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Handbook Of Toxicology Of Chemical Warfare Agents

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Handbook of Toxicology of Chemical Warfare Agents

Handbook of Toxicology of Chemical Warfare Agents Book
Author : Ramesh C. Gupta
Publisher : Academic Press
Release : 2009-04-02
ISBN : 9780080922737
Language : En, Es, Fr & De

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Book Description :

This groundbreaking book covers every aspect of deadly toxic chemicals used as weapons of mass destruction and employed in conflicts, warfare and terrorism. Including findings from experimental as well as clinical studies, this one-of-a-kind handbook is prepared in a very user- friendly format that can easily be followed by students, teachers and researchers, as well as lay people. Stand-alone chapters on individual chemicals and major topics allow the reader to easily access required information without searching through the entire book. This is the first book that offers in-depth coverage of individual toxicants, target organ toxicity, major incidents, toxic effects in humans, animals and wildlife, biosensors, biomarkers, on-site and laboratory analytical methods, decontamination and detoxification procedures, prophylactic, therapeutic and countermeasures, and the role of homeland security. Presents a comprehensive look at all aspects of chemical warfare toxicology in one reference work. This saves researchers time in quickly accessing the very latest definitive details on toxicity of specific agents used in chemical warfare as opposed to searching through thousands of journal articles. Will include the most agent-specific information on the market Includes detailed coverage of the most exhaustive list of agents possibly used as chemical warfare agents in one source. Section 4: Agents That Can Be Used as Weapons of Mass Destruction ? 25 chapters long. Other books on the market only include a sample selection of specific agents. Offering all possible agents detailed under one cover makes this appealing to a wider audience and saves researchers time The Forward will be written by Dr. Tetsuo Satoh, Chiba University, Japan. He is one of the most respected, recognizable authorities on chemical warfare agents which will set the authoritative tone for the book Covers risk to humans, animals and the environment equally. Researchers involved in assessing the risks involved with a possible chemical warfare attack and those who are developing response plans to such attacks must look at not only the risks to human health but to our wildlife and environment as well. The holistic approach taken in this book ensures that the researchers have ready access to the details no matter which aspect of the effects of CWA's they might be concerned with

Handbook of Toxicology of Chemical Warfare Agents

Handbook of Toxicology of Chemical Warfare Agents Book
Author : Ramesh C. Gupta
Publisher : Academic Press
Release : 2020-07
ISBN : 9780128190906
Language : En, Es, Fr & De

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Book Description :

Handbook of Toxicology of Chemical Warfare Agents, Third Edition covers every aspect of deadly toxic chemicals used in conflicts, warfare and terrorism. Including findings from experimental as well as clinical studies, this essential reference offers in-depth coverage of individual toxicants, target organ toxicity, major incidents, toxic effects in humans, animals and wildlife, biosensors and biomarkers, on-site and laboratory analytical methods, decontamination and detoxification procedures, and countermeasures. Expanding on the second edition, Handbook of Toxicology of Chemical Warfare Agents has been completely updated, presenting the most recent advances in field. Brand new chapters include a new chapter on emergency preparedness, coverage of the chemical warfare agents used in Syria, the use of the Novichok agent in the UK, and more. Unites world-leading experts to bring you cutting-edge, agent-specific information on Chemical Warfare Agents (CWA) and their adverse effects on human and animal health, and the environment Provides you with all the information you need on CWA modes of action, detection, prevention, therapeutic treatment and countermeasures New to this edition: a full update to reflect the most recent advances in the field and new chapters on emergency preparedness, the chemical warfare agents used in Syria, and the use of the Novichok agent in the UK

Chemical Warfare Agents

Chemical Warfare Agents Book
Author : Timothy T. Marrs,Robert L. Maynard,Frederick Sidell
Publisher : John Wiley & Sons
Release : 2007-04-04
ISBN : 0470060026
Language : En, Es, Fr & De

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Book Description :

Chemical Warfare Agents, Second Edition has been totally revised since the successful first edition and expanded to about three times the length, with many new chapters and much more in-depth consideration of all the topics. The chapters have been written by distinguished international experts in various aspects of chemical warfare agents and edited by an experienced team to produce a clear review of the field. The book now contains a wealth of material on the mechanisms of action of the major chemical warfare agents, including the nerve agent cyclosarin, formally considered to be of secondary importance, as well as ricin and abrin. Chemical Warfare Agents, Second Edition discusses the physico-chemical properties of chemical warfare agents, their dispersion and fate in the environment, their toxicology and management of their effects on humans, decontamination and protective equipment. New chapters cover the experience gained after the use of sarin to attack travellers on the Tokyo subway and how to deal with the outcome of the deployment of riot control agents such as CS gas. This book provides a comprehensive review of chemical warfare agents, assessing all available evidence regarding the medical, technical and legal aspects of their use. It is an invaluable reference work for physicians, public health planners, regulators and any other professionals involved in this field. Review of the First Edition: "What more appropriate time for a title of this scope than in the post 9/11 era? ...a timely, scholarly, and well-written volume which offers much information of immense current and...future benefit." —VETERINARY AND HUMAN TOXICOLOGY

Handbook of Chemical and Biological Warfare Agents

Handbook of Chemical and Biological Warfare Agents Book
Author : D. Hank Ellison
Publisher : CRC Press
Release : 2010-12-12
ISBN : 9781420048308
Language : En, Es, Fr & De

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Book Description :

With terrorist groups expanding their weapons of destruction beyond bombs and bullets, chemical and biological warfare agents aren't merely limited to the battlefield anymore. In some cases, they are now being used on a new front: major metropolitan cities. And in the Handbook of Chemical and Biological Warfare Agents, emergency response personnel-from HazMat and Police SWAT teams to Explosive Ordinance Disposal units-will find a myriad of information on how to deal with such incidents involving dangerous chemical and biological agents. The 504-page book is formatted into a series of indices developed to facilitate rapid access to key information on chemical, biological and toxin agents, with each index cross-referenced to all others. The wealth of data not only include the physical appearance, odor, signs and symptoms of dangerous materials such as nerve agents and vesicants, but the detection and removal of such agents and the treatment of victims. Author D. Hank Ellison, a former U.S. Environmental Protection Agency emergency responder and officer in the Chemical Corps who provides chemical and biological counterterrorism training to HazMat, Police SWAT and Explosive Ordinance Disposal teams, also includes a litany of guidelines from such sources as the US Army, DOT and other agencies.

Toxicology of Organophosphate and Carbamate Compounds

Toxicology of Organophosphate and Carbamate Compounds Book
Author : Ramesh C. Gupta
Publisher : Academic Press
Release : 2011-04-28
ISBN : 9780080543109
Language : En, Es, Fr & De

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Book Description :

This text/reference book provides the most comprehensive coverage of anticholinesterase compounds (Organophosphates and Carbamates), which constitute the largest number of chemicals that are primarily used as insecticides in agriculture, industry, and around the home/garden. Some OPs (nerve agents) have been used in chemical warfare and terrorist attacks, while some OPs and CMs have been recommended as therapeutic agents in human medicine as well as in veterinary medicine. Many chemicals of both classes are extremely toxic and lack selectivity, thus their inadvertent/accidental use continues to pose a threat to human and animal health, aquatic systems and wildlife. These anticholinesterase agents produce a variety of toxicological effects in target and nontarget organs. In light of this complexicity, this multi-authored book is written by the well known scientists from many countries. The book is organized into nine sections, with a total of 49 chapters, to provide in-depth knowledge on various aspects of OP and CM compounds, including their use, classification, mechanism-based toxicity, and prophylactic and therapeutic measurements. Several chapters are written with special emphasis to cover timely topics, such as chemical warfare agents, physiologically-based pharmacokinetic modeling, structure and function of cholinesterases, paraoxonase, carboxylesterases; developmental neurotoxicity, the intermediate syndrome, oxidative stress, endocrine disruption, and DNA damage/gene expression and carcinogenesis. Section-VI with 5 chapters is specifically devoted to risk assessment, and safety and regulatory guidelines for pesticides. Describes everything you need to know about Organophosphates and Carbamates Extensively covers pesticides, nerve agents, therapeutic drugs, and flame retardants Describes epidemiology of the world's major disasters involving Organophosphates and Carbamates Covers animal, human, aquatic, and wildlife toxicity of Anticholinesterases Insights into in-depth cholinergic and noncholinergic mechanisms of toxicity Describes recent advancements in cholinesterases, paraoxonases, carboxylesterases, oxidative stress, endocrine disruption, cardiac and pulmonary toxicity, and carcinogenesis Provides in vitro and in vivo models for neurotoxicity testing Integrates knowledge of studies in lab animals and humans Offers risk/safety assessment and national/international guidelines for permissible levels of pesticide residues Describes management of Anticholinesterase poisoning in humans

Chemical Warfare Agents

Chemical Warfare Agents Book
Author : Brian J. Lukey,M. Somani Satu,James A. Romano Jr.,James A. Romano,Harry Salem
Publisher : CRC Press
Release : 2000-12-07
ISBN : 1420041576
Language : En, Es, Fr & De

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Book Description :

Many books cover the emergency response to chemical terrorism. But what happens after the initial crisis? Chlorine, phosgene, and mustard were used in World War I. Only years after the war were the long-term effects of these gases realized. In the 60s, 70s, and 80s, these and other agents were used in localized wars. Chemical Warfare Agents: Toxicity at Low Levels explores the long range effects of, protection against, and remedies for chemicals used during war and the chronic problems possibly resulting from toxic exposures during the Persian Gulf War.

Emergency Action for Chemical and Biological Warfare Agents

Emergency Action for Chemical and Biological Warfare Agents Book
Author : D. Hank Ellison
Publisher : CRC Press
Release : 1999-09-28
ISBN : 9780849302411
Language : En, Es, Fr & De

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Book Description :

A HazMat team evacuates five square miles of a city business district in response to a chemical spill. Ten city blocks away, a police special response team forms a perimeter around an office building where a terrorist threatens the release of a deadly chemical agent. Meanwhile, paramedics administer first aid to victims exposed to a possible vesicant. In the real-life world of emergency response, nothing is more crucial to crisis personnel than quick and decisive action. D. Hank Ellison's Emergency Action for Chemical and Biological Warfare Agents tells police, paramedics, and firefighters just what actions to take in the event of a crisis involving hazardous materials. The book contains abridged versions of the class indices from Ellison's larger Handbook of Chemical and Biological Warfare Agents. The indices deal with classes of agents (nerve, blister, etc.) instead of focusing on specific agents. Each index contains information on the toxicology/health impacts, physical characteristics, hazards from fire or reactivity, protection of personnel, and general first aid for that agent class. Designed to provide rapid access to critical emergency information at the scene of a release of chemical or biological warfare agents, this handy field guide is also ideal for facilitating the coordination with off-site personnel who have access to more comprehensive information in Ellison's larger Handbook. It differs from its larger companion, however, in that agent specific data, as well as information on evacuation distances, are listed in table format, making it the ideal tool for emergency responders deployed in the field.

Riot Control Agents

Riot Control Agents Book
Author : Eugene J. Olajos,Woodhall Stopford M.D.
Publisher : CRC Press
Release : 2004-01-27
ISBN : 1134424930
Language : En, Es, Fr & De

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Book Description :

The proliferation and sophistication of riot control chemicals mean that all parties need to understand the responsible use and effects of such compounds. This book provides practical information on the history, chemistry, and biology of riot control agents and discusses their biological actions, risk assessment issues, and recent technical develop

Chemical Warfare Agents

Chemical Warfare Agents Book
Author : James A. Romano Jr.,James A. Romano,Harry Salem,Brian J Lukey,Brian J. Lukey
Publisher : CRC Press
Release : 2007-12-17
ISBN : 9781420046625
Language : En, Es, Fr & De

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Book Description :

The first edition of this book, Chemical Warfare Agents: Toxicity at Low Levels, was published just prior to the terrorist attacks of September 11th, 2001. Reflecting a greater sense of urgency within the field of chemical defense since this event, research related to chemical warfare agents (CWAs) continues to expand at a remarkable pace. Chemical Warfare Agents: Pharmacology, Toxicology, and Therapeutics, Second Edition explores the latest methods and products for preventing, diagnosing, and treating the acute and chronic effects of toxic CWA exposure. This edition citesthe key developments in chemical defense research since 2001, including new epidemiological or clinical studies of exposed or potentially exposed populations; new treatment concepts and products; improved organization of the national response apparatus in the U.S. addressing the potential for CWA terrorism; and improved diagnostic tests that enable rapid diagnosis and treatment. Leading researchers explain how these breakthroughs help researchers determine physiologically relevant detection thresholds and develop more effective countermeasures and national response procedures. Chemical Warfare Agents provides first responders and emergency medical teams with the most up-to-date information they need to prepare for and handle natural disasters, chemical spills, terrorism, and warfare situations—quickly and effectively.

Anticholinesterase Pesticides

Anticholinesterase Pesticides Book
Author : Tetsuo Satoh,Ramesh C. Gupta
Publisher : John Wiley & Sons
Release : 2011-03-25
ISBN : 9780470640494
Language : En, Es, Fr & De

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Book Description :

This book offers an important reference source about the most common classes of pesticides for researchers engaged in the area of neurotoxicology, metabolism, and epidemiology. The book presents details about thorough characterization of target and non-target enzymes and proteins involved in toxicity and metabolism; and epidemiology of poisonings and fatalities in people from short- and long- term exposures to these pesticides in different occupational settings on an individual country basis as well as on a global basis. The early portion of the book deals with metabolism, mechanisms and biomonitoring of anticholinesterase pesticides, while the later part deals with epidemiological studies, regulatory issues, and therapeutic intervention.

Forensic Science

Forensic Science Book
Author : Anonim
Publisher : Elsevier
Release : 2011-09-22
ISBN : 9780080554259
Language : En, Es, Fr & De

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Book Description :

The book presents the applications of separation methods, manly chromatography, in forensic practice. The first part, devoted to forensic toxicology, contains reviews on forensic relevant groups of compounds, like: Opiate agonists, cocaine, amphetamines, hallucinogens, cannabinoids, sedatives and hypnotics, antidepressive and antipsychotic drugs, analgesics, antidiabetics, muscle relaxants, and mushroom toxins. In these parts, the preliminary immunochemical tests were also included, together with separation methods. Screening procedures used in forensic toxicology were presented in separate chapters on forensic screening with GC, GC-MS, HPLC, LC-MS, CE, and LC-ICP-MS. In the part on actual and emerging problems of forensic toxicology, following chapters were included: Analytical markers of alcohol abuse, toxicological aspects of herbal remedies, drugs and driving, analysis in alternative matrices, doping analysis, pharmacogenomics in forensic toxicology, and quality assurance. The second part presents application of separation methods in forensic chemistry, and comprises chapters on: Explosives, chemical warfare agents, arson analysis, and writing media. Third part on forensic identification contains chapter on forensic genetics. All chapters are written up-to-date and present specific information up to 2006. The authors of each chapter are known not only from their scientific activity, but are also reputed experts, proven in everyday forensic casework. - Wide spectrum of topics presented - Up-to-date presentation of topics - Data are presented in comparative mode - Special stress put on screening procedures

Chemical Warfare Agents

Chemical Warfare Agents Book
Author : Brian J. Lukey,James A. Romano Jr.,Harry Salem
Publisher : CRC Press
Release : 2019-04-11
ISBN : 0429632967
Language : En, Es, Fr & De

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Book Description :

The first edition of this book, Chemical Warfare Agents: Toxicity at Low Levels, was published just prior to the terrorist attacks of September 11, 2001. The second edition titled, Chemical Warfare Agents: Pharmacology, Toxicology, and Therapeutics, included new epidemiological and clinical studies of exposed or potentially exposed populations; new treatment concepts and products; improved organization of the national response apparatus addressing the potential for CWA terrorism; and improved diagnostic tests that enable rapid diagnosis and treatment. Since the second edition, the chemical warfare agent community has worked hard to advance research for protection and treatment and develop/improve response approaches for individuals and definitive care. Consequently, in addition to updating previous chapters, Chemical Warfare Agents: Biomedical and Psychological Effects, Medical Countermeasures, and Emergency Response, Third Edition features several new chapters that address the Syrian War, chemical destruction, the Organisation for the Prohibition of Chemical Weapons, biomarkers for chemical warfare agent exposure, field sensors, aircraft decontamination, lung/human on a chip, chemical warfare response decision making, and other research advancements. Features: Describes the newest medical interventions, and the latest technologies deployed in the field, as well as developments in the international response to CW usage highlighting recent events in the Middle East Discusses the latest in organizational/interagency partitioning in terms of responsibilities for emergency response, not just in the United States but at the international level—whether prevention, mitigation, medical care, reclamation, or medico-legal aspects of such response Contains the most current research from bench-level experts The third edition contains the most up-to-date and comprehensive coverage of the question of chemical warfare agent employment on the battlefield or in terrorism. Edited by workers that have been in the field for 35+ years, it remains faithful to the scientific "constants," while evaluating and crediting the advances by the industry that have made us safer.

Biomarkers in Toxicology

Biomarkers in Toxicology Book
Author : Ramesh C. Gupta
Publisher : Academic Press
Release : 2019-02-13
ISBN : 0128146567
Language : En, Es, Fr & De

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Book Description :

Biomarkers in Toxicology, Second Edition, is a timely and comprehensive reference dedicated to all aspects of biomarkers that relate to chemical exposure and their effects on biological systems. This revised and completely updated edition includes both vertebrate and non-vertebrate species models for toxicological testing and the development of biomarkers. Divided into several key sections, this reference volume contains new chapters devoted to topics in microplastics, neuroimmunotoxicity and nutraceuticals, along with a look at the latest cutting-edge technologies used to detect biomarkers. Each chapter contains several references to current literature and important resources for further reading. Given this comprehensive treatment, this book is an essential reference for anyone interested in biomarkers across the scientific and biomedical fields. Evaluates the expansive literature, providing one resource covering all aspects of toxicology biomarkers Includes completely revised chapters, along with additional chapters on the newest developments in the field Identifies and discusses the most sensitive, accurate, unique and validated biomarkers used as indicators of exposure Covers special topics and applications of biomarkers, including chapters on molecular toxicology biomarkers, biomarker analysis for nanotoxicology, development of biomarkers for drug efficacy evaluation, and much more

Chemical Warfare Toxicology

Chemical Warfare Toxicology Book
Author : Franz Worek,John Jenner,Horst Thiermann
Publisher : Royal Society of Chemistry
Release : 2016-05-17
ISBN : 1782628037
Language : En, Es, Fr & De

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Book Description :

This book provides an up-to-date treatise on the on-going research into the toxicology of chemical warfare agents, the diagnosis and verification of exposure, and the pre- and post-exposure treatment of poisoning.

Drugs and Poisons in Humans

Drugs and Poisons in Humans Book
Author : Osamu Suzuki,Kanako Watanabe
Publisher : Springer Science & Business Media
Release : 2006-01-16
ISBN : 3540275797
Language : En, Es, Fr & De

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Book Description :

Unique analysis of drugs and poisons to facilitate testing in all laboratories even by inexperienced chemists Includes source of chemicals needed for the experiments Texts are composed by 67 experts in analyzing the respective compounds Clear and uniform structure of chapters for ease of reading The text is illustrated by many diagrams and tables

Nutraceuticals

Nutraceuticals Book
Author : Ramesh C. Gupta
Publisher : Academic Press
Release : 2016-01-28
ISBN : 0128021659
Language : En, Es, Fr & De

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Book Description :

Nutraceuticals: Efficacy, Safety and Toxicity brings together all current knowledge regarding nutraceuticals and their potential toxic effects as written by the scientists at the forefront of their study. Users will find an introduction to nutraceuticals, herbal medicines, ayurvedic medicines, prebiotics, probiotics, and adaptogens, along with their use and specific applications. This essential reference then discusses the mechanism of action for the judicious use of these nutraceuticals and the best tools for their evaluation before detailing the safety and toxicity of nutraceuticals and their interactions with other therapeutic drugs. Finally, and crucially, regulatory aspects from around the world are covered, providing a comprehensive overview of the most effective tools for the evaluation, safety, and toxicity of nutraceuticals, prebiotics, probiotics, and alternative medicines. Grants an overview of the current state-of-the-science of nutraceuticals, their use and applications, and known adverse effects Provides effective tools to evaluate the potential toxicity of any nutraceutical Includes details of regulatory issues as written by international experts

Atlas of Human Poisoning and Envenoming Second Edition

Atlas of Human Poisoning and Envenoming  Second Edition Book
Author : James H. Diaz
Publisher : CRC Press
Release : 2014-11-07
ISBN : 1466505400
Language : En, Es, Fr & De

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Book Description :

Clinicians undergoing competency testing, certification, and periodic recertification are frequently faced with computer-based exams designed to evaluate clinical acumen and judgment. Test questions often include an image or radiograph followed by a vignette of the clinical encounter and a series of questions. Designed to better prepare practitioners for image-intense, computer-based examinations in their respective fields, Atlas of Human Poisoning and Envenoming is a visual and written reminder of the ubiquitous sources of toxins and toxoids in the environment and the outcomes of accidental or intentional toxic exposures in humans. The Second Edition has been restructured with bulleted text, tables, and figures resembling the vignettes that accompany national examinations. Combining the four specialties of toxicology—analytical, medical, environmental, and industrial—into one comprehensive atlas, the book presents photographs and diagrams of toxic plants and animals, their mechanisms of poisoning or envenoming, and the human responses caused by toxic exposure. Highlights of the new edition include: Prescription and illicit drug abuse epidemics Environmental and occupational nephrotoxicology and neurotoxicology Tick paralysis Petrochemical toxicants Biological, chemical, and radiological warfare agents Workplace substance abuse screening and monitoring Epidemiological design and statistical analysis of toxicological investigations The book is conveniently divided into four sections covering general medical toxicology, environmental toxicology, industrial and occupational toxicology, and epidemiology and statistics for toxicology. Supplemented with a 16-page color insert, the second edition includes new images and tables. The atlas will be a useful study guide for a range of practitioners preparing for a lifetime of image-intense national examinations.

Detection Technologies for Chemical Warfare Agents and Toxic Vapors

Detection Technologies for Chemical Warfare Agents and Toxic Vapors Book
Author : Yin Sun
Publisher : CRC Press
Release : 2004-08-12
ISBN : 020348570X
Language : En, Es, Fr & De

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Book Description :

While it is not possible to predict or necessarily prevent terrorist incidents in which chemical warfare agents (CWAs) and toxic industrial chemicals (TICs) are deployed, correctly chosen, fast, and reliable detection equipment will allow prepared rescue workers to respond quickly and minimize potential casualties. Detection Technologies

A Small Dose of Toxicology

A Small Dose of Toxicology Book
Author : Steven G. Gilbert
Publisher : CRC Press
Release : 2004-02-18
ISBN : 0203461738
Language : En, Es, Fr & De

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Book Description :

Everyday, we come into contact with many relatively harmless substances that could, at certain concentrations, be toxic. This applies not only to obvious candidates such as asbestos, lead, and gasoline, but also to compounds such as caffeine and headache tablets. While the field of toxicology has numerous texts devoted to aspects of biology, chemis

Nerve Agents Poisoning and its Treatment in Schematic Figures and Tables

Nerve Agents Poisoning and its Treatment in Schematic Figures and Tables Book
Author : Jiri Bajgar
Publisher : Elsevier
Release : 2012-03-15
ISBN : 0123914825
Language : En, Es, Fr & De

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Book Description :

Organophosphate compounds, first synthesized in the 1800s, have been used for insecticides, pesticides, and in war and terrorism, such as the 1995 Tokyo subway poisoning. This book provides an in-depth examination of the effects of organophosphates and nerve agents and offers therapeutic and prophylactic countermeasures. Beginning with an overview of milestones in the use of toxic chemicals and chemical warfare agents, the formulae and toxicities of compounds are given, along with tables outlining animal toxicities. Data on various compounds’ inhibitions and subsequent accumulations are also provided. Along with data on organophosphates and nerve agents, possible first aid and medical responses are compared among potential responses in the United States and other countries in the east and west. Using clear schematics and tables, this book provides a detailed account of the most common organophosphates and nerve agents, ideas of how to countermeasure their effects, and offers detailed suggestions for where research needs to proceed in the future. This book will prove useful to students, researchers, and military personnel needing to know more about how to deal with nerve agents. Dedicated to organophosphates/nerve agent, this book contains tables on toxicities in animals and simple figures useable for brief orientation and education