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History Of Modern Clinical Toxicology

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History of Modern Clinical Toxicology

History of Modern Clinical Toxicology Book
Author : Alan Woolf
Publisher : Elsevier
Release : 2021-11-04
ISBN : 0128222182
Language : En, Es, Fr & De

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Book Description :

History of Modern Clinical Toxicology describes the extraordinary advances in the practice of clinical toxicology within the past 70 years and brings together stories of the people - the champions of clinical toxicology - who contributed to these advances, discovered new therapies and antidotes, and made change happen. This book lays out the poison control system they built and the fascinating story of how they created a new and evolving medical specialty. With the participation of renowned international experts as authors, the book showcases the development of poison control centers around the world and the growth of the professional societies that represent and support them today. This book also tells the stories of the modern-day toxic disasters and recent toxic exposures that gained worldwide attention and notoriety. It outlines the public health responses to such calamities which have led to improvements in our understanding of the science and changes in public health policies and regulations to forestall future such events. Finally, the book covers key policies and agencies affecting poison control centers, addresses the challenges facing clinical toxicologists of today, and predicts advances and future innovations in the field. History of Modern Clinical Toxicology is a unique resource that provides the historical and international perspective that will help students, practitioners, scientists, and health policy makers put current issues and methods in perspective. It will help them understand how infrastructure and processes in clinical toxicology have evolved and why poison control systems are configured as they are. Offers descriptions of the key regulatory advances affecting clinical toxicology Provides synopses of modern-day poisoning disasters Outlines the development of modern antidotes and future directions in clinical toxicology Describes the origins and development of the U.S. poison control system Includes the origins and features of professional clinical toxicology societies from around the world Includes descriptions of the history of clinical toxicology and poison control in more than 35 countries

History of Modern Clinical Toxicology

History of Modern Clinical Toxicology Book
Author : Alan Woolf
Publisher : Academic Press
Release : 2021-10-13
ISBN : 0128222190
Language : En, Es, Fr & De

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Book Description :

History of Modern Clinical Toxicology describes the extraordinary advances in the practice of clinical toxicology within the past 70 years and brings together stories of the people – the champions of clinical toxicology - who contributed to these advances, discovered new therapies and antidotes, and made change happen. This book lays out the poison control system they built and the fascinating story of how they created a new and evolving medical specialty. With the participation of renowned international experts as authors, the book showcases the development of poison control centers around the world and the growth of the professional societies that represent and support them today. This book also tells the stories of the modern-day toxic disasters and recent toxic exposures that gained worldwide attention and notoriety. It outlines the public health responses to such calamities which have led to improvements in our understanding of the science and changes in public health policies and regulations to forestall future such events. Finally, the book covers key policies and agencies affecting poison control centers, addresses the challenges facing clinical toxicologists of today, and predicts advances and future innovations in the field. History of Modern Clinical Toxicology is a unique resource that provides the historical and international perspective that will help students, practitioners, scientists, and health policy makers put current issues and methods in perspective. It will help them understand how infrastructure and processes in clinical toxicology have evolved and why poison control systems are configured as they are. Offers descriptions of the key regulatory advances affecting clinical toxicology Provides synopses of modern-day poisoning disasters Outlines the development of modern antidotes and future directions in clinical toxicology Describes the origins and development of the U.S. poison control system Includes the origins and features of professional clinical toxicology societies from around the world Includes descriptions of the history of clinical toxicology and poison control in more than 35 countries

Loomis s Essentials of Toxicology

Loomis s Essentials of Toxicology Book
Author : A. Wallace Hayes,Tao Wang,Darlene Dixon,Ted A. Loomis
Publisher : Academic Press
Release : 2019-10-24
ISBN : 0128159227
Language : En, Es, Fr & De

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Book Description :

Loomis's Essentials of Toxicology, Fifth Edition, provides the information on the harmful biologic effects associated with exposures to chemicals of all types. The scope of this book includes a discussion of the major types of chemicals involved, their general properties and detrimental biologic effects, the methods used to demonstrate these effects, the basis for clinical diagnosis, and therapy for the harmful effects of chemicals on humans. Individual examples are used to demonstrate the principle discussed. This reference volume will be an invaluable resource for both toxicologists and graduate and advanced undergraduate students in toxicology and public health. Provides a revised and updated edition of one of the "gold" works in the field Includes both principles and methods Requires minimal background in chemistry and biology Expanded Information Sources in Toxicology

Forging a Poison Prevention and Control System

Forging a Poison Prevention and Control System Book
Author : Institute of Medicine,Board on Health Promotion and Disease Prevention,Committee on Poison Prevention and Control
Publisher : National Academies Press
Release : 2004-09-16
ISBN : 0309091942
Language : En, Es, Fr & De

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Book Description :

Poisoning is a far more serious health problem in the U.S. than has generally been recognized. It is estimated that more than 4 million poisoning episodes occur annually, with approximately 300,000 cases leading to hospitalization. The field of poison prevention provides some of the most celebrated examples of successful public health interventions, yet surprisingly the current poison control "system" is little more than a loose network of poison control centers, poorly integrated into the larger spheres of public health. To increase their effectiveness, efforts to reduce poisoning need to be linked to a national agenda for public health promotion and injury prevention. Forging a Poison Prevention and Control System recommends a future poison control system with a strong public health infrastructure, a national system of regional poison control centers, federal funding to support core poison control activities, and a national poison information system to track major poisoning epidemics and possible acts of bioterrorism. This framework provides a complete "system" that could offer the best poison prevention and patient care services to meet the needs of the nation in the 21st century.

Modern Medical Toxicology

Modern Medical Toxicology Book
Author : Pillay
Publisher : JAYPEE BROTHERS PUBLISHERS
Release : 2012-11-30
ISBN : 9350259656
Language : En, Es, Fr & De

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Book Description :

Download Modern Medical Toxicology book written by Pillay, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Casarett Doull s Essentials of Toxicology Third Edition

Casarett   Doull s Essentials of Toxicology  Third Edition Book
Author : John B. Watkins, III PhD,Curtis D. Klaassen
Publisher : McGraw-Hill Education / Medical
Release : 2015-08-17
ISBN : 9780071847087
Language : En, Es, Fr & De

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Book Description :

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product.Understand the essential principles of toxicology and how poisons affect the human body with this accessible and engaging summary A Doody's Core Title for 2017! Casarett & Doull’s Essentials of Toxicology is an easy-to-absorb distillation of the major principles and concepts that were presented in depth in Casarett & Doull’s Toxicology: The Basic Science of Poisons, Eighth Edition, the field’s gold-standard text. Presented in full color, the book concisely describes the science of toxicology, and includes important concepts from anatomy, physiology, and biochemistry to facilitate the understanding of the principles and mechanisms of toxicant action on specific organ systems. A summary of key points at the beginning and review questions at the end of each chapter help you study, understand, and memorize the material. Reflecting the expertise of more than sixty renowned contributors, Casarett & Doull’s Essentials of Toxicology is logically divided into seven sections: Succinct and comprehensive, there is no better text for gaining an understanding of essential principles, toxicokinetics, how toxic effects are passed on to succeeding generations, how each body system responds to poisons, and the specific effects of a wide range of toxic agents than Casarett & Doull’s Essentials of Toxicology.

Toxicology

Toxicology Book
Author : John Joseph Fenton
Publisher : CRC Press
Release : 2001-10-10
ISBN : 1420042068
Language : En, Es, Fr & De

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Book Description :

REAL-LIFE CASES, TUTORIAL QUESTIONS, NARRATIVE HISTORY Intriguing anecdotal pedagogy, like the alleged arsenical poisonings of Napoleon and President Taylor and the probable mercury overdose of Isaac Newton, is one of the things that set Toxicology: A Case-Oriented Approach apart from other toxicology texts. Based on an undergraduate-graduate combined toxicology course at West Chester University, this innovative text captures readers' interest by combining modern case studies, historical cases, and hundreds of illustrations and tables. Each chapter presents several case scenarios that involve the reader with questions about diagnosis, testing methods, treatment, and other pertinent information. TOXICOLOGY FOR THE LABORATORY AND THE EMERGENCY ROOM In an easy-to-read style, this book covers the major organ systems and reviews the effects of toxins in each system. Most contemporary books are almost entirely clinical or entirely analytical. Toxicology: A Case-Oriented Approach treats each area extensively to benefit students and professionals who need to know aspects of both. It describes diagnosis and treatment of each specific poisonous exposure and discusses chemical basis and the laboratory testing of toxins. This dual perspective, coupled with the book's interesting narrative approach, lets readers quickly absorb the information they need to understand toxicology in the laboratory and in the Emergency Department.

History of Toxicology and Environmental Health

History of Toxicology and Environmental Health Book
Author : Philip Wexler
Publisher : Academic Press
Release : 2014-09-18
ISBN : 0128016345
Language : En, Es, Fr & De

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Book Description :

This volume, Toxicology in Antiquity II, continues to tell the story of the roots of toxicology in ancient times. Readers learn that before scientific research methods were developed, toxicology thrived as a very practical discipline. Toxicologists are particularly proud of the rich and storied history of their field and there are few resources available that cover the discipline from a historical perspective. People living in ancient civilizations readily learned to distinguish safe from hazardous substances, how to avoid these hazardous substances and how to use them to inflict harm on enemies. Volume II explores the use of poison as weapons in war and assassinations, early instances of air pollution, the use of hallucinogens and entheogens, and the role of the snake in ancient toxicology. Provides the historical background for understanding modern toxicology Illustrates the ways ancient civilizations learned to distinguish safe from hazardous substances, how to avoid the hazardous substances and how to use them against enemies Details scholars who compiled compendia of toxic agents

The Law of Off label Uses of Medicines

The Law of Off label Uses of Medicines Book
Author : Andrea Parziale
Publisher : Taylor & Francis
Release : 2022-08-12
ISBN : 1000634388
Language : En, Es, Fr & De

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Book Description :

This book examines the regulatory framework for untested and unapproved uses (off-label uses) of medicines in the EU, UK, and USA. Before reaching patients, medicines are extensively tested by manufacturers and approved by regulators to minimise the risk of adverse reactions. However, physicians can prescribe pharmaceuticals for off-label uses, widespread in paediatrics, oncology, rare diseases and, more recently, in treatment for Covid-19. While off-label uses may offer hope, they may also expose patients to risks and uncertainties. Clarification is therefore needed to improve the protection of patients' rights while enhancing legal certainty for health actors. To this end, this work clarifies the regulatory mechanisms and litigation trends concerning off-licence prescriptions in these jurisdictions. It assesses how traditional, prevention-driven regulatory and civil liability rules are being adapted to tackle potential risks and scientific uncertainty. The book outlines the applicable regulations, as well as considering Brexit’s impact on off-label policies in the UK, and EU and national off-label policies in the context of the fight against the Covid-19 pandemic. It also explores under what conditions physicians, manufacturers, or regulators must compensate patients injured by untested prescriptions. The book will be an essential resource for researchers, academics and policy-makers working in the areas of medical law and ethics, public health law, pharmaceutical law and private comparative law.

A Textbook of Modern Toxicology

A Textbook of Modern Toxicology Book
Author : Ernest Hodgson
Publisher : John Wiley & Sons
Release : 2011-09-20
ISBN : 1118211294
Language : En, Es, Fr & De

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Book Description :

A Textbook of Modern Toxicology is a unique resource thatprovides both students and practitioners with a wide-ranging,accessible overview of the discipline. Suitable for courses inenvironmental, pharmacological, medical, and veterinary toxicology,this essential text features chapters written by experts whoaddress a range of key topics. The Fourth Edition includes additional chapters on newapproaches to toxicology - molecular methods (-omics:toxicogenomics, proteomics, and metabolomics), bioinformatics, andsystems biology – and continues the legacy of itspredecessors to provide up-to-date insights into acute toxicity andchemical carcinogenesis, organ toxicity, in vitro and in vivotoxicity testing, ecological risk assessment, and many other areasof toxicology that help foster a solid comprehension of thefield. Also featured in the Fourth Edition are end-of-chapter questionsand a Solutions Manual available separately for academicadopters.

Information Resources in Toxicology

Information Resources in Toxicology Book
Author : Steve Gilbert,Asish Mohapatra,Sol Bobst,Antoinette Hayes,Sara T. Humes
Publisher : Academic Press
Release : 2020-05-15
ISBN : 0128216123
Language : En, Es, Fr & De

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Book Description :

This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology’s subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools. Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology’s presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field. The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children’s environmental health. Opens with an overview of the international toxicology scene, organizations and activities involved with both the science and regulatory framework, and a specific look at the European Union’s efforts. Offers an extensive collection of chapters covering over 40 countries and their toxicological infrastructure which includes listings of major books and journals, organizations, professional societies, universities, poison control centers, legislation, and online databases. Provides the Second Edition of the International Union of Pure and Applied Chemistry’s Glossary of Terms Used in Toxicology, a carefully constructed and peer reviewed collation of critical terms in the science. Concludes with a potpourri of quotes concerning toxicology and their use in the arts and popular culture. Paired with Volume One, which offers chapters on a host of toxicology sub-disciplines, this set offers the most comprehensive compendium of print, digital, and organizational resources in the toxicological sciences with over120 chapters contributions by experts and leaders in the field.

P5 Medicine and Justice

P5 Medicine and Justice Book
Author : Santo Davide Ferrara
Publisher : Springer
Release : 2018-03-27
ISBN : 3319670921
Language : En, Es, Fr & De

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Book Description :

This book describes the state of the art and future prospects of the most important bio-medicolegal subdisciplines in the post-genomic framework of personalized medicine. Focusing on the three main themes Innovation, Unitariness and Evidence, the book addresses a wide range of topics, including: Bio-Medicolegal and Criminological Sciences, Forensic Pathology and Anthropology, Clinical and Forensic Medicine in Living Persons (from Interpersonal Violence to Personal Injury and Damage, Malpractice, Personal Identification and Age Estimation), Forensic Genetics and Genomics, and Toxicology and Imaging. The unitariness of the “Bio-Medicolegal Sciences”, historically founded on the accuracy and rigor of the methods of ascertainment and criteria of evaluation, should be re-established on the basis of molecular evidence, and used to promote Personalized Justice. Taken together, the book’s conclusions and future perspectives outline a vision of transdisciplinary innovation and future evidence in the framework of personalized justice.

History of Risk Assessment in Toxicology

History of Risk Assessment in Toxicology Book
Author : Sol Bobst
Publisher : Academic Press
Release : 2017-09-20
ISBN : 0128095431
Language : En, Es, Fr & De

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Book Description :

History of Risk Assessment in Toxicology guides the reader through the historical narrative of the evolution of risk assessment thinking in human and environmental practices. Risk assessment concepts are used in many different professional practice areas. In the health and environmental practices of risk assessment, the critical issue is often what chemical concentration in air, water, food, or a solid substance is acceptable, or considered not to result in any adverse effect. The book reviews examples from early scientific and health studies to showcase the foundations of risk assessment. The book also explores the development of risk assessment as practiced by major regulatory bodies such as the US Food and Drug Administration (FDA), the Occupational Safety & Health Administration (OSHA), and the US Environmental Protection Agency (EPA) to reveal how risk assessment has evolved in the 20th and 21st centuries. Modern technology has created opportunities in silicon in vitro, computational modeling, omics, and big data techniques to assess the toxicity of chemicals, while traditional approaches to risk assessment are being challenged with new and innovative approaches. Finally, current issues being debated and tested in risk assessment are outlined with possible future avenues suggested. Presents the first dedicated history on the evolution of risk assessment in toxicology Reviews the development of major US and EU regulatory bodies Provides a context to current debates surrounding the future of risk assessment Reviews examples from early scientific and health studies to showcase the foundations of risk assessment

Toxicology in the Middle Ages and Renaissance

Toxicology in the Middle Ages and Renaissance Book
Author : Philip Wexler
Publisher : Academic Press
Release : 2017-03-13
ISBN : 0128095598
Language : En, Es, Fr & De

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Book Description :

Toxicology in the Middle Ages and Renaissance provides an authoritative and fascinating exploration into the use of toxins and poisons in the Middle Ages and Renaissance. Part of the History of Toxicology and Environmental Health series, this volume is a follow-up, chronologically, to the first two volumes which explored toxicology in antiquity. The book approximately covers the 1100s through the 1600s, delving into different aspects of toxicology, such as the contributions of scientific scholars of the time, sensational poisoners and poisoning cases, as well as myths. Historical figures, such as the Borgias and Catherine de Medici are discussed. Toxicologists, students, medical researchers, and those interested in the history of science will find insightful and relevant material in this volume. Provides the historical background for understanding modern toxicology Illustrates the ways previous civilizations learned to distinguish safe from hazardous substances, how to avoid them, and how to use them against enemies Explores the way famous historical figures used toxins

Toxicological Risk Assessment and Multi System Health Impacts from Exposure

Toxicological Risk Assessment and Multi System Health Impacts from Exposure Book
Author : Aristidis M. Tsatsakis
Publisher : Elsevier
Release : 2021-08-01
ISBN : 0323853587
Language : En, Es, Fr & De

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Book Description :

Toxicological Risk Assessment and Multisystem Health Impacts From Exposure highlights the emerging problems of human and environmental health attributable to cumulative and multiple sources of long-term exposure to environmental toxicants. The book describes the cellular, biological, immunological, endocrinologic, genetic, and epigenetic effects of long-term exposure. It examines how the combined exposure to nanomaterials, metals, pharmaceuticals, multifrequency radiation, dietary mycotoxins, and pesticides accelerates ecotoxicity in humans, animals, plants, and the larger environment. The book goes on to also offer insights into mixture risk assessments, protocols for evaluating the risks, and how this information can serve the regulatory agencies in setting safer exposure limits. The book is a go-to resource for scientists and professionals in the field tackling the current and emerging trends in modern toxicology and risk assessment. • Bridges basic research with clinical, epidemiological, regulatory, and translational research, conveying both an introductory understanding and the latest developments in the field • Evaluates real-life human health risk assessment for long-term exposures to xenobiotic mixtures and the role they play in contributing to chronic disease • Discusses advances in predictive (in silico) toxicology tools and the benefits of using omics technologies in toxicology research

A Textbook of Modern Toxicology

A Textbook of Modern Toxicology Book
Author : Ernest Hodgson,Patricia E. Levi
Publisher : McGraw-Hill Medical Publishing
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This revised edition reflects changes in the core curriculum subjects covered in the basic toxicology course for graduate students. Designed as an introductory textbook, it emphasizes the fundamental basis of toxic action at the cellular and molecular levels and lays the foundation for specialized courses in toxicology. Additional topics include metabolic activation and cellular protection, clinical toxicology diagnosis and treatment, ecosystems, environmental toxicology, ecotoxicology, case histories, and future consideration for environmental and human health.

Fundamentals Of Aquatic Toxicology

Fundamentals Of Aquatic Toxicology Book
Author : Gary M. Rand
Publisher : CRC Press
Release : 1995-10-05
ISBN : 9781560320906
Language : En, Es, Fr & De

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Book Description :

This text is divided into three parts. The first part describes basic toxicological concepts and methodologies used in aquatic toxicity testing, including the philosophies underlying testing strategies now required to meet and support regulatory standards. The second part of the book discusses various factors that affect transport, transformation, ultimate distribution, and accumulation of chemicals in the aquatic environment, along with the use of modelling to predict fate.; The final section of the book reviews types of effects or endpoints evaluated in field studies and the use of structure-activity relationships in aquatic toxicology to predict biological activity and physio-chemical properties of a chemical. This section also contains an extensive background of environmental legislation in the USA and within the European Community, and an introduction to hazard/risk assessment with case studies.

Poisoning in the Modern World

Poisoning in the Modern World Book
Author : Ozgur Karcioglu,Banu Arslan
Publisher : BoD – Books on Demand
Release : 2019-06-19
ISBN : 1838807853
Language : En, Es, Fr & De

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Book Description :

Over 400 years ago, Swiss alchemist and physician Paracelsus (1493-1541) cited: "All substances are poisons; there is none that is not a poison. The right dose differentiates a poison from a remedy." This is often condensed to: "The dose makes the poison." So, why are we overtly anxious about intoxications?In fact, poisons became a global problem with the industrial revolution. Pesticides, asbestos, occupational chemicals, air pollution, and heavy metal toxicity maintain high priority worldwide, especially in developing countries. Children between 0 and 5 years old are the most vulnerable to both acute and chronic poisonings, while older adults suffer from the chronic effects of chemicals. This book aims to raise awareness about the challenges of poisons, to help clinicians understand current issues in toxicology.

Clinical Toxicology An Issue of Emergency Medicine Clinics of North America E Book

Clinical Toxicology  An Issue of Emergency Medicine Clinics of North America  E Book Book
Author : Daniel M Lugassy
Publisher : Elsevier Health Sciences
Release : 2014-02-09
ISBN : 032326655X
Language : En, Es, Fr & De

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Book Description :

This issue of Emergency Medicine Clinics focuses on Clinical Toxicology and is edited by Drs. Daniel Lugassy and Silas Smith and includes such topics as Emerging Drugs of Abuse, Pediatric Toxicology; Dosing and Medical Errors and Child Abuse,The Approach to Toxin-Induced Coagulopathy,The Approach to Toxin-Induced Cardiovascular Failure, The Approach to Toxin-Induced Metabolic Acidosis, The Approach to Withdrawal Syndromes, The Approach to Radiation Exposure, and more.

Basic and Clinical Toxicology of Mustard Compounds

Basic and Clinical Toxicology of Mustard Compounds Book
Author : Mahdi Balali-Mood,Mohammad Abdollahi
Publisher : Springer
Release : 2015-12-01
ISBN : 3319238744
Language : En, Es, Fr & De

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Book Description :

This book offers a practical guide to the clinical management of sulphur and nitrogen mustard exposure including information on the history, pharmacology and toxicology of mustard compounds (MC). Basic and Clinical Toxicology of Mustard Compounds details the many resulting complications of sulphur mustard (SM) poisoning such as respiratory, Dermatological, Ophthalmological and Psychiatric. This volume is a key resource for clinical toxicologists, military and emergency physicians who are involved in the teaching and research of MC and for all medical and health professions who are responsible for the prevention, diagnosis and treatment of MC poisonings.