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Hla From Benchtop To Bedside

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HLA from Benchtop to Bedside

HLA from Benchtop to Bedside Book
Author : A. Bradley Eisenbrey
Publisher : Academic Press
Release : 2021-01-05
ISBN : 012824237X
Language : En, Es, Fr & De

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Book Description :

HLA from Benchtop to Bedside provides the reader with a comprehensive, concise and thoroughly up-to-date book on all aspects of the HLA system, including new techniques and methodologies. Each chapter begins with bullet point lists of principle learning points, including comprehensive references and validated links to international resources. Written by a diverse range of international academics for professionals, researchers, undergraduate and graduate students, this book is ideal for organ and stem cell transplant professionals, histocompatibility laboratory professionals and staff, medical residents and fellows on transplant services, medical students, and students in clinical laboratory science. The book's author, Dr. Arthur Bradley Eisenbrey, is an experienced transplant pathologist who has held significant academic and leadership positions in the field. Reviews current knowledge surrounding the HLA system Covers current methodologies and utilization of histocompatibility testing Authored by a leader in the field of histocompatibility and transfusion medicine

Hyperthermic Oncology from Bench to Bedside

Hyperthermic Oncology from Bench to Bedside Book
Author : Satoshi Kokura,Toshikazu Yoshikawa,Takeo Ohnishi
Publisher : Springer
Release : 2016-06-07
ISBN : 9811007195
Language : En, Es, Fr & De

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Book Description :

This comprehensive work broadens readers' understanding of the rudimentary mechanism of the anti-cancer effect of hyperthermia. It also presents state-of-the-art clinical outcomes by hyperthermia treatment of cancer. In the past few decades, basic and clinical research have shown through in vitro experiments that hyperthermia inhibits epithelial-mesenchymal transition (EMT), resulting in the prevention of metastasis. It also has been learned that hyperthermia shows its superior benefit when applied in combination with radiation therapy, chemotherapy, or various immunotherapies as treatments of several types of carcinoma. The chapters here from expert contributors describe the details of their research for each type of cancer. This book provides not only an overview and the current status of hyperthermia but also its future perspectives. Therefore this volume will greatly benefit oncologists, radiologists and radiology technologists, and chemotherapists who are involved in immunotherapy for all kinds of cancer.

Stem Cells

Stem Cells Book
Author : Anonim
Publisher : Unknown
Release : 2021-04-10
ISBN : 9814466433
Language : En, Es, Fr & De

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Book Description :

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Molecular Basis of Neuropsychiatric Disorders from Bench to Bedside

Molecular Basis of Neuropsychiatric Disorders  from Bench to Bedside Book
Author : Shafiqur Rahman
Publisher : Academic Press
Release : 2019-10-05
ISBN : 0128188561
Language : En, Es, Fr & De

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Book Description :

Progress in Molecular Biology and Translational Science, Volume 167, provides the most topical, informative and exciting monographs available on a wide variety of research topics related to Models and Biological Targets in Drug Discovery for Attention Deficit Hyperactivity Disorder, Novel Targets for Parkinson-Depression Co-morbidity. Utility of Cannabidiol (CBD) in Neuropsychiatric Disorders: A Short Review of the Recent Pre-clinical and Clinical Findings, The Many Sides of Microglia in Alcohol Use Disorders, Stress, Anxiety, Molecular Targets and More, Calcineurin Signaling in Psychiatric Disorders, Emerging Evidence for the Role of Pituitary Adenylate Cyclase- Activating Peptide (PACAP) in Neuropsychiatric Disorders, and more. Includes comprehensive coverage of molecular biology Presents ample use of tables, diagrams, schemata and color figures to enhance the reader's ability to rapidly grasp the information provided Contains contributions from renowned experts in the field

Multiple Sclerosis Bench to Bedside

Multiple Sclerosis  Bench to Bedside Book
Author : Alexzander A. A. Asea,Fabiana Geraci,Punit Kaur
Publisher : Springer
Release : 2017-01-16
ISBN : 3319478613
Language : En, Es, Fr & De

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Book Description :

Multiple Sclerosis (MS) is one of the main causes of disability in young adult population. The estimated burden of the disease worldwide is about three million people. The pathogenic mechanism of MS involves both auto immune and degenerative processes. These two mechanisms are thought to determine a combination of events leading to several clinical pattern of disease onset and course. Multiple Sclerosis: Bench to Bedside provides the most up-to-date and concise reviews on the critical issues of multiple sclerosis from around the world. This book is written by leaders and experts in the field of multiple sclerosis research and is divided into easy to read sections. Section I focuses on basic science aspects of Multiple Sclerosis, including potential biomarkers, molecular biology, heat shock proteins, oxidative stress, genetic and epigenetics. Section II focuses on clinical and epidemiological aspects of Multiple Sclerosis, including remyelination therapy, neuroplasticity-based technologies and interventions. This is an important reference book and a must-read for Postgraduate Medical Scholars, Basic Science Researchers and Neurologists in Clinical Practice.

Hematopoietic Stem Cell Therapy

Hematopoietic Stem Cell Therapy Book
Author : Edward David Ball,John W. Lister,Ping Law
Publisher : Unknown
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This book will be the only current practical guide to a widely used procedure for treating leukemias and disseminated cancers. The contents are organized chronologically, to serve as a step-by-step guide throughout the transplant process. Comprehensive yet concise, it emphasizes the latest techniques, such as peripheral blood stem cell grafts. Organises sections to correspond with the bone marrow transplant process, progressing from evaluation of the disease through evaluation of the patient, the transplant conditioning regimens, the immediate post-transplant period, and the late post-transplant period. Explores patient selection criteria, graft collection procedures, processing of grafts, therapies to enhance implantation outcomes, regulatory issues, and much more. Devotes entire chapters to specific disease entities treated by bone marrow transplant as well as individual complications that arise. Discusses the full range of transplant approaches in use today, identifies controversial areas, and offers recommendations for making treatment choices. Provides informative tables and figures in each chapter to clarify important concepts and complex procedures.

Symposium Issue

Symposium Issue Book
Author : Anonim
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Mucosal Immunity

Mucosal Immunity Book
Author : Lloyd Mayer
Publisher : Unknown
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Mucosal Immunity book written by Lloyd Mayer, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Inflammatory Bowel Diseases New Insights Into Mechanisms of Inflammation and Challenges in Diagnosis and Treatment

Inflammatory Bowel Diseases  New Insights Into Mechanisms of Inflammation and Challenges in Diagnosis and Treatment Book
Author : E. Monteiro,F. Tavarelo Veloso
Publisher : Springer
Release : 1995-07-31
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This volume contains the proceedings of Falk Symposium No. 76, held in Estoril, Portugal, May 5--7, 1994, and presents a modern aetiopathogenesis-based approach to clinical, diagnostic and therapeutic developments in inflammatory bowel disease. The first section deals with the first results of a prospective epidemiological study in the EEC countries, while subsequent sections cover the most important factors responsible for IBD, diagnosis, controversies in clinical management, new insights into therapy, and difficult clinical problems. The book closes with a state-of-the-art overview of the new knowledge as well as future perspectives regarding diagnosis and treatment. It will be of interest to all clinicians and researchers in this important area of gastroenterology.

Genetics Abstracts

Genetics Abstracts Book
Author : Anonim
Publisher : Unknown
Release : 1991
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Immunogenic Peptides of Human Telomerase Reverse Transcriptase Restricted to HLA B7

Immunogenic Peptides of Human Telomerase Reverse Transcriptase Restricted to HLA B7 Book
Author : Xochitl Cortez-Gonzalez
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Immunogenic Peptides of Human Telomerase Reverse Transcriptase Restricted to HLA B7 book written by Xochitl Cortez-Gonzalez, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Investigative Ophthalmology Visual Science

Investigative Ophthalmology   Visual Science Book
Author : Anonim
Publisher : Unknown
Release : 2001
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Liver and Biliary Diseases

Liver and Biliary Diseases Book
Author : Neil Kaplowitz
Publisher : Unknown
Release : 1996
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Liver and Biliary Diseases book written by Neil Kaplowitz, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Immuno Oncology

Immuno Oncology Book
Author : Thomas Ichim,Boris Minev,Jesus Perez Blas
Publisher : Createspace Independent Publishing Platform
Release : 2015-05-08
ISBN : 9781512115031
Language : En, Es, Fr & De

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Book Description :

The immune system offers the possibility of treating cancer and its metastasis without the toxicities of chemotherapy. Unfortunately, despite recent medical advances, overall survival of patients is still relatively dismal. Advances such development of Provenge, which is the first widely accepted immunotherapy of cancer have attracted media attention and interest, however survival advantage was only 3 months in double blind trials. In this book we take a multi-disciplinary approach to analyzing in a highly referenced and technical manner the various cellular, biochemical and immunological changes that occur in cancer patients. By categorizing what cancer does to the body, and how the body tries to fight the cancer, an overall picture is painted of various interventions and combination interventions that can be tried in order to maximize probability of patient improvement. Various conventional and unconventional approaches to cancer are described in this volume, including macrophage activation therapy, oxidative medicine, lymphokine activated killers, and non-specific immune stimulants. Significant effort was made by the authors to detail how various components of the immune system collaborate in the recognition of cancer cells, how cancer cells avoid immune attack, and means of derepressing immunity using chemical, cellular, and genetic approaches. Specific tumor immune evasion mechanisms that are described include: a) the tryptophan-catabolizing enzyme indolamine 2,3 deoxygenase (IDO), which selectively induces suppression of cytotoxic T cells through anergy, apoptosis, and T regulatory cell generation; b) IL-10, a cytokine produced by tumor cells, as well as tumor-associated macrophages, which induces generation of T regulatory cells; c) cancer derived exosomes, which act as nanoparticle vesicles, that directly induce apoptosis of tumor-reactive T cells, as well as assist in formation of extracellular matrix that is receptive to tumor metastasis; d) soluble HLA-like molecules including MICA, which block the activation of natural killer cells, the cells that are capable of killing tumors which have downregulated antigen presentation; e) arginase, an enzyme produced by M2 macrophages, which produces an immune suppressive localized environment; and f) tumor lactic acid accumulation, which blocks cytotoxic activity of T cells, while at the same time allowing for survival of T regulatory cells, which in turn suppress the immune system. In addition to overviewing how cancer suppresses the immune system, discuss how the immune system suppresses cancer. Detailed descriptions are provided of immune modulators that have demonstrated clinical efficacy signals dating back from the days of Coley's toxins, all the way to the current immune checkpoint inhibitor trials. Specific areas of concentration include: a) cytokine induced killer cells; b) lymphokine activated killers; c) BCG; and d) cancer vaccines. We trust that the current volume will provide its readers not only with details of the immune-tumor interaction, but will also provide solid support for novel experimental approaches to cancer, including combination of T regulatory cell depleting chemotherapies with immunotherapy, as well as combinations of intravenous nutrients with immune stimulators.

American Journal of Respiratory and Critical Care Medicine

American Journal of Respiratory and Critical Care Medicine Book
Author : Anonim
Publisher : Unknown
Release : 2009
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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The Spondylarthritides

The Spondylarthritides Book
Author : Andrei Calin,Joel D. Taurog
Publisher : Oxford University Press, USA
Release : 1998
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The term Spondylarthitides refers to a group of common rheumatic disorders affecting the spine and peripheral joints. The distribution of this disease is world-wide, with both men and women affected (the average age of onset being below 30 years). These also serve as a model system for understanding the interaction between disease-inducing micro-organisms, and genetically-susceptible host, since both of these components are particularly well defined in the spondylarthopathies. They are therefore of great interest from the point of veiw of understanding the pathogenesis of inflammatory and autoimune diseases, such as arthritis, inflammatory bowel disease, and insulin dependent diabetes mellitus, all of which involve an interplay of microbial and genetic factors. The Spondylarthritides provides up to date, in depth reviews of the current state of knowledge of the genetic, epidemiologic, microbiologic, and immunologic aspects of these disorders. The book provides extensive clinical descriptions of the spondylarthritides, as well as reviews of the clinical features of these diseases. Written by an international team comprised of leading authorities in the field, the book will be of considerable interest to researchers and clinicians investigating these specific disorders, as well as related inflammatory disorders.

Inflammatory Bowel Diseases

Inflammatory Bowel Diseases Book
Author : T. Andus
Publisher : Unknown
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Journal of Investigative Medicine

Journal of Investigative Medicine Book
Author : Anonim
Publisher : Unknown
Release : 1996-04
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Immunology of Diabetes V

Immunology of Diabetes V Book
Author : Immunology of Diabetes Society. International Congress
Publisher : Wiley-Blackwell
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This volume an overview of current research in the field of immunology as it relates to diabetes. Topics covered include: autoantibody markers for type 1 diabetes; cellular immune markers for type 1 diabetes; animal models of type 1 diabetes; the pancreas in type 1 diabetes; genetics of type 1 diabetes; the role of toll-like receptors and innate immunity in type 1 diabetes; cell-based therapies for type 1 diabetes; environmental and mechanistic causes of type 1 diabetes; mechanisms of beta-cell death; role of the immune response in type 1 diabetes; and islet transplantation. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/membership/main.asp for more information about becoming a member.

Minor Histocompatibility Antigens

Minor Histocompatibility Antigens Book
Author : Derry Roopenian
Publisher : CRC Press
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

With the widespread application of solid tissue and bone marrow transplantation as a treatment for an array of life threatening disorders, there is a pressing need for clinicians and experimentalists to understand the basis of immunological rejection of tissue transplants. While much previous work focuses on characterization of antigens encoded by the major histocompatibility complex (MHC) in this process, the many histocompatibility (H) antigens encoded outside of the MHC, the so-called minor H antigens, have only recently been identified at the molecular level. This easily readable but comprehensive text is the first to put together insightful historic perspectives with up-to-date advances in the molecular genetics, biochemistry and immunobiology of minor H antigens from both experimental and clinical points of view. In doing so it provides a sourcebook particularly suited for clinicians and experimental immunologists engaged in tissue transplantation. The text recounts the progress being made on many fronts. Newer approaches have extracted molecular explanations finally allowing one to ascribe a rational molecular basis to minor H minor antigens both in rodents and humans. This understanding also paves the way to apply new genomic analyses to the problem of tissue transplantation.