think about aging differently and is a challenge to all of us to open our eyes to the future therapeutic potential of biogerontology.

Experimental Psychology Cognition and Human Aging

Experimental Psychology  Cognition  and Human Aging Book
Author : Donald H. Kausler
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 1461396956
Language : En, Es, Fr & De

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Book Description :

This book is a major revision and extension of my earlier book, Experimental Psychology and Human Aging, which appeared in 1982. The intervening years have seen a remarkable expansion of psychological research on human aging, especially on topics dealing with cognition. They have also seen research on cognitive aging gain increasing importance within the mainstream of basic cognitive research. As my lecture notes for my course in the psychology of aging grew, so did my apprehension regarding the task ahead of me in revis ing the first edition. The research explosion in cognitive aging forced several major changes in content from the first to the second edition. Two chapters on learning and memory in the first edition were necessarily expanded to six chapters in the present edition. Similarly, the single prior chapter on percep tion and attention became two chapters, as did the single prior chapter on thinking. Another change from the first edition is in the addition of some review of the effects of abnormal aging on various cognitive processes, parti cularly in regard to memory functioning. To keep the revision within reason able length, some sacrifices had to be made. The multiple chapters on metho dology and theory in the first edition were condensed into the present, single chapter. However, the major topics from the first edition were retained and, in fact, added to by the inclusion of important topics and issues that emerged over the past eight years.

Long lived Proteins in Human Aging and Disease

Long lived Proteins in Human Aging and Disease Book
Author : Roger J. W. Truscott
Publisher : John Wiley & Sons
Release : 2021-02-16
ISBN : 3527347283
Language : En, Es, Fr & De

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Book Description :

This authoritative overview on an emerging topic in the molecular life sciences covers all aspects of the aging of (long-lived) proteins. It describes the molecular mechanisms of aging on the protein level, in particular the most common side chain modifications and includes analytical methods to study protein half-life and the accumulation of modifications. Finally, the impact of protein aging on several age-related disases in humans is dissected, and their role in limiting human lifespan is discussed.

Human Aging

Human Aging Book
Author : Augustine Gaspar DiGiovanna
Publisher : McGraw-Hill Science, Engineering & Mathematics
Release : 2000
ISBN : 9780072926910
Language : En, Es, Fr & De

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Book Description :

With the growing size of the elderly population comes an increased interest in aging as a subject of research and study. Human Aging: Biological Perspectives is written for the one-quarter or one-semester introductory level course and is aimed at students with little or no science background. The main structure of the text follows a body systems approach. In addition to the introductory chapter and a chapter covering molecules, cells, and the theories of aging, each body system is covered in its own chapter.

Time of Our Lives The Science of Human Aging

Time of Our Lives   The Science of Human Aging Book
Author : Tom Kirkwood Professor of Biological Gerontology University of Manchester
Publisher : Oxford University Press, USA
Release : 1999-06-23
ISBN : 019802939X
Language : En, Es, Fr & De

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Book Description :

As recent articles about "the graying of America" suggest, a demographic revolution is well underway. The number of people living into extreme old age is increasing dramatically. By the year 2050 one in five of the world's population, including the developing countries, will be 65 or older, a fact which presages profound medical, biological, philosophical, and political changes in the coming century. In Time of Our Lives, Tom Kirkwood unfolds some of the deepest mysteries of medical science while demolishing some of the most persistent misconceptions. He overturns the almost universally held belief that aging is either necessary or inevitable--it isn't--and debunks the idea that there exists a "death gene" that evolved to inhibit population growth. Instead, Kirkwood shows that we age because our genes, evolving at a time when life was "nasty, brutish, and short," placed little priority on the long-term maintenance of our bodies. With such knowledge, along with new insights from genome research, we can devise ways to target the root causes of aging and of age-related diseases such as Alzheimer's and osteoporosis. Expanding his thesis of the "disposable soma," developed over twenty years of research, Kirkwood makes sense of the evolution of aging, explains how aging occurs, and answers fundamental questions like why women live longer than men. He even considers the possibility that human beings will someday have greatly extended life spans or even be free from senescence altogether. Beautifully written by one of the world's pioneering researchers into the science of aging, Time of Our Lives is a clear, original and, above all, inspiring investigation of a process all of us experience but few of us understand.

The Telomerase Revolution

The Telomerase Revolution Book
Author : Michael Fossel
Publisher : BenBella Books, Inc.
Release : 2015-10-06
ISBN : 1941631703
Language : En, Es, Fr & De

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Book Description :

One of Wall Street Journal's "Best Books for Science Lovers" in 2015 Science is on the cusp of a revolutionary breakthrough. We now understand more about aging—and how to prevent and reverse it—than ever before. In recent years, our understanding of the nature of aging has grown exponentially, and dramatic life extension—even age reversal—has moved from science fiction to real possibility. Dr. Michael Fossel has been in the forefront of aging research for decades and is the author of the definitive textbook on human aging. In The Telomerase Revolution, he takes us on a detailed but highly accessible scientific journey, providing startling insights into the nature of human aging. Twenty years ago, there was still considerable debate of the nature of human aging, with a variety of competing theories in play. But scientific consensus is forming around the telomere theory of aging. The essence of this theory is that human aging is the result of cellular aging. Every time a cell reproduces, its telomeres (the tips of the chromosomes) shorten. With every shortening of the telomeres, the cell's ability to repair its molecules decreases. It ages. Human aging is the result of the aging of the body's trillions of cells. But some of our cells don't age. Sex cells and stem cells can reproduce indefinitely, without aging, because they create telomerase. Telomerase re-lengthens the telomeres, keeping these cells young. The Telomerase Revolution describes how telomerase will soon be used as a powerful therapeutic tool, with the potential to dramatically extend life spans and even reverse human aging. Telomerase-based treatments are already available, and have shown early promise, but much more potent treatments will become available over the next decade. The Telomerase Revolution is the definitive work on the latest science on human aging, covering both the theory and the clinical implications. It takes the reader to the forefront of the upcoming revolution in human medicine.

Conn s Handbook of Models for Human Aging

Conn s Handbook of Models for Human Aging Book
Author : Jeffrey L. Ram,P. Michael Conn
Publisher : Academic Press
Release : 2018-04-05
ISBN : 0128113545
Language : En, Es, Fr & De

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Book Description :

Conn's Handbook of Models for Human Aging, Second Edition, presents key aspects of biology, nutrition, factors affecting lifespan, methods of age determination, use in research and the disadvantages/advantages of use. Using a multidisciplinary approach, this updated edition is designed as the only comprehensive, current work that covers the diversity in aging models. Chapters on comparative models explore age-related diseases, including Alzheimer's, joint disease, cataracts, cancer and obesity. Also included are new tricks and approaches not available in primary publications. This must-have handbook is an indispensable resource for researchers interested in the mechanisms of aging, gerontologists, health professionals, allied health practitioners and students. Combines both the methods of study for human aging and animal models Provides a historical overview and discussion of model availability, key methods and ethical issues Contains over 200 full color illustrations

Human Aging

Human Aging Book
Author : Paul W. Foos
Publisher : Unknown
Release : 2016
ISBN : 9781315665092
Language : En, Es, Fr & De

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Book Description :

Download Human Aging book written by Paul W. Foos, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Werner s Syndrome and Human Aging

Werner   s Syndrome and Human Aging Book
Author : Darrell Salk
Publisher : Springer Science & Business Media
Release : 2013-03-13
ISBN : 1468478532
Language : En, Es, Fr & De

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Book Description :

Download Werner s Syndrome and Human Aging book written by Darrell Salk, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Social Policy for an Aging Society

Social Policy for an Aging Society Book
Author : Carole B. Cox,Carole B. Cox, PhD
Publisher : Springer Publishing Company
Release : 2015-01-16
ISBN : 0826196535
Language : En, Es, Fr & De

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Book Description :

As people age, they are at increased risk of having their basic human rights threatened or violated. When age is perceived as incompetence, it can easily lead to discrimination that impacts human rights. Based on the premise that social policy must reflect human rights principles, this graduate-level textbook views the challenges associated with aging as opportunities for policy development that stresses the rights of older adults rather than needs. The text distinguishes between “needs” and “rights” and describes those policies and services that best ensure that the rights of older adults are actually met—particularly programs that enable people to remain in their own communities so they can benefit from continued integration and participation in society. Issues and challenges surrounding such efforts, and gaps in social policies faced by specific subsets of older people, are critically examined. The book first analyzes current aging policies and rights and considers the Older Americans Act as a basic policy framework. With an eye to promoting independence, the book discusses issues of income, housing, transportation, health, and home care and what constitutes a “livable community,” along with policies that promote wellbeing and focus on preventing senior abuse and exploitation. Challenges faced by older workers are covered, as are issues particular to family caregivers, older women, and grandparents as caregivers. Gaps in social policies for LG BT seniors and older members of specific ethnic groups are discussed. Particular attention is given to global issues and aging policies in diverse countries and the ways in which they reflect human rights concerns. Each chapter concludes with probing discussion questions for classroom use. KEY FEATURES: Presents a human rights framework for aging policy Distinguishes between needs and rights of older persons Focuses on policies and programs that can help older people to remain in the community Explores the issues and challenges of specific older populations Discusses global responses and concerns with regard to older persons and human rights Carole B. Cox, MSW, PhD, is professor at the Graduate School of Social Service, Fordham University. She is a fellow of the Gerontological Society of America and a Fulbright scholar. She is the author of more than 50 journal articles and chapters dealing with various aspects of aging and caregiving, with extensive research on caregivers for persons with dementia, their needs, and their use of services. Her recent work includes a study of the impact of dementia on the workplace. Her caregiving research also includes that of grandparents raising grandchildren, leading to the development of a curriculum, Empowering Grandparents Raising Grandchildren: A Training Manual for Group Leaders (Springer Publishing Company, 2000). She is the editor of To Grandmother’s House We Go and Stay: Perspectives on Custodial Grandparents (Springer Publishing Company, 2000). Her other books include Home Care for the Elderly: An International Perspective, coauthored with Abraham Monk (1991); The Frail Elderly: Problems, Needs, and Community Responses (1993); Ethnicity and Social Work Practice, coauthored with Paul Ephross (1998); Community Care for an Aging Society: Policies and Services (Springer Publishing Company, 2005); and Dementia and Social Work Practice (Springer Publishing Company, 2007).

DHEA in Human Health and Aging

DHEA in Human Health and Aging Book
Author : Ronald Ross Watson
Publisher : CRC Press
Release : 2011-07-22
ISBN : 1439838844
Language : En, Es, Fr & De

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Book Description :

Reduced production of DHEA associated with the diseases that accompany aging has led to its use as a nutritional supplement for antiaging, metabolic support, and other purposes. While animal studies have clearly shown substantial benefits of DHEA in combating various disease states, the effect of low levels of DHEA in humans is less established, an

SUMMARY Ending Aging The Rejuvenation Breakthroughs That Could Reverse Human Aging In Our Lifetime By Aubrey De Grey And Michael Rae

SUMMARY   Ending Aging  The Rejuvenation Breakthroughs That Could Reverse Human Aging In Our Lifetime By Aubrey De Grey And Michael Rae Book
Author : Shortcut Edition
Publisher : Shortcut Edition
Release : 2021-06-05
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

* Our summary is short, simple and pragmatic. It allows you to have the essential ideas of a big book in less than 30 minutes. As you read this summary, you will learn that an anthropological revolution such as the world has never known is at hand: not only slowing down and stopping the aging process, but even reversing it. You will also learn that : we have been conditioned since the dawn of time by the inevitability of aging and death; of the 150,000 people who die every day in the world, 100,000 die of old age; our reactions to revolutionary progress are sometimes irrational; the acceptance of the aging process must become increasingly politically incorrect; certain cellular and molecular changes must take place if we are to fight effectively against the aging process; a militant spirit is indispensable for the diffusion of the author's theses. All scientists who study the biology of aging agree on one point: one day, relatively soon, we will be able to reverse the aging process using techniques still under study today. Among these scientists, Dr. de Grey stands out for his constancy and combativeness. His fight against aging has become his raison d'être, and this book is a kind of manifesto. In this book, the author demystifies anti-aging techniques, making them easily accessible to all. A salutary work, which has already been praised by newspapers as serious as the "Wall Street Journal" or the "New York Times". *Buy now the summary of this book for the modest price of a cup of coffee!

Adult Cognition

Adult Cognition Book
Author : Timothy A. Salthouse
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 1461394848
Language : En, Es, Fr & De

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Book Description :

For some time now, the study of cognitive development has been far and away the most active discipline within developmental psychology. Although there would be much disagreement as to the exact proportion of papers published in developmental journals that could be considered cognitive, 50% seems like a conservative estimate. Hence, a series of scholarly books to be devoted to work in cognitive development is especially appropriate at this time. The Springer Series in Cognitive Development contains two basic types of books, namely, edited collections of original chapters by several authors, and original volumes written by one author or a small group of authors. The flagship for the Springer Series is a serial publication of the "advances" type, carrying the subtitle Progress in Cognitive Development Research. Volumes in the Progress sequence are strongly thematic, in that each is limited to some well-defined domain of cognitive-developmental research (e. g. , logical and mathematical development, semantic development). All Progress volumes are edited collections. Editors of such books, upon consultation with the Series Editor, may elect to have their works published either as contributions to the Progress sequence or as separate volumes. All books written by one author or a small group of authors will be published as separate volumes within the series. A fairly broad definition of cognitive development is being used in the selection of books for this series.

human aging

human aging Book
Author : james e. birren
Publisher : Unknown
Release : 2021-09-21
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download human aging book written by james e. birren, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Human Aging

Human Aging Book
Author : Research and Education Association
Publisher : Research & Education Assn
Release : 1982
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This reference book describes the physiological and psychological changes which attend the normal aging process. A separate section is provided on the patterns of use of psychoactive drugs by the elderly. The information in this reference volume was originated by leading investigators in the field, who carried out observations on healthy persons over a period of years.