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Harnessing The Power Of Viruses

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Harnessing the Power of Viruses

Harnessing the Power of Viruses Book
Author : Boriana Marintcheva
Publisher : Academic Press
Release : 2017-11-13
ISBN : 9780128105146
Language : En, Es, Fr & De

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Book Description :

Harnessing the Power of Viruses explores the application of scientific knowledge about viruses and their lives to solve practical challenges and further advance molecular sciences, medicine and agriculture. The book contains virus-based tools and approaches in the fields of: i) DNA manipulations in vitro and in vivo; ii) Protein expression and characterization; and iii) Virus- Host interactions as a platform for therapy and biocontrol are discussed. It steers away from traditional views of viruses and technology, focusing instead on viral molecules and molecular processes that enable science to better understand life and offer means for addressing complex biological phenomena that positively influence everyday life. The book is written at an intermediate level and is accessible to novices who are willing to acquire a basic level of understanding of key principles in molecular biology, but is also ideal for advanced readers interested in expanding their biological knowledge to include practical applications of molecular tools derived from viruses. Explores virus-based tools and approaches in DNA manipulation, protein expression and characterization and virus-host interactions Provides a dedicated focus on viral molecules and molecular processes that enable science to better understand life and address complex biological phenomena Includes an overview of modern technologies in biology that were developed using viral components/elements and knowledge about viral processes

Harnessing the Power of Viruses

Harnessing the Power of Viruses Book
Author : Boriana Marintcheva
Publisher : Academic Press
Release : 2017-11-13
ISBN : 0128105151
Language : En, Es, Fr & De

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Book Description :

Harnessing the Power of Viruses explores the application of scientific knowledge about viruses and their lives to solve practical challenges and further advance molecular sciences, medicine and agriculture. The book contains virus-based tools and approaches in the fields of: i) DNA manipulations in vitro and in vivo; ii) Protein expression and characterization; and iii) Virus- Host interactions as a platform for therapy and biocontrol are discussed. It steers away from traditional views of viruses and technology, focusing instead on viral molecules and molecular processes that enable science to better understand life and offer means for addressing complex biological phenomena that positively influence everyday life. The book is written at an intermediate level and is accessible to novices who are willing to acquire a basic level of understanding of key principles in molecular biology, but is also ideal for advanced readers interested in expanding their biological knowledge to include practical applications of molecular tools derived from viruses. Explores virus-based tools and approaches in DNA manipulation, protein expression and characterization and virus-host interactions Provides a dedicated focus on viral molecules and molecular processes that enable science to better understand life and address complex biological phenomena Includes an overview of modern technologies in biology that were developed using viral components/elements and knowledge about viral processes

The Science of Cancer

The Science of Cancer Book
Author : Scientific American Editors
Publisher : Scientific American
Release : 2017-03-20
ISBN : 1466859075
Language : En, Es, Fr & De

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Book Description :

The past few years have seen tremendous strides in our understanding of cancer, including new hypotheses about its genetic origins and new treatment alternatives using the body’s own immune response. In this eBook, The Science of Cancer, we examine what we know and what we’re finding out about this scourge of humankind. We delve into the molecular basis and complex causes of cancer, the arguments for and against screenings, new and targeted therapies, and minimizing risk. In “How Cancer Arises,” Robert Weinberg presents what has been the central dogma of cancer genetics, which says that a handful of essential mutations in specific genes lead to tumor growth; however, recent discoveries are challenging this theory, as we see in “Untangling the Roots of Cancer” and “Stem Cells: The Real Culprits in Cancer?” Early detection of cancer is important for treatment, but not all screening tests are created equal. In “The Great Prostate Cancer Debate,” Mark Garnick lays out the controversy over the value of the prostate-specific antigen test for prostate cancer and the rationale against screening. With our increasing knowledge of cancer’s causes, exciting targeted therapies are on the rise, including homing in on stem cells, making use of viruses, and manipulating the immune system as we see in “A New Ally against Cancer,” which focuses on treatment with therapeutic vaccines. Does this mean a cure is around the corner? Perhaps not, according to Scientific American Editor Dina Fine Maron in “Can We Truly ‘Cure’ Cancer?” But with remission rates rising for certain types of cancers and with new discoveries opening up further avenues of research, there is reason for optimism.

Bioinspired Structures and Design

Bioinspired Structures and Design Book
Author : Wole Soboyejo,Leo Daniel
Publisher : Cambridge University Press
Release : 2020-09-17
ISBN : 1107015588
Language : En, Es, Fr & De

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Book Description :

Human cortical bone as a structural material : Hierarchical design and biological degradation / Robert Ritchie and Elizabeth A. Zimmermann -- Bio-inspiration from nacre / Nima Rahbar and Sina Askarinejad -- Bio-inspiration from bamboo / Ting Tan and Wole Soboyejo.

Clinical Trials in the Neurosciences

Clinical Trials in the Neurosciences Book
Author : Katherine M. Woodbury-Harris,Bruce M. Coull
Publisher : Karger Medical and Scientific Publishers
Release : 2009
ISBN : 3805590237
Language : En, Es, Fr & De

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Book Description :

A properly designed and executed clinical trial that addresses an import question and delivers a definitive result can change the practice of medicine worldwide. This book encompasses a bench-to-bedside approach and serves as an excellent guidance for translating preclinical studies to early phase I/II and phase III trials. In the first part, the book covers preclinical science with respect to animal models of various neurological diseases, FDA requirements for preclinical studies, translation of animal to patient studies and scaling up from animal to human studies. In the second part, the design of phase I/II trials and the use of biomarkers as surrogate endpoints are discussed. With regard to phase III trials, FDA and European requirements, specific design issues, relevant clinical endpoints as well as data management and quality are examined. Topics specific to multicenter trials, such as design, recruitment of special populations, monitoring, ethical and consent issues are also covered. Finally, genetics, gene therapy, imaging and surgical devices are reviewed.This publication is highly recommended to clinician researchers, such as neurologists, neurosurgeons, pediatric neurologists and neonatologists, who want to design and conduct clinical trials in the neuroscience, but also to nurses, research coordinators and clinical pharmacologists.

Respiratory Protection Against Hazardous Biological Agents

Respiratory Protection Against Hazardous Biological Agents Book
Author : Katarzyna Majchrzycka,Małgorzata Okrasa,Justyna Szulc
Publisher : CRC Press
Release : 2020-07-26
ISBN : 1000093735
Language : En, Es, Fr & De

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Book Description :

‘Protection against harmful bioaerosol is one of today’s major concerns. This applies both to people inside and outside the work environment. In this book, renowned scientists provide up-to-date and authoritative reviews of the latest scientific research and practice that has contributed to our understanding of the harmfulness of the bioaerosol and protection against it. A detailed discussion of bioaerosol protection methods and equipment as well as presenting future trends in prognostic modelling are the undeniable value of this monograph. This comprehensive book is indispensable for anyone involved in occupational and environmental hygiene, biological hazard, recognition and control in occupational and public environments’. — Bogumił Brycki, Adam Mickiewicz University The threats of biological airborne hazards are a global danger throughout the world today. Respiratory Protection Against Hazardous Biological Agents covers sources and practices of bioaerosol sampling, and discusses the prevention of these airborne hazards. The most common workplace hazard is poor air quality. The book provides the basic principles of a safe work environment in the conditions where workers might be exposed to harmful bioaerosols. It presents key characteristics of biological hazards and their effects on the human body. It examines microbial growth in filtering materials and provides the details of specific risks for users of respiratory protective devices. The book will present the reader a guide on how to measure the risk of exposure of biological agents and properly select respiratory protective devices. The book is ideal for the health and safety professionals and experts in the field of environmental health. FEATURES: Evaluates the risk of exposure to biological agents Describes the characteristics of biological factors and their effects on the human body Provides training on the importance of respiratory protective devices Examines microorganisms in the work environment Provides examples and case studies

Bugs as Drugs

Bugs as Drugs Book
Author : Robert A. Britton,Patrice D. Cani
Publisher : John Wiley & Sons
Release : 2020-07-02
ISBN : 1555819702
Language : En, Es, Fr & De

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Book Description :

Examining the enormous potential of microbiome manipulation to improve health Associations between the composition of the intestinal microbiome and many human diseases, including inflammatory bowel disease, cardiovascular disease, metabolic disorders, and cancer, have been elegantly described in the past decade. Now, whole-genome sequencing, bioinformatics, and precision gene-editing techniques are being combined with centuries-old therapies, such as fecal microbiota transplantation, to translate current research into new diagnostics and therapeutics to treat complex diseases. Bugs as Drugs provides a much-needed overview of microbes in therapies and will serve as an excellent resource for scientists and clinicians as they carry out research and clinical studies on investigating the roles the microbiota plays in health and disease. In Bugs as Drugs, editors Robert A. Britton and Patrice D. Cani have assembled a fascinating collection of reviews that chart the history, current efforts, and future prospects of using microorganisms to fight disease and improve health. Sections cover traditional uses of probiotics, next-generation microbial therapeutics, controlling infectious diseases, and indirect strategies for manipulating the host microbiome. Topics presented include: How well-established probiotics support and improve host health by improving the composition of the intestinal microbiota of the host and by modulating the host immune response. The use of gene editing and recombinant DNA techniques to create tailored probiotics and to characterize next-generation beneficial microbes. For example, engineering that improves the anti-inflammatory profile of probiotics can reduce the number of colonic polyps formed, and lactobacilli can be transformed into targeted delivery systems carrying therapeutic proteins or bioengineered bacteriophage. The association of specific microbiota composition with colorectal cancer, liver diseases, osteoporosis, and inflammatory bowel disease. The gut microbiota has been proposed to serve as an organ involved in regulation of inflammation, immune function, and energy homeostasis. Fecal microbiota transplantation as a promising treatment for numerous diseases beyond C. difficile infection. Practical considerations for using fecal microbiota transplantation are provided, while it is acknowledged that more high-quality evidence is needed to ascertain the importance of strain specificity in positive treatment outcomes. Because systems biology approaches and synthetic engineering of microbes are now high-throughput and cost-effective, a much wider range of therapeutic possibilities can be explored and vetted.

Emerging Viruses in Human Populations

Emerging Viruses in Human Populations Book
Author : Edward Tabor
Publisher : Elsevier
Release : 2006-12-19
ISBN : 9780080467900
Language : En, Es, Fr & De

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Book Description :

Infectious diseases are an ever present threat to humans. In recent years, the threat of these emerging viruses has been greater than ever before in human history, due in large part to global travel by larger numbers of people, and to a lesser extent to disruptions in the interface between developed and undeveloped areas. The emergence of new deadly viruses in human populations during recent decades has confirmed this risk. They remain the third leading cause of deaths in the US and the second world-wide. Emerging Viruses in Human Populations provides a comprehensive review of viruses that are emerging or that threaten to emerge among human populations in the twenty-first century. It discusses the apprehension over emerging viruses that has intensified due to concerns about bioterrorism. * Presents the history of emerging viruses * Includes chapters on SARS, Pandemic Threat of Avian Influenza Viruses, West Nile Virus, Monkeypox Virus, Hantavirus, Nipah Virus and Hendra Virus, Japanese Encephalitis Virus, Dengue and Crimean-Congo Hemorrhagic Fever Viruses * Discusses surveillance for newly emerging diseases

Tumour Viruses

Tumour Viruses Book
Author : Joanna Parish
Publisher : MDPI
Release : 2018-10-02
ISBN : 3038421510
Language : En, Es, Fr & De

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Book Description :

This book is a printed edition of the Special Issue "Tumour Viruses" that was published in Viruses

Cancer Associated Viruses

Cancer Associated Viruses Book
Author : Erle S. Robertson
Publisher : Springer Science & Business Media
Release : 2012-02-14
ISBN : 1461400163
Language : En, Es, Fr & De

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Book Description :

The acknowledgment that viruses are potent biological factors in driving many cancers have seen a dramatic upsurge in recent years in large part to the success of the human papilloma virus vaccine against invasive cervical carcinomas and followed by the awarding of the noble prize in medicine in 2008 to Dr. Harald zurHausen who identified the link between papilloma virus and cervical cancers. Over the last few years there have been some volumes addressing different aspects of viruses and cancers and to some extent focusing on the DNA viruses, more specifically the human DNA viruses. This proposed volume will attempt to review and address the major gaps in current knowledge in DNA viruses as well as RNA viruses bringing a historical perspective of where studies began to a more recent molecular approach and vaccine successes in tumor viruses. We will also cover other known oncogenic viruses associated cancers in other mammals in addition to humans.

The First Shots

The First Shots Book
Author : Brendan Borrell
Publisher : Houghton Mifflin Harcourt
Release : 2021
ISBN : 0358569842
Language : En, Es, Fr & De

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Book Description :

An award-winning journalist, drawing on high-level access, presents the full inside story of the high-stakes, global race of the lifesaving vaccine to end the pandemic.

Stealth Adapted Viruses Alternative Cellular Energy ACE KELEA Activated Water

Stealth Adapted Viruses  Alternative Cellular Energy  ACE    KELEA Activated Water Book
Author : W. John Martin, MD, PhD.
Publisher : AuthorHouse
Release : 2014-06-09
ISBN : 1496904974
Language : En, Es, Fr & De

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Book Description :

This book is intended to help mankind realize the many medical and agricultural benefits of enhancing the alternative cellular energy (ACE) pathway. The research stemmed from the discovery of stealth adapted viruses, which bypass cellular immunity. Stealth adapted viruses were implicated in mental illnesses over 20 years ago. The concept evoked political resistance because some stealth adapted viruses unequivocally arose as contaminants of polio vaccines and likely led to the formation of HIV, the AIDS virus. The ACE pathway is distinct from the immune system. It also fundamentally differs from cellular energy obtained from food calories. Rather the ACE pathway is an expression of a “kinetic energy limiting electrostatic attraction” or KELEA. The physics of KELEA needs to be actively pursued. The book consists of six-academic-style chapters followed by narratives regarding political barriers and specific disease entities. Patients’ support groups and other organizations will be assisted in conducting their own clinical validation studies. Let the work begin!

Viral Therapy of Cancer

Viral Therapy of Cancer Book
Author : Kevin J. Harrington
Publisher : John Wiley & Sons
Release : 2008-05-23
ISBN : 047098578X
Language : En, Es, Fr & De

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Book Description :

In the last decade there has been an explosion of interest in viral therapies for cancer. Viral agents have been developed that are harmless to normal tissues but selectively able to kill cancer cells. These agents have been endowed with additional selectivity and potency through genetic manipulation. Increasingly these viruses are undergoing evaluation in clinical trials, both as single agents and in combination with standard chemotherapy and radiotherapy. This book provides a comprehensive yet succinct overview of the current status of viral therapy of cancer. Chapters coherently present the advances made with individual agents and review the biological and clinical background to a range of viral therapies: structured to proceed from basic science at the bench to the patient’s bedside, they give an up-to-date and realistic evaluation of a therapy’s potential utility for the cancer patient. Presents state of the art knowledge on how viruses can be, and have been, used in novel therapeutic approaches for the treatment of cancer Describes the use of viruses as oncolytic agents, killing cells directly Editors are experts in the field, with experience of both laboratory and clinical research Viral Therapy of Cancer is essential reading for both basic scientists and clinicians with an interest in viral therapy and gene therapy.

New Media Old Media

New Media  Old Media Book
Author : Wendy Hui Kyong Chun,Thomas Keenan
Publisher : Psychology Press
Release : 2006
ISBN : 9780415942249
Language : En, Es, Fr & De

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Book Description :

In this history of new media technologies, leading media and cultural theorists examine new media against the background of traditional media such as film, photography, and print in order to evaluate the multiple claims made about the benefits and freedom of digital media.

Wyrm

Wyrm Book
Author : Mark Fabi
Publisher : Spectra
Release : 1997
ISBN : 9780553378719
Language : En, Es, Fr & De

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Book Description :

Hired to eliminate viruses from the computers of large corporations, Michael Arcangelo discovers a strange new "Wyrm" infesting programs across the country--a naturally evolved, intelligent bug bent on destruction. Original.

Clinical Applications of Immunomics

Clinical Applications of Immunomics Book
Author : Andras Falus
Publisher : Springer Science & Business Media
Release : 2008-12-23
ISBN : 9780387792088
Language : En, Es, Fr & De

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Book Description :

Innate immunity is one the most evolutionally conserved systems, designed to protect the organism from viruses and bacterial infections, stress and many other types of attacks from the outside world. During the past decade, the capacity of molecular biology and information technology to produce and analyse data have grown exponentially, rapidly reforming many aspects of immunology research in the post-genomics era. As a result, scientific understanding of signalling networks governing the innate immunity response in human tissues and other organisms has evolved beyond recognition, compared to even just a decade ago. Many strategies have been designed over the years to identify novel proteins, which have a crucial role in innate immunity responses by regulating particular signalling pathways. These projects had many advantages, including the definition of novel drug targets, as exemplified by the recent success of anti-TNF therapy, as well as leading to a better, system-wide understanding of the molecular control of innate immunity. In the past few years, a new concept, Immunomics, has been adopted to define an emerging, multidisciplinary field of research (Schonbach, 2003). Although rapid progress has been made to identify the proteins playing pivotal roles in the innate immunity–related signalling pathways (for example, TIR signalling pathways), the catalogue of proteins with a key regulatory function identified and studied is far from completed. Novel proteins need to be char- terised to gain a more comprehensive picture of how signalling networks are regulated.

Principles and Practice of Endocrinology and Metabolism

Principles and Practice of Endocrinology and Metabolism Book
Author : Kenneth L. Becker
Publisher : Lippincott Williams & Wilkins
Release : 2001
ISBN : 9780781717502
Language : En, Es, Fr & De

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Book Description :

Established as the foremost text in the field, Principles and Practice of Endocrinology and Metabolism is now in its thoroughly revised, updated Third Edition. This practical, clinically relevant, and comprehensive text covers the entire field of endocrinology and metabolism, including the diffuse endocrine system; morphology and physiology; diagnosis and treatment of endocrine diseases; endocrinology of the female; hormones and cancer; and much more. The Third Edition contains new chapters reflecting the latest advances and features expanded coverage of genetics and the endocrinology of sepsis. More than 1,400 illustrations complement the text. A drug formulary appears at the back of the book.

Digital Contagions

Digital Contagions Book
Author : Jussi Parikka
Publisher : Peter Lang
Release : 2007
ISBN : 9780820488370
Language : En, Es, Fr & De

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Book Description :

Digital Contagions is the first book to offer a comprehensive and critical analysis of the culture and history of the computer virus phenomenon. The book maps the anomalies of network culture from the angles of security concerns, the biopolitics of digital systems, and the aspirations for artificial life in software. The genealogy of network culture is approached from the standpoint of accidents that are endemic to the digital media ecology. Viruses, worms, and other software objects are not, then, seen merely from the perspective of anti-virus research or practical security concerns, but as cultural and historical expressions that traverse a non-linear field from fiction to technical media, from net art to politics of software. Jussi Parikka mobilizes an extensive array of source materials and intertwines them with an inventive new materialist cultural analysis. Digital Contagions draws from the cultural theories of Gilles Deleuze and Félix Guattari, Friedrich Kittler, and Paul Virilio, among others, and offers novel insights into historical media analysis.

Antivirals for Emerging Viruses Vaccines and Therapeutics

Antivirals for Emerging Viruses  Vaccines and Therapeutics Book
Author : Lijun Rong,Lu Lu,Christopher C. Broder
Publisher : Frontiers Media SA
Release : 2020-12-22
ISBN : 2889662527
Language : En, Es, Fr & De

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Book Description :

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Artificial Life

Artificial Life Book
Author : Christopher G. Langton
Publisher : MIT Press
Release : 1997
ISBN : 9780262621120
Language : En, Es, Fr & De

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Book Description :

This book brings together a series of overview articles that appeared in the first three issues of the groundbreaking journal Artificial Life.