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Hepatitis C In Developing Countries

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Hepatitis C in Developing Countries

Hepatitis C in Developing Countries Book
Author : Sanaa M. Kamal
Publisher : Academic Press
Release : 2017-11-23
ISBN : 0128032340
Language : En, Es, Fr & De

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Book Description :

Hepatitis C in Developing Countries: Current and Future Challenges explores the current state of HCV in several countries, including Africa, Asia and South America. It maintains a dedicated focus on the epidemiology, clinical patterns, virologic diversity, coinfections, natural history and progression, complications, and response to standard of care (SOC) pegylated interferon and ribavirin therapy of HCV with recommendations specific to middle and low income countries. Readers will find detailed information on the burden of HCV infection from a global health and economic perspective, along with data from multicenter trials on DAAs that have enrolled patients infected with HCV non-genotype 1. Features coverage on the prevention of, or inhibition of, liver fibrosis, cirrhosis, and hepatocellular carcinoma Presents data from trials on patients with diverse ethnic backgrounds and those infected with genotypes 3, 4, 5, 6 Addresses the epidemiology, modes of transmission, socio-political aspects, genotypes, and co-infections of Hepatitis C

Current Progress and Challenges in the Development of a Hepatitis C Virus Vaccine

Current Progress and Challenges in the Development of a Hepatitis C Virus Vaccine Book
Author : Steven K.H. Foung,Thomas F. Baumert
Publisher : Frontiers Media SA
Release : 2019-01-22
ISBN : 2889457141
Language : En, Es, Fr & De

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Book Description :

More than 70 million people worldwide are infected with hepatitis C virus, a major cause of liver cirrhosis, liver failure and hepatocellular carcinoma world-wide. In the last decade, this cancer has emerged as the second leading cause of cancer death and the global burden is increasing by two million new infections per year, mainly due to injection drug use. An effective vaccine will be the most effective means to contain the spread of this virus worldwide. The articles in this Research Topic describe the progress that has been made towards a preventive vaccine and the challenges that still need to be overcome to ultimately achieve this goal.

Hepatitis C Host and Viral Factors Associated with Response to Therapy and Progression of Liver Fibrosis

Hepatitis C  Host and Viral Factors Associated with Response to Therapy and Progression of Liver Fibrosis Book
Author : Snezana Jovanovic-Cupic
Publisher :
Release : 2018
ISBN :
Language : En, Es, Fr & De

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Book Description :

The goal of this study was to identify the baseline host and viral factors of response to antiviral therapy in patients with chronic hepatitis C. Compared with interferon/ribavirin therapy, new current direct-acting antiviral (DAA) combination regimens significantly increased rate of sustained virologic response (SVR) and shorter treatment durations, but is still limited by viral resistance, adverse effects, and high cost especially in developing countries. Human genetic factors and heterogeneity within the HCV genome may be associated with virologic treatment failure before and after antiviral therapy. Further, HCV infection may contribute to the development of HCV-related liver disease and hepatocarcinogenesis, through modulating genetic and epigenetic state of certain genes implicated in control of critical cellular pathways. Previous results confirm the importance of host and viral factors and virus-induced genetic and epigenetic changes in predicting outcome and treatment response.

Diabetes Mellitus in Developing Countries and Underserved Communities

Diabetes Mellitus in Developing Countries and Underserved Communities Book
Author : Sam Dagogo-Jack
Publisher : Springer
Release : 2016-11-23
ISBN : 331941559X
Language : En, Es, Fr & De

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Book Description :

Adopting a truly global perspective and a practical approach to diabetes—including pathophysiology, genetics, regional peculiarities, management, prevention and best practices—this book is an excellent resource for clinicians and policy-makers working with patients in more austere settings. The global prevalence of diabetes is estimated to increase from 422 million in 2014 to 592 million in 2035. Sadly, low- and middle-economy countries are projected to experience the steepest increase, but even in developed economies, vulnerable demographic subgroups manifest disparities in diabetes prevalence, quality of care, and outcomes. This book extends coverage to those underserved and minority communities in the developed world. In a consistent chapter format, it discusses classification, pathophysiology, genomics, diagnosis, prevention and management of diabetes in economically challenged regions as well as underserved populations in affluent nations. Suggestions regarding future directions in the organization of diabetes care delivery, prevention and research priorities are also provided. The detailed identification of barriers to optimal care and the practical approach to the management and prevention of diabetes make Diabetes Mellitus in Developing Countries and Underserved Communities a valuable resource for clinicians, researchers and health policy leaders.

Disease Control Priorities in Developing Countries

Disease Control Priorities in Developing Countries Book
Author : Dean T. Jamison,Joel G. Breman,Anthony R. Measham,George Alleyne,Mariam Claeson,David B. Evans,Prabhat Jha,Anne Mills,Philip Musgrove
Publisher : World Bank Publications
Release : 2006-04-02
ISBN : 0821361805
Language : En, Es, Fr & De

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Book Description :

Based on careful analysis of burden of disease and the costs ofinterventions, this second edition of 'Disease Control Priorities in Developing Countries, 2nd edition' highlights achievable priorities; measures progresstoward providing efficient, equitable care; promotes cost-effectiveinterventions to targeted populations; and encourages integrated effortsto optimize health. Nearly 500 experts - scientists, epidemiologists, health economists,academicians, and public health practitioners - from around the worldcontributed to the data sources and methodologies, and identifiedchallenges and priorities, resulting in this integrated, comprehensivereference volume on the state of health in developing countries.

Hepatitis C

Hepatitis C Book
Author : Andrea D. Branch,Charles L. Branch, Jr.,Leonard B. Seeff
Publisher : Thieme
Release : 2000
ISBN : 9780865779983
Language : En, Es, Fr & De

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Book Description :

A timely collection of scientific & clinical information on Hepatitis C. A bound compilation of issues 1 and 2 of Seminars in Liver Disease, 2000. A hardbound compendium of Volume 20, Numbers 1 and 2 of the journal, Seminars in Liver Disease, this new volume brings together an international group of distinguished authors to present 16 current, incisive reviews and analyses of both the basic science and clinical aspects of HCV. The volume examines the broadest spectrum of HCV virology, pathology, and disease while focusing on the following key issues: HCV's impact on human populations The manifestations of the virus & its distribution throughout the body HCV molecular virology with an emphasis on its clinical implications Identification of pharmaceutical targets and vaccine components and an analysis of genotypes and interferon sensitivity In addition, the volume examines the clinical consequences of HCV infection, including immune response to HCV, B-cell abnormalities, diagnostic tests, kinetic studies, interferon-ribavirin combination therapy, liver transplantation, and vaccine development.

Health Care Associated Transmission of Hepatitis B and C Viruses An Issue of Clinics in Liver Disease E Book

Health Care Associated Transmission of Hepatitis B and C Viruses  An Issue of Clinics in Liver Disease   E Book Book
Author : Bandar Al Knawy
Publisher : Elsevier Health Sciences
Release : 2010-02-25
ISBN : 1455700401
Language : En, Es, Fr & De

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Book Description :

This issue offers the latest information regarding the transmission of hepatitis viruses in various healthcare settings. It delves with a very timely and interesting patient safety subject that specifically targets healthcare professionals, gastroenterologists, hepatologists, oncologists, dentists and all healthcare workers to adopt and share a variety of best practices to prevent this adverse event. Well known faculty in liver disease, infection control as well as a medical practice in a legal setting have been assembled to produce a comprehensive and concise edition that highlights the latest information regarding hepatitis B and C transmission in healthcare. It aims to provide an overview on the molecular epidemiology, the outbreak reports, the transmission in hemodialysis, endoscopy, dental, oncology, management, legal aspects and the infection prevention measures to reduce the risk of needless exposure of patients to these blood borne pathogens.

Public Health and Infectious Diseases

Public Health and Infectious Diseases Book
Author : Jeffrey Griffiths,James H. Maguire,Kristian Heggenhougen,Stella R. Quah
Publisher : Elsevier
Release : 2010-03-09
ISBN : 012381507X
Language : En, Es, Fr & De

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Book Description :

Emerging infectious diseases may be defined as diseases being caused by pathogens only recently recognized to exist. This group of diseases is important globally, and the experience of the last 30 years suggests that new emerging diseases are likely to bedevil us. As the global climate changes, so changes the environment, which can support not only the pathogens, but also their vectors of transmission. This expands the exposure and effects of infectious disease and, therefore, the importance of widespread understanding of the relationship between public health and infectious disease. This work brings together chapters that explain reasons for the emergence of these infectious diseases. These include the ecological context of human interactions with other humans, with animals that may host human pathogens, and with a changing agricultural and industrial environment, increasing resistance to antimicrobials, the ubiquity of global travel, and international commerce. * Features the latest discoveries related to influenza with a newly published article by Davidson Hamer and Jean van Seventer * Provides a listing of rare diseases that have become resurgent or spread their geographic distribution and are re-emergent * Highlights dengue and malaria, as well as agents such as West Nile and other arboviruses that have spread to new continents causing widespread concerns * Includes discussions of climate influencing the spread of infectious disease and political and societal aspects

HCV and Related Liver Diseases

HCV and Related Liver Diseases Book
Author : Kiwamu Okita
Publisher : Springer
Release : 2012-02-29
ISBN : 9784431684909
Language : En, Es, Fr & De

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Book Description :

More than 2 million people in Japan have chronic hepatitis C and many of them will lose their lives to liver cirrhosis or complications of hepatocellular carcinoma. Hepatitis C virus-related diseases are a serious concern both in developing countries and in Japan and the United States, where the number of patients is also in the millions. Therapeutic modalities recently developed in Japan, including interferon therapy and nutritional supportive therapy, are gaining worldwide acceptance. At this critical juncture, HCV and Related Liver Diseases presents new information on etiology, pathology, diagnosis, and therapy. Viral hepatitis was the theme of the Yamaguchi Symposium on Liver Disease, meeting in December 1998 and attended by leading hepatologists and virologists. Collected in this volume are the papers from the symposium, providing a valuable resource for hepatologists, gastroenterologists, and others working to understand and treat viral hepatitis.

Viral Hepatitis

Viral Hepatitis Book
Author : Howard C. Thomas,Anna S. F. Lok,Stephen A. Locarnini,Arie J. Zuckerman
Publisher : John Wiley & Sons
Release : 2013-07-22
ISBN : 111863733X
Language : En, Es, Fr & De

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Book Description :

The 4th edition of Viral Hepatitis coverscomprehensively the entire complex field of infections caused byall of the different hepatitis viruses, which affect many millionsof people throughout the world with considerable morbidity andmortality. Howard Thomas and Arie Zuckerman are joined by Anna Lok from theUSA and Stephen Locarnini from Australia as Editors. Theyhave recruited leading researchers and physicians from manycountries, who have produced an authoritative account of currentknowledge and research on this important infection, including newinsights into immune response to HBV and HCV. The result is a comprehensive account on all aspects of viralhepatitis, including rapid advances in the diagnosis, management,treatment and prevention of a complex infection, which in the caseof hepatitis B, C and D may lead to severe complications includingchronic hepatitis, cirrhosis and hepatocellular carcinoma. The latest edition of Viral Hepatitis offers an essentialresource of current information for hepatologists,gastroenterologists, infectious diseases specialists and otherclinicians, researchers, public health physicians and National andInternational Health Authorities.

Selected Topics in Obstetrics and Gynaecology 3 For Postgraudate and Practitioners

Selected Topics in Obstetrics and Gynaecology 3  For Postgraudate and Practitioners Book
Author : Shirish N Daftary
Publisher : BI Publications Pvt Ltd
Release : 2007
ISBN : 9788172252496
Language : En, Es, Fr & De

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Book Description :

This is the third issue of the popular series Selected Topics in Obstetrics and Gynaecology. The objective of the series is to present updates and reviews of the current trends in selected and emerging areas of obstetrics and gynaecology, including Indian experience in the subject under review.Selection of topics provides a focus on a range of interesting subjects in a stimulating and concise manner. These review articles are aimed at providing quick updates on the subjects to equip the postgraduate students with contemporary knowledge, and to help practitioners to adopt the recent trends in patient care.

Handbook of Pediatric Transfusion Medicine

Handbook of Pediatric Transfusion Medicine Book
Author : Christopher D. Hillyer,Christopher Hillyer,Ronald Strauss,Naomi Luban
Publisher : Elsevier
Release : 2004-02-23
ISBN : 9780080491431
Language : En, Es, Fr & De

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Book Description :

Structured to be a companion to the recently published Handbook of Transfusion Medicine, the Handbook of Pediatric Transfusion Medicine is dedicated to pediatric hematology-oncology and transfusion medicine, a field which remains ambiguous and which has generated few comprehensive texts. This book stands alone as one of the few texts that addresses transfusion issues specific to pediatric medicine. Written in an eminently readable style, this authoritative handbook is a requirement for any pediatric physician or caregiver. Neonatal and fetal immune response and in utero development issues Blood compatability and pre-transfusion testing issues specific to pediatric and neonatal transfusion Therapeutic apheresis including red blood cell exchange and prophylactic chronic erythrocytapheresis for sickle cell patients Also includes a section that concentrates on the consent, quality and legal issues of blood transfusion and donation

Reverse Genetics of RNA Viruses

Reverse Genetics of RNA Viruses Book
Author : Anne Bridgen
Publisher : John Wiley & Sons
Release : 2012-10-07
ISBN : 111840534X
Language : En, Es, Fr & De

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Book Description :

Reverse genetics, the genetic manipulation of RNA viruses to create a wild-type or modified virus, has led to important advances in our understanding of viral gene function and interaction with host cells. Since many severe viral human and animal pathogens are RNA viruses, including those responsible for polio, measles, rotaviral diarrhoea and influenza infections, it is also an extremely powerful technique with important potential application for the prevention and control of a range of human and animal viral diseases. Reverse Genetics of RNA Viruses provides a comprehensive account of the very latest developments in reverse genetics of RNA viruses through a wide range of applications within each of the core virus groups including; positive sense, negative sense and double stranded RNA viruses. Written by a team of international experts in the field, it provides a unique insight into how the field has developed, what problems are being addressed now and where applications may lead in the future. It will prove invaluable to bioscience, medical and veterinary students, those starting research in this area as well as other researchers and teachers needing to update their knowledge of this fast-moving field. An authoritative, comprehensive overview of reverse genetics in RNA Viruses. Includes numerous examples of cutting- edge applications of reverse genetics within each of the RNA viral groups. Written by a team of international experts, including some of the leading researchers in the field.

Practical Guide to High Risk Pregnancy and Delivery E Book

Practical Guide to High Risk Pregnancy and Delivery   E Book Book
Author : Fernando Arias,Amarnath G Bhide,Arulkumaran S,Kaizad Damania,Shirish N Daftary
Publisher : Elsevier Health Sciences
Release : 2012-05-14
ISBN : 8131231631
Language : En, Es, Fr & De

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Book Description :

The third edition of the book, Practical Guide to High-Risk Pregnancy and Delivery, has been completely revised to present more up-to-date approach to the field. Several changes have been made in the book to keep up with multiple new developments and to facilitate the finding of information. However, the purpose of the book remains unchanged: to provide residents in Obstetrics and Gynecology, fellows in Maternal–Fetal Medicine, obstetricians, general physicians, and interested nurses and medical students with a source of practical information about complications of pregnancy. The book is organized into three sections: Fetal Medicine, Obstetrical Complications and Tropical Diseases in Pregnancy All chapters have been rearranged, expanded, and updated Several new flowcharts, tables, and boxes have been included to make the coverage more comprehensive and contemporary Important points at the end of every chapter help in quick recapitulation. Separate chapters on Hypertensive Disorders in Pregnancy, Diabetes and Pregnancy, and Cardiac Diseases in Pregnancy.

Netter s Infectious Diseases E Book

Netter s Infectious Diseases E Book Book
Author : Elaine C. Jong,Dennis L. Stevens
Publisher : Elsevier Health Sciences
Release : 2011-09-09
ISBN : 1455712256
Language : En, Es, Fr & De

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Book Description :

Netter’s Infectious Diseases provides a comprehensive yet concise overview of current global infectious disease concerns. Elaine Jong and Dennis Stevens cover the basics of the field using beautiful Netter illustrations and accessible "need to know" information on major conditions and problems— including multi-drug-resistance, Staph infections, Chagas disease, and the flu. In print and online, it’s a great tool for quick review or for sharing with patients and staff. Review the basics of infectious disease through comprehensive coverage contained in a single volume reference. Apply "need to know" information from the uniformly concise text and instructive Netter paintings. View detailed Netter illustrations that provide a quick and memorable overview of microbiology, pathophysiology, and clinical presentation. Stay current on modern infectious disease concerns—such as multi-drug-resistant tuberculosis, Staph aureus, Chagas disease, and the flu—with new illustrations in the Netter tradition specifically created to address new topics. Access a companion website at www.netterreference.com featuring the complete searchable text, an Image Bank containing all of the book’s illustrations...downloadable for your personal use, plus 25 printable patient education brochures.

Sheehy s Emergency Nursing E Book

Sheehy s Emergency Nursing   E Book Book
Author : Emergency Nurses Association,ENA
Publisher : Elsevier Health Sciences
Release : 2009-06-30
ISBN : 0323074022
Language : En, Es, Fr & De

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Book Description :

Written by emergency nurses for emergency nurses, this comprehensive, evidence-based resource covers the issues and procedures that are often unique to the emergency department. New developments and changes in clinical practice are incorporated throughout. The user-friendly format features more than 350 high-quality illustrations and 150 tables that highlight essential concepts and offer quick access to vital information. Key coverage includes clinical fundamentals, treatment for trauma and medical-surgical emergencies, the foundations of emergency nursing practice, and special populations. 58 contributors offer valuable insights from a broad range of clinical positions in rural, suburban, and urban areas. High-quality radiographs and other diagnostic images help you learn to identify common conditions — especially head trauma, fractures, and dislocations. Logically organized, chapters are grouped into six sections for quick access to important content: Foundations of Emergency Nursing, Professional Practice, Clinical Foundations of Emergency Nursing, Major Trauma Emergencies, Medical and Surgical Emergencies, and Special Patient Populations. Tables and boxes highlight and summarize critical information for at-a-glance reference. A separate unit on special patient populations covers topics such as child abuse, elder abuse, intimate partner violence, sexual assault, substance abuse and behavioral/pediatric/obstetrical emergencies. Priority nursing diagnoses are highlighted in a quick-reference appendix to help you focus on the most serious problems. Five new chapters bring you the most reliable, up-to-date information on these key topics: Management of the Critical Care Patient in the Emergency Department Family Presence During Resuscitation Forensic Nursing Nuclear, Biological, and Chemical Agents of Mass Destruction Influenza: Seasonal, Avian, and Pandemic Expanded coverage of shock and sepsis provides essential information on pathophysiology and diagnosis, with valuable guidelines for managing these patients. A detailed discussion of various types of triage systems and triage acuity ratings examines valid and reliable methods for differentiating between patients who require immediate treatment and those who can wait. Additional coverage of behavioral health emergencies includes new information on agitation, substance abuse, and suicide prevention.

Tropical Infectious Diseases Principles Pathogens and Practice E Book

Tropical Infectious Diseases  Principles  Pathogens and Practice E Book Book
Author : Richard L. Guerrant,David H. Walker,Peter F. Weller
Publisher : Elsevier Health Sciences
Release : 2011-04-05
ISBN : 1437737773
Language : En, Es, Fr & De

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Book Description :

Tropical Infectious Diseases: Principles, Pathogens and Practice, by Drs. Richard L. Guerrant, David H. Walker, and Peter F. Weller, delivers the expert, encyclopedic guidance you need to overcome the toughest clinical challenges in diagnosing and treating diseases caused by infectious agents from tropical regions. Sweeping updates to this 3rd edition include vaccines, SARS, hepatitis A-E, Crimean-Congo hemorrhagic fever virus, tick-borne encephalitis and Omsk hemorrhagic fever, human papilloma virus, and mucormycosis. New full-color images throughout allow you to more accurately view the clinical manifestations of each disease and better visualize the life cycles of infectious agents. Definitive, state-of-the-art coverage of pathophysiology as well as clinical management makes this the reference you’ll want to consult whenever you are confronted with tropical infections, whether familiar or unfamiliar! Obtain complete and trustworthy advice from hundreds of the leading experts on tropical diseases worldwide, including cutting-edge summaries of pathophysiology and epidemiology as well as clinical management. Get the latest answers on vaccines, SARS, hepatitis A-E, Crimean-Congo hemorrhagic fever virus, tick-borne encephalitis and Omsk hemorrhagic fever, human papilloma virus, mucormycosis, and much more. Implement best practices from all over the world with guidance from almost twice as many international authors - over 100 representing more than 35 countries. Accurately view the clinical manifestations of each disease and visualize the life cycles of infectious agents with new full-color images throughout.

Frontiers in Viral Hepatitis

Frontiers in Viral Hepatitis Book
Author : R.F. Schinazi,J.-P. Sommadossi,C. Rice
Publisher : Elsevier
Release : 2003-12-26
ISBN : 9780444509864
Language : En, Es, Fr & De

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Book Description :

Frontiers in Viral Hepatitis provides a compilation of the research from over 40 key opinion leaders in the field of Hepatitis. The book focuses on the latest advances in the search for new, more effective therapeutic options and related topics in viral hepatitis. These include regulatory issues, epidemiology, and emerging viruses; immunology and vaccines; viral hepatitis B and C infections in children; genetics pathology and viral diagnosis; cell systems and animal models; novel therapeutics for hepatitis B and C; resistance and therapeutic strategies in humans; and prevention and treatment options for hepatocellular carcinoma. The breadth of information published in this volume provides insight into current prevention and treatment options. Recent advances in our understanding of the molecular biology, immunology and pathogenesis of hepatitis viruses have accelerated at a remarkable rate, offering a more comprehensive perspective on hepatitis.