Skip to main content

Helicases From All Domains Of Life

In Order to Read Online or Download Helicases From All Domains Of Life Full eBooks in PDF, EPUB, Tuebl and Mobi you need to create a Free account. Get any books you like and read everywhere you want. Fast Download Speed ~ Commercial & Ad Free. We cannot guarantee that every book is in the library!

Helicases from All Domains of Life

Helicases from All Domains of Life Book
Author : Renu Tuteja
Publisher : Academic Press
Release : 2018-09-21
ISBN : 0128146869
Language : En, Es, Fr & De

GET BOOK

Book Description :

Helicases from All Domains of Life is the first book to compile information about helicases from many different organisms in a single volume. Research in the helicase field has been going on for a long time now, but the completion of so many genomes of these ubiquitous enzymes has made it difficult to keep up with new discoveries. As the huge number of identified DNA and RNA helicases, along with the structural and functional differences among them, make it difficult for the interested scholar to grasp a comprehensive view of the field, this book helps fill in the gaps. Presents updates on the functions and features of helicases across the different kingdoms Begins with a chapter on the evolutionary history of helicases Contains specific chapters on selected helicases of great importance from a biological/applicative point-of-view

Molecular Insights Into the Roles of RNA Helicases During Large Ribosomal Subunit Assembly

Molecular Insights Into the Roles of RNA Helicases During Large Ribosomal Subunit Assembly Book
Author : Gerald Ryan Aquino
Publisher : Unknown
Release : 2021
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

RNA helicases are enzymes present in all domains of life that are important in many aspects of RNA metabolism. They harbor a conserved helicase core that uses the energy of NTP binding and hydrolysis to change affinity to RNA, a biochemical property that provides RNA helicases mechanisms to unwind RNA duplexes. In the last years, there have been multiple lines of evidence that these specialized proteins can also displace proteins bound to RNAs and act as placeholders to promote intermediate RNA structures and folding. These RNA and ribonucleoprotein complex (RNP) remodeling functions underl...

The DNA Replication Machinery as Therapeutic Targets

The DNA Replication Machinery as Therapeutic Targets Book
Author : Andrew F. Gardner,Zvi Kelman
Publisher : Frontiers Media SA
Release : 2019-09-19
ISBN : 2889459276
Language : En, Es, Fr & De

GET BOOK

Book Description :

In all organisms, the DNA replication machinery is responsible for accurate and efficient duplication of the chromosome. Inhibitors of replication proteins are commonly used in anti-cancer and anti-viral therapies. This eBook on “The DNA Replication Machinery as Therapeutic Targets” examines the normal functions of replication proteins as well as strategies to target each step during the replication process including DNA unwinding, DNA synthesis, and DNA damage bypass and repair. Articles discuss current strategies to develop drugs targeting DNA replication proteins as well as future outlooks and needs.

The Mechanisms of DNA Replication

The Mechanisms of DNA Replication Book
Author : David Stuart
Publisher : IntechOpen
Release : 2013-02-20
ISBN : 9789535109914
Language : En, Es, Fr & De

GET BOOK

Book Description :

DNA replication is a fundamental part of the life cycle of all organisms. Not surprisingly many aspects of this process display profound conservation across organisms in all domains of life. The chapters in this volume outline and review the current state of knowledge on several key aspects of the DNA replication process. This is a critical process in both normal growth and development and in relation to a broad variety of pathological conditions including cancer. The reader will be provided with new insights into the initiation, regulation, and progression of DNA replication as well as a collection of thought provoking questions and summaries to direct future investigations.

DNA Helicases and DNA Motor Proteins

DNA Helicases and DNA Motor Proteins Book
Author : Maria Spies
Publisher : Springer Science & Business Media
Release : 2012-11-19
ISBN : 1461450373
Language : En, Es, Fr & De

GET BOOK

Book Description :

In recent years, a number of groundbreaking structural and mechanistic studies deepened our understanding of helicase mechanisms and established new approaches for their analyses. Many fundamental mechanistic questions ranging from the mechanism of force generation, mechanochemical coupling to distinct mechanisms by which the same enzyme translocates on DNA removing obstacles, unwinds DNA and/or remodels nucleoprotein complexes, however, remain to be answered. It is even less understood how the helicase motors are incorporated into a wide range of genome maintenance and repair machines. The field has reached a stage when the studies of molecular mechanisms and basic biology of helicases can and shall be integrated with the studies of development, cancer and longevity. The objective of this book is to provide the first systematic overview of structure, function and regulation of DNA helicases and related molecular motors. By integrating the knowledge obtained through the diverse technical approaches ranging from single-molecule biophysics to cellular and molecular biological studies the editors aim to provide a unified view on how helicases function in the cell, are regulated in response to different cellular stresses and are integrated into large macromolecular assemblies to form a complex and adaptive living system.

Metagenomic Systems Biology

Metagenomic Systems Biology Book
Author : Shailza Singh
Publisher : Springer Nature
Release : 2021-01-08
ISBN : 9811585628
Language : En, Es, Fr & De

GET BOOK

Book Description :

The book serves as an amalgamation of knowledge and principles used in the area of systems and synthetic biology, and targets inter-disciplinary research groups. The readers from diversified areas would be benefited by the valuable resources and information available in one book. Microbiome projects with efficient data handling can fuel progress in the area of microbial synthetic biology by providing a ready to use plug and play chassis. Advances in gene editing technology such as the use of tailor made synthetic transcription factors will further enhance the availability of synthetic devices to be applied in the fields of environment, agriculture and health. The different chapters of the book reviews a broad range of topics, including food microbiome in ecology, use of microbiome in personalized medicine, machine learning in biomedicine. The book also describes ways to harness and exploit the incredible amounts of genomic data. The book is not only limited to medicine but also caters to the needs of environmentalists, biochemical engineers etc. It will be of interest to advanced students and researchers in life sciences, computational biology, microbiology and other inter-disciplinary areas.

The Mechanisms of DNA Replication

The Mechanisms of DNA Replication Book
Author : David Stuart
Publisher : IntechOpen
Release : 2013-02-20
ISBN : 9789535109914
Language : En, Es, Fr & De

GET BOOK

Book Description :

DNA replication is a fundamental part of the life cycle of all organisms. Not surprisingly many aspects of this process display profound conservation across organisms in all domains of life. The chapters in this volume outline and review the current state of knowledge on several key aspects of the DNA replication process. This is a critical process in both normal growth and development and in relation to a broad variety of pathological conditions including cancer. The reader will be provided with new insights into the initiation, regulation, and progression of DNA replication as well as a collection of thought provoking questions and summaries to direct future investigations.

The Mechanisms of DNA Replication

The Mechanisms of DNA Replication Book
Author : David Stuart
Publisher : IntechOpen
Release : 2013-02-20
ISBN : 9789535109914
Language : En, Es, Fr & De

GET BOOK

Book Description :

DNA replication is a fundamental part of the life cycle of all organisms. Not surprisingly many aspects of this process display profound conservation across organisms in all domains of life. The chapters in this volume outline and review the current state of knowledge on several key aspects of the DNA replication process. This is a critical process in both normal growth and development and in relation to a broad variety of pathological conditions including cancer. The reader will be provided with new insights into the initiation, regulation, and progression of DNA replication as well as a collection of thought provoking questions and summaries to direct future investigations.

Molecular Themes in DNA Replication

Molecular Themes in DNA Replication Book
Author : Lynne S Cox
Publisher : Royal Society of Chemistry
Release : 2009-10-31
ISBN : 1847559859
Language : En, Es, Fr & De

GET BOOK

Book Description :

DNA replication, the process of copying one double stranded DNA molecule to form two identical copies, is highly conserved at the mechanistic level across evolution. Interesting in its own right as a fascinating feat of biochemical regulation and coordination, DNA replication is at the heart of modern advances in molecular biology. An understanding of the process at both the biological and chemical level is essential to developing new techniques in molecular biology. Insights into the process at the molecular level provide opportunities to modulate and intervene in replication. Rapidly dividing cells need to replicate their DNA prior to division, and targeting components of the replication process is a potentially powerful strategy in cancer treatment. Conversely, ageing may be associated with loss of replication activity and restoring it to cells may moderate some of the diseases associated with old age. Replication is, therefore, fundamental to a huge range of molecular biological and biochemical applications, and provides many potential targets for drug design. The fast pace of replication research, particularly in providing new structural insights, has outdated the majority of available texts. This learned, yet accessible, book contains the latest research written by those conducting it. It examines conserved themes providing a biological background for biochemical, chemical and pharmaceutical studies of this huge and exciting field. Rather than simply "itemising" the replication steps and the proteins involved, replication is tackled from a novel perspective. The book provides logical groupings of processes based upon biochemical similarities. The emphasis on mechanisms and the relationship between structure and function targets the chapters towards biochemists and biological chemists as well as molecular and cell biologists. The book highlights new insights into the replication process, from the assembly of pre-replication complexes, through polymerisation mechanisms, to considering replication in the context of chromatin and chromosomes. It also covers mitochondrial DNA replication, and includes archaeal paradigms, which are proving increasingly relevant to the study of replication in higher eukaryotes. Exciting potential drug targets in DNA replication are discussed, particularly in the context of treating malaria and cancer.

DNA Repair

DNA Repair Book
Author : Anonim
Publisher : Academic Press
Release : 2019-10-16
ISBN : 0128173971
Language : En, Es, Fr & De

GET BOOK

Book Description :

DNA Repair, Volume 45 in The Enzymes series highlights new advances in the field, with this new volume presenting interesting chapters on DNA polymerase beta and other gap-filling enzymes in mammalian base excision repair, Translesion polymerases, mechanism and function, The Rev1-Pol? Mutasome: Structure and Interactions in Translesion Synthesis, Challenges for base excision repair enzymes: acquiring access to damaged DNA in chromatin Nucleotide excision repair, DNA damage recognition mechanisms in mammalian nucleotide excision repair, Advances in understanding DNA mismatch repair, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in The Enzymes series

DNA Replication Controls Volume 1

DNA Replication Controls  Volume 1 Book
Author : Eishi Noguchi
Publisher : MDPI
Release : 2018-04-27
ISBN : 3038425680
Language : En, Es, Fr & De

GET BOOK

Book Description :

This book is a printed edition of the Special Issue "DNA Replication Controls" that was published in Genes

The Mechanisms of DNA Replication

The Mechanisms of DNA Replication Book
Author : David Stuart
Publisher : IntechOpen
Release : 2013-02-20
ISBN : 9789535109914
Language : En, Es, Fr & De

GET BOOK

Book Description :

DNA replication is a fundamental part of the life cycle of all organisms. Not surprisingly many aspects of this process display profound conservation across organisms in all domains of life. The chapters in this volume outline and review the current state of knowledge on several key aspects of the DNA replication process. This is a critical process in both normal growth and development and in relation to a broad variety of pathological conditions including cancer. The reader will be provided with new insights into the initiation, regulation, and progression of DNA replication as well as a collection of thought provoking questions and summaries to direct future investigations.

Joint Polish German Crystallographic Meeting February 24 27 2020 Wroc aw Poland

Joint Polish German Crystallographic Meeting  February 24   27  2020  Wroc  aw  Poland Book
Author : Anonim
Publisher : Walter de Gruyter GmbH & Co KG
Release : 2020-02-24
ISBN : 3110692910
Language : En, Es, Fr & De

GET BOOK

Book Description :

Zeitschrift für Kristallographie. Supplement Volume 40 presents the complete Abstracts of all contributions to the Joint Polish-German Crystallographic Meeting in Wroclaw (Poland) 2020: - Plenary Talks - Microsymposia - Poster Session Supplement Series of Zeitschrift für Kristallographie publishes Abstracts of international conferences on the interdisciplinary field of crystallography.

Protein Dimerization and Oligomerization in Biology

Protein Dimerization and Oligomerization in Biology Book
Author : Jacqueline M. Matthews
Publisher : Springer Science & Business Media
Release : 2012-09-04
ISBN : 1461432294
Language : En, Es, Fr & De

GET BOOK

Book Description :

This volume has a strong focus on homo-oligomerization, which is surprisingly common. However, protein function is so often linked to both homo- and hetero-oligomerization and many heterologous interactions likely evolved from homologous interaction, so this volume also covers many aspects of hetero-oligomerization.

Molecular Biophysics for the Life Sciences

Molecular Biophysics for the Life Sciences Book
Author : Norma Allewell,Linda O. Narhi,Ivan Rayment
Publisher : Springer Science & Business Media
Release : 2013-09-28
ISBN : 1461485487
Language : En, Es, Fr & De

GET BOOK

Book Description :

This volume provides an overview of the development and scope of molecular biophysics and in-depth discussions of the major experimental methods that enable biological macromolecules to be studied at atomic resolution. It also reviews the physical chemical concepts that are needed to interpret the experimental results and to understand how the structure, dynamics, and physical properties of biological macromolecules enable them to perform their biological functions. Reviews of research on three disparate biomolecular machines—DNA helicases, ATP synthases, and myosin--illustrate how the combination of theory and experiment leads to new insights and new questions.

Handbook of Molecular Microbial Ecology II

Handbook of Molecular Microbial Ecology II Book
Author : Frans J. de Bruijn
Publisher : John Wiley & Sons
Release : 2011-10-14
ISBN : 1118010531
Language : En, Es, Fr & De

GET BOOK

Book Description :

The premiere two-volume reference on revelations from studying complex microbial communities in many distinct habitats Metagenomics is an emerging field that has changed the way microbiologists study microorganisms. It involves the genomic analysis of microorganisms by extraction and cloning of DNA from a group of microorganisms, or the direct use of the purified DNA or RNA for sequencing, which allows scientists to bypass the usual protocol of isolating and culturing individual microbial species. This method is now used in laboratories across the globe to study microorganism diversity and for isolating novel medical and industrial compounds. Handbook of Molecular Microbial Ecology is the first comprehensive two-volume reference to cover unculturable microorganisms in a large variety of habitats, which could not previously have been analyzed without metagenomic methodology. It features review articles as well as a large number of case studies, based largely on original publications and written by international experts. This second volume, Metagenomics in Different Habitats, covers such topics as: Viral genomes Metagenomics studies in a variety of habitats, including marine environments and lakes, soil, and human and animal digestive tracts Other habitats, including those involving microbiome diversity in human saliva and functional intestinal metagenomics; diversity of archaea in terrestrial hot springs; and microbial communities living at the surface of building stones Biodegradation Biocatalysts and natural products A special feature of this book is the highlighting of the databases and computer programs used in each study; they are listed along with their sites in order to facilitate the computer-assisted analysis of the vast amount of data generated by metagenomic studies. Such studies in a variety of habitats are described here, which present a large number of different system-dependent approaches in greatly differing habitats. Handbook of Molecular Microbial Ecology II is an invaluable reference for researchers in metagenomics, microbial ecology, microbiology, and environmental microbiology; those working on the Human Microbiome Project; microbial geneticists; and professionals in molecular microbiology and bioinformatics.

Issues in Life Sciences Bacteriology Parasitology and Virology 2011 Edition

Issues in Life Sciences  Bacteriology  Parasitology  and Virology  2011 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2012-01-09
ISBN : 1464964238
Language : En, Es, Fr & De

GET BOOK

Book Description :

Issues in Life Sciences: Bacteriology, Parasitology, and Virology: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Life Sciences—Bacteriology, Parasitology, and Virology. The editors have built Issues in Life Sciences: Bacteriology, Parasitology, and Virology: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Life Sciences—Bacteriology, Parasitology, and Virology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Life Sciences: Bacteriology, Parasitology, and Virology: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

RNA Polymerases as Molecular Motors

RNA Polymerases as Molecular Motors Book
Author : Robert Landick,Terence Strick,Jue Wang
Publisher : Royal Society of Chemistry
Release : 2021-11-23
ISBN : 1839160667
Language : En, Es, Fr & De

GET BOOK

Book Description :

To thrive, every living cell must continuously gauge and respond to changes in its environment. These changes are ultimately implemented by modulating gene expression, a process that relies on transcription by Nature’s most multivalent molecular machine, the RNA polymerase. This book covers progress made over the past decade understanding how this machine functions to compute the cellular state, from the atomistic structural level responsible for chemistry to the integrative level at which RNA polymerase interacts with the other key molecular machineries of the cell.

RNA Metabolism and Gene Expression in Archaea

RNA Metabolism and Gene Expression in Archaea Book
Author : Béatrice Clouet-d'Orval
Publisher : Springer
Release : 2017-10-28
ISBN : 331965795X
Language : En, Es, Fr & De

GET BOOK

Book Description :

This book focuses on the regulation of transcription and translation in Archaea and arising insights into the evolution of RNA processing pathways. From synthesis to degradation and the implications of gene expression, it presents the current state of knowledge on archaeal RNA biology in 13 chapters. Topics covered include the modification and maturation of RNAs, the function of small non-coding RNAs and the CRISPR-Cas defense system. While Archaea have long been considered exotic microbial extremophiles, they are now increasingly being recognized as important model microorganisms for the study of molecular mechanisms conserved across the three domains of life, and with regard to the relevance of similarities and differences to eukaryotes and bacteria. This unique book offers a valuable resource for all readers interested in the regulation of gene expression in Archaea and RNA metabolism in general.

Encyclopedia of Cell Biology

Encyclopedia of Cell Biology Book
Author : Anonim
Publisher : Academic Press
Release : 2015-08-07
ISBN : 0123947960
Language : En, Es, Fr & De

GET BOOK

Book Description :

The Encyclopedia of Cell Biology offers a broad overview of cell biology, offering reputable, foundational content for researchers and students across the biological and medical sciences. This important work includes 285 articles from domain experts covering every aspect of cell biology, with fully annotated figures, abundant illustrations, videos, and references for further reading. Each entry is built with a layered approach to the content, providing basic information for those new to the area and more detailed material for the more experienced researcher. With authored contributions by experts in the field, the Encyclopedia of Cell Biology provides a fully cross-referenced, one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences. Fully annotated color images and videos for full comprehension of concepts, with layered content for readers from different levels of experience Includes information on cytokinesis, cell biology, cell mechanics, cytoskeleton dynamics, stem cells, prokaryotic cell biology, RNA biology, aging, cell growth, cell Injury, and more In-depth linking to Academic Press/Elsevier content and additional links to outside websites and resources for further reading A one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences